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Adrienne L. Watson, Ph.D. - Publications

Affiliations: 
2013 Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Genetics, Cell Biology, Molecular Biology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Osum SH, Oribamise EI, Corbière SMAS, Taisto M, Jubenville T, Coutts A, Kirstein MN, Fisher J, Moertel C, Du M, Bedwell D, Largaespada DA, Watson AL. Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 1. Molecular Therapy. Nucleic Acids. 33: 227-239. PMID 37520682 DOI: 10.1016/j.omtn.2023.06.018  0.585
2021 Osum SH, Coutts AW, Duerre DJ, Tschida BR, Kirstein MN, Fisher J, Bell WR, Delpuech O, Smith PD, Widemann BC, Moertel CL, Largaespada DA, Watson AL. Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo. Neuro-Oncology Advances. 3: vdab020. PMID 33978635 DOI: 10.1093/noajnl/vdab020  0.456
2021 Galvin R, Watson AL, Largaespada DA, Ratner N, Osum S, Moertel CL. Neurofibromatosis in the Era of Precision Medicine: Development of MEK Inhibitors and Recent Successes with Selumetinib. Current Oncology Reports. 23: 45. PMID 33721151 DOI: 10.1007/s11912-021-01032-y  0.48
2021 Osum SH, Watson AL, Largaespada DA. Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1. International Journal of Molecular Sciences. 22. PMID 33669386 DOI: 10.3390/ijms22041954  0.546
2020 Watson AL, Keller BJ, Williams KA, Damle NN, Finnerty SJ, Anderson LK, Greeley AD, Keng VW, Rahrmann EP, Halfond AL, Powell NM, Collins MH, Rizvi T, Moertel CL, Ratner N, et al. Correction: Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity. Oncotarget. 11: 3618-3620. PMID 33062197 DOI: 10.18632/oncotarget.27349  0.753
2019 Nicholls PK, Schorle H, Naqvi S, Hu YC, Fan Y, Carmell MA, Dobrinski I, Watson AL, Carlson DF, Fahrenkrug SC, Page DC. Mammalian germ cells are determined after PGC colonization of the nascent gonad. Proceedings of the National Academy of Sciences of the United States of America. PMID 31754036 DOI: 10.1073/Pnas.1910733116  0.42
2019 Rathe SK, Popescu FE, Johnson JE, Watson AL, Marko TA, Moriarity BS, Ohlfest JR, Largaespada DA. Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas. Scientific Reports. 9: 358. PMID 30674975 DOI: 10.1038/S41598-018-36840-Z  0.737
2019 Osum S, Stemmer-Rachamimov A, Widemann B, Dombi E, Vitte J, Dahiya S, Rizvi T, Ratner N, Messiaen L, Gutmann D, Giovannini M, Moertel C, Largaespada D, Watson A. TMOD-23. PRECLINICAL DRUG EVALUATION IN A GENETICALLY ENGINEERED MINIPIG MODEL OF NEUROFIBROMATOSIS TYPE 1 Neuro-Oncology. 21: vi267-vi267. DOI: 10.1093/Neuonc/Noz175.1122  0.582
2019 Tschida B, Duerre D, Taisto M, Solin S, Watson A. TMOD-17. A SWINE MODEL OF GLIOBLASTOMA INDUCED BY SOMATIC GENE MODIFICATION Neuro-Oncology. 21: vi266-vi266. DOI: 10.1093/Neuonc/Noz175.1116  0.522
2019 Nicholls P, Schorle H, Naqvi S, Hu Y, Yuting F, Carmell M, Dobrinski I, Watson A, Carlson D, Fahrenkrug S, Page D. Germ cell commitment occurs after PGC colonization of the gonad in mammals European Urology Supplements. 18: 11-12. DOI: 10.1016/S1569-9056(19)32485-6  0.333
2018 Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, ... ... Watson AL, et al. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Communications Biology. 1: 158. PMID 30302402 DOI: 10.1038/s42003-018-0163-y  0.524
