| Year |
Citation |
Score |
| 2024 |
Wei J, Huang CS, Shen Y, Sadre-Bazzaz K, Tong L. Sample optimizations to enable the structure determination of biotin-dependent carboxylases. Methods in Enzymology. 708: 31-43. PMID 39572145 DOI: 10.1016/bs.mie.2024.10.001 |
0.315 |
|
| 2022 |
López-Alonso JP, Lázaro M, Gil-Cartón D, Choi PH, Tong L, Valle M. CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase. Nature Communications. 13: 6185. PMID 36261450 DOI: 10.1038/s41467-022-33987-2 |
0.331 |
|
| 2021 |
Ranjan B, Choi PH, Pillai S, Permaul K, Tong L, Singh S. Crystal structure of a thermophilic fungal cyanase and its implications on the catalytic mechanism for bioremediation. Scientific Reports. 11: 277. PMID 33431973 DOI: 10.1038/s41598-020-79489-3 |
0.402 |
|
| 2021 |
Luo S, Tong L. Structure and Function of the Separase-Securin Complex. Sub-Cellular Biochemistry. 96: 217-232. PMID 33252730 DOI: 10.1007/978-3-030-58971-4_4 |
0.306 |
|
| 2020 |
Van Drie JH, Tong L. Cryo-EM as a powerful tool for drug discovery. Bioorganic & Medicinal Chemistry Letters. 30: 127524. PMID 32890683 DOI: 10.1016/J.Bmcl.2020.127524 |
0.326 |
|
| 2020 |
Peterson BN, Young MKM, Luo S, Wang J, Whiteley AT, Woodward JJ, Tong L, Wang JD, Portnoy DA. (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes. Mbio. 11. PMID 32843560 DOI: 10.1128/Mbio.01625-20 |
0.351 |
|
| 2020 |
Yang XC, Sun Y, Aik WS, Marzluff WF, Tong L, Dominski Z. Studies with recombinant U7 snRNP demonstrate that CPSF73 is both an endonuclease and a 5'-3' exonuclease. Rna (New York, N.Y.). PMID 32554553 DOI: 10.1261/Rna.076273.120 |
0.358 |
|
| 2020 |
Sharma S, Grudzien-Nogalska E, Hamilton K, Jiao X, Yang J, Tong L, Kiledjian M. Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs. Nucleic Acids Research. PMID 32432673 DOI: 10.1093/Nar/Gkaa402 |
0.394 |
|
| 2020 |
Doamekpor SK, Grudzien-Nogalska E, Mlynarska-Cieslak A, Kowalska J, Kiledjian M, Tong L. DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. Nucleic Acids Research. PMID 32374864 DOI: 10.1093/Nar/Gkaa297 |
0.39 |
|
| 2020 |
Sun Y, Zhang Y, Aik WS, Yang XC, Marzluff WF, Walz T, Dominski Z, Tong L. Structure of an active human histone pre-mRNA 3'-end processing machinery. Science (New York, N.Y.). 367: 700-703. PMID 32029631 DOI: 10.1126/Science.Aaz7758 |
0.347 |
|
| 2020 |
Jernigan RJ, Nagaratnam N, Thifault D, Delker S, Zacks M, Edwards T, Sambucetti L, Tong L, Fromme R, Schneider J, Hsieh J, Mroczkowski B, Flint A, Fromme P, Garcia JM. New Structural Insights into the Function of the Active Full Length Human Taspase1: A Novel Anticancer Therapeutic Target Biophysical Journal. 118: 42a. DOI: 10.1016/J.Bpj.2019.11.410 |
0.327 |
|
| 2019 |
Bucholc K, Aik WS, Yang XC, Wang K, Zhou ZH, Dadlez M, Marzluff WF, Tong L, Dominski Z. Composition and processing activity of a semi-recombinant holo U7 snRNP. Nucleic Acids Research. PMID 31819999 DOI: 10.1093/Nar/Gkz1148 |
0.3 |
|
| 2019 |
Zhang Y, Sun Y, Shi Y, Walz T, Tong L. Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery. Molecular Cell. PMID 31810758 DOI: 10.1016/J.Molcel.2019.11.005 |
0.327 |
|
| 2019 |
Grime GW, Zeldin O, Snell ME, Lowe ED, Hunt JF, Montelione GT, Tong L, Snell EH, Garman EF. High-throughput PIXE as an essential quantitative assay for accurate metalloprotein structural analysis; development and application. Journal of the American Chemical Society. PMID 31794207 DOI: 10.2210/Pdb6Oe2/Pdb |
0.322 |
|
| 2019 |
Doamekpor SK, Gozdek A, Kwasnik A, Kufel J, Tong L. A novel 5'-hydroxyl dinucleotide hydrolase activity for the DXO/Rai1 family of enzymes. Nucleic Acids Research. PMID 31777937 DOI: 10.1093/Nar/Gkz1107 |
0.334 |
|
| 2019 |
