| Year |
Citation |
Score |
| 2022 |
Reilly PF, Tjahjadi A, Miller SL, Akey JM, Tucci S. The contribution of Neanderthal introgression to modern human traits. Current Biology : Cb. 32: R970-R983. PMID 36167050 DOI: 10.1016/j.cub.2022.08.027 |
0.423 |
|
| 2021 |
Xu H, Zhen Q, Bai M, Fang L, Zhang Y, Li B, Ge H, Moon S, Chen W, Fu W, Xu Q, Zhou Y, Yu Y, Lin L, Yong L, ... ... Akey JM, et al. Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals. Genome Research. PMID 34155038 DOI: 10.1101/gr.267963.120 |
0.419 |
|
| 2020 |
Akey J, Tishkoff S. Editorial overview: Evolutionary genomics - from molecular mechanisms to phenotypes to populations. Current Opinion in Genetics & Development. 62: iii-iv. PMID 32892943 DOI: 10.1016/J.Gde.2020.08.001 |
0.495 |
|
| 2020 |
Chen L, Wolf AB, Fu W, Li L, Akey JM. Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals. Cell. PMID 32004458 DOI: 10.1016/j.cell.2020.01.012 |
0.421 |
|
| 2018 |
Tucci S, Vohr SH, McCoy RC, Vernot B, Robinson MR, Barbieri C, Nelson BJ, Fu W, Purnomo GA, Sudoyo H, Eichler EE, Barbujani G, Visscher PM, Akey JM, Green RE. Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science (New York, N.Y.). 361: 511-516. PMID 30072539 DOI: 10.1126/science.aar8486 |
0.479 |
|
| 2018 |
Press MO, McCoy RC, Hall AN, Akey JM, Queitsch C. Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana. Genome Research. PMID 29970452 DOI: 10.1101/Gr.231753.117 |
0.356 |
|
| 2018 |
Wolf AB, Akey JM. Outstanding questions in the study of archaic hominin admixture. Plos Genetics. 14: e1007349. PMID 29852022 DOI: 10.1371/journal.pgen.1007349 |
0.312 |
|
| 2018 |
Jin Y, Gittelman RM, Lu Y, Liu X, Li MD, Ling F, Akey JM. Evolution of DNAaseI Hypersensitive Sites in MHC Regulatory Regions of Primates. Genetics. PMID 29669733 DOI: 10.1534/genetics.118.301028 |
0.467 |
|
| 2018 |
Browning SR, Browning BL, Zhou Y, Tucci S, Akey JM. Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture. Cell. PMID 29551270 DOI: 10.1016/J.Cell.2018.02.031 |
0.406 |
|
| 2017 |
McCoy RC, Akey JM. Selection plays the hand it was dealt: evidence that human adaptation commonly targets standing genetic variation. Genome Biology. 18: 139. PMID 28760139 DOI: 10.1186/s13059-017-1280-5 |
0.364 |
|
| 2017 |
McCoy RC, Wakefield J, Akey JM. Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression. Cell. 168: 916-927.e12. PMID 28235201 DOI: 10.1016/J.Cell.2017.01.038 |
0.439 |
|
| 2017 |
Nielsen R, Akey JM, Jakobsson M, Pritchard JK, Tishkoff S, Willerslev E. Tracing the peopling of the world through genomics. Nature. 541: 302-310. PMID 28102248 DOI: 10.1038/Nature21347 |
0.406 |
|
| 2016 |
Akey JM, Di Rienzo A. Editorial overview: Genetics of human origin: New horizons in human population genetics. Current Opinion in Genetics & Development. PMID 27889118 DOI: 10.1016/j.gde.2016.11.002 |
0.307 |
|
| 2016 |
Fu W, Ligabue A, Rogers KJ, Akey JM, Monnat RJ. Human RECQ Helicase Pathogenic Variants, Population Variation and 'Missing' Diseases. Human Mutation. PMID 27859906 DOI: 10.1002/Humu.23148 |
0.337 |
|
| 2016 |
Gittelman RM, Schraiber JG, Vernot B, Mikacenic C, Wurfel MM, Akey JM. Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments. Current Biology : Cb. PMID 27839976 DOI: 10.1016/J.Cub.2016.10.041 |
0.774 |
|
| 2016 |
Fu W, Browning SR, Browning BL, Akey JM. Robust Inference of Identity by Descent from Exome-Sequencing Data. American Journal of Human Genetics. PMID 27745837 DOI: 10.1016/J.Ajhg.2016.09.011 |
0.382 |
|
| 2016 |
Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, ... ... Akey J, et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 7: 12522. PMID 27725671 DOI: 10.1038/Ncomms12522 |
0.54 |
|
| 2016 |
Nuttle X, Giannuzzi G, Duyzend MH, Schraiber JG, Narvaiza I, Sudmant PH, Penn O, Chiatante G, Malig M, Huddleston J, Benner C, Camponeschi F, Ciofi-Baffoni S, Stessman HA, Marchetto MC, ... ... Akey JM, et al. Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility. Nature. PMID 27487209 DOI: 10.1038/Nature19075 |
0.744 |
|
| 2016 |
Moon S, Akey JM. A flexible method for estimating the fraction of fitness influencing mutations from large sequencing data sets. Genome Research. PMID 27197222 DOI: 10.1101/gr.203059.115 |
0.325 |
|
| 2016 |
Vernot B, Tucci S, Kelso J, Schraiber JG, Wolf AB, Gittelman RM, Dannemann M, Grote S, McCoy RC, Norton H, Scheinfeldt LB, Merriwether DA, Koki G, Friedlaender JS, Wakefield J, ... ... Akey JM, et al. Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals. Science (New York, N.Y.). PMID 26989198 DOI: 10.1126/Science.Aad9416 |
