Francesco Cecconi - Publications

Affiliations: 
IRCCS Santa Lucia Foundation and University of Rome Tor Vergata, Italy 
Area:
Neurodevelopment

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Faienza F, Polverino F, Rajendraprasad G, Milletti G, Hu Z, Colella B, Gargano D, Strappazzon F, Rizza S, Vistesen MV, Luo Y, Antonioli M, Cianfanelli V, Ferraina C, Fimia GM, ... ... Cecconi F, et al. AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation. Cellular and Molecular Life Sciences : Cmls. 80: 251. PMID 37584777 DOI: 10.1007/s00018-023-04878-6  0.769
2023 Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Cecconi F, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w  0.7
2023 Frias A, Di Leo L, Antoranz A, Nazerai L, Carretta M, Bodemeyer V, Pagliuca C, Dahl C, Claps G, Mandelli GE, Andhari MD, Pacheco MP, Sauter T, Robert C, Guldberg P, ... ... Cecconi F, et al. Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma. Journal For Immunotherapy of Cancer. 11. PMID 36868570 DOI: 10.1136/jitc-2022-006389  0.682
2023 Pignataro A, Krashia P, De Introna M, Nobili A, Sabetta A, Stabile F, La Barbera L, D'Addario SL, Ventura R, Cecconi F, D'Amelio M, Ammassari-Teule M. Chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the Ambra1+/- mouse model of female autism. Translational Psychiatry. 13: 63. PMID 36804922 DOI: 10.1038/s41398-023-02357-x  0.501
2022 Tiberti M, Di Leo L, Vistesen MV, Kuhre RS, Cecconi F, De Zio D, Papaleo E. The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma. Cell Death & Disease. 13: 872. PMID 36243772 DOI: 10.1038/s41419-022-05318-2  0.651
2021 Maiani E, Milletti G, Cecconi F. The pro-autophagic protein AMBRA1 coordinates cell cycle progression by regulating CCND (cyclin D) stability. Autophagy. 17: 4506-4508. PMID 34657573 DOI: 10.1080/15548627.2021.1985917  0.304
2021 Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, et al. Autophagy in major human diseases. The Embo Journal. e108863. PMID 34459017 DOI: 10.15252/embj.2021108863  0.467
2021 Di Leo L, Bodemeyer V, Bosisio FM, Claps G, Carretta M, Rizza S, Faienza F, Frias A, Khan S, Bordi M, Pacheco MP, Di Martino J, Bravo-Cordero JJ, Daniel CJ, Sears RC, ... ... Cecconi F, et al. Loss of Ambra1 promotes melanoma growth and invasion. Nature Communications. 12: 2550. PMID 33953176 DOI: 10.1038/s41467-021-22772-2  0.683
2021 Carinci M, Testa B, Bordi M, Milletti G, Bonora M, Antonucci L, Ferraina C, Carro M, Kumar M, Ceglie D, Eck F, Nardacci R, le Guerroué F, Petrini S, Soriano ME, ... ... Cecconi F, et al. TFG binds LC3C to regulate ULK1 localization and autophagosome formation. The Embo Journal. e103563. PMID 33932238 DOI: 10.15252/embj.2019103563  0.329
2021 Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, ... ... Cecconi F, et al. AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature. PMID 33854232 DOI: 10.1038/s41586-021-03422-5  0.689
2021 Finetti F, Cassioli C, Cianfanelli V, Zevolini F, Onnis A, Gesualdo M, Brunetti J, Cecconi F, Baldari CT. The Intraflagellar Transport Protein IFT20 Recruits ATG16L1 to Early Endosomes to Promote Autophagosome Formation in T Cells. Frontiers in Cell and Developmental Biology. 9: 634003. PMID 33829015 DOI: 10.3389/fcell.2021.634003  0.321
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Cecconi F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.779
2020 Macchiaiolo M, Buonuomo PS, Mastrogiorgio G, Bordi M, Testa B, Weber G, Bellacchio E, Tartaglia M, Cecconi F, Bartuli A. Very mild isolated intellectual disability caused by adenylosuccinate lyase deficiency: a new phenotype. Molecular Genetics and Metabolism Reports. 23: 100592. PMID 32405461 DOI: 10.1016/j.ymgmr.2020.100592  0.329
2020 Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, Di Daniele A, Caicci F, Caruana I, Soriano ME, Pigazzi M, Locatelli F, Cecconi F, Campello S. JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Cell Death and Differentiation. PMID 32346136 DOI: 10.1038/s41418-020-0540-1  0.464
2020 Bell K, Rosignol I, Sierra-Filardi E, Rodriguez-Muela N, Schmelter C, Cecconi F, Grus F, Boya P. Age related retinal Ganglion cell susceptibility in context of autophagy deficiency. Cell Death Discovery. 6: 21. PMID 32337073 DOI: 10.1038/s41420-020-0257-4  0.374
2020 Meneghetti G, Skobo T, Chrisam M, Fontana CM, Facchinello N, Nazio F, Cecconi F, Bonaldo P, Dalla Valle L. Zebrafish and Silencing Affect Heart Development. Zebrafish. PMID 32320344 DOI: 10.1089/zeb.2020.1860  0.307
2020 Messina F, Cecconi F, Rodolfo C. Do You Remember Mitochondria? Frontiers in Physiology. 11: 271. PMID 32292356 DOI: 10.3389/fphys.2020.00271  0.345
2020 Mandatori S, Pacella I, Marzolla V, Mammi C, Starace D, Padula F, Vitiello L, Armani A, Savoia C, Taurino M, De Zio D, Giampietri C, Piconese S, Cecconi F, Caprio M, et al. Altered Tregs Differentiation and Impaired Autophagy Correlate to Atherosclerotic Disease. Frontiers in Immunology. 11: 350. PMID 32231663 DOI: 10.3389/fimmu.2020.00350  0.742
2020 Cianfanelli V, Cecconi F. Doryphagy: when selective autophagy safeguards centrosome integrity. Molecular & Cellular Oncology. 7: 1719021. PMID 32158930 DOI: 10.1080/23723556.2020.1719021  0.316
2019 Holdgaard SG, Cianfanelli V, Cecconi F. Cloud hunting: doryphagy, a form of selective autophagy that degrades centriolar satellites. Autophagy. 1-3. PMID 31847687 DOI: 10.1080/15548627.2019.1703356  0.399
2019 Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, ... ... Cecconi F, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nature Communications. 10: 4176. PMID 31519908 DOI: 10.1038/S41467-019-12094-9  0.718
