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Lee Bardwell - Publications

Affiliations: 
Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Biochemistry
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bardwell L, Thorner J. Mitogen-activated protein kinase (MAPK) cascades-A yeast perspective. The Enzymes. 54: 137-170. PMID 37945169 DOI: 10.1016/bs.enz.2023.07.001  0.523
2023 Bardwell AJ, Paul M, Yoneda KC, Andrade-Ludeña MD, Nguyen OT, Fruman D, Bardwell L. The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase. The Biochemical Journal. PMID 37145016 DOI: 10.1042/BCJ20220493  0.315
2022 Bardwell AJ, Wu B, Sarin KY, Waterman ML, Atwood SX, Bardwell L. ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1. Life Science Alliance. 5. PMID 35831023 DOI: 10.26508/lsa.202101353  0.514
2020 Lagunes L, Bardwell L, Enciso GA. Effect of magnitude and variability of energy of activation in multisite ultrasensitive biochemical processes. Plos Computational Biology. 16: e1007966. PMID 32760072 DOI: 10.1371/Journal.Pcbi.1007966  0.444
2019 Bardwell L. Pseudokinases: Flipping the ATP for AMPylation. Current Biology : Cb. 29: R23-R25. PMID 30620911 DOI: 10.1016/J.Cub.2018.11.018  0.413
2019 Syed A, Lukacsovich T, Pomeroy M, Bardwell AJ, Decker GT, Waymire KG, Purcell J, Huang W, Gui J, Padilla EM, Park C, Paul A, Pham TBT, Rodriguez Y, Wei S, ... ... Bardwell L, et al. Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila. Developmental Biology. 445: 37-53. PMID 30539716 DOI: 10.1016/J.Ydbio.2018.10.016  0.345
2017 Bardwell AJ, Lagunes L, Zebarjedi R, Bardwell L. The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2. The Journal of Biological Chemistry. PMID 28396345 DOI: 10.1074/Jbc.M116.767087  0.548
2015 Bardwell AJ, Bardwell L. Two hydrophobic residues can determine the specificity of mitogen-activated protein kinase docking interactions. The Journal of Biological Chemistry. 290: 26661-74. PMID 26370088 DOI: 10.1074/Jbc.M115.691436  0.497
2014 Mattson-Hoss MK, Niitani Y, Gordon EA, Jun Y, Bardwell L, Tomishige M, Gross SP. CK2 activates kinesin via induction of a conformational change. Proceedings of the National Academy of Sciences of the United States of America. 111: 7000-5. PMID 24782540 DOI: 10.1073/Pnas.1321419111  0.378
2013 Gordon EA, Whisenant TC, Zeller M, Kaake RM, Gordon WM, Krotee P, Patel V, Huang L, Baldi P, Bardwell L. Combining docking site and phosphosite predictions to find new substrates: identification of smoothelin-like-2 (SMTNL2) as a c-Jun N-terminal kinase (JNK) substrate. Cellular Signalling. 25: 2518-29. PMID 23981301 DOI: 10.1016/J.Cellsig.2013.08.004  0.774
2012 Chan C, Liu X, Wang L, Bardwell L, Nie Q, Enciso G. Protein scaffolds can enhance the bistability of multisite phosphorylation systems. Plos Computational Biology. 8: e1002551. PMID 22737061 DOI: 10.1371/Journal.Pcbi.1002551  0.505
2012 Xu J, Reddy BJ, Anand P, Shu Z, Cermelli S, Mattson MK, Tripathy SK, Hoss MT, James NS, King SJ, Huang L, Bardwell L, Gross SP. Casein kinase 2 reverses tail-independent inactivation of kinesin-1. Nature Communications. 3: 754. PMID 22453827 DOI: 10.1038/Ncomms1760  0.498