0.74 |
|
| 2016 |
Simonti CN, Vernot B, Bastarache L, Bottinger E, Carrell DS, Chisholm RL, Crosslin DR, Hebbring SJ, Jarvik GP, Kullo IJ, Li R, Pathak J, Ritchie MD, Roden DM, Verma SS, ... ... Akey JM, et al. The phenotypic legacy of admixture between modern humans and Neandertals. Science (New York, N.Y.). 351: 737-41. PMID 26912863 DOI: 10.1126/Science.Aad2149 |
0.34 |
|
| 2015 |
Schraiber JG, Akey JM. Methods and models for unravelling human evolutionary history. Nature Reviews. Genetics. PMID 26553329 DOI: 10.1038/Nrg4005 |
0.743 |
|
| 2015 |
Vattathil S, Akey JM. Small Amounts of Archaic Admixture Provide Big Insights into Human History. Cell. 163: 281-4. PMID 26451479 DOI: 10.1016/j.cell.2015.09.042 |
0.325 |
|
| 2015 |
Gittelman RM, Hun E, Ay F, Madeoy J, Pennacchio L, Noble WS, Hawkins DR, Akey JM. Comprehensive identification and analysis of human accelerated regulatory DNA. Genome Research. PMID 26104583 DOI: 10.1101/Gr.192591.115 |
0.403 |
|
| 2015 |
Vernot B, Akey JM. Complex history of admixture between modern humans and Neandertals. American Journal of Human Genetics. 96: 448-53. PMID 25683119 DOI: 10.1016/j.ajhg.2015.01.006 |
0.422 |
|
| 2015 |
Emery LS, Magnaye KM, Bigham AW, Akey JM, Bamshad MJ. Estimates of continental ancestry vary widely among individuals with the same mtDNA haplogroup. American Journal of Human Genetics. 96: 183-93. PMID 25620206 DOI: 10.1016/j.ajhg.2014.12.015 |
0.401 |
|
| 2015 |
O'Connor TD, Fu W, Mychaleckyj JC, Logsdon B, Auer P, Carlson CS, Leal SM, Smith JD, Rieder MJ, Bamshad MJ, Nickerson DA, Akey JM. Rare variation facilitates inferences of fine-scale population structure in humans. Molecular Biology and Evolution. 32: 653-60. PMID 25415970 DOI: 10.1093/Molbev/Msu326 |
0.348 |
|
| 2014 |
Fu W, Gittelman RM, Bamshad MJ, Akey JM. Characteristics of neutral and deleterious protein-coding variation among individuals and populations. American Journal of Human Genetics. 95: 421-36. PMID 25279984 DOI: 10.1016/j.ajhg.2014.09.006 |
0.405 |
|
| 2014 |
Andrie JM, Wakefield J, Akey JM. Heritable variation of mRNA decay rates in yeast. Genome Research. 24: 2000-10. PMID 25258386 DOI: 10.1101/Gr.175802.114 |
0.322 |
|
| 2014 |
Vernot B, Akey JM. Human evolution: genomic gifts from archaic hominins. Current Biology : Cb. 24: R845-8. PMID 25247359 DOI: 10.1016/j.cub.2014.07.079 |
0.375 |
|
| 2014 |
Rogers KJ, Fu W, Akey JM, Monnat RJ. Global and disease-associated genetic variation in the human Fanconi anemia gene family. Human Molecular Genetics. 23: 6815-25. PMID 25104853 DOI: 10.1093/Hmg/Ddu400 |
0.417 |
|
| 2014 |
Connelly CF, Wakefield J, Akey JM. Evolution and genetic architecture of chromatin accessibility and function in yeast. Plos Genetics. 10: e1004427. PMID 24992477 DOI: 10.1371/Journal.Pgen.1004427 |
0.736 |
|
| 2014 |
Vernot B, Akey JM. Resurrecting surviving Neandertal lineages from modern human genomes. Science (New York, N.Y.). 343: 1017-21. PMID 24476670 DOI: 10.1126/science.1245938 |
0.415 |
|
| 2013 |
Zhang G, Muglia LJ, Chakraborty R, Akey JM, Williams SM. Signatures of natural selection on genetic variants affecting complex human traits. Applied & Translational Genomics. 2: 78-94. PMID 27896059 DOI: 10.1016/J.Atg.2013.10.002 |
0.393 |
|
| 2013 |
Stergachis AB, Haugen E, Shafer A, Fu W, Vernot B, Reynolds A, Raubitschek A, Ziegler S, LeProust EM, Akey JM, Stamatoyannopoulos JA. Exonic transcription factor binding directs codon choice and affects protein evolution. Science (New York, N.Y.). 342: 1367-72. PMID 24337295 DOI: 10.1126/Science.1243490 |
0.328 |
|
| 2013 |
Fu W, O'Connor TD, Akey JM. Genetic architecture of quantitative traits and complex diseases. Current Opinion in Genetics & Development. 23: 678-83. PMID 24287334 DOI: 10.1016/j.gde.2013.10.008 |
0.399 |
|
| 2013 |
O'Connor TD, Kiezun A, Bamshad M, Rich SS, Smith JD, Turner E, Leal SM, Akey JM. Fine-scale patterns of population stratification confound rare variant association tests. Plos One. 8: e65834. PMID 23861739 DOI: 10.1371/Journal.Pone.0065834 |
0.331 |
|
| 2013 |
Hider JL, Gittelman RM, Shah T, Edwards M, Rosenbloom A, Akey JM, Parra EJ. Exploring signatures of positive selection in pigmentation candidate genes in populations of East Asian ancestry. Bmc Evolutionary Biology. 13: 150. PMID 23848512 DOI: 10.1186/1471-2148-13-150 |
