Shawn C. Burgess, Ph.D. - Publications

Affiliations: 
1995-2000 Chemistry University of Texas at Dallas, Richardson, TX, United States 
 2000- Center for Human Nutrition and Department of Pharmacology University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States 

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, ... ... Burgess SC, et al. Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability. Cell Metabolism. PMID 38447582 DOI: 10.1016/j.cmet.2024.02.004  0.366
2023 Yiew NKH, Deja S, Ferguson D, Cho K, Jarasvaraparn C, Jacome-Sosa M, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN. Effects of hepatic mitochondrial pyruvate carrier deficiency on lipogenesis and gluconeogenesis in mice. Iscience. 26: 108196. PMID 37942005 DOI: 10.1016/j.isci.2023.108196  0.439
2023 Fu X, Fletcher JA, Deja S, Inigo-Vollmer M, Burgess SC, Browning JD. Persistent fasting lipogenesis links impaired ketogenesis with citrate synthesis in humans with non-alcoholic fatty liver. The Journal of Clinical Investigation. PMID 36928190 DOI: 10.1172/JCI167442  0.303
2023 Yiew NKH, Ferguson D, Cho K, Deja S, Jarasvaraparn C, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN. Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice. Biorxiv : the Preprint Server For Biology. PMID 36824879 DOI: 10.1101/2023.02.17.528992  0.456
2022 Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, ... Burgess SC, et al. Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. Cell Reports. 39: 110733. PMID 35476997 DOI: 10.1016/j.celrep.2022.110733  0.367
2020 Deja S, Duarte J, Fletcher JA, Kucejova B, Fu X, Vale G, Young J, Browning J, Burgess SC. 368-OR: Activation of Hepatic Gluconeogenesis Is Required to Suppress DNL and Stimulate Ketogenesis during Fasting Diabetes. 69. DOI: 10.2337/Db20-368-Or  0.523
2020 Deja S, Fletcher JA, Kucejova B, Fu X, Kim C, Browning J, Horton JD, Burgess SC. 204-OR: Inhibition of Hepatic ACC on a High-Fat Diet Results in Hyperglycemia and Hepatomegaly Due to Excess Energy Generation Diabetes. 69. DOI: 10.2337/Db20-204-Or  0.354
2020 Inigo MMR, Deja S, Kucejova B, Fletcher JA, Fu X, Burgess SC. 1809-P: Liver Pyruvate Carboxylase Knockout Mice Suggest Noncanonical Sources of Acetyl-CoA for Hepatic Lipid Synthesis Diabetes. 69. DOI: 10.2337/Db20-1809-P  0.403
2020 Kucejova B, Deja S, Duarte J, Fu X, Burgess SC. 1721-P: In Vivo Effect of Perturbations in Hepatic Insulin Signaling on the Synthesis and Export of De Novo Synthesized Fatty Acids and Triglycerides Diabetes. 69. DOI: 10.2337/Db20-1721-P  0.513
2019 Deja S, Fu X, Fletcher JA, Kucejova B, Browning JD, Young JD, Burgess SC. Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. Metabolic Engineering. PMID 31891762 DOI: 10.1016/J.Ymben.2019.12.005  0.414
2019 Fletcher JA, Deja S, Satapati S, Fu X, Burgess SC, Browning JD. Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver. Jci Insight. 5. PMID 31012869 DOI: 10.1172/Jci.Insight.127737  0.796
2019 Cappel DA, Deja S, Duarte JAG, Kucejova B, Iñigo M, Fletcher JA, Fu X, Berglund ED, Liu T, Elmquist JK, Hammer S, Mishra P, Browning JD, Burgess SC. Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver. Cell Metabolism. PMID 31006591 DOI: 10.1016/J.Cmet.2019.03.014  0.65
2019 Lutkewitte AJ, Burgess SC, Finck BN. Fatty Acid Desaturation Gets a NAD Reputation. Cell Metabolism. 29: 790-792. PMID 30943390 DOI: 10.1016/J.Cmet.2019.03.007  0.306
2019 Fu X, Deja S, Kucejova B, Duarte JAG, McDonald JG, Burgess SC. Targeted Determination of Tissue Energy Status by LC-MS/MS. Analytical Chemistry. PMID 30938977 DOI: 10.1021/Acs.Analchem.9B00217  0.324
