Deepak Shukla - Publications

Affiliations: 
Microbiology and Immunology University of Illinois at Chicago, Chicago, IL, United States 
Area:
Microbiology Biology, Virology Biology

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gagan S, Khapuinamai A, Kapoor D, Sharma P, Yadavalli T, Joseph J, Shukla D, Bagga B. Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies. Investigative Ophthalmology & Visual Science. 65: 7. PMID 38466284 DOI: 10.1167/iovs.65.3.7  0.448
2024 Naqvi RA, Valverde A, Yadavalli T, Bobat FI, Capistrano KJ, Shukla D, Naqvi AR. Viral MicroRNAs in Herpes Simplex Virus 1 Pathobiology. Current Pharmaceutical Design. PMID 38347772 DOI: 10.2174/0113816128286469240129100313  0.331
2023 Bhattacharya I, Volety I, Shukla D. OPTN-TBK1 axis and a role for PLK1 in HSV-1 infection. Mbio. 14: e0271523. PMID 38019030 DOI: 10.1128/mbio.02715-23  0.563
2023 Yadavalli T, Patil C, Sharma P, Volety I, Borase H, Kapoor D, Shukla D. Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence. Investigative Ophthalmology & Visual Science. 64: 41. PMID 38015175 DOI: 10.1167/iovs.64.14.41  0.443
2023 Borase H, Shukla D. The Interplay of Genital Herpes with Cellular Processes: A Pathogenesis and Therapeutic Perspective. Viruses. 15. PMID 38005873 DOI: 10.3390/v15112195  0.394
2023 Sutar Y, Singh SK, Dhoble S, Mali J, Adams J, Yadavalli T, Date AA, Shukla D. Oral Self-Nanoemulsifying System Containing Ionic Liquid of BX795 Is Effective against Genital HSV-2 Infection in Mice. Acs Infectious Diseases. PMID 37807721 DOI: 10.1021/acsinfecdis.3c00212  0.329
2023 Chopra P, Yadavalli T, Palmieri F, Jongkees SAK, Unione L, Shukla D, Boons GJ. Synthetic Heparanase Inhibitors Can Prevent Herpes Simplex Viral Spread. Angewandte Chemie (International Ed. in English). e202309838. PMID 37555536 DOI: 10.1002/anie.202309838  0.568
2023 Yin XT, Hartman A, Sirajuddin N, Shukla D, Leger AS, Keadle TL, Stuart PM. UV-B induced HSV-1 reactivation leads to infectious virus in the corneas of virtually all latently infected mice and requires an intact STING to develop herpetic stromal keratitis. Research Square. PMID 37502845 DOI: 10.21203/rs.3.rs-3097720/v1  0.35
2023 Suryawanshi RK, Patil CD, Agelidis A, Koganti R, Yadavalli T, Ames JM, Borase H, Shukla D. Pathophysiology of reinfection by exogenous HSV-1 is driven by heparanase dysfunction. Science Advances. 9: eadf3977. PMID 37115924 DOI: 10.1126/sciadv.adf3977  0.54
2023 Kapoor D, Shukla D. Neutrophil Extracellular Traps and Their Possible Implications in Ocular Herpes Infection. Pathogens (Basel, Switzerland). 12. PMID 36839481 DOI: 10.3390/pathogens12020209  0.476
2023 Elste J, Chan A, Patil C, Tripathi V, Shadrack DM, Jaishankar D, Hawkey A, Mungerson MS, Shukla D, Tiwari V. Archaic connectivity between the sulfated heparan sulfate and the herpesviruses - An evolutionary potential for cross-species interactions. Computational and Structural Biotechnology Journal. 21: 1030-1040. PMID 36733705 DOI: 10.1016/j.csbj.2023.01.005  0.36
2022 Suryawanshi RK, Patil CD, Wu D, Panda PK, Singh SK, Volety I, Ahuja R, Mishra YK, Shukla D. Putative targeting by BX795 causes decrease in protein kinase C protein levels and inhibition of HSV1 infection. Antiviral Research. 208: 105454. PMID 36334637 DOI: 10.1016/j.antiviral.2022.105454  0.429
2022 Sharma P, Kapoor D, Shukla D. Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells. Viruses. 14. PMID 36298711 DOI: 10.3390/v14102156  0.581
2022 Patil CD, Suryawanshi RK, Kapoor D, Shukla D. Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication. Mbio. e0219422. PMID 36043789 DOI: 10.1128/mbio.02194-22  0.436
2022 Yadavalli T, Sharma P, Wu D, Kapoor D, Shukla D. CREB3 Plays an Important Role in HPSE-Facilitated HSV-1 Release in Human Corneal Epithelial Cells. Viruses. 14. PMID 35746643 DOI: 10.3390/v14061171  0.57
2022 Bhattacharya I, Yadavalli T, Wu D, Shukla D. Plasma Membrane-Derived Liposomes Exhibit Robust Antiviral Activity against HSV-1. Viruses. 14. PMID 35458528 DOI: 10.3390/v14040799  0.448
2022 Grinage E, Shukla D. Optineurin in ocular herpes infection. Experimental Eye Research. 219: 109059. PMID 35390332 DOI: 10.1016/j.exer.2022.109059  0.555
2022 Iqbal A, Suryawanshi R, Yadavalli T, Volety I, Shukla D. Erratum to "BX795 demonstrates potent antiviral benefits against herpes simplex Virus-1 infection of human cell lines" [Antivir. Res. 80 (2020) 104814]. Antiviral Research. 200: 105293. PMID 35337670 DOI: 10.1016/j.antiviral.2022.105293  0.558
2022 Patil CD, Shukla D. OPTN (optineurin)-mediated selective autophagy prevents neurodegeneration due to herpesvirus infection. Autophagy. 1-2. PMID 35167411 DOI: 10.1080/15548627.2022.2037223  0.464
