Douglas L. Feinstein - Publications

Affiliations: 
University of Illinois at Chicago, Chicago, IL, United States 
Area:
Neuroimmunology
Website:
http://feinsteinlabs.rog

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Moutal A, Kalinin S, Kowal K, Marangoni N, Dupree J, Lin SX, Lis K, Lisi L, Hensley K, Khanna R, Feinstein DL. Neuronal Conditional Knockout of Collapsin Response Mediator Protein 2 Ameliorates Disease Severity in a Mouse Model of Multiple Sclerosis. Asn Neuro. 11: 1759091419892090. PMID 31795726 DOI: 10.1177/1759091419892090  0.576
2019 Kalinin S, Meares GP, Lin SX, Pietruczyk EA, Saher G, Spieth L, Nave KA, Boullerne AI, Lutz SE, Benveniste EN, Feinstein DL. Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. Glia. PMID 31664743 DOI: 10.1002/Glia.23742  0.407
2019 Lisi L, Pia Ciotti GM, Chiavari M, Pizzoferrato M, Mangiola A, Kalinin S, Feinstein DL, Navarra P. Phospho-mTOR expression in human glioblastoma microglia-macrophage cells. Neurochemistry International. 104485. PMID 31195027 DOI: 10.1016/J.Neuint.2019.104485  0.683
2019 Savchenko V, Kalinin S, Boullerne AI, Kowal K, Lin SX, Feinstein DL. Effects of the CRMP2 activator lanthionine ketimine ethyl ester on oligodendrocyte progenitor cells. Journal of Neuroimmunology. 334: 576977. PMID 31177034 DOI: 10.1016/J.Jneuroim.2019.576977  0.406
2019 Moutal A, White KA, Chefdeville A, Laufmann RN, Vitiello PF, Feinstein D, Weimer JM, Khanna R. Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions. Molecular Neurobiology. PMID 30915713 DOI: 10.1007/S12035-019-1568-4  0.317
2018 Lindeblad M, Lyubimov A, van Breemen R, Gierszal K, Weinberg G, Rubinstein I, Feinstein DL. The bile sequestrant cholestyramine increases survival in a rabbit model of brodifacoum poisoning. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29897553 DOI: 10.1093/Toxsci/Kfy147  0.301
2018 Kalinin S, González-Prieto M, Scheiblich H, Lisi L, Kusumo H, Heneka MT, Madrigal JLM, Pandey SC, Feinstein DL. Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. Journal of Neuroinflammation. 15: 141. PMID 29759078 DOI: 10.1186/S12974-018-1184-7  0.651
2018 Gutiérrez IL, González-Prieto M, García-Bueno B, Caso JR, Feinstein DL, Madrigal JLM. CCL2 Induces the Production of β2 Adrenergic Receptors and Modifies Astrocytic Responses to Noradrenaline. Molecular Neurobiology. PMID 29478130 DOI: 10.1007/S12035-018-0960-9  0.46
2017 Braun D, Feinstein DL. The locus coeruleus neuroprotective drug vindeburnol normalizes behavior in the 5xFAD transgenic mouse model of Alzheimer's disease. Brain Research. PMID 29274883 DOI: 10.1016/J.Brainres.2017.12.028  0.343
2017 Marangoni N, Kowal K, Deliu Z, Hensley K, Feinstein DL. Neuroprotective and neurotrophic effects of Lanthionine Ketimine Ester. Neuroscience Letters. 664: 28-33. PMID 29128626 DOI: 10.1016/J.Neulet.2017.11.018  0.371
2017 Kalinin S, Marangoni N, Kowal K, Dey A, Lis K, Brodsky S, van Breemen R, Hauck Z, Ripper R, Rubinstein I, Weinberg G, Feinstein DL. The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 159: 224-237. PMID 28903499 DOI: 10.1093/Toxsci/Kfx134  0.365
2017 Ware KM, Feinstein DL, Rubinstein I, Battula P, Otero J, Hebert L, Wang TF, Ivanova A, Chaudhary S, Hemminger J, Brodsky SV. The Severity of Intracranial Hemorrhages Measured by Free Hemoglobin in the Brain Depends on the Anticoagulant Class: Experimental Data. Stroke Research and Treatment. 2017: 6516401. PMID 28808596 DOI: 10.1155/2017/6516401  0.317
2017 Changyaleket B, Deliu Z, Chignalia AZ, Feinstein DL. Heparanase: Potential roles in multiple sclerosis. Journal of Neuroimmunology. 310: 72-81. PMID 28778449 DOI: 10.1016/J.Jneuroim.2017.07.001  0.329
2017 Braun DJ, Kalinin S, Feinstein DL. Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer's Disease. Asn Neuro. 9: 1759091417696161. PMID 28266222 DOI: 10.1177/1759091417696161  0.347
2017 Lisi L, Ciotti GM, Braun D, Kalinin S, Currò D, Dello Russo C, Coli A, Mangiola A, Anile C, Feinstein DL, Navarra P. Expression of iNOS, CD163 and ARG-1 taken as M1 and M2 markers of microglial polarization in human glioblastoma and the surrounding normal parenchyma. Neuroscience Letters. 645: 106-112. PMID 28259657 DOI: 10.1016/J.Neulet.2017.02.076  0.745
