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Gaurav Sahay, Ph.D. - Publications

Affiliations: 
2009 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacy
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Herrera-Barrera M, Gautam M, Lokras A, Vlasova K, Foged C, Sahay G. Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors. The Aaps Journal. 25: 65. PMID 37380935 DOI: 10.1208/s12248-023-00833-2  0.319
2023 Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, ... ... Sahay G, et al. NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Reports. 42: 112372. PMID 37086404 DOI: 10.1016/j.celrep.2023.112372  0.454
2022 Henderson MI, Eygeris Y, Jozic A, Herrera M, Sahay G. Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles. Molecular Pharmaceutics. PMID 36129254 DOI: 10.1021/acs.molpharmaceut.2c00587  0.678
2021 Herrera M, Kim J, Eygeris Y, Jozic A, Sahay G. Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. Biomaterials Science. PMID 33586742 DOI: 10.1039/d0bm01947j  0.32
2020 Mukherjee A, MacDonald KD, Kim J, Henderson MI, Eygeris Y, Sahay G. Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models. Science Advances. 6. PMID 33208364 DOI: 10.1126/sciadv.abc5911  0.644
2020 Kim J, Jozic A, Sahay G. Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery. Cellular and Molecular Bioengineering. 1-12. PMID 32837581 DOI: 10.1007/S12195-020-00619-Y  0.408
2020 Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith JP, Hou S, Esposito AA, Ketova T, Welsher K, Joyal JL, Almarsson Ö, Sahay G. Author Correction: Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA. Nature Communications. 11: 3435. PMID 32632117 DOI: 10.1038/S41467-020-17025-7  0.358
2020 Eygeris Y, Patel S, Jozic A, Sahay G. Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery. Nano Letters. PMID 32375002 DOI: 10.1021/Acs.Nanolett.0C01386  0.355
2020 Patel S, Ashwanikumar N, Robinson E, Xia Y, Mihai C, Griffith JP, Hou S, Esposito AA, Ketova T, Welsher K, Joyal JL, Almarsson Ö, Sahay G. Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA. Nature Communications. 11: 983. PMID 32080183 DOI: 10.1038/S41467-020-14527-2  0.418
2019 Rosch JG, Winter H, DuRoss AN, Sahay G, Sun C. Inverse-micelle synthesis of doxorubicin-loaded alginate/chitosan nanoparticles and assessment of breast cancer cytotoxicity. Colloid and Interface Science Communications. 28: 69-74. PMID 31602357 DOI: 10.1016/J.Colcom.2018.12.002  0.39
2019 Patel S, Kim J, Herrera M, Mukherjee A, Kabanov A, Sahay G. Brief update on endocytosis of nanomedicines. Advanced Drug Delivery Reviews. PMID 31419450 DOI: 10.1016/J.Addr.2019.08.004  0.596
2019 Kim J, Narayana A, Patel S, Sahay G. Advances in intracellular delivery through supramolecular self-assembly of oligonucleotides and peptides. Theranostics. 9: 3191-3212. PMID 31244949 DOI: 10.7150/Thno.33921  0.34
2019 Patel S, Ryals RC, Weller KK, Pennesi ME, Sahay G. Lipid nanoparticles for delivery of messenger RNA to the back of the eye. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30986436 DOI: 10.1016/J.Jconrel.2019.04.015  0.378
2019 Lübtow MM, Nelke LC, Seifert J, Kühnemundt J, Sahay G, Dandekar G, Nietzer SL, Luxenhofer R. Drug induced micellization into ultra-high capacity and stable curcumin nanoformulations: Physico-chemical characterization and evaluation in 2D and 3D in vitro models. Journal of Controlled Release : Official Journal of the Controlled Release Society. 303: 162-180. PMID 30981815 DOI: 10.1016/J.Jconrel.2019.04.014  0.322
2019 Duross A, Neufeld MJ, Landry MR, Rosch J, Eaton CT, Sahay G, Thomas CR, Sun C. Micellar Formulation of Talazoparib and Buparlisib for Enhanced DNA Damage in Breast Cancer Chemoradiotherapy. Acs Applied Materials & Interfaces. PMID 30860347 DOI: 10.1021/Acsami.9B02408  0.309
2018 Rosch JG, Brown AL, DuRoss AN, DuRoss EL, Sahay G, Sun C. Nanoalginates via Inverse-Micelle Synthesis: Doxorubicin-Encapsulation and Breast Cancer Cytotoxicity. Nanoscale Research Letters. 13: 350. PMID 30392055 DOI: 10.1186/S11671-018-2748-2  0.397
