Karen Ocorr, PhD - Publications

Affiliations: 
Sanford-Burnham Medical Research Institute, USA 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Romero MR, Diop SB, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy. Biorxiv : the Preprint Server For Biology. PMID 37873259 DOI: 10.1101/2023.10.02.560407  0.382
2023 Birker K, Ge S, Kirkland NJ, Theis JL, Marchant J, Fogarty ZC, Missinato MA, Kalvakuri S, Grossfeld P, Engler AJ, Ocorr K, Nelson TJ, Colas AR, Olson TM, Vogler G, et al. Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity. Elife. 12. PMID 37404133 DOI: 10.7554/eLife.83385  0.309
2023 Ren J, Zeng Q, Wu H, Liu X, Guida MC, Huang W, Zhai Y, Li J, Ocorr K, Bodmer R, Tang M. Deacetylase-dependent and -independent role of HDAC3 in cardiomyopathy. Journal of Cellular Physiology. PMID 36745702 DOI: 10.1002/jcp.30957  0.35
2022 Saha S, Spinelli L, Castro Mondragon JA, Kervadec A, Lynott M, Kremmer L, Roder L, Krifa S, Torres M, Brun C, Vogler G, Bodmer R, Colas AR, Ocorr K, Perrin L. Genetic architecture of natural variation of cardiac performance from flies to humans. Elife. 11. PMID 36383075 DOI: 10.7554/eLife.82459  0.308
2020 Walls S, Diop S, Birse R, Elmen L, Gan Z, Kalvakuri S, Pineda S, Reddy C, Taylor E, Trinh B, Vogler G, Zarndt R, McCulloch A, Lee P, Bhattacharya S, ... ... Ocorr K, et al. Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila. Cell Reports. 108445. PMID 33242407 DOI: 10.1016/j.celrep.2020.108445  0.33
2020 Walls SM, Chatfield DA, Ocorr K, Harris GL, Bodmer R. Systemic and heart autonomous effects of sphingosine Δ-4 desaturase deficiency in lipotoxic cardiac pathophysiology. Disease Models & Mechanisms. PMID 32641420 DOI: 10.1242/dmm.043083  0.385
2020 Akasaka T, Ocorr K, Lin L, Vogler G, Bodmer R, Grossfeld P. Overexpression of in the Developing Heart Causes Valvar and Contractility Defects: Implications for Human Congenital Heart Disease. Journal of Cardiovascular Development and Disease. 7. PMID 32498427 DOI: 10.3390/jcdd7020022  0.318
2020 Elmén L, Volpato CB, Kervadec A, Pineda S, Kalvakuri S, Alayari NN, Foco L, Pramstaller PP, Ocorr K, Rossini A, Cammarato A, Colas AR, Hicks AA, Bodmer R. Silencing of CCR4-NOT complex subunits affect heart structure and function. Disease Models & Mechanisms. PMID 32471864 DOI: 10.1242/Dmm.044727  0.316
2019 Chang K, Kang P, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H. TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2. Autophagy. 1-16. PMID 31884871 DOI: 10.1080/15548627.2019.1704117  0.331
2018 Walls SM, Cammarato A, Chatfield DA, Ocorr K, Harris GL, Bodmer R. Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy. Cell Reports. 22: 2702-2715. PMID 29514098 DOI: 10.1016/j.celrep.2018.02.034  0.304
2016 Hartley PS, Motamedchaboki K, Bodmer R, Ocorr K. SPARC-Dependent Cardiomyopathy in Drosophila. Circulation. Cardiovascular Genetics. PMID 26839388 DOI: 10.1161/CIRCGENETICS.115.001254  0.365
2015 Zarndt R, Piloto S, Powell FL, Haddad GG, Bodmer R, Ocorr K. Cardiac responses to hypoxia and reoxygenation in Drosophila. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00164.2015. PMID 26377557 DOI: 10.1152/Ajpregu.00164.2015  0.319