0.45 |
|
| 2013 |
Fu W, Akey JM. Selection and adaptation in the human genome. Annual Review of Genomics and Human Genetics. 14: 467-89. PMID 23834317 DOI: 10.1146/annurev-genom-091212-153509 |
0.447 |
|
| 2013 |
Prado-Martinez J, Sudmant PH, Kidd JM, Li H, Kelley JL, Lorente-Galdos B, Veeramah KR, Woerner AE, O'Connor TD, Santpere G, Cagan A, Theunert C, Casals F, Laayouni H, Munch K, ... ... Akey JM, et al. Great ape genetic diversity and population history. Nature. 499: 471-5. PMID 23823723 DOI: 10.1038/Nature12228 |
0.404 |
|
| 2013 |
Duggal NK, Fu W, Akey JM, Emerman M. Identification and antiviral activity of common polymorphisms in the APOBEC3 locus in human populations. Virology. 443: 329-37. PMID 23755966 DOI: 10.1016/J.Virol.2013.05.016 |
0.364 |
|
| 2013 |
Skelly DA, Merrihew GE, Riffle M, Connelly CF, Kerr EO, Johansson M, Jaschob D, Graczyk B, Shulman NJ, Wakefield J, Cooper SJ, Fields S, Noble WS, Muller EG, Davis TN, ... ... Akey JM, et al. Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast. Genome Research. 23: 1496-504. PMID 23720455 DOI: 10.1101/Gr.155762.113 |
0.783 |
|
| 2013 |
Connelly CF, Skelly DA, Dunham MJ, Akey JM. Population genomics and transcriptional consequences of regulatory motif variation in globally diverse Saccharomyces cerevisiae strains. Molecular Biology and Evolution. 30: 1605-13. PMID 23619145 DOI: 10.1093/Molbev/Mst073 |
0.814 |
|
| 2013 |
Fu W, O'Connor TD, Jun G, Kang HM, Abecasis G, Leal SM, Gabriel S, Rieder MJ, Altshuler D, Shendure J, Nickerson DA, Bamshad MJ, Akey JM. Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants. Nature. 493: 216-20. PMID 23201682 DOI: 10.1038/Nature11690 |
0.375 |
|
| 2013 |
Zhang G, Muglia LJ, Chakraborty R, Akey JM, Williams SM. Signatures of natural selection on genetic variants affecting complex human traits Applied and Translational Genomics. 2: 77-93. DOI: 10.1016/j.atg.2013.10.002 |
0.337 |
|
| 2012 |
Wong AK, Ruhe AL, Biswas S, Robertson KR, Ali A, Akey JM, Neff MW. Marker panels for genealogy-based mapping, breed demographics, and inference-of-ancestry in the dog. Animal Biotechnology. 23: 241-52. PMID 23134304 DOI: 10.1080/10495398.2012.717151 |
0.684 |
|
| 2012 |
Vernot B, Stergachis AB, Maurano MT, Vierstra J, Neph S, Thurman RE, Stamatoyannopoulos JA, Akey JM. Personal and population genomics of human regulatory variation. Genome Research. 22: 1689-97. PMID 22955981 DOI: 10.1101/Gr.134890.111 |
0.436 |
|
| 2012 |
Neph S, Vierstra J, Stergachis AB, Reynolds AP, Haugen E, Vernot B, Thurman RE, John S, Sandstrom R, Johnson AK, Maurano MT, Humbert R, Rynes E, Wang H, Vong S, ... ... Akey JM, et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature. 489: 83-90. PMID 22955618 DOI: 10.1038/Nature11212 |
0.368 |
|
| 2012 |
Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, Haugen E, Sheffield NC, Stergachis AB, Wang H, Vernot B, Garg K, John S, Sandstrom R, Bates D, Boatman L, ... ... Akey JM, et al. The accessible chromatin landscape of the human genome. Nature. 489: 75-82. PMID 22955617 DOI: 10.1038/Nature11232 |
0.311 |
|
| 2012 |
Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, Zhang K, Akey JM, Tishkoff SA. Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell. 150: 457-69. PMID 22840920 DOI: 10.1016/J.Cell.2012.07.009 |
0.461 |
|
| 2012 |
Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI. Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proceedings of the National Academy of Sciences of the United States of America. 109: E2343-52. PMID 22837397 DOI: 10.1073/Pnas.1206701109 |
0.315 |
|
| 2012 |
Connelly CF, Akey JM. On the prospects of whole-genome association mapping in Saccharomyces cerevisiae. Genetics. 191: 1345-53. PMID 22673807 DOI: 10.1534/Genetics.112.141168 |
0.778 |
|
| 2012 |
Tennessen JA, Bigham AW, O'Connor TD, Fu W, Kenny EE, Gravel S, McGee S, Do R, Liu X, Jun G, Kang HM, Jordan D, Leal SM, Gabriel S, Rieder MJ, ... ... Akey JM, et al. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (New York, N.Y.). 337: 64-9. PMID 22604720 DOI: 10.1126/Science.1219240 |
0.4 |
|
| 2012 |
Christie JD, Wurfel MM, Feng R, O'Keefe GE, Bradfield J, Ware LB, Christiani DC, Calfee CS, Cohen MJ, Matthay M, Meyer NJ, Kim C, Li M, Akey J, Barnes KC, et al. Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. Plos One. 7: e28268. PMID 22295056 DOI: 10.1371/Journal.Pone.0028268 |
