| Year |
Citation |
Score |
| 2024 |
Bertrand BP, Shinde D, Thomas VC, Whiteley M, Ibberson CB, Kielian T. Metabolic diversity of human macrophages: potential influence on intracellular survival. Infection and Immunity. e0047423. PMID 38179975 DOI: 10.1128/iai.00474-23 |
0.319 |
|
| 2023 |
Van Roy Z, Shi W, Kak G, Duan B, Kielian T. Epigenetic Regulation of Leukocyte Inflammatory Mediator Production Dictates Staphylococcus aureus Craniotomy Infection Outcome. Journal of Immunology (Baltimore, Md. : 1950). PMID 37314520 DOI: 10.4049/jimmunol.2300050 |
0.37 |
|
| 2023 |
Kak G, Van Roy Z, Heim CE, Fallet RW, Shi W, Roers A, Duan B, Kielian T. IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection. Journal of Neuroinflammation. 20: 114. PMID 37179295 DOI: 10.1186/s12974-023-02798-7 |
0.36 |
|
| 2021 |
Korshoj LE, Shi W, Duan B, Kielian T. The Prospect of Nanoparticle Systems for Modulating Immune Cell Polarization During Central Nervous System Infection. Frontiers in Immunology. 12: 670931. PMID 34248952 DOI: 10.3389/fimmu.2021.670931 |
0.308 |
|
| 2021 |
de Morais SD, Kak G, Menousek JP, Kielian T. Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm. Frontiers in Immunology. 12: 625467. PMID 33708216 DOI: 10.3389/fimmu.2021.625467 |
0.339 |
|
| 2020 |
Vadukoot AK, Sharma S, Aretz CD, Kumar S, Gautam N, Alnouti Y, Aldrich AL, Heim CE, Kielian T, Hopkins CR. Synthesis and SAR Studies of 1-Pyrrolo[2,3-]pyridine-2-carboxamides as Phosphodiesterase 4B (PDE4B) Inhibitors. Acs Medicinal Chemistry Letters. 11: 1848-1854. PMID 33062163 DOI: 10.1021/Acsmedchemlett.9B00369 |
0.314 |
|
| 2020 |
Bosch ME, Bertrand BP, Heim CE, Alqarzaee AA, Chaudhari SS, Aldrich AL, Fey PD, Thomas VC, Kielian T. Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity. Mbio. 11. PMID 32900803 DOI: 10.1128/Mbio.01581-20 |
0.482 |
|
| 2020 |
Heim CE, Bosch ME, Yamada KJ, Aldrich AL, Chaudhari SS, Klinkebiel D, Gries CM, Alqarzaee AA, Li Y, Thomas VC, Seto E, Karpf AR, Kielian T. Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection. Nature Microbiology. PMID 32661313 DOI: 10.1038/S41564-020-0756-3 |
0.454 |
|
| 2020 |
Heim CE, Yamada KJ, Fallet R, Odvody J, Schwarz DM, Lyden ER, Anderson MJ, Alter R, Vidlak D, Hartman CW, Konigsberg BS, Cornett CA, Garvin KL, Mohamed N, Anderson AS, ... Kielian T, et al. Orthopaedic Surgery Elicits a Systemic Anti-Inflammatory Signature. Journal of Clinical Medicine. 9. PMID 32640676 DOI: 10.3390/Jcm9072123 |
0.416 |
|
| 2020 |
Aldrich AL, Heim CE, Shi W, Fallet RW, Duan B, Kielian T. TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection. Journal of Neuroinflammation. 17: 114. PMID 32290861 DOI: 10.1186/s12974-020-01793-6 |
0.372 |
|
| 2019 |
Skar GL, Beaver M, Aldrich A, Lagundzin D, Thapa I, Woods N, Ali H, Snowden J, Kielian T. Identification of potential cerebrospinal fluid (CSF) biomarkers to discriminate between infection and sterile inflammation in a rat model of catheter infection. Infection and Immunity. PMID 31262978 DOI: 10.1128/Iai.00311-19 |
0.38 |
|
| 2019 |
Aldrich A, Kuss MA, Duan B, Kielian T. 3D Bioprinted Scaffolds Containing Viable Macrophages and Antibiotics Promote Clearance of Staphylococcus aureus Craniotomy-Associated Biofilm Infection. Acs Applied Materials & Interfaces. 11: 12298-12307. PMID 30855125 DOI: 10.1021/Acsami.9B00264 |
0.345 |
|
| 2019 |