2019 Melino G, Cecconi F, Pelicci PG, Wah Mak T, Bernassola F. Emerging roles of HECT-type E3 ubiquitin ligases in autophagy regulation. Molecular Oncology. PMID 31441992 DOI: 10.1002/1878-0261.12567  0.42
2019 Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, Melino G, Cecconi F. HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy. Cell Death and Differentiation. PMID 31434979 DOI: 10.1038/s41418-019-0404-8  0.396
2019 Deretic V, Prossnitz E, Burge M, Campen MJ, Cannon J, Liu KJ, Hall P, Sklar LA, Allers L, Mariscal L, Garcia SA, Baehrecke EH, Behrends C, Cecconi F, Codogno P, et al. Autophagy, Inflammation, and Metabolism (AIM) Center in its second year. Autophagy. PMID 31234750 DOI: 10.1080/15548627.2019.1634444  0.301
2019 Montagna C, Rizza S, Cirotti C, Maiani E, Muscaritoli M, Musarò A, Carrí MT, Ferraro E, Cecconi F, Filomeni G. nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis. Cell Death & Disease. 10: 354. PMID 31043586 DOI: 10.1038/s41419-019-1584-3  0.559
2019 D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, Weber G, Del Bufalo F, Dalla Valle L, Campello S, Locatelli F, Cecconi F. Reversible induction of mitophagy by an optogenetic bimodular system. Nature Communications. 10: 1533. PMID 30948710 DOI: 10.1038/s41467-019-09487-1  0.422
2019 Meneghetti G, Skobo T, Chrisam M, Facchinello N, Fontana CM, Bellesso S, Sabatelli P, Raggi F, Cecconi F, Bonaldo P, Dalla Valle L. The epg5 knockout zebrafish line: a model to study Vici syndrome. Autophagy. PMID 30806141 DOI: 10.1080/15548627.2019.1586247  0.331
2019 Nazio F, Bordi M, Cianfanelli V, Locatelli F, Cecconi F. Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications. Cell Death and Differentiation. PMID 30728463 DOI: 10.1038/s41418-019-0292-y  0.358
2018 Becher J, Simula L, Volpe E, Procaccini C, La Rocca C, D'Acunzo P, Cianfanelli V, Strappazzon F, Caruana I, Nazio F, Weber G, Gigantino V, Botti G, Ciccosanti F, Borsellino G, ... ... Cecconi F, et al. AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis. Developmental Cell. 47: 592-607.e6. PMID 30513302 DOI: 10.1016/J.Devcel.2018.11.010  0.601
2018 Colella B, Faienza F, Carinci M, D'Alessandro G, Catalano M, Santoro A, Cecconi F, Limatola C, Di Bartolomeo S. Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells. Cellular Signalling. 53: 357-364. PMID 30442596 DOI: 10.1016/j.cellsig.2018.10.017  0.628
2018 Russo R, Varano GP, Adornetto A, Nazio F, Tettamanti G, Girardello R, Cianfanelli V, Cavaliere F, Morrone LA, Corasaniti MT, Cecconi F, Bagetta G, Nucci C. Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival. Cell Death & Disease. 9: 981. PMID 30250019 DOI: 10.1038/s41419-018-1044-5  0.381
2018 Di Rita A, Peschiaroli A, D Acunzo P, Strobbe D, Hu Z, Gruber J, Nygaard M, Lambrughi M, Melino G, Papaleo E, Dengjel J, El Alaoui S, Campanella M, Dötsch V, Rogov VV, ... ... Cecconi F, et al. HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα. Nature Communications. 9: 3755. PMID 30217973 DOI: 10.1038/S41467-018-05722-3  0.437
2018 Onnis A, Cianfanelli V, Cassioli C, Samardzic D, Pelicci PG, Cecconi F, Baldari CT. The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II. Autophagy. PMID 30109811 DOI: 10.1080/15548627.2018.1505153  0.438
2018 Di Rita A, D'Acunzo P, Simula L, Campello S, Strappazzon F, Cecconi F. AMBRA1-Mediated Mitophagy Counteracts Oxidative Stress and Apoptosis Induced by Neurotoxicity in Human Neuroblastoma SH-SY5Y Cells. Frontiers in Cellular Neuroscience. 12: 92. PMID 29755319 DOI: 10.3389/fncel.2018.00092  0.425
2018 Rizza S, Cardaci S, Montagna C, Di Giacomo G, De Zio D, Bordi M, Maiani E, Campello S, Borreca A, Puca AA, Stamler JS, Cecconi F, Filomeni G. -nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581312 DOI: 10.1073/Pnas.1722452115  0.726
2018 Nobili A, Krashia P, Cordella A, La Barbera L, Dell'Acqua MC, Caruso A, Pignataro A, Marino R, Sciarra F, Biamonte F, Scattoni ML, Ammassari-Teule M, Cecconi F, Berretta N, Keller F, et al. Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders. Molecular Neurobiology. PMID 29488136 DOI: 10.1007/S12035-018-0911-5  0.573
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Cecconi F, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4  0.586
2017 Nazio F, Carinci M, Cecconi F. ULK1 ubiquitylation is regulated by phosphorylation on its carboxy terminus. Cell Cycle (Georgetown, Tex.). 0. PMID 28820317 DOI: 10.1080/15384101.2017.1361063  0.43
2017 Rodolfo C, Campello S, Cecconi F. Mitophagy in neurodegenerative diseases. Neurochemistry International. PMID 28797885 DOI: 10.1016/j.neuint.2017.08.004  0.322
2017 Galluzzi L, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cecconi F, Choi AM, Chu CT, Codogno P, Colombo MI, Cuervo AM, Debnath J, Deretic V, Dikic I, Eskelinen EL, et al. Molecular definitions of autophagy and related processes. The Embo Journal. PMID 28596378 DOI: 10.15252/Embj.201796697  0.535
2017 Mathiassen SG, De Zio D, Cecconi F. Autophagy and the Cell Cycle: A Complex Landscape. Frontiers in Oncology. 7: 51. PMID 28409123 DOI: 10.3389/fonc.2017.00051  0.765
2017 Schoenherr C, Byron A, Sandilands E, Paliashvili K, Baillie GS, Valacca C, Cecconi F, Serrels B, Frame MC. Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks. Elife. 6. PMID 28362576 DOI: 10.7554/eLife.23172  0.366
2017 Nazio F, Cecconi F. Autophagy up and down by outsmarting the incredible ULK. Autophagy. 1-2. PMID 28282264 DOI: 10.1080/15548627.2017.1285473  0.424