2016 Marangoni MN, Braun D, Situ A, Moyano AL, Kalinin S, Polak P, Givogri MI, Feinstein DL. Differential effects on glial activation by a direct versus an indirect thrombin inhibitor. Journal of Neuroimmunology. 297: 159-68. PMID 27397090 DOI: 10.1016/J.Jneuroim.2016.05.018  0.433
2016 Feinstein DL, Skoff RP. Glial cell biology in the Great Lakes region. Journal of Neuroinflammation. 13: 69. PMID 27029404 DOI: 10.1186/S12974-016-0534-6  0.335
2016 Feinstein DL, Kalinin S, Braun D. Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system. Journal of Neurochemistry. PMID 26968403 DOI: 10.1111/Jnc.13447  0.397
2015 Dupree JL, Polak PE, Hensley K, Pelligrino D, Feinstein DL. Lanthionine ketimine ester provides benefit in a mouse model of multiple sclerosis. Journal of Neurochemistry. 134: 302-14. PMID 25846048 DOI: 10.1111/Jnc.13114  0.346
2015 Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5  0.556
2015 Braun D, Feinstein D, Engelhard H. Abstract A14: Loss of LKB1 gene alone causes malignant transformation of astrocytes Brain. 75. DOI: 10.1158/1538-7445.Brain15-A14  0.363
2014 Braun D, Madrigal JL, Feinstein DL. Noradrenergic regulation of glial activation: molecular mechanisms and therapeutic implications. Current Neuropharmacology. 12: 342-52. PMID 25342942 DOI: 10.2174/1570159X12666140828220938  0.435
2014 Polak PE, Lin SX, Pelligrino D, Feinstein DL. The blood-brain barrier-permeable catechol-O-methyltransferase inhibitor dinitrocatechol suppresses experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 276: 135-41. PMID 25242632 DOI: 10.1016/J.Jneuroim.2014.09.004  0.33
2013 Ghods AJ, Glick R, Braun D, Feinstein D. Beneficial actions of the anti-inflammatory dimethyl fumarate in glioblastomas. Surgical Neurology International. 4: 160. PMID 24404403 DOI: 10.4103/2152-7806.123656  0.36
2013 Kalinin S, Polak PE, Lin SX, Braun D, Guizzetti M, Zhang X, Rubinstein I, Feinstein DL. Dimethyl fumarate regulates histone deacetylase expression in astrocytes. Journal of Neuroimmunology. 263: 13-9. PMID 23916696 DOI: 10.1016/J.Jneuroim.2013.07.007  0.427
2013 Kalinin S, Willard SL, Shively CA, Kaplan JR, Register TC, Jorgensen MJ, Polak PE, Rubinstein I, Feinstein DL. Development of amyloid burden in African Green monkeys. Neurobiology of Aging. 34: 2361-9. PMID 23601810 DOI: 10.1016/J.Neurobiolaging.2013.03.023  0.331
2013 Lisi L, McGuire S, Sharp A, Chiosis G, Navarra P, Feinstein DL, Dello Russo C. The novel HSP90 inhibitor, PU-H71, suppresses glial cell activation but weakly affects clinical signs of EAE. Journal of Neuroimmunology. 255: 1-7. PMID 23123171 DOI: 10.1016/J.Jneuroim.2012.10.008  0.77
2013 Dello Russo C, Lisi L, Feinstein DL, Navarra P. mTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis. Glia. 61: 301-11. PMID 23044764 DOI: 10.1002/Glia.22433  0.779
2012 Polak PE, Dull RO, Kalinin S, Sharp AJ, Ripper R, Weinberg G, Schwartz DE, Rubinstein I, Feinstein DL. Sevoflurane reduces clinical disease in a mouse model of multiple sclerosis. Journal of Neuroinflammation. 9: 272. PMID 23253693 DOI: 10.1186/1742-2094-9-272  0.395
2012 Polak PE, Kalinin S, Braun D, Sharp A, Lin SX, Feinstein DL. The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus. Journal of Neurochemistry. 121: 206-16. PMID 22288774 DOI: 10.1111/J.1471-4159.2012.07673.X  0.426
2012 Lisi L, Navarra P, Cirocchi R, Sharp A, Stigliano E, Feinstein DL, Dello Russo C. Rapamycin reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 243: 43-51. PMID 22264993 DOI: 10.1016/J.Jneuroim.2011.12.018  0.758
2012 Xin J, Feinstein DL, Hejna MJ, Lorens SA, McGuire SO. Beneficial effects of blueberries in experimental autoimmune encephalomyelitis. Journal of Agricultural and Food Chemistry. 60: 5743-8. PMID 22243431 DOI: 10.1021/Jf203611T  0.304
2012 Kalinin S, Polak PE, Lin SX, Sakharkar AJ, Pandey SC, Feinstein DL. The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease. Neurobiology of Aging. 33: 1651-63. PMID 21705113 DOI: 10.1016/J.Neurobiolaging.2011.04.012  0.373
2011 Lin SX, Lisi L, Dello Russo C, Polak PE, Sharp A, Weinberg G, Kalinin S, Feinstein DL. The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1. Asn Neuro. 3. PMID 21382015 DOI: 10.1042/An20100033  0.767
