Jesse D. Riordan, Ph.D.

Affiliations: 
2013 Anatomy & Cell Biology University of Iowa, Iowa City, IA 
Area:
Genetics, Molecular Biology, Oncology
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"Jesse Riordan"

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Adam J. Dupuy grad student 2013 University of Iowa
 (A forward genetics approach to identify molecular drivers of liver cancer using Sleeping Beauty mouse models.)
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Publications

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Feddersen CR, Schillo JL, Varzavand A, et al. (2019) Src-dependent DBL family members drive resistance to vemurafenib in human melanoma. Cancer Research
Feddersen CR, Wadsworth LS, Zhu EY, et al. (2019) A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells. Bmc Genomics. 20: 497
Ziyad S, Riordan JD, Cavanaugh AM, et al. (2018) A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224
Tschida BR, Temiz NA, Kuka TP, et al. (2017) Sleeping Beauty insertional mutagenesis in mice identifies drivers of steatosis-associated hepatic tumor. Cancer Research
Riordan JD, Feddersen CR, Tschida BR, et al. (2017) Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma. Hepatology (Baltimore, Md.)
Montero-Conde C, Leandro-Garcia LJ, Chen X, et al. (2017) Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene. Proceedings of the National Academy of Sciences of the United States of America
Temiz NA, Moriarity BS, Wolf NK, et al. (2015) RNA sequencing of Sleeping Beauty transposon-induced tumors detect transposon-RNA fusions allowing precision analyses of forward genetic cancer screens. Genome Research
Smith RP, Riordan JD, Feddersen CR, et al. (2015) A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition. Human Gene Therapy. 26: 377-85
Riordan JD, Drury LJ, Smith RP, et al. (2014) Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens. Bmc Genomics. 15: 1150
Lim L, Balakrishnan A, Huskey N, et al. (2014) MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology (Baltimore, Md.). 59: 202-15
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