2018 Wu CY, Satapati S, Gui W, Wynn RM, Sharma G, Lou M, Qi X, Burgess SC, Malloy C, Khemtong C, Sherry AD, Chuang D, Merritt ME. A Novel Inhibitor of Pyruvate Dehydrogenase Kinase Stimulates Myocardial Carbohydrate Oxidation in Diet-Induced Obesity. The Journal of Biological Chemistry. PMID 29739849 DOI: 10.1074/Jbc.Ra118.002838  0.8
2018 Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JAG, Fu X, Browning JD, Magnuson MA, Burgess SC. Cytosolic Phosphoenolpyruvate Carboxykinase as a Cataplerotic Pathway in the Small Intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29631378 DOI: 10.1152/Ajpgi.00039.2018  0.404
2018 Pop LM, Mari A, Zhao TJ, Mitchell L, Burgess S, Li X, Adams-Huet B, Lingvay I. Roux-en-Y Gastric Bypass Compared to Equivalent Diet Restriction: Mechanistic Insights into Diabetes Remission. Diabetes, Obesity & Metabolism. PMID 29532631 DOI: 10.1111/Dom.13287  0.334
2018 FLETCHER JA, DEJA S, BURGESS SC, BROWNING J. Effects of NAFLD on Acetyl-CoA Partitioning and Ketone Kinetics in Response to a 24-Hour Fast Diabetes. 67: 47-OR. DOI: 10.2337/Db18-47-Or  0.483
2018 CAPPEL D, DEJA S, FU X, BURGESS SC. Pyruvate Carboxylase Is Required for Hepatic Gluconeogenesis and TCA Cycle Function Diabetes. 67: 1882-P. DOI: 10.2337/Db18-1882-P  0.537
2018 DEJA S, FLETCHER JA, KUCEJOVA B, FU X, YOUNG J, BURGESS SC. Simultaneous2H and13C Metabolic Flux Analysis of Liver Metabolism Using NMR and GC-MS—Methods Validation and New Applications Diabetes. 67: 1876-P. DOI: 10.2337/Db18-1876-P  0.425
2017 Rauckhorst AJ, Gray LR, Sheldon RD, Fu X, Pewa AD, Feddersen CR, Dupuy AJ, Gibson-Corley KN, Cox JE, Burgess SC, Taylor EB. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity. Molecular Metabolism. 6: 1468-1479. PMID 29107293 DOI: 10.1016/J.Molmet.2017.09.002  0.427
2017 Lan T, Morgan DA, Rahmouni K, Sonoda J, Fu X, Burgess SC, Holland WL, Kliewer SA, Mangelsdorf DJ. FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia. Cell Metabolism. PMID 28988823 DOI: 10.1016/J.Cmet.2017.09.005  0.355
2017 Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME. The NQO1 bioactivatable drug, β-Lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism. The Journal of Biological Chemistry. PMID 28916726 DOI: 10.1074/Jbc.M117.813923  0.311
2017 Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Ruddy M, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD. Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. Cell Metabolism. 26: 576. PMID 28877461 DOI: 10.1016/J.Cmet.2017.08.011  0.356
2017 Kim CW, Addy C, Kusunoki J, Anderson NN, Deja S, Fu X, Burgess SC, Li C, Chakravarthy M, Previs S, Milstein S, Fitzgerald K, Kelley DE, Horton JD. Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. Cell Metabolism. 26: 394-406.e6. PMID 28768177 DOI: 10.1016/J.Cmet.2017.07.009  0.455
2017 Morris EM, McCoin CS, Allen JA, Gastecki ML, Koch LG, Britton SL, Fletcher JA, Fu X, Ding WX, Burgess SC, Rector RS, Thyfault JP. Aerobic capacity mediates susceptibility for the transition from steatosis to steatohepatitis. The Journal of Physiology. PMID 28504310 DOI: 10.1113/Jp274281  0.394
2017 Ragavan M, Kirpich A, Fu X, Burgess SC, McIntyre LM, Merritt ME. A Comprehensive Analysis of Myocardial Substrate Preference Emphasizes the Need For a Synchronized Fluxomic/Metabolomic Research Design. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00016.2017. PMID 28411229 DOI: 10.1152/Ajpheart.00016.2017  0.396
2016 Semakova J, Hyroššová P, Méndez-Lucas A, Cutz E, Bermudez J, Burgess S, Alcántara S, Perales JC. PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1 (del/del) mice, unmasking role in non-gluconeogenic tissues. Journal of Physiology and Biochemistry. PMID 27785616 DOI: 10.1007/S13105-016-0528-Y  0.417