2018 Brown AL, Winter H, Goforth AM, Sahay G, Sun C. Facile Synthesis of Ligand-Free Iridium Nanoparticles and Their In Vitro Biocompatibility. Nanoscale Research Letters. 13: 208. PMID 30006748 DOI: 10.1186/S11671-018-2621-3  0.38
2018 Robinson E, MacDonald KD, Slaughter K, McKinney M, Patel S, Sun C, Sahay G. Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29910178 DOI: 10.1016/J.Ymthe.2018.05.014  0.394
2018 Brown AL, Kai MP, DuRoss AN, Sahay G, Sun C. Biodistribution and Toxicity of Micellar Platinum Nanoparticles in Mice via Intravenous Administration. Nanomaterials (Basel, Switzerland). 8. PMID 29875350 DOI: 10.3390/Nano8060410  0.384
2018 Patel S, Athirasala A, Dos Passos Menezes P, Ashwanikumar N, Zou T, Sahay G, Bertassoni L. Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications. Tissue Engineering. Part A. PMID 29661055 DOI: 10.1089/Ten.Tea.2017.0444  0.347
2018 Ashwanikumar N, Plaut JS, Mostofian B, Patel S, Kwak P, Sun C, McPhail K, Zuckerman DM, Esener SC, Sahay G. Supramolecular self assembly of nanodrill-like structures for intracellular delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29501722 DOI: 10.1016/J.Jconrel.2018.02.041  0.354
2017 Patel S, Ashwanikumar N, Robinson E, DuRoss A, Sun C, Murphy-Benenato KE, Mihai C, Almarsson Ö, Sahay G. Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA. Nano Letters. PMID 28836442 DOI: 10.1021/Acs.Nanolett.7B02664  0.416
2017 Patel S, Sahay G. Abstract B56: Breaching endosomal barriers for carried-mediated intracellular delivery of messenger RNA Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B56  0.316
2016 Stewart MP, Sharei A, Ding X, Sahay G, Langer R, Jensen KF. In vitro and ex vivo strategies for intracellular delivery. Nature. 538: 183-192. PMID 27734871 DOI: 10.1038/Nature19764  0.558
2016 Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Scientific Reports. 6: 31750. PMID 27572704 DOI: 10.1038/Srep31750  0.34
2016 Stewart MP, Lorenz A, Dahlman J, Sahay G. Challenges in carrier-mediated intracellular delivery: moving beyond endosomal barriers. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 8: 465-78. PMID 26542891 DOI: 10.1002/Wnan.1377  0.386
2015 Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang BC, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, et al. Neutrophil Responses to Sterile Implant Materials. Plos One. 10: e0137550. PMID 26355958 DOI: 10.1371/Journal.Pone.0137550  0.708
2014 Xue W, Dahlman JE, Tammela T, Khan OF, Sood S, Dave A, Cai W, Chirino LM, Yang GR, Bronson R, Crowley DG, Sahay G, Schroeder A, Langer R, Anderson DG, et al. Small RNA combination therapy for lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 111: E3553-61. PMID 25114235 DOI: 10.1073/Pnas.1412686111  0.632
2014 Eltoukhy AA, Sahay G, Cunningham JM, Anderson DG. Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles. Acs Nano. 8: 7905-13. PMID 25010491 DOI: 10.1021/Nn501630H  0.651
2014 Dahlman JE, Barnes C, Khan OF, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, et al. In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nature Nanotechnology. 9: 648-55. PMID 24813696 DOI: 10.1038/Nnano.2014.84  0.754
2014 Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, et al. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. Proceedings of the National Academy of Sciences of the United States of America. 111: 3955-60. PMID 24516150 DOI: 10.1073/Pnas.1322937111  0.755
2013 Karagiannis ED, Urbanska AM, Sahay G, Pelet JM, Jhunjhunwala S, Langer R, Anderson DG. Rational design of a biomimetic cell penetrating peptide library. Acs Nano. 7: 8616-26. PMID 24047542 DOI: 10.1021/Nn4027382  0.647
2013 Alabi CA, Love KT, Sahay G, Yin H, Luly KM, Langer R, Anderson DG. Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery. Proceedings of the National Academy of Sciences of the United States of America. 110: 12881-6. PMID 23882076 DOI: 10.1073/Pnas.1306529110  0.782
2013 Sahay G, Querbes W, Alabi C, Eltoukhy A, Sarkar S, Zurenko C, Karagiannis E, Love K, Chen D, Zoncu R, Buganim Y, Schroeder A, Langer R, Anderson DG. Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling. Nature Biotechnology. 31: 653-8. PMID 23792629 DOI: 10.1038/Nbt.2614  0.794