2021 Patil CD, Suryawanshi R, Ames J, Koganti R, Agelidis A, Kapoor D, Yadavalli T, Koujah L, Tseng HC, Shukla D. Intrinsic Antiviral Activity of Optineurin Prevents Hyperproliferation of a Primary Herpes Simplex Virus Type 2 Infection. Journal of Immunology (Baltimore, Md. : 1950). 208: 63-73. PMID 34880107 DOI: 10.4049/jimmunol.2100472  0.59
2021 Koujah L, Madavaraju K, Agelidis AM, Patil CD, Shukla D. Heparanase-Induced Activation of AKT Stabilizes β-Catenin and Modulates Wnt/β-Catenin Signaling during Herpes Simplex Virus 1 Infection. Mbio. 12: e0279221. PMID 34749529 DOI: 10.1128/mBio.02792-21  0.342
2021 Yadavalli T, Volety I, Shukla D. Aptamers in Virology-A Consolidated Review of the Most Recent Advancements in Diagnosis and Therapy. Pharmaceutics. 13. PMID 34683938 DOI: 10.3390/pharmaceutics13101646  0.377
2021 Suryawanshi RK, Patil CD, Agelidis A, Koganti R, Ames JM, Koujah L, Yadavalli T, Madavaraju K, Shantz LM, Shukla D. mTORC2 confers neuroprotection and potentiates immunity during virus infection. Nature Communications. 12: 6020. PMID 34650053 DOI: 10.1038/s41467-021-26260-5  0.508
2021 Yadavalli T, Volety I, Shukla D. Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals. Journal of Visualized Experiments : Jove. PMID 34605808 DOI: 10.3791/62195  0.484
2021 Karasneh GA, Kapoor D, Bellamkonda N, Patil CD, Shukla D. Protease, Growth Factor, and Heparanase-Mediated Syndecan-1 Shedding Leads to Enhanced HSV-1 Egress. Viruses. 13. PMID 34578329 DOI: 10.3390/v13091748  0.82
2021 Naqvi AR, Schwartz J, Brandini DA, Schaller S, Hussein H, Valverde A, Naqvi RA, Shukla D. COVID-19 and oral diseases: Assessing manifestations of a new pathogen in oral infections. International Reviews of Immunology. 1-15. PMID 34525891 DOI: 10.1080/08830185.2021.1967949  0.343
2021 Ames J, Yadavalli T, Suryawanshi R, Hopkins J, Agelidis A, Patil C, Fredericks B, Tseng H, Valyi-Nagy T, Shukla D. OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection. Nature Communications. 12: 5401. PMID 34518549 DOI: 10.1038/s41467-021-25642-z  0.526
2021 Madavaraju K, Yadavalli T, Singh SK, Qatanani F, Shukla D. Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection. Antiviral Research. 105145. PMID 34303747 DOI: 10.1016/j.antiviral.2021.105145  0.506
2021 Suryawanshi RK, Patil CD, Koganti R, Singh SK, Ames JM, Shukla D. Heparan Sulfate Binding Cationic Peptides Restrict SARS-CoV-2 Entry. Pathogens (Basel, Switzerland). 10. PMID 34202835 DOI: 10.3390/pathogens10070803  0.307
2021 Tiwari V, Koganti R, Russell G, Sharma A, Shukla D. Role of Tunneling Nanotubes in Viral Infection, Neurodegenerative Disease, and Cancer. Frontiers in Immunology. 12: 680891. PMID 34194434 DOI: 10.3389/fimmu.2021.680891  0.479
2021 Koganti R, Memon A, Shukla D. Emerging Roles of Heparan Sulfate Proteoglycans in Viral Pathogenesis. Seminars in Thrombosis and Hemostasis. 47: 283-294. PMID 33851373 DOI: 10.1055/s-0041-1725068  0.585
2021 Koujah L, Allaham M, Patil CD, Ames JM, Suryawanshi RK, Yadavalli T, Agelidis A, Mun C, Surenkhuu B, Jain S, Shukla D. Entry receptor bias in evolutionarily distant HSV-1 clinical strains drives divergent ocular and nervous system pathologies. The Ocular Surface. PMID 33766740 DOI: 10.1016/j.jtos.2021.03.005  0.426
2021 Agelidis A, Turturice BA, Suryawanshi RK, Yadavalli T, Jaishankar D, Ames J, Hopkins J, Koujah L, Patil CD, Hadigal SR, Kyzar EJ, Campeau A, Wozniak JM, Gonzalez DJ, Vlodavsky I, ... ... Shukla D, et al. Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival. Jci Insight. PMID 33621216 DOI: 10.1172/jci.insight.144255  0.475
2021 Koganti R, Yadavalli T, Naqvi RA, Shukla D, Naqvi AR. Pathobiology and treatment of viral keratitis. Experimental Eye Research. 205: 108483. PMID 33556334 DOI: 10.1016/j.exer.2021.108483  0.381
2021 Yadavalli T, Koganti R, Shukla D. Infection-Induced Porcine Ex Vivo Corneal Wound Model to Study the Efficacy of Herpes Simplex Virus-1 Entry and Replication Inhibitors. Methods in Molecular Biology (Clifton, N.J.). 2193: 183-196. PMID 32808270 DOI: 10.1007/978-1-0716-0845-6_18  0.621
2020 Madavaraju K, Koganti R, Volety I, Yadavalli T, Shukla D. Herpes Simplex Virus Cell Entry Mechanisms: An Update. Frontiers in Cellular and Infection Microbiology. 10: 617578. PMID 33537244 DOI: 10.3389/fcimb.2020.617578  0.567
2020 Suryawanshi RK, Koganti R, Agelidis A, Patil CD, Shukla D. Dysregulation of Cell Signaling by SARS-CoV-2. Trends in Microbiology. PMID 33451855 DOI: 10.1016/j.tim.2020.12.007  0.402
2020 Yadavalli T, Suryawanshi R, Koganti R, Hopkins J, Ames J, Koujah L, Iqbal A, Madavaraju K, Agelidis A, Shukla D. Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing. Science Advances. 6. PMID 33277262 DOI: 10.1126/sciadv.abd9443  0.506