2017 Capizzi M, Strappazzon F, Cianfanelli V, Papaleo E, Cecconi F. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. Autophagy. 0. PMID 28059583 DOI: 10.1080/15548627.2016.1269989  0.349
2017 Schoenherr C, Byron A, Sandilands E, Paliashvili K, Baillie GS, Garcia-Munoz A, Valacca C, Cecconi F, Serrels B, Frame MC. Author response: Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks Elife. DOI: 10.7554/Elife.23172.029  0.308
2016 Ceci R, Duranti G, Leonetti A, Pietropaoli S, Spinozzi F, Marcocci L, Amendola R, Cecconi F, Sabatini S, Mariottini P, Cervelli M. Adaptive responses of heart and skeletal muscle to spermine oxidase overexpression: Evaluation of a new transgenic mouse model. Free Radical Biology & Medicine. 103: 216-225. PMID 28043891 DOI: 10.1016/j.freeradbiomed.2016.12.040  0.306
2016 Nazio F, Carinci M, Valacca C, Bielli P, Strappazzon F, Antonioli M, Ciccosanti F, Rodolfo C, Campello S, Fimia GM, Sette C, Bonaldo P, Cecconi F. Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation. The Journal of Cell Biology. PMID 27932573 DOI: 10.1083/jcb.201605089  0.414
2016 Fiacco E, Castagnetti F, Bianconi V, Madaro L, De Bardi M, Nazio F, D'Amico A, Bertini E, Cecconi F, Puri PL, Latella L. Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles. Cell Death and Differentiation. PMID 27447110 DOI: 10.1038/cdd.2016.70  0.374
2016 Corrado M, Mariotti FR, Trapani L, Taraborrelli L, Nazio F, Cianfanelli V, Soriano ME, Schrepfer E, Cecconi F, Scorrano L, Campello S. Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis. The Embo Journal. PMID 27390127 DOI: 10.15252/embj.201593727  0.466
2016 Campello S, Cecconi F. Fanconi Anemia Genes, of Menders and Sweepers. Developmental Cell. 37: 299-300. PMID 27219059 DOI: 10.1016/j.devcel.2016.05.011  0.31
2016 Rizza S, Montagna C, Cardaci S, Maiani E, Di Giacomo G, Sanchez-Quiles V, Blagoev B, Rasola A, De Zio D, Stamler JS, Cecconi F, Filomeni G. S-nitrosylation of the mitochondrial chaperone TRAP1 sensitizes hepatocellular carcinoma cells to inhibitors of succinate dehydrogenase. Cancer Research. PMID 27216192 DOI: 10.1158/0008-5472.Can-15-2637  0.707
2016 Strappazzon F, Di Rita A, Cianfanelli V, D'Orazio M, Nazio F, Fimia GM, Cecconi F. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 1-13. PMID 27123694 DOI: 10.1080/15548627.2016.1164359  0.453
2016 Montagna C, Rizza S, Maiani E, Piredda L, Filomeni G, Cecconi F. To eat, or NOt to eat: S-nitrosylation signaling in autophagy. The Febs Journal. PMID 27083138 DOI: 10.1111/febs.13736  0.427
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Cecconi F, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.693
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Cecconi F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.797
2015 Strappazzon F, Cecconi F. AMBRA1-induced mitophagy: A new mechanism to cope with cancer? Molecular & Cellular Oncology. 2: e975647. PMID 27308437 DOI: 10.4161/23723556.2014.975647  0.386
2015 Cianfanelli V, Nazio F, Cecconi F. Connecting autophagy: AMBRA1 and its network of regulation. Molecular & Cellular Oncology. 2: e970059. PMID 27308402 DOI: 10.4161/23723548.2014.970059  0.465
2015 Martinez-Lopez N, Garcia-Macia M, Sahu S, Athonvarangkul D, Liebling E, Merlo P, Cecconi F, Schwartz GJ, Singh R. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metabolism. PMID 26698918 DOI: 10.1016/j.cmet.2015.10.008  0.355
2015 Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, Grumati P, Bonaldo P. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 0. PMID 26565691 DOI: 10.1080/15548627.2015.1108508  0.352
2015 Cervetto C, Vergani L, Passalacqua M, Ragazzoni M, Venturini A, Cecconi F, Berretta N, Mercuri N, D'Amelio M, Maura G, Mariottini P, Voci A, Marcoli M, Cervelli M. Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse. Neuromolecular Medicine. PMID 26530396 DOI: 10.1007/S12017-015-8377-3  0.564
2015 Cecconi F, Soucek L, Taub DD, Ziparo E. Live or Die: Choice Mechanisms in Stressed Cells. Mediators of Inflammation. 2015: 454863. PMID 26508817 DOI: 10.1155/2015/454863  0.439
2015 Rodolfo C, Di Bartolomeo S, Cecconi F. Autophagy in stem and progenitor cells. Cellular and Molecular Life Sciences : Cmls. PMID 26502349 DOI: 10.1007/s00018-015-2071-3  0.653
2015 Rizza S, Cirotti C, Montagna C, Cardaci S, Consales C, Cozzolino M, Carrì MT, Cecconi F, Filomeni G. S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis. Mediators of Inflammation. 2015: 536238. PMID 26491229 DOI: 10.1155/2015/536238  0.32
2015 Schiavi A, Maglioni S, Palikaras K, Shaik A, Strappazzon F, Brinkmann V, Torgovnick A, Castelein N, De Henau S, Braeckman BP, Cecconi F, Tavernarakis N, Ventura N. Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans. Current Biology : Cb. 25: 1810-22. PMID 26144971 DOI: 10.1016/J.Cub.2015.05.059  0.36
2015 Cianfanelli V, Cecconi F. AMBRA1: When autophagy meets cell proliferation. Autophagy. 11: 1705-7. PMID 26101901 DOI: 10.1080/15548627.2015.1053681  0.467
2015 Pourpirali S, Valacca C, Merlo P, Rizza S, D'Amico S, Cecconi F. Prolonged Pseudohypoxia Targets Ambra1 mRNA to P-Bodies for Translational Repression. Plos One. 10: e0129750. PMID 26086269 DOI: 10.1371/journal.pone.0129750  0.408
2015 Cianfanelli V, De Zio D, Di Bartolomeo S, Nazio F, Strappazzon F, Cecconi F. Ambra1 at a glance. Journal of Cell Science. 128: 2003-8. PMID 26034061 DOI: 10.1242/jcs.168153  0.815
2015 Catalano M, D'Alessandro G, Lepore F, Corazzari M, Caldarola S, Valacca C, Faienza F, Esposito V, Limatola C, Cecconi F, Di Bartolomeo S. Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells. Molecular Oncology. PMID 26022108 DOI: 10.1016/j.molonc.2015.04.016  0.656