2011 Hetherington AM, Bardwell L. Plant signalling pathways: a comparative evolutionary overview. Current Biology : Cb. 21: R317-9. PMID 21549953 DOI: 10.1016/J.Cub.2011.04.013  0.351
2011 Bardwell L. Synthetic biology: modulating the MAP kinase module. Current Biology : Cb. 21: R249-51. PMID 21481758 DOI: 10.1016/J.Cub.2011.02.042  0.431
2011 Xu J, Reddy B, Anand P, Shu Z, Cermelli S, Mattson M, Tripathy S, Hoss M, James N, King S, Huang L, Bardwell L, Gross S. 2011 ASCB Annual Meeting abstracts Molecular Biology of the Cell. 22: 1507. DOI: 10.1091/Mbc.E11-10-0886  0.496
2011 Xu J, Shu Z, Anand P, Reddy BJ, Cermelli S, Whisenant T, King SJ, Bardwell L, Huang L, Gross SP. Casein Kinase 2 Reverses Tail-Independent Inhibition of Kinesin-1 Biophysical Journal. 100: 120a. DOI: 10.1016/j.bpj.2010.12.863  0.387
2010 Compani B, Su T, Chang I, Cheng J, Shah KH, Whisenant T, Dou Y, Bergmann A, Cheong R, Wold B, Bardwell L, Levchenko A, Baldi P, Mjolsness E. A scalable and integrative system for pathway bioinformatics and systems biology. Advances in Experimental Medicine and Biology. 680: 523-34. PMID 20865537 DOI: 10.1007/978-1-4419-5913-3_58  0.712
2010 Whisenant TC, Ho DT, Benz RW, Rogers JS, Kaake RM, Gordon EA, Huang L, Baldi P, Bardwell L. Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors. Plos Computational Biology. 6. PMID 20865152 DOI: 10.1371/Journal.Pcbi.1000908  0.787
2010 Haney S, Bardwell L, Nie Q. Ultrasensitive responses and specificity in cell signaling. Bmc Systems Biology. 4: 119. PMID 20735856 DOI: 10.1186/1752-0509-4-119  0.467
2010 Liu X, Bardwell L, Nie Q. A combination of multisite phosphorylation and substrate sequestration produces switchlike responses. Biophysical Journal. 98: 1396-407. PMID 20409458 DOI: 10.1016/J.Bpj.2009.12.4307  0.562
2009 Bardwell AJ, Frankson E, Bardwell L. Selectivity of docking sites in MAPK kinases. The Journal of Biological Chemistry. 284: 13165-73. PMID 19196711 DOI: 10.1074/Jbc.M900080200  0.544
2008 Hilioti Z, Sabbagh W, Paliwal S, Bergmann A, Goncalves MD, Bardwell L, Levchenko A. Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis. Current Biology : Cb. 18: 1700-6. PMID 18976914 DOI: 10.1016/J.Cub.2008.09.027  0.796
2008 Bardwell L. Signal transduction: turning a switch into a rheostat. Current Biology : Cb. 18: R910-2. PMID 18957235 DOI: 10.1016/J.Cub.2008.07.082  0.474
2008 Hilioti Z, Sabbagh W, Paliwal S, Bergmann A, Goncalves MD, Bardwell L, Levchenko A. Oscillatory Phosphorylation of Yeast Fus3 MAP Kinase Controls Periodic Gene Expression and Morphogenesis (DOI:10.1016/j.cub.2008.09.027) Current Biology. 18: 1897. DOI: 10.1016/j.cub.2008.11.024  0.366
2007 Bardwell L, Zou X, Nie Q, Komarova NL. Mathematical models of specificity in cell signaling. Biophysical Journal. 92: 3425-41. PMID 17325015 DOI: 10.1529/Biophysj.106.090084  0.519
2006 Bardwell L. Mechanisms of MAPK signalling specificity Biochemical Society Transactions. 34: 837-841. PMID 17052210 DOI: 10.1042/Bst0340837  0.622
2006 Bardwell L. G-protein signaling: a new branch in an old pathway. Current Biology : Cb. 16: R853-5. PMID 17027484 DOI: 10.1016/J.Cub.2006.08.072  0.482
2006 Bardwell L, Shah K. Analysis of mitogen-activated protein kinase activation and interactions with regulators and substrates. Methods (San Diego, Calif.). 40: 213-23. PMID 16884917 DOI: 10.1016/J.Ymeth.2006.06.008  0.752