2020 Hopkins J, Yadavalli T, Suryawanshi R, Qatanani F, Volety I, Koganti R, Iqbal A, Shukla D. In Vitro and In Vivo Activity, Tolerability and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus-2 Genital Infection. Antimicrobial Agents and Chemotherapy. PMID 32601167 DOI: 10.1128/Aac.00245-20  0.585
2020 Wu D, Koganti R, Lambe UP, Yadavalli T, Nandi SS, Shukla D. Vaccines and Therapies in Development for SARS-CoV-2 Infections. Journal of Clinical Medicine. 9. PMID 32560227 DOI: 10.3390/Jcm9061885  0.349
2020 Koganti R, Suryawanshi R, Shukla D. Heparanase, cell signaling, and viral infections. Cellular and Molecular Life Sciences : Cmls. PMID 32462405 DOI: 10.1007/S00018-020-03559-Y  0.555
2020 Iqbal A, Suryawanshi R, Yadavalli T, Volety I, Shukla D. BX795 Demonstrates Potent Antiviral Benefits against Herpes Simplex Virus-1 Infection of Human Cell Lines. Antiviral Research. 104814. PMID 32380150 DOI: 10.1016/J.Antiviral.2020.104814  0.622
2020 Suryawanshi RK, Koujah L, Patil CD, Ames JM, Agelidis A, Yadavalli T, Patil SV, Shukla D. Bacterial pigment prodigiosin demonstrates a unique anti-herpesvirus activity that is mediated through inhibition of prosurvival signal transducers. Journal of Virology. PMID 32295926 DOI: 10.1128/Jvi.00251-20  0.627
2020 Agelidis A, Shukla D. Heparanase, Heparan Sulfate and Viral Infection. Advances in Experimental Medicine and Biology. 1221: 759-770. PMID 32274736 DOI: 10.1007/978-3-030-34521-1_32  0.669
2019 Hadigal S, Koganti R, Yadavalli T, Agelidis A, Suryawanshi R, Shukla D. Heparanase Regulated Syndecan-1 Shedding Facilitates HSV-1 Egress. Journal of Virology. PMID 31827001 DOI: 10.1128/Jvi.01672-19  0.614
2019 Yadavalli T, Suryawanshi R, Ali M, Iqbal A, Koganti R, Ames J, Aakalu VK, Shukla D. Prior inhibition of AKT phosphorylation by BX795 can define a safer strategy to prevent herpes simplex virus-1 infection of the eye. The Ocular Surface. PMID 31770600 DOI: 10.1016/J.Jtos.2019.11.011  0.529
2019 Koganti R, Yadavalli T, Shukla D. Current and Emerging Therapies for Ocular Herpes Simplex Virus Type-1 Infections. Microorganisms. 7. PMID 31658632 DOI: 10.3390/microorganisms7100429  0.517
2019 Yadavalli T, Ames J, Agelidis A, Suryawanshi R, Jaishankar D, Hopkins J, Thakkar N, Koujah L, Shukla D. Drug-encapsulated carbon (DECON): A novel platform for enhanced drug delivery. Science Advances. 5: eaax0780. PMID 31453334 DOI: 10.1126/Sciadv.Aax0780  0.394
2019 Koujah L, Shukla D, Naqvi AR. CRISPR-Cas Based Targeting of Host and Viral Genes as an Antiviral Strategy. Seminars in Cell & Developmental Biology. PMID 30953741 DOI: 10.1016/J.Semcdb.2019.04.004  0.505
2019 Agelidis A, Koujah L, Suryawanshi R, Yadavalli T, Mishra YK, Adelung R, Shukla D. An Intra-Vaginal Zinc Oxide Tetrapod Nanoparticles (ZOTEN) and Genital Herpesvirus Cocktail Can Provide a Novel Platform for Live Virus Vaccine. Frontiers in Immunology. 10: 500. PMID 30949169 DOI: 10.3389/Fimmu.2019.00500  0.544
2018 Koujah L, Suryawanshi RK, Shukla D. Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea. Cellular and Molecular Life Sciences : Cmls. PMID 30327839 DOI: 10.1007/S00018-018-2938-1  0.643
2018 Naqvi AR, Shango J, Seal A, Shukla D, Nares S. Herpesviruses and MicroRNAs: New Pathogenesis Factors in Oral Infection and Disease? Frontiers in Immunology. 9: 2099. PMID 30319604 DOI: 10.3389/Fimmu.2018.02099  0.346
2018 Lobo AM, Agelidis AM, Shukla D. Pathogenesis of herpes simplex keratitis: The host cell response and ocular surface sequelae to infection and inflammation. The Ocular Surface. PMID 30317007 DOI: 10.1016/J.Jtos.2018.10.002  0.602
2018 Hopkins J, Yadavalli T, Agelidis AM, Shukla D. Host Enzymes Heparanase and Cathepsin L Promote Herpes Simplex Virus-2 Release from Cells. Journal of Virology. PMID 30232188 DOI: 10.1128/Jvi.01179-18  0.621
2018 Valyi-Nagy T, Fredericks B, Ravindra A, Hopkins J, Shukla D, Valyi-Nagy K. Herpes simplex virus type 1 infection promotes the growth of a subpopulation of tumor cells in 3D uveal melanoma cultures. Journal of Virology. PMID 30045986 DOI: 10.1128/Jvi.00700-18  0.507
2018 Naqvi AR, Seal A, Shango J, Navarette MB, Martinez G, Chapa G, Hasan S, Yadavalli T, Jaishankar D, Shukla D, Nares S. Herpesvirus-encoded microRNAs detected in human gingiva alter host cell transcriptome and regulate viral infection. Biochimica Et Biophysica Acta. PMID 29550353 DOI: 10.1016/J.Bbagrm.2018.03.001  0.3
2018 Jaishankar D, Yakoub AM, Yadavalli T, Agelidis A, Thakkar N, Hadigal S, Ames J, Shukla D. An off-target effect of BX795 blocks herpes simplex virus type 1 infection of the eye. Science Translational Medicine. 10. PMID 29444978 DOI: 10.1126/Scitranslmed.Aan5861  0.594