2016 Morris EM, Meers GM, Koch LG, Britton SL, Fletcher JA, Shankar K, Fu X, Burgess SC, Ibdah JA, Rector RS, Thyfault JP. Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high fat diet induced hepatic steatosis. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00178.2016. PMID 27600823 DOI: 10.1152/Ajpendo.00178.2016  0.452
2016 Kucejova B, Duarte J, Satapati S, Fu X, Ilkayeva O, Newgard CB, Brugarolas J, Burgess SC. Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity. Cell Reports. PMID 27346353 DOI: 10.1016/J.Celrep.2016.06.006  0.789
2016 Satapati S, Kucejova B, Duarte JA, Fletcher JA, Reynolds L, Sunny NE, He T, Nair LA, Livingston KA, Fu X, Merritt ME, Sherry AD, Malloy CR, Shelton JM, Lambert J, ... ... Burgess SC, et al. Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. The Journal of Clinical Investigation. 126: 1605. PMID 27035816 DOI: 10.1172/Jci86695  0.8
2016 Amoasii L, Holland W, Sanchez-Ortiz E, Baskin KK, Pearson M, Burgess SC, Nelson BR, Bassel-Duby R, Olson EN. A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism. Genes & Development. 30: 434-46. PMID 26883362 DOI: 10.1101/Gad.273128.115  0.558
2015 Satapati S, Kucejova B, Duarte JA, Fletcher JA, Reynolds L, Sunny NE, He T, Nair LA, Livingston K, Fu X, Merritt ME, Sherry AD, Malloy CR, Shelton JM, Lambert J, ... ... Burgess SC, et al. Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. The Journal of Clinical Investigation. PMID 26571396 DOI: 10.1172/Jci82204  0.81
2015 Moreno KX, Moore CL, Burgess SC, Sherry AD, Malloy CR, Merritt ME. Production of hyperpolarized (13)CO2 from [1-(13)C]pyruvate in perfused liver does reflect total anaplerosis but is not a reliable biomarker of glucose production. Metabolomics : Official Journal of the Metabolomic Society. 11: 1144-1156. PMID 26543443 DOI: 10.1007/S11306-014-0768-1  0.724
2015 Gray LR, Sultana MR, Rauckhorst AJ, Oonthonpan L, Tompkins SC, Sharma A, Fu X, Miao R, Pewa AD, Brown KS, Lane EE, Dohlman A, Zepeda-Orozco D, Xie J, Rutter J, ... ... Burgess SC, et al. Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis. Cell Metabolism. PMID 26344103 DOI: 10.1016/J.Cmet.2015.07.027  0.734
2015 McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN. Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling. Cell Metabolism. 22: 682-94. PMID 26344101 DOI: 10.1016/J.Cmet.2015.07.028  0.479
2015 Buescher JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H, Clish CB, DeBerardinis RJ, Feron O, Frezza C, Ghesquiere B, Gottlieb E, Hiller K, Jones RG, Kamphorst JJ, Kibbey RG, et al. A roadmap for interpreting (13)C metabolite labeling patterns from cells. Current Opinion in Biotechnology. 34: 189-201. PMID 25731751 DOI: 10.1016/J.Copbio.2015.02.003  0.589
2015 Burgess SC, Merritt ME, Jones JG, Browning JD, Sherry AD, Malloy CR. Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate. Nature Medicine. 21: 108-9. PMID 25654596 DOI: 10.1038/Nm.3789  0.666
2015 Moreno KX, Moore CL, Burgess SC, Sherry AD, Malloy CR, Merritt ME. Production of hyperpolarized 13CO2 from [1-13C]pyruvate in perfused liver does reflect total anaplerosis but is not a reliable biomarker of glucose production Metabolomics. DOI: 10.1007/s11306-014-0768-1  0.523
2014 Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN. MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver. Embo Molecular Medicine. 6: 1610-21. PMID 25422356 DOI: 10.15252/Emmm.201404218  0.791