Zhang W, Guo Y, Kuss M, Shi W, Aldrich A, Untrauer J, Kielian T, Duan B. Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation. Tissue Engineering. Part B, Reviews. PMID 30712506 DOI: 10.1089/Ten.Teb.2018.0309 |
0.318 |
|
| 2019 |
Zhou C, Bhinderwala F, Lehman MK, Thomas VC, Chaudhari SS, Yamada KJ, Foster KW, Powers R, Kielian T, Fey PD. Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection. Plos Pathogens. 15: e1007538. PMID 30608981 DOI: 10.1371/Journal.Ppat.1007538 |
0.321 |
|
| 2019 |
Burkovetskaya M, Bosch ME, Karpuk N, Fallet R, Kielian T. Caspase 1 activity influences juvenile Batten disease (CLN3) pathogenesis. Journal of Neurochemistry. 148: 652-668. PMID 29873075 DOI: 10.1111/Jnc.14480 |
0.314 |
|
| 2018 |
Yamada KJ, Kielian T. Biofilm-Leukocyte Cross-Talk: Impact on Immune Polarization and Immunometabolism. Journal of Innate Immunity. 11: 280-288. PMID 30347401 DOI: 10.1159/000492680 |
0.422 |
|
| 2018 |
Heim CE, West SC, Ali H, Kielian T. Heterogeneity of Ly6GLy6C myeloid-derived suppressor cell (MDSC) infiltrates during biofilm infection. Infection and Immunity. PMID 30249747 DOI: 10.1128/Iai.00684-18 |
0.391 |
|
| 2018 |
Yamada KJ, Heim CE, Aldrich AL, Gries CM, Staudacher AG, Kielian T. Arginase-1 Expression in Myeloid Cells Regulates Staphylococcus aureus Planktonic but Not Biofilm Infection. Infection and Immunity. 86. PMID 29661929 DOI: 10.1128/Iai.00206-18 |
0.427 |
|
| 2017 |
Heim CE, Vidlak D, Odvody J, Hartman CW, Garvin KL, Kielian T. Human prosthetic joint infections are associated with myeloid-derived suppressor cells (MDSCs): implications for infection persistence. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29139571 DOI: 10.1002/Jor.23806 |
0.44 |
|
| 2017 |
Mashruwala AA, Gries CM, Scherr TD, Kielian T, Boyd JM. SaeRS is responsive to cellular respiratory status and regulates fermentative biofilm formation in Staphylococcus aureus. Infection and Immunity. PMID 28507069 DOI: 10.1128/Iai.00157-17 |
0.353 |
|
| 2017 |
Gries CM, Kielian T. Staphylococcal Biofilms and Immune Polarization During Prosthetic Joint Infection. The Journal of the American Academy of Orthopaedic Surgeons. S20-S24. PMID 27922945 DOI: 10.5435/Jaaos-D-16-00636 |
0.417 |
|
| 2016 |
Gries CM, Bruger EL, Moormeier DE, Scherr TD, Waters CM, Kielian T. Cyclic di-AMP released from Staphylococcus aureus biofilm induces a macrophage type I interferon response. Infection and Immunity. PMID 27736778 DOI: 10.1128/Iai.00447-16 |
0.416 |
|
| 2016 |
Bosch ME, Aldrich A, Fallet R, Odvody J, Burkovetskaya M, Schuberth K, Fitzgerald JA, Foust KD, Kielian T. Self-Complementary AAV9 Gene Delivery Partially Corrects Pathology Associated with Juvenile Neuronal Ceroid Lipofuscinosis (CLN3). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9669-82. PMID 27629717 DOI: 10.1523/Jneurosci.1635-16.2016 |
0.322 |
|
| 2016 |
Vidlak D, Kielian T. Infectious Dose Dictates the Host Response during Staphylococcus aureus Orthopedic-Implant Biofilm Infection. Infection and Immunity. 84: 1957-1965. PMID 27091926 DOI: 10.1128/Iai.00117-16 |
0.441 |
|
| 2016 |
Yajjala VK, Thomas VC, Bauer C, Scherr TD, Fischer KJ, Fey PD, Bayles KW, Kielian T, Sun K. Resistance to Acute Macrophage Killing Promotes Airway Fitness of Prevalent Community-Acquired Staphylococcus aureus Strains. Journal of Immunology (Baltimore, Md. : 1950). PMID 27053759 DOI: 10.4049/Jimmunol.1600081 |
