Sarkis K. Mazmanian, Ph.D. - Publications

Affiliations: 
2002 University of California, Los Angeles, Los Angeles, CA 
Area:
Microbiology Biology, Cell Biology

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Bostick JW, Schonhoff AM, Mazmanian SK. Gut microbiome-mediated regulation of neuroinflammation. Current Opinion in Immunology. 76: 102177. PMID 35462279 DOI: 10.1016/j.coi.2022.102177  0.307
2020 Morais LH, Schreiber HL, Mazmanian SK. The gut microbiota-brain axis in behaviour and brain disorders. Nature Reviews. Microbiology. PMID 33093662 DOI: 10.1038/s41579-020-00460-0  0.31
2020 Donaldson GP, Chou WC, Manson AL, Rogov P, Abeel T, Bochicchio J, Ciulla D, Melnikov A, Ernst PB, Chu H, Giannoukos G, Earl AM, Mazmanian SK. Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice. Nature Microbiology. PMID 32152589 DOI: 10.1038/S41564-020-0683-3  0.414
2020 Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, ... ... Mazmanian SK, et al. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. PMID 32103176 DOI: 10.1038/S41586-020-2047-9  0.328
2020 Sampson TR, Challis C, Jain N, Moiseyenko A, Ladinsky MS, Shastri GG, Thron T, Needham BD, Horvath I, Debelius JW, Janssen S, Knight R, Wittung-Stafshede P, Gradinaru V, Chapman M, ... Mazmanian SK, et al. A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice. Elife. 9. PMID 32043464 DOI: 10.7554/Elife.53111  0.347
2019 Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, ... ... Mazmanian SK, et al. Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. Cell. 177: 1600-1618.e17. PMID 31150625 DOI: 10.1016/J.Cell.2019.05.004  0.365
2019 Pizarro TT, Stappenbeck TS, Rieder F, Rosen MJ, Colombel JF, Donowitz M, Towne J, Mazmanian SK, Faith JJ, Hodin RA, Garrett WS, Fichera A, Poritz LS, Cortes CJ, Shtraizent N, et al. Challenges in IBD Research: Preclinical Human IBD Mechanisms. Inflammatory Bowel Diseases. 25: S5-S12. PMID 31095706 DOI: 10.1093/Ibd/Izz075  0.306
2019 Ramakrishna C, Kujawski M, Chu H, Li L, Mazmanian SK, Cantin EM. Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis. Nature Communications. 10: 2153. PMID 31089128 DOI: 10.1038/S41467-019-09884-6  0.375
2018 Griffiths JA, Mazmanian SK. Emerging evidence linking the gut microbiome to neurologic disorders. Genome Medicine. 10: 98. PMID 30577867 DOI: 10.1186/S13073-018-0609-3  0.403
2018 Abdel-Haq R, Schlachetzki JCM, Glass CK, Mazmanian SK. Microbiome-microglia connections via the gut-brain axis. The Journal of Experimental Medicine. PMID 30385457 DOI: 10.1084/Jem.20180794  0.371
2018 Schretter CE, Vielmetter J, Bartos I, Marka Z, Marka S, Argade S, Mazmanian SK. A gut microbial factor modulates locomotor behaviour in Drosophila. Nature. PMID 30356215 DOI: 10.1038/S41586-018-0634-9  0.391
2018 Donaldson GP, Ladinsky MS, Yu KB, Sanders JG, Yoo BB, Chou WC, Conner ME, Earl AM, Knight R, Bjorkman PJ, Mazmanian SK. Gut microbiota utilize immunoglobulin A for mucosal colonization. Science (New York, N.Y.). PMID 29724905 DOI: 10.1126/Science.Aaq0926  0.493
2018 Schretter CE, Mazmanian SK. Cultivating a Relationship with Gut Bacteria. Cell Metabolism. 27: 267-268. PMID 29414679 DOI: 10.1016/J.Cmet.2018.01.010  0.361
2018 Bacquie V, Olier M, Robbe-Masselot C, Ellero-Simatos S, Inczefi O, Sharon G, Bétoulières C, Theodorou V, Mazmanian S, Turner J, Mercier-Bonin M, Ferrier L. 136 - Impact of Epithelial Barrier Disruption on Mucus Layer and GUT Microbiota in Mice Gastroenterology. 154: S-37. DOI: 10.1016/S0016-5085(18)30594-8  0.332