2014 Moreno KX, Satapati S, DeBerardinis RJ, Burgess SC, Malloy CR, Merritt ME. Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone. The Journal of Biological Chemistry. 289: 35859-67. PMID 25352600 DOI: 10.1074/Jbc.M114.613265  0.809
2014 Purmal C, Kucejova B, Sherry AD, Burgess SC, Malloy CR, Merritt ME. Propionate stimulates pyruvate oxidation in the presence of acetate. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1134-41. PMID 25320331 DOI: 10.1152/Ajpheart.00407.2014  0.704
2014 Duarte JA, Carvalho F, Pearson M, Horton JD, Browning JD, Jones JG, Burgess SC. A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice. Journal of Lipid Research. 55: 2541-53. PMID 25271296 DOI: 10.1194/Jlr.M052308  0.406
2014 Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN. Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Reports. 7: 2042-53. PMID 24910426 DOI: 10.1016/J.Celrep.2014.05.017  0.475
2013 Wan M, Leavens KF, Hunter RW, Koren S, von Wilamowitz-Moellendorff A, Lu M, Satapati S, Chu Q, Sakamoto K, Burgess SC, Birnbaum MJ. A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition. Cell Metabolism. 18: 99-105. PMID 23823480 DOI: 10.1016/J.Cmet.2013.06.001  0.791
2013 Méndez-Lucas A, Duarte JA, Sunny NE, Satapati S, He T, Fu X, Bermúdez J, Burgess SC, Perales JC. PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis. Journal of Hepatology. 59: 105-13. PMID 23466304 DOI: 10.1016/J.Jhep.2013.02.020  0.78
2013 Ramos-Roman MA, Burgess SC, Browning JD. Metabolomics, stable isotopes, and A-β+ ketosis-prone diabetes. Diabetes. 62: 682-4. PMID 23431008 DOI: 10.2337/Db12-1347  0.366
2013 Potthoff MJ, Potts A, He T, Duarte JA, Taussig R, Mangelsdorf DJ, Kliewer SA, Burgess SC. Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G371-80. PMID 23257920 DOI: 10.1152/Ajpgi.00400.2012  0.719
2013 Zechner JF, Mirshahi UL, Satapati S, Berglund ED, Rossi J, Scott MM, Still CD, Gerhard GS, Burgess SC, Mirshahi T, Aguirre V. Weight-independent effects of roux-en-Y gastric bypass on glucose homeostasis via melanocortin-4 receptors in mice and humans. Gastroenterology. 144: 580-590.e7. PMID 23159449 DOI: 10.1053/J.Gastro.2012.11.022  0.739
2012 Chambers KT, Chen Z, Crawford PA, Fu X, Burgess SC, Lai L, Leone TC, Kelly DP, Finck BN. Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding. Plos One. 7: e52645. PMID 23285128 DOI: 10.1371/Journal.Pone.0052645  0.492
2012 Browning JD, Burgess SC. Use of (2)H(2)O for estimating rates of gluconeogenesis: determination and correction of error due to transaldolase exchange. American Journal of Physiology. Endocrinology and Metabolism. 303: E1304-12. PMID 23032685 DOI: 10.1152/Ajpendo.00306.2012  0.384
2012 Lee Y, Berglund ED, Wang MY, Fu X, Yu X, Charron MJ, Burgess SC, Unger RH. Metabolic manifestations of insulin deficiency do not occur without glucagon action. Proceedings of the National Academy of Sciences of the United States of America. 109: 14972-6. PMID 22891336 DOI: 10.1073/Pnas.1205983109  0.418
2012 Satapati S, Sunny NE, Kucejova B, Fu X, He TT, Méndez-Lucas A, Shelton JM, Perales JC, Browning JD, Burgess SC. Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver. Journal of Lipid Research. 53: 1080-92. PMID 22493093 DOI: 10.1194/Jlr.M023382  0.786
2012 Browning JD, Baxter J, Satapati S, Burgess SC. The effect of short-term fasting on liver and skeletal muscle lipid, glucose, and energy metabolism in healthy women and men. Journal of Lipid Research. 53: 577-86. PMID 22140269 DOI: 10.1194/Jlr.P020867  0.75
2011 Sunny NE, Parks EJ, Browning JD, Burgess SC. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. Cell Metabolism. 14: 804-10. PMID 22152305 DOI: 10.1016/J.Cmet.2011.11.004  0.494
