| Year |
Citation |
Score |
| 2021 |
Hebbel RP, Vercellotti GM. Multiple Inducers of endothelial NOS (eNOS) Dysfunction in Sickle Cell Disease. American Journal of Hematology. PMID 34331722 DOI: 10.1002/ajh.26308 |
0.303 |
|
| 2020 |
Hebbel RP, Wei P, Milbauer L, Corban MT, Solovey A, Kiley J, Pattee J, Lerman LO, Pan W, Lerman A. Abnormal Endothelial Gene Expression Associated With Early Coronary Atherosclerosis. Journal of the American Heart Association. e016134. PMID 32673514 DOI: 10.1161/Jaha.120.016134 |
0.33 |
|
| 2020 |
Patel MR, Jacobson BA, Ji Y, Hebbel RP, Kratzke RA. Blood Outgrowth Endothelial Cells as a Cellular Carrier for Oncolytic Vesicular Stomatitis Virus Expressing Interferon-β in Preclinical Models of Non-Small Cell Lung Cancer. Translational Oncology. 13: 100782. PMID 32422574 DOI: 10.1016/J.Tranon.2020.100782 |
0.329 |
|
| 2020 |
Hebbel RP, Belcher JD, Vercellotti GM. The multifaceted role of ischemia/reperfusion in sickle cell anemia. The Journal of Clinical Investigation. 130: 1062-1072. PMID 32118586 DOI: 10.1172/Jci133639 |
0.316 |
|
| 2019 |
Somani A, Nair SL, Milbauer LC, Zhu G, Sajja S, Solovey A, Chen Y, Hebbel RP. Blood outgrowth endothelial cells overexpressing eNOS mitigate pulmonary hypertension in rats: a unique carrier cell enabling autologous cell-based gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 31082372 DOI: 10.1016/J.Trsl.2019.04.005 |
0.374 |
|
| 2019 |
Gupta K, Chen C, Lutty GA, Hebbel RP. Morphine promotes neovascularizing retinopathy in sickle transgeneic mice. Blood Advances. 3: 1073-1083. PMID 30944099 DOI: 10.1182/Bloodadvances.2018026898 |
0.368 |
|
| 2017 |
Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP. A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade. American Journal of Hematology. PMID 28699284 DOI: 10.1002/Ajh.24856 |
0.434 |
|
| 2017 |
Hebbel RP. Blood endothelial cells: utility from ambiguity Journal of Clinical Investigation. 127: 1613-1615. PMID 28459428 DOI: 10.1172/Jci93649 |
0.419 |
|
| 2017 |
Mulrooney DA, Ness KK, Huang S, Santucci A, Hebbel RP, Solovey AS, Duprez D, Ehrhardt MJ, Green DM, Srivastava D, Robison LL, Hudson MM. Endothelial dysfunction in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort study. Journal of Clinical Oncology. 35: 10564-10564. DOI: 10.1200/Jco.2017.35.15_Suppl.10564 |
0.316 |
|
| 2016 |
Hebbel RP, Key NS. Microparticles in sickle cell anaemia: promise and pitfalls. British Journal of Haematology. PMID 27136195 DOI: 10.1111/Bjh.14112 |
0.393 |
|
| 2016 |
Ryder JR, O'Connell MJ, Rudser KD, Fox CK, Solovey AN, Hebbel RP, Kelly AS. Reproducibility of circulating endothelial cell enumeration and activation in children and adolescents. Biomarkers in Medicine. PMID 27071934 DOI: 10.2217/Bmm-2015-0051 |
0.36 |
|
| 2014 |
Vercellotti GM, Khan FB, Nguyen J, Chen C, Bruzzone CM, Bechtel H, Brown G, Nath KA, Steer CJ, Hebbel RP, Belcher JD. H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice. Frontiers in Pharmacology. 5: 79. PMID 24860503 DOI: 10.3389/Fphar.2014.00079 |
0.386 |
|
| 2014 |
Hebbel RP. Ischemia-reperfusion injury in sickle cell anemia: relationship to acute chest syndrome, endothelial dysfunction, arterial vasculopathy, and inflammatory pain. Hematology/Oncology Clinics of North America. 28: 181-98. PMID 24589261 DOI: 10.1016/J.Hoc.2013.11.005 |
0.364 |
|
| 2014 |
Sparkenbaugh EM, Chantrathammachart P, Mickelson J, van Ryn J, Hebbel RP, Monroe DM, Mackman N, Key NS, Pawlinski R. Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease. Blood. 123: 1747-56. PMID 24449213 DOI: 10.1182/Blood-2013-08-523936 |
0.448 |
|
| 2014 |
Meier LA, Syedain ZH, Lahti MT, Johnson SS, Chen MH, Hebbel RP, Tranquillo RT. Blood outgrowth endothelial cells alter remodeling of completely biological engineered grafts implanted into the sheep femoral artery. Journal of Cardiovascular Translational Research. 7: 242-9. PMID 24429838 DOI: 10.1007/S12265-013-9539-Z |
0.366 |
|
| 2014 |
Belcher JD, Chen C, Nguyen J, Milbauer L, Abdulla F, Alayash AI, Smith A, Nath KA, Hebbel RP, Vercellotti GM. Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease. Blood. 123: 377-90. PMID 24277079 DOI: 10.1182/Blood-2013-04-495887 |
0.374 |
|
| 2013 |
Weber ML, Chen C, Li Y, Farooqui M, Nguyen J, Poonawala T, Hebbel RP, Gupta K. Morphine stimulates platelet-derived growth factor receptor-β signalling in mesangial cells in vitro and transgenic sickle mouse kidney in vivo. British Journal of Anaesthesia. 111: 1004-12. PMID 23820675 DOI: 10.1093/Bja/Aet221 |
0.352 |
|
| 2013 |
Swarnalatha B, Nair SL, Shalumon KT, Milbauer LC, Jayakumar R, Paul-Prasanth B, Menon KK, Hebbel RP, Somani A, Nair SV. Poly (lactic acid)-chitosan-collagen composite nanofibers as substrates for blood outgrowth endothelial cells. International Journal of Biological Macromolecules. 58: 220-4. PMID 23548861 DOI: 10.1016/J.Ijbiomac.2013.03.060 |
0.393 |
|
| 2013 |
Shirodkar AV, St Bernard R, Gavryushova A, Kop A, Knight BJ, Yan MS, Man HS, Sud M, Hebbel RP, Oettgen P, Aird WC, Marsden PA. A mechanistic role for DNA methylation in endothelial cell (EC)-enriched gene expression: relationship with DNA replication timing. Blood. 121: 3531-40. PMID 23449636 DOI: 10.1182/Blood-2013-01-479170 |
0.328 |
|
| 2013 |
Nath KA, Grande JP, Farrugia G, Croatt AJ, Belcher JD, Hebbel RP, Vercellotti GM, Katusic ZS. Age sensitizes the kidney to heme protein-induced acute kidney injury. American Journal of Physiology. Renal Physiology. 304: F317-25. PMID 23195679 DOI: 10.1152/Ajprenal.00606.2012 |
0.313 |
|
| 2013 |