2015 Porcellotti S, Fanelli F, Fracassi A, Sepe S, Cecconi F, Bernardi C, Cimini A, Cerù MP, Moreno S. Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2015: 967203. PMID 25973140 DOI: 10.1155/2015/967203  0.303
2015 Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, ... ... Cecconi F, et al. Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nature Cell Biology. 17: 706. PMID 25925585 DOI: 10.1038/Ncb3171  0.791
2015 Strappazzon F, Cecconi F. The multifaceted mitochondrion: An attractive candidate for therapeutic strategies. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. PMID 25818167 DOI: 10.1016/j.phrs.2015.03.007  0.346
2015 Cianfanelli V, D'Orazio M, Cecconi F. AMBRA1 and BECLIN 1 interplay in the crosstalk between autophagy and cell proliferation. Cell Cycle (Georgetown, Tex.). 14: 959-63. PMID 25803737 DOI: 10.1080/15384101.2015.1021526  0.451
2015 Galluzzi L, Pietrocola F, Bravo-San Pedro JM, Amaravadi RK, Baehrecke EH, Cecconi F, Codogno P, Debnath J, Gewirtz DA, Karantza V, Kimmelman A, Kumar S, Levine B, Maiuri MC, Martin SJ, et al. Autophagy in malignant transformation and cancer progression. The Embo Journal. 34: 856-80. PMID 25712477 DOI: 10.15252/Embj.201490784  0.579
2015 Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell Death and Differentiation. 22: 517. PMID 25661525 DOI: 10.1038/cdd.2014.190  0.462
2015 Niso-Santano M, Malik SA, Pietrocola F, Bravo-San Pedro JM, Mariño G, Cianfanelli V, Ben-Younès A, Troncoso R, Markaki M, Sica V, Izzo V, Chaba K, Bauvy C, Dupont N, Kepp O, ... ... Cecconi F, et al. Unsaturated fatty acids induce non-canonical autophagy. The Embo Journal. 34: 1025-41. PMID 25586377 DOI: 10.15252/Embj.201489363  0.385
2015 Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, ... ... Cecconi F, et al. AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nature Cell Biology. 17: 20-30. PMID 25438055 DOI: 10.1038/Ncb3072  0.813
2015 Filomeni G, De Zio D, Cecconi F. Oxidative stress and autophagy: the clash between damage and metabolic needs. Cell Death and Differentiation. 22: 377-88. PMID 25257172 DOI: 10.1038/cdd.2014.150  0.722
2015 Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Cecconi F, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137  0.595
2015 Strappazzon F, Nazio F, Corrado M, Cianfanelli V, Romagnoli A, Fimia GM, Campello S, Nardacci R, Piacentini M, Campanella M, Cecconi F. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell Death and Differentiation. 22: 419-32. PMID 25215947 DOI: 10.1038/cdd.2014.139  0.575
2015 Cianfanelli V, De Zio D, Di Bartolomeo S, Nazio F, Strappazzon F, Cecconi F. Ambra1 at a glance Journal of Cell Science. 128: 2003-2008. DOI: 10.1242/jcs.168153  0.747
2014 Cecconi F, Jäättelä M. Targeting ions-induced autophagy in cancer. Cancer Cell. 26: 599-600. PMID 25517744 DOI: 10.1016/j.ccell.2014.10.014  0.387
2014 Antonioli M, Albiero F, Nazio F, Vescovo T, Perdomo AB, Corazzari M, Marsella C, Piselli P, Gretzmeier C, Dengjel J, Cecconi F, Piacentini M, Fimia GM. AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics. Developmental Cell. 31: 734-46. PMID 25499913 DOI: 10.1016/j.devcel.2014.11.013  0.577
2014 Yazdankhah M, Farioli-Vecchioli S, Tonchev AB, Stoykova A, Cecconi F. The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone. Cell Death & Disease. 5: e1403. PMID 25188513 DOI: 10.1038/cddis.2014.358  0.453
2014 Skobo T, Benato F, Grumati P, Meneghetti G, Cianfanelli V, Castagnaro S, Chrisam M, Di Bartolomeo S, Bonaldo P, Cecconi F, Dalla Valle L. Zebrafish ambra1a and ambra1b knockdown impairs skeletal muscle development. Plos One. 9: e99210. PMID 24922546 DOI: 10.1371/journal.pone.0099210  0.595
2014 Montagna C, Di Giacomo G, Rizza S, Cardaci S, Ferraro E, Grumati P, De Zio D, Maiani E, Muscoli C, Lauro F, Ilari S, Bernardini S, Cannata S, Gargioli C, Ciriolo MR, ... Cecconi F, et al. S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction. Antioxidants & Redox Signaling. 21: 570-87. PMID 24684653 DOI: 10.1089/ars.2013.5696  0.738
2014 Benedetti E, D'Angelo B, Cristiano L, Di Giacomo E, Fanelli F, Moreno S, Cecconi F, Fidoamore A, Antonosante A, Falcone R, Ippoliti R, Giordano A, Cimini A. Involvement of peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in BDNF signaling during aging and in Alzheimer disease: possible role of 4-hydroxynonenal (4-HNE). Cell Cycle (Georgetown, Tex.). 13: 1335-44. PMID 24621497 DOI: 10.4161/Cc.28295  0.305
2014 Campello S, Cecconi F. Ho(a)xing autophagy to regulate development. Developmental Cell. 28: 3-4. PMID 24434134 DOI: 10.1016/j.devcel.2013.12.018  0.394
2014 Sancho M, Gortat A, Herrera AE, Andreu-Fernández V, Ferraro E, Cecconi F, Orzáez M, Pérez-Payá E. Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells. Plos One. 9: e84666. PMID 24416260 DOI: 10.1371/journal.pone.0084666  0.664
2014 Campello S, Strappazzon F, Cecconi F. Mitochondrial dismissal in mammals, from protein degradation to mitophagy. Biochimica Et Biophysica Acta. 1837: 451-60. PMID 24275087 DOI: 10.1016/j.bbabio.2013.11.010  0.379
2014 Marinelli S, Nazio F, Tinari A, Ciarlo L, D'Amelio M, Pieroni L, Vacca V, Urbani A, Cecconi F, Malorni W, Pavone F. Schwann cell autophagy counteracts the onset and chronification of neuropathic pain. Pain. 155: 93-107. PMID 24041962 DOI: 10.1016/j.pain.2013.09.013  0.603