2011 Merritt ME, Harrison C, Sherry AD, Malloy CR, Burgess SC. Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance. Proceedings of the National Academy of Sciences of the United States of America. 108: 19084-9. PMID 22065779 DOI: 10.1073/Pnas.1111247108  0.768
2011 Lubag AJ, De Leon-Rodriguez LM, Burgess SC, Sherry AD. Noninvasive MRI of β-cell function using a Zn2+-responsive contrast agent. Proceedings of the National Academy of Sciences of the United States of America. 108: 18400-5. PMID 22025712 DOI: 10.1073/Pnas.1109649108  0.794
2011 Potthoff MJ, Boney-Montoya J, Choi M, He T, Sunny NE, Satapati S, Suino-Powell K, Xu HE, Gerard RD, Finck BN, Burgess SC, Mangelsdorf DJ, Kliewer SA. FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway. Cell Metabolism. 13: 729-38. PMID 21641554 DOI: 10.1016/J.Cmet.2011.03.019  0.812
2011 Browning JD, Baker JA, Rogers T, Davis J, Satapati S, Burgess SC. Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction. The American Journal of Clinical Nutrition. 93: 1048-52. PMID 21367948 DOI: 10.3945/Ajcn.110.007674  0.745
2011 Kucejova B, Sunny NE, Nguyen AD, Hallac R, Fu X, Peña-Llopis S, Mason RP, Deberardinis RJ, Xie XJ, Debose-Boyd R, Kodibagkar VD, Burgess SC, Brugarolas J. Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death. Oncogene. 30: 2147-60. PMID 21217781 DOI: 10.1038/onc.2010.587  0.37
2010 Sunny NE, Satapati S, Fu X, He T, Mehdibeigi R, Spring-Robinson C, Duarte J, Potthoff MJ, Browning JD, Burgess SC. Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet. American Journal of Physiology. Endocrinology and Metabolism. 298: E1226-35. PMID 20233938 DOI: 10.1152/Ajpendo.00033.2010  0.811
2009 Potthoff MJ, Inagaki T, Satapati S, Ding X, He T, Goetz R, Mohammadi M, Finck BN, Mangelsdorf DJ, Kliewer SA, Burgess SC. FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proceedings of the National Academy of Sciences of the United States of America. 106: 10853-8. PMID 19541642 DOI: 10.1073/Pnas.0904187106  0.803
2009 Kley S, Hoenig M, Glushka J, Jin ES, Burgess SC, Waldron M, Jordan ET, Prestegard JH, Ferguson DC, Wu S, Olson DE. The impact of obesity, sex, and diet on hepatic glucose production in cats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R936-43. PMID 19193946 DOI: 10.1152/Ajpregu.90771.2008  0.655
2009 Newgard CB, Stevens RD, Wenner BR, Burgess SC, Ilkayeva O, Muehlbauer MJ, Sherry AD, Bain JR. Comprehensive Metabolic Analysis for Understanding of Disease Mechanisms Genomic and Personalized Medicine, Two-Vol Set. 180-192. DOI: 10.1016/B978-0-12-369420-1.00015-9  0.488
2008 Browning JD, Weis B, Davis J, Satapati S, Merritt M, Malloy CR, Burgess SC. Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction. Hepatology (Baltimore, Md.). 48: 1487-96. PMID 18925642 DOI: 10.1002/Hep.22504  0.823
2008 Ronnebaum SM, Jensen MV, Hohmeier HE, Burgess SC, Zhou YP, Qian S, MacNeil D, Howard A, Thornberry N, Ilkayeva O, Lu D, Sherry AD, Newgard CB. Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets. The Journal of Biological Chemistry. 283: 28909-17. PMID 18755687 DOI: 10.1074/Jbc.M804665200  0.58
2008 Jensen MV, Joseph JW, Ronnebaum SM, Burgess SC, Sherry AD, Newgard CB. Metabolic cycling in control of glucose-stimulated insulin secretion. American Journal of Physiology. Endocrinology and Metabolism. 295: E1287-97. PMID 18728221 DOI: 10.1152/Ajpendo.90604.2008  0.577