Solovey A, Somani A, Chen C, Kiley J, Marker P, Abdulla F, O'Sullivan MG, Kelm RJ, Belcher JD, Vercellotti GM, Hebbel RP. Interference With TNFα Using Long-Term Etanercept In S+SAntilles Sickle Transgenic Mice Ameliorates Abnormal Endothelial Activation, Vasoocclusion, and Pulmonary Hypertension Including Its Pulmonary Arterial Wall Remodeling Blood. 122: 728-728. DOI: 10.1182/Blood.V122.21.728.728 |
0.436 |
|
| 2012 |
Martin-Ramirez J, Hofman M, van den Biggelaar M, Hebbel RP, Voorberg J. Establishment of outgrowth endothelial cells from peripheral blood. Nature Protocols. 7: 1709-15. PMID 22918388 DOI: 10.1038/Nprot.2012.093 |
0.44 |
|
| 2012 |
Mulrooney DA, Ness KK, Solovey A, Hebbel RP, Neaton JD, Peterson BA, Lee CK, Kelly AS, Neglia JP. Pilot study of vascular health in survivors of Hodgkin lymphoma. Pediatric Blood & Cancer. 59: 285-9. PMID 22457206 DOI: 10.1002/Pbc.24082 |
0.302 |
|
| 2012 |
Manning BM, Hebbel RP, Gupta K, Haynes CL. Carbon-fiber microelectrode amperometry reveals sickle-cell-induced inflammation and chronic morphine effects on single mast cells. Acs Chemical Biology. 7: 543-51. PMID 22217155 DOI: 10.1021/Cb200347Q |
0.397 |
|
| 2012 |
Vercellotti GM, Chen C, Bruzzone CM, Bechtel HA, Ngyuen J, Hebbel RP, Steer CJ, Belcher JD. H-Ferritin Ferroxidase Activity Induces Cytoprotective Pathways and Inhibits Microvascular Stasis in Transgenic Sickle Mice Blood. 120: 378-378. DOI: 10.1182/Blood.V120.21.378.378 |
0.386 |
|
| 2012 |
Vincent L, Nguyen J, Vang D, Taiwo OB, Luk K, Ansonoff M, Ericson M, Simone D, Pintar JE, Hebbel RP, Gupta K. Mast Cell Activation Contributes to Neurogenic Inflammation and Pain in Sickle Cell Disease Blood. 120: 374-374. DOI: 10.1182/Blood.V120.21.374.374 |
0.397 |
|
| 2011 |
Sjeklocha LM, Park CW, Wong PY, Roney MJ, Belcher JD, Kaufman DS, Vercellotti GM, Hebbel RP, Steer CJ. Erythroid-specific expression of β-globin from Sleeping Beauty-transduced human hematopoietic progenitor cells. Plos One. 6: e29110. PMID 22216176 DOI: 10.1371/Journal.Pone.0029110 |
0.307 |
|
| 2011 |
Kang L, Yamada S, Hernandez MC, Croatt AJ, Grande JP, Juncos JP, Vercellotti GM, Hebbel RP, Katusic ZS, Terzic A, Nath KA. Regional and systemic hemodynamic responses following the creation of a murine arteriovenous fistula. American Journal of Physiology. Renal Physiology. 301: F845-51. PMID 21697243 DOI: 10.1152/Ajprenal.00311.2011 |
0.347 |
|
| 2011 |
Ahmann KA, Johnson SL, Hebbel RP, Tranquillo RT. Shear stress responses of adult blood outgrowth endothelial cells seeded on bioartificial tissue. Tissue Engineering. Part A. 17: 2511-21. PMID 21599543 DOI: 10.1089/Ten.Tea.2011.0055 |
0.39 |
|
| 2011 |
Gavins FN, Russell J, Senchenkova EL, De Almeida Paula L, Damazo AS, Esmon CT, Kirchhofer D, Hebbel RP, Granger DN. Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S. Blood. 117: 4125-33. PMID 21304105 DOI: 10.1182/Blood-2010-08-301366 |
0.344 |
|
| 2011 |
Hebbel RP. Reconstructing sickle cell disease: a data-based analysis of the "hyperhemolysis paradigm" for pulmonary hypertension from the perspective of evidence-based medicine. American Journal of Hematology. 86: 123-54. PMID 21264896 DOI: 10.1002/Ajh.21952 |
0.323 |
|
| 2011 |
Wei P, Milbauer L, Enenstein J, Nguyen J, Pan W, Hebbel RP. Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer. Bmc Medicine. 9: 2-2. PMID 21223544 DOI: 10.1186/1741-7015-9-2 |
0.317 |
|
| 2011 |
Juncos R, Juncos L, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA. Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease. Journal of Cardiovascular Pharmacology. 57: 263-6. PMID 21107280 DOI: 10.1097/Fjc.0B013E318204Bb34 |
0.334 |
|
| 2011 |
Belcher JD, Nguyen J, Chen C, Smith A, Alayash AI, Nair SL, Somani A, Hebbel RP, Vercellotti GM. Plasma Hemoglobin and Heme Trigger Weibel Palade Body Exocytosis and Vaso-Occlusion in Transgenic Sickle Mice Blood. 118: 896-896. DOI: 10.1182/Blood.V118.21.896.896 |
0.434 |
|
| 2011 |
Luk K, Nguyen J, Vang D, Taiwo OB, Kohli D, Ericson M, Ansonoff MA, Pintar JE, Hebbel RP, Gupta K. Association of Mu Opioid Receptor with Neurogenic Inflammation in Sickle Mic Blood. 118: 895-895. DOI: 10.1182/Blood.V118.21.895.895 |
0.386 |
|
| 2011 |
Vang D, Ericson M, Ansonoff MA, Pintar JE, Hebbel RP, Gupta K. Morphine Stimulates Wound Healing Via Mu Opioid Receptor and Promotes Wound Closure in Sickle Mice Blood. 118: 2118-2118. DOI: 10.1182/Blood.V118.21.2118.2118 |
0.321 |
|
| 2011 |
Beckman JD, Marker PH, Nguyen J, Belcher JD, Croatt AJ, Nath KA, Hebbel RP, Vercellotti GM. Carbon Monoxide Therapy Modulates Hematopoietic Stem Cell Development in Heme-Oxygenase-1 Knockout Mice Blood. 118: 1318-1318. DOI: 10.1182/Blood.V118.21.1318.1318 |
0.377 |
|
| 2011 |
Solovey A, Chang LM, Abdulla F, Kollander R, Marker PH, Kelm R, Vercellotti GM, Hebbel RP. The Blood Monocyte - TNF - Endothelial Axis in Activation of Endothelial Tissue Factor in the Transgenic Sickle Mouse: Possible Relevance of Etanercept to Sickle Coagulopathy Blood. 118: 1048-1048. DOI: 10.1182/Blood.V118.21.1048.1048 |
0.38 |
|
| 2010 |
Bodempudi V, Ohlfest JR, Terai K, Zamora EA, Vogel RI, Gupta K, Hebbel RP, Dudek AZ. Blood outgrowth endothelial cell-based systemic delivery of antiangiogenic gene therapy for solid tumors. Cancer Gene Therapy. 17: 855-63. PMID 20725100 DOI: 10.1038/Cgt.2010.42 |
0.411 |
|
| 2010 |
Somani A, Steiner ME, Hebbel RP. The dynamic regulation of microcirculatory conduit function: features relevant to transfusion medicine. Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society For Haemapheresis. 43: 61-8. PMID 20580315 DOI: 10.1016/J.Transci.2010.05.010 |