2014 Sepe S, Nardacci R, Fanelli F, Rosso P, Bernardi C, Cecconi F, Mastroberardino PG, Piacentini M, Moreno S. Expression of Ambra1 in mouse brain during physiological and Alzheimer type aging. Neurobiology of Aging. 35: 96-108. PMID 23910655 DOI: 10.1016/J.Neurobiolaging.2013.07.001  0.56
2013 Cianfanelli V, Cecconi F. Cell biology: Molecular clearance at the cell's antenna. Nature. 502: 180-1. PMID 24089206 DOI: 10.1038/nature12693  0.413
2013 Nazio F, Cecconi F. mTOR, AMBRA1, and autophagy: an intricate relationship. Cell Cycle (Georgetown, Tex.). 12: 2524-5. PMID 23907135 DOI: 10.4161/cc.25835  0.447
2013 Cervelli M, Bellavia G, D'Amelio M, Cavallucci V, Moreno S, Berger J, Nardacci R, Marcoli M, Maura G, Piacentini M, Amendola R, Cecconi F, Mariottini P. A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to Excitotoxic Injury. Plos One. 8: e64810. PMID 23840306 DOI: 10.1371/journal.pone.0064810  0.67
2013 Merlo P, Cecconi F. XIAP: inhibitor of two worlds. The Embo Journal. 32: 2187-8. PMID 23792426 DOI: 10.1038/emboj.2013.152  0.406
2013 Nazio F, Strappazzon F, Antonioli M, Bielli P, Cianfanelli V, Bordi M, Gretzmeier C, Dengjel J, Piacentini M, Fimia GM, Cecconi F. mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nature Cell Biology. 15: 406-16. PMID 23524951 DOI: 10.1038/ncb2708  0.563
2013 Fanelli F, Sepe S, D'Amelio M, Bernardi C, Cristiano L, Cimini A, Cecconi F, Ceru' MP, Moreno S. Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease. Molecular Neurodegeneration. 8: 8. PMID 23374228 DOI: 10.1186/1750-1326-8-8  0.586
2013 De Zio D, Cianfanelli V, Cecconi F. New insights into the link between DNA damage and apoptosis. Antioxidants & Redox Signaling. 19: 559-71. PMID 23025416 DOI: 10.1089/ars.2012.4938  0.703
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Cecconi F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.684
2012 Tatti M, Motta M, Di Bartolomeo S, Scarpa S, Cianfanelli V, Cecconi F, Salvioli R. Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts. Human Molecular Genetics. 21: 5159-73. PMID 22949512 DOI: 10.1093/hmg/dds367  0.603
2012 D'Amelio M, Sheng M, Cecconi F. Caspase-3 in the central nervous system: beyond apoptosis. Trends in Neurosciences. 35: 700-9. PMID 22796265 DOI: 10.1016/j.tins.2012.06.004  0.658
2012 De Zio D, Bordi M, Cecconi F. Oxidative DNA damage in neurons: implication of ku in neuronal homeostasis and survival. International Journal of Cell Biology. 2012: 752420. PMID 22737170 DOI: 10.1155/2012/752420  0.686
2012 Pagliarini V, Wirawan E, Romagnoli A, Ciccosanti F, Lisi G, Lippens S, Cecconi F, Fimia GM, Vandenabeele P, Corazzari M, Piacentini M. Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response. Cell Death and Differentiation. 19: 1495-504. PMID 22441670 DOI: 10.1038/cdd.2012.27  0.621
2012 Cavallucci V, D'Amelio M, Cecconi F. Aβ toxicity in Alzheimer's disease. Molecular Neurobiology. 45: 366-78. PMID 22415442 DOI: 10.1007/s12035-012-8251-3  0.567
2012 Strappazzon F, Campello S, Cecconi F. Non-apoptotic roles for death-related molecules: when mitochondria chose cell fate. Experimental Cell Research. 318: 1309-15. PMID 22342457 DOI: 10.1016/j.yexcr.2012.01.027  0.41
2012 D'Eletto M, Farrace MG, Rossin F, Strappazzon F, Giacomo GD, Cecconi F, Melino G, Sepe S, Moreno S, Fimia GM, Falasca L, Nardacci R, Piacentini M. Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins. Cell Death and Differentiation. 19: 1228-38. PMID 22322858 DOI: 10.1038/cdd.2012.2  0.548
2012 Cianfanelli V, Cecconi F. Autophagy-dependent NFκB regulation. Cell Cycle (Georgetown, Tex.). 11: 436-7. PMID 22262191 DOI: 10.4161/cc.11.3.19224  0.412
2012 Viscomi MT, D'Amelio M, Cavallucci V, Latini L, Bisicchia E, Nazio F, Fanelli F, Maccarrone M, Moreno S, Cecconi F, Molinari M. Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage. Autophagy. 8: 222-35. PMID 22248716 DOI: 10.4161/auto.8.2.18599  0.622
2012 Vázquez P, Arroba AI, Cecconi F, de la Rosa EJ, Boya P, de Pablo F. Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells. Autophagy. 8: 187-99. PMID 22240590 DOI: 10.4161/auto.8.2.18535  0.359
2012 Cecconi F. c-Cbl targets active Src for autophagy. Nature Cell Biology. 14: 48-9. PMID 22193164 DOI: 10.1038/ncb2413  0.382
2012 Franzke N, Koehler S, Middel P, Fuoco C, Cecconi F, Quondamatteo F, Laskawi R, Rohrbach S. Localization of Active Caspase-3 and Caspase-8 in Nasal Polyps and Nasal Hyperplasia in Consideration of Mast Cell Function: A Semiquantitatively Analysis International Journal of Otolaryngology and Head &Amp; Neck Surgery. 1: 63-70. DOI: 10.4236/IJOHNS.2012.13014  0.404
2011 Cecconi F. Autophagy regulation by miRNAs: when cleaning goes out of service. The Embo Journal. 30: 4517-9. PMID 22085996 DOI: 10.1038/emboj.2011.387  0.41
2011 Ferraro E, Pesaresi MG, De Zio D, Cencioni MT, Gortat A, Cozzolino M, Berghella L, Salvatore AM, Oettinghaus B, Scorrano L, Pérez-Payà E, Cecconi F. Apaf1 plays a pro-survival role by regulating centrosome morphology and function. Journal of Cell Science. 124: 3450-63. PMID 21984814 DOI: 10.1242/jcs.086298  0.808
2011 Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy. The Embo Journal. 30: 1195-208. PMID 21358617 DOI: 10.1038/emboj.2011.49  0.582
2011 D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, Ferri A, Diamantini A, De Zio D, Carrara P, Battistini L, Moreno S, Bacci A, Ammassari-Teule M, Marie H, Cecconi F. Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nature Neuroscience. 14: 69-76. PMID 21151119 DOI: 10.1038/nn.2709  0.761
2011 Fimia GM, Di Bartolomeo S, Piacentini M, Cecconi F. Unleashing the Ambra1-Beclin 1 complex from dynein chains: Ulk1 sets Ambra1 free to induce autophagy. Autophagy. 7: 115-7. PMID 21079415 DOI: 10.4161/auto.7.1.14071  0.693