2017 Carlson M, Watson AL, Anderson L, Largaespada DA, Provenzano PP. Multiphoton fluorescence lifetime imaging of chemotherapy distribution in solid tumors. Journal of Biomedical Optics. 22: 1-9. PMID 29188660 DOI: 10.1117/1.Jbo.22.11.116010  0.536
2017 Isakson S, Coutts A, Largaespada D, Watson A. TMOD-43. A PORCINE MODEL OF NEUROFIBROMATOSIS TYPE I-ASSOCIATED NERVOUS SYSTEM TUMORS Neuro-Oncology. 19: vi263-vi263. DOI: 10.1093/Neuonc/Nox168.1079  0.571
2016 Watson AL, Carlson DF, Largaespada DA, Hackett PB, Fahrenkrug SC. Engineered Swine Models of Cancer. Frontiers in Genetics. 7: 78. PMID 27242889 DOI: 10.3389/Fgene.2016.00078  0.508
2014 Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis. The American Journal of Pathology. 184: 2082-98. PMID 24832557 DOI: 10.1016/J.Ajpath.2014.04.006  0.789
2014 Moriarity BS, Rahrmann EP, Beckmann DA, Conboy CB, Watson AL, Carlson DF, Olson ER, Hyland KA, Fahrenkrug SC, McIvor RS, Largaespada DA. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. Plos One. 9: e96114. PMID 24798371 DOI: 10.1371/Journal.Pone.0096114  0.746
2014 Watson AL, Anderson LK, Greeley AD, Keng VW, Rahrmann EP, Halfond AL, Powell NM, Collins MH, Rizvi T, Moertel CL, Ratner N, Largaespada DA. Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity. Oncotarget. 5: 1502-14. PMID 24681606 DOI: 10.18632/Oncotarget.1609  0.768
2013 Rathe SK, Johnson JE, Silverstein KA, Erdmann JJ, Watson AL, Popescu FE, Ohlfest JR, Largaespada DA. MMuFLR: missense mutation and frameshift location reporter. Bioinformatics (Oxford, England). 29: 2353-4. PMID 23825368 DOI: 10.1093/Bioinformatics/Btt385  0.709
2013 Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nature Genetics. 45: 756-66. PMID 23685747 DOI: 10.1038/Ng.2641  0.784
2013 Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, et al. Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance. Cancer Discovery. 3: 674-89. PMID 23535903 DOI: 10.1158/2159-8290.Cd-13-0081  0.777
2013 Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Abstract 354: Conditional inactivation of Pten and overexpression of EGFR in Schwann cells results in early high-grade peripheral nerve sheath tumor development. Cancer Research. 73: 354-354. DOI: 10.1158/1538-7445.Am2013-354  0.79
2012 Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST. Sarcoma. 2012: 620834. PMID 23319880 DOI: 10.1155/2012/620834  0.791
2012 Keng VW, Rahrmann EP, Watson AL, Tschida BR, Moertel CL, Jessen WJ, Rizvi TA, Collins MH, Ratner N, Largaespada DA. PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors. Cancer Research. 72: 3405-13. PMID 22700876 DOI: 10.1158/0008-5472.Can-11-4092  0.797
2012 Dimitroff B, Howe K, Watson A, Campion B, Lee HG, Zhao N, O'Connor MB, Neufeld TP, Selleck SB. Diet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis. Plos One. 7: e30722. PMID 22319582 DOI: 10.1371/Journal.Pone.0030722  0.338
2010 Adhikari N, Basi DL, Townsend D, Rusch M, Mariash A, Mullegama S, Watson A, Larson J, Tan S, Lerman B, Esko JD, Selleck SB, Hall JL. Heparan sulfate Ndst1 regulates vascular smooth muscle cell proliferation, vessel size and vascular remodeling. Journal of Molecular and Cellular Cardiology. 49: 287-93. PMID 20206635 DOI: 10.1016/J.Yjmcc.2010.02.022  0.537
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