0.403 |
|
| 2012 |
Alvarez CE, Akey JM. Copy number variation in the domestic dog. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 144-63. PMID 22138850 DOI: 10.1007/S00335-011-9369-8 |
0.413 |
|
| 2011 |
Scheinfeldt LB, Biswas S, Madeoy J, Connelly CF, Akey JM. Clusters of adaptive evolution in the human genome. Frontiers in Genetics. 2: 50. PMID 22303346 DOI: 10.3389/Fgene.2011.00050 |
0.798 |
|
| 2011 |
Akey JM, Shriver MD. A Grand Challenge in Evolutionary and Population Genetics: New Paradigms for Exploring the Past and Charting the Future in the Post-Genomic era. Frontiers in Genetics. 2: 47. PMID 22303343 DOI: 10.3389/fgene.2011.00047 |
0.404 |
|
| 2011 |
Tennessen JA, O'Connor TD, Bamshad MJ, Akey JM. The promise and limitations of population exomics for human evolution studies. Genome Biology. 12: 127. PMID 21920050 DOI: 10.1186/Gb-2011-12-9-127 |
0.396 |
|
| 2011 |
Skelly DA, Johansson M, Madeoy J, Wakefield J, Akey JM. A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-seq data. Genome Research. 21: 1728-37. PMID 21873452 DOI: 10.1101/Gr.119784.110 |
0.769 |
|
| 2011 |
Nicholas TJ, Baker C, Eichler EE, Akey JM. A high-resolution integrated map of copy number polymorphisms within and between breeds of the modern domesticated dog. Bmc Genomics. 12: 414. PMID 21846351 DOI: 10.1186/1471-2164-12-414 |
0.789 |
|
| 2011 |
Tennessen JA, Akey JM. Parallel adaptive divergence among geographically diverse human populations. Plos Genetics. 7: e1002127. PMID 21698142 DOI: 10.1371/Journal.Pgen.1002127 |
0.46 |
|
| 2011 |
Akey J. Analysis of 2,440 human exomes highlights the evolution and functional impact of rare coding variation Genome Biology. 12. DOI: 10.1186/Gb-2011-12-S1-I1 |
0.533 |
|
| 2010 |
Bigham A, Bauchet M, Pinto D, Mao X, Akey JM, Mei R, Scherer SW, Julian CG, Wilson MJ, López Herráez D, Brutsaert T, Parra EJ, Moore LG, Shriver MD. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data. Plos Genetics. 6: e1001116. PMID 20838600 DOI: 10.1371/Journal.Pgen.1001116 |
0.481 |
|
| 2010 |
Tennessen JA, Madeoy J, Akey JM. Signatures of positive selection apparent in a small sample of human exomes. Genome Research. 20: 1327-34. PMID 20693481 DOI: 10.1101/Gr.106161.110 |
0.498 |
|
| 2010 |
Lambert CA, Connelly CF, Madeoy J, Qiu R, Olson MV, Akey JM. Highly punctuated patterns of population structure on the X chromosome and implications for African evolutionary history. American Journal of Human Genetics. 86: 34-44. PMID 20085712 DOI: 10.1016/J.Ajhg.2009.12.002 |
0.692 |
|
| 2010 |
Akey JM, Ruhe AL, Akey DT, Wong AK, Connelly CF, Madeoy J, Nicholas TJ, Neff MW. Tracking footprints of artificial selection in the dog genome. Proceedings of the National Academy of Sciences of the United States of America. 107: 1160-5. PMID 20080661 DOI: 10.1073/Pnas.0909918107 |
0.808 |
|
| 2009 |
Skelly DA, Ronald J, Connelly CF, Akey JM. Population genomics of intron splicing in 38 Saccharomyces cerevisiae genome sequences. Genome Biology and Evolution. 1: 466-78. PMID 20333215 DOI: 10.1093/Gbe/Evp046 |
0.817 |
|
| 2009 |
Bigham AW, Mao X, Mei R, Brutsaert T, Wilson MJ, Julian CG, Parra EJ, Akey JM, Moore LG, Shriver MD. Identifying positive selection candidate loci for high-altitude adaptation in Andean populations. Human Genomics. 4: 79-90. PMID 20038496 DOI: 10.1186/1479-7364-4-2-79 |
0.453 |
|
| 2009 |
Ko DC, Shukla KP, Fong C, Wasnick M, Brittnacher MJ, Wurfel MM, Holden TD, O'Keefe GE, Van Yserloo B, Akey JM, Miller SI. A genome-wide in vitro bacterial-infection screen reveals human variation in the host response associated with inflammatory disease. American Journal of Human Genetics. 85: 214-27. PMID 19664744 DOI: 10.1016/J.Ajhg.2009.07.012 |
0.384 |
|
| 2009 |
Skelly DA, Ronald J, Akey JM. Inherited variation in gene expression. Annual Review of Genomics and Human Genetics. 10: 313-32. PMID 19630563 DOI: 10.1146/Annurev-Genom-082908-150121 |
0.775 |
|
| 2009 |
Biswas S, Scheinfeldt LB, Akey JM. Genome-wide insights into the patterns and determinants of fine-scale population structure in humans. American Journal of Human Genetics. 84: 641-50. PMID 19442770 DOI: 10.1016/J.Ajhg.2009.04.015 |
0.705 |
|
| 2009 |
Akey JM. Constructing genomic maps of positive selection in humans: where do we go from here? Genome Research. 19: 711-22. PMID 19411596 DOI: 10.1101/gr.086652.108 |
0.473 |
|
| 2009 |