2011 Polak PE, Kalinin S, Feinstein DL. Locus coeruleus damage and noradrenaline reductions in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. 134: 665-77. PMID 21297130 DOI: 10.1093/Brain/Awq362  0.399
2011 Pifarre P, Prado J, Baltrons MA, Giralt M, Gabarro P, Feinstein DL, Hidalgo J, Garcia A. Sildenafil (Viagra) ameliorates clinical symptoms and neuropathology in a mouse model of multiple sclerosis. Acta Neuropathologica. 121: 499-508. PMID 21234581 DOI: 10.1007/S00401-010-0795-6  0.411
2011 Lisi L, Navarra P, Feinstein DL, Dello Russo C. The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes. Journal of Neuroinflammation. 8: 1. PMID 21208419 DOI: 10.1186/1742-2094-8-1  0.797
2010 Madrigal JL, Garcia-Bueno B, Hinojosa AE, Polak P, Feinstein DL, Leza JC. Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. Journal of Neurochemistry. 113: 543-51. PMID 20132473 DOI: 10.1111/J.1471-4159.2010.06623.X  0.386
2010 Simonini MV, Polak PE, Sharp A, McGuire S, Galea E, Feinstein DL. Increasing CNS noradrenaline reduces EAE severity. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 252-9. PMID 19957206 DOI: 10.1007/S11481-009-9182-2  0.399
2010 Akar C, Kalinin S, Gavrilyuk V, Spagnolo A, Weinberg G, Feinstein DL. Receptor-independent metabolic effects of thiazolidinediones in astrocytes Open Cancer Immunology Journal. 3: 36-40. DOI: 10.2174/1876401001003010036  0.676
2010 Ksendzovsky A, Glick RP, Polak P, Simonini MV, Sharp AJ, Newman T, Cohen EP, Feinstein DL. Mechanisms of cytokine-induced glioma immunosuppression Open Cancer Immunology Journal. 3: 30-35. DOI: 10.2174/1876401001003010030  0.328
2009 Kalinin S, Richardson JC, Feinstein DL. A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease. Current Alzheimer Research. 6: 431-7. PMID 19874267 DOI: 10.2174/156720509789207949  0.434
2009 Kaiser CC, Shukla DK, Stebbins GT, Skias DD, Jeffery DR, Stefoski D, Katsamakis G, Feinstein DL. A pilot test of pioglitazone as an add-on in patients with relapsing remitting multiple sclerosis. Journal of Neuroimmunology. 211: 124-30. PMID 19446890 DOI: 10.1016/J.Jneuroim.2009.04.011  0.317
2009 Ksendzovsky A, Feinstein D, Zengou R, Sharp A, Polak P, Lichtor T, Glick RP. Investigation of immunosuppressive mechanisms in a mouse glioma model Journal of Neuro-Oncology. 93: 107-114. PMID 19430886 DOI: 10.1007/S11060-009-9884-6  0.372
2009 Akar CA, Feinstein DL. Modulation of inducible nitric oxide synthase expression by sumoylation. Journal of Neuroinflammation. 6: 12. PMID 19323834 DOI: 10.1186/1742-2094-6-12  0.426
2009 Madrigal JL, Leza JC, Polak P, Kalinin S, Feinstein DL. Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 263-7. PMID 19129402 DOI: 10.1523/Jneurosci.4926-08.2009  0.416
2008 Sharp AJ, Polak PE, Simonini V, Lin SX, Richardson JC, Bongarzone ER, Feinstein DL. P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 5: 33. PMID 18691411 DOI: 10.1186/1742-2094-5-33  0.379
2008 Lichtor T, Spagnolo A, Glick RP, Feinstein DL. PPAR-gamma Thiazolidinedione Agonists and Immunotherapy in the Treatment of Brain Tumors. Ppar Research. 2008: 547470. PMID 18509487 DOI: 10.1155/2008/547470  0.374
2008 Feinstein DL, Brosnan CF, Whitacre CC, Landreth GE, Gavrilyuk V, Heneka MT. PPAR-agonists prevent experimental autoimmune encephalomyelitis Journal of Neurochemistry. 81: 36-36. DOI: 10.1046/J.1471-4159.81.S1.81.X  0.733
2008 Dello Russo C, Gavrilyuk V, Feinstein DL. Inter-relationship of cytokine production and NOS2 expression in microglia Journal of Neurochemistry. 81: 52-53. DOI: 10.1046/J.1471-4159.81.S1.17_5.X  0.633
2007 Madrigal JL, Kalinin S, Richardson JC, Feinstein DL. Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta. Journal of Neurochemistry. 103: 2092-101. PMID 17854349 DOI: 10.1111/J.1471-4159.2007.04888.X  0.396
2007 Spagnolo A, Glick RP, Lin H, Cohen EP, Feinstein DL, Lichtor T. Prolonged survival of mice with established intracerebral glioma receiving combined treatment with peroxisome proliferator-activated receptor-gamma thiazolidinedione agonists and interleukin-2-secreting syngeneic/allogeneic fibroblasts. Journal of Neurosurgery. 106: 299-305. PMID 17410715 DOI: 10.3171/Jns.2007.106.2.299  0.376