2017 Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Katz Sand I, Gacias M, Zhu Y, Casaccia P, ... ... Mazmanian SK, et al. Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 28893978 DOI: 10.1073/Pnas.1711235114  0.36
2017 Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR. The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability. Cellular and Molecular Gastroenterology and Hepatology. 4: 285-297. PMID 28795125 DOI: 10.1016/J.Jcmgh.2017.06.001  0.411
2017 Yoo BB, Mazmanian SK. The Enteric Network: Interactions between the Immune and Nervous Systems of the Gut. Immunity. 46: 910-926. PMID 28636959 DOI: 10.1016/J.Immuni.2017.05.011  0.428
2017 Kollmann TR, Kampmann B, Mazmanian SK, Marchant A, Levy O. Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny. Immunity. 46: 350-363. PMID 28329702 DOI: 10.1016/J.Immuni.2017.03.009  0.368
2016 Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, ... ... Mazmanian SK, et al. Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease. Cell. 167: 1469-1480.e12. PMID 27912057 DOI: 10.1016/J.Cell.2016.11.018  0.387
2016 Sharon G, Sampson TR, Geschwind DH, Mazmanian SK. The Central Nervous System and the Gut Microbiome. Cell. 167: 915-932. PMID 27814521 DOI: 10.1016/J.Cell.2016.10.027  0.348
2016 Neff CP, Rhodes ME, Arnolds KL, Collins CB, Donnelly J, Nusbacher N, Jedlicka P, Schneider JM, McCarter MD, Shaffer M, Mazmanian SK, Palmer BE, Lozupone CA. Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties. Cell Host & Microbe. PMID 27693306 DOI: 10.1016/J.Chom.2016.09.002  0.44
2016 Meisel M, Mayassi T, Fehlner-Peach H, Koval JC, O'Brien SL, Hinterleitner R, Lesko K, Kim S, Bouziat R, Chen L, Weber CR, Mazmanian SK, Jabri B, Antonopoulos DA. Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis. The Isme Journal. PMID 27648810 DOI: 10.1038/Ismej.2016.114  0.372
2016 Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, ... ... Mazmanian SK, et al. Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease. Science (New York, N.Y.). 352: 1116-20. PMID 27230380 DOI: 10.1126/Science.Aad9948  0.415
2015 Donaldson GP, Lee SM, Mazmanian SK. Gut biogeography of the bacterial microbiota. Nature Reviews. Microbiology. PMID 26499895 DOI: 10.1038/Nrmicro3552  0.439
2015 Chu H, Mazmanian SK. Winning the Microbial Battle, but Not the War. Cell. 163: 271-2. PMID 26451475 DOI: 10.1016/J.Cell.2015.09.050  0.381
2015 Sampson TR, Mazmanian SK. Control of brain development, function, and behavior by the microbiome. Cell Host & Microbe. 17: 565-76. PMID 25974299 DOI: 10.1016/J.Chom.2015.04.011  0.397
2015 Yano JM, Yu K, Donaldson GP, Shastri GG, Ann P, Ma L, Nagler CR, Ismagilov RF, Mazmanian SK, Hsiao EY. Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell. 161: 264-76. PMID 25860609 DOI: 10.1016/J.Cell.2015.02.047  0.318
2014 Sharon G, Garg N, Debelius J, Knight R, Dorrestein PC, Mazmanian SK. Specialized metabolites from the microbiome in health and disease. Cell Metabolism. 20: 719-30. PMID 25440054 DOI: 10.1016/J.Cmet.2014.10.016  0.436
2014 Mayer EA, Knight R, Mazmanian SK, Cryan JF, Tillisch K. Gut microbes and the brain: paradigm shift in neuroscience. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15490-6. PMID 25392516 DOI: 10.1523/Jneurosci.3299-14.2014  0.34