Scheinfeldt LB, Biswas S, Madeoy J, Connelly CF, Schadt EE, Akey JM. Population genomic analysis of ALMS1 in humans reveals a surprisingly complex evolutionary history. Molecular Biology and Evolution. 26: 1357-67. PMID 19279085 DOI: 10.1093/Molbev/Msp045 |
0.792 |
|
| 2009 |
Nicholas TJ, Cheng Z, Ventura M, Mealey K, Eichler EE, Akey JM. The genomic architecture of segmental duplications and associated copy number variants in dogs. Genome Research. 19: 491-9. PMID 19129542 DOI: 10.1101/Gr.084715.108 |
0.79 |
|
| 2009 |
Nicholas TJ, Cheng Z, Mealey KL, Eichler EE, Akey JM. The genomic architecture of segmental duplications and copy number variants in dogs Journal of Veterinary Behavior. 4: 71-72. DOI: 10.1016/J.Jveb.2008.09.037 |
0.734 |
|
| 2008 |
Biswas S, Storey JD, Akey JM. Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis. Bmc Bioinformatics. 9: 244. PMID 18492285 DOI: 10.1186/1471-2105-9-244 |
0.691 |
|
| 2007 |
Ronald J, Akey JM. The evolution of gene expression QTL in Saccharomyces cerevisiae. Plos One. 2: e678. PMID 17668057 DOI: 10.1371/journal.pone.0000678 |
0.437 |
|
| 2007 |
Akey JM, Biswas S, Leek JT, Storey JD. On the design and analysis of gene expression studies in human populations. Nature Genetics. 39: 807-8; author reply . PMID 17597765 DOI: 10.1038/Ng0707-807 |
0.629 |
|
| 2007 |
Storey JD, Madeoy J, Strout JL, Wurfel M, Ronald J, Akey JM. Gene-expression variation within and among human populations. American Journal of Human Genetics. 80: 502-9. PMID 17273971 DOI: 10.1086/512017 |
0.414 |
|
| 2006 |
Kelley JL, Madeoy J, Calhoun JC, Swanson W, Akey JM. Genomic signatures of positive selection in humans and the limits of outlier approaches. Genome Research. 16: 980-9. PMID 16825663 DOI: 10.1101/Gr.5157306 |
0.525 |
|
| 2006 |
Biswas S, Akey JM. Genomic insights into positive selection. Trends in Genetics : Tig. 22: 437-46. PMID 16808986 DOI: 10.1016/J.Tig.2006.06.005 |
0.71 |
|
| 2006 |
Akey JM, Swanson WJ, Madeoy J, Eberle M, Shriver MD. TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations. Human Molecular Genetics. 15: 2106-13. PMID 16717058 DOI: 10.1093/hmg/ddl134 |
0.375 |
|
| 2006 |
Gatbonton T, Imbesi M, Nelson M, Akey JM, Ruderfer DM, Kruglyak L, Simon JA, Bedalov A. Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. Plos Genetics. 2: e35. PMID 16552446 DOI: 10.1371/Journal.Pgen.0020035 |
0.648 |
|
| 2006 |
Mackelprang R, Livingston RJ, Eberle MA, Carlson CS, Yi Q, Akey JM, Nickerson DA. Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locus. Human Genetics. 119: 255-66. PMID 16425038 DOI: 10.1007/S00439-005-0111-Z |
0.315 |
|
| 2006 |
Gatbonton T, Imbesi M, Nelson M, Akey JM, Ruderfer DM, Kruglyak L, Simon JA, Bedalov A. Correction: Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast Plos Genetics. 2: e104. DOI: 10.1371/Journal.Pgen.0020104 |
0.681 |
|
| 2005 |
Reed FA, Akey JM, Aquadro CF. Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes. Genome Research. 15: 1211-21. PMID 16140989 DOI: 10.1101/gr.3413205 |
0.719 |
|
| 2005 |
Storey JD, Akey JM, Kruglyak L. Multiple locus linkage analysis of genomewide expression in yeast. Plos Biology. 3: e267. PMID 16035920 DOI: 10.1371/Journal.Pbio.0030267 |
0.664 |
|
| 2005 |
Ronald J, Akey JM. Genome-wide scans for loci under selection in humans. Human Genomics. 2: 113-25. PMID 16004726 DOI: 10.1186/1479-7364-2-2-113 |
0.503 |
|
| 2005 |
Shriver MD, Mei R, Parra EJ, Sonpar V, Halder I, Tishkoff SA, Schurr TG, Zhadanov SI, Osipova LP, Brutsaert TD, Friedlaender J, Jorde LB, Watkins WS, Bamshad MJ, Gutierrez G, ... ... Akey JM, et al. Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Human Genomics. 2: 81-9. PMID 16004724 DOI: 10.1186/1479-7364-2-2-81 |
0.378 |
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| 2005 |
Ronald J, Akey JM, Whittle J, Smith EN, Yvert G, Kruglyak L. Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays. Genome Research. 15: 284-91. PMID 15687292 DOI: 10.1101/Gr.2850605 |
0.792 |
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| 2004 |
Shriver MD, Kennedy GC, Parra EJ, Lawson HA, Sonpar V, Huang J, Akey JM, Jones KW. The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Human Genomics. 1: 274-86. PMID 15588487 DOI: 10.1186/1479-7364-1-4-274 |
0.332 |
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| 2004 |
Akey JM, Eberle MA, Rieder MJ, Carlson CS, Shriver MD, Nickerson DA, Kruglyak L. Population history and natural selection shape patterns of genetic variation in 132 genes. Plos Biology. 2: e286. PMID 15361935 DOI: 10.1371/Journal.Pbio.0020286 |