0.372 |
|
| 2015 |
Bosch ME, Kielian T. Neuroinflammatory paradigms in lysosomal storage diseases. Frontiers in Neuroscience. 9: 417. PMID 26578874 DOI: 10.3389/Fnins.2015.00417 |
0.354 |
|
| 2015 |
Rama Rao KV, Kielian T. Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammation. Clinical & Experimental Neuroimmunology. 6: 245-263. PMID 26543505 DOI: 10.1111/Cen3.12237 |
0.302 |
|
| 2015 |
Poole JA, Wyatt TA, Romberger DJ, Staab E, Simet S, Reynolds SJ, Sisson JH, Kielian T. MyD88 in lung resident cells governs airway inflammatory and pulmonary function responses to organic dust treatment. Respiratory Research. 16: 111. PMID 26376975 DOI: 10.1186/S12931-015-0272-9 |
0.362 |
|
| 2015 |
Scherr TD, Hanke ML, Huang O, James DB, Horswill AR, Bayles KW, Fey PD, Torres VJ, Kielian T. Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. Mbio. 6. PMID 26307164 DOI: 10.1128/Mbio.01021-15 |
0.383 |
|
| 2015 |
Heim CE, Vidlak D, Kielian T. Interleukin-10 production by myeloid-derived suppressor cells contributes to bacterial persistence during Staphylococcus aureus orthopedic biofilm infection. Journal of Leukocyte Biology. PMID 26232453 DOI: 10.1189/Jlb.4Vma0315-125Rr |
0.46 |
|
| 2015 |
Heim CE, Vidlak D, Scherr TD, Hartman CW, Garvin KL, Kielian T. IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection. Journal of Immunology (Baltimore, Md. : 1950). 194: 3861-72. PMID 25762781 DOI: 10.4049/Jimmunol.1402689 |
0.498 |
|
| 2015 |
Mootz JM, Benson MA, Heim CE, Crosby HA, Kavanaugh JS, Dunman PM, Kielian T, Torres VJ, Horswill AR. Rot is a key regulator of Staphylococcus aureus biofilm formation. Molecular Microbiology. 96: 388-404. PMID 25612137 DOI: 10.1111/Mmi.12943 |
0.343 |
|
| 2014 |
Wang G, Hanke ML, Mishra B, Lushnikova T, Heim CE, Chittezham Thomas V, Bayles KW, Kielian T. Transformation of human cathelicidin LL-37 into selective, stable, and potent antimicrobial compounds. Acs Chemical Biology. 9: 1997-2002. PMID 25061850 DOI: 10.1021/Cb500475Y |
0.309 |
|
| 2014 |
Kielian T. Neuroinflammation: good, bad, or indifferent? Journal of Neurochemistry. 130: 1-3. PMID 24861635 DOI: 10.1111/Jnc.12755 |
0.452 |
|
| 2014 |
Burkovetskaya M, Karpuk N, Xiong J, Bosch M, Boska MD, Takeuchi H, Suzumura A, Kielian T. Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL). Plos One. 9: e95023. PMID 24736558 DOI: 10.1371/Journal.Pone.0095023 |
0.357 |
|
| 2014 |
Heim CE, Vidlak D, Scherr TD, Kozel JA, Holzapfel M, Muirhead DE, Kielian T. Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 3778-92. PMID 24646737 DOI: 10.4049/Jimmunol.1303408 |
0.461 |
|
| 2014 |
Scherr TD, Heim CE, Morrison JM, Kielian T. Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity. Frontiers in Immunology. 5: 37. PMID 24550921 DOI: 10.3389/Fimmu.2014.00037 |
0.383 |
|
| 2014 |
Hanamsagar R, Aldrich A, Kielian T. Critical role for the AIM2 inflammasome during acute CNS bacterial infection. Journal of Neurochemistry. 129: 704-11. PMID 24484406 DOI: 10.1111/Jnc.12669 |
0.756 |
|
| 2014 |
Heim CE, Hanke ML, Kielian T. A mouse model of Staphylococcus catheter-associated biofilm infection. Methods in Molecular Biology (Clifton, N.J.). 1106: 183-91. PMID 24222467 DOI: 10.1007/978-1-62703-736-5_17 |
0.389 |
|
| 2014 |