2007 Tureyen K, Kapadia R, Bowen KK, Satriotomo I, Liang J, Feinstein DL, Vemuganti R. Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. Journal of Neurochemistry. 101: 41-56. PMID 17394460 DOI: 10.1111/J.1471-4159.2006.04376.X  0.423
2007 Spagnolo A, Grant EN, Glick R, Lichtor T, Feinstein DL. Differential effects of PPARgamma agonists on the metabolic properties of gliomas and astrocytes. Neuroscience Letters. 417: 72-7. PMID 17324516 DOI: 10.1016/J.Neulet.2007.02.036  0.369
2007 Boris M, Kaiser CC, Goldblatt A, Elice MW, Edelson SM, Adams JB, Feinstein DL. Effect of pioglitazone treatment on behavioral symptoms in autistic children. Journal of Neuroinflammation. 4: 3. PMID 17207275 DOI: 10.1186/1742-2094-4-3  0.321
2007 Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiology of Aging. 28: 1206-14. PMID 16837104 DOI: 10.1016/J.Neurobiolaging.2006.06.003  0.694
2006 Kalinin S, Feinstein DL, Xu HL, Huesa G, Pelligrino DA, Galea E. Degeneration of noradrenergic fibres from the locus coeruleus causes tight-junction disorganisation in the rat brain. The European Journal of Neuroscience. 24: 3393-400. PMID 17229089 DOI: 10.1111/J.1460-9568.2006.05223.X  0.392
2006 Phulwani NK, Feinstein DL, Gavrilyuk V, Akar C, Kielian T. 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. Journal of Neurochemistry. 99: 1389-1402. PMID 17074064 DOI: 10.1111/J.1471-4159.2006.04183.X  0.674
2006 Dello Russo C, Polak PE, Mercado PR, Spagnolo A, Sharp A, Murphy P, Kamal A, Burrows FJ, Fritz LC, Feinstein DL. The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis. Journal of Neurochemistry. 99: 1351-62. PMID 17064348 DOI: 10.1111/J.1471-4159.2006.04221.X  0.691
2006 Grommes C, Landreth GE, Sastre M, Beck M, Feinstein DL, Jacobs AH, Schlegel U, Heneka MT. Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment. Molecular Pharmacology. 70: 1524-33. PMID 16887936 DOI: 10.1124/Mol.106.022194  0.57
2006 Galea E, Feinstein DL, Lacombe P. Pioglitazone does not increase cerebral glucose utilisation in a murine model of Alzheimer's disease and decreases it in wild-type mice. Diabetologia. 49: 2153-61. PMID 16830140 DOI: 10.1007/S00125-006-0326-0  0.349
2006 Madrigal JL, Dello Russo C, Gavrilyuk V, Feinstein DL. Effects of noradrenaline on neuronal NOS2 expression and viability. Antioxidants & Redox Signaling. 8: 885-92. PMID 16771678 DOI: 10.1089/Ars.2006.8.885  0.742
2006 Kalinin S, Polak PE, Madrigal JL, Gavrilyuk V, Sharp A, Chauhan N, Marien M, Colpaert F, Feinstein DL. Beta-amyloid-dependent expression of NOS2 in neurons: prevention by an alpha2-adrenergic antagonist. Antioxidants & Redox Signaling. 8: 873-83. PMID 16771677 DOI: 10.1089/Ars.2006.8.873  0.647
2006 Wu C, Tian D, Feng Y, Polak P, Wei J, Sharp A, Stankoff B, Lubetzki C, Zalc B, Mufson EJ, Gould RM, Feinstein DL, Wang Y. A novel fluorescent probe that is brain permeable and selectively binds to myelin. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 997-1004. PMID 16709728 DOI: 10.1369/Jhc.5A6901.2006  0.308
2006 Heneka MT, Leimer U, Van Leuven F, Sastre M, Dumitrescu-Ozimek L, Feinstein DL. P3-283: Differential regulation of microglial cytokine production, phagocytosis and migration by norepinephrine: How locus ceruleus degeneration affects Alzheimer disease Alzheimer's & Dementia. 2: S458-S459. DOI: 10.1016/J.Jalz.2006.05.1552  0.519
2005 Polak PE, Kalinin S, Dello Russo C, Gavrilyuk V, Sharp A, Peters JM, Richardson J, Willson TM, Weinberg G, Feinstein DL. Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 168: 65-75. PMID 16098614 DOI: 10.1016/J.Jneuroim.2005.07.006  0.77
2005 Madrigal JL, Feinstein DL, Dello Russo C. Norepinephrine protects cortical neurons against microglial-induced cell death. Journal of Neuroscience Research. 81: 390-6. PMID 15948176 DOI: 10.1002/Jnr.20481  0.681
2005 Feinstein DL, Spagnolo A, Akar C, Weinberg G, Murphy P, Gavrilyuk V, Dello Russo C. Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key? Biochemical Pharmacology. 70: 177-88. PMID 15925327 DOI: 10.1016/J.Bcp.2005.03.033  0.726