Hamilton K, Sun Y, Tong L. Biophysical characterizations of the recognition of the AAUAAA polyadenylation signal. Rna (New York, N.Y.). PMID 31462423 DOI: 10.1261/Rna.070870.119 |
0.328 |
|
| 2019 |
Zhang Y, Chun Y, Buratowski S, Tong L. Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1. Structure (London, England : 1993). PMID 31104813 DOI: 10.2210/Pdb6O3Y/Pdb |
0.338 |
|
| 2019 |
Grudzien-Nogalska E, Wu Y, Jiao X, Cui H, Mateyak MK, Hart RP, Tong L, Kiledjian M. Structural and mechanistic basis of mammalian Nudt12 RNA deNADding. Nature Chemical Biology. 15: 575-582. PMID 31101919 DOI: 10.1038/S41589-019-0293-7 |
0.387 |
|
| 2019 |
Kwasnik A, Wang VY, Krzyszton M, Gozdek A, Zakrzewska-Placzek M, Stepniak K, Poznanski J, Tong L, Kufel J. Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity. Nucleic Acids Research. PMID 30949699 DOI: 10.1093/Nar/Gkz100 |
0.626 |
|
| 2019 |
Kwasnik A, Wang VY, Krzyszton M, Gozdek A, Zakrzewska-Placzek M, Stepniak K, Poznanski J, Tong L, Kufel J. Arabidopsis DXO1 links RNA turnover and chloroplast function independently of its enzymatic activity. Nucleic Acids Research. PMID 30949693 DOI: 10.1093/nar/gkz257 |
0.578 |
|
| 2019 |
Wei J, Leit S, Kuai J, Therrien E, Rafi S, Harwood HJ, DeLaBarre B, Tong L. An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature. PMID 30944472 DOI: 10.1038/S41586-019-1094-6 |
0.411 |
|
| 2019 |
Wei J, Leit S, Kuai J, Therrien E, Rafi S, Harwood Jr HJ, DeLaBarre B, Tong L. Cryo-EM structure of human ATP-citrate lyase in complex with a potent inhibitor Acta Crystallographica Section a Foundations and Advances. 75: a371-a371. DOI: 10.1107/S0108767319096387 |
0.362 |
|
| 2019 |
Garcia JM, Nagaratnam N, Jernigan R, Ketawala G, Delker S, Edwards T, Mendez D, Li C, Zatsepin N, Fromme R, Tong L, Schneider J, Hsieh J, Flint A, Fromme P. Structure Determination of Active Full Length Human Taspase1: Towards Novel Anti-Cancer Therapeutics Biophysical Journal. 116: 17a. DOI: 10.1016/J.Bpj.2018.11.135 |
0.302 |
|
| 2018 |
Luo S, Xu K, Xiang S, Chen J, Chen C, Guo C, Tong Y, Tong L. High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form. Acta Crystallographica. Section F, Structural Biology Communications. 74: 717-724. PMID 30387777 DOI: 10.1107/S2053230X18012955 |
0.45 |
|
| 2018 |
Yun JS, Yoon JH, Choi YJ, Son YJ, Kim S, Tong L, Chang JH. Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate. Biochemical and Biophysical Research Communications. PMID 30180947 DOI: 10.1016/J.Bbrc.2018.08.135 |
0.435 |
|
| 2018 |
Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Ambesi-Impiombato A, Sánchez-Martín M, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando AA. Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell. 34: 136-147.e6. PMID 29990496 DOI: 10.1016/J.Ccell.2018.06.003 |
0.324 |
|
| 2018 |
Albrecht TR, Shevtsov SP, Wu Y, Mascibroda LG, Peart NJ, Huang KL, Sawyer IA, Tong L, Dundr M, Wagner EJ. Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module. Nucleic Acids Research. PMID 29471365 DOI: 10.1093/Nar/Gky100 |
0.362 |
|
| 2018 |
Luo S, Tong L. Structural biology of the separase-securin complex with crucial roles in chromosome segregation. Current Opinion in Structural Biology. 49: 114-122. PMID 29452922 DOI: 10.1016/J.Sbi.2018.01.012 |
0.393 |
|
| 2017 |
Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, ... ... Tong L, et al. Expression system for structural and functional studies of human glycosylation enzymes. Nature Chemical Biology. PMID 29251719 DOI: 10.1038/Nchembio.2539 |
0.396 |
|
| 2017 |
Sun Y, Zhang Y, Hamilton K, Manley JL, Shi Y, Walz T, Tong L. Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proceedings of the National Academy of Sciences of the United States of America. PMID 29208711 DOI: 10.1073/Pnas.1718723115 |