2017 Yadavalli T, Agelidis A, Jaishankar D, Mangano K, Thakkar N, Penmetcha K, Shukla D. Targeting Herpes Simplex Virus-1 gD by a DNA Aptamer Can Be an Effective New Strategy to Curb Viral Infection. Molecular Therapy. Nucleic Acids. 9: 365-378. PMID 29246315 DOI: 10.1016/J.Omtn.2017.10.009  0.591
2017 Thakkar N, Yadavalli T, Jaishankar D, Shukla D. Emerging Roles of Heparanase in Viral Pathogenesis. Pathogens (Basel, Switzerland). 6. PMID 28927006 DOI: 10.3390/Pathogens6030043  0.638
2017 Agelidis AM, Hadigal SR, Jaishankar D, Shukla D. Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1. Cell Reports. 20: 439-450. PMID 28700944 DOI: 10.1016/J.Celrep.2017.06.041  0.643
2017 Shah D, Ali M, Shukla D, Jain S, Aakalu VK. Effects of histatin-1 peptide on human corneal epithelial cells. Plos One. 12: e0178030. PMID 28542418 DOI: 10.1371/Journal.Pone.0178030  0.332
2017 Duggal N, Jaishankar D, Yadavalli T, Hadigal S, Mishra YK, Adelung R, Shukla D. Zinc oxide tetrapods inhibit herpes simplex virus infection of cultured corneas. Molecular Vision. 23: 26-38. PMID 28275313  0.482
2017 Thakkar N, Jaishankar D, Agelidis A, Yadavalli T, Mangano K, Patel S, Tekin SZ, Shukla D. Cultured corneas show dendritic spread and restrict herpes simplex virus infection that is not observed with cultured corneal cells. Scientific Reports. 7: 42559. PMID 28198435 DOI: 10.1038/Srep42559  0.639
2016 Jaishankar D, Shukla D. Genital Herpes: Insights into Sexually Transmitted Infectious Disease. Microbial Cell (Graz, Austria). 3: 438-450. PMID 28357380 DOI: 10.15698/Mic2016.09.528  0.576
2016 Yadavalli T, Shukla D. Role of Metal and Metal Oxide Nanoparticles as Diagnostic and Therapeutic Tools for Highly Prevalent Viral Infections. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27575283 DOI: 10.1016/J.Nano.2016.08.016  0.465
2016 Burnham LA, Jaishankar D, Thompson JM, Jones KS, Shukla D, Tiwari V. Liposome-Mediated Herpes Simplex Virus Uptake Is Glycoprotein-D Receptor-Independent but Requires Heparan Sulfate. Frontiers in Microbiology. 7: 973. PMID 27446014 DOI: 10.3389/Fmicb.2016.00973  0.601
2016 Antoine TE, Hadigal SR, Yakoub AM, Mishra YK, Bhattacharya P, Haddad C, Valyi-Nagy T, Adelung R, Prabhakar BS, Shukla D. Intravaginal Zinc Oxide Tetrapod Nanoparticles as Novel Immunoprotective Agents against Genital Herpes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183601 DOI: 10.4049/Jimmunol.1502373  0.5
2016 Chang K, Baginski J, Hassan SF, Volin M, Shukla D, Tiwari V. Filopodia and Viruses: An Analysis of Membrane Processes in Entry Mechanisms. Frontiers in Microbiology. 7: 300. PMID 27014223 DOI: 10.3389/Fmicb.2016.00300  0.623
2016 Jaishankar D, Buhrman JS, Valyi-Nagy T, Gemeinhart RA, Shukla D. Extended Release of an Anti-Heparan Sulfate Peptide From a Contact Lens Suppresses Corneal Herpes Simplex Virus-1 Infection. Investigative Ophthalmology & Visual Science. 57: 169-80. PMID 26780322 DOI: 10.1167/Iovs.15-18365  0.525
2015 Agelidis AM, Shukla D. Cell entry mechanisms of HSV: what we have learned in recent years. Future Virology. 10: 1145-1154. PMID 27066105 DOI: 10.2217/Fvl.15.85  0.573
2015 Yakoub AM, Shukla D. Basal Autophagy Is Required for Herpes simplex Virus-2 Infection. Scientific Reports. 5: 12985. PMID 26248741 DOI: 10.1038/Srep12985  0.602
2015 Hadigal SR, Agelidis AM, Karasneh GA, Antoine TE, Yakoub AM, Ramani VC, Djalilian AR, Sanderson RD, Shukla D. Heparanase is a host enzyme required for herpes simplex virus-1 release from cells. Nature Communications. 6: 6985. PMID 25912399 DOI: 10.1038/Ncomms7985  0.821
2015 Yakoub AM, Shukla D. Herpes Simplex Virus-1 Fine-Tunes Host's Autophagic Response to Infection: A Comprehensive Analysis in Productive Infection Models. Plos One. 10: e0124646. PMID 25894397 DOI: 10.1371/Journal.Pone.0124646  0.622
2015 Yakoub AM, Shukla D. Autophagy stimulation abrogates herpes simplex virus-1 infection. Scientific Reports. 5: 9730. PMID 25856282 DOI: 10.1038/Srep09730  0.634
2015 Baldwin J, Maus E, Zanotti B, Volin MV, Tandon R, Shukla D, Tiwari V. A role for 3-O-sulfated heparan sulfate in promoting human cytomegalovirus infection in human iris cells. Journal of Virology. 89: 5185-92. PMID 25717110 DOI: 10.1128/Jvi.00109-15  0.525
2015 Tiwari V, Tarbutton MS, Shukla D. Diversity of heparan sulfate and HSV entry: basic understanding and treatment strategies. Molecules (Basel, Switzerland). 20: 2707-27. PMID 25665065 DOI: 10.3390/Molecules20022707  0.568
2015 Park PJ, Chang M, Garg N, Zhu J, Chang JH, Shukla D. Corneal lymphangiogenesis in herpetic stromal keratitis. Survey of Ophthalmology. 60: 60-71. PMID 25444520 DOI: 10.1016/J.Survophthal.2014.06.001  0.454
