Lee M Greenberger

Affiliations: 
1979-1984 Anatomy Emory University School of Medicine, Atlanta, GA, United States 
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"Lee Greenberger"
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Cook RS, Garrett JT, Sánchez V, et al. (2011) ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis Cancer Research. 71: 3941-3951
Sapra P, Kraft P, Mehlig M, et al. (2009) Marked therapeutic efficacy of a novel polyethylene glycol-SN38 conjugate, EZN-2208, in xenograft models of B-cell non-Hodgkin's lymphoma. Haematologica. 94: 1456-9
Zhao H, Rubio B, Sapra P, et al. (2008) Novel prodrugs of SN38 using multiarm poly(ethylene glycol) linkers. Bioconjugate Chemistry. 19: 849-59
Sapra P, Zhao H, Mehlig M, et al. (2008) Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1888-96
Sampath D, Greenberger LM, Beyer C, et al. (2006) Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3459-69
Zask A, Birnberg G, Cheung K, et al. (2004) Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286). Journal of Medicinal Chemistry. 47: 4774-86
Zask A, Birnberg G, Cheung K, et al. (2004) D-piece modifications of the hemiasterlin analog HTI-286 produce potent tubulin inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 4353-8
Niu C, Smith D, Zask A, et al. (2004) Tubulin inhibitors. Synthesis and biological activity of HTI-286 analogs with B-segment heterosubstituents. Bioorganic & Medicinal Chemistry Letters. 14: 4329-32
Wissner A, Hamann PR, Nilakantan R, et al. (2004) Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles. Bioorganic & Medicinal Chemistry Letters. 14: 1411-6
Wissner A, Brawner Floyd MB, Rabindran SK, et al. (2002) Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents. Bioorganic & Medicinal Chemistry Letters. 12: 2893-7
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