2008 Burgess SC, Chandramouli V, Browning JD, Schumann WC, Previs SF. Complicating factors in the application of the "average method" for determining the contribution of gluconeogenesis. Journal of Applied Physiology (Bethesda, Md. : 1985). 104: 1852-3; author reply. PMID 18523054 DOI: 10.1152/Japplphysiol.90406.2008  0.341
2008 Satapati S, He T, Inagaki T, Potthoff M, Merritt ME, Esser V, Mangelsdorf DJ, Kliewer SA, Browning JD, Burgess SC. Partial resistance to peroxisome proliferator-activated receptor-alpha agonists in ZDF rats is associated with defective hepatic mitochondrial metabolism. Diabetes. 57: 2012-21. PMID 18469201 DOI: 10.2337/Db08-0226  0.814
2008 Ronnebaum SM, Joseph JW, Ilkayeva O, Burgess SC, Lu D, Becker TC, Sherry AD, Newgard CB. Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism. The Journal of Biological Chemistry. 283: 14248-56. PMID 18381287 DOI: 10.1074/Jbc.M800119200  0.608
2008 Zhao G, Jeoung NH, Burgess SC, Rosaaen-Stowe KA, Inagaki T, Latif S, Shelton JM, McAnally J, Bassel-Duby R, Harris RA, Richardson JA, Kliewer SA. Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 294: H936-43. PMID 18083902 DOI: 10.1152/Ajpheart.00870.2007  0.412
2008 Burgess SC, Iizuka K, Jeoung NH, Harris RA, Kashiwaya Y, Veech RL, Kitazume T, Uyeda K. Carbohydrate-response element-binding protein deletion alters substrate utilization producing an energy-deficient liver. The Journal of Biological Chemistry. 283: 1670-8. PMID 18042547 DOI: 10.1074/Jbc.M706540200  0.472
2008 Bock G, Schumann WC, Basu R, Burgess SC, Yan Z, Chandramouli V, Rizza RA, Landau BR. Evidence that processes other than gluconeogenesis may influence the ratio of deuterium on the fifth and third carbons of glucose: implications for the use of 2H2O to measure gluconeogenesis in humans. Diabetes. 57: 50-5. PMID 17934142 DOI: 10.2337/Db07-0694  0.394
2008 Chevalier S, Morais JA, Marliss EB, Burgess SC, Gougeon R. Greater Gluconeogenesis and Abnormal Hepatic Autoregulation in Type 2 Diabetes (T2DM) are Associated with Insulin Resistance of Protein Anabolism. Canadian Journal of Diabetes. 32: 304. DOI: 10.1016/S1499-2671(08)24023-2  0.35
2007 Joseph JW, Odegaard ML, Ronnebaum SM, Burgess SC, Muehlbauer J, Sherry AD, Newgard CB. Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion. The Journal of Biological Chemistry. 282: 31592-600. PMID 17823126 DOI: 10.1074/Jbc.M706080200  0.56
2007 Rogoff D, Ryder JW, Black K, Yan Z, Burgess SC, McMillan DR, White PC. Abnormalities of glucose homeostasis and the hypothalamic-pituitary-adrenal axis in mice lacking hexose-6-phosphate dehydrogenase. Endocrinology. 148: 5072-80. PMID 17656460 DOI: 10.1210/En.2007-0593  0.435
2007 Inagaki T, Dutchak P, Zhao G, Ding X, Gautron L, Parameswara V, Li Y, Goetz R, Mohammadi M, Esser V, Elmquist JK, Gerard RD, Burgess SC, Hammer RE, Mangelsdorf DJ, et al. Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metabolism. 5: 415-25. PMID 17550777 DOI: 10.1016/J.Cmet.2007.05.003  0.574
2007 Burgess SC, He T, Yan Z, Lindner J, Sherry AD, Malloy CR, Browning JD, Magnuson MA. Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver. Cell Metabolism. 5: 313-20. PMID 17403375 DOI: 10.1016/J.Cmet.2007.03.004  0.738
2006 Mendes AC, Caldeira MM, Silva C, Burgess SC, Merritt ME, Gomes F, Barosa C, Delgado TC, Franco F, Monteiro P, Providencia L, Jones JG. Hepatic UDP-glucose 13C isotopomers from [U-13C]glucose: a simple analysis by 13C NMR of urinary menthol glucuronide. Magnetic Resonance in Medicine. 56: 1121-5. PMID 17036288 DOI: 10.1002/Mrm.21057  0.429
2006 Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion. The Journal of Biological Chemistry. 281: 30593-602. PMID 16912049 DOI: 10.1074/Jbc.M511908200  0.603