2015 Jaishankar D, Yakoub AM, Bogdanov A, Valyi-Nagy T, Shukla D. Characterization of a proteolytically stable D-peptide that suppresses herpes simplex virus 1 infection: implications for the development of entry-based antiviral therapy. Journal of Virology. 89: 1932-8. PMID 25428865 DOI: 10.1128/Jvi.02979-14  0.578
2015 Yakoub AM, Shukla D. Analysis of Autophagy in HSV-1 Infection of Fibroblast Cells. Plos One. DOI: 10.1371/Journal.Pone.0124646.G002  0.576
2015 Yakoub AM, Shukla D. Analysis of Autophagy in HSV-1 Infection of HeLa Cells. Plos One. DOI: 10.1371/Journal.Pone.0124646.G001  0.57
2015 Baldwin J, Maus E, Zanotti B, Volin MV, Tandon R, Shukla D, Tiwari V. A role for 3-O-sulfated heparan sulfate in promoting human cytomegalovirus infection in human iris cells Journal of Virology. 89: 5185-5192. DOI: 10.1128/JVI.00109-15  0.34
2014 Yakoub AM, Rawal N, Maus E, Baldwin J, Shukla D, Tiwari V. Comprehensive analysis of herpes simplex virus 1 (HSV-1) entry mediated by zebrafish 3-O-Sulfotransferase isoforms: implications for the development of a zebrafish model of HSV-1 infection. Journal of Virology. 88: 12915-22. PMID 25142596 DOI: 10.1128/Jvi.02071-14  0.512
2014 Antoine TE, Yakoub A, Maus E, Shukla D, Tiwari V. Zebrafish 3-O-sulfotransferase-4 generated heparan sulfate mediates HSV-1 entry and spread. Plos One. 9: e87302. PMID 24498308 DOI: 10.1371/Journal.Pone.0087302  0.514
2014 Antoine TE, Jones KS, Dale RM, Shukla D, Tiwari V. Zebrafish: modeling for herpes simplex virus infections. Zebrafish. 11: 17-25. PMID 24266790 DOI: 10.1089/Zeb.2013.0920  0.603
2014 Antoine TE, Shukla D. Inhibition of myosin light chain kinase can be targeted for the development of new therapies against herpes simplex virus type-1 infection. Antiviral Therapy. 19: 15-29. PMID 23813409 DOI: 10.3851/Imp2661  0.546
2013 Park PJ, Antoine TE, Farooq AV, Valyi-Nagy T, Shukla D. An investigative peptide-acyclovir combination to control herpes simplex virus type 1 ocular infection. Investigative Ophthalmology & Visual Science. 54: 6373-81. PMID 23989188 DOI: 10.1167/Iovs.13-12832  0.55
2013 Hadigal S, Shukla D. Exploiting herpes simplex virus entry for novel therapeutics. Viruses. 5: 1447-65. PMID 23752649 DOI: 10.3390/V5061447  0.676
2013 Choudhary S, Burnham L, Thompson JM, Shukla D, Tiwari V. Role of Filopodia in HSV-1 Entry into Zebrafish 3-O-Sulfotransferase-3-Expressing Cells. The Open Virology Journal. 7: 41-8. PMID 23667409 DOI: 10.2174/1874357901307010041  0.554
2013 Coleman JL, Shukla D. Recent advances in vaccine development for herpes simplex virus types I and II. Human Vaccines & Immunotherapeutics. 9: 729-35. PMID 23442925 DOI: 10.4161/Hv.23289  0.429
2013 Antoine TE, Park PJ, Shukla D. Glycoprotein targeted therapeutics: a new era of anti-herpes simplex virus-1 therapeutics. Reviews in Medical Virology. 23: 194-208. PMID 23440920 DOI: 10.1002/Rmv.1740  0.653
2013 Baldwin J, Antoine TE, Shukla D, Tiwari V. Zebrafish encoded 3-O-sulfotransferase-2 generated heparan sulfate serves as a receptor during HSV-1 entry and spread. Biochemical and Biophysical Research Communications. 432: 672-6. PMID 23416072 DOI: 10.1016/J.Bbrc.2013.02.020  0.543
2013 Park PJ, Shukla D. Role of heparan sulfate in ocular diseases. Experimental Eye Research. 110: 1-9. PMID 23410824 DOI: 10.1016/J.Exer.2013.01.015  0.314
2013 Baldwin J, Shukla D, Tiwari V. Members of 3-O-Sulfotransferases (3-OST) Family: A Valuable Tool from Zebrafish to Humans for Understanding Herpes Simplex Virus Entry. The Open Virology Journal. 7: 5-11. PMID 23358893 DOI: 10.2174/1874357901307010005  0.621
2013 Baldwin J, Park PJ, Zanotti B, Maus E, Volin MV, Shukla D, Tiwari V. Susceptibility of human iris stromal cells to herpes simplex virus 1 entry. Journal of Virology. 87: 4091-6. PMID 23345512 DOI: 10.1128/Jvi.03235-12  0.614
2012 Trigilio J, Antoine TE, Paulowicz I, Mishra YK, Adelung R, Shukla D. Tin oxide nanowires suppress herpes simplex virus-1 entry and cell-to-cell membrane fusion. Plos One. 7: e48147. PMID 23110193 DOI: 10.1371/Journal.Pone.0048147  0.62
2012 Antoine TE, Mishra YK, Trigilio J, Tiwari V, Adelung R, Shukla D. Prophylactic, therapeutic and neutralizing effects of zinc oxide tetrapod structures against herpes simplex virus type-2 infection. Antiviral Research. 96: 363-75. PMID 23047013 DOI: 10.1016/J.Antiviral.2012.09.020  0.66
2012 Hubbard S, Choudhary S, Maus E, Shukla D, Swenson S, Markland FS, Tiwari V. Contortrostatin, a homodimeric disintegrin isolated from snake venom inhibits herpes simplex virus entry and cell fusion. Antiviral Therapy. 17: 1319-26. PMID 22875654 DOI: 10.3851/Imp2291  0.512
