Lynn M. Bekris, Ph.D. - Publications

Affiliations: 
2005 University of Washington, Seattle, Seattle, WA 
Area:
Toxicology, Genetics, Immunology, Pathology

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Foraker J, Millard SP, Leong L, Thomson Z, Chen S, Keene CD, Bekris LM, Yu CE. The APOE Gene is Differentially Methylated in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26402071 DOI: 10.3233/JAD-143060  0.52
2015 Bekris LM, Tsuang DW, Peskind ER, Yu CE, Montine TJ, Zhang J, Zabetian CP, Leverenz JB. Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 936-44. PMID 25808939 DOI: 10.1002/Mds.26172  0.52
2015 Jay TR, Miller CM, Cheng PJ, Graham LC, Bemiller S, Broihier ML, Xu G, Margevicius D, Karlo JC, Sousa GL, Cotleur AC, Butovsky O, Bekris L, Staugaitis SM, Leverenz JB, et al. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. The Journal of Experimental Medicine. 212: 287-95. PMID 25732305 DOI: 10.1084/Jem.20142322  0.52
2014 Millard SP, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang D, Yu CE, Peskind ER, Bekris LM. Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects. Neurobiology of Aging. 35: 357-64. PMID 24011543 DOI: 10.1016/J.Neurobiolaging.2013.07.027  0.52
2013 Yu CE, Cudaback E, Foraker J, Thomson Z, Leong L, Lutz F, Gill JA, Saxton A, Kraemer B, Navas P, Keene CD, Montine T, Bekris LM. Epigenetic signature and enhancer activity of the human APOE gene. Human Molecular Genetics. 22: 5036-47. PMID 23892237 DOI: 10.1093/Hmg/Ddt354  0.52
2013 Bekris LM, Lutz F, Montine TJ, Yu CE, Tsuang D, Peskind ER, Leverenz JB. MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 18: 455-66. PMID 23822153 DOI: 10.3109/1354750X.2013.814073  0.52
2013 Li G, Bekris LM, Leong L, Steinbart EJ, Shofer JB, Crane PK, Larson EB, Peskind ER, Bird TD, Yu CE. TOMM40 intron 6 poly-T length, age at onset, and neuropathology of AD in individuals with APOE ε3/ε3. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 554-61. PMID 23183136 DOI: 10.1016/J.Jalz.2012.06.009  0.52
2012 Bekris LM, Millard S, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang DW, Yu CE, Peskind ER. Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 874-83. PMID 22927204 DOI: 10.1002/Ajmg.B.32094  0.52
2012 Bekris LM, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang DW, Montine TJ, Peskind ER, Yu CE. ADAM10 expression and promoter haplotype in Alzheimer's disease. Neurobiology of Aging. 33: 2229.e1-2229.e9. PMID 22572541 DOI: 10.1016/J.Neurobiolaging.2012.03.013  0.52
2012 Meabon JS, Lee A, Meeker KD, Bekris LM, Fujimura RK, Yu CE, Watson GS, Pow DV, Sweet IR, Cook DG. Differential expression of the glutamate transporter GLT-1 in pancreas. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 60: 139-51. PMID 22114258 DOI: 10.1369/0022155411430095  0.52
2012 Bekris LM, Lutz F, Yu CE. Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE. Journal of Human Genetics. 57: 18-25. PMID 22089642 DOI: 10.1038/Jhg.2011.123  0.52
2011 Korvatska O, Estes A, Munson J, Dawson G, Bekris LM, Kohen R, Yu CE, Schellenberg GD, Raskind WH. Mutations in the TSGA14 gene in families with autism spectrum disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 303-11. PMID 21438139 DOI: 10.1002/Ajmg.B.31162  0.52
2011 Bekris LM, Galloway NM, Millard S, Lockhart D, Li G, Galasko DR, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Leverenz JB, Seubert P, Tsuang DW, Peskind ER, et al. Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease. Neurobiology of Aging. 32: 556.e13-23. PMID 21196064 DOI: 10.1016/J.Neurobiolaging.2010.10.020  0.52
2010 Bekris LM, Yu CE, Bird TD, Tsuang DW. Genetics of Alzheimer disease. Journal of Geriatric Psychiatry and Neurology. 23: 213-27. PMID 21045163 DOI: 10.1177/0891988710383571  0.52