2005 Gavrilyuk V, Kalinin S, Hilbush BS, Middlecamp A, McGuire S, Pelligrino D, Weinberg G, Feinstein DL. Identification of complement 5a-like receptor (C5L2) from astrocytes: characterization of anti-inflammatory properties. Journal of Neurochemistry. 92: 1140-9. PMID 15715664 DOI: 10.1111/J.1471-4159.2004.02942.X  0.683
2005 Chauhan NB, Siegel GJ, Feinstein DL. Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576. Neuropharmacology. 48: 93-104. PMID 15617731 DOI: 10.1016/J.Neuropharm.2004.09.014  0.352
2004 Chauhan NB, Siegel GJ, Feinstein DL. Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. Neurochemical Research. 29: 1897-911. PMID 15532546 DOI: 10.1023/B:Nere.0000042217.90204.8D  0.385
2004 Lacombe P, Mathews PM, Schmidt SD, Breidert T, Heneka MT, Landreth GE, Feinstein DL, Galea E. Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. Journal of Neuroinflammation. 1: 11. PMID 15285804 DOI: 10.1186/1742-2094-1-11  0.589
2004 Pershadsingh HA, Heneka MT, Saini R, Amin NM, Broeske DJ, Feinstein DL. Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. Journal of Neuroinflammation. 1: 3. PMID 15285799 DOI: 10.1186/1742-2094-1-3  0.52
2004 Dello Russo C, Boullerne AI, Gavrilyuk V, Feinstein DL. Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1beta production. Journal of Neuroinflammation. 1: 9. PMID 15285793 DOI: 10.1186/1742-2094-1-9  0.763
2004 Xu HL, Koenig HM, Ye S, Feinstein DL, Pelligrino DA. Influence of the glia limitans on pial arteriolar relaxation in the rat. American Journal of Physiology. Heart and Circulatory Physiology. 287: H331-9. PMID 14962837 DOI: 10.1152/Ajpheart.00831.2003  0.318
2004 Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. Journal of Leukocyte Biology. 75: 478-85. PMID 14657213 DOI: 10.1189/Jlb.0803402  0.578
2004 Feinstein DL, Heneka MT, Kalinin S, Chauhan N, Gavrilyuk V. O3-04-04 Cortical noradrenergic depletion accelerates pathology in TGAPP mice Neurobiology of Aging. 25: S60. DOI: 10.1016/S0197-4580(04)80201-X  0.633
2004 Feinstein DL. Contrasting the neuroprotective and gliotoxic effects of PPARγ agonists Drug Discovery Today: Therapeutic Strategies. 1: 29-34. DOI: 10.1016/J.Ddstr.2004.08.011  0.438
2003 Galea E, Heneka MT, Dello Russo C, Feinstein DL. Intrinsic regulation of brain inflammatory responses. Cellular and Molecular Neurobiology. 23: 625-35. PMID 14514020 DOI: 10.1023/A:1025084415833  0.742
2003 Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. Journal of Neurochemistry. 86: 907-16. PMID 12887689 DOI: 10.1046/J.1471-4159.2003.01909.X  0.748
2003 Feinstein DL. Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease. Diabetes Technology & Therapeutics. 5: 67-73. PMID 12725709 DOI: 10.1089/152091503763816481  0.434
2003 Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. Journal of Neurochemistry. 85: 387-98. PMID 12675915 DOI: 10.1046/J.1471-4159.2003.01694.X  0.742
2003 Duvanel CB, Honegger P, Pershadsingh H, Feinstein D, Matthieu JM. Inhibition of glial cell proinflammatory activities by peroxisome proliferator-activated receptor gamma agonist confers partial protection during antimyelin oligodendrocyte glycoprotein demyelination in vitro Journal of Neuroscience Research. 71: 246-255. PMID 12503087 DOI: 10.1002/Jnr.10471  0.448
2003 Dello Russo C, Gavrilyuk V, Weinberg G, Almeida A, Bolanos JP, Palmer J, Pelligrino D, Galea E, Feinstein DL. Peroxisome proliferator-activated receptor gamma thiazolidinedione agonists increase glucose metabolism in astrocytes. The Journal of Biological Chemistry. 278: 5828-36. PMID 12486128 DOI: 10.1074/Jbc.M208132200  0.742
2002 Feinstein DL, Heneka MT, Gavrilyuk V, Dello Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochemistry International. 41: 357-65. PMID 12176079 DOI: 10.1016/S0197-0186(02)00049-9  0.795
2002 Galea E, Santizo R, Feinstein DL, Adamsom P, Greenwood J, Koenig HM, Pelligrino DA. Estrogen inhibits NF kappa B-dependent inflammation in brain endothelium without interfering with I kappa B degradation. Neuroreport. 13: 1469-72. PMID 12167775 DOI: 10.1097/00001756-200208070-00024  0.39
2002 Zekki H, Feinstein DL, Rivest S. The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS. Brain Pathology (Zurich, Switzerland). 12: 308-19. PMID 12146799 DOI: 10.1111/J.1750-3639.2002.Tb00445.X  0.394