2012 Tiwari V, Maus E, Sigar IM, Ramsey KH, Shukla D. Role of heparan sulfate in sexually transmitted infections. Glycobiology. 22: 1402-12. PMID 22773448 DOI: 10.1093/Glycob/Cws106  0.574
2012 Farooq AV, Shukla D. Herpes simplex epithelial and stromal keratitis: an epidemiologic update. Survey of Ophthalmology. 57: 448-62. PMID 22542912 DOI: 10.1016/J.Survophthal.2012.01.005  0.433
2012 Ali MM, Karasneh GA, Jarding MJ, Tiwari V, Shukla D. A 3-O-sulfated heparan sulfate binding peptide preferentially targets herpes simplex virus 2-infected cells. Journal of Virology. 86: 6434-43. PMID 22491462 DOI: 10.1128/Jvi.00433-12  0.813
2012 Tiwari V, Shukla D. Nonprofessional phagocytosis can facilitate herpesvirus entry into ocular cells. Clinical & Developmental Immunology. 2012: 651691. PMID 22481969 DOI: 10.1155/2012/651691  0.576
2012 Salameh S, Sheth U, Shukla D. Early events in herpes simplex virus lifecycle with implications for an infection of lifetime. The Open Virology Journal. 6: 1-6. PMID 22291864 DOI: 10.2174/1874357901206010001  0.665
2012 Shukla D. Unraveling the cell entry mechanisms of HSV: therapeutic potential? Future Virology. 7: 427-430. DOI: 10.2217/Fvl.12.33  0.457
2011 Karasneh GA, Shukla D. Herpes simplex virus infects most cell types in vitro: clues to its success. Virology Journal. 8: 481. PMID 22029482 DOI: 10.1186/1743-422X-8-481  0.831
2011 Karasneh GA, Ali M, Shukla D. An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread. Plos One. 6: e25252. PMID 21957484 DOI: 10.1371/Journal.Pone.0025252  0.825
2011 Mishra YK, Adelung R, Röhl C, Shukla D, Spors F, Tiwari V. Virostatic potential of micro-nano filopodia-like ZnO structures against herpes simplex virus-1. Antiviral Research. 92: 305-12. PMID 21893101 DOI: 10.1016/J.Antiviral.2011.08.017  0.587
2011 Tiwari V, Liu J, Valyi-Nagy T, Shukla D. Anti-heparan sulfate peptides that block herpes simplex virus infection in vivo. The Journal of Biological Chemistry. 286: 25406-15. PMID 21596749 DOI: 10.1074/Jbc.M110.201103  0.47
2011 Farooq AV, Shukla D. Corneal latency and transmission of herpes simplex virus-1. Future Virology. 6: 101-108. PMID 21436960 DOI: 10.2217/Fvl.10.74  0.451
2011 Dosa S, Castellanos K, Bacsa S, Gagyi E, Kovacs SK, Valyi-Nagy K, Shukla D, Dermody TS, Valyi-Nagy T. Chronic progressive deficits in neuron size, density and number in the trigeminal ganglia of mice latently infected with herpes simplex virus. Brain Pathology (Zurich, Switzerland). 21: 583-93. PMID 21371157 DOI: 10.1111/J.1750-3639.2011.00485.X  0.473
2011 Bacsa S, Karasneh G, Dosa S, Liu J, Valyi-Nagy T, Shukla D. Syndecan-1 and syndecan-2 play key roles in herpes simplex virus type-1 infection. The Journal of General Virology. 92: 733-43. PMID 21148276 DOI: 10.1099/Vir.0.027052-0  0.826
2010 Shah A, Farooq AV, Tiwari V, Kim MJ, Shukla D. HSV-1 infection of human corneal epithelial cells: receptor-mediated entry and trends of re-infection. Molecular Vision. 16: 2476-86. PMID 21139972  0.528
2010 Tiwari V, Shukla D. Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry. The Journal of General Virology. 91: 3002-9. PMID 20810749 DOI: 10.1099/Vir.0.024166-0  0.538
2010 Farooq AV, Valyi-Nagy T, Shukla D. Mediators and mechanisms of herpes simplex virus entry into ocular cells. Current Eye Research. 35: 445-50. PMID 20465436 DOI: 10.3109/02713681003734841  0.595
2010 Tiwari V, Darmani NA, Yue BY, Shukla D. In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type-1 infection. Phytotherapy Research : Ptr. 24: 1132-40. PMID 20041417 DOI: 10.1002/Ptr.3085  0.613
2010 O'Donnell CD, Kovacs M, Akhtar J, Valyi-Nagy T, Shukla D. Expanding the role of 3-O sulfated heparan sulfate in herpes simplex virus type-1 entry. Virology. 397: 389-98. PMID 20004926 DOI: 10.1016/J.Virol.2009.11.011  0.544
2010 Oh MJ, Akhtar J, Desai P, Shukla D. A role for heparan sulfate in viral surfing. Biochemical and Biophysical Research Communications. 391: 176-81. PMID 19909728 DOI: 10.1016/J.Bbrc.2009.11.027  0.579
2010 Valyi-Nagy K, Dosa S, Kovacs SK, Bacsa S, Voros A, Shukla D, Folberg R, Valyi-Nagy T. Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures. Cancer Gene Therapy. 17: 223-34. PMID 19893596 DOI: 10.1038/Cgt.2009.73  0.465
2010 Farooq AV, Shah A, Shukla D. The role of herpesviruses in ocular infections Virus Adaptation and Treatment. 2: 115-123. DOI: 10.2147/Vaat.S9500  0.599
2009 Kovacs SK, Tiwari V, Prandovszky E, Dosa S, Bacsa S, Valyi-Nagy K, Shukla D, Valyi-Nagy T. Expression of herpes virus entry mediator (HVEM) in the cornea and trigeminal ganglia of normal and HSV-1 infected mice. Current Eye Research. 34: 896-904. PMID 19895317 DOI: 10.3109/02713680903184250  0.562
2009 Shukla D. Viral entry mechanisms: simplicity drives complexity. The Febs Journal. 276: 7205. PMID 19878309 DOI: 10.1111/J.1742-4658.2009.07399.X  0.568