0.358 |
|
| 2010 |
Bunn HF, Nathan DG, Dover GJ, Hebbel RP, Platt OS, Rosse WF, Ware RE. Pulmonary hypertension and nitric oxide depletion in sickle cell disease. Blood. 116: 687-92. PMID 20395414 DOI: 10.1182/Blood-2010-02-268193 |
0.313 |
|
| 2010 |
Kohli DR, Li Y, Khasabov SG, Gupta P, Kehl LJ, Ericson ME, Nguyen J, Gupta V, Hebbel RP, Simone DA, Gupta K. Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids. Blood. 116: 456-65. PMID 20304807 DOI: 10.1182/Blood-2010-01-260372 |
0.34 |
|
| 2010 |
Kollander R, Solovey A, Milbauer LC, Abdulla F, Kelm RJ, Hebbel RP. Nuclear factor-kappa B (NFkappaB) component p50 in blood mononuclear cells regulates endothelial tissue factor expression in sickle transgenic mice: implications for the coagulopathy of sickle cell disease. Translational Research : the Journal of Laboratory and Clinical Medicine. 155: 170-7. PMID 20303465 DOI: 10.1016/J.Trsl.2009.10.004 |
0.473 |
|
| 2010 |
Juncos JP, Grande JP, Croatt AJ, Hebbel RP, Vercellotti GM, Katusic ZS, Nath KA. Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease. American Journal of Physiology. Renal Physiology. 298: F892-9. PMID 20107113 DOI: 10.1152/Ajprenal.00631.2009 |
0.345 |
|
| 2010 |
Hebbel RP, Vercellotti GM, Pace BS, Solovey AN, Kollander R, Abanonu CF, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm RJ, Slungaard A. The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice. Blood. 115: 2483-90. PMID 20053759 DOI: 10.1182/Blood-2009-02-204990 |
0.454 |
|
| 2010 |
Solovey A, Kollander R, Milbauer LC, Abdulla F, Chen Y, Kelm RJ, Hebbel RP. Endothelial nitric oxide synthase and nitric oxide regulate endothelial tissue factor expression in vivo in the sickle transgenic mouse. American Journal of Hematology. 85: 41-5. PMID 20029945 DOI: 10.1002/Ajh.21582 |
0.414 |
|
| 2010 |
Enenstein J, Milbauer L, Domingo E, Wells A, Roney M, Kiley J, Wei P, Hebbel RP. Proinflammatory phenotype with imbalance of KLF2 and RelA: risk of childhood stroke with sickle cell anemia. American Journal of Hematology. 85: 18-23. PMID 19957349 DOI: 10.1002/Ajh.21558 |
0.309 |
|
| 2010 |
Beckman JD, Marker PH, Nguyen J, Belcher JD, Hebbel RP, Croatt AJ, Nath KA, Vercellotti GM. Carbon Monoxide Therapy Reduces Reactive Oxygen Species Production and the Short-Term Hematopoietic Stem Cell Population In Heme-Oxygenase-1 Knockout Mice Blood. 116: 4767-4767. DOI: 10.1182/Blood.V116.21.4767.4767 |
0.367 |
|
| 2010 |
Belcher JD, Nguyen J, Furne J, Vineyard J, Beckman JD, Marker PH, Hebbel RP, Levitt MD, Vercellotti GM. Exhaled Carbon Monoxide as a Marker of Hemolysis In Transgenic Mouse Models of Sickle Cell Anemia. Blood. 116: 1642-1642. DOI: 10.1182/Blood.V116.21.1642.1642 |
0.401 |
|
| 2009 |
John R, Panch S, Hrabe J, Wei P, Solovey A, Joyce L, Hebbel R. Activation of Endothelial and Coagulation Systems in Left Ventricular Assist Device Recipients The Annals of Thoracic Surgery. 88: 1171-1179. PMID 19766802 DOI: 10.1016/J.Athoracsur.2009.06.095 |
0.361 |
|
| 2009 |
Hebbel RP, Vercellotti G, Nath KA. A systems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxsis. Cardiovascular & Hematological Disorders Drug Targets. 9: 271-92. PMID 19751187 DOI: 10.2174/1871529X10909040271 |
0.346 |
|
| 2009 |
Hasstedt SJ, Bezemer ID, Callas PW, Vossen CY, Trotman W, Hebbel RP, Demers C, Rosendaal FR, Bovill EG. Cell adhesion molecule 1: a novel risk factor for venous thrombosis. Blood. 114: 3084-91. PMID 19643986 DOI: 10.1182/Blood-2009-05-219485 |
0.336 |
|
| 2009 |
Beckman JD, Belcher JD, Vineyard JV, Chen C, Nguyen J, Nwaneri MO, O'Sullivan MG, Gulbahce E, Hebbel RP, Vercellotti GM. Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1243-53. PMID 19617415 DOI: 10.1152/Ajpheart.00327.2009 |
0.418 |
|
| 2009 |
Kato GJ, Hebbel RP, Steinberg MH, Gladwin MT. Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions. American Journal of Hematology. 84: 618-25. PMID 19610078 DOI: 10.1002/Ajh.21475 |
0.418 |
|
| 2009 |
Wang H, Zhang W, Tang R, Hebbel RP, Kowalska MA, Zhang C, Marth JD, Fukuda M, Zhu C, Huo Y. Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1053-9. PMID 19372458 DOI: 10.1161/Atvbaha.109.187716 |
0.313 |
|
| 2009 |
van den Biggelaar M, Bouwens EA, Kootstra NA, Hebbel RP, Voorberg J, Mertens K. Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells. Haematologica. 94: 670-8. PMID 19336741 DOI: 10.3324/Haematol.13427 |
0.378 |
|
| 2009 |
Milbauer LC, Enenstein JA, Roney M, Solovey A, Bodempudi V, Nichols TC, Hebbel RP. Blood outgrowth endothelial cell migration and trapping in vivo: a window into gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 153: 179-89. PMID 19304277 DOI: 10.1016/J.Trsl.2008.12.009 |
0.409 |
|
| 2009 |
Gupta K, Schwartz R, Gupta P, Hebbel RP. Thrombospondin Inhibits VEGF-Induced Endothelial Survival and Cell Cycle Progression The Open Circulation & Vascular Journal. 2: 1-9. DOI: 10.2174/1877382600902010001 |
0.367 |
|
| 2009 |
Kohli DR, Li Y, Khasabov SG, Ericson ME, Gupta P, Simone DA, Hebbel RP, Gupta K. Cannabinoids as Analgesics for Pain in Sickle Cell Disease. Blood. 114: 822-822. DOI: 10.1182/Blood.V114.22.822.822 |
0.328 |
|
| 2009 |
Hebbel RP, Vercellotti GM, Pace B, Solovey A, Kollander R, Abanonu C, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm R, Slungaard A. The HDAC Inhibitors Trichostatin A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA) Exhibit Multiple Modalities of Benefit for the Vascular Pathology of Sickle Disease. Blood. 114: 2586-2586. DOI: 10.1182/Blood.V114.22.2586.2586 |
0.389 |
|
| 2008 |