2002 Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G, Heneka MT. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Annals of Neurology. 51: 694-702. PMID 12112074 DOI: 10.1002/Ana.10206  0.735
2002 Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. Journal of Neurochemistry. 81: 1052-60. PMID 12065618 DOI: 10.1046/J.1471-4159.2002.00899.X  0.559
2002 Gavrilyuk V, Dello Russo C, Heneka MT, Pelligrino D, Weinberg G, Feinstein DL. Norepinephrine increases I kappa B alpha expression in astrocytes. The Journal of Biological Chemistry. 277: 29662-8. PMID 12050158 DOI: 10.1074/Jbc.M203256200  0.776
2002 Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2434-42. PMID 11923407 DOI: 10.1046/J.1471-4159.81.S1.20_10.X  0.601
2002 Murphy P, Sharp A, Shin J, Gavrilyuk V, Dello Russo C, Weinberg G, Sharp FR, Lu A, Heneka MT, Feinstein DL. Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 67: 461-70. PMID 11835313 DOI: 10.1002/Jnr.10139  0.815
2002 Xu HL, Feinstein DL, Santizo RA, Koenig HM, Pelligrino DA. Agonist-specific differences in mechanisms mediating eNOS-dependent pial arteriolar dilation in rats. American Journal of Physiology. Heart and Circulatory Physiology. 282: H237-43. PMID 11748068 DOI: 10.1152/Ajpheart.2002.282.1.H237  0.372
2002 Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic Depletion Potentiates β-Amyloid-Induced Cortical Inflammation: Implications for Alzheimer's Disease The Journal of Neuroscience. 22: 2434-2442. DOI: 10.1523/Jneurosci.22-07-02434.2002  0.586
2001 Heneka MT, Wiesinger H, Dumitrescu-Ozimek L, Riederer P, Feinstein DL, Klockgether T. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 906-16. PMID 11556547 DOI: 10.1093/Jnen/60.9.906  0.578
2001 Gavrilyuk V, Horvath P, Weinberg G, Feinstein DL. A 27-bp region of the inducible nitric oxide synthase promoter regulates expression in glial cells. Journal of Neurochemistry. 78: 129-40. PMID 11432980 DOI: 10.1046/J.1471-4159.2001.00375.X  0.653
2001 Heneka MT, Sharp A, Murphy P, Lyons JA, Dumitrescu L, Feinstein DL. The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice. Journal of Neurochemistry. 77: 568-79. PMID 11299319 DOI: 10.1046/J.1471-4159.2001.00260.X  0.613
2001 Feinstein DL, Murphy P, Sharp A, Galea E, Gavrilyuk V, Weinberg G. Local anesthetics potentiate nitric oxide synthase type 2 expression in rat glial cells. Journal of Neurosurgical Anesthesiology. 13: 99-105. PMID 11294465 DOI: 10.1097/00008506-200104000-00006  0.652
2001 Heneka MT, Feinstein DL. Expression and function of inducible nitric oxide synthase in neurons. Journal of Neuroimmunology. 114: 8-18. PMID 11240010 DOI: 10.1016/S0165-5728(01)00246-6  0.578
2001 Heneka MT, Landreth GE, Feinstein DL. Role for peroxisome proliferator-activated receptor-gamma in Alzheimer's disease. Annals of Neurology. 49: 276. PMID 11220752 DOI: 10.1002/1531-8249(20010201)49:2<276::Aid-Ana53>3.0.Co;2-5  0.519
2000 Gould RM, Freund CM, Palmer F, Feinstein DL. Messenger RNAs located in myelin sheath assembly sites. Journal of Neurochemistry. 75: 1834-44. PMID 11032872 DOI: 10.1046/J.1471-4159.2000.0751834.X  0.302
2000 Heneka MT, Klockgether T, Feinstein DL. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6862-7. PMID 10995830  0.589
2000 Stasiolek M, Gavrilyuk V, Sharp A, Horvath P, Selmaj K, Feinstein DL. Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells. The role of Ikappa B-beta. The Journal of Biological Chemistry. 275: 24847-56. PMID 10827092 DOI: 10.1074/Jbc.M910284199  0.662
2000 Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL. The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 800-11. PMID 10826530 DOI: 10.1097/00004647-200005000-00006  0.746
2000 Pelligrino DA, Ye S, Tan F, Santizo RA, Feinstein DL, Wang Q. Nitric-oxide-dependent pial arteriolar dilation in the female rat: effects of chronic estrogen depletion and repletion. Biochemical and Biophysical Research Communications. 269: 165-71. PMID 10694495 DOI: 10.1006/Bbrc.2000.2206  0.324
2000 Heneka MT, Klockgether T, Feinstein DL. Peroxisome Proliferator-Activated Receptor-γ Ligands Reduce Neuronal Inducible Nitric Oxide Synthase Expression and Cell DeathIn Vivo The Journal of Neuroscience. 20: 6862-6867. DOI: 10.1523/Jneurosci.20-18-06862.2000  0.638