Scherr TD, Lindgren KE, Schaeffer CR, Hanke ML, Hartman CW, Kielian T. Mouse model of post-arthroplasty Staphylococcus epidermidis joint infection. Methods in Molecular Biology (Clifton, N.J.). 1106: 173-81. PMID 24222466 DOI: 10.1007/978-1-62703-736-5_16 |
0.331 |
|
| 2014 |
Hanamsagar R, Cardona SM, Kielian T, Cardona AE. Roles in immune responses Microglia in Health and Disease. 115-144. DOI: 10.1007/978-1-4939-1429-6_5 |
0.747 |
|
| 2013 |
Snowden JN, Beaver M, Beenken K, Smeltzer M, Horswill AR, Kielian T. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation. Plos One. 8: e84089. PMID 24386336 DOI: 10.1371/Journal.Pone.0084089 |
0.469 |
|
| 2013 |
Scherr TD, Roux CM, Hanke ML, Angle A, Dunman PM, Kielian T. Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells. Infection and Immunity. 81: 4363-76. PMID 24042108 DOI: 10.1128/Iai.00819-13 |
0.404 |
|
| 2013 |
Xiong J, Kielian T. Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype Journal of Neurochemistry. 127: 245-258. PMID 23919525 DOI: 10.1111/Jnc.12385 |
0.41 |
|
| 2013 |
Cheatle J, Aldrich A, Thorell WE, Boska MD, Kielian T. Compartmentalization of immune responses during Staphylococcus aureus cranial bone flap infection. The American Journal of Pathology. 183: 450-8. PMID 23747950 DOI: 10.1016/J.Ajpath.2013.04.031 |
0.37 |
|
| 2013 |
Bauer C, Kielian T, Wyatt TA, Romberger DJ, West WW, Gleason AM, Poole JA. Myeloid differentiation factor 88-dependent signaling is critical for acute organic dust-induced airway inflammation in mice. American Journal of Respiratory Cell and Molecular Biology. 48: 781-9. PMID 23492189 DOI: 10.1165/Rcmb.2012-0479Oc |
0.456 |
|
| 2013 |
Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T. Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections. Journal of Immunology (Baltimore, Md. : 1950). 190: 2159-68. PMID 23365077 DOI: 10.4049/Jimmunol.1202348 |
0.406 |
|
| 2013 |
Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T. Targeting macrophage activation for the prevention and treatment of Staphylococcus aureus biofilm infections (Journal of Immunology (2013) 190, (2159-2168)) Journal of Immunology. 190: 6709-6710. DOI: 10.4049/Jimmunol.1390029 |
0.364 |
|
| 2012 |
Nuxoll AS, Halouska SM, Sadykov MR, Hanke ML, Bayles KW, Kielian T, Powers R, Fey PD. CcpA regulates arginine biosynthesis in Staphylococcus aureus through repression of proline catabolism. Plos Pathogens. 8: e1003033. PMID 23209408 DOI: 10.1371/Journal.Ppat.1003033 |
0.304 |
|
| 2012 |
Poole JA, Gleason AM, Bauer C, West WW, Alexis N, Reynolds SJ, Romberger DJ, Kielian T. αβ T cells and a mixed Th1/Th17 response are important in organic dust-induced airway disease. Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology. 109: 266-273.e2. PMID 23010233 DOI: 10.1016/J.Anai.2012.06.015 |
0.314 |
|
| 2012 |
Hanke ML, Kielian T. Deciphering mechanisms of staphylococcal biofilm evasion of host immunity. Frontiers in Cellular and Infection Microbiology. 2: 62. PMID 22919653 DOI: 10.3389/Fcimb.2012.00062 |
0.439 |
|
| 2012 |
Hanke ML, Angle A, Kielian T. MyD88-dependent signaling influences fibrosis and alternative macrophage activation during Staphylococcus aureus biofilm infection. Plos One. 7: e42476. PMID 22879997 DOI: 10.1371/Journal.Pone.0042476 |
0.517 |
|
| 2012 |
