Year |
Citation |
Score |
2023 |
Shi C, Gottschalk WK, Colton CA, Mukherjee S, Lutz MW. Alzheimer's Disease Protein Relevance Analysis Using Human and Mouse Model Proteomics Data. Frontiers in Systems Biology. 3. PMID 37650081 DOI: 10.3389/fsysb.2023.1085577 |
0.315 |
|
2022 |
Whitson HE, Colton C, El Khoury J, Gate D, Goate A, Heneka MT, Kaddurah-Daouk R, Klein RS, Shinohara ML, Sisodia S, Spudich SS, Stevens B, Tanzi R, Ting JP, Garden G. Infection and inflammation: New perspectives on Alzheimer's disease. Brain, Behavior, & Immunity - Health. 22: 100462. PMID 36118272 DOI: 10.1016/j.bbih.2022.100462 |
0.323 |
|
2021 |
York A, Everhart A, Vitek MP, Gottschalk KW, Colton CA. Metabolism-Based Gene Differences in Neurons Expressing Hyperphosphorylated AT8- Positive (AT8+) Tau in Alzheimer's Disease. Asn Neuro. 13: 17590914211019443. PMID 34121475 DOI: 10.1177/17590914211019443 |
0.303 |
|
2021 |
Adams KJ, Wilson JG, Millington DS, Moseley MA, Colton CA, Thompson JW, Gottschalk WK. Capillary Electrophoresis-High Resolution Mass Spectrometry for Measuring In Vivo Arginine Isotope Incorporation in Alzheimer's Disease Mouse Models. Journal of the American Society For Mass Spectrometry. PMID 34028275 DOI: 10.1021/jasms.1c00055 |
0.305 |
|
2021 |
Bryan J, Mandan A, Kamat G, Gottschalk WK, Badea A, Adams KJ, Thompson JW, Colton CA, Mukherjee S, Lutz MW. Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480182 DOI: 10.1002/alz.12223 |
0.307 |
|
2019 |
Badea A, Delpratt NA, Anderson RJ, Dibb R, Qi Y, Wei H, Liu C, Wetsel WC, Avants BB, Colton C. Multivariate MR biomarkers better predict cognitive dysfunction in mouse models of Alzheimer's disease. Magnetic Resonance Imaging. PMID 30940494 DOI: 10.1016/J.Mri.2019.03.022 |
0.365 |
|
2015 |
Kan MJ, Lee JE, Wilson JG, Everhart AL, Brown CM, Hoofnagle AN, Jansen M, Vitek MP, Gunn MD, Colton CA. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5969-82. PMID 25878270 DOI: 10.1523/JNEUROSCI.4668-14.2015 |
0.426 |
|
2014 |
Hoos MD, Vitek MP, Ridnour LA, Wilson J, Jansen M, Everhart A, Wink DA, Colton CA. The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment. Molecular Neurodegeneration. 9: 50. PMID 25403885 DOI: 10.1186/1750-1326-9-50 |
0.307 |
|
2014 |
Colton CA, Wilson JG, Everhart A, Wilcock DM, Puoliväli J, Heikkinen T, Oksman J, Jääskeläinen O, Lehtimäki K, Laitinen T, Vartiainen N, Vitek MP. mNos2 deletion and human NOS2 replacement in Alzheimer disease models. Journal of Neuropathology and Experimental Neurology. 73: 752-69. PMID 25003233 DOI: 10.1097/NEN.0000000000000094 |
0.639 |
|
2013 |
Hoos MD, Richardson BM, Foster MW, Everhart A, Thompson JW, Moseley MA, Colton CA. Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase. Journal of Proteome Research. 12: 4462-77. PMID 24006891 DOI: 10.1021/Pr4005103 |
0.417 |
|
2012 |
Ridnour LA, Dhanapal S, Hoos M, Wilson J, Lee J, Cheng RY, Brueggemann EE, Hines HB, Wilcock DM, Vitek MP, Wink DA, Colton CA. Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1. Journal of Neurochemistry. 123: 736-49. PMID 23016931 DOI: 10.1111/Jnc.12028 |
0.561 |
|
2012 |
Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice. Journal of Alzheimer's Disease : Jad. 31: 359-69. PMID 22635103 DOI: 10.3233/JAD-2012-120421 |
0.37 |
|
2012 |
Sudduth TL, Wilson JG, Everhart A, Colton CA, Wilcock DM. Lithium treatment of APPSwDI/NOS2-/- mice leads to reduced hyperphosphorylated tau, increased amyloid deposition and altered inflammatory phenotype. Plos One. 7: e31993. PMID 22347510 DOI: 10.1371/journal.pone.0031993 |
0.618 |
|
2012 |
Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-Degenerative Diseases. 10: 122-6. PMID 22326991 DOI: 10.1159/000334914 |
0.631 |
|
2011 |
Wilcock DM, Zhao Q, Morgan D, Gordon MN, Everhart A, Wilson JG, Lee JE, Colton CA. Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses. Asn Neuro. 3: 249-58. PMID 21995345 DOI: 10.1042/An20110018 |
0.719 |
|
2011 |
Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, et al. Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies. Alzheimer's Research & Therapy. 3: 28. PMID 21943025 DOI: 10.1186/Alzrt90 |
0.574 |
|
2011 |
Wilcock DM, Morgan D, Gordon MN, Taylor TL, Ridnour LA, Wink DA, Colton CA. Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence. Journal of Neuroinflammation. 8: 115. PMID 21906275 DOI: 10.1186/1742-2094-8-115 |
0.683 |
|
2011 |
Wilcock DM, Colton CA. Anti-amyloid-β immunotherapy in Alzheimer's disease: Relevance of transgenic mouse studies to clinical trials Advances in Alzheimer's Disease. 1: 247-261. DOI: 10.3233/978-1-60750-733-8-247 |
0.354 |
|
2010 |
Van Nostrand WE, Xu F, Rozemuller AJ, Colton CA. Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2. Stroke; a Journal of Cerebral Circulation. 41: S135-8. PMID 20876489 DOI: 10.1161/STROKEAHA.110.595272 |
0.327 |
|
2010 |
Colton C, Wilcock DM. Assessing activation states in microglia. Cns & Neurological Disorders Drug Targets. 9: 174-91. PMID 20205642 |
0.567 |
|
2010 |
Wu J, Yoo S, Wilcock D, Lytle JM, Leung PY, Colton CA, Wrathall JR. Interaction of NG2(+) glial progenitors and microglia/macrophages from the injured spinal cord. Glia. 58: 410-22. PMID 19780197 DOI: 10.1002/Glia.20932 |
0.481 |
|
2010 |
Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease (The Journal of Neuroscience (2009) (7957-7965)) Journal of Neuroscience. 30: 1197-1198. |
0.328 |
|
2009 |
Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7957-65. PMID 19553436 DOI: 10.1523/JNEUROSCI.1339-09.2009 |
0.619 |
|
2009 |
Wilcock DM, Vitek MP, Colton CA. Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. Neuroscience. 159: 1055-69. PMID 19356689 DOI: 10.1016/j.neuroscience.2009.01.023 |
0.603 |
|
2009 |
Wilcock DM, Colton CA. Immunotherapy, vascular pathology, and microhemorrhages in transgenic mice. Cns & Neurological Disorders Drug Targets. 8: 50-64. PMID 19275636 DOI: 10.2174/187152709787601858 |
0.624 |
|
2009 |
Vitek MP, Brown CM, Colton CA. APOE genotype-specific differences in the innate immune response. Neurobiology of Aging. 30: 1350-60. PMID 18155324 DOI: 10.1016/j.neurobiolaging.2007.11.014 |
0.322 |
|
2009 |
Vitek MP, Christensen DJ, Wilcock D, Oddo J, Gharkholonarehe N, Ohkubo N, Toku K, Van Nostrand WE, Li F, Colton CA. O2-04-05: Novel mechanism where ApoE mimetics activate PP2A activity and reduce Alzheimer's pathology in three different transgenic models Alzheimer's & Dementia. 5: P111-P111. DOI: 10.1016/j.jalz.2009.05.347 |
0.56 |
|
2009 |
Colton CA, Vitek MP, Wilcock D. O1-03-04: Testing the amyloid cascade hypothesis in a novel mouse model of Alzheimer's disease that shows complete disease progression Alzheimer's & Dementia. 5: P82-P83. DOI: 10.1016/j.jalz.2009.05.208 |
0.572 |
|
2008 |
Colton CA, Wilcock DM, Wink DA, Davis J, Van Nostrand WE, Vitek MP. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. Journal of Alzheimer's Disease : Jad. 15: 571-87. PMID 19096157 DOI: 10.3233/Jad-2008-15405 |
0.662 |
|
2008 |
Wilcock DM, Colton CA. Anti-amyloid-beta immunotherapy in Alzheimer's disease: relevance of transgenic mouse studies to clinical trials. Journal of Alzheimer's Disease : Jad. 15: 555-69. PMID 19096156 |
0.606 |
|
2008 |
Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5312-20. PMID 18480287 DOI: 10.1523/JNEUROSCI.1042-08.2008 |
0.355 |
|
2008 |
Wilcock DM, Lewis MR, Van Nostrand WE, Davis J, Previti ML, Gharkholonarehe N, Vitek MP, Colton CA. Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1537-45. PMID 18272675 DOI: 10.1523/JNEUROSCI.5066-07.2008 |
0.642 |
|
2008 |
Brown CM, Choi E, Xu Q, Vitek MP, Colton CA. The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol. Neurobiology of Aging. 29: 1783-94. PMID 17553597 DOI: 10.1016/j.neurobiolaging.2007.04.018 |
0.32 |
|
2008 |
Colton CA, Wilcock DM, Davis J, Van Nostrand W, Vitek MP. P1-050: Progression to a full spectrum of Alzheimer's-like pathology in animal models of amyloid deposition by reduction in NOS2 Alzheimer's & Dementia. 4: T220-T220. DOI: 10.1016/j.jalz.2008.05.635 |