2014 Stefka AT, Feehley T, Tripathi P, Qiu J, McCoy K, Mazmanian SK, Tjota MY, Seo GY, Cao S, Theriault BR, Antonopoulos DA, Zhou L, Chang EB, Fu YX, Nagler CR. Commensal bacteria protect against food allergen sensitization. Proceedings of the National Academy of Sciences of the United States of America. 111: 13145-50. PMID 25157157 DOI: 10.1073/Pnas.1412008111  0.372
2014 Dorrestein PC, Mazmanian SK, Knight R. Finding the missing links among metabolites, microbes, and the host. Immunity. 40: 824-32. PMID 24950202 DOI: 10.1016/J.Immuni.2014.05.015  0.406
2014 Lee YK, Mazmanian SK. Microbial learning lessons: SFB educate the immune system. Immunity. 40: 457-9. PMID 24745329 DOI: 10.1016/J.Immuni.2014.04.002  0.368
2014 Khosravi A, Yáñez A, Price JG, Chow A, Merad M, Goodridge HS, Mazmanian SK. Gut microbiota promote hematopoiesis to control bacterial infection. Cell Host & Microbe. 15: 374-81. PMID 24629343 DOI: 10.1016/J.Chom.2014.02.006  0.486
2014 Mahdavi A, Szychowski J, Ngo JT, Sweredoski MJ, Graham RL, Hess S, Schneewind O, Mazmanian SK, Tirrell DA. Identification of secreted bacterial proteins by noncanonical amino acid tagging. Proceedings of the National Academy of Sciences of the United States of America. 111: 433-8. PMID 24347637 DOI: 10.1073/Pnas.1301740111  0.392
2014 Mazmanian SK, Lee YK. Interplay between Intestinal Microbiota and Host Immune System Journal of Bacteriology and Virology. 44: 1-9. DOI: 10.4167/Jbv.2014.44.1.1  0.478
2013 Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral and physiological abnormalities associated with neurodevelopmental disorders. Cell. 155: 1451-63. PMID 24315484 DOI: 10.1016/J.Cell.2013.11.024  0.368
2013 Lee SM, Donaldson GP, Mikulski Z, Boyajian S, Ley K, Mazmanian SK. Bacterial colonization factors control specificity and stability of the gut microbiota. Nature. 501: 426-9. PMID 23955152 DOI: 10.1038/Nature12447  0.442
2013 Chu H, Mazmanian SK. Innate immune recognition of the microbiota promotes host-microbial symbiosis. Nature Immunology. 14: 668-75. PMID 23778794 DOI: 10.1038/Ni.2635  0.475
2013 Khosravi A, Mazmanian SK. Disruption of the gut microbiome as a risk factor for microbial infections. Current Opinion in Microbiology. 16: 221-7. PMID 23597788 DOI: 10.1016/J.Mib.2013.03.009  0.455
2013 McFall-Ngai M, Hadfield MG, Bosch TC, Carey HV, Domazet-LoÅ¡o T, Douglas AE, Dubilier N, Eberl G, Fukami T, Gilbert SF, Hentschel U, King N, Kjelleberg S, Knoll AH, Kremer N, ... Mazmanian SK, et al. Animals in a bacterial world, a new imperative for the life sciences. Proceedings of the National Academy of Sciences of the United States of America. 110: 3229-36. PMID 23391737 DOI: 10.1073/Pnas.1218525110  0.347
2013 Noval Rivas M, Burton OT, Wise P, Zhang YQ, Hobson SA, Garcia Lloret M, Chehoud C, Kuczynski J, DeSantis T, Warrington J, Hyde ER, Petrosino JF, Gerber GK, Bry L, Oettgen HC, ... Mazmanian SK, et al. A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis. The Journal of Allergy and Clinical Immunology. 131: 201-12. PMID 23201093 DOI: 10.1016/J.Jaci.2012.10.026  0.376
2012 Shen Y, Giardino Torchia ML, Lawson GW, Karp CL, Ashwell JD, Mazmanian SK. Outer membrane vesicles of a human commensal mediate immune regulation and disease protection. Cell Host & Microbe. 12: 509-20. PMID 22999859 DOI: 10.1016/J.Chom.2012.08.004  0.441
2012 Hsiao EY, McBride SW, Chow J, Mazmanian SK, Patterson PH. Modeling an autism risk factor in mice leads to permanent immune dysregulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 12776-81. PMID 22802640 DOI: 10.1073/Pnas.1202556109  0.392