Poole JA, Gleason AM, Bauer C, West WW, Alexis N, van Rooijen N, Reynolds SJ, Romberger DJ, Kielian TL. CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation. American Journal of Respiratory Cell and Molecular Biology. 47: 652-9. PMID 22822029 DOI: 10.1165/Rcmb.2012-0095Oc |
0.362 |
|
| 2012 |
Snowden JN, Beaver M, Smeltzer MS, Kielian T. Biofilm-infected intracerebroventricular shunts elicit inflammation within the central nervous system. Infection and Immunity. 80: 3206-14. PMID 22753376 DOI: 10.1128/Iai.00645-12 |
0.444 |
|
| 2012 |
Vidlak D, Kielian T. Differential effects of interleukin-17 receptor signaling on innate and adaptive immunity during central nervous system bacterial infection. Journal of Neuroinflammation. 9: 128. PMID 22704602 DOI: 10.1186/1742-2094-9-128 |
0.44 |
|
| 2012 |
Hanamsagar R, Hanke ML, Kielian T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends in Immunology. 33: 333-42. PMID 22521509 DOI: 10.1016/J.It.2012.03.001 |
0.758 |
|
| 2012 |
Karpuk N, Burkovetskaya M, Kielian T. Neuroinflammation alters voltage-dependent conductance in striatal astrocytes. Journal of Neurophysiology. 108: 112-23. PMID 22457466 DOI: 10.1152/Jn.01182.2011 |
0.301 |
|
| 2012 |
Xiong J, Burkovetskaya M, Karpuk N, Kielian T. IL-1RI (interleukin-1 receptor type I) signalling is essential for host defence and hemichannel activity during acute central nervous system bacterial infection. Asn Neuro. 4. PMID 22414156 DOI: 10.1042/An20120008 |
0.51 |
|
| 2012 |
Holley MM, Kielian T. Th1 and Th17 cells regulate innate immune responses and bacterial clearance during central nervous system infection. Journal of Immunology (Baltimore, Md. : 1950). 188: 1360-70. PMID 22190181 DOI: 10.4049/Jimmunol.1101660 |
0.473 |
|
| 2012 |
Holley MM, Zhang Y, Lehrmann E, Wood WH, Becker KG, Kielian T. Toll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia. Glia. 60: 29-42. PMID 21901759 DOI: 10.1002/Glia.21243 |
0.454 |
|
| 2011 |
Aldrich A, Kielian T. Central nervous system fibrosis is associated with fibrocyte-like infiltrates. The American Journal of Pathology. 179: 2952-62. PMID 22015460 DOI: 10.1016/J.Ajpath.2011.08.036 |
0.347 |
|
| 2011 |
Hanamsagar R, Torres V, Kielian T. Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia. Journal of Neurochemistry. 119: 736-48. PMID 21913925 DOI: 10.1111/J.1471-4159.2011.07481.X |
0.743 |
|
| 2011 |
Hanke ML, Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clinical Science (London, England : 1979). 121: 367-87. PMID 21745188 DOI: 10.1042/Cs20110164 |
0.476 |
|
| 2011 |
Poole JA, Kielian T, Wyatt TA, Gleason AM, Stone J, Palm K, West WW, Romberger DJ. Organic dust augments nucleotide-binding oligomerization domain expression via an NF-{kappa}B pathway to negatively regulate inflammatory responses. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L296-306. PMID 21665963 DOI: 10.1152/Ajplung.00086.2011 |
0.421 |
|
| 2011 |
Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, Williams SH, Engebretsen IL, Bayles KW, Horswill AR, Kielian T. Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 186: 6585-96. PMID 21525381 DOI: 10.4049/Jimmunol.1002794 |
0.469 |
|
| 2011 |
Liu S, Kielian T. MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection. Journal of Neuroinflammation. 8: 35. PMID 21496301 DOI: 10.1186/1742-2094-8-35 |
0.475 |
|
| 2011 |