2010 Bekris LM, Mata IF, Zabetian CP. The genetics of Parkinson disease. Journal of Geriatric Psychiatry and Neurology. 23: 228-42. PMID 20938043 DOI: 10.1177/0891988710383572  0.52
2010 Örtqvist E, Brooks-Worrell B, Lynch K, Radtke J, Bekris LM, Kockum I, Agardh CD, Cilio CM, Lethagen AL, Persson B, Lernmark A, Reichow J, Oak S, Palmer JP, Hampe CS. Changes in GAD65Ab-specific antiidiotypic antibody levels correlate with changes in C-peptide levels and progression to islet cell autoimmunity Journal of Clinical Endocrinology and Metabolism. 95. PMID 20685858 DOI: 10.1210/Jc.2010-0785  0.52
2010 Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, McCluskey L, Clark CM, Neumann M, et al. The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Archives of Neurology. 67: 161-70. PMID 20142524 DOI: 10.1001/Archneurol.2009.328  0.52
2010 Bekris LM, Galloway NM, Montine TJ, Schellenberg GD, Yu CE. APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 409-17. PMID 19554612 DOI: 10.1002/Ajmg.B.30993  0.52
2010 Bekris LM, Yu CE, Bird TD, Tsuang D. Genetics of Alzheimer's Disease Principles and Practice of Geriatric Psychiatry: Third Edition. 238-251. DOI: 10.1002/9780470669600.ch43  0.52
2009 Li G, Peskind ER, Millard SP, Chi P, Sokal I, Yu CE, Bekris LM, Raskind MA, Galasko DR, Montine TJ. Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects. Plos One. 4: e5424. PMID 19412541 DOI: 10.1371/Journal.Pone.0005424  0.52
2008 Bekris LM, Millard SP, Galloway NM, Vuletic S, Albers JJ, Li G, Galasko DR, DeCarli C, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Tsuang D, Peskind ER, et al. Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. Journal of Alzheimer's Disease : Jad. 13: 255-66. PMID 18430993 DOI: 10.3233/Jad-2008-13303  0.52
2008 Van Deerlin VM, Leverenz JB, Bekris LM, Bird TD, Yuan W, Elman LB, Clay D, Wood EM, Chen-Plotkin AS, Martinez-Lage M, Steinbart E, McCluskey L, Grossman M, Neumann M, Wu IL, et al. TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis. The Lancet. Neurology. 7: 409-16. PMID 18396105 DOI: 10.1016/S1474-4422(08)70071-1  0.52
2007 Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 115: 221-8. PMID 17479437 DOI: 10.1055/S-2007-970574  0.52
2007 Leverenz JB, Yu CE, Montine TJ, Steinbart E, Bekris LM, Zabetian C, Kwong LK, Lee VM, Schellenberg GD, Bird TD. A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology. Brain : a Journal of Neurology. 130: 1360-74. PMID 17439980 DOI: 10.1093/Brain/Awm069  0.52
2007 Bekris LM, Jensen RA, Lagerquist E, Hall TR, Agardh CD, Cilio CM, Lethagen AL, Lernmark A, Robertson JA, Hampe CS. GAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination. Diabetic Medicine : a Journal of the British Diabetic Association. 24: 521-6. PMID 17367313 DOI: 10.1111/J.1464-5491.2007.02091.X  0.52
2007 Hoeldtke RD, Hampe CS, Bekris LM, Hobbs G, Bryner KD, Lernmark A. Antibodies to GAD65 and peripheral nerve function in the DCCT. Journal of Neuroimmunology. 185: 182-9. PMID 17328966 DOI: 10.1016/J.Jneuroim.2007.01.009  0.52
2006 Roach JC, Deutsch K, Li S, Siegel AF, Bekris LM, Einhaus DC, Sheridan CM, Glusman G, Hood L, Lernmark A, Janer M. Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. American Journal of Human Genetics. 79: 614-27. PMID 16960798 DOI: 10.1086/507876  0.52
2006 Zangeneh F, Arora PS, Dyck PJ, Bekris L, Lernmark A, Achenbach SJ, Oberg AL, Rizza RA. Effects of duration of type 2 diabetes mellitus on insulin secretion. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 12: 388-93. PMID 16939949 DOI: 10.4158/Ep.12.4.388  0.52
