John M. Velkey, Ph.D.

2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Anatomy Biology, Cell Biology
"John Velkey"


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Kathy S. O'Shea grad student 2005 University of Michigan
 (Lineage differentiation of embryonic stem cells.)
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Velkey JM, O'Shea KS. (2013) Expression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expression. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 230-53
Purcell EK, Yang A, Liu L, et al. (2013) BDNF profoundly and specifically increases KCNQ4 expression in neurons derived from embryonic stem cells. Stem Cell Research. 10: 29-35
Purcell EK, Naim Y, Yang A, et al. (2012) Combining topographical and genetic cues to promote neuronal fate specification in stem cells. Biomacromolecules. 13: 3427-38
Hill GW, Purcell EK, Liu L, et al. (2012) Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1. Stem Cells and Development. 21: 2827-37
Lunn JS, Pacut C, Stern E, et al. (2012) Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors. Neurobiology of Disease. 46: 59-68
Reyes JH, O'Shea KS, Wys NL, et al. (2008) Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12622-31
Rodriguez RT, Velkey JM, Lutzko C, et al. (2007) Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types. Experimental Biology and Medicine (Maywood, N.J.). 232: 1368-80
Velkey JM, Slawny NA, Gratsch TE, et al. (2006) Gene silencing using RNA interference in embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 329: 233-61
Velkey JM, O'Shea KS. (2003) Oct4 RNA interference induces trophectoderm differentiation in mouse embryonic stem cells. Genesis (New York, N.Y. : 2000). 37: 18-24
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