| Year |
Citation |
Score |
| 2023 |
Jin C, Shi Y, Shi L, Leak RK, Zhang W, Chen K, Ye Q, Hassan S, Lyu J, Hu X, Stetler RA, Bennett MVL, Chen J. Leveraging single-cell RNA sequencing to unravel the impact of aging on stroke recovery mechanisms in mice. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300012120. PMID 37307473 DOI: 10.1073/pnas.2300012120 |
0.319 |
|
| 2022 |
Wang M, Thomson AW, Yu F, Hazra R, Junagade A, Hu X. Regulatory T lymphocytes as a therapy for ischemic stroke. Seminars in Immunopathology. PMID 36469056 DOI: 10.1007/s00281-022-00975-z |
0.304 |
|
| 2022 |
Dufort C, Wang Y, Hu X. Microglia: Active participants in brain capillary function. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221119292. PMID 35942567 DOI: 10.1177/0271678X221119292 |
0.675 |
|
| 2022 |
Cai W, Shi L, Zhao J, Xu F, Dufort C, Ye Q, Yang T, Dai X, Lyu J, Jin C, Pu H, Yu F, Hassan S, Sun Z, Zhang W, ... ... Hu X, et al. Neuroprotection against ischemic stroke requires a specific class of early responder T cells in mice. The Journal of Clinical Investigation. 132. PMID 35912857 DOI: 10.1172/JCI157678 |
0.686 |
|
| 2021 |
Shi L, Sun Z, Su W, Xu F, Xie D, Zhang Q, Dai X, Iyer K, Hitchens TK, Foley LM, Li S, Stolz DB, Chen K, Ding Y, Thomson AW, ... ... Hu X, et al. Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. Immunity. PMID 34015256 DOI: 10.1016/j.immuni.2021.04.022 |
0.319 |
|
| 2021 |
Lyu J, Xie D, Bhatia TN, Leak RK, Hu X, Jiang X. Microglial/Macrophage polarization and function in brain injury and repair after stroke. Cns Neuroscience & Therapeutics. PMID 33650313 DOI: 10.1111/cns.13620 |
0.341 |
|
| 2020 |
Shi Y, Zhang L, Pu H, Mao L, Hu X, Jiang X, Xu N, Stetler RA, Zhang F, Liu X, Leak RK, Keep RF, Ji X, Chen J. Publisher Correction: Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury. Nature Communications. 11: 4335. PMID 32843701 DOI: 10.1038/S41467-020-18263-5 |
0.355 |
|
| 2020 |
Pu H, Zheng X, Jiang X, Mu H, Xu F, Zhu W, Ye Q, Jizhang Y, Hitchens TK, Shi Y, Hu X, Leak RK, Dixon CE, Bennett MV, Chen J. Interleukin-4 improves white matter integrity and functional recovery after murine traumatic brain injury via oligodendroglial PPARγ. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20941393. PMID 32757740 DOI: 10.1177/0271678X20941393 |
0.404 |
|
| 2020 |
Shi L, Rocha M, Zhang W, Jiang M, Li S, Ye Q, Hassan SH, Liu L, Adair MN, Xu J, Luo J, Hu X, Wechsler LR, Chen J, Shi Y. Genome-wide transcriptomic analysis of microglia reveals impaired responses in aged mice after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20925655. PMID 32438860 DOI: 10.1177/0271678X20925655 |
0.394 |
|
| 2020 |
Wang R, Pu H, Ye Q, Jiang M, Chen J, Zhao J, Li S, Liu Y, Hu X, Rocha M, Jadhav AP, Chen J, Shi Y. Transforming Growth Factor Beta-Activated Kinase 1-Dependent Microglial and Macrophage Responses Aggravate Long-Term Outcomes After Ischemic Stroke. Stroke. STROKEAHA119028398. PMID 32078472 DOI: 10.1161/Strokeaha.119.028398 |
0.465 |
|
| 2020 |
Jiang L, Mu H, Xu F, Xie D, Su W, Xu J, Sun Z, Liu S, Luo J, Shi Y, Leak RK, Wechsler LR, Chen J, Hu X. Transcriptomic and functional studies reveal undermined chemotactic and angiostimulatory properties of aged microglia during stroke recovery. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20902542. PMID 32065074 DOI: 10.1177/0271678X20902542 |
0.344 |
|
| 2019 |