2009 Akhtar J, Shukla D. Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry. The Febs Journal. 276: 7228-36. PMID 19878306 DOI: 10.1111/J.1742-4658.2009.07402.X  0.668
2009 Tiwari V, Darmani NA, Thrush GR, Shukla D. An unusual dependence of human herpesvirus-8 glycoproteins-induced cell-to-cell fusion on heparan sulfate. Biochemical and Biophysical Research Communications. 390: 382-7. PMID 19747451 DOI: 10.1016/J.Bbrc.2009.08.174  0.477
2009 O'Donnell CD, Shukla D. A novel function of heparan sulfate in the regulation of cell-cell fusion. The Journal of Biological Chemistry. 284: 29654-65. PMID 19726670 DOI: 10.1074/Jbc.M109.037960  0.499
2009 Tiwari V, Shukla SY, Shukla D. A sugar binding protein cyanovirin-N blocks herpes simplex virus type-1 entry and cell fusion. Antiviral Research. 84: 67-75. PMID 19665490 DOI: 10.1016/J.Antiviral.2009.07.014  0.545
2009 Shukla SY, Singh YK, Shukla D. Role of nectin-1, HVEM, and PILR-alpha in HSV-2 entry into human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 50: 2878-87. PMID 19234349 DOI: 10.1167/Iovs.08-2981  0.532
2008 O'Donnell CD, Shukla D. The Importance of Heparan Sulfate in Herpesvirus Infection. Virologica Sinica. 23: 383-393. PMID 19956628 DOI: 10.1007/S12250-008-2992-1  0.632
2008 Naithani R, Huma LC, Holland LE, Shukla D, McCormick DL, Mehta RG, Moriarty RM. Antiviral activity of phytochemicals: a comprehensive review. Mini Reviews in Medicinal Chemistry. 8: 1106-33. PMID 18855727 DOI: 10.2174/138955708785909943  0.379
2008 Tiwari V, Oh MJ, Kovacs M, Shukla SY, Valyi-Nagy T, Shukla D. Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells. The Febs Journal. 275: 5272-85. PMID 18803666 DOI: 10.1111/J.1742-4658.2008.06655.X  0.62
2008 Dixit R, Tiwari V, Shukla D. Herpes simplex virus type 1 induces filopodia in differentiated P19 neural cells to facilitate viral spread. Neuroscience Letters. 440: 113-8. PMID 18554796 DOI: 10.1016/J.Neulet.2008.05.031  0.621
2008 Akhtar J, Tiwari V, Oh MJ, Kovacs M, Jani A, Kovacs SK, Valyi-Nagy T, Shukla D. HVEM and nectin-1 are the major mediators of herpes simplex virus 1 (HSV-1) entry into human conjunctival epithelium. Investigative Ophthalmology & Visual Science. 49: 4026-35. PMID 18502984 DOI: 10.1167/Iovs.08-1807  0.631
2008 Copeland R, Balasubramaniam A, Tiwari V, Zhang F, Bridges A, Linhardt RJ, Shukla D, Liu J. Using a 3-O-sulfated heparin octasaccharide to inhibit the entry of herpes simplex virus type 1. Biochemistry. 47: 5774-83. PMID 18457417 DOI: 10.1021/Bi800205T  0.532
2008 Prandovszky E, Horváth S, Gellért L, Kovács SK, Janka Z, Toldi J, Shukla D, Vályi-Nagy T. Nectin-1 (HveC) is expressed at high levels in neural subtypes that regulate radial migration of cortical and cerebellar neurons of the developing human and murine brain. Journal of Neurovirology. 14: 164-72. PMID 18444088 DOI: 10.1080/13550280801898672  0.39
2007 Kavouras JH, Prandovszky E, Valyi-Nagy K, Kovacs SK, Tiwari V, Kovacs M, Shukla D, Valyi-Nagy T. Herpes simplex virus type 1 infection induces oxidative stress and the release of bioactive lipid peroxidation by-products in mouse P19N neural cell cultures. Journal of Neurovirology. 13: 416-25. PMID 17994426 DOI: 10.1080/13550280701460573  0.552
2007 Tiwari V, ten Dam GB, Yue BY, van Kuppevelt TH, Shukla D. Role of 3-O-sulfated heparan sulfate in virus-induced polykaryocyte formation. Febs Letters. 581: 4468-72. PMID 17765228 DOI: 10.1016/J.Febslet.2007.08.029  0.527
2007 Tiwari V, Shukla SY, Yue BY, Shukla D. Herpes simplex virus type 2 entry into cultured human corneal fibroblasts is mediated by herpesvirus entry mediator. The Journal of General Virology. 88: 2106-10. PMID 17622611 DOI: 10.1099/Vir.0.82830-0  0.629
2007 Raghuraman A, Tiwari V, Zhao Q, Shukla D, Debnath AK, Desai UR. Viral inhibition studies on sulfated lignin, a chemically modified biopolymer and a potential mimic of heparan sulfate. Biomacromolecules. 8: 1759-63. PMID 17439173 DOI: 10.1021/Bm0701651  0.352
2007 Tiwari V, O'donnell C, Copeland RJ, Scarlett T, Liu J, Shukla D. Soluble 3-O-sulfated heparan sulfate can trigger herpes simplex virus type 1 entry into resistant Chinese hamster ovary (CHO-K1) cells. The Journal of General Virology. 88: 1075-9. PMID 17374750 DOI: 10.1099/Vir.0.82476-0  0.567
2006 Clement C, Tiwari V, Scanlan PM, Valyi-Nagy T, Yue BY, Shukla D. A novel role for phagocytosis-like uptake in herpes simplex virus entry. The Journal of Cell Biology. 174: 1009-21. PMID 17000878 DOI: 10.1083/Jcb.200509155  0.616
2006 Tiwari V, Clement C, Xu D, Valyi-Nagy T, Yue BY, Liu J, Shukla D. Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts. Journal of Virology. 80: 8970-80. PMID 16940509 DOI: 10.1128/Jvi.00296-06  0.609