Chang Milbauer L, Wei P, Enenstein J, Jiang A, Hillery CA, Scott JP, Nelson SC, Bodempudi V, Topper JN, Yang RB, Hirsch B, Pan W, Hebbel RP. Genetic endothelial systems biology of sickle stroke risk. Blood. 111: 3872-9. PMID 18156497 DOI: 10.1182/Blood-2007-06-097188 |
0.38 |
|
| 2008 |
Bovill E, Bezemer ID, Hasstedt SJ, Callas PW, Hebbel RP, Rosendaal F. IGSF4: A Novel Candidate Gene for Venous Thrombosis Blood. 112: 405-405. DOI: 10.1182/Blood.V112.11.405.405 |
0.33 |
|
| 2008 |
Musibay ED, Milbauer L, Enenstein J, Wells A, Hebbel RP. Association of Inflammatory Transcription Factors in Human Blood Outgrowth Endothelial Cells and Development of Stroke in Sickle Cell Disease The Faseb Journal. 22: 43-43. DOI: 10.1096/Fasebj.22.2_Supplement.43 |
0.379 |
|
| 2008 |
Panch SR, Hrabe J, Solovey A, Toninato C, Hebbel RP, John R. 96: Sustained Activation of Vascular Endothelium Induces the Tissue Factor Pathway in LVAD Recipients Journal of Heart and Lung Transplantation. 27. DOI: 10.1016/J.Healun.2007.11.101 |
0.321 |
|
| 2007 |
Jiang A, Pan W, Milbauer LC, Shyr Y, Hebbel RP. A practical question based on cross-platform microarray data normalization: are BOEC more like large vessel or microvascular endothelial cells or neither of them? Journal of Bioinformatics and Computational Biology. 5: 875-93. PMID 17787061 DOI: 10.1142/S0219720007002989 |
0.38 |
|
| 2007 |
Dudek AZ, Bodempudi V, Welsh BW, Jasinski P, Griffin RJ, Milbauer L, Hebbel RP. Systemic inhibition of tumour angiogenesis by endothelial cell-based gene therapy. British Journal of Cancer. 97: 513-522. PMID 17653078 DOI: 10.1038/Sj.Bjc.6603883 |
0.44 |
|
| 2007 |
Matsui H, Shibata M, Brown B, Labelle A, Hegadorn C, Andrews C, Hebbel RP, Galipeau J, Hough C, Lillicrap D. Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors. Stem Cells (Dayton, Ohio). 25: 2660-9. PMID 17615271 DOI: 10.1634/Stemcells.2006-0699 |
0.366 |
|
| 2007 |
Somani A, Nguyen J, Milbauer LC, Solovey A, Sajja S, Hebbel RP. The establishment of murine blood outgrowth endothelial cells and observations relevant to gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 150: 30-9. PMID 17585861 DOI: 10.1016/J.Trsl.2007.02.002 |
0.441 |
|
| 2007 |
Kren BT, Yin W, Key NS, Hebbel RP, Steer CJ. Blood outgrowth endothelial cells as a vehicle for transgene expression of hepatocyte-secreted proteins via Sleeping Beauty. Endothelium : Journal of Endothelial Cell Research. 14: 97-104. PMID 17497366 DOI: 10.1080/10623320701346932 |
0.39 |
|
| 2007 |
Lunzer MM, Yekkirala A, Hebbel RP, Portoghese PS. Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia. Proceedings of the National Academy of Sciences of the United States of America. 104: 6061-5. PMID 17389363 DOI: 10.1073/Pnas.0700295104 |
0.329 |
|
| 2007 |
Gupta K, Chen C, Ericson ME, Hebbel RP, Li Y. Characterization of Pain, Vasculature and Innervation in Sickle Cell Disease. Blood. 110: 2248-2248. DOI: 10.1182/Blood.V110.11.2248.2248 |
0.314 |
|
| 2007 |
Wu Y, Schmuckler N, Hebbel R, Colman R. Cleaved Kininogen Inhibits Capillary Tube Formation by Circulating Endothelial Cells via inhibiting matrix metalloprotease-2 (MMP-2) The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A194-C |
0.307 |
|
| 2006 |
Dasgupta T, Hebbel RP, Kaul DK. Protective effect of arginine on oxidative stress in transgenic sickle mouse models. Free Radical Biology & Medicine. 41: 1771-80. PMID 17157180 DOI: 10.1016/J.Freeradbiomed.2006.08.025 |
0.344 |
|
| 2006 |
Pan W, Shen X, Jiang A, Hebbel RP. Semi-supervised learning via penalized mixture model with application to microarray sample classification. Bioinformatics (Oxford, England). 22: 2388-95. PMID 16870935 DOI: 10.1093/Bioinformatics/Btl393 |
0.335 |
|
| 2006 |
Kaul DK, Kollander R, Mahaseth H, Liu XD, Solovey A, Belcher J, Kelm RJ, Vercellotti GM, Hebbel RP. Robust vascular protective effect of hydroxamic acid derivatives in a sickle mouse model of inflammation. Microcirculation (New York, N.Y. : 1994). 13: 489-97. PMID 16864415 DOI: 10.1080/10739680600778456 |
0.393 |
|
| 2006 |
Juncos JP, Grande JP, Murali N, Croatt AJ, Juncos LA, Hebbel RP, Katusic ZS, Nath KA. Anomalous renal effects of tin protoporphyrin in a murine model of sickle cell disease. The American Journal of Pathology. 169: 21-31. PMID 16816358 DOI: 10.2353/Ajpath.2006.051195 |
0.348 |
|
| 2006 |
Wood KC, Hebbel RP, Lefer DJ, Granger DN. Critical role of endothelial cell-derived nitric oxide synthase in sickle cell disease-induced microvascular dysfunction. Free Radical Biology & Medicine. 40: 1443-53. PMID 16631534 DOI: 10.1016/J.Freeradbiomed.2005.12.015 |
0.429 |
|
| 2006 |
Belcher JD, Mahaseth H, Welch TE, Otterbein LE, Hebbel RP, Vercellotti GM. Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. The Journal of Clinical Investigation. 116: 808-16. PMID 16485041 DOI: 10.1172/Jci26857 |
0.384 |
|
| 2006 |
De Meyer SF, Vanhoorelbeke K, Chuah MK, Pareyn I, Gillijns V, Hebbel RP, Collen D, Deckmyn H, VandenDriessche T. Phenotypic correction of von Willebrand disease type 3 blood-derived endothelial cells with lentiviral vectors expressing von Willebrand factor. Blood. 107: 4728-36. PMID 16478886 DOI: 10.1182/Blood-2005-09-3605 |
0.368 |
|
| 2006 |
Stachelek SJ, Alferiev I, Connolly JM, Sacks M, Hebbel RP, Bianco R, Levy RJ. Cholesterol-modified polyurethane valve cusps demonstrate blood outgrowth endothelial cell adhesion post-seeding in vitro and in vivo. The Annals of Thoracic Surgery. 81: 47-55. PMID 16368333 DOI: 10.1016/J.Athoracsur.2005.07.061 |
0.353 |
|
| 2006 |