1999 Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wüllner U, Klockgether T. Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. Journal of Neuroimmunology. 100: 156-68. PMID 10695726 DOI: 10.1016/S0165-5728(99)00192-7  0.622
1999 Galea E, Feinstein DL. Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 2125-37. PMID 10593859 DOI: 10.1096/Fasebj.13.15.2125  0.442
1999 Regunathan S, Feinstein DL, Reis DJ. Anti-proliferative and anti-inflammatory actions of imidazoline agents. Are imidazoline receptors involved? Annals of the New York Academy of Sciences. 881: 410-9. PMID 10415945 DOI: 10.1111/J.1749-6632.1999.Tb09389.X  0.593
1999 Feinstein DL, Reis DJ, Regunathan S. Inhibition of astroglial nitric oxide synthase type 2 expression by idazoxan. Molecular Pharmacology. 55: 304-8. PMID 9927622 DOI: 10.1124/Mol.55.2.304  0.611
1998 Galea E, Glickstein SB, Feinstein DL, Golanov EV, Reis DJ. Stimulation of cerebellar fastigial nucleus inhibits interleukin-1β-induced cerebrovascular inflammation. American Journal of Physiology. Heart and Circulatory Physiology. 275: H2053-H2063. PMID 29586765 DOI: 10.1152/ajpheart.1998.275.6.H2053  0.461
1998 Galea E, Golanov EV, Feinstein DL, Kobylarz KA, Glickstein SB, Reis DJ. Cerebellar stimulation reduces inducible nitric oxide synthase expression and protects brain from ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 274: H2035-H2045. PMID 29585932 DOI: 10.1152/ajpheart.1998.274.6.H2035  0.499
1998 Galea E, Glickstein SB, Feinstein DL, Golanov EV, Reis DJ. Stimulation of cerebellar fastigial nucleus inhibits interleukin-1beta-induced cerebrovascular inflammation. The American Journal of Physiology. 275: H2053-63. PMID 9843804 DOI: 10.1152/Ajpheart.1998.275.6.H2053  0.548
1998 Galea E, Golanov EV, Feinstein DL, Kobylarz KA, Glickstein SB, Reis DJ. Cerebellar stimulation reduces inducible nitric oxide synthase expression and protects brain from ischemia. The American Journal of Physiology. 274: H2035-45. PMID 9841530 DOI: 10.1152/Ajpheart.1998.274.6.H2035  0.558
1998 Feinstein DL. Potentiation of astroglial nitric oxide synthase type-2 expression by lithium chloride. Journal of Neurochemistry. 71: 883-6. PMID 9681482 DOI: 10.1046/J.1471-4159.1998.71020883.X  0.453
1998 Feinstein DL. Suppression of astroglial nitric oxide synthase expression by norepinephrine results from decreased NOS-2 promoter activity. Journal of Neurochemistry. 70: 1484-96. PMID 9523565 DOI: 10.1046/J.1471-4159.1998.70041484.X  0.445
1998 Sastre M, Galea E, Feinstein D, Reis DJ, Regunathan S. Metabolism of agmatine in macrophages: modulation by lipopolysaccharide and inhibitory cytokines. The Biochemical Journal. 330: 1405-9. PMID 9494113 DOI: 10.1042/Bj3301405  0.531
1998 Galea E, Glickstein SB, Feinstein DL, Golanov EV, Reis DJ. Stimulation of cerebellar fastigial nucleus inhibits interleukin-1β-induced cerebrovascular inflammation American Journal of Physiology - Heart and Circulatory Physiology. 44: H2053-H2063.  0.411
1997 Feinstein DL, Galea E, Reis DJ. Suppression of glial nitric oxide synthase induction by heat shock: effects on proteolytic degradation of IkappaB-alpha. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 1: 167-76. PMID 9701055 DOI: 10.1006/Niox.1997.0117  0.553
1997 Reis DJ, Golanov EV, Galea E, Feinstein DL. Central neurogenic neuroprotection: central neural systems that protect the brain from hypoxia and ischemia. Annals of the New York Academy of Sciences. 835: 168-86. PMID 9616772 DOI: 10.1111/J.1749-6632.1997.Tb48628.X  0.507
1997 Feinstein DL, Rozelman E. Norepinephrine suppresses L-arginine uptake in rat glial cells. Neuroscience Letters. 223: 37-40. PMID 9058417 DOI: 10.1016/S0304-3940(97)13402-4  0.392
1997 Reis DJ, Feinstein D, Galea E, Golanov EV. Central neurogenic neuroprotection: Protection of brain from focal ischemia by cerebellar stimulation Fundamental and Clinical Pharmacology. 11: 39s-43s. DOI: 10.1111/J.1472-8206.1997.Tb00873.X  0.513