Wang R, Liu Y, Ye Q, Hassan SH, Zhao J, Li S, Hu X, Leak RK, Rocha M, Wechsler LR, Chen J, Shi Y. RNA sequencing reveals novel macrophage transcriptome favoring neurovascular plasticity after ischemic stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19888630. PMID 31722596 DOI: 10.1177/0271678X19888630 |
0.418 |
|
| 2019 |
Cai W, Dai X, Chen J, Zhao J, Xu M, Zhang L, Yang B, Zhang W, Rocha M, Nakao T, Kofler J, Shi Y, Stetler RA, Hu X, Chen J. STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice. Jci Insight. 4. PMID 31619589 DOI: 10.1172/Jci.Insight.131355 |
0.442 |
|
| 2019 |
Zhang Q, Zhu W, Xu F, Dai X, Shi L, Cai W, Mu H, Hitchens TK, Foley LM, Liu X, Yu F, Chen J, Shi Y, Leak RK, Gao Y, ... ... Hu X, et al. The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury. Plos Biology. 17: e3000330. PMID 31226122 DOI: 10.1371/Journal.Pbio.3000330 |
0.427 |
|
| 2019 |
Pu H, Shi Y, Zhang L, Lu Z, Ye Q, Leak RK, Xu F, Ma S, Mu H, Wei Z, Xu N, Xia Y, Hu X, Hitchens TK, Bennett MVL, et al. Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America. PMID 30996120 DOI: 10.1073/Pnas.1821979116 |
0.427 |
|
| 2019 |
Cai W, Liu S, Hu M, Huang F, Zhu Q, Qiu W, Hu X, Colello J, Zheng SG, Lu Z. Functional Dynamics of Neutrophils After Ischemic Stroke. Translational Stroke Research. PMID 30847778 DOI: 10.1007/S12975-019-00694-Y |
0.399 |
|
| 2019 |
Dai X, Chen J, Xu F, Zhao J, Cai W, Sun Z, Hitchens TK, Foley LM, Leak RK, Chen J, Hu X. TGFα preserves oligodendrocyte lineage cells and improves white matter integrity after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X19830791. PMID 30834805 DOI: 10.1177/0271678X19830791 |
0.436 |
|
| 2019 |
Zhang Q, Zhu W, Yu F, Gao Y, Chen J, Hu X. Abstract 55: Interleukin 4 Improves White Matter Repair After Stroke By Promoting Oligodendrocyte Differentiation Stroke. 50. DOI: 10.1161/Str.50.Suppl_1.55 |
0.399 |
|
| 2018 |
Zhou YX, Wang X, Tang D, Li Y, Jiao YF, Gan Y, Hu XM, Yang LQ, Yu WF, Stetler RA, Li PY, Wen DX. IL-2mAb reduces demyelination after focal cerebral ischemia by suppressing CD8 T cells. Cns Neuroscience & Therapeutics. PMID 30444079 DOI: 10.1111/Cns.13084 |
0.375 |
|
| 2018 |
Wang L, Zhou Y, Yin J, Gan Y, Wang X, Wen D, Thomson AW, Hu X, Yang L, Stetler RA, Li P, Yu W. Cancer Exacerbates Ischemic Brain Injury Via Nrp1 (Neuropilin 1)-Mediated Accumulation of Regulatory T Cells Within the Tumor. Stroke. 49: 2733-2742. PMID 30355201 DOI: 10.1161/Strokeaha.118.021948 |
0.409 |
|
| 2018 |
Ma S, Wang J, Wang Y, Dai X, Xu F, Gao X, Johnson J, Xu N, Leak RK, Hu X, Luo Y, Chen J. Diabetes Mellitus Impairs White Matter Repair and Long-Term Functional Deficits After Cerebral Ischemia. Stroke. 49: 2453-2463. PMID 30355111 DOI: 10.1161/Strokeaha.118.021452 |
0.395 |
|
| 2018 |
Zhang H, Xia Y, Ye Q, Yu F, Zhu W, Li P, Wei Z, Yang Y, Shi Y, Thomson AW, Chen J, Hu X. Expansion of Regulatory T cells with IL-2/IL-2 Antibody Complex Protects against Transient Ischemic Stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30291203 DOI: 10.1523/Jneurosci.3411-17.2018 |
0.341 |
|
| 2018 |
Jiang X, Suenaga J, Pu H, Wei Z, Smith AD, Hu X, Shi Y, Chen J. Post-stroke administration of omega-3 polyunsaturated fatty acids promotes neurovascular restoration after ischemic stroke in mice: Efficacy declines with aging. Neurobiology of Disease. PMID 30218758 DOI: 10.1016/J.Nbd.2018.09.012 |
0.387 |
|
| 2018 |