0.686 |
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| 2003 |
Yvert G, Brem RB, Whittle J, Akey JM, Foss E, Smith EN, Mackelprang R, Kruglyak L. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors. Nature Genetics. 35: 57-64. PMID 12897782 DOI: 10.1038/Ng1222 |
0.794 |
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| 2003 |
Zhang K, Akey JM, Wang N, Xiong M, Chakraborty R, Jin L. Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: an act of genetic drift. Human Genetics. 113: 51-9. PMID 12677424 DOI: 10.1007/S00439-003-0941-5 |
0.382 |
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| 2003 |
Akey JM, Zhang K, Xiong M, Jin L. The effect of single nucleotide polymorphism identification strategies on estimates of linkage disequilibrium. Molecular Biology and Evolution. 20: 232-42. PMID 12598690 DOI: 10.1093/Molbev/Msg032 |
0.413 |
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| 2003 |
Sun G, McGarvey ST, Bayoumi R, Mulligan CJ, Barrantes R, Raskin S, Zhong Y, Akey J, Chakraborty R, Deka R. Global genetic variation at nine short tandem repeat loci and implications on forensic genetics. European Journal of Human Genetics : Ejhg. 11: 39-49. PMID 12529704 DOI: 10.1038/Sj.Ejhg.5200902 |
0.478 |
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| 2002 |
Akey JM, Zhang G, Zhang K, Jin L, Shriver MD. Interrogating a high-density SNP map for signatures of natural selection. Genome Research. 12: 1805-14. PMID 12466284 DOI: 10.1101/gr.631202 |
0.509 |
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| 2002 |
Wang N, Akey JM, Zhang K, Chakraborty R, Jin L. Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. American Journal of Human Genetics. 71: 1227-34. PMID 12384857 DOI: 10.1086/344398 |
0.337 |
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| 2001 |
Akey JM, Wang H, Xiong M, Wu H, Liu W, Shriver MD, Jin L. Interaction between the melanocortin-1 receptor and P genes contributes to inter-individual variation in skin pigmentation phenotypes in a Tibetan population. Human Genetics. 108: 516-20. PMID 11499678 DOI: 10.1007/S004390100524 |
0.308 |
|
| 2001 |
Akey J, Jin L, Xiong M. Haplotypes vs single marker linkage disequilibrium tests: what do we gain? European Journal of Human Genetics : Ejhg. 9: 291-300. PMID 11313774 DOI: 10.1038/Sj.Ejhg.5200619 |
0.422 |
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| 2001 |
Akey JM, Sosnoski D, Parra E, Dios S, Hiester K, Su B, Bonilla C, Jin L, Shriver MD. Melting curve analysis of SNPs (McSNP): a gel-free and inexpensive approach for SNP genotyping. Biotechniques. 30: 358-62, 364, 366-7. PMID 11233605 DOI: 10.2144/01302Tt05 |
0.335 |
|
| 2000 |
Xiong M, Akey J, Jin L. The haplotype linkage disequilibrium test for genome-wide screens: its power and study design. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 675-86. PMID 10902215 |
0.326 |
|
| 1999 |
Su B, Xiao J, Underhill P, Deka R, Zhang W, Akey J, Huang W, Shen D, Lu D, Luo J, Chu J, Tan J, Shen P, Davis R, Cavalli-Sforza L, et al. Y-Chromosome evidence for a northward migration of modern humans into Eastern Asia during the last Ice Age. American Journal of Human Genetics. 65: 1718-24. PMID 10577926 DOI: 10.1086/302680 |
0.337 |
|
| 1998 |
Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, Forrester T, Allison DB, Deka R, Ferrell RE, Shriver MD. Estimating African American admixture proportions by use of population-specific alleles. American Journal of Human Genetics. 63: 1839-51. PMID 9837836 DOI: 10.1086/302148 |
0.424 |
|
| 1997 |
Shriver MD, Smith MW, Jin L, Marcini A, Akey JM, Deka R, Ferrell RE. Ethnic-affiliation estimation by use of population-specific DNA markers. American Journal of Human Genetics. 60: 957-64. PMID 9106543 |
0.301 |
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| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Tucci S, Akey JM. Population genetics: A map of human wanderlust. Nature. PMID 27654916 DOI: 10.1038/nature19472 |
0.298 |
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| 2001 |
Jiang Z, Akey JM, Shi J, Xiong M, Wang Y, Shen Y, Xu X, Chen H, Wu H, Xiao J, Lu D, Huang W, Jin L. A polymorphism in the promoter region of catalase is associated with blood pressure levels. Human Genetics. 109: 95-8. PMID 11479740 DOI: 10.1007/S004390100553 |
0.285 |
|
| 2012 |