2006 Ho DT, Bardwell AJ, Grewal S, Iverson C, Bardwell L. Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases. The Journal of Biological Chemistry. 281: 13169-79. PMID 16533805 DOI: 10.1074/Jbc.M601010200  0.501
2006 Grewal S, Molina DM, Bardwell L. Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo. Cellular Signalling. 18: 123-34. PMID 15979847 DOI: 10.1016/J.Cellsig.2005.04.001  0.768
2005 Komarova NL, Zou X, Nie Q, Bardwell L. A theoretical framework for specificity in cell signaling. Molecular Systems Biology. 1: 2005.0023. PMID 16729058 DOI: 10.1038/Msb4100031  0.475
2005 Molina DM, Grewal S, Bardwell L. Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation. The Journal of Biological Chemistry. 280: 42051-60. PMID 16246839 DOI: 10.1074/Jbc.M510590200  0.783
2005 Flatauer LJ, Zadeh SF, Bardwell L. Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiae. Molecular and Cellular Biology. 25: 1793-803. PMID 15713635 DOI: 10.1128/Mcb.25.5.1793-1803.2005  0.79
2005 Bardwell L. A walk-through of the yeast mating pheromone response pathway. Peptides. 26: 339-50. PMID 15690603 DOI: 10.1016/J.Peptides.2004.10.002  0.536
2004 Bardwell L. A walk-through of the yeast mating pheromone response pathway. Peptides. 25: 1465-76. PMID 15374648 DOI: 10.1016/j.peptides.2003.10.022  0.448
2004 Cullen PJ, Sabbagh W, Graham E, Irick MM, van Olden EK, Neal C, Delrow J, Bardwell L, Sprague GF. A signaling mucin at the head of the Cdc42- and MAPK-dependent filamentous growth pathway in yeast. Genes & Development. 18: 1695-708. PMID 15256499 DOI: 10.1101/Gad.1178604  0.811
2004 Kusari AB, Molina DM, Sabbagh W, Lau CS, Bardwell L. A conserved protein interaction network involving the yeast MAP kinases Fus3 and Kss1. The Journal of Cell Biology. 164: 267-77. PMID 14734536 DOI: 10.1083/Jcb.200310021  0.798
2004 Bardwell AJ, Abdollahi M, Bardwell L. Anthrax lethal factor-cleavage products of MAPK (mitogen-activated protein kinase) kinases exhibit reduced binding to their cognate MAPKs. The Biochemical Journal. 378: 569-77. PMID 14616089 DOI: 10.1042/Bj20031382  0.635
2003 Ho DT, Bardwell AJ, Abdollahi M, Bardwell L. A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates. The Journal of Biological Chemistry. 278: 32662-72. PMID 12788955 DOI: 10.1074/Jbc.M304229200  0.518
2003 Bardwell AJ, Abdollahi M, Bardwell L. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity. The Biochemical Journal. 370: 1077-85. PMID 12529172 DOI: 10.1042/Bj20021806  0.627
2001 Sabbagh W, Flatauer LJ, Bardwell AJ, Bardwell L. Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation. Molecular Cell. 8: 683-91. PMID 11583629 DOI: 10.1016/S1097-2765(01)00322-7  0.735
2001 Bardwell AJ, Flatauer LJ, Matsukuma K, Thorner J, Bardwell L. A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. The Journal of Biological Chemistry. 276: 10374-86. PMID 11134045 DOI: 10.1074/Jbc.M010271200  0.792
1998 Bardwell L, Cook JG, Zhu-Shimoni JX, Voora D, Thorner J. Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 15400-5. PMID 9860980 DOI: 10.1073/Pnas.95.26.15400  0.541