Cai W, Liu S, Hu M, Sun X, Qiu W, Zheng S, Hu X, Lu Z. Post-stroke DHA Treatment Protects Against Acute Ischemic Brain Injury by Skewing Macrophage Polarity Toward the M2 Phenotype. Translational Stroke Research. PMID 30203370 DOI: 10.1007/S12975-018-0662-7 |
0.43 |
|
| 2018 |
Xia Y, Pu H, Leak RK, Shi Y, Mu H, Hu X, Lu Z, Foley LM, Hitchens TK, Dixon CE, Bennett MVL, Chen J. Tissue plasminogen activator promotes white matter integrity and functional recovery in a murine model of traumatic brain injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201709 DOI: 10.1073/Pnas.1810693115 |
0.415 |
|
| 2018 |
Hu X, Leak RK, Thomson AW, Yu F, Xia Y, Wechsler LR, Chen J. Promises and limitations of immune cell-based therapies in neurological disorders. Nature Reviews. Neurology. PMID 29925925 DOI: 10.1038/S41582-018-0028-5 |
0.351 |
|
| 2018 |
Ran Y, Liu Z, Huang S, Shen J, Li F, Zhang W, Chen C, Geng X, Ji Z, Du H, Hu X. Splenectomy Fails to Provide Long-Term Protection Against Ischemic Stroke. Aging and Disease. 9: 467-479. PMID 29896434 DOI: 10.14336/AD.2018.0130 |
0.308 |
|
| 2018 |
Zhang R, Zhang W, Stetler RA, Hu X, Chen J, Gao Y. Abstract WP250: Evaluating & Optimizing the Model of Thrombotic MCAO in Mice Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wp250 |
0.338 |
|
| 2018 |
Dai X, Zhao J, Xu F, Cai W, Chen J, Hu X. Abstract TMP27: Tgfalpha Protects Oligodendrocytes Against Ischemic Injury and Promotes White Matter Integrity After Stroke Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Tmp27 |
0.384 |
|
| 2017 |
Cai W, Yang T, Liu H, Han L, Zhang K, Hu X, Zhang X, Yin KJ, Gao Y, Bennett MVL, Leak RK, Chen J. Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair. Progress in Neurobiology. PMID 29032144 DOI: 10.1016/J.Pneurobio.2017.10.002 |
0.415 |
|
| 2017 |
Liu Z, Ran Y, Huang S, Wen S, Zhang W, Liu X, Ji Z, Geng X, Ji X, Du H, Leak RK, Hu X. Curcumin Protects against Ischemic Stroke by Titrating Microglia/Macrophage Polarization. Frontiers in Aging Neuroscience. 9: 233. PMID 28785217 DOI: 10.3389/Fnagi.2017.00233 |
0.43 |
|
| 2017 |
Li P, Wang L, Zhou Y, Gan Y, Zhu W, Xia Y, Jiang X, Watkins S, Vazquez A, Thomson AW, Chen J, Yu W, Hu X. C-C Chemokine Receptor Type 5 (CCR5)-Mediated Docking of Transferred Tregs Protects Against Early Blood-Brain Barrier Disruption After Stroke. Journal of the American Heart Association. 6. PMID 28768648 DOI: 10.1161/Jaha.117.006387 |
0.401 |
|
| 2017 |
Mao L, Li P, Zhu W, Cai W, Liu Z, Wang Y, Luo W, Stetler RA, Leak RK, Yu W, Gao Y, Chen J, Chen G, Hu X. Regulatory T cells ameliorate tissue plasminogen activator-induced brain haemorrhage after stroke. Brain : a Journal of Neurology. PMID 28535201 DOI: 10.1093/Brain/Awx111 |
0.419 |
|
| 2017 |
Yang Y, Liu H, Zhang H, Ye Q, Wang J, Yang B, Mao L, Zhu W, Leak RK, Xiao B, Lu B, Chen J, Hu X. ST2/IL-33-Dependent Microglial Response Limits Acute Ischemic Brain Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28389473 DOI: 10.1523/Jneurosci.3233-16.2017 |
0.424 |
|
| 2017 |
Hu X, De Silva TM, Chen J, Faraci FM. Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke. Circulation Research. 120: 449-471. PMID 28154097 DOI: 10.1161/Circresaha.116.308427 |
0.412 |
|
| 2017 |
Shi Y, Jiang X, Zhang L, Pu H, Hu X, Zhang W, Cai W, Gao Y, Leak RK, Keep RF, Bennett MV, Chen J. Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood-brain barrier disruption after ischemic brain injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137866 DOI: 10.1073/Pnas.1621174114 |
