| Year |
Citation |
Score |
| 2020 |
Kasap M, Dwyer DS. Clozapine, nimodipine and endosulfan differentially suppress behavioral defects caused by gain-of-function mutations in a two-pore domain K channel (UNC-58). Neuroscience Research. PMID 32681854 DOI: 10.1016/J.Neures.2020.07.006 |
0.32 |
|
| 2019 |
Kasap M, Aamodt EJ, Sagrera CE, Dwyer DS. Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel. Behavioural Pharmacology. PMID 31850963 DOI: 10.1097/Fbp.0000000000000526 |
0.346 |
|
| 2019 |
Tian X, Richard A, El-Saadi MW, Bhandari A, Latimer B, Van Savage I, Holmes K, Klein RL, Dwyer D, Goeders NE, Yang XW, Lu XH. Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model. Molecular Psychiatry. PMID 31444475 DOI: 10.1038/S41380-019-0492-3 |
0.522 |
|
| 2014 |
Dwyer DS, Aamodt E, Cohen B, Buttner EA. Drug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs. Frontiers in Pharmacology. 5: 177. PMID 25120487 DOI: 10.3389/Fphar.2014.00177 |
0.388 |
|
| 2013 |
Dwyer DS, Aamodt EJ. Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation. Plos One. 8: e63851. PMID 23700438 DOI: 10.1371/Journal.Pone.0063851 |
0.303 |
|
| 2011 |
Weeks KR, Dwyer DS, Aamodt EJ. Clozapine and lithium require Caenorhabditis elegans β-arrestin and serum- and glucocorticoid-inducible kinase to affect Daf-16 (FOXO) localization. Journal of Neuroscience Research. 89: 1658-65. PMID 21732403 DOI: 10.1002/Jnr.22705 |
0.311 |
|
| 2010 |
Weeks KR, Dwyer DS, Aamodt EJ. Antipsychotic drugs activate the C. elegans akt pathway via the DAF-2 insulin/IGF-1 receptor. Acs Chemical Neuroscience. 1: 463-73. PMID 22778838 DOI: 10.1021/Cn100010P |
0.384 |
|
| 2009 |
Williams B, Dwyer DS. Structure-based discovery of low molecular weight compounds that stimulate neurite outgrowth and substitute for nerve growth factor. Journal of Neurochemistry. 110: 1876-84. PMID 19627449 DOI: 10.1111/J.1471-4159.2009.06291.X |
0.302 |
|
| 2009 |
Donohoe DR, Jarvis RA, Weeks K, Aamodt EJ, Dwyer DS. Behavioral adaptation in C. elegans produced by antipsychotic drugs requires serotonin and is associated with calcium signaling and calcineurin inhibition. Neuroscience Research. 64: 280-9. PMID 19447297 DOI: 10.1016/J.Neures.2009.03.012 |
0.377 |
|
| 2008 |
Dwyer DS, Weeks K, Aamodt EJ. Drug discovery based on genetic and metabolic findings in schizophrenia. Expert Review of Clinical Pharmacology. 1: 773-89. PMID 24410607 DOI: 10.1586/17512433.1.6.773 |
0.375 |
|
| 2008 |
Lieberman JA, Bymaster FP, Meltzer HY, Deutch AY, Duncan GE, Marx CE, Aprille JR, Dwyer DS, Li XM, Mahadik SP, Duman RS, Porter JH, Modica-Napolitano JS, Newton SS, Csernansky JG. Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection. Pharmacological Reviews. 60: 358-403. PMID 18922967 DOI: 10.1124/Pr.107.00107 |
0.359 |
|
| 2008 |
Simpson IA, Dwyer D, Malide D, Moley KH, Travis A, Vannucci SJ. The facilitative glucose transporter GLUT3: 20 years of distinction. American Journal of Physiology. Endocrinology and Metabolism. 295: E242-53. PMID 18577699 DOI: 10.1152/Ajpendo.90388.2008 |
0.474 |
|
| 2008 |
Donohoe DR, Weeks K, Aamodt EJ, Dwyer DS. Antipsychotic drugs alter neuronal development including ALM neuroblast migration and PLM axonal outgrowth in Caenorhabditis elegans. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 26: 371-80. PMID 18282677 DOI: 10.1016/J.Ijdevneu.2007.08.021 |
0.337 |
|
| 2007 |
Dwyer DS, Dickson A. Neuroprotection and enhancement of neurite outgrowth with small molecular weight compounds from screens of chemical libraries. International Review of Neurobiology. 77: 247-89. PMID 17178477 DOI: 10.1016/S0074-7742(06)77008-8 |
0.331 |
|
| 2006 |
Donohoe DR, Aamodt EJ, Osborn E, Dwyer DS. Antipsychotic drugs disrupt normal development in Caenorhabditis elegans via additional mechanisms besides dopamine and serotonin receptors. Pharmacological Research. 54: 361-72. PMID 16962336 DOI: 10.1016/J.Phrs.2006.07.002 |
0.399 |
|
| 2006 |
Arulmozhi DK, Dwyer DS, Bodhankar SL. Antipsychotic induced metabolic abnormalities: An interaction study with various PPAR modulators in mice Life Sciences. 79: 1865-1872. PMID 16828808 DOI: 10.1016/J.Lfs.2006.06.016 |
0.397 |
|
| 2005 |
