Gerrie P. Farman, Ph.D.

Affiliations: 
2004 Illinois Institute of Technology, Chicago, IL, United States 
Area:
General Biophysics, Animal Physiology Biology
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"Gerrie Farman"

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Thomas C. Irving grad student 2004 Illinois Institute of Technology
 (Structural basis of calcium sensitivity in striated muscle.)
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Publications

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Larrinaga TM, Farman GP, Mayfield RM, et al. (2024) Lmod2 is necessary for effective skeletal muscle contraction. Science Advances. 10: eadk1890
Farman GP, Rynkiewicz MJ, Orzechowski M, et al. (2018) HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments. Archives of Biochemistry and Biophysics
Achal M, Trujillo AS, Melkani GC, et al. (2016) A restrictive cardiomyopathy mutation in an invariant proline at the myosin head/rod junction enhances head flexibility and function, yielding muscle defects in Drosophila. Journal of Molecular Biology
Ait-Mou Y, Hsu K, Farman GP, et al. (2016) Titin strain contributes to the Frank-Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins. Proceedings of the National Academy of Sciences of the United States of America
Farman GP, Rynkiewicz M, Orzechowski M, et al. (2016) Cardiomyopathy Linked Mutations in Alpha Tropomyosin Influence Blocked State Stability but not Myosin Strong Binding Biophysical Journal. 110: 124a-125a
Farman GP, Orzechowski M, Fischer S, et al. (2015) Serine 61 Phosphorylation Rescues Cardiomyopathic Effects of Tropomyosin Mutation Biophysical Journal. 108: 446a-447a
Farman GP, Muthu P, Kazmierczak K, et al. (2014) Impact of familial hypertrophic cardiomyopathy-linked mutations in the NH2 terminus of the RLC on β-myosin cross-bridge mechanics. Journal of Applied Physiology (Bethesda, Md. : 1985). 117: 1471-7
Orzechowski M, Fischer S, Moore JR, et al. (2014) Energy landscapes reveal the myopathic effects of tropomyosin mutations. Archives of Biochemistry and Biophysics. 564: 89-99
Huang W, Liang J, Kazmierczak K, et al. (2014) Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice. Journal of Molecular and Cellular Cardiology. 74: 318-29
Farman GP, Moore JR. (2014) Impact of Regulatory Light Chain Phosphorylation on the Stiffness of α and β Myosin Biophysical Journal. 106: 563a
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