Poole JA, Wyatt TA, Kielian T, Oldenburg P, Gleason AM, Bauer A, Golden G, West WW, Sisson JH, Romberger DJ. Toll-like receptor 2 regulates organic dust-induced airway inflammation. American Journal of Respiratory Cell and Molecular Biology. 45: 711-9. PMID 21278324 DOI: 10.1165/Rcmb.2010-0427Oc |
0.444 |
|
| 2011 |
Karpuk N, Burkovetskaya M, Fritz T, Angle A, Kielian T. Neuroinflammation leads to region-dependent alterations in astrocyte gap junction communication and hemichannel activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 414-25. PMID 21228152 DOI: 10.1523/Jneurosci.5247-10.2011 |
0.349 |
|
| 2011 |
Gurley C, Nichols J, Liu S, Phulwani NK, Esen N, Kielian T. Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-gamma Agonists. Ppar Research. 2008: 453120. PMID 18584038 DOI: 10.1155/2008/453120 |
0.458 |
|
| 2011 |
Poole J, Wyatt T, Kielian T, Oldenburg P, Gleason A, Bauer A, West W, Sisson J, Romberger D. Toll-like receptor (TLR2) Regulates Organic Dust-Induced Airway Inflammation Journal of Allergy and Clinical Immunology. 127: AB137-AB137. DOI: 10.1016/J.Jaci.2010.12.544 |
0.443 |
|
| 2010 |
Vidlak D, Mariani MM, Aldrich A, Liu S, Kielian T. Roles of Toll-like receptor 2 (TLR2) and superantigens on adaptive immune responses during CNS staphylococcal infection. Brain, Behavior, and Immunity. 25: 905-14. PMID 20868736 DOI: 10.1016/J.Bbi.2010.09.016 |
0.479 |
|
| 2010 |
Esen N, Kielian T. Toll-like receptors in brain abscess. Current Topics in Microbiology and Immunology. 336: 41-61. PMID 19688327 DOI: 10.1007/978-3-642-00549-7_3 |
0.497 |
|
| 2010 |
Kielian T. Overview of toll-like receptors in the CNS. Current Topics in Microbiology and Immunology. 336: 1-14. PMID 19688325 DOI: 10.1007/978-3-642-00549-7_1 |
0.421 |
|
| 2010 |
Poole J, Burrell A, Wyatt T, Kielian T, Romberger D. NOD2 Negatively Regulates Organic Dust-Induced Inflammation in Monocytes/Macrophages Journal of Allergy and Clinical Immunology. 125: AB118. DOI: 10.1016/J.Jaci.2009.12.467 |
0.346 |
|
| 2009 |
Liu S, Kielian T. Microglial activation by Citrobacter koseri is mediated by TLR4- and MyD88-dependent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 5537-47. PMID 19812209 DOI: 10.4049/Jimmunol.0900083 |
0.485 |
|
| 2009 |
Mariani MM, Kielian T. Microglia in infectious diseases of the central nervous system. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 448-61. PMID 19728102 DOI: 10.1007/S11481-009-9170-6 |
0.484 |
|
| 2009 |
Garg S, Nichols JR, Esen N, Liu S, Phulwani NK, Syed MM, Wood WH, Zhang Y, Becker KG, Aldrich A, Kielian T. MyD88 expression by CNS-resident cells is pivotal for eliciting protective immunity in brain abscesses. Asn Neuro. 1. PMID 19570030 DOI: 10.1042/An20090004 |
0.472 |
|
| 2009 |
Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T. TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses Journal of Immunology. 182: 7119-7130. PMID 19454709 DOI: 10.4049/Jimmunol.0802656 |
0.506 |
|
| 2008 |
Phulwani NK, Esen N, Syed MM, Kielian T. TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways. Journal of Immunology (Baltimore, Md. : 1950). 181: 3841-9. PMID 18768838 DOI: 10.4049/Jimmunol.181.6.3841 |
0.427 |
|
| 2008 |
Phulwani NK, Kielian T. Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation. Journal of Neurochemistry. 106: 578-90. PMID 18410506 DOI: 10.1111/J.1471-4159.2008.05403.X |
0.453 |
|
| 2008 |
Kielian T. Glial connexins and gap junctions in CNS inflammation and disease. Journal of Neurochemistry. 106: 1000-16. PMID 18410504 DOI: 10.1111/J.1471-4159.2008.05405.X |