1998 Bardwell L, Cook JG, Voora D, Baggott DM, Martinez AR, Thorner J. Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes & Development. 12: 2887-98. PMID 9744865 DOI: 10.1101/Gad.12.18.2887  0.597
1997 Cook JG, Bardwell L, Thorner J. Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature. 390: 85-8. PMID 9363895 DOI: 10.1038/36355  0.573
1996 Cook JG, Bardwell L, Kron SJ, Thorner J. Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes & Development. 10: 2831-48. PMID 8918885 DOI: 10.1101/Gad.10.22.2831  0.532
1996 Bardwell L, Thorner J. A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. Trends in Biochemical Sciences. 21: 373-4. PMID 8918190 DOI: 10.1016/S0968-0004(96)30032-7  0.396
1996 Bardwell L, Cook JG, Chang EC, Cairns BR, Thorner J. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Molecular and Cellular Biology. 16: 3637-50. PMID 8668180 DOI: 10.1128/Mcb.16.7.3637  0.659
1994 Bardwell AJ, Bardwell L, Iyer N, Svejstrup JQ, Feaver WJ, Kornberg RD, Friedberg EC. Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH) Molecular and Cellular Biology. 14: 3569-3576. PMID 8196602 DOI: 10.1128/Mcb.14.6.3569  0.346
1994 Bardwell L, Bardwell AJ, Feaver WJ, Svejstrup JQ, Kornberg RD, Friedberg EC. Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: Implications for the structure and function of transcription/ repair factor b Proceedings of the National Academy of Sciences of the United States of America. 91: 3926-3930. PMID 8171014 DOI: 10.1073/Pnas.91.9.3926  0.371
1994 Bardwell L, Cook JG, Inouye CJ, Thorner J. Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Developmental Biology. 166: 363-79. PMID 7813763 DOI: 10.1006/Dbio.1994.1323  0.571
1993 Tomkinson AE, Bardwell AJ, Bardwell L, Tappe NJ, Friedberg EC. Yeast DNA repair and recombination proteins Rad1 and Rad1O constitute a single-stranded-DNA endonuclease Nature. 362: 860-862. PMID 8479526 DOI: 10.1038/362860A0  0.302
1993 Naegeli H, Bardwell L, Friedberg EC. Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: Implications for the role of a DNA helicase in damage-specific incision of DNA Biochemistry. 32: 613-621. PMID 8380702 DOI: 10.1021/Bi00053A029  0.305
1993 Bardwell AJ, Bardwell L, Johnson DK, Friedberg EC. Yeast DNA recombination and repair proteins Rad1 and Rad10 constitute a complex in vivo mediated by localized hydrophobic domains Molecular Microbiology. 8: 1177-1188. PMID 8361362 DOI: 10.1111/J.1365-2958.1993.Tb01662.X  0.37
1993 Feaver WJ, Svejstrup JQ, Bardwell L, Bardwell AJ, Buratowski S, Gulyas KD, Donahue TF, Friedberg EC, Kornberg RD. Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell. 75: 1379-87. PMID 8269516 DOI: 10.1016/0092-8674(93)90624-Y  0.382
1992 Bardwell L, Jane Cooper A, Friedberg EC. Stable and specific association between the yeast recombination and DNA repair proteins RAD1 and RAD10 in vitro Molecular and Cellular Biology. 12: 3041-3049. PMID 1620114 DOI: 10.1128/Mcb.12.7.3041  0.387
1990 Bardwell L, Burtscher H, Weiss WA, Nicolet CM, Friedberg EC. Characterization of the RAD10 gene of Saccharomyces cerevisiae and purification of Rad10 protein Biochemistry. 29: 3119-3126. PMID 2110825 DOI: 10.1021/Bi00464A031  0.322
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