0.304 |
|
| 2017 |
Aik WS, Lin MH, Tan D, Tripathy A, Marzluff WF, Dominski Z, Chou CY, Tong L. The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing. Plos One. 12: e0186034. PMID 29020104 DOI: 10.1371/Journal.Pone.0186034 |
0.57 |
|
| 2017 |
Choi PH, Vu TMN, Pham HT, Woodward JJ, Turner MS, Tong L. Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808024 DOI: 10.1073/Pnas.1704756114 |
0.419 |
|
| 2017 |
Maderbocus R, Fields BL, Hamilton K, Luo S, Tran TH, Dietrich LEP, Tong L. Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer. Nature Communications. 8: 160. PMID 28757619 DOI: 10.1038/S41467-017-00233-Z |
0.454 |
|
| 2017 |
Tong L. Striking Diversity in Holoenzyme Architecture and Extensive Conformational Variability in Biotin-Dependent Carboxylases. Advances in Protein Chemistry and Structural Biology. 109: 161-194. PMID 28683917 DOI: 10.1016/Bs.Apcsb.2017.04.006 |
0.444 |
|
| 2017 |
Wu Y, Albrecht TR, Baillat D, Wagner EJ, Tong L. Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396433 DOI: 10.1073/Pnas.1616605114 |
0.399 |
|
| 2017 |
McFarland AP, Luo S, Ahmed-Qadri F, Zuck M, Thayer EF, Goo YA, Hybiske K, Tong L, Woodward JJ. Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State. Immunity. 46: 433-445. PMID 28329705 DOI: 10.1016/J.Immuni.2017.02.014 |
0.314 |
|
| 2017 |
Jiao X, Doamekpor SK, Bird JG, Nickels BE, Tong L, Hart RP, Kiledjian M. 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding. Cell. 168: 1015-1027.e10. PMID 28283058 DOI: 10.1016/J.Cell.2017.02.019 |
0.303 |
|
| 2017 |
Zhang Y, Shan CM, Wang J, Bao K, Tong L, Jia S. Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Scientific Reports. 7: 43906. PMID 28256625 DOI: 10.1038/Srep43906 |
0.365 |
|
| 2017 |
Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, ... ... Tong L, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 168: 878-889.e29. PMID 28235199 DOI: 10.1016/J.Cell.2017.02.006 |
0.504 |
|
| 2017 |
Luo S, Tong L. Molecular mechanism for the regulation of yeast separase by securin. Nature. PMID 28146474 DOI: 10.1038/Nature21061 |
0.49 |
|
| 2017 |
Zhu Y, Luo S, Sabo Y, Wang C, Tong L, Goff SP. Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. Cell Host & Microbe. PMID 28132836 DOI: 10.1016/J.Chom.2017.01.002 |
0.331 |
|
| 2017 |
Li M, Zhang WK, Benvin NM, Zhou X, Su D, Li H, Wang S, Michailidis IE, Tong L, Li X, Yang J. Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nature Structural & Molecular Biology. PMID 28112729 DOI: 10.1038/Nsmb.3362 |
0.346 |
|
| 2017 |
Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L. Erratum: A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation. Cell Discovery. 3: 16055. PMID 28101377 DOI: 10.1038/celldisc.2016.55 |
0.765 |
|
| 2017 |
Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA. c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance, and osmoregulation. Molecular Microbiology. PMID 28097715 DOI: 10.1111/Mmi.13622 |
0.325 |
|
| 2017 |
Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Sanchez-Martin M, Ambesi-Impiombato A, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando A. Abstract PR02: Mechanisms of NT5C2 activating mutations driving thiopurine resistance in relapsed lymphoblastic leukemia Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Hemmal17-Pr02 |
0.362 |
|
| 2016 |
Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L. A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation. Cell Discovery. 2: 16044. PMID 27990296 DOI: 10.1038/Celldisc.2016.44 |
0.819 |
|
| 2016 |
Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Ramesh M, Espina N, Sun M, Tutuncuoglu B, Madison-Antenucci S, Woolford JL, Tong L, Frank J. Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 113: 12174-12179. PMID 27791004 DOI: 10.1073/Pnas.1614594113 |