0.365 |
|
| 2008 |
Kielian T, Syed MM, Liu S, Phulwani NK, Phillips N, Wagoner G, Drew PD, Esen N. The synthetic peroxisome proliferator-activated receptor-gamma agonist ciglitazone attenuates neuroinflammation and accelerates encapsulation in bacterial brain abscesses. Journal of Immunology (Baltimore, Md. : 1950). 180: 5004-16. PMID 18354226 DOI: 10.4049/Jimmunol.180.7.5004 |
0.466 |
|
| 2007 |
Syed MM, Phulwani NK, Kielian T. Tumor necrosis factor-alpha (TNF-alpha) regulates Toll-like receptor 2 (TLR2) expression in microglia. Journal of Neurochemistry. 103: 1461-71. PMID 17961202 DOI: 10.1111/J.1471-4159.2007.04838.X |
0.425 |
|
| 2007 |
Kielian T, Esen N, Liu S, Phulwani NK, Syed MM, Phillips N, Nishina K, Cheung AL, Schwartzman JD, Ruhe JJ. Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess. The American Journal of Pathology. 171: 1199-214. PMID 17717149 DOI: 10.2353/Ajpath.2007.070231 |
0.475 |
|
| 2007 |
Esen N, Kielian T. Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs). Journal of Neuroinflammation. 4: 10. PMID 17374157 DOI: 10.1186/1742-2094-4-10 |
0.359 |
|
| 2007 |
Kielian T, Phulwani NK, Esen N, Syed MM, Haney AC, McCastlain K, Johnson J. MyD88-dependent signals are essential for the host immune response in experimental brain abscess. Journal of Immunology (Baltimore, Md. : 1950). 178: 4528-37. PMID 17372011 DOI: 10.4049/Jimmunol.178.7.4528 |
0.517 |
|
| 2007 |
Esen N, Shuffield D, Syed MM, Kielian T. Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus. Glia. 55: 104-17. PMID 17029244 DOI: 10.1002/Glia.20438 |
0.376 |
|
| 2006 |
Phulwani NK, Feinstein DL, Gavrilyuk V, Akar C, Kielian T. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. Journal of Neurochemistry. 99: 1389-1402. PMID 17074064 DOI: 10.1111/J.1471-4159.2006.04183.X |
0.396 |
|
| 2006 |
Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. Journal of Neurochemistry. 99: 1-12. PMID 16899072 DOI: 10.1111/J.1471-4159.2006.04076.X |
0.437 |
|
| 2006 |
Esen N, Kielian T. Central role for MyD88 in the responses of microglia to pathogen-associated molecular patterns. Journal of Immunology (Baltimore, Md. : 1950). 176: 6802-11. PMID 16709840 DOI: 10.4049/Jimmunol.176.11.6802 |
0.486 |
|
| 2006 |
Kielian T. Toll-like receptors in central nervous system glial inflammation and homeostasis. Journal of Neuroscience Research. 83: 711-30. PMID 16541438 DOI: 10.1002/Jnr.20767 |
0.435 |
|
| 2005 |
Kielian T, Haney A, Mayes PM, Garg S, Esen N. Toll-like receptor 2 modulates the proinflammatory milieu in Staphylococcus aureus-induced brain abscess. Infection and Immunity. 73: 7428-35. PMID 16239543 DOI: 10.1128/Iai.73.11.7428-7435.2005 |
0.478 |
|
| 2005 |
Esen N, Kielian T. Recognition of Staphylococcus aureus-derived peptidoglycan (PGN) but not intact bacteria is mediated by CD14 in microglia. Journal of Neuroimmunology. 170: 93-104. PMID 16229899 DOI: 10.1016/J.Jneuroim.2005.09.003 |
0.352 |
|
| 2005 |
Garg S, Md Syed M, Kielian T. Staphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia. Journal of Neurochemistry. 95: 475-83. PMID 16190870 DOI: 10.1111/J.1471-4159.2005.03384.X |
0.387 |
|
| 2005 |
Kielian T, Esen N, Bearden ED. Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Glia. 49: 567-76. PMID 15593098 DOI: 10.1002/Glia.20144 |
0.465 |
|