Akey JM. Understanding human evolutionary history: a meeting report of the Swedish Royal Academy of Sciences symposium of modern human genetic variation. Investigative Genetics. 3: 7. PMID 22444404 DOI: 10.1186/2041-2223-3-7 |
0.281 |
|
| 2019 |
Tucci S, Akey JM. The long walk to African genomics. Genome Biology. 20: 130. PMID 31248437 DOI: 10.1186/s13059-019-1740-1 |
0.276 |
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| 2016 |
Searle BC, Gittelman RM, Manor O, Akey JM. Detecting Sources of Transcriptional Heterogeneity in Large-Scale RNA-Seq Data Sets. Genetics. PMID 27729424 DOI: 10.1534/genetics.116.193714 |
0.276 |
|
| 2010 |
Emery LS, Felsenstein J, Akey JM. Estimators of the human effective sex ratio detect sex biases on different timescales. American Journal of Human Genetics. 87: 848-56. PMID 21109223 DOI: 10.1016/j.ajhg.2010.10.021 |
0.269 |
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| 2012 |
O'Roak BJ, Vives L, Fu W, Egertson JD, Stanaway IB, Phelps IG, Carvill G, Kumar A, Lee C, Ankenman K, Munson J, Hiatt JB, Turner EH, Levy R, O'Day DR, ... ... Akey JM, et al. Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science (New York, N.Y.). 338: 1619-22. PMID 23160955 DOI: 10.1126/Science.1227764 |
0.259 |
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| 2013 |
Fu W, O’Connor TD, Jun G, Kang HM, Abecasis G, Leal SM, Gabriel S, Rieder MJ, Altshuler D, Shendure J, Nickerson DA, Bamshad MJ, Project NES, Akey JM. Erratum: Corrigendum: Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants Nature. 495: 270-270. DOI: 10.1038/Nature12022 |
0.259 |
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| 2012 |
Mathias RA, Fu W, Akey JM, Ainsworth HC, Torgerson DG, Ruczinski I, Sergeant S, Barnes KC, Chilton FH. Adaptive evolution of the FADS gene cluster within Africa. Plos One. 7: e44926. PMID 23028684 DOI: 10.1371/Journal.Pone.0044926 |
0.25 |
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| 2011 |
Akey J. Abstracts of Beyond the Genome 2011. Washington, DC, USA. September 19-22, 2011. Genome Biology. I1-18, P1-48. PMID 22607170 DOI: 10.1186/gb-2011-12-s1-i1 |
0.248 |
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| 2006 |
Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Current Biology : Cb. 16: 95-100. PMID 16401428 DOI: 10.1016/J.Cub.2005.11.045 |
0.244 |
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| 2012 |
O'Roak BJ, Vives L, Girirajan S, Karakoc E, Krumm N, Coe BP, Levy R, Ko A, Lee C, Smith JD, Turner EH, Stanaway IB, Vernot B, Malig M, Baker C, ... ... Akey JM, et al. Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations. Nature. 485: 246-50. PMID 22495309 DOI: 10.1038/Nature10989 |
0.241 |
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| 2012 |
Akey JM. Parallel selection: evolution's surprising predictability. Current Biology : Cb. 22: R407-9. PMID 22625859 DOI: 10.1016/j.cub.2012.04.014 |
0.228 |
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| 2007 |
Gojobori J, Tang H, Akey JM, Wu CI. Adaptive evolution in humans revealed by the negative correlation between the polymorphism and fixation phases of evolution. Proceedings of the National Academy of Sciences of the United States of America. 104: 3907-12. PMID 17360451 DOI: 10.1073/pnas.0605565104 |
0.225 |
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| 2016 |
McCoy RC, Akey JM. Patterns of deleterious variation between human populations reveal an unbalanced load. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787891 DOI: 10.1073/pnas.1524016113 |
0.221 |
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| 2022 |
Creevy KE, Akey JM, Kaeberlein M, Promislow DEL. An open science study of ageing in companion dogs. Nature. 602: 51-57. PMID 35110758 DOI: 10.1038/s41586-021-04282-9 |
0.219 |
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| 2022 |
Saha S, Khan N, Comi T, Verhagen A, Sasmal A, Diaz S, Yu H, Chen X, Akey JM, Frank M, Gagneux P, Varki A. Evolution of Human-specific Alleles Protecting Cognitive Function of Grandmothers. Molecular Biology and Evolution. PMID 35809046 DOI: 10.1093/molbev/msac151 |
0.212 |
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| 2001 |
Wu H, Wang H, Li H, Akey J, Xiao F, Ke Y, Xu H, Xiao J, Lu D, Parra E, Shriver M, Xiong M, Barton SA, Hewett-Emmett D, Liu W, et al. Skin reflectance in the Han Chinese and Tibetan populations Human Biology. 73: 461-466. PMID 11459426 DOI: 10.1353/Hub.2001.0043 |