2006 Stowe KA, Burgess SC, Merritt M, Sherry AD, Malloy CR. Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy. Febs Letters. 580: 4282-7. PMID 16831433 DOI: 10.1016/J.Febslet.2006.06.068  0.672
2006 Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion. The Journal of Biological Chemistry. 281: 22342-51. PMID 16740637 DOI: 10.1074/Jbc.M604350200  0.54
2006 Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN. Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice. The Journal of Biological Chemistry. 281: 19000-8. PMID 16670093 DOI: 10.1074/Jbc.M600050200  0.698
2006 Chevalier S, Burgess SC, Malloy CR, Gougeon R, Marliss EB, Morais JA. The greater contribution of gluconeogenesis to glucose production in obesity is related to increased whole-body protein catabolism. Diabetes. 55: 675-81. PMID 16505230 DOI: 10.2337/Diabetes.55.03.06.Db05-1117  0.658
2006 Hausler N, Browning J, Merritt M, Storey C, Milde A, Jeffrey FM, Sherry AD, Malloy CR, Burgess SC. Effects of insulin and cytosolic redox state on glucose production pathways in the isolated perfused mouse liver measured by integrated 2H and 13C NMR. The Biochemical Journal. 394: 465-73. PMID 16288601 DOI: 10.1042/Bj20051174  0.768
2005 Peltz M, Hamilton TT, He TT, Adams GA, Koshy S, Burgess SC, Chao RY, Jessen ME, Meyer DM. Lung preservation solution substrate composition affects rat lung oxidative metabolism during hypothermic storage. Respiratory Physiology & Neurobiology. 148: 275-83. PMID 16143284 DOI: 10.1016/J.Resp.2005.02.010  0.357
2005 Jin ES, Jones JG, Burgess SC, Merritt ME, Sherry AD, Malloy CR. Comparison of [3,4-13C2]glucose to [6,6-2H2]glucose as a tracer for glucose turnover by nuclear magnetic resonance. Magnetic Resonance in Medicine. 53: 1479-83. PMID 15906303 DOI: 10.1002/Mrm.20496  0.781
2005 Burgess SC, Jeffrey FM, Storey C, Milde A, Hausler N, Merritt ME, Mulder H, Holm C, Sherry AD, Malloy CR. Effect of murine strain on metabolic pathways of glucose production after brief or prolonged fasting. American Journal of Physiology. Endocrinology and Metabolism. 289: E53-61. PMID 15797985 DOI: 10.1152/Ajpendo.00601.2004  0.683
2005 Yu X, Burgess SC, Ge H, Wong KK, Nassem RH, Garry DJ, Sherry AD, Malloy CR, Berger JP, Li C. Inhibition of cardiac lipoprotein utilization by transgenic overexpression of Angptl4 in the heart. Proceedings of the National Academy of Sciences of the United States of America. 102: 1767-72. PMID 15659544 DOI: 10.1073/Pnas.0409564102  0.643
2005 Jin ES, Burgess SC, Merritt ME, Sherry AD, Malloy CR. Differing mechanisms of hepatic glucose overproduction in triiodothyronine-treated rats vs. Zucker diabetic fatty rats by NMR analysis of plasma glucose. American Journal of Physiology. Endocrinology and Metabolism. 288: E654-62. PMID 15562253 DOI: 10.1152/Ajpendo.00365.2004  0.793
2004 Burgess SC, Hausler N, Merritt M, Jeffrey FM, Storey C, Milde A, Koshy S, Lindner J, Magnuson MA, Malloy CR, Sherry AD. Impaired tricarboxylic acid cycle activity in mouse livers lacking cytosolic phosphoenolpyruvate carboxykinase. The Journal of Biological Chemistry. 279: 48941-9. PMID 15347677 DOI: 10.1074/Jbc.M407120200  0.768
2004 Newgard CB, Hohmeier HE, Lu D, Jensen MV, Tran VV, Chen G, Burgess S, Sherry AD. Understanding of basic mechanisms of beta-cell function and survival: prelude to new diabetes therapies Cell Biochemistry and Biophysics. 40: 159-168. PMID 15289651 DOI: 10.1385/Cbb:40:3:159  0.476
2004 Boucher A, Lu D, Burgess SC, Telemaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD, Newgard CB. Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue. The Journal of Biological Chemistry. 279: 27263-71. PMID 15073188 DOI: 10.1074/Jbc.M401167200  0.611