| 2004 |
Kielian T. Immunopathogenesis of brain abscess. Journal of Neuroinflammation. 1: 16. PMID 15315708 DOI: 10.1186/1742-2094-1-16 |
0.42 |
|
| 2004 |
Kielian T, McMahon M, Bearden ED, Baldwin AC, Drew PD, Esen N. S. aureus-dependent microglial activation is selectively attenuated by the cyclopentenone prostaglandin 15-deoxy-Delta12,14- prostaglandin J2 (15d-PGJ2). Journal of Neurochemistry. 90: 1163-72. PMID 15312171 DOI: 10.1111/J.1471-4159.2004.02579.X |
0.421 |
|
| 2004 |
Baldwin AC, Kielian T. Persistent immune activation associated with a mouse model of Staphylococcus aureus-induced experimental brain abscess. Journal of Neuroimmunology. 151: 24-32. PMID 15145600 DOI: 10.1016/J.Jneuroim.2004.02.002 |
0.466 |
|
| 2004 |
Kielian T, Esen N. Effects of neuroinflammation on glia-glia gap junctional intercellular communication: a perspective. Neurochemistry International. 45: 429-36. PMID 15145557 DOI: 10.1016/J.Neuint.2003.09.010 |
0.384 |
|
| 2004 |
Kielian T, Bearden ED, Baldwin AC, Esen N. IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess. Journal of Neuropathology and Experimental Neurology. 63: 381-96. PMID 15099027 DOI: 10.1093/Jnen/63.4.381 |
0.476 |
|
| 2004 |
Kielian T. Microglia and chemokines in infectious diseases of the nervous system: views and reviews. Frontiers in Bioscience : a Journal and Virtual Library. 9: 732-50. PMID 14766404 DOI: 10.2741/1266 |
0.456 |
|
| 2004 |
Esen N, Tanga FY, DeLeo JA, Kielian T. Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. Journal of Neurochemistry. 88: 746-58. PMID 14720224 DOI: 10.1046/J.1471-4159.2003.02202.X |
0.476 |
|
| 2003 |
Kielian T, Drew PD. Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. Journal of Neuroscience Research. 71: 315-25. PMID 12526021 DOI: 10.1002/Jnr.10501 |
0.374 |
|
| 2002 |
Kielian T, Mayes P, Kielian M. Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression. Journal of Neuroimmunology. 130: 86-99. PMID 12225891 DOI: 10.1016/S0165-5728(02)00216-3 |
0.48 |
|
| 2002 |
Kielian T, van Rooijen N, Hickey WF. MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivo. Journal of Neuro-Oncology. 56: 1-12. PMID 11949821 DOI: 10.1023/A:1014495613455 |
0.369 |
|
| 2001 |
Kielian T, Cheung A, Hickey WF. Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infection and Immunity. 69: 6902-11. PMID 11598065 DOI: 10.1128/Iai.69.11.6902-6911.2001 |
0.377 |
|
| 2001 |
Kielian T, Barry B, Hickey WF. CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses. Journal of Immunology (Baltimore, Md. : 1950). 166: 4634-43. PMID 11254722 DOI: 10.4049/Jimmunol.166.7.4634 |
0.4 |
|
| 2000 |
Kielian T, Hickey WF. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development. The American Journal of Pathology. 157: 647-58. PMID 10934167 DOI: 10.1016/S0002-9440(10)64575-0 |
0.469 |
|
| 1995 |
Kielian TL, Blecha F. CD14 and other recognition molecules for lipopolysaccharide: a review. Immunopharmacology. 29: 187-205. PMID 7542643 DOI: 10.1016/0162-3109(95)00003-C |
0.358 |
|
| 1994 |
Shi JN, Kielian TL, Chengappa MM, Smith JE, Blecha F, Dritz SS, Goodband RD, Nelssen JL, Tokach MD. Influence of β-glucan on nonspecific immunity and growth performance in weanling pigs Kansas Agricultural Experiment Station Research Reports. 125-131. DOI: 10.4148/2378-5977.6419 |
0.308 |
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