2013 Heller DA, Levi Y, Pelet JM, Doloff JC, Wallas J, Pratt GW, Jiang S, Sahay G, Schroeder A, Schroeder JE, Chyan Y, Zurenko C, Querbes W, Manzano M, Kohane DS, et al. Modular 'click-in-emulsion' bone-targeted nanogels. Advanced Materials (Deerfield Beach, Fla.). 25: 1449-54. PMID 23280931 DOI: 10.1002/Adma.201202881  0.731
2013 Ma M, Chiu A, Sahay G, Doloff JC, Dholakia N, Thakrar R, Cohen J, Vegas A, Chen D, Bratlie KM, Dang T, York RL, Hollister-Lock J, Weir GC, Anderson DG. Core-shell hydrogel microcapsules for improved islets encapsulation. Advanced Healthcare Materials. 2: 667-72. PMID 23208618 DOI: 10.1002/Adhm.201200341  0.732
2013 Alabi CA, Sahay G, Langer R, Anderson DG. Development of siRNA-probes for studying intracellular trafficking of siRNA nanoparticles. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 224-30. PMID 23014672 DOI: 10.1039/C2Ib20155K  0.768
2013 Ma M, Chiu A, Sahay G, Doloff JC, Dholakia N, Thakrar R, Cohen J, Vegas A, Chen D, Bratlie KM, Dang T, York RL, Hollister-Lock J, Weir GC, Anderson DG. Cell Delivery: Core-Shell Hydrogel Microcapsules for Improved Islets Encapsulation (Adv. Healthcare Mater. 5/2013) Advanced Healthcare Materials. 2: 768-768. DOI: 10.1002/Adhm.201370026  0.76
2012 Alabi CA, Love KT, Sahay G, Stutzman T, Young WT, Langer R, Anderson DG. FRET-labeled siRNA probes for tracking assembly and disassembly of siRNA nanocomplexes. Acs Nano. 6: 6133-41. PMID 22693946 DOI: 10.1021/Nn3013838  0.765
2012 Chen D, Love KT, Chen Y, Eltoukhy AA, Kastrup C, Sahay G, Jeon A, Dong Y, Whitehead KA, Anderson DG. Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. Journal of the American Chemical Society. 134: 6948-51. PMID 22475086 DOI: 10.1021/Ja301621Z  0.716
2012 Schroeder A, Dahlman JE, Sahay G, Love KT, Jiang S, Eltoukhy AA, Levins CG, Wang Y, Anderson DG. Alkane-modified short polyethyleneimine for siRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 172-6. PMID 22155553 DOI: 10.1016/J.Jconrel.2011.11.030  0.632
2011 Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America. 108: 12996-3001. PMID 21784981 DOI: 10.1073/Pnas.1106379108  0.788
2011 Whitehead KA, Sahay G, Li GZ, Love KT, Alabi CA, Ma M, Zurenko C, Querbes W, Langer RS, Anderson DG. Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1688-94. PMID 21750531 DOI: 10.1038/Mt.2011.141  0.784
2011 Luxenhofer R, Sahay G, Schulz A, Alakhova D, Bronich TK, Jordan R, Kabanov AV. Structure-property relationship in cytotoxicity and cell uptake of poly(2-oxazoline) amphiphiles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 73-82. PMID 21513750 DOI: 10.1016/J.Jconrel.2011.04.010  0.757
2010 Kim JO, Sahay G, Kabanov AV, Bronich TK. Polymeric micelles with ionic cores containing biodegradable cross-links for delivery of chemotherapeutic agents. Biomacromolecules. 11: 919-26. PMID 20307096 DOI: 10.1021/Bm9013364  0.554
2010 Sahay G, Alakhova DY, Kabanov AV. Endocytosis of nanomedicines. Journal of Controlled Release : Official Journal of the Controlled Release Society. 145: 182-95. PMID 20226220 DOI: 10.1016/J.Jconrel.2010.01.036  0.778
2010 Sahay G, Gautam V, Luxenhofer R, Kabanov AV. The utilization of pathogen-like cellular trafficking by single chain block copolymer. Biomaterials. 31: 1757-64. PMID 19963266 DOI: 10.1016/J.Biomaterials.2009.11.020  0.545
2010 Sahay G, Kim JO, Kabanov AV, Bronich TK. The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents. Biomaterials. 31: 923-33. PMID 19853293 DOI: 10.1016/J.Biomaterials.2009.09.101  0.549
2008 Yang Z, Sahay G, Sriadibhatla S, Kabanov AV. Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA. Bioconjugate Chemistry. 19: 1987-94. PMID 18729495 DOI: 10.1021/Bc800144A  0.743
2008 Sahay G, Batrakova EV, Kabanov AV. Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport. Bioconjugate Chemistry. 19: 2023-9. PMID 18729494 DOI: 10.1021/Bc8002315  0.547
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