0.384 |
|
| 2016 |
Lewis-Ballester A, Forouhar F, Kim SM, Lew S, Wang Y, Karkashon S, Seetharaman J, Batabyal D, Chiang BY, Hussain M, Correia MA, Yeh SR, Tong L. Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase. Scientific Reports. 6: 35169. PMID 27762317 DOI: 10.1038/Srep35169 |
0.429 |
|
| 2016 |
Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Espina N, Madison-Antenucci S, Tong L, Frank J. Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM. Protein Science : a Publication of the Protein Society. PMID 27750394 DOI: 10.1002/Pro.3068 |
0.32 |
|
| 2016 |
Choi PH, Jo J, Lin YC, Lin MH, Chou CY, Dietrich LE, Tong L. A distinct holoenzyme organization for two-subunit pyruvate carboxylase. Nature Communications. 7: 12713. PMID 27708276 DOI: 10.1038/Ncomms12713 |
0.427 |
|
| 2016 |
Shan CM, Wang J, Xu K, Chen H, Yue JX, Andrews S, Moresco JJ, Yates JR, Nagy PL, Tong L, Jia S. A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife. 5. PMID 27648579 DOI: 10.7554/Elife.17903 |
0.304 |
|
| 2016 |
Zhang Y, Rataj K, Simpson GG, Tong L. Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA. Plos One. 11: e0160694. PMID 27513867 DOI: 10.1371/Journal.Pone.0160694 |
0.419 |
|
| 2016 |
Huynh TN, Choi PH, Sureka K, Ledvina HE, Campillo J, Tong L, Woodward JJ. Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC. Molecular Microbiology. PMID 27378384 DOI: 10.1111/Mmi.13456 |
0.334 |
|
| 2016 |
Sansó M, Levin RS, Lipp JJ, Wang VY, Greifenberg AK, Quezada EM, Ali A, Ghosh A, Larochelle S, Rana TM, Geyer M, Tong L, Shokat KM, Fisher RP. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes & Development. 30: 117-31. PMID 26728557 DOI: 10.1101/Gad.269589.115 |
0.649 |
|
| 2015 |
Jurado AR, Huang CS, Zhang X, Zhou ZH, Tong L. Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. Nature Communications. 6: 8986. PMID 26593090 DOI: 10.1038/Ncomms9986 |
0.58 |
|
| 2015 |
Wei J, Tong L. Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature. 526: 723-7. PMID 26458104 DOI: 10.1038/Nature15375 |
0.473 |
|
| 2015 |
Everett J, Tejero R, Murthy SB, Acton TB, Aramini JM, Baran MC, Benach J, Cort JR, Eletsky A, Forouhar F, Guan R, Kuzin AP, Lee HW, Liu G, Mani R, ... ... Tong L, et al. A Community Resource of Experimental Data for NMR - X-ray Crystal Structure Pairs. Protein Science : a Publication of the Protein Society. PMID 26293815 DOI: 10.1002/Pro.2774 |
0.335 |
|
| 2015 |
Mompeán M, Hervás R, Xu Y, Tran TH, Guarnaccia C, Buratti E, Baralle F, Tong L, Carrión-Vázquez M, McDermott AE, Laurents DV. Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43. The Journal of Physical Chemistry Letters. 6: 2608-15. PMID 26266742 DOI: 10.1021/Acs.Jpclett.5B00918 |
0.323 |
|
| 2015 |
Aramini JM, Vorobiev SM, Tuberty LM, Janjua H, Campbell ET, Seetharaman J, Su M, Huang YJ, Acton TB, Xiao R, Tong L, Montelione GT. The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS. Structure (London, England : 1993). 23: 1382-93. PMID 26165597 DOI: 10.1016/J.Str.2015.06.003 |
0.401 |
|
| 2015 |
Wang VY, Jiao X, Kiledjian M, Tong L. Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Research. PMID 26101253 DOI: 10.1093/Nar/Gkv620 |
0.689 |
|
| 2015 |
Webb BA, Forouhar F, Szu FE, Seetharaman J, Tong L, Barber DL. Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature. PMID 25985179 DOI: 10.1038/Nature14405 |
0.42 |
|
| 2015 |
Huynh TN, Luo S, Pensinger D, Sauer JD, Tong L, Woodward JJ. An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proceedings of the National Academy of Sciences of the United States of America. 112: E747-56. PMID 25583510 DOI: 10.1073/Pnas.1416485112 |
0.319 |
|
| 2015 |