Matsui H, Shibata M, Brown B, Labelle A, Hegadorn C, Andrews C, Hebbel RP, Galipeau J, Hough C, Lillicrap D. Ex Vivo Gene Trasfer for Hemophilia A That Enhances Safety and Results in Sustained In Vivo Factor VIII Expression from Lentivirally-Engineered Endothelial Progenitors. Blood. 108: 3251-3251. DOI: 10.1182/Blood.V108.11.3251.3251 |
0.382 |
|
| 2006 |
Gupta K, Li Y, Mason NA, Vang TS, Levay-Young BK, Erickson ME, Hebbel RP. Opioid Receptors Stimulate Angiogenesis, Lymphangiogenesis and Neurogenesis in Ischemic Wounds in Sickle Mice. Blood. 108: 1199-1199. DOI: 10.1182/Blood.V108.11.1199.1199 |
0.339 |
|
| 2006 |
Gupta K, Chen C, Lutty GA, Hebbel RP. Microenvironment-Induced Endothelial Heterogeneity Stimulates Retinal Neovascularization in Sickle Mice. Blood. 108: 1198-1198. DOI: 10.1182/Blood.V108.11.1198.1198 |
0.346 |
|
| 2005 |
Sieminski AL, Hebbel RP, Gooch KJ. Improved microvascular network in vitro by human blood outgrowth endothelial cells relative to vessel-derived endothelial cells Tissue Engineering. 11: 1332-1345. PMID 16259589 DOI: 10.1089/Ten.2005.11.1332 |
0.426 |
|
| 2005 |
Fernandez-L A, Sanz-Rodriguez F, Zarrabeitia R, Pérez-Molino A, Hebbel RP, Nguyen J, Bernabéu C, Botella LM. Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions. Cardiovascular Research. 68: 235-48. PMID 15993872 DOI: 10.1016/J.Cardiores.2005.06.009 |
0.378 |
|
| 2005 |
Mahaseth H, Vercellotti GM, Welch TE, Bowlin PR, Sonbol KM, Hsia CJ, Li M, Bischof JC, Hebbel RP, Belcher JD. Polynitroxyl albumin inhibits inflammation and vasoocclusion in transgenic sickle mice. The Journal of Laboratory and Clinical Medicine. 145: 204-11. PMID 15962839 DOI: 10.1016/J.Lab.2005.02.008 |
0.402 |
|
| 2005 |
Wood KC, Hebbel RP, Granger DN. Endothelial cell NADPH oxidase mediates the cerebral microvascular dysfunction in sickle cell transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 989-91. PMID 15923406 DOI: 10.1096/Fj.04-3218Fje |
0.439 |
|
| 2005 |
Nath KA, Grande JP, Croatt AJ, Frank E, Caplice NM, Hebbel RP, Katusic ZS. Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury. The American Journal of Pathology. 166: 963-72. PMID 15793278 DOI: 10.1016/S0002-9440(10)62318-8 |
0.324 |
|
| 2005 |
Blann AD, Woywodt A, Bertolini F, Bull TM, Buyon JP, Clancy RM, Haubitz M, Hebbel RP, Lip GY, Mancuso P, Sampol J, Solovey A, Dignat-George F. Circulating endothelial cells. Biomarker of vascular disease. Thrombosis and Haemostasis. 93: 228-35. PMID 15711737 DOI: 10.1160/Th04-09-0578 |
0.444 |
|
| 2005 |
Belcher JD, Mahaseth H, Welch TE, Vilback AE, Sonbol KM, Kalambur VS, Bowlin PR, Bischof JC, Hebbel RP, Vercellotti GM. Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2715-25. PMID 15665055 DOI: 10.1152/Ajpheart.00986.2004 |
0.449 |
|
| 2005 |
Stachelek SJ, Alferiev I, Choi H, Kronsteiner A, Uttayarat P, Gooch KJ, Composto RJ, Chen IW, Hebbel RP, Levy RJ. Cholesterol-derivatized polyurethane: characterization and endothelial cell adhesion. Journal of Biomedical Materials Research. Part A. 72: 200-12. PMID 15625684 DOI: 10.1002/Jbm.A.30224 |
0.385 |
|
| 2005 |
Hebbel RP, Wei P, Jiang A, Hillery C, Scott JP, Nelson SC, Enenstein J, Milbauer L, Bodempudi V, Pan W, Hirsch B, Topper JN, Yang R. Genetic Influence on the Systems Biology of Sickle Stroke Risk Detected by Endothelial Gene Expression. Blood. 110: 427-427. DOI: 10.1182/Blood.V110.11.427.427 |
0.327 |
|
| 2005 |
Gupta K, Poonawala T, Levay-Young BK, Ericson ME, Ammbashankar NS, Hebbel RP. Abnormal Angiogenesis, Neurogenesis and Lymphangiogenesis in the Skin Underlies Delayed Wound Healing in the Sickle Mouse: Acceleration of Healing by Topical Opioids. Blood. 106: 3177-3177. DOI: 10.1182/Blood.V106.11.3177.3177 |
0.359 |
|
| 2005 |
Weber ML, Hebbel RP, Gupta K. Morphine Induces Kidney Injury in Transgenic Sickle Cell Mice. Blood. 106: 3167-3167. DOI: 10.1182/Blood.V106.11.3167.3167 |
0.315 |
|
| 2005 |
Belcher JD, Mahaseth H, Welch TE, Boakye-Agyeman F, Hebbel RP, Vercellotti GM. Oxidative Stress and Vaso-Occlusion in Sickle Cell Disease: Role of Activated Leukocytes and Redox Active Iron. Blood. 106: 3165-3165. DOI: 10.1182/Blood.V106.11.3165.3165 |
0.418 |
|
| 2005 |
Hebbel RP, Kollander R, Solovey A, Choong S, Kelm RJ. Therapeutic Inhibition of Endothelial Cell Tissue Factor Expression In Vivo by Nitric Oxide and Arginine in Sickle Transgenic Mice. Blood. 106: 210-210. DOI: 10.1182/Blood.V106.11.210.210 |
0.422 |
|
| 2005 |
Gupta K, Chen C, Lutty GA, Hebbel RP. Morphine Exaggerates Retinopathy in Transgenic Sickle Mice. Blood. 106: 209-209. DOI: 10.1182/Blood.V106.11.209.209 |
0.33 |
|
| 2005 |
Kaul DK, Liu X, Dasgupta T, Zhang X, Choong S, Hebbel RP. Arginine Therapy Decreases Oxidative Stress and Attenuates Leukocyte Recruitment in Transgenic and Knockout Sickle Mice Resulting in Improved Microvascular Flow and Reduced Vaso-Occlusion. Blood. 106: 207-207. DOI: 10.1182/Blood.V106.11.207.207 |
0.367 |
|
| 2005 |
Hebbel RP, Milbauer L, Roney M, Lillicrap D, Voorberg J, Nichols TC. Use of Engineered Autologous BOEC for Gene Therapy of Canine Hemophilia A. Blood. 106: 1281-1281. DOI: 10.1182/Blood.V106.11.1281.1281 |
0.364 |
|
| 2004 |
Jy W, Horstman LL, Jimenez JJ, Ahn YS, Biró É, Nieuwland R, Sturk A, Dignat-George F, Sabatier F, Camoin-Jau L, Sampol J, Hugel B, Zobairi F, Freyssinet JM, Nomura S, ... ... Hebbel RP, et al. Measuring circulating cell-derived microparticles Journal of Thrombosis and Haemostasis. 2: 1842-1851. PMID 15456497 DOI: 10.1111/J.1538-7836.2004.00936.X |
0.316 |
|
| 2004 |
