Feng-Chun Yang - Publications

Affiliations: 
Anatomy & Cell Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cell Biology, Biomechanics Biophysics, Molecular Biology, Evolution and Development Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Armstrong AE, Rhodes SD, Smith A, Chen S, Bessler W, Ferguson MJ, Jiang L, Li X, Yuan J, Yang X, Yang FC, Robertson KA, Ingram DA, Blakeley JO, Clapp DW. Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1. Pediatric Blood & Cancer. e28372. PMID 32459399 DOI: 10.1002/pbc.28372  0.72
2017 Zhou Y, He Y, Xing W, Zhang P, Shi H, Chen S, Shi J, Bai J, Rhodes SD, Zhang F, Yuan J, Yang X, Zhu X, Li Y, Hanenberg H, ... ... Yang FC, et al. Abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia. Haematologica. PMID 28341737 DOI: 10.3324/Haematol.2016.158717  0.72
2016 Shi H, Yamamoto S, Sheng M, Bai J, Zhang P, Chen R, Chen S, Shi L, Abdel-Wahab O, Xu M, Zhou Y, Yang FC. ASXL1 plays an important role in erythropoiesis. Scientific Reports. 6: 28789. PMID 27352931 DOI: 10.1038/srep28789  0.72
2016 Zhang P, Xing C, Rhodes SD, He Y, Deng K, Li Z, He F, Zhu C, Nguyen L, Zhou Y, Chen S, Mohammad KS, Guise TA, Abdel-Wahab O, Xu M, ... ... Yang FC, et al. Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice. Stem Cell Reports. PMID 27237378 DOI: 10.1016/J.Stemcr.2016.04.013  0.72
2016 Rhodes SD, Yang FC. Aberrant Myeloid Differentiation Contributes to the Development of Osteoporosis in Neurofibromatosis Type 1. Current Osteoporosis Reports. 14: 10-5. PMID 26932441 DOI: 10.1007/s11914-016-0298-z  0.72
2015 Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, ... Yang FC, et al. Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice. Cell Reports. PMID 26586431 DOI: 10.1182/Blood.V126.23.3650.3650  0.72
2015 Ferguson MJ, Rhodes SD, Jiang L, Li X, Yuan J, Yang X, Zhang S, Vakili ST, Territo P, Hutchins G, Yang FC, Ingram DA, Clapp DW, Chen S. Preclinical evidence for the use of sunitinib malate in the treatment of plexiform neurofibromas. Pediatric Blood & Cancer. PMID 26375012 DOI: 10.1002/Pbc.25763  0.72
2015 Childress P, Stayrook KR, Alvarez MB, Wang Z, Shao Y, Hernandez-Buquer S, Mack JK, Grese ZR, He Y, Horan D, Pavalko FM, Warden SJ, Robling AG, Yang FC, Allen MR, et al. Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis. Molecular Endocrinology (Baltimore, Md.). 29: 1269-85. PMID 26244796 DOI: 10.1210/Me.2014-1406  0.72
2015 Zhou Y, He Y, Sharma R, Xing W, Estwick SA, Wu X, Rhodes SD, Xu M, Yang FC. Hyperactive RAS/PI3-K/MAPK Signaling Cascade in Migration and Adhesion of Nf1 Haploinsufficient Mesenchymal Stem/Progenitor Cells. International Journal of Molecular Sciences. 16: 12345-59. PMID 26039236 DOI: 10.3390/Ijms160612345  0.72
2015 Rhodes SD, Yang H, Dong R, Menon K, He Y, Li Z, Chen S, Staser KW, Jiang L, Wu X, Yang X, Peng X, Mohammad KS, Guise TA, Xu M, ... Yang FC, et al. Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25917016 DOI: 10.1002/Jbmr.2538  0.72
2015 Rhodes SD, Zhang W, Yang D, Yang H, Chen S, Wu X, Li X, Yang X, Mohammad KS, Guise TA, Bergner AL, Stevenson DA, Yang FC. Dystrophic spinal deformities in a neurofibromatosis type 1 murine model. Plos One. 10: e0119093. PMID 25786243 DOI: 10.1371/Journal.Pone.0119093  0.72
2015 Gehlhausen JR, Park SJ, Hickox AE, Shew M, Staser K, Rhodes SD, Menon K, Lajiness JD, Mwanthi M, Yang X, Yuan J, Territo P, Hutchins G, Nalepa G, Yang FC, et al. A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation. Human Molecular Genetics. 24: 1-8. PMID 25113746 DOI: 10.1093/Hmg/Ddu414  0.72
2014 Li Y, Xing W, He YZ, Chen S, Rhodes SD, Yuan J, Zhou Y, Shi J, Bai J, Zhang FK, Yuan WP, Cheng T, Xu MJ, Yang FC. Interleukin 8/KC enhances G-CSF induced hematopoietic stem/progenitor cell mobilization in Fancg deficient mice. Stem Cell Investigation. 1: 19. PMID 27358865 DOI: 10.3978/J.Issn.2306-9759.2014.10.02  0.72
2014 Sheng MY, Shi H, Xing W, Wang WJ, Si XH, Bai J, Yuan WP, Zhou Y, Yang FC. [Anti-mouse CD122 antibody promotes the hematopoietic repopulating capacity of cord blood CD34⁺ cells in NOD/SCID mice]. Zhongguo Shi Yan Xue Ye Xue Za Zhi / Zhongguo Bing Li Sheng Li Xue Hui = Journal of Experimental Hematology / Chinese Association of Pathophysiology. 22: 1673-7. PMID 25543495 DOI: 10.7534/j.issn.1009-2137.2014.06.032  0.72
2014 Sheng MY, Zhou Y, Xu MJ, Yang FC. [Role of ASXL1 mutation in myeloid malignancies]. Zhongguo Shi Yan Xue Ye Xue Za Zhi / Zhongguo Bing Li Sheng Li Xue Hui = Journal of Experimental Hematology / Chinese Association of Pathophysiology. 22: 1183-7. PMID 25130853 DOI: 10.7534/j.issn.1009-2137.2014.04.057  0.72
2014 Chang L, Yuan W, Zeng H, Zhou Q, Wei W, Zhou J, Li M, Wang X, Xu M, Yang F, Yang Y, Cheng T, Zhu X. Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients. Bmc Medical Genomics. 7: 24. PMID 24885126 DOI: 10.1186/1755-8794-7-24  0.72
2014 Wang J, Li Z, He Y, Pan F, Chen S, Rhodes S, Nguyen L, Yuan J, Jiang L, Yang X, Weeks O, Liu Z, Zhou J, Ni H, Cai CL, ... ... Yang FC, et al. Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice. Blood. 123: 541-53. PMID 24255920 DOI: 10.1182/Blood-2013-05-500272  0.72
2013 Sharma R, Wu X, Rhodes SD, Chen S, He Y, Yuan J, Li J, Yang X, Li X, Jiang L, Kim ET, Stevenson DA, Viskochil D, Xu M, Yang FC. Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice. Human Molecular Genetics. 22: 4818-28. PMID 23863460 DOI: 10.1093/Hmg/Ddt333  0.72
2013 Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, ... ... Yang FC, et al. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America. 110: 11994-9. PMID 23818607 DOI: 10.1073/Pnas.1310656110  0.72
2013 Nalepa G, Barnholtz-Sloan J, Enzor R, Dey D, He Y, Gehlhausen JR, Lehmann AS, Park SJ, Yang Y, Yang X, Chen S, Guan X, Chen Y, Renbarger J, Yang FC, et al. The tumor suppressor CDKN3 controls mitosis. The Journal of Cell Biology. 201: 997-1012. PMID 23775190 DOI: 10.1083/Jcb.201205125  0.72
2013 Rhodes SD, Wu X, He Y, Chen S, Yang H, Staser KW, Wang J, Zhang P, Jiang C, Yokota H, Dong R, Peng X, Yang X, Murthy S, Azhar M, ... ... Yang FC, et al. Hyperactive transforming growth factor-β1 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2476-89. PMID 23703870 DOI: 10.1002/Jbmr.1992  0.72
2013 Stevenson DA, Little D, Armstrong L, Crawford AH, Eastwood D, Friedman JM, Greggi T, Gutierrez G, Hunter-Schaedle K, Kendler DL, Kolanczyk M, Monsell F, Oetgen M, Richards BS, Schindeler A, ... ... Yang FC, et al. Approaches to treating NF1 tibial pseudarthrosis: consensus from the Children's Tumor Foundation NF1 Bone Abnormalities Consortium. Journal of Pediatric Orthopedics. 33: 269-75. PMID 23482262 DOI: 10.1097/Bpo.0B013E31828121B8  0.72
2013 Staser K, Park SJ, Rhodes SD, Zeng Y, He YZ, Shew MA, Gehlhausen JR, Cerabona D, Menon K, Chen S, Sun Z, Yuan J, Ingram DA, Nalepa G, Yang FC, et al. Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk. The Journal of Clinical Investigation. 123: 329-34. PMID 23221339 DOI: 10.1172/Jci66167  0.72
2013 He Y, Childress P, Hood M, Alvarez M, Kacena MA, Hanlon M, McKee B, Bidwell JP, Yang FC. Nmp4/CIZ suppresses the parathyroid hormone anabolic window by restricting mesenchymal stem cell and osteoprogenitor frequency. Stem Cells and Development. 22: 492-500. PMID 22873745 DOI: 10.1089/Scd.2012.0308  0.72
2012 He Y, Rhodes SD, Chen S, Wu X, Yuan J, Yang X, Jiang L, Li X, Takahashi N, Xu M, Mohammad KS, Guise TA, Yang FC. c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions. Plos One. 7: e46900. PMID 23144792 DOI: 10.1371/journal.pone.0046900  0.72
2012 Bidwell JP, Childress P, Alvarez MB, Hood M, He Y, Pavalko FM, Kacena MA, Yang FC. Nmp4/CIZ closes the parathyroid hormone anabolic window. Critical Reviews in Eukaryotic Gene Expression. 22: 205-18. PMID 23140162 DOI: 10.1615/Critreveukargeneexpr.V22.I3.40  0.72
2012 Robertson KA, Nalepa G, Yang FC, Bowers DC, Ho CY, Hutchins GD, Croop JM, Vik TA, Denne SC, Parada LF, Hingtgen CM, Walsh LE, Yu M, Pradhan KR, Edwards-Brown MK, et al. Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial. The Lancet. Oncology. 13: 1218-24. PMID 23099009 DOI: 10.1016/S1470-2045(12)70414-X  0.72
2011 Wu X, Chen S, He Y, Rhodes SD, Mohammad KS, Li X, Yang X, Jiang L, Nalepa G, Snider P, Robling AG, Clapp DW, Conway SJ, Guise TA, Yang FC. The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. Plos One. 6: e24917. PMID 21980365 DOI: 10.1371/journal.pone.0024917  0.72
2011 He Y, Staser K, Rhodes SD, Liu Y, Wu X, Park SJ, Yuan J, Yang X, Li X, Jiang L, Chen S, Yang FC. Erk1 positively regulates osteoclast differentiation and bone resorptive activity. Plos One. 6: e24780. PMID 21961044 DOI: 10.1371/journal.pone.0024780  0.72
2011 Li Z, Cai X, Cai CL, Wang J, Zhang W, Petersen BE, Yang FC, Xu M. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood. 118: 4509-18. PMID 21803851 DOI: 10.1182/blood-2010-12-325241  0.72
2011 Yang Z, Chen M, Sitarski SA, Saadatzadeh T, Yin F, Yu M, Yang FC, Chan RJ. Genetic disruption of the scaffolding protein, Kinase Suppressor of Ras 1 (KSR1), differentially regulates GM-CSF-stimulated hyperproliferation in hematopoietic progenitors expressing activating PTPN11 mutants D61Y and E76K. Leukemia Research. 35: 961-4. PMID 21555152 DOI: 10.1016/J.Leukres.2011.04.003  0.72
2011 Zhang W, Rhodes SD, Zhao L, He Y, Zhang Y, Shen Y, Yang D, Wu X, Li X, Yang X, Park SJ, Chen S, Turner C, Yang FC. Primary osteopathy of vertebrae in a neurofibromatosis type 1 murine model. Bone. 48: 1378-87. PMID 21439418 DOI: 10.1016/J.Bone.2011.03.760  0.72
2011 Wu X, Chen S, Orlando SA, Yuan J, Kim ET, Munugalavadla V, Mali RS, Kapur R, Yang FC. p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway. The Journal of Biological Chemistry. 286: 13512-21. PMID 21324896 DOI: 10.1074/jbc.M110.187351  0.72
2011 Stevenson DA, Schwarz EL, Carey JC, Viskochil DH, Hanson H, Bauer S, Weng HY, Greene T, Reinker K, Swensen J, Chan RJ, Yang FC, Senbanjo L, Yang Z, Mao R, et al. Bone resorption in syndromes of the Ras/MAPK pathway. Clinical Genetics. 80: 566-73. PMID 21204800 DOI: 10.1111/J.1399-0004.2010.01619.X  0.72
2010 Hirasawa H, Jiang C, Zhang P, Yang FC, Yokota H. Mechanical stimulation suppresses phosphorylation of eIF2alpha and PERK-mediated responses to stress to the endoplasmic reticulum. Febs Letters. 584: 745-52. PMID 20034494 DOI: 10.1016/J.Febslet.2009.12.028  0.72
2010 Benson EA, Goebl MG, Yang FC, Kapur R, McClintick J, Sanghani S, Clapp DW, Harrington MA. Loss of SIMPL compromises TNF-alpha-dependent survival of hematopoietic progenitors. Experimental Hematology. 38: 71-81. PMID 19941935 DOI: 10.1016/J.Exphem.2009.11.006  0.72
2009 Elefteriou F, Kolanczyk M, Schindeler A, Viskochil DH, Hock JM, Schorry EK, Crawford AH, Friedman JM, Little D, Peltonen J, Carey JC, Feldman D, Yu X, Armstrong L, Birch P, ... ... Yang FC, et al. Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options. American Journal of Medical Genetics. Part A. 149: 2327-38. PMID 19764036 DOI: 10.1002/Ajmg.A.33045  0.72
2009 Goodman ML, Chen S, Yang FC, Chan RJ. Novel method of murine embryonic stem cell-derived osteoclast development. Stem Cells and Development. 18: 195-200. PMID 18616393 DOI: 10.1089/scd.2008.0193  0.72
2008 Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, et al. Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell. 135: 437-48. PMID 18984156 DOI: 10.1016/J.Cell.2008.08.041  0.72
2008 Pulliam AC, Hobson MJ, Ciccone SL, Li Y, Chen S, Srour EF, Yang FC, Broxmeyer HE, Clapp DW. AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice. Experimental Hematology. 36: 1084-90. PMID 18495331 DOI: 10.1016/J.Exphem.2008.03.016  0.72
2008 Yan J, Chen S, Zhang Y, Li X, Li Y, Wu X, Yuan J, Robling AG, Kapur R, Karpur R, Chan RJ, Yang FC. Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. Human Molecular Genetics. 17: 936-48. PMID 18089636 DOI: 10.1093/Hmg/Ddm366  0.72
2007 Li B, Jia N, Waning DL, Yang FC, Haneline LS, Chun KT. Cul4A is required for hematopoietic stem-cell engraftment and self-renewal. Blood. 110: 2704-7. PMID 17616641 DOI: 10.1182/Blood-2006-12-064154  0.72
2007 Khalaf WF, Yang FC, Chen S, White H, Bessler W, Ingram DA, Clapp DW. K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 2527-34. PMID 17277161  0.72
2006 Si Y, Ciccone S, Yang FC, Yuan J, Zeng D, Chen S, van de Vrugt HJ, Critser J, Arwert F, Haneline LS, Clapp DW. Continuous in vivo infusion of interferon-gamma (IFN-gamma) enhances engraftment of syngeneic wild-type cells in Fanca-/- and Fancg-/- mice. Blood. 108: 4283-7. PMID 16946306 DOI: 10.1182/Blood-2006-03-007997  0.72
2006 Yang FC, Chen S, Clegg T, Li X, Morgan T, Estwick SA, Yuan J, Khalaf W, Burgin S, Travers J, Parada LF, Ingram DA, Clapp DW. Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. Human Molecular Genetics. 15: 2421-37. PMID 16835260 DOI: 10.1093/hmg/ddl165  0.72
2006 Haneline LS, White H, Yang FC, Chen S, Orschell C, Kapur R, Ingram DA. Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo. Blood. 107: 1375-82. PMID 16239435 DOI: 10.1182/Blood-2005-05-1985  0.72
2005 Jansen M, Yang FC, Cancelas JA, Bailey JR, Williams DA. Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure. Stem Cells (Dayton, Ohio). 23: 335-46. PMID 15749928 DOI: 10.1634/stemcells.2004-0216  0.72
2005 Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy. Blood. 105: 3465-71. PMID 15644418 DOI: 10.1182/Blood-2004-06-2483  0.72
2003 Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. The Journal of Clinical Investigation. 112: 1851-61. PMID 14679180 DOI: 10.1172/Jci19195  0.72
2001 Yang FC, Atkinson SJ, Gu Y, Borneo JB, Roberts AW, Zheng Y, Pennington J, Williams DA. Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization Proceedings of the National Academy of Sciences of the United States of America. 98: 5614-5618. PMID 11320224 DOI: 10.1073/Pnas.101546898  0.72
2000 Ingram DA, Yang FC, Travers JB, Wenning MJ, Hiatt K, New S, Hood A, Shannon K, Williams DA, Clapp DW. Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo Journal of Experimental Medicine. 191: 181-187. PMID 10620616 DOI: 10.1084/Jem.191.1.181  0.72
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