0.422 |
|
| 2016 |
Liu H, Yang Y, Xia Y, Zhu W, Leak RK, Wei Z, Wang J, Hu X. Aging of Cerebral White Matter. Ageing Research Reviews. PMID 27865980 DOI: 10.1016/J.Arr.2016.11.006 |
0.374 |
|
| 2016 |
Cai W, Liu H, Zhao J, Chen LY, Chen J, Lu Z, Hu X. Pericytes in Brain Injury and Repair After Ischemic Stroke. Translational Stroke Research. PMID 27837475 DOI: 10.1007/S12975-016-0504-4 |
0.442 |
|
| 2016 |
Jiang X, Pu H, Hu X, Wei Z, Hong D, Zhang W, Gao Y, Chen J, Shi Y. A Post-stroke Therapeutic Regimen with Omega-3 Polyunsaturated Fatty Acids that Promotes White Matter Integrity and Beneficial Microglial Responses after Cerebral Ischemia. Translational Stroke Research. PMID 27714669 DOI: 10.1007/S12975-016-0502-6 |
0.411 |
|
| 2016 |
Cai W, Zhang K, Li P, Zhu L, Xu J, Yang B, Hu X, Lu Z, Chen J. Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: an aging effect. Ageing Research Reviews. PMID 27697546 DOI: 10.1016/J.Arr.2016.09.006 |
0.415 |
|
| 2016 |
Pu H, Jiang X, Hu X, Xia J, Hong D, Zhang W, Gao Y, Chen J, Shi Y. Delayed Docosahexaenoic Acid Treatment Combined with Dietary Supplementation of Omega-3 Fatty Acids Promotes Long-Term Neurovascular Restoration After Ischemic Stroke. Translational Stroke Research. PMID 27566736 DOI: 10.1007/S12975-016-0498-Y |
0.397 |
|
| 2016 |
An C, Jiang X, Pu H, Hong D, Zhang W, Hu X, Gao Y. Severity-Dependent Long-Term Spatial Learning-Memory Impairment in a Mouse Model of Traumatic Brain Injury. Translational Stroke Research. PMID 27539574 DOI: 10.1007/S12975-016-0483-5 |
0.317 |
|
| 2016 |
Xia Y, Cai W, Thomson AW, Hu X. Regulatory T Cell Therapy for Ischemic Stroke: how far from Clinical Translation? Translational Stroke Research. PMID 27307291 DOI: 10.1007/S12975-016-0476-4 |
0.332 |
|
| 2016 |
Stetler RA, Gao Y, Leak RK, Weng Z, Shi Y, Zhang L, Pu H, Zhang F, Hu X, Hassan S, Ferguson C, Homanics GE, Cao G, Bennett MV, Chen J. APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274063 DOI: 10.1073/Pnas.1606226113 |
0.419 |
|
| 2016 |
Zhang W, Zhang H, Mu H, Zhu W, Jiang X, Hu X, Shi Y, Leak RK, Dong Q, Chen J, Gao Y. Omega-3 polyunsaturated fatty acids mitigate blood-brain barrier disruption after hypoxic-ischemic brain injury. Neurobiology of Disease. PMID 26921472 DOI: 10.1016/J.Nbd.2016.02.020 |
0.358 |
|
| 2016 |
Shi Y, Zhang L, Pu H, Mao L, Hu X, Jiang X, Xu N, Stetler RA, Zhang F, Liu X, Leak RK, Keep RF, Ji X, Chen J. Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury. Nature Communications. 7: 10523. PMID 26813496 DOI: 10.1038/Ncomms10523 |
0.408 |
|
| 2016 |
Liu X, Liu J, Zhao S, Zhang H, Cai W, Cai M, Ji X, Leak RK, Gao Y, Chen J, Hu X. Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery After Cerebral Ischemia. Stroke; a Journal of Cerebral Circulation. PMID 26732561 DOI: 10.1161/Strokeaha.115.012079 |
0.388 |
|
| 2015 |
Zhang W, Liu J, Hu X, Li P, Leak RK, Gao Y, Chen J. n-3 Polyunsaturated Fatty Acids Reduce Neonatal Hypoxic/Ischemic Brain Injury by Promoting Phosphatidylserine Formation and Akt Signaling. Stroke; a Journal of Cerebral Circulation. PMID 26374481 DOI: 10.1161/Strokeaha.115.010815 |
0.377 |
|
| 2015 |
Han L, Cai W, Mao L, Liu J, Li P, Leak RK, Xu Y, Hu X, Chen J. Rosiglitazone Promotes White Matter Integrity and Long-Term Functional Recovery After Focal Cerebral Ischemia. Stroke; a Journal of Cerebral Circulation. PMID 26243225 DOI: 10.1161/Strokeaha.115.010091 |
0.373 |
|