Kalambur VS, Mahaseth H, Bischof JC, Kielbik MC, Welch TE, Vilbäck A, Swanlund DJ, Hebbel RP, Belcher JD, Vercellotti GM. Microvascular blood flow and stasis in transgenic sickle mice: utility of a dorsal skin fold chamber for intravital microscopy. American Journal of Hematology. 77: 117-25. PMID 15389823 DOI: 10.1002/Ajh.20143 |
0.379 |
|
| 2004 |
Xia YF, Ye BQ, Li YD, Wang JG, He XJ, Lin X, Yao X, Ma D, Slungaard A, Hebbel RP, Key NS, Geng JG. Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50. Journal of Immunology (Baltimore, Md. : 1950). 173: 4207-17. PMID 15356172 DOI: 10.4049/Jimmunol.173.6.4207 |
0.319 |
|
| 2004 |
Hebbel RP, Osarogiagbon R, Kaul D. The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy. Microcirculation (New York, N.Y. : 1994). 11: 129-51. PMID 15280088 DOI: 10.1080/10739680490278402 |
0.402 |
|
| 2004 |
Wood K, Russell J, Hebbel RP, Granger DN. Differential expression of E- and P-selectin in the microvasculature of sickle cell transgenic mice. Microcirculation (New York, N.Y. : 1994). 11: 377-85. PMID 15280076 DOI: 10.1080/10739680490437559 |
0.414 |
|
| 2004 |
Sieminski AL, Hebbel RP, Gooch KJ. The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro Experimental Cell Research. 297: 574-584. PMID 15212957 DOI: 10.1016/J.Yexcr.2004.03.035 |
0.359 |
|
| 2004 |
Solovey A, Kollander R, Shet A, Milbauer LC, Choong S, Panoskaltsis-Mortari A, Blazar BR, Kelm RJ, Hebbel RP. Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin. Blood. 104: 840-6. PMID 15073034 DOI: 10.1182/Blood-2003-10-3719 |
0.413 |
|
| 2004 |
Kaul DK, Liu XD, Choong S, Belcher JD, Vercellotti GM, Hebbel RP. Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice. American Journal of Physiology. Heart and Circulatory Physiology. 287: H293-301. PMID 15001449 DOI: 10.1152/Ajpheart.01150.2003 |
0.409 |
|
| 2004 |
Aras O, Shet A, Bach RR, Hysjulien JL, Slungaard A, Hebbel RP, Escolar G, Jilma B, Key NS. Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia. Blood. 103: 4545-53. PMID 14988149 DOI: 10.1182/Blood-2003-03-0713 |
0.344 |
|
| 2004 |
Wood KC, Hebbel RP, Granger DN. Endothelial cell P-selectin mediates a proinflammatory and prothrombogenic phenotype in cerebral venules of sickle cell transgenic mice. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1608-14. PMID 14704223 DOI: 10.1152/Ajpheart.01056.2003 |
0.392 |
|
| 2004 |
Somani A, Nguyen J, Milbauer LC, Solovey A, Enenstein J, Hebbel RP. Development of a Murine Blood Outgrowth Endothelial Cell Culture System Chest. 126: 887. DOI: 10.1378/Chest.126.4_Meetingabstracts.887S |
0.388 |
|
| 2004 |
Mahaseth H, Belcher JD, Welch TE, Sonbol KM, Bowlin PR, Hebbel RP, Ma L, Hsia CJ, Vercellotti GM. Polynitroxyl Albumin Prevents Vaso-Occlusion in Transgenic Sickle Mice. Blood. 104: 366-366. DOI: 10.1182/Blood.V104.11.366.366 |
0.445 |
|
| 2004 |
Belcher JD, Welch TE, Mahaseth H, Sonbol KM, Bowlin PR, Bischof JC, Hebbel RP, Vercellotti GM. Heme Oxygenase-1: A Potential Modulator of Inflammation and Vaso-Occlusion in Sickle Cell Disease. Blood. 104: 365-365. DOI: 10.1182/Blood.V104.11.365.365 |
0.431 |
|
| 2004 |
Dudek AZ, Bodempudi V, Nelson CM, Chang L, Hebbel RP. Blood Outgrowth Endothelial Cells (BOEC) Contribute to Tumor Vascularization and Can Be Used for Delivery of Cancer Gene Therapy. Blood. 104: 3173-3173. DOI: 10.1182/Blood.V104.11.3173.3173 |
0.398 |
|
| 2004 |
Hebbel RP. Special Issue of Microcirculation: Examination of the Vascular Pathobiology of Sickle Cell Anemia Microcirculation. 11: 99-100. DOI: 10.1080/10739680490278240 |
0.409 |
|
| 2004 |
Stachelek SJ, Alferiev IS, Zoltick PW, Connolly JM, Bianco RW, Hebbel RP, Levy RJ. 200. Cholesterol Modified Polyurethane as a Matrix for Cell Based Cardiovascular Therapy Using Blood Outgrowth Endothelial Cells (BOEC): Potential for Lentivirus Mediated Gene Therapy Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.108 |
0.389 |
|
| 2003 |
Hebbel RP. Sickle hemoglobin instability: a mechanism for malarial protection. Redox Report : Communications in Free Radical Research. 8: 238-40. PMID 14962356 DOI: 10.1179/135100003225002826 |
0.353 |
|
| 2003 |
Bull TM, Golpon H, Hebbel RP, Solovey A, Cool CD, Tuder RM, Geraci MW, Voelkel NF. Circulating endothelial cells in pulmonary hypertension. Thrombosis and Haemostasis. 90: 698-703. PMID 14515191 DOI: 10.1160/Th03-04-0251 |
0.336 |
|
| 2003 |
Shet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP. Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood. 102: 2678-83. PMID 12805058 DOI: 10.1182/Blood-2003-03-0693 |
0.403 |
|
| 2003 |
Lamming CE, Augustin L, Blackstad M, Lund TC, Hebbel RP, Verfaillie CM. Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis. The Journal of Clinical Investigation. 111: 811-9. PMID 12639987 DOI: 10.1172/Jci15956 |
0.347 |
|
| 2003 |
Belcher JD, Bryant CJ, Nguyen J, Bowlin PR, Kielbik MC, Bischof JC, Hebbel RP, Vercellotti GM. Transgenic sickle mice have vascular inflammation. Blood. 101: 3953-9. PMID 12543857 DOI: 10.1182/Blood-2002-10-3313 |
0.407 |
|
| 2002 |
Burger PE, Coetzee S, McKeehan WL, Kan M, Cook P, Fan Y, Suda T, Hebbel RP, Novitzky N, Muller WA, Wilson EL. Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells. Blood. 100: 3527-35. PMID 12411316 DOI: 10.1182/Blood.V100.10.3527 |
0.384 |
|
| 2002 |
Lin Y, Chang L, Solovey A, Healey JF, Lollar P, Hebbel RP. Use of blood outgrowth endothelial cells for gene therapy for hemophilia A. Blood. 99: 457-62. PMID 11781225 DOI: 10.1182/Blood.V99.2.457 |
0.403 |
|
| 2001 |
Solovey A, Gui L, Chang L, Enenstein J, Browne PV, Hebbel RP. Identification and functional assessment of endothelial P1H12 Journal of Laboratory and Clinical Medicine. 138: 322-331. PMID 11709656 DOI: 10.1067/Mlc.2001.118519 |
