Jesse D. Riordan, Ph.D.

Affiliations: 
2013 Anatomy & Cell Biology University of Iowa, Iowa City, IA 
Area:
Genetics, Molecular Biology, Oncology
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"Jesse Riordan"

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Adam J. Dupuy grad student 2013 University of Iowa
 (A forward genetics approach to identify molecular drivers of liver cancer using Sleeping Beauty mouse models.)
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Publications

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Schillo JL, Feddersen CR, Peplinski RM, et al. (2024) Single-cell genomics analysis reveals complex genetic interactions in an model of acquired BRAF inhibitor resistance. Nar Cancer. 6: zcad061
Zhu EY, Schillo JL, Murray SD, et al. (2023) Understanding cancer drug resistance with functional genomic screens: Application to MAPK inhibition in cutaneous melanoma. Iscience. 26: 107805
Zhu EY, Riordan JD, Vanneste M, et al. (2022) SRC-RAC1 signaling drives drug resistance to BRAF inhibition in de-differentiated cutaneous melanomas. Npj Precision Oncology. 6: 74
Sun F, Cheng Y, Riordan JD, et al. (2021) WDR26 and MTF2 are therapeutic targets in multiple myeloma. Journal of Hematology & Oncology. 14: 203
Blanc V, Riordan JD, Soleymanjahi S, et al. (2021) Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer. The Journal of Clinical Investigation. 131
Feddersen CR, Schillo JL, Varzavand A, et al. (2019) Src-dependent DBL family members drive resistance to vemurafenib in human melanoma. Cancer Research
Feddersen CR, Wadsworth LS, Zhu EY, et al. (2019) A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. Bmc Genomics. 20: 497
Ziyad S, Riordan JD, Cavanaugh AM, et al. (2018) A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224
Tschida BR, Temiz NA, Kuka TP, et al. (2017) Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor. Cancer Research
Riordan JD, Feddersen CR, Tschida BR, et al. (2017) Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma. Hepatology (Baltimore, Md.)
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