| 2015 |
Suenaga J, Hu X, Pu H, Shi Y, Hassan SH, Xu M, Leak RK, Stetler RA, Gao Y, Chen J. White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke. Experimental Neurology. PMID 25836044 DOI: 10.1016/J.Expneurol.2015.03.021 |
0.399 |
|
| 2015 |
Shi H, Hu X, Leak RK, Shi Y, An C, Suenaga J, Chen J, Gao Y. Demyelination as a rational therapeutic target for ischemic or traumatic brain injury. Experimental Neurology. PMID 25819104 DOI: 10.1016/J.Expneurol.2015.03.017 |
0.411 |
|
| 2015 |
Zhang H, Li F, Yang Y, Chen J, Hu X. SIRP/CD47 signaling in neurological disorders. Brain Research. PMID 25795378 DOI: 10.1016/J.Brainres.2015.03.012 |
0.346 |
|
| 2015 |
Liesz A, Hu X, Kleinschnitz C, Offner H. Functional role of regulatory lymphocytes in stroke: facts and controversies. Stroke; a Journal of Cerebral Circulation. 46: 1422-30. PMID 25791715 DOI: 10.1161/Strokeaha.114.008608 |
0.325 |
|
| 2015 |
Zhang W, Wang H, Zhang H, Leak RK, Shi Y, Hu X, Gao Y, Chen J. Dietary supplementation with omega-3 polyunsaturated fatty acids robustly promotes neurovascular restorative dynamics and improves neurological functions after stroke. Experimental Neurology. PMID 25771800 DOI: 10.1016/J.Expneurol.2015.03.005 |
0.424 |
|
| 2015 |
Wang G, Shi Y, Jiang X, Leak RK, Hu X, Wu Y, Pu H, Li WW, Tang B, Wang Y, Gao Y, Zheng P, Bennett MV, Chen J. HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2853-8. PMID 25691750 DOI: 10.1073/Pnas.1501441112 |
0.355 |
|
| 2015 |
Shi H, Wang HL, Pu HJ, Shi YJ, Zhang J, Zhang WT, Wang GH, Hu XM, Leak RK, Chen J, Gao YQ. Ethyl pyruvate protects against blood-brain barrier damage and improves long-term neurological outcomes in a rat model of traumatic brain injury. Cns Neuroscience & Therapeutics. 21: 374-84. PMID 25533312 DOI: 10.1111/Cns.12366 |
0.387 |
|
| 2015 |
Liu ZJ, Chen C, Li FW, Shen JM, Yang YY, Leak RK, Ji XM, Du HS, Hu XM. Splenic responses in ischemic stroke: new insights into stroke pathology. Cns Neuroscience & Therapeutics. 21: 320-6. PMID 25475834 DOI: 10.1111/Cns.12361 |
0.436 |
|
| 2015 |
Hu X, Leak RK, Shi Y, Suenaga J, Gao Y, Zheng P, Chen J. Microglial and macrophage polarization—new prospects for brain repair. Nature Reviews. Neurology. 11: 56-64. PMID 25385337 DOI: 10.1038/Nrneurol.2014.207 |
0.393 |
|
| 2014 |
Chen S, Zhang H, Pu H, Wang G, Li W, Leak RK, Chen J, Liou AK, Hu X. n-3 PUFA supplementation benefits microglial responses to myelin pathology. Scientific Reports. 4: 7458. PMID 25500548 DOI: 10.1038/Srep07458 |
0.309 |
|
| 2014 |
Zhao S, Li F, Leak RK, Chen J, Hu X. Regulation of Neuroinflammation through Programed Death-1/Programed Death Ligand Signaling in Neurological Disorders. Frontiers in Cellular Neuroscience. 8: 271. PMID 25232304 DOI: 10.3389/Fncel.2014.00271 |
0.324 |
|
| 2014 |
Hu X, Liou AK, Leak RK, Xu M, An C, Suenaga J, Shi Y, Gao Y, Zheng P, Chen J. Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles. Progress in Neurobiology. 119: 60-84. PMID 24923657 DOI: 10.1016/J.Pneurobio.2014.06.002 |
0.344 |
|
| 2014 |
Wang J, Shi Y, Zhang L, Zhang F, Hu X, Zhang W, Leak RK, Gao Y, Chen L, Chen J. Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke. Neurobiology of Disease. 68: 91-103. PMID 24794156 DOI: 10.1016/J.Nbd.2014.04.014 |
0.418 |
|
| 2014 |
Li P, Mao L, Liu X, Gan Y, Zheng J, Thomson AW, Gao Y, Chen J, Hu X. Essential role of program death 1-ligand 1 in regulatory T-cell-afforded protection against blood-brain barrier damage after stroke. Stroke; a Journal of Cerebral Circulation. 45: 857-64. PMID 24496394 DOI: 10.1161/Strokeaha.113.004100 |