0.331 |
|
| 2001 |
Stevens T, Rosenberg R, Aird W, Quertermous T, Johnson FL, Garcia JG, Hebbel RP, Tuder RM, Garfinkel S. NHLBI workshop report: endothelial cell phenotypes in heart, lung, and blood diseases. American Journal of Physiology. Cell Physiology. 281: C1422-33. PMID 11600404 DOI: 10.1152/Ajpcell.2001.281.5.C1422 |
0.401 |
|
| 2001 |
Solovey AA, Solovey AN, Harkness J, Hebbel RP. Modulation of endothelial cell activation in sickle cell disease: a pilot study Blood. 97: 1937-1941. PMID 11264155 DOI: 10.1182/Blood.V97.7.1937 |
0.455 |
|
| 2001 |
Nath KA, Grande JP, Haggard JJ, Croatt AJ, Katusic ZS, Solovey A, Hebbel RP. Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. American Journal of Pathology. 158: 893-903. PMID 11238038 DOI: 10.1016/S0002-9440(10)64037-0 |
0.392 |
|
| 2001 |
Ozcan M, Morton CT, Solovey A, Dandelet L, Bach RR, Hebbel RP, Slungaard A, Key NS. Whole blood tissue factor procoagulant activity remains detectable during severe aplasia following bone marrow and peripheral blood stem cell transplantation. Thrombosis and Haemostasis. 85: 250-255. DOI: 10.1055/S-0037-1615705 |
0.313 |
|
| 2000 |
Nath KA, Shah V, Haggard JJ, Croatt AJ, Smith LA, Hebbel RP, Katusic ZS. Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 279. PMID 11080057 DOI: 10.1152/Ajpregu.2000.279.6.R1949 |
0.366 |
|
| 2000 |
Niihara Y, Shalev O, Hebbel RP, Wu H, Tu A, Akiyama DS, Tanaka KR. Desferrioxamine (DFO) conjugated with starch decreases NAD redox potential of intact red blood cells (RBC): evidence for DFO as an extracellular inducer of oxidant stress in RBC. American Journal of Hematology. 65: 281-4. PMID 11074553 DOI: 10.1002/1096-8652(200012)65:4<281::Aid-Ajh3>3.0.Co;2-K |
0.35 |
|
| 2000 |
Kaul DK, Hebbel RP. Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice Journal of Clinical Investigation. 106: 411-420. PMID 10930444 DOI: 10.1172/Jci9225 |
0.397 |
|
| 2000 |
Hebbel RP. Blockade of Adhesion of Sickle Cells to Endothelium by Monoclonal Antibodies The New England Journal of Medicine. 342: 1910-1912. PMID 10861330 DOI: 10.1056/Nejm200006223422512 |
0.36 |
|
| 2000 |
Lin Y, Weisdorf DJ, Solovey A, Hebbel RP. Origins of circulating endothelial cells and endothelial outgrowth from blood. Journal of Clinical Investigation. 105: 71-77. PMID 10619863 DOI: 10.1172/Jci8071 |
0.391 |
|
| 2000 |
Belcher JD, Marker PH, Weber JP, Hebbel RP, Vercellotti GM. Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion Blood. 96: 2451-2459. DOI: 10.1182/Blood.V96.7.2451.H8002451_2451_2459 |
0.444 |
|
| 2000 |
Osarogiagbon UR, Choong S, Belcher JD, Vercellotti GM, Paller MS, Hebbel RP. Reperfusion injury pathophysiology in sickle transgenic mice Blood. 96: 314-320. DOI: 10.1182/Blood.V96.1.314 |
0.354 |
|
| 1999 |
Gupta K, Gupta P, Wild R, Ramakrishnan S, Hebbel RP. Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis. 3: 147-158. PMID 14517432 DOI: 10.1023/A:1009018702832 |
0.364 |
|
| 1999 |
de Franceschi L, Shalev O, Piga A, Collell M, Olivieri O, Corrocher R, Hebbel RP, Brugnara C. Deferiprone therapy in homozygous human beta-thalassemia removes erythrocyte membrane free iron and reduces KCl cotransport activity. The Journal of Laboratory and Clinical Medicine. 133: 64-9. PMID 10385483 DOI: 10.1053/Lc.1999.V133.A94241 |
0.338 |
|
| 1999 |
Belcher JD, Marker PH, Geiger P, Girotti AW, Steinberg MH, Hebbel RP, Vercellotti GM. Low-density lipoprotein susceptibility to oxidation and cytotoxicity to endothelium in sickle cell anemia Journal of Laboratory and Clinical Medicine. 133: 605-612. PMID 10360636 DOI: 10.1016/S0022-2143(99)90191-9 |
0.338 |
|
| 1999 |
Gupta K, Kshirsagar S, Li W, Gui L, Ramakrishnan S, Gupta P, Law P, Hebbel RP. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Experimental Cell Research. 247: 495-504. PMID 10066377 DOI: 10.1006/Excr.1998.4359 |
0.376 |
|
| 1999 |
Gupta K, Gupta P, Solovey A, Hebbel RP. Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin. Biochimica Et Biophysica Acta. 1453: 63-73. PMID 9989246 DOI: 10.1016/S0925-4439(98)00085-4 |
0.34 |
|
| 1999 |
Solovey A, Gui L, Ramakrishnan S, Steinberg MH, Hebbel RP. Sickle Cell Anemia as a Possible State of Enhanced Anti-Apoptotic Tone: Survival Effect of Vascular Endothelial Growth Factor on Circulating and Unanchored Endothelial Cells Blood. 93: 3824-3830. DOI: 10.1182/Blood.V93.11.3824.411K10_3824_3830 |
0.408 |
|
| 1998 |
Browne P, Shalev O, Hebbel RP. The molecular pathobiology of cell membrane iron: the sickle red cell as a model. Free Radical Biology & Medicine. 24: 1040-8. PMID 9607615 DOI: 10.1016/S0891-5849(97)00391-2 |
0.3 |
|
| 1998 |
Solovey A, Gui L, Key NS, Hebbel RP. Tissue factor expression by endothelial cells in sickle cell anemia. The Journal of Clinical Investigation. 101: 1899-904. PMID 9576754 DOI: 10.1172/Jci1932 |
0.408 |
|
| 1998 |
Nath KA, Grande JP, Croatt AJ, Likely S, Hebbel RP, Enright H. Intracellular targets in heme protein-induced renal injury Kidney International. 53: 100-111. PMID 9453005 DOI: 10.1046/J.1523-1755.1998.00731.X |
0.315 |
|
| 1998 |
Sheng K, Shariff M, Hebbel RP. Comparative oxidation of hemoglobins A and S. Blood. 91: 3467-3470. DOI: 10.1182/Blood.V91.9.3467.3467_3467_3470 |
0.308 |
|
| 1997 |
Solovey A, Lin Y, Browne P, Choong S, Wayner E, Hebbel RP. Circulating Activated Endothelial Cells in Sickle Cell Anemia The New England Journal of Medicine. 337: 1584-1590. PMID 9371854 DOI: 10.1056/Nejm199711273372203 |
0.43 |
|
| 1997 |