2015 Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, Fuhrmann A, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, et al. Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart. Science Translational Medicine. 7: 292ra99. PMID 26084806 DOI: 10.1126/Scitranslmed.Aaa5843  0.333
2015 Martínez-Morentin L, Martínez L, Piloto S, Yang H, Schon EA, Garesse R, Bodmer R, Ocorr K, Cervera M, Arredondo JJ. Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model. Human Molecular Genetics. 24: 3608-22. PMID 25792727 DOI: 10.1093/Hmg/Ddv106  0.327
2015 Cammarato A, Ocorr S, Ocorr K. Enhanced assessment of contractile dynamics in Drosophila hearts. Biotechniques. 58: 77-80. PMID 25652030 DOI: 10.2144/000114255  0.334
2014 Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K, Melkani GC. Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. Rare Diseases (Austin, Tex.). 2: e968003. PMID 26942103 DOI: 10.4161/2167549X.2014.968003  0.3
2014 Ocorr K, Vogler G, Bodmer R. Methods to assess Drosophila heart development, function and aging. Methods (San Diego, Calif.). 68: 265-72. PMID 24727147 DOI: 10.1016/j.ymeth.2014.03.031  0.342
2014 Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 13: 431-40. PMID 24400780 DOI: 10.1111/Acel.12193  0.347
2014 Tang M, Yuan W, Bodmer R, Wu X, Ocorr K. The role of pygopus in the differentiation of intracardiac valves in Drosophila. Genesis (New York, N.Y. : 2000). 52: 19-28. PMID 24265259 DOI: 10.1002/dvg.22724  0.316
2013 Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K. Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. Plos Genetics. 9: e1004024. PMID 24367279 DOI: 10.1371/Journal.Pgen.1004024  0.31
2013 Tang M, Yuan W, Fan X, Liu M, Bodmer R, Ocorr K, Wu X. Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling. Circulation. Cardiovascular Genetics. 6: 472-80. PMID 24046329 DOI: 10.1161/CIRCGENETICS.113.000253  0.318
2013 Zhang R, Han P, Yang H, Ouyang K, Lee D, Lin YF, Ocorr K, Kang G, Chen J, Stainier DY, Yelon D, Chi NC. In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498: 497-501. PMID 23783515 DOI: 10.1038/Nature12322  0.365
2012 Melkani GC, Bodmer R, Ocorr K, Bernstein SI. Exploration and Suppression of Cardiac Amyloidosis Induced by Huntington's Disease-Causing Amyloid in the Drosophila Heart Model Biophysical Journal. 102: 351a. DOI: 10.1016/J.Bpj.2011.11.1923  0.367
2011 Melkani GC, Bodmer R, Ocorr K, Bernstein SI. The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. Plos One. 6: e22579. PMID 21799905 DOI: 10.1371/Journal.Pone.0022579  0.4
2011 Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, ... ... Ocorr K, et al. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of Cell Biology. 193: 1181-96. PMID 21690310 DOI: 10.1083/Jcb.201006114  0.317
2011 Lim HY, Wang W, Wessells RJ, Ocorr K, Bodmer R. Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes & Development. 25: 189-200. PMID 21245170 DOI: 10.1101/Gad.1992411  0.368
2011 Nishimura M, Ocorr K, Bodmer R, Cartry J. Drosophila as a model to study cardiac aging. Experimental Gerontology. 46: 326-30. PMID 21130861 DOI: 10.1016/j.exger.2010.11.035  0.342
2011 Melkani GC, Ocorr K, Bodmer R, Bernstein SI. Drosophila as a Model for Amyloid Induced Cardiac Dysfunction Biophysical Journal. 100: 294a. DOI: 10.1016/J.Bpj.2010.12.1806  0.358