2012 Wingender G, Stepniak D, Krebs P, Lin L, McBride S, Wei B, Braun J, Mazmanian SK, Kronenberg M. Intestinal microbes affect phenotypes and functions of invariant natural killer T cells in mice. Gastroenterology. 143: 418-28. PMID 22522092 DOI: 10.1053/J.Gastro.2012.04.017  0.363
2012 Khosravi A, Mazmanian SK. Breathe easy: microbes protect from allergies. Nature Medicine. 18: 492-4. PMID 22481405 DOI: 10.1038/Nm.2723  0.383
2012 Hsiao E, McBride S, Chow J, Mazmanian S, Patterson P. 119. Modeling an autism risk factor in mice leads to permanent changes in the immune system Brain, Behavior, and Immunity. 26: S33. DOI: 10.1016/J.Bbi.2012.07.143  0.406
2011 Chow J, Tang H, Mazmanian SK. Pathobionts of the gastrointestinal microbiota and inflammatory disease. Current Opinion in Immunology. 23: 473-80. PMID 21856139 DOI: 10.1016/J.Coi.2011.07.010  0.465
2011 Huang JY, Lee SM, Mazmanian SK. The human commensal Bacteroides fragilis binds intestinal mucin. Anaerobe. 17: 137-41. PMID 21664470 DOI: 10.1016/J.Anaerobe.2011.05.017  0.393
2011 Round JL, Lee SM, Li J, Tran G, Jabri B, Chatila TA, Mazmanian SK. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science (New York, N.Y.). 332: 974-7. PMID 21512004 DOI: 10.1126/Science.1206095  0.472
2011 Lee YK, Menezes JS, Umesaki Y, Mazmanian SK. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 108: 4615-22. PMID 20660719 DOI: 10.1073/Pnas.1000082107  0.445
2010 Lee YK, Mazmanian SK. Has the microbiota played a critical role in the evolution of the adaptive immune system? Science (New York, N.Y.). 330: 1768-73. PMID 21205662 DOI: 10.1126/Science.1195568  0.478
2010 Chow J, Lee SM, Shen Y, Khosravi A, Mazmanian SK. Host-bacterial symbiosis in health and disease. Advances in Immunology. 107: 243-74. PMID 21034976 DOI: 10.1016/B978-0-12-381300-8.00008-3  0.503
2010 Round JL, Mazmanian SK. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proceedings of the National Academy of Sciences of the United States of America. 107: 12204-9. PMID 20566854 DOI: 10.1073/Pnas.0909122107  0.461
2010 Chow J, Mazmanian SK. A pathobiont of the microbiota balances host colonization and intestinal inflammation. Cell Host & Microbe. 7: 265-76. PMID 20413095 DOI: 10.1016/J.Chom.2010.03.004  0.465
2010 Round JL, O'Connell RM, Mazmanian SK. Coordination of tolerogenic immune responses by the commensal microbiota. Journal of Autoimmunity. 34: J220-5. PMID 19963349 DOI: 10.1016/J.Jaut.2009.11.007  0.477
2009 Mazmanian SK. Gut immune balance is as easy as S-F-B. Immunity. 31: 536-8. PMID 19833084 DOI: 10.1016/J.Immuni.2009.09.005  0.401
2009 Round JL, Mazmanian SK. The gut microbiota shapes intestinal immune responses during health and disease. Nature Reviews. Immunology. 9: 313-23. PMID 19343057 DOI: 10.1038/Nri2515  0.487
2009 Chow J, Mazmanian SK. Getting the bugs out of the immune system: do bacterial microbiota "fix" intestinal T cell responses? Cell Host & Microbe. 5: 8-12. PMID 19154983 DOI: 10.1016/J.Chom.2008.12.006  0.463
2009 Round JL, Mazmanian SK. Erratum: The gut microbiota shapes intestinal immune responses during health and disease (Nature Reviews Immunology (2009) 9 (313-323)) Nature Reviews Immunology. 9. DOI: 10.1038/Nri2614  0.421
2008 Mazmanian SK, Round JL, Kasper DL. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature. 453: 620-5. PMID 18509436 DOI: 10.1038/Nature07008  0.466