2004 Weis BC, Margolis D, Burgess SC, Merritt ME, Wise H, Sherry AD, Malloy CR. Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy. Magnetic Resonance in Medicine. 51: 649-54. PMID 15065235 DOI: 10.1002/Mrm.20057  0.695
2004 Jin ES, Jones JG, Merritt M, Burgess SC, Malloy CR, Sherry AD. Glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative. Analytical Biochemistry. 327: 149-55. PMID 15051530 DOI: 10.1016/J.Ab.2003.12.036  0.8
2003 Merritt M, Bretthorst GL, Burgess SC, Sherry AD, Malloy CR. Sources of plasma glucose by automated Bayesian analysis of 2H NMR spectra. Magnetic Resonance in Medicine. 50: 659-63. PMID 14523948 DOI: 10.1002/Mrm.10577  0.7
2003 She P, Burgess SC, Shiota M, Flakoll P, Donahue EP, Malloy CR, Sherry AD, Magnuson MA. Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation. Diabetes. 52: 1649-54. PMID 12829628 DOI: 10.2337/Diabetes.52.7.1649  0.753
2003 Burgess SC, Nuss M, Chandramouli V, Hardin DS, Rice M, Landau BR, Malloy CR, Sherry AD. Analysis of gluconeogenic pathways in vivo by distribution of 2H in plasma glucose: comparison of nuclear magnetic resonance and mass spectrometry. Analytical Biochemistry. 318: 321-4. PMID 12814639 DOI: 10.1016/S0003-2697(03)00158-1  0.662
2003 Jin ES, Uyeda K, Kawaguchi T, Burgess SC, Malloy CR, Sherry AD. Increased hepatic fructose 2,6-bisphosphate after an oral glucose load does not affect gluconeogenesis. The Journal of Biological Chemistry. 278: 28427-33. PMID 12764148 DOI: 10.1074/Jbc.M302134200  0.792
2003 Burgess SC, Weis B, Jones JG, Smith E, Merritt ME, Margolis D, Dean Sherry A, Malloy CR. Noninvasive evaluation of liver metabolism by 2H and 13C NMR isotopomer analysis of human urine. Analytical Biochemistry. 312: 228-34. PMID 12531210 DOI: 10.1016/S0003-2697(02)00465-7  0.663
2002 Zhang S, Michaudet L, Burgess S, Sherry AD. The amide protons of an ytterbium(III) dota tetraamide complex act as efficient antennae for transfer of magnetization to bulk water Angewandte Chemie - International Edition. 41: 1919-1921. PMID 19750633 DOI: 10.1002/1521-3773(20020603)41:11<1919::Aid-Anie1919>3.0.Co;2-Q  0.315
2002 Newgard CB, Lu D, Jensen MV, Schissler J, Boucher A, Burgess S, Sherry AD. Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: Insights gained from a multidisciplinary approach Diabetes. 51: S389-S393. PMID 12475781 DOI: 10.2337/Diabetes.51.2007.S389  0.563
2002 Lu D, Mulder H, Zhao P, Burgess SC, Jensen MV, Kamzolova S, Newgard CB, Sherry AD. 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proceedings of the National Academy of Sciences of the United States of America. 99: 2708-13. PMID 11880625 DOI: 10.1073/Pnas.052005699  0.631
2001 Burgess SC, Babcock EE, Jeffrey FM, Sherry AD, Malloy CR. NMR indirect detection of glutamate to measure citric acid cycle flux in the isolated perfused mouse heart. Febs Letters. 505: 163-7. PMID 11557062 DOI: 10.1016/S0014-5793(01)02799-5  0.47
2001 Zhang S, Kovacs Z, Burgess S, Aime S, Terreno E, Sherry AD. {DOTA-bis(amide)}lanthanide complexes: NMR evidence for differences in water-molecule exchange rates for coordination isomers Chemistry - a European Journal. 7: 288-296. PMID 11205022 DOI: 10.1002/1521-3765(20010105)7:1<288::Aid-Chem288>3.0.Co;2-6  0.411
2001 Burgess SC, Carvalho RA, Merritt ME, Jones JG, Malloy CR, Sherry AD. 13C isotopomer analysis of glutamate by J-resolved heteronuclear single quantum coherence spectroscopy. Analytical Biochemistry. 289: 187-95. PMID 11161312 DOI: 10.1006/Abio.2000.4930  0.493
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