0.577 |
|
2008 |
Wilcock DM, Vitek MP, Colton CA. P4-291: Cerebral amyloid angiopathy results in neurovascular unit disruption in transgenic mouse models of Alzheimer's disease Alzheimer's & Dementia. 4: T756-T757. DOI: 10.1016/j.jalz.2008.05.2360 |
0.595 |
|
2007 |
Brown CM, Xu Q, Okhubo N, Vitek MP, Colton CA. Androgen-mediated immune function is altered by the apolipoprotein E gene. Endocrinology. 148: 3383-90. PMID 17395708 DOI: 10.1210/en.2006-1200 |
0.338 |
|
2006 |
Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, Vitek MP. Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation. 3: 27. PMID 17005052 DOI: 10.1186/1742-2094-3-27 |
0.377 |
|
2006 |
Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Weinberg B, Dawson H. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 12867-72. PMID 16908860 DOI: 10.1073/pnas.0601075103 |
0.363 |
|
2006 |
Colton C, Wink D, Weinberg JB, Nostrand WV, Dawson H, Vitek M. O29. Nitric oxide is neuroprotective in a mouse model of Aβ-mediated chronic neurodegeneration Nitric Oxide. 14: 9. DOI: 10.1016/J.Niox.2006.04.033 |
0.374 |
|
2004 |
Colton CA, Needham LK, Brown C, Cook D, Rasheed K, Burke JR, Strittmatter WJ, Schmechel DE, Vitek MP. APOE genotype-specific differences in human and mouse macrophage nitric oxide production. Journal of Neuroimmunology. 147: 62-7. PMID 14741429 DOI: 10.1016/J.Jneuroim.2003.10.015 |
0.402 |
|
2003 |
Czapiga M, Colton CA. Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport. Journal of Neuroimmunology. 134: 44-51. PMID 12507771 DOI: 10.1016/S0165-5728(02)00394-6 |
0.706 |
|
2002 |
Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. Neurobiology of Aging. 23: 777-85. PMID 12392781 DOI: 10.1016/S0197-4580(02)00016-7 |
0.735 |
|
2002 |
Colton CA, Brown CM, Czapiga M, Vitek MP. Apolipoprotein-E allele-specific regulation of nitric oxide production. Annals of the New York Academy of Sciences. 962: 212-25. PMID 12076977 DOI: 10.1111/J.1749-6632.2002.Tb04070.X |
0.734 |
|
2002 |
Brown CM, Wright E, Colton CA, Sullivan PM, Laskowitz DT, Vitek MP. Apolipoprotein E isoform mediated regulation of nitric oxide release. Free Radical Biology & Medicine. 32: 1071-5. PMID 12031891 DOI: 10.1016/S0891-5849(02)00803-1 |
0.371 |
|
2001 |
Wink DA, Miranda KM, Espey MG, Pluta RM, Hewett SJ, Colton C, Vitek M, Feelisch M, Grisham MB. Mechanisms of the antioxidant effects of nitric oxide. Antioxidants & Redox Signaling. 3: 203-13. PMID 11396476 DOI: 10.1089/152308601300185179 |
0.302 |
|
2001 |
Colton CA, Czapiga M, Snell-Callanan J, Chernyshev ON, Vitek MP. Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport. Biochimica Et Biophysica Acta. 1535: 134-44. PMID 11342002 DOI: 10.1016/S0925-4439(00)00092-2 |
0.7 |
|
2000 |
Colton CA, Chernyshev ON, Gilbert DL, Vitek MP. Microglial contribution to oxidative stress in Alzheimer's disease Annals of the New York Academy of Sciences. 899: 292-307. PMID 10863548 |
0.343 |
|
2000 |
Colton CA, Czapiga M, Chernyshev ON, Vitek MP. The APoE4 allele is associated with enhanced nitric oxide production and enhanced arginine transport Neurobiology of Aging. 21: 254-255. DOI: 10.1016/S0197-4580(00)83095-X |
0.664 |
|
1999 |
Czapiga M, Colton CA. Function of microglia in organotypic slice cultures. Journal of Neuroscience Research. 56: 644-51. PMID 10374819 DOI: 10.1002/(Sici)1097-4547(19990615)56:6<644::Aid-Jnr10>3.0.Co;2-9 |
0.665 |
|
1997 |
Vitek MP, Snell J, Dawson H, Colton CA. Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide Biochemical and Biophysical Research Communications. 240: 391-394. PMID 9388488 DOI: 10.1006/bbrc.1997.7408 |
0.398 |
|
1996 |
Colton C, Wilt S, Gilbert D, Chernyshev O, Snell J, Dubois-Dalcq M. Species differences in the generation of reactive oxygen species by microglia Molecular and Chemical Neuropathology. 28: 15-20. PMID 8871937 DOI: 10.1007/Bf02815200 |
0.386 |
|
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