0.21 |
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| 2003 |
Maksymowych WP, Reeve JP, Reveille JD, Akey JM, Buenviaje H, O'Brien L, Peloso PM, Thomson GT, Jin L, Russell AS. High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry. Arthritis and Rheumatism. 48: 2011-8. PMID 12847695 DOI: 10.1002/art.11037 |
0.203 |
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| 2004 |
Jin L, Zhang G, Akey JM, Luo J, Lee J, Weisman MH, Bruckel J, Inman RD, Stone MA, Khan MA, Schumacher HR, Maksymowych WP, Mahowald ML, Sawitzke AD, Vasey FB, et al. Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility. Arthritis and Rheumatism. 50: 3047-8. PMID 15457475 DOI: 10.1002/Art.20475 |
0.186 |
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| 2002 |
Akey DT, Akey JM, Zhang K, Jin L. Assaying DNA methylation based on high-throughput melting curve approaches. Genomics. 80: 376-84. PMID 12376091 DOI: 10.1006/geno.2002.6851 |
0.157 |
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| 2015 |
Shendure J, Akey JM. The origins, determinants, and consequences of human mutations. Science (New York, N.Y.). 349: 1478-83. PMID 26404824 DOI: 10.1126/Science.Aaa9119 |
0.156 |
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| 2016 |
Chaudhary A, Leite M, Kulasekara BR, Altura MA, Ogahara C, Weiss E, Fu W, Blanc MP, O'Keeffe M, Terhorst C, Akey JM, Miller SI. Human Diversity in a Cell Surface Receptor that Inhibits Autophagy. Current Biology : Cb. PMID 27345162 DOI: 10.1016/J.Cub.2016.05.003 |
0.154 |
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| 2013 |
Stergachis AB, Neph S, Reynolds A, Humbert R, Miller B, Paige SL, Vernot B, Cheng JB, Thurman RE, Sandstrom R, Haugen E, Heimfeld S, Murry CE, Akey JM, Stamatoyannopoulos JA. Developmental fate and cellular maturity encoded in human regulatory DNA landscapes. Cell. 154: 888-903. PMID 23953118 DOI: 10.1016/J.Cell.2013.07.020 |
0.152 |
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| 2001 |
Akey JM, Zhang K, Xiong M, Doris P, Jin L. The effect that genotyping errors have on the robustness of common linkage-disequilibrium measures. American Journal of Human Genetics. 68: 1447-56. PMID 11359212 DOI: 10.1086/320607 |
0.151 |
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| 2008 |
Mealey KL, Jabbes M, Spencer E, Akey JM. Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 38: 1305-12. PMID 18841518 DOI: 10.1080/00498250802446146 |
0.087 |
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| 2009 |
Yatsenko AS, Kucherenko MM, Pantoja M, Fischer KA, Madeoy J, Deng WM, Schneider M, Baumgartner S, Akey J, Shcherbata HR, Ruohola-Baker H. The conserved WW-domain binding sites in Dystroglycan C-terminus are essential but partially redundant for Dystroglycan function. Bmc Developmental Biology. 9: 18. PMID 19250553 DOI: 10.1186/1471-213X-9-18 |
0.079 |
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| 2020 |
Saad-Roy CM, Arinaminpathy N, Wingreen NS, Levin SA, Akey JM, Grenfell BT. Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans. Plos Computational Biology. 16: e1007892. PMID 32584807 DOI: 10.1371/Journal.Pcbi.1007892 |
0.078 |
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| 2014 |
Akey JE, Rintamaki LS. Optimal social support practices for health care professionals who treat patients managing eating disorders. The Journal of Nervous and Mental Disease. 202: 126-32. PMID 24469524 DOI: 10.1097/Nmd.0000000000000081 |
0.04 |
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| 2022 |
Creevy KE, Akey JM, Kaeberlein M, Promislow DEL. Author Correction: An open science study of ageing in companion dogs. Nature. PMID 35941194 DOI: 10.1038/s41586-022-05179-x |
0.04 |
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| 2013 |
Anker AE, Akey JE, Feeley TH. Providing social support in a persuasive context: forms of social support reported by organ procurement coordinators. Health Communication. 28: 835-45. PMID 23448519 DOI: 10.1080/10410236.2012.728468 |
0.033 |
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| 2013 |
Akey JE, Rintamaki LS, Kane TL. Health Belief Model deterrents of social support seeking among people coping with eating disorders. Journal of Affective Disorders. 145: 246-52. PMID 22840616 DOI: 10.1016/J.Jad.2012.04.045 |
0.026 |
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| Hide low-probability matches. |