2006 Shukla D, Scanlan PM, Tiwari V, Sheth V, Clement C, Guzman-Hartman G, Dermody TS, Valyi-Nagy T. Expression of nectin-1 in normal and herpes simplex virus type 1-infected murine brain. Applied Immunohistochemistry & Molecular Morphology : Aimm / Official Publication of the Society For Applied Immunohistochemistry. 14: 341-7. PMID 16932027 DOI: 10.1097/00129039-200609000-00014  0.499
2006 O'Donnell CD, Tiwari V, Oh MJ, Shukla D. A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread. Virology. 346: 452-459. PMID 16336986 DOI: 10.1016/J.Virol.2005.11.003  0.566
2005 Tiwari V, O'Donnell CD, Oh MJ, Valyi-Nagy T, Shukla D. A role for 3-O-sulfotransferase isoform-4 in assisting HSV-1 entry and spread. Biochemical and Biophysical Research Communications. 338: 930-7. PMID 16259945 DOI: 10.1016/J.Bbrc.2005.10.056  0.542
2005 Tiwari V, Clement C, Scanlan PM, Kowlessur D, Yue BY, Shukla D. A role for herpesvirus entry mediator as the receptor for herpes simplex virus 1 entry into primary human trabecular meshwork cells. Journal of Virology. 79: 13173-9. PMID 16189018 DOI: 10.1128/Jvi.79.20.13173-13179.2005  0.624
2005 Raghuraman A, Tiwari V, Thakkar JN, Gunnarsson GT, Shukla D, Hindle M, Desai UR. Structural characterization of a serendipitously discovered bioactive macromolecule, lignin sulfate. Biomacromolecules. 6: 2822-32. PMID 16153124 DOI: 10.1021/Bm0503064  0.402
2005 Scanlan PM, Tiwari V, Bommireddy S, Shukla D. Spinoculation of heparan sulfate deficient cells enhances HSV-1 entry, but does not abolish the need for essential glycoproteins in viral fusion. Journal of Virological Methods. 128: 104-12. PMID 15908019 DOI: 10.1016/J.Jviromet.2005.04.008  0.569
2005 Xu D, Tiwari V, Xia G, Clement C, Shukla D, Liu J. Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1. The Biochemical Journal. 385: 451-9. PMID 15303968 DOI: 10.1042/Bj20040908  0.43
2004 Valyi-Nagy T, Sheth V, Clement C, Tiwari V, Scanlan P, Kavouras JH, Leach L, Guzman-Hartman G, Dermody TS, Shukla D. Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye. Current Eye Research. 29: 303-9. PMID 15590476 DOI: 10.1080/02713680490516756  0.514
2004 Tiwari V, Clement C, Duncan MB, Chen J, Liu J, Shukla D. A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1. The Journal of General Virology. 85: 805-9. PMID 15039523 DOI: 10.1099/Vir.0.19641-0  0.584
2003 Yoon M, Zago A, Shukla D, Spear PG. Mutations in the N termini of herpes simplex virus type 1 and 2 gDs alter functional interactions with the entry/fusion receptors HVEM, nectin-2, and 3-O-sulfated heparan sulfate but not with nectin-1. Journal of Virology. 77: 9221-31. PMID 12915538 DOI: 10.1128/Jvi.77.17.9221-9231.2003  0.523
2003 Scanlan PM, Tiwari V, Bommireddy S, Shukla D. Cellular expression of gH confers resistance to herpes simplex virus type-1 entry. Virology. 312: 14-24. PMID 12890617 DOI: 10.1016/S0042-6822(03)00176-4  0.503
2002 Xia G, Chen J, Tiwari V, Ju W, Li JP, Malmstrom A, Shukla D, Liu J. Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1. The Journal of Biological Chemistry. 277: 37912-9. PMID 12138164 DOI: 10.1074/Jbc.M204209200  0.508
2001 Yabe T, Shukla D, Spear PG, Rosenberg RD, Seeberger PH, Shworak NW. Portable sulphotransferase domain determines sequence specificity of heparan sulphate 3-O-sulphotransferases. The Biochemical Journal. 359: 235-41. PMID 11563988 DOI: 10.1042/0264-6021:3590235  0.326
2001 Haarr L, Shukla D, Rødahl E, Dal Canto MC, Spear PG. Transcription from the gene encoding the herpesvirus entry receptor nectin-1 (HveC) in nervous tissue of adult mouse. Virology. 287: 301-9. PMID 11531408 DOI: 10.1006/Viro.2001.1041  0.412
2001 Shukla D, Spear PG. Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry. The Journal of Clinical Investigation. 108: 503-10. PMID 11518721 DOI: 10.1172/Jci13799  0.609
2000 Shukla D, Dal Canto MC, Rowe CL, Spear PG. Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor for alphaherpesvirus entry. Journal of Virology. 74: 11773-81. PMID 11090177 DOI: 10.1128/Jvi.74.24.11773-11781.2000  0.496
1999 Shukla D, Liu J, Blaiklock P, Shworak NW, Bai X, Esko JD, Cohen GH, Eisenberg RJ, Rosenberg RD, Spear PG. A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry. Cell. 99: 13-22. PMID 10520990 DOI: 10.1016/S0092-8674(00)80058-6  0.537
1999 Shukla D, Rowe CL, Dong Y, Racaniello VR, Spear PG. The murine homolog (Mph) of human herpesvirus entry protein B (HveB) mediates entry of pseudorabies virus but not herpes simplex virus types 1 and 2. Journal of Virology. 73: 4493-7. PMID 10196354 DOI: 10.1128/Jvi.73.5.4493-4497.1999  0.558
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