2011 De Zio D, Bordi M, Tino E, Lanzuolo C, Ferraro E, Mora E, Ciccosanti F, Fimia GM, Orlando V, Cecconi F. The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage. Cell Death and Differentiation. 18: 516-27. PMID 20966962 DOI: 10.1038/cdd.2010.125  0.782
2011 Cecconi F, Bartolomeo SD. CASP-9 (caspase 9, apoptosis-related cysteine peptidase) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/38402  0.392
2011 Corvaro M, Cecconi F. APAF1 (apoptotic protease activating factor 1) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/38124  0.319
2010 Di Bartolomeo S, Corazzari M, Nazio F, Oliverio S, Lisi G, Antonioli M, Pagliarini V, Matteoni S, Fuoco C, Giunta L, D'Amelio M, Nardacci R, Romagnoli A, Piacentini M, Cecconi F, et al. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. The Journal of Cell Biology. 191: 155-68. PMID 20921139 DOI: 10.1083/jcb.201002100  0.766
2010 Di Bartolomeo S, Nazio F, Cecconi F. The role of autophagy during development in higher eukaryotes. Traffic (Copenhagen, Denmark). 11: 1280-9. PMID 20633243 DOI: 10.1111/j.1600-0854.2010.01103.x  0.685
2010 Hangen E, De Zio D, Bordi M, Zhu C, Dessen P, Caffin F, Lachkar S, Perfettini JL, Lazar V, Benard J, Fimia GM, Piacentini M, Harper F, Pierron G, Vicencio JM, ... ... Cecconi F, et al. A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2. Cell Death and Differentiation. 17: 1155-66. PMID 20111043 DOI: 10.1038/Cdd.2009.211  0.762
2010 D'Amelio M, Cavallucci V, Cecconi F. Neuronal caspase-3 signaling: not only cell death. Cell Death and Differentiation. 17: 1104-14. PMID 19960023 DOI: 10.1038/cdd.2009.180  0.651
2010 Ioannides AS, Massa V, Ferraro E, Cecconi F, Spitz L, Henderson DJ, Copp AJ. Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death. Developmental Biology. 337: 351-62. PMID 19913007 DOI: 10.1016/j.ydbio.2009.11.005  0.622
2010 Ferraro E, Fuoco C, Strappazzon F, Cecconi F. Apoptosome structure and regulation Apoptosome: An Up-and-Coming Therapeutical Tool. 27-39. DOI: 10.1007/978-90-481-3415-1-2  0.491
2010 D'Amelio M, Cecconi F. Apoptosome pharmacological manipulation: From current developments in the laboratory to clinical implications Apoptosome: An Up-and-Coming Therapeutical Tool. 271-281. DOI: 10.1007/978-90-481-3415-1-14  0.469
2010 Cecconi F, D'Amelio M. Apoptosome: An up-and-coming therapeutical tool Apoptosome: An Up-and-Coming Therapeutical Tool. 1-322. DOI: 10.1007/978-90-481-3415-1  0.476
2009 Cimini A, Moreno S, D'Amelio M, Cristiano L, D'Angelo B, Falone S, Benedetti E, Carrara P, Fanelli F, Cecconi F, Amicarelli F, Cerù MP. Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: a role for peroxisomes. Journal of Alzheimer's Disease : Jad. 18: 935-52. PMID 19749434 DOI: 10.3233/JAD-2009-1199  0.578
2009 Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, Nowak J, Fimia GM, Piacentini M, Cecconi F, Pandolfi PP, et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. The Journal of Clinical Investigation. 119: 1359-72. PMID 19425170 DOI: 10.1172/Jci37948  0.601
2009 Massa V, Savery D, Ybot-Gonzalez P, Ferraro E, Rongvaux A, Cecconi F, Flavell R, Greene ND, Copp AJ. Apoptosis is not required for mammalian neural tube closure. Proceedings of the National Academy of Sciences of the United States of America. 106: 8233-8. PMID 19420217 DOI: 10.1073/Pnas.0900333106  0.616
2009 D'Amelio M, Cecconi F. A novel player in the p53-mediated autophagy: Sestrin2. Cell Cycle (Georgetown, Tex.). 8: 1467. PMID 19411829 DOI: 10.4161/Cc.8.10.8767  0.583
2009 Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D'Amelio M, Cavallucci V, Martorana A, Bergamaschi A, Cencioni MT, Diamantini A, Butti E, Comi G, ... ... Cecconi F, et al. Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3442-52. PMID 19295150 DOI: 10.1523/Jneurosci.5804-08.2009  0.622
2008 Cecconi F, Levine B. The role of autophagy in mammalian development: cell makeover rather than cell death. Developmental Cell. 15: 344-57. PMID 18804433 DOI: 10.1016/j.devcel.2008.08.012  0.496
2008 Tattoli I, Lembo-Fazio L, Nigro G, Carneiro LA, Ferraro E, Rossi G, Martino MC, de Stefano ME, Cecconi F, Girardin SE, Philpott DJ, Bernardini ML. Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells. Microbes and Infection / Institut Pasteur. 10: 1114-23. PMID 18606244 DOI: 10.1016/J.Micinf.2008.06.004  0.631
2008 Tasdemir E, Chiara Maiuri M, Morselli E, Criollo A, D'Amelio M, Djavaheri-Mergny M, Cecconi F, Tavernarakis N, Kroemer G. A dual role of p53 in the control of autophagy. Autophagy. 4: 810-4. PMID 18604159 DOI: 10.4161/Auto.6486  0.606
2008 D'Amelio M, Cavallucci V, Diamantini A, Cecconi F. Analysis of neuronal cell death in mammals. Methods in Enzymology. 446: 259-76. PMID 18603127 DOI: 10.1016/S0076-6879(08)01615-7  0.662
2008 Ferraro E, Pulicati A, Cencioni MT, Cozzolino M, Navoni F, di Martino S, Nardacci R, Carrì MT, Cecconi F. Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis. Molecular Biology of the Cell. 19: 3576-88. PMID 18550800 DOI: 10.1091/mbc.E07-09-0858  0.661
2008 De Zio D, Ferraro E, D'Amelio M, Simoni V, Bordi M, Soroldoni D, Berghella L, Meyer BI, Cecconi F. Faf1 is expressed during neurodevelopment and is involved in Apaf1-dependent caspase-3 activation in proneural cells. Cellular and Molecular Life Sciences : Cmls. 65: 1780-90. PMID 18480964 DOI: 10.1007/s00018-008-8075-5  0.82