2008 Mazmanian SK. Capsular polysaccharides of symbiotic bacteria modulate immune responses during experimental colitis. Journal of Pediatric Gastroenterology and Nutrition. 46: E11-2. PMID 18354314 DOI: 10.1097/01.Mpg.0000313824.70971.A7  0.398
2008 Liu CH, Lee SM, Vanlare JM, Kasper DL, Mazmanian SK. Regulation of surface architecture by symbiotic bacteria mediates host colonization. Proceedings of the National Academy of Sciences of the United States of America. 105: 3951-6. PMID 18319345 DOI: 10.1073/Pnas.0709266105  0.427
2007 Garrett WS, Lord GM, Punit S, Lugo-Villarino G, Mazmanian SK, Ito S, Glickman JN, Glimcher LH. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell. 131: 33-45. PMID 17923086 DOI: 10.1016/J.Cell.2007.08.017  0.356
2006 Mazmanian SK, Kasper DL. The love-hate relationship between bacterial polysaccharides and the host immune system. Nature Reviews. Immunology. 6: 849-58. PMID 17024229 DOI: 10.1038/Nri1956  0.438
2005 Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell. 122: 107-18. PMID 16009137 DOI: 10.1016/J.Cell.2005.05.007  0.482
2004 Zhang R, Wu R, Joachimiak G, Mazmanian SK, Missiakas DM, Gornicki P, Schneewind O, Joachimiak A. Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site. Structure (London, England : 1993). 12: 1147-56. PMID 15242591 DOI: 10.1016/J.Str.2004.06.001  0.308
2004 Zong Y, Mazmanian SK, Schneewind O, Narayana SV. The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall. Structure (London, England : 1993). 12: 105-12. PMID 14725770 DOI: 10.1016/J.Str.2003.11.021  0.334
2003 Jonsson IM, Mazmanian SK, Schneewind O, Bremell T, Tarkowski A. The role of Staphylococcus aureus sortase A and sortase B in murine arthritis. Microbes and Infection / Institut Pasteur. 5: 775-80. PMID 12850203 DOI: 10.1016/S1286-4579(03)00143-6  0.343
2002 Jonsson IM, Mazmanian SK, Schneewind O, Verdrengh M, Bremell T, Tarkowski A. On the role of Staphylococcus aureus sortase and sortase-catalyzed surface protein anchoring in murine septic arthritis. The Journal of Infectious Diseases. 185: 1417-24. PMID 11992276 DOI: 10.1086/340503  0.329
2002 Bierne H, Mazmanian SK, Trost M, Pucciarelli MG, Liu G, Dehoux P, Jänsch L, Garcia-del Portillo F, Schneewind O, Cossart P. Inactivation of the srtA gene in Listeria monocytogenes inhibits anchoring of surface proteins and affects virulence. Molecular Microbiology. 43: 869-81. PMID 11929538 DOI: 10.1046/J.1365-2958.2002.02798.X  0.381
2002 Mazmanian SK, Ton-That H, Su K, Schneewind O. An iron-regulated sortase anchors a class of surface protein during Staphylococcus aureus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 2293-8. PMID 11830639 DOI: 10.1073/Pnas.032523999  0.33
2001 Mazmanian SK, Ton-That H, Schneewind O. Sortase-catalysed anchoring of surface proteins to the cell wall of Staphylococcus aureus. Molecular Microbiology. 40: 1049-57. PMID 11401711 DOI: 10.1046/J.1365-2958.2001.02411.X  0.328
2000 Mazmanian SK, Liu G, Jensen ER, Lenoy E, Schneewind O. Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections. Proceedings of the National Academy of Sciences of the United States of America. 97: 5510-5. PMID 10805806 DOI: 10.1073/Pnas.080520697  0.362
1999 Mazmanian SK, Liu G, Ton-That H, Schneewind O. Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall. Science (New York, N.Y.). 285: 760-3. PMID 10427003 DOI: 10.1126/Science.285.5428.760  0.347
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