2010 Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia CP, ... ... Ocorr K, et al. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell. 141: 142-53. PMID 20371351 DOI: 10.1016/J.Cell.2010.02.023  0.35
2010 Melkani GC, Ocorr K, Bodmer R, Bernstein SI. UNC-45 Knock-Down in Drosophila Heart Targets Myosin Accumulation and Yields Severe Myofibrillar Disarray and Cardiac Dysfunction Biophysical Journal. 98: 7a. DOI: 10.1016/J.Bpj.2009.12.041  0.364
2009 Vogler G, Ocorr K. Visualizing the beating heart in Drosophila. Journal of Visualized Experiments : Jove. PMID 19786947 DOI: 10.3791/1425  0.301
2009 Akasaka T, Ocorr K. Drug discovery through functional screening in the Drosophila heart. Methods in Molecular Biology (Clifton, N.J.). 577: 235-49. PMID 19718521 DOI: 10.1007/978-1-60761-232-2_18  0.321
2009 Wessells R, Fitzgerald E, Piazza N, Ocorr K, Morley S, Davies C, Lim HY, Elmén L, Hayes M, Oldham S, Bodmer R. d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell. 8: 542-52. PMID 19594484 DOI: 10.1111/j.1474-9726.2009.00504.x  0.303
2009 Fink M, Callol-Massot C, Chu A, Ruiz-Lozano P, Izpisua Belmonte JC, Giles W, Bodmer R, Ocorr K. A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. Biotechniques. 46: 101-13. PMID 19317655 DOI: 10.2144/000113078  0.36
2009 Buechling T, Akasaka T, Vogler G, Ruiz-Lozano P, Ocorr K, Bodmer R. Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. Developmental Biology. 328: 483-92. PMID 19233157 DOI: 10.1016/j.ydbio.2009.02.013  0.331
2009 Cammarato A, Alayari NN, Ocorr K, Bodmer R, Bernstein SI. Polygenic Modulation of Cardiac Dysfunction in Drosophila Assessed by High-speed Video Imaging, Motion Detection Analysis and Fluorescent Microscopy Biophysical Journal. 96: 622a. DOI: 10.1016/J.Bpj.2008.12.3288  0.319
2008 Qian L, Mohapatra B, Akasaka T, Liu J, Ocorr K, Towbin JA, Bodmer R. Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 19833-8. PMID 19074289 DOI: 10.1073/pnas.0808705105  0.349
2008 Taghli-Lamallem O, Akasaka T, Hogg G, Nudel U, Yaffe D, Chamberlain JS, Ocorr K, Bodmer R. Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. Aging Cell. 7: 237-49. PMID 18221418 DOI: 10.1111/j.1474-9726.2008.00367.x  0.37
2008 Mery A, Taghli-Lamallem O, Clark KA, Beckerle MC, Wu X, Ocorr K, Bodmer R. The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. The Journal of Experimental Biology. 211: 15-23. PMID 18083727 DOI: 10.1242/jeb.012435  0.361
2007 Ocorr KA, Crawley T, Gibson G, Bodmer R. Genetic variation for cardiac dysfunction in Drosophila. Plos One. 2: e601. PMID 17622346 DOI: 10.1371/journal.pone.0000601  0.354
2007 Ocorr K, Perrin L, Lim HY, Qian L, Wu X, Bodmer R. Genetic control of heart function and aging in Drosophila. Trends in Cardiovascular Medicine. 17: 177-82. PMID 17574126 DOI: 10.1016/j.tcm.2007.04.001  0.334
2007 Ocorr K, Akasaka T, Bodmer R. Age-related cardiac disease model of Drosophila. Mechanisms of Ageing and Development. 128: 112-6. PMID 17125816 DOI: 10.1016/j.mad.2006.11.023  0.328
2006 Akasaka T, Klinedinst S, Ocorr K, Bustamante EL, Kim SK, Bodmer R. The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proceedings of the National Academy of Sciences of the United States of America. 103: 11999-2004. PMID 16882722 DOI: 10.1073/pnas.0603098103  0.327
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