2008 Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, Criollo A, Morselli E, Zhu C, Harper F, Nannmark U, Samara C, Pinton P, Vicencio JM, Carnuccio R, ... ... Cecconi F, et al. Regulation of autophagy by cytoplasmic p53. Nature Cell Biology. 10: 676-87. PMID 18454141 DOI: 10.1038/Ncb1730  0.628
2008 Cecconi F, Piacentini M, Fimia GM. The involvement of cell death and survival in neural tube defects: a distinct role for apoptosis and autophagy? Cell Death and Differentiation. 15: 1170-7. PMID 18451869 DOI: 10.1038/cdd.2008.64  0.607
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Cecconi F, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/Auto.5338  0.517
2008 D'Amelio M, Tino E, Cecconi F. The apoptosome: emerging insights and new potential targets for drug design. Pharmaceutical Research. 25: 740-51. PMID 17674158 DOI: 10.1007/s11095-007-9396-z  0.629
2007 Zermati Y, Mouhamad S, Stergiou L, Besse B, Galluzzi L, Boehrer S, Pauleau AL, Rosselli F, D'Amelio M, Amendola R, Castedo M, Hengartner M, Soria JC, Cecconi F, Kroemer G. Nonapoptotic role for Apaf-1 in the DNA damage checkpoint. Molecular Cell. 28: 624-37. PMID 18042457 DOI: 10.1016/J.Molcel.2012.10.006  0.628
2007 Cecconi F, Di Bartolomeo S, Nardacci R, Fuoco C, Corazzari M, Giunta L, Romagnoli A, Stoykova A, Chowdhury K, Fimia GM, Piacentini M. A novel role for autophagy in neurodevelopment. Autophagy. 3: 506-8. PMID 17622796 DOI: 10.4161/Auto.4616  0.754
2007 Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, Corazzari M, Fuoco C, Ucar A, Schwartz P, Gruss P, Piacentini M, Chowdhury K, Cecconi F. Ambra1 regulates autophagy and development of the nervous system. Nature. 447: 1121-5. PMID 17589504 DOI: 10.1038/nature05925  0.797
2007 Ferraro E, Cecconi F. Autophagic and apoptotic response to stress signals in mammalian cells. Archives of Biochemistry and Biophysics. 462: 210-9. PMID 17374522 DOI: 10.1016/j.abb.2007.02.006  0.668
2007 Berger J, Berger S, Tuoc TC, D'Amelio M, Cecconi F, Gorski JA, Jones KR, Gruss P, Stoykova A. Conditional activation of Pax6 in the developing cortex of transgenic mice causes progenitor apoptosis. Development (Cambridge, England). 134: 1311-22. PMID 17329367 DOI: 10.1242/Dev.02809  0.68
2007 Corvaro M, Fuoco C, Wagner M, Cecconi F. Analysis of apoptosome dysregulation in pancreatic cancer and of its role in chemoresistance. Cancer Biology & Therapy. 6: 209-17. PMID 17224646 DOI: 10.4161/Cbt.6.2.3622  0.432
2006 Moreno S, Imbroglini V, Ferraro E, Bernardi C, Romagnoli A, Berrebi AS, Cecconi F. Apoptosome impairment during development results in activation of an autophagy program in cerebral cortex. Apoptosis : An International Journal On Programmed Cell Death. 11: 1595-602. PMID 16820961 DOI: 10.1007/s10495-006-9081-4  0.673
2006 Di Sano F, Ferraro E, Tufi R, Achsel T, Piacentini M, Cecconi F. Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. The Journal of Biological Chemistry. 281: 2693-700. PMID 16317003 DOI: 10.1074/jbc.M509110200  0.716
2006 Cozzolino M, Ferri A, Ferraro E, Rotilio G, Cecconi F, Carrì MT. Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis. Neurobiology of Disease. 21: 69-79. PMID 16046141 DOI: 10.1016/j.nbd.2005.06.010  0.647
2005 Müller M, Berger J, Gersdorff N, Cecconi F, Herken R, Quondamatteo F. Localization of Apaf1 gene expression in the early development of the mouse by means of in situ reverse transcriptase-polymerase chain reaction. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 215-21. PMID 16086359 DOI: 10.1002/dvdy.20534  0.417
2005 De Zio D, Giunta L, Corvaro M, Ferraro E, Cecconi F. Expanding roles of programmed cell death in mammalian neurodevelopment. Seminars in Cell & Developmental Biology. 16: 281-94. PMID 15797838 DOI: 10.1016/j.semcdb.2004.12.003  0.795
2004 Cozzolino M, Ferraro E, Ferri A, Rigamonti D, Quondamatteo F, Ding H, Xu ZS, Ferrari F, Angelini DF, Rotilio G, Cattaneo E, Carrì MT, Cecconi F. Apoptosome inactivation rescues proneural and neural cells from neurodegeneration. Cell Death and Differentiation. 11: 1179-91. PMID 15257302 DOI: 10.1038/Sj.Cdd.4401476  0.656
2004 Cecconi F, Roth KA, Dolgov O, Munarriz E, Anokhin K, Gruss P, Salminen M. Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth. Development (Cambridge, England). 131: 2125-35. PMID 15105372 DOI: 10.1242/Dev.01082  0.618
2003 D'Sa C, Klocke BJ, Cecconi F, Lindsten T, Thompson CB, Korsmeyer SJ, Flavell RA, Roth KA. Caspase regulation of genotoxin-induced neural precursor cell death. Journal of Neuroscience Research. 74: 435-45. PMID 14598320 DOI: 10.1002/Jnr.10738  0.44
2003 Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ. Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization. The Embo Journal. 22: 4385-99. PMID 12941691 DOI: 10.1093/Emboj/Cdg423  0.446
2003 Ferraro E, Corvaro M, Cecconi F. Physiological and pathological roles of Apaf1 and the apoptosome. Journal of Cellular and Molecular Medicine. 7: 21-34. PMID 12767258 DOI: 10.1111/J.1582-4934.2003.Tb00199.X  0.662
2002 Candé C, Cecconi F, Dessen P, Kroemer G. Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? Journal of Cell Science. 115: 4727-34. PMID 12432061 DOI: 10.1242/Jcs.00210  0.451
2002 Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM, et al. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 419: 634-7. PMID 12374983 DOI: 10.1038/Nature01101  0.434
2002 Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, Yu SW, Dawson TM, Dawson VL, Park DS, Kroemer G, Slack RS. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. The Journal of Cell Biology. 158: 507-17. PMID 12147675 DOI: 10.1083/Jcb.200202130  0.423