Browne PV, Shalev O, Kuypers FA, Brugnara C, Solovey A, Mohandas N, Schrier SL, Hebbel RP. Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia. The Journal of Clinical Investigation. 100: 1459-64. PMID 9294111 DOI: 10.1172/Jci119666 |
0.316 |
|
| 1997 |
Gupta K, Ramakrishnan S, Browne PV, Solovey A, Hebbel RP. A novel technique for culture of human dermal microvascular endothelial cells under either serum-free or serum-supplemented conditions: isolation by panning and stimulation with vascular endothelial growth factor. Experimental Cell Research. 230: 244-251. PMID 9024783 DOI: 10.1006/Excr.1996.3421 |
0.4 |
|
| 1997 |
Barabino GA, Wise RJ, Woodbury VA, Zhang B, Bridges KA, Hebbel RP, Lawler J, Ewenstein BM. Inhibition of Sickle Erythrocyte Adhesion to Immobilized Thrombospondin by von Willebrand Factor Under Dynamic Flow Conditions Blood. 89: 2560-2567. DOI: 10.1182/Blood.V89.7.2560 |
0.41 |
|
| 1996 |
Browne PV, Hebbel RP. CD36-positive stress reticulocytosis in sicle cell anemia Journal of Laboratory and Clinical Medicine. 127: 340-347. PMID 8656036 DOI: 10.1016/S0022-2143(96)90181-X |
0.31 |
|
| 1996 |
Browne PV, Mosher DF, Steinberg MH, Hebbel RP. Disturbance of plasma and platelet thrombospondin levels in sickle cell disease American Journal of Hematology. 51: 296-301. PMID 8602630 DOI: 10.1002/(Sici)1096-8652(199604)51:4<296::Aid-Ajh8>3.0.Co;2-R |
0.324 |
|
| 1996 |
Shalev O, Hebbel RP. Catalysis of soluble hemoglobin oxidation by free iron on sickle red cell membranes Blood. 87: 3948-3952. DOI: 10.1182/Blood.V87.9.3948.Bloodjournal8793948 |
0.304 |
|
| 1994 |
Marva E, Hebbel RP. Denaturing interaction between sickle hemoglobin and phosphatidylserine liposomes Blood. 83: 242-249. DOI: 10.1182/Blood.V83.1.242.Bloodjournal831242 |
0.303 |
|
| 1993 |
Sugihara T, Rao G, Hebbel RP. Diphenylamine : an unusual antioxidant Free Radical Biology and Medicine. 14: 381-387. PMID 8468023 DOI: 10.1016/0891-5849(93)90087-B |
0.304 |
|
| 1992 |
Sugihara T, Repka T, Hebbel RP. Detection, characterization, and bioavailability of membrane-associated iron in the intact sickle red cell Journal of Clinical Investigation. 90: 2327-2332. PMID 1469090 DOI: 10.1172/Jci116121 |
0.317 |
|
| 1992 |
Sugihara K, Hebbel RP. Multiple mechanisms of sickle erythrocyte adherence to vascular endothelial cells Clinical Hemorheology and Microcirculation. 12: 185-189. DOI: 10.3233/Ch-1992-12203 |
0.404 |
|
| 1992 |
Sugihara T, Hebbel RP. Exaggerated cation leak from oxygenated sickle red blood cells during deformation: evidence for a unique leak pathway. Blood. 80: 2374-2378. DOI: 10.1182/Blood.V80.9.2374.Bloodjournal8092374 |
0.307 |
|
| 1992 |
Sugihara K, Sugihara T, Mohandas N, Hebbel R. Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells Blood. 80: 2634-2642. DOI: 10.1182/Blood.V80.10.2634.Bloodjournal80102634 |
0.368 |
|
| 1991 |
Hebbel RP, Mohandas N. Reversible deformation-dependent erythrocyte cation leak. Extreme sensitivity conferred by minimal peroxidation. Biophysical Journal. 60: 712-715. PMID 1932555 DOI: 10.1016/S0006-3495(91)82100-2 |
0.327 |
|
| 1991 |
Hebbel RP. Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology. Blood. 77: 214-237. DOI: 10.1182/Blood.V77.2.214.Bloodjournal772214 |
0.301 |
|
| 1991 |
Sugihara T, Rawicz W, Evans EA, Hebbel RP. Lipid hydroperoxides permit deformation-dependent leak of monovalent cation from erythrocytes. Blood. 77: 2757-2763. DOI: 10.1182/Blood.V77.12.2757.Bloodjournal77122757 |
0.306 |
|
| 1990 |
Ney PA, Christopher MM, Hebbel RP. Synergistic effects of oxidation and deformation on erythrocyte monovalent cation leak Blood. 75: 1192-1198. DOI: 10.1182/Blood.V75.5.1192.1192 |
0.312 |
|
| 1989 |
Hebbel RP, Ney PA, Foker W. Autoxidation, dehydration, and adhesivity may be related abnormalities of sickle erythrocytes American Journal of Physiology - Cell Physiology. 256. PMID 2923193 DOI: 10.1152/Ajpcell.1989.256.3.C579 |
0.395 |
|
| 1988 |
Hebbel RP, Miller WJ. Unique promotion of erythrophagocytosis by malondialdehyde. American Journal of Hematology. 29: 222-225. PMID 3189319 DOI: 10.1002/Ajh.2830290409 |
0.323 |
|
| 1987 |
Smith CM, Hebbel RP, Tukey DP, Clawson CC, White JG, Vercellotti GM. Pluronic F-68 reduces the endothelial adherence and improves the rheology of liganded sickle erythrocytes. Blood. 69: 1631-1636. DOI: 10.1182/Blood.V69.6.1631.1631 |
0.396 |
|
| 1984 |
Hebbel RP, Miller WJ. Phagocytosis of sickle erythrocytes: immunologic and oxidative determinants of hemolytic anemia Blood. 64: 733-741. DOI: 10.1182/Blood.V64.3.733.Bloodjournal643733 |
0.374 |
|
| 1984 |
Hebbel RP. Erythrocyte autooxidation in sickle cell anemia Trends in Pharmacological Sciences. 5: 371-372. DOI: 10.1016/0165-6147(84)90473-5 |
0.332 |
|
| 1981 |
Shalev O, Leida MN, Hebbel RP, Jacob HS, Eaton JW. Abnormal erythrocyte calcium homeostasis in oxidant-induced hemolytic disease. Blood. 58: 1232-1235. DOI: 10.1182/Blood.V58.6.1232.1232 |
0.348 |
|
| 1981 |
Hebbel R, Moldow C, Steinberg M. Modulation of erythrocyte-endothelial interactions and the vasocclusive severity of sickling disorders Blood. 58: 947-952. DOI: 10.1182/Blood.V58.5.947.947 |
0.368 |
|
| 1980 |
Hebbel RP, Boogaerts MAB, Eaton JW, Steinberg MH. Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity. The New England Journal of Medicine. 302: 992-995. PMID 7366623 DOI: 10.1056/Nejm198005013021803 |
0.39 |
|
| 1980 |
Hebbel RP, Yamada O, Moldow CF, Jacob HS, White JG, Eaton JW. Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease. The Journal of Clinical Investigation. 65: 154-60. PMID 7350195 DOI: 10.1172/Jci109646 |
0.439 |
|
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