Dwyer DS, Donohoe D, Lu XH, Aamodt EJ. Mechanistic connections between glucose/lipid disturbances and weight gain induced by antipsychotic drugs. International Review of Neurobiology. 65: 211-47. PMID 16140058 DOI: 10.1016/S0074-7742(04)65008-2 |
0.598 |
|
| 2005 |
Lu XH, Dwyer DS. Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways. Journal of Molecular Neuroscience : Mn. 27: 43-64. PMID 16055946 DOI: 10.1385/Jmn:27:1:043 |
0.573 |
|
| 2004 |
Lu XH, Bradley RJ, Dwyer DS. Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38. Brain Research. 1011: 58-68. PMID 15140644 DOI: 10.1016/J.Brainres.2004.03.018 |
0.52 |
|
| 2003 |
Dwyer DS, Lu XH, Iii AM. Neuronal glucose metabolism and schizophrenia: therapeutic prospects? Expert Review of Neurotherapeutics. 3: 29-40. PMID 19810845 DOI: 10.1586/14737175.3.1.29 |
0.578 |
|
| 2003 |
Dwyer DS, Donohoe D. Induction of hyperglycemia in mice with atypical antipsychotic drugs that inhibit glucose uptake. Pharmacology, Biochemistry, and Behavior. 75: 255-60. PMID 12873613 DOI: 10.1016/S0091-3057(03)00079-0 |
0.504 |
|
| 2003 |
Dwyer DS, Lu XH, Bradley RJ. Cytotoxicity of conventional and atypical antipsychotic drugs in relation to glucose metabolism. Brain Research. 971: 31-9. PMID 12691834 DOI: 10.1016/S0006-8993(03)02351-5 |
0.653 |
|
| 2003 |
Dwyer DS, Ardizzone TD. Mimicry of dimerization by synthetic peptides designed to target homologous regions of proteins. Proteomics. 3: 317-24. PMID 12627385 DOI: 10.1002/pmic.200390045 |
0.676 |
|
| 2002 |
Dwyer DS, Ardizzone TD, Bradley RJ. Psychoactive drugs affect glucose transport and the regulation of glucose metabolism. International Review of Neurobiology. 51: 503-30. PMID 12420369 DOI: 10.1016/S0074-7742(02)51015-1 |
0.73 |
|
| 2002 |
Dwyer DS, Vannucci SJ, Simpson IA. Expression, regulation, and functional role of glucose transporters (GLUTs) in brain. International Review of Neurobiology. 51: 159-88. PMID 12420359 DOI: 10.1016/S0074-7742(02)51005-9 |
0.47 |
|
| 2002 |
Ardizzone TD, Lu XH, Dwyer DS. Calcium-independent inhibition of glucose transport in PC-12 and L6 cells by calcium channel antagonists. American Journal of Physiology. Cell Physiology. 283: C579-86. PMID 12107068 DOI: 10.1152/Ajpcell.00451.2001 |
0.699 |
|
| 2001 |
Ardizzone TD, Bradley RJ, Freeman AM, Dwyer DS. Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine. Brain Research. 923: 82-90. PMID 11743975 DOI: 10.1016/S0006-8993(01)03026-8 |
0.746 |
|
| 2001 |
Dwyer DS, Bradley RJ, Kablinger AS, Freeman AM. Glucose metabolism in relation to schizophrenia and antipsychotic drug treatment Annals of Clinical Psychiatry. 13: 103-113. PMID 11534925 DOI: 10.1023/A:1016671725396 |
0.475 |
|
| 2001 |
Dwyer DS. Model of the 3-D structure of the GLUT3 glucose transporter and molecular dynamics simulation of glucose transport Proteins: Structure, Function and Genetics. 42: 531-541. PMID 11170207 DOI: 10.1002/1097-0134(20010301)42:4<531::Aid-Prot110>3.0.Co;2-9 |
0.438 |
|
| 1999 |
Pinkofsky HB, Dwyer DS, Bradley RJ. The inhibition of GLUT1 glucose transport and cytochalasin B binding activity by tricyclic antidepressants Life Sciences. 66: 271-278. PMID 10666003 DOI: 10.1016/S0024-3205(99)00590-1 |
0.512 |
|
| 1999 |
Dwyer DS, Liu Y, Bradley RJ. Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells Neuroscience Letters. 274: 151-154. PMID 10548412 DOI: 10.1016/S0304-3940(99)00712-0 |
0.513 |
|
| 1999 |
Dwyer DS, Pinkofsky HB, Ye L, Bradley RJ. Antipsychotic drugs affect glucose uptake and the expression of glucose transporters in PC12 cells Progress in Neuro-Psychopharmacology and Biological Psychiatry. 23: 69-80. PMID 10368857 DOI: 10.1016/S0278-5846(98)00092-X |
0.445 |
|
| 1999 |
Dwyer D, Bradley R, Kablinger A, Freeman A. Blockade of glucose transporters by antipsychotic drugs European Neuropsychopharmacology. 9: 256-257. DOI: 10.1016/S0924-977X(99)80254-5 |
0.422 |
|
| 1998 |
Dwyer DS, Pinkofsky HB, Liu Y, Bradley RJ. Attachment of PC12 cells to adhesion substratum induces the accumulation of glucose transporters (GLUTs) and stimulates glucose metabolism Neurochemical Research. 23: 1107-1116. PMID 9704601 DOI: 10.1023/A:1020768321358 |
0.35 |
|
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