Tran TH, Hsiao YS, Jo J, Chou CY, Dietrich LE, Walz T, Tong L. Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase. Nature. 518: 120-4. PMID 25383525 DOI: 10.1038/Nature13912 |
0.652 |
|
| 2014 |
Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-Sánchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, ... ... Tong L, et al. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 111: E4697-705. PMID 25339443 DOI: 10.1073/Pnas.1413128111 |
0.416 |
|
| 2014 |
Sureka K, Choi PH, Precit M, Delince M, Pensinger DA, Huynh TN, Jurado AR, Goo YA, Sadilek M, Iavarone AT, Sauer JD, Tong L, Woodward JJ. The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function. Cell. 158: 1389-401. PMID 25215494 DOI: 10.1016/J.Cell.2014.07.046 |
0.353 |
|
| 2014 |
Luo S, Tong L. Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain. Proceedings of the National Academy of Sciences of the United States of America. 111: 13834-9. PMID 25201973 DOI: 10.1073/Pnas.1412742111 |
0.414 |
|
| 2014 |
Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/Cb500327M |
0.338 |
|
| 2014 |
Tan D, Zhou M, Kiledjian M, Tong L. The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. Nature Structural & Molecular Biology. 21: 679-85. PMID 25026078 DOI: 10.1038/Nsmb.2857 |
0.551 |
|
| 2014 |
Wilson WC, Hornig-Do HT, Bruni F, Chang JH, Jourdain AA, Martinou JC, Falkenberg M, Spåhr H, Larsson NG, Lewis RJ, Hewitt L, Baslé A, Cross HE, Tong L, Lebel RR, et al. A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression. Human Molecular Genetics. 23: 6345-55. PMID 25008111 DOI: 10.1093/Hmg/Ddu352 |
0.325 |
|
| 2014 |
Zhang J, Tan D, DeRose EF, Perera L, Dominski Z, Marzluff WF, Tong L, Hall TM. Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 111: E2937-46. PMID 25002523 DOI: 10.1073/Pnas.1406381111 |
0.575 |
|
| 2014 |
Lasso G, Yu LP, Gil D, Lázaro M, Tong L, Valle M. Functional conformations for pyruvate carboxylase during catalysis explored by cryoelectron microscopy. Structure (London, England : 1993). 22: 911-22. PMID 24882745 DOI: 10.1016/J.Str.2014.04.011 |
0.612 |
|
| 2014 |
Wang R, Rajagopalan K, Sadre-Bazzaz K, Moreau M, Klessig DF, Tong L. Structure of the Arabidopsis thaliana TOP2 oligopeptidase. Acta Crystallographica. Section F, Structural Biology Communications. 70: 555-9. PMID 24817709 DOI: 10.1107/S2053230X14006128 |
0.447 |
|
| 2014 |
Yang X, Xu M, Wang Y, Xia P, Wang S, Ye B, Tong L, Jiang T, Fan Z. Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae. Acta Crystallographica. Section D, Biological Crystallography. 70: 1094-103. PMID 24699653 DOI: 10.1107/S1399004714001242 |
0.42 |
|
| 2014 |
Jurado AR, Tan D, Jiao X, Kiledjian M, Tong L. Structure and function of pre-mRNA 5'-end capping quality control and 3'-end processing. Biochemistry. 53: 1882-98. PMID 24617759 DOI: 10.1021/Bi401715V |
0.558 |
|
| 2014 |
Xiang K, Tong L, Manley JL. Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery. Molecular and Cellular Biology. 34: 1894-910. PMID 24591651 DOI: 10.1128/Mcb.00084-14 |
0.346 |
|
| 2014 |
Srinivasan B, Forouhar F, Shukla A, Sampangi C, Kulkarni S, Abashidze M, Seetharaman J, Lew S, Mao L, Acton TB, Xiao R, Everett JK, Montelione GT, Tong L, Balaram H. Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. The Febs Journal. 281: 1613-28. PMID 24456211 DOI: 10.1111/Febs.12727 |
0.385 |
|
| 2014 |
Vorobiev SM, Gensler Y, Vahedian-Movahed H, Seetharaman J, Su M, Huang JY, Xiao R, Kornhaber G, Montelione GT, Tong L, Ebright RH, Nickels BE. Structure of the DNA-binding and RNA-polymerase-binding region of transcription antitermination factor λQ. Structure (London, England : 1993). 22: 488-95. PMID 24440517 DOI: 10.1016/J.Str.2013.12.010 |
0.357 |
|
| 2014 |
Bjelic S, Kipnis Y, Wang L, Pianowski Z, Vorobiