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Kathleen L. Gabrielson, Ph.D. - Publications

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
Toxicology
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Miles D, Sforza D, Wong JW, Gabrielson K, Aziz K, Mahesh M, Coulter JB, Siddiqui I, Tran PT, Viswanathan AN, Rezaee M. FLASH Effects Induced by Orthovoltage X-Rays: FLASH with x-ray tubes - an in vivo study. International Journal of Radiation Oncology, Biology, Physics. PMID 37364800 DOI: 10.1016/j.ijrobp.2023.06.006  0.61
2020 Ito T, Saeki H, Guo X, Sysa-Shah P, Coulter J, Tamashiro K, Lee RS, Orita H, Sato K, Ishiyama S, Hulbert A, Smith WE, Peterson LA, Brock MV, Gabrielson KL. Prenatal stress enhances NNK-induced lung tumors in A/J mice. Carcinogenesis. PMID 32249286 DOI: 10.1093/Carcin/Bgaa033  0.656
2019 Oei AL, Korangath P, Mulka K, Helenius M, Coulter JB, Stewart J, Velarde E, Crezee J, Simons B, Stalpers LJA, Kok HP, Gabrielson K, Franken NAP, Ivkov R. Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer. International Journal of Hyperthermia : the Official Journal of European Society For Hyperthermic Oncology, North American Hyperthermia Group. 36: 47-63. PMID 31795835 DOI: 10.1080/02656736.2019.1685686  0.647
2019 Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE. BLT-immune humanized mice as a model for nivolumab induced immune-mediated adverse events: Comparison of the NOG and NOG-EXL strains. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30850839 DOI: 10.1093/Toxsci/Kfz045  0.322
2014 Sysa-Shah P, Xu Y, Guo X, Pin S, Bedja D, Bartock R, Tsao A, Hsieh A, Wolin MS, Moens A, Raman V, Orita H, Gabrielson KL. Geranylgeranylacetone blocks doxorubicin-induced cardiac toxicity and reduces cancer cell growth and invasion through RHO pathway inhibition. Molecular Cancer Therapeutics. 13: 1717-28. PMID 24737026 DOI: 10.1158/1535-7163.Mct-13-0965  0.391
2014 Auer DR, Sysa-Shah P, Bedja D, Simmers JL, Pak E, Dutra A, Cohn R, Gabrielson KL, Chakravarti A, Kapoor A. Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse. Biotechnology Letters. 36: 1179-85. PMID 24563304 DOI: 10.1007/S10529-014-1473-X  0.325
2014 Kaludercic N, Carpi A, Nagayama T, Sivakumaran V, Zhu G, Lai EW, Bedja D, De Mario A, Chen K, Gabrielson KL, Lindsey ML, Pacak K, Takimoto E, Shih JC, Kass DA, et al. Monoamine oxidase B prompts mitochondrial and cardiac dysfunction in pressure overloaded hearts. Antioxidants & Redox Signaling. 20: 267-80. PMID 23581564 DOI: 10.1089/Ars.2012.4616  0.329
2013 Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Fairweather D, Bedja D, Stickel NR, Fontes JA, Cardamone AB, Zheng D, Gabrielson KL, Rose NR, Ciháková D. Fatal eosinophilic myocarditis develops in the absence of IFN-γ and IL-17A. Journal of Immunology (Baltimore, Md. : 1950). 191: 4038-47. PMID 24048893 DOI: 10.4049/Jimmunol.1301282  0.311
2013 Yap KL, Sysa-Shah P, Bolon B, Wu RC, Gao M, Herlinger AL, Wang F, Faiola F, Huso D, Gabrielson K, Wang TL, Wang J, Shih IeM. Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis. Plos One. 8: e69099. PMID 23922682 DOI: 10.1371/Journal.Pone.0069099  0.305
2013 AlGhatrif M, Watts VL, Niu X, Halushka M, Miller KL, Vandegaer K, Bedja D, Fox-Talbot K, Bielawska A, Gabrielson KL, Barouch LA. Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity. Journal of Cardiovascular Translational Research. 6: 436-45. PMID 23456569 DOI: 10.1007/S12265-013-9453-4  0.301
2013 Abston ED, Coronado MJ, Bucek A, Onyimba JA, Brandt JE, Frisancho JA, Kim E, Bedja D, Sung YK, Radtke AJ, Gabrielson KL, Mitzner W, Fairweather D. TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R267-77. PMID 23255589 DOI: 10.1152/Ajpregu.00516.2011  0.319
2013 Sikka G, Miller KL, Steppan J, Pandey D, Jung SM, Fraser CD, Ellis C, Ross D, Vandegaer K, Bedja D, Gabrielson K, Walston JD, Berkowitz DE, Barouch LA. Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age. Experimental Gerontology. 48: 128-35. PMID 23159957 DOI: 10.1016/J.Exger.2012.11.001  0.3
2012 Sysa-Shah P, Xu Y, Guo X, Belmonte F, Kang B, Bedja D, Pin S, Tsuchiya N, Gabrielson K. Cardiac-specific over-expression of epidermal growth factor receptor 2 (ErbB2) induces pro-survival pathways and hypertrophic cardiomyopathy in mice. Plos One. 7: e42805. PMID 22912742 DOI: 10.1371/Journal.Pone.0042805  0.356
2012 Octavia Y, Tocchetti CG, Gabrielson KL, Janssens S, Crijns HJ, Moens AL. Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies. Journal of Molecular and Cellular Cardiology. 52: 1213-25. PMID 22465037 DOI: 10.1016/J.Yjmcc.2012.03.006  0.306
2012 Wei H, Bedja D, Koitabashi N, Xing D, Chen J, Fox-Talbot K, Rouf R, Chen S, Steenbergen C, Harmon JW, Dietz HC, Gabrielson KL, Kass DA, Semenza GL. Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: E841-50. PMID 22403061 DOI: 10.1073/Pnas.1202081109  0.35
2012 Coronado MJ, Brandt JE, Kim E, Bucek A, Bedja D, Abston ED, Shin J, Gabrielson KL, Mitzner W, Fairweather D. Testosterone and interleukin-1β increase cardiac remodeling during coxsackievirus B3 myocarditis via serpin A 3n. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1726-36. PMID 22328081 DOI: 10.1152/Ajpheart.00783.2011  0.309
2012 Abston ED, Coronado MJ, Bucek A, Bedja D, Shin J, Kim JB, Kim E, Gabrielson KL, Georgakopoulos D, Mitzner W, Fairweather D. Th2 regulation of viral myocarditis in mice: different roles for TLR3 versus TRIF in progression to chronic disease. Clinical & Developmental Immunology. 2012: 129486. PMID 22013485 DOI: 10.1155/2012/129486  0.317
2011 Onyimba JA, Coronado MJ, Garton AE, Kim JB, Bucek A, Bedja D, Gabrielson KL, Guilarte TR, Fairweather D. The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice. Biology of Sex Differences. 2: 2. PMID 21338512 DOI: 10.1186/2042-6410-2-2  0.303
2010 Zhang M, Takimoto E, Hsu S, Lee DI, Nagayama T, Danner T, Koitabashi N, Barth AS, Bedja D, Gabrielson KL, Wang Y, Kass DA. Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. Journal of the American College of Cardiology. 56: 2021-30. PMID 20970280 DOI: 10.1016/J.Jacc.2010.08.612  0.341
2010 Zu L, Bedja D, Fox-Talbot K, Gabrielson KL, Van Kaer L, Becker LC, Cai ZP. Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice. Journal of Molecular and Cellular Cardiology. 49: 5-15. PMID 20153750 DOI: 10.1016/J.Yjmcc.2010.02.007  0.305
2010 Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N. Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload. Circulation Research. 106: 193-202. PMID 19910579 DOI: 10.1161/Circresaha.109.198366  0.346
2009 Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK, Champion HC, Bedja D, Gabrielson KL, Chen J, Xia Y, Hale AB, Channon KM, Halushka MK, Barker N, et al. Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor. Journal of Molecular and Cellular Cardiology. 47: 576-85. PMID 19766235 DOI: 10.1016/J.Yjmcc.2009.06.005  0.305
2009 Koitabashi N, Bedja D, Zaiman AL, Pinto YM, Zhang M, Gabrielson KL, Takimoto E, Kass DA. Avoidance of transient cardiomyopathy in cardiomyocyte-targeted tamoxifen-induced MerCreMer gene deletion models. Circulation Research. 105: 12-5. PMID 19520971 DOI: 10.1161/Circresaha.109.198416  0.316
2009 Nagayama T, Hsu S, Zhang M, Koitabashi N, Bedja D, Gabrielson KL, Takimoto E, Kass DA. Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition. Journal of Molecular and Cellular Cardiology. 46: 560-7. PMID 19159628 DOI: 10.1016/J.Yjmcc.2008.12.008  0.312
2009 Nagayama T, Hsu S, Zhang M, Koitabashi N, Bedja D, Gabrielson KL, Takimoto E, Kass DA. Sildenafil stops progressive chamber, cellular, and molecular remodeling and improves calcium handling and function in hearts with pre-existing advanced hypertrophy caused by pressure overload. Journal of the American College of Cardiology. 53: 207-15. PMID 19130990 DOI: 10.1016/J.Jacc.2008.08.069  0.34
2009 Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. The Journal of Clinical Investigation. 119: 408-20. PMID 19127022 DOI: 10.1172/Jci35620  0.346
2009 Sussan TE, Rangasamy T, Blake DJ, Malhotra D, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, et al. Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 250-5. PMID 19104057 DOI: 10.1073/Pnas.0804333106  0.334
2009 Hsu S, Nagayama T, Koitabashi N, Zhang M, Zhou L, Bedja D, Gabrielson KL, Molkentin JD, Kass DA, Takimoto E. Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway. Cardiovascular Research. 81: 301-9. PMID 19029137 DOI: 10.1093/Cvr/Cvn324  0.306
2009 Leyton-Mange JS, Niu X, Yang R, Miller KL, Moens AL, Hale AB, Bedja D, Gabrielson KL, Channon KM, Kass DA, Barouch LA. Tetrahydrobiopterin Rescues β3-/- Mice from Cardiac Hypertrophy and Impaired Function Induced by Pressure Overload Journal of Cardiac Failure. 15. DOI: 10.1016/J.Cardfail.2009.06.428  0.314
2008 Sussan TE, Jun J, Thimmulappa R, Bedja D, Antero M, Gabrielson KL, Polotsky VY, Biswal S. Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice. Plos One. 3: e3791. PMID 19023427 DOI: 10.1371/Journal.Pone.0003791  0.308
2008 Feldmann G, Fendrich V, McGovern K, Bedja D, Bisht S, Alvarez H, Koorstra JB, Habbe N, Karikari C, Mullendore M, Gabrielson KL, Sharma R, Matsui W, Maitra A. An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Molecular Cancer Therapeutics. 7: 2725-35. PMID 18790753 DOI: 10.1158/1535-7163.Mct-08-0573  0.303
2008 Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G, Ketner EA, Majmudar M, Gabrielson K, Halushka MK, Mitchell JB, Biswal S, Channon KM, Wolin MS, Alp NJ, et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation. 117: 2626-36. PMID 18474817 DOI: 10.1161/Circulationaha.107.737031  0.349
2008 Tankersley CG, Champion HC, Takimoto E, Gabrielson K, Bedja D, Misra V, El-Haddad H, Rabold R, Mitzner W. Exposure to inhaled particulate matter impairs cardiac function in senescent mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R252-63. PMID 18448608 DOI: 10.1152/Ajpregu.00697.2007  0.328
2007 Gabrielson K, Bedja D, Pin S, Tsao A, Gama L, Yuan B, Muratore N. Heat shock protein 90 and ErbB2 in the cardiac response to doxorubicin injury. Cancer Research. 67: 1436-41. PMID 17308081 DOI: 10.1158/0008-5472.Can-06-3721  0.321
2006 Lehrke S, Mazhari R, Durand DJ, Zheng M, Bedja D, Zimmet JM, Schuleri KH, Chi AS, Gabrielson KL, Hare JM. Aging impairs the beneficial effect of granulocyte colony-stimulating factor and stem cell factor on post-myocardial infarction remodeling. Circulation Research. 99: 553-60. PMID 16873716 DOI: 10.1161/01.Res.0000238375.88582.D8  0.304
2006 Raju SV, Zheng M, Schuleri KH, Phan AC, Bedja D, Saraiva RM, Yiginer O, Vandegaer K, Gabrielson KL, O'donnell CP, Berkowitz DE, Barouch LA, Hare JM. Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity. Proceedings of the National Academy of Sciences of the United States of America. 103: 4222-7. PMID 16537512 DOI: 10.1073/Pnas.0510460103  0.322
2005 Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. The Journal of Clinical Investigation. 115: 1221-31. PMID 15841206 DOI: 10.1172/Jci21968  0.352
2005 Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nature Medicine. 11: 214-22. PMID 15665834 DOI: 10.1038/Nm1175  0.325
2001 Gabrielson KL, Hogue BA, Bohr VA, Cardounel AJ, Nakajima W, Kofler J, Zweier JL, Rodriguez ER, Martin LJ, de Souza-Pinto NC, Bressler J. Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice. The American Journal of Pathology. 159: 1507-20. PMID 11583977 DOI: 10.1016/S0002-9440(10)62536-9  0.627
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