2006 Bekris LM, Viernes HM, Farin FM, Maier LA, Kavanagh TJ, Takaro TK. Chronic beryllium disease and glutathione biosynthesis genes. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 48: 599-606. PMID 16766924 DOI: 10.1097/01.Jom.0000201845.02369.Ba  0.52
2006 Bekris LM, Kavanagh TJ, Lernmark A. Targeting type 1 diabetes before and at the clinical onset of disease. Endocrine, Metabolic & Immune Disorders Drug Targets. 6: 103-24. PMID 16611168 DOI: 10.2174/187153006776056576  0.52
2005 Bekris LM, Shephard C, Peterson M, Hoehna J, Van Yserloo B, Rutledge E, Farin F, Kavanagh TJ, Lernmark A. Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity. 38: 567-75. PMID 16390810 DOI: 10.1080/08916930500407238  0.52
2005 Padoa CJ, Crowther NJ, Thomas JW, Hall TR, Bekris LM, Torn C, Landin-Olsson M, Ortqvist E, Palmer JP, Lernmark A, Hampe CS. Epitope analysis of insulin autoantibodies using recombinant Fab. Clinical and Experimental Immunology. 140: 564-71. PMID 15932520 DOI: 10.1111/J.1365-2249.2005.02802.X  0.52
2004 Maioli M, Alejandro E, Tonolo G, Gilliam LK, Bekris L, Hampe CS, Obinu DA, Manconi A, Puddu L, Lynch K, Lernmark A. Epitope-restricted 65-kilodalton glutamic acid decarboxylase autoantibodies among new-onset Sardinian type 2 diabetes patients define phenotypes of autoimmune diabetes. The Journal of Clinical Endocrinology and Metabolism. 89: 5675-82. PMID 15531528 DOI: 10.1210/Jc.2004-0864  0.52
2004 Padmos RC, Bekris L, Knijff EM, Tiemeier H, Kupka RW, Cohen D, Nolen WA, Lernmark A, Drexhage HA. A high prevalence of organ-specific autoimmunity in patients with bipolar disorder. Biological Psychiatry. 56: 476-82. PMID 15450782 DOI: 10.1016/J.Biopsych.2004.07.003  0.52
2004 Luo D, Gilliam LK, Greenbaum C, Bekris L, Hampe CS, Daniels T, Richter W, Marcovina SM, Rolandsson O, Landin-Olsson M, Kockum I, Lernmark A. Conformation-dependent GAD65 autoantibodies in diabetes. Diabetologia. 47: 1581-91. PMID 15365614 DOI: 10.1007/S00125-004-1495-3  0.52
2003 Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, Bekris L, Cabellon J, Neve B, Vasseur-Delannoy V, Chikri M, Charles MA, Clement K, Lernmark A, Froguel P. GAD2 on chromosome 10p12 is a candidate gene for human obesity Plos Biology. 1. PMID 14691540 DOI: 10.1371/Journal.Pbio.0000068  0.52
2003 Niklasson B, Heller KE, Schønecker B, Bildsøe M, Daniels T, Hampe CS, Widlund P, Simonson WT, Schaefer JB, Rutledge E, Bekris L, Lindberg AM, Johansson S, Ortqvist E, Persson B, et al. Development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus. International Journal of Experimental Diabesity Research. 4: 35-44. PMID 12745669 DOI: 10.1080/15438600303733  0.52
2002 Mohatt J, Gilliam LK, Bekris L, Ebbesson S, Lernmark A. Type 1 diabetes-related autoantibodies are rare in Alaska native populations International Journal of Circumpolar Health. 61: 21-31. PMID 12002943 DOI: 10.3402/Ijch.V61I1.17402  0.52
2002 Maioli M, Tonolo G, Bekris L, Cirillo R, Schranz D, Cossu E, Ciccarese M, Lernmark A. GAD65 and IA-2 autoantibodies are common in a subset of siblings of Sardinian Type 2 diabetes families. Diabetes Research and Clinical Practice. 56: 41-7. PMID 11879720 DOI: 10.1016/S0168-8227(01)00348-5  0.52
2000 Hampe CS, Hammerle LP, Bekris L, Örtqvist E, Kockum I, Rolandsson O, Landin-Olsson M, Torn C, Persson B, Lernmark A. Recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes Journal of Clinical Endocrinology and Metabolism. 85: 4671-4679. PMID 11134126 DOI: 10.1210/Jcem.85.12.7070  0.52
2000 Novak EJ, Ortqvist E, Nord E, Edwall L, Hampe CS, Bekris L, Persson BE, Lernmark A. Stability of disease-associated antibody titers in pregnant women with type 1 diabetes with or without residual beta-cell function. Diabetes Care. 23: 1019-21. PMID 10895858 DOI: 10.2337/Diacare.23.7.1019  0.52
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