1996 Weng G, Feinstein D, Reis D, Wahlestedt C. Neuropeptide Y receptor gene regulation in mouse adrenocortical Y-1 cells. Regulatory Peptides. 63: 53-6. PMID 8795089 DOI: 10.1016/0167-0115(96)00030-4  0.538
1996 Feinstein DL, Galea E, Aquino DA, Li GC, Xu H, Reis DJ. Heat shock protein 70 suppresses astroglial-inducible nitric-oxide synthase expression by decreasing NFkappaB activation. The Journal of Biological Chemistry. 271: 17724-32. PMID 8663604 DOI: 10.1074/Jbc.271.30.17724  0.595
1996 Galea E, Regunathan S, Eliopoulos V, Feinstein DL, Reis DJ. Inhibition of mammalian nitric oxide synthases by agmatine, an endogenous polyamine formed by decarboxylation of arginine. The Biochemical Journal. 316: 247-9. PMID 8645212 DOI: 10.1042/Bj3160247  0.5
1996 Galea E, Reis DJ, Fox ES, Xu H, Feinstein DL. CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells. Journal of Neuroimmunology. 64: 19-28. PMID 8598386 DOI: 10.1016/0165-5728(95)00143-3  0.529
1995 Galea E, Reddi J, Feinstein DL. Differential suppression of glial nitric oxide synthase induction by structurally related tyrosine kinase inhibitors. Neuroscience Letters. 200: 195-8. PMID 9064610 DOI: 10.1016/0304-3940(94)12119-B  0.402
1995 Regunathan S, Feinstein DL, Raasch W, Reis DJ. Agmatine (decarboxylated arginine) is synthesized and stored in astrocytes. Neuroreport. 6: 1897-900. PMID 8547593 DOI: 10.1097/00001756-199510020-00018  0.569
1995 Galea E, Reis DJ, Xu H, Feinstein DL. Transient expression of calcium-independent nitric oxide synthase in blood vessels during brain development. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1632-7. PMID 8529843 DOI: 10.1096/Fasebj.9.15.8529843  0.52
1995 Galea E, Dupouey P, Feinstein DL. Glial fibrillary acidic protein mRNA isotypes: expression in vitro and in vivo. Journal of Neuroscience Research. 41: 452-61. PMID 7473876 DOI: 10.1002/Jnr.490410404  0.373
1994 Reis DJ, Regunathan S, Golanov EV, Feinstein DL. Protection of focal ischemic infarction by rilmenidine in the animal: evidence that interactions with central imidazoline receptors may be neuroprotective. The American Journal of Cardiology. 74: 25A-30A. PMID 7998581 DOI: 10.1016/0002-9149(94)90038-8  0.524
1994 Feinstein DL, Galea E, Reis DJ. Suppression of glial iNOS expression by tyrosine kinase inhibitors. Annals of the New York Academy of Sciences. 738: 325-8. PMID 7530420 DOI: 10.1111/J.1749-6632.1994.Tb21818.X  0.49
1994 Galea E, Reis DJ, Feinstein DL. Cloning and expression of inducible nitric oxide synthase from rat astrocytes. Journal of Neuroscience Research. 37: 406-14. PMID 7513765 DOI: 10.1002/Jnr.490370313  0.546
1994 Feinstein DL, Galea E, Cermak J, Chugh P, Lyandvert L, Reis DJ. Nitric oxide synthase expression in glial cells: suppression by tyrosine kinase inhibitors. Journal of Neurochemistry. 62: 811-4. PMID 7507517 DOI: 10.1046/J.1471-4159.1994.62020811.X  0.563
1994 Feinstein DL, Galea E, Roberts S, Berquist H, Wang H, Reis DJ. Induction of nitric oxide synthase in rat C6 glioma cells. Journal of Neurochemistry. 62: 315-21. PMID 7505314 DOI: 10.1046/J.1471-4159.1994.62010315.X  0.553
1993 Regunathan S, Feinstein DL, Reis DJ. Expression of non-adrenergic imidazoline sites in rat cerebral cortical astrocytes. Journal of Neuroscience Research. 34: 681-8. PMID 8315666 DOI: 10.1002/Jnr.490340611  0.498
1993 Murphy S, Simmons ML, Agullo L, Garcia A, Feinstein DL, Galea E, Reis DJ, Minc-Golomb D, Schwartz JP. Synthesis of nitric oxide in CNS glial cells. Trends in Neurosciences. 16: 323-8. PMID 7691008 DOI: 10.1016/0166-2236(93)90109-Y  0.557
1993 Feinstein DL, Galea E, Reis DJ. Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. Journal of Neurochemistry. 60: 1945-8. PMID 7682604 DOI: 10.1111/J.1471-4159.1993.Tb13425.X  0.569
1992 Reis DJ, Regunathan S, Wang H, Feinstein DL, Meeley MP. Imidazoline receptors in the nervous system. Fundamental & Clinical Pharmacology. 6: 23S-29S. PMID 1324211 DOI: 10.1111/J.1472-8206.1992.Tb00138.X  0.45
1992 Galea E, Feinstein DL, Reis DJ. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proceedings of the National Academy of Sciences of the United States of America. 89: 10945-9. PMID 1279698 DOI: 10.1073/Pnas.89.22.10945  0.562
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