0.427 |
|
| 2014 |
Zhang M, Wang S, Mao L, Leak RK, Shi Y, Zhang W, Hu X, Sun B, Cao G, Gao Y, Xu Y, Chen J, Zhang F. Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1903-15. PMID 24478369 DOI: 10.1523/Jneurosci.4043-13.2014 |
0.403 |
|
| 2014 |
Stetler RA, Leak RK, Gan Y, Li P, Zhang F, Hu X, Jing Z, Chen J, Zigmond MJ, Gao Y. Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance. Progress in Neurobiology. 114: 58-83. PMID 24389580 DOI: 10.1016/J.Pneurobio.2013.11.005 |
0.434 |
|
| 2014 |
An C, Shi Y, Li P, Hu X, Gan Y, Stetler RA, Leak RK, Gao Y, Sun BL, Zheng P, Chen J. Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair. Progress in Neurobiology. 115: 6-24. PMID 24374228 DOI: 10.1016/J.Pneurobio.2013.12.002 |
0.431 |
|
| 2014 |
Hu X, Zhang F, Leak RK, Zhang W, Iwai M, Stetler RA, Dai Y, Zhao A, Gao Y, Chen J. Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke. Current Molecular Medicine. 13: 1465-73. PMID 23971733 DOI: 10.2174/15665240113139990075 |
0.419 |
|
| 2013 |
Li P, Mao L, Zhou G, Leak RK, Sun BL, Chen J, Hu X. Adoptive regulatory T-cell therapy preserves systemic immune homeostasis after cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 44: 3509-15. PMID 24092548 DOI: 10.1161/Strokeaha.113.002637 |
0.351 |
|
| 2013 |
Wang G, Zhang J, Hu X, Zhang L, Mao L, Jiang X, Liou AK, Leak RK, Gao Y, Chen J. Microglia/macrophage polarization dynamics in white matter after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1864-74. PMID 23942366 DOI: 10.1038/Jcbfm.2013.146 |
0.348 |
|
| 2013 |
Hu X, Li P, Chen J. Pro: Regulatory T cells are protective in ischemic stroke. Stroke; a Journal of Cerebral Circulation. 44: e85-6. PMID 23821231 DOI: 10.1161/Strokeaha.113.001267 |
0.443 |
|
| 2013 |
Li P, Gan Y, Sun BL, Zhang F, Lu B, Gao Y, Liang W, Thomson AW, Chen J, Hu X. Adoptive regulatory T-cell therapy protects against cerebral ischemia. Annals of Neurology. 74: 458-71. PMID 23674483 DOI: 10.1002/Ana.23815 |
0.419 |
|
| 2013 |
Wang G, Jiang X, Pu H, Zhang W, An C, Hu X, Liou AK, Leak RK, Gao Y, Chen J. Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 10: 124-42. PMID 23132328 DOI: 10.1007/S13311-012-0157-2 |
0.353 |
|
| 2012 |
Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, Gao Y, Chen J. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 43: 3063-70. PMID 22933588 DOI: 10.1161/Strokeaha.112.659656 |
0.402 |
|
| 2012 |
Hu X, Zhang M, Leak RK, Gan Y, Li P, Gao Y, Chen J. Delivery of neurotherapeutics across the blood brain barrier in stroke. Current Pharmaceutical Design. 18: 3704-20. PMID 22574984 DOI: 10.2174/138161212802002715 |
0.413 |
|
| 2012 |
Stetler RA, Gao Y, Zhang L, Weng Z, Zhang F, Hu X, Wang S, Vosler P, Cao G, Sun D, Graham SH, Chen J. Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2667-82. PMID 22357851 DOI: 10.1523/Jneurosci.5169-11.2012 |
0.312 |
|
| 2012 |
Gan Y, Ji X, Hu X, Luo Y, Zhang L, Li P, Liu X, Yan F, Vosler P, Gao Y, Stetler RA, Chen J. Transgenic overexpression of peroxiredoxin-2 attenuates ischemic neuronal injury via suppression of a redox-sensitive pro-death signaling pathway. Antioxidants & Redox Signaling. 17: 719-32. PMID 22356734 DOI: 10.1089/Ars.2011.4298 |
0.368 |
|
| 2012 |
Chu M, Hu X, Lu S, Gan Y, Li P, Guo Y, Zhang J, Chen J, Gao Y. Focal cerebral ischemia activates neurovascular restorative dynamics in mouse brain. Frontiers in Bioscience (Elite Edition). 4: 1926-36. PMID 22202008 DOI: 10.2741/513 |
0.425 |
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| 2012 |
Hu X, Zhou H, Zhang D, Yang S, Qian L, Wu HM, Chen PS, Wilson B, Gao HM, Lu RB, Hong JS. Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 187-201. PMID 21870076 DOI: 10.1007/S11481-011-9309-0 |
0.341 |
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| 2012 |
Niu FN, Zhang X, Hu XM, Chen J, Chang LL, Li JW, Liu Z, Cao W, Xu Y. Targeted mutation of Fas ligand gene attenuates brain inflammation in experimental stroke. Brain, Behavior, and Immunity. 26: 61-71. PMID 21802508 DOI: 10.1016/J.Bbi.2011.07.235 |
0.473 |
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| 2011 |
Zhang W, Li P, Hu X, Zhang F, Chen J, Gao Y. Omega-3 polyunsaturated fatty acids in the brain: metabolism and neuroprotection. Frontiers in Bioscience (Landmark Edition). 16: 2653-70. PMID 21622201 DOI: 10.2741/3878 |
0.332 |
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| 2011 |
Zhang D, Hu X, Qian L, Chen SH, Zhou H, Wilson B, Miller DS, Hong JS. Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity. Journal of Neuroinflammation. 8: 3. PMID 21232086 DOI: 10.1186/1742-2094-8-3 |
0.328 |
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| 2011 |
Li P, Hu X, Gan Y, Gao Y, Liang W, Chen J. Mechanistic insight into DNA damage and repair in ischemic stroke: exploiting the base excision repair pathway as a model of neuroprotection. Antioxidants & Redox Signaling. 14: 1905-18. PMID 20677909 DOI: 10.1089/Ars.2010.3451 |
0.355 |
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| 2010 |
Zhang W, Hu X, Yang W, Gao Y, Chen J. Omega-3 polyunsaturated fatty acid supplementation confers long-term neuroprotection against neonatal hypoxic-ischemic brain injury through anti-inflammatory actions. Stroke; a Journal of Cerebral Circulation. 41: 2341-7. PMID 20705927 DOI: 10.1161/Strokeaha.110.586081 |
0.366 |
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| 2010 |
Iwai M, Stetler RA, Xing J, Hu X, Gao Y, Zhang W, Chen J, Cao G. Enhanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury. Stroke; a Journal of Cerebral Circulation. 41: 1032-7. PMID 20360553 DOI: 10.1161/Strokeaha.109.570325 |
0.427 |
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| 2010 |
Zhang D, Hu X, Qian L, O'Callaghan JP, Hong JS. Astrogliosis in CNS pathologies: is there a role for microglia? Molecular Neurobiology. 41: 232-41. PMID 20148316 DOI: 10.1007/S12035-010-8098-4 |
0.378 |
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| 2010 |
Shen H, Hu X, Liu C, Wang S, Zhang W, Gao H, Stetler RA, Gao Y, Chen J. Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms. Neurobiology of Disease. 37: 711-22. PMID 20026271 DOI: 10.1016/J.Nbd.2009.12.010 |
0.432 |
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| 2010 |
Gao Y, Liang W, Hu X, Zhang W, Stetler RA, Vosler P, Cao G, Chen J. Neuroprotection against hypoxic-ischemic brain injury by inhibiting the apoptotic protease activating factor-1 pathway. Stroke; a Journal of Cerebral Circulation. 41: 166-72. PMID 19910549 DOI: 10.1161/Strokeaha.109.561852 |
0.407 |
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| 2009 |
Wu HM, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB. Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2344-57. PMID 19536110 DOI: 10.1038/Npp.2009.64 |