2002 Matsuki Y, Zhang HG, Hsu HC, Yang PA, Zhou T, Dodd CH, Cecconi F, Gruss P, Tadakuma T, Mountz JD. Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture. Scandinavian Journal of Immunology. 56: 174-84. PMID 12121437 DOI: 10.1046/J.1365-3083.2002.01120.X  0.519
2002 O'Reilly LA, Ekert P, Harvey N, Marsden V, Cullen L, Vaux DL, Hacker G, Magnusson C, Pakusch M, Cecconi F, Kuida K, Strasser A, Huang DC, Kumar S. Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death and Differentiation. 9: 832-41. PMID 12107826 DOI: 10.1038/Sj.Cdd.4401033  0.421
2002 Bitzer M, Armeanu S, Prinz F, Ungerechts G, Wybranietz W, Spiegel M, Bernlöhr C, Cecconi F, Gregor M, Neubert WJ, Schulze-Osthoff K, Lauer UM. Caspase-8 and Apaf-1-independent caspase-9 activation in Sendai virus-infected cells. The Journal of Biological Chemistry. 277: 29817-24. PMID 12021264 DOI: 10.1074/jbc.M111898200  0.419
2002 Heins N, Malatesta P, Cecconi F, Nakafuku M, Tucker KL, Hack MA, Chapouton P, Barde YA, Götz M. Glial cells generate neurons: the role of the transcription factor Pax6. Nature Neuroscience. 5: 308-15. PMID 11896398 DOI: 10.1038/Nn828  0.329
2002 Moreno S, Ferraro E, Eckert S, Cecconi F. Apaf1 reduced expression levels generate a mutant phenotype in adult brain and skeleton. Cell Death and Differentiation. 9: 340-2. PMID 11859416 DOI: 10.1038/sj.cdd.4400994  0.521
2002 Cecconi F, Gruss P. From ES cells to mice: the gene trap approach. Methods in Molecular Biology (Clifton, N.J.). 185: 335-46. PMID 11768999 DOI: 10.1385/1-59259-241-4:335  0.487
2001 Cecconi F, Gruss P. Apaf1 in developmental apoptosis and cancer: how many ways to die? Cellular and Molecular Life Sciences : Cmls. 58: 1688-97. PMID 11706994 DOI: 10.1007/PL00000806  0.61
2001 Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS, Hakim A, Albert PR, Cecconi F, Helin K, Park DS, Slack RS. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. The Journal of Cell Biology. 155: 207-16. PMID 11591730 DOI: 10.1083/Jcb.200105137  0.372
2001 Moroni MC, Hickman ES, Lazzerini Denchi E, Caprara G, Colli E, Cecconi F, Müller H, Helin K. Apaf-1 is a transcriptional target for E2F and p53. Nature Cell Biology. 3: 552-8. PMID 11389439 DOI: 10.1038/35078527  0.45
2000 Schwarz M, Cecconi F, Bernier G, Andrejewski N, Kammandel B, Wagner M, Gruss P. Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development (Cambridge, England). 127: 4325-34. PMID 11003833  0.423
2000 Alvarez-Bolado G, Zhou X, Cecconi F, Gruss P. Expression of Foxb1 reveals two strategies for the formation of nuclei in the developing ventral diencephalon. Developmental Neuroscience. 22: 197-206. PMID 10894983 DOI: 10.1159/000017442  0.528
1999 Cecconi F. Apaf1 and the apoptotic machinery. Cell Death and Differentiation. 6: 1087-98. PMID 10578178 DOI: 10.1038/sj.cdd.4400602  0.438
1999 Chautan M, Chazal G, Cecconi F, Gruss P, Golstein P. Interdigital cell death can occur through a necrotic and caspase-independent pathway. Current Biology : Cb. 9: 967-70. PMID 10508592 DOI: 10.1016/S0960-9822(99)80425-4  0.622
1999 Alvarez-Bolado G, Cecconi F, Wehr R, Gruss P. The fork head transcription factor Fkh5/Mf3 is a developmental marker gene for superior colliculus layers and derivatives of the hindbrain somatic afferent zone. Brain Research. Developmental Brain Research. 112: 205-15. PMID 9878737 DOI: 10.1016/S0165-3806(98)00176-X  0.493
1998 Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell. 94: 727-37. PMID 9753320 DOI: 10.1016/S0092-8674(00)81732-8  0.61
1997 Cecconi F, Proetzel G, Alvarez-Bolado G, Jay D, Gruss P. Expression of Meis2, a Knotted-related murine homeobox gene, indicates a role in the differentiation of the forebrain and the somitic mesoderm. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 210: 184-90. PMID 9337138 DOI: 10.1002/(Sici)1097-0177(199710)210:2<184::Aid-Aja10>3.0.Co;2-E  0.506
1996 Crosio C, Cecconi F, Mariottini P, Cesareni G, Brenner S, Amaldi F. Fugu intron oversize reveals the presence of U15 snoRNA coding sequences in some introns of the ribosomal protein S3 gene. Genome Research. 6: 1227-31. PMID 8973918 DOI: 10.1101/Gr.6.12.1227  0.599
1996 Cecconi F, Crosio C, Mariottini P, Cesareni G, Giorgi M, Brenner S, Amaldi F. A functional role for some Fugu introns larger than the typical short ones: the example of the gene coding for ribosomal protein S7 and snoRNA U17. Nucleic Acids Research. 24: 3167-72. PMID 8774896 DOI: 10.1093/Nar/24.16.3167  0.603
1995 Amaldi F, Camacho-Vanegas O, Cardinall B, Cecconi F, Crosio C, Loreni F, Mariottini P, Pellizzoni L, Pierandrei-Amaldi P. Structure and expression of ribosomal protein genes in Xenopus laevis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 969-77. PMID 8722012 DOI: 10.1139/O95-104  0.632
1995 Cecconi F, Mariottini P, Amaldi F. The Xenopus intron-encoded U17 snoRNA is produced by exonucleolytic processing of its precursor in oocytes. Nucleic Acids Research. 23: 4670-6. PMID 8524659 DOI: 10.1093/Nar/23.22.4670  0.615
1994 Cecconi F, Mariottini P, Loreni F, Pierandrei-Amaldi P, Campioni N, Amaldi F. U17XS8, a small nucleolar RNA with a 12 nt complementarity to 18S rRNA and coded by a sequence repeated in the six introns of Xenopus laevis ribosomal protein S8 gene. Nucleic Acids Research. 22: 732-41. PMID 8139912 DOI: 10.1093/Nar/22.5.732  0.598
1993 Mariottini P, Bagni C, Francesconi A, Cecconi F, Serra MJ, Chen QM, Loreni F, Annesi F, Amaldi F. Sequence of the gene coding for ribosomal protein S8 of Xenopus laevis. Gene. 132: 255-60. PMID 8224872 DOI: 10.1016/0378-1119(93)90204-G  0.699
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