0.337 |
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| 2009 |
Zhang D, Hu X, Qian L, Wilson B, Lee C, Flood P, Langenbach R, Hong JS. Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro. Toxicology and Applied Pharmacology. 238: 64-70. PMID 19397918 DOI: 10.1016/J.Taap.2009.04.015 |
0.327 |
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| 2009 |
Qian L, Hu X, Zhang D, Snyder A, Wu HM, Li Y, Wilson B, Lu RB, Hong JS, Flood PM. beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway. Glia. 57: 1600-9. PMID 19330844 DOI: 10.1002/Glia.20873 |
0.322 |
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| 2009 |
Li Y, Hu X, Liu Y, Bao Y, An L. Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. Neuropharmacology. 56: 580-9. PMID 19049811 DOI: 10.1016/J.Neuropharm.2008.10.016 |
0.345 |
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| 2008 |
Hu X, Zhang D, Pang H, Caudle WM, Li Y, Gao H, Liu Y, Qian L, Wilson B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS. Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7194-204. PMID 18981141 DOI: 10.4049/Jimmunol.181.10.7194 |
0.328 |
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| 2008 |
Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS. Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity. Journal of Neuroinflammation. 5: 21. PMID 18507839 DOI: 10.1186/1742-2094-5-21 |
0.342 |
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| 2008 |
Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS. Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration? Environmental Health Perspectives. 116: 593-8. PMID 18470306 DOI: 10.1289/Ehp.11031 |
0.318 |
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| 2008 |
Yang S, Zhang D, Yang Z, Hu X, Qian S, Liu J, Wilson B, Block M, Hong JS. Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture. Neurochemical Research. 33: 2044-53. PMID 18368483 DOI: 10.1007/S11064-008-9675-Z |
0.335 |
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| 2006 |
Hu X, Rea HC, Wiktorowicz JE, Perez-Polo JR. Proteomic analysis of hypoxia/ischemia-induced alteration of cortical development and dopamine neurotransmission in neonatal rat. Journal of Proteome Research. 5: 2396-404. PMID 16944952 DOI: 10.1021/Pr060209X |
0.567 |
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| 2005 |
Hu X, Nesic-Taylor O, Qiu J, Rea HC, Fabian R, Rassin DK, Perez-Polo JR. Activation of nuclear factor-kappaB signaling pathway by interleukin-1 after hypoxia/ischemia in neonatal rat hippocampus and cortex. Journal of Neurochemistry. 93: 26-37. PMID 15773902 DOI: 10.1111/J.1471-4159.2004.02968.X |
0.68 |
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| 2004 |
Qiu J, Hu X, Nesic O, Grafe MR, Rassin DK, Wood TG, Perez-Polo JR. Effects of NF-kappaB oligonucleotide "decoys" on gene expression in P7 rat hippocampus after hypoxia/ischemia. Journal of Neuroscience Research. 77: 108-18. PMID 15197744 DOI: 10.1002/Jnr.20156 |
0.662 |
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| 2003 |
Hu X, Qiu J, Grafe MR, Rea HC, Rassin DK, Perez-Polo JR. Bcl-2 family members make different contributions to cell death in hypoxia and/or hyperoxia in rat cerebral cortex. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 21: 371-7. PMID 14599483 DOI: 10.1016/S0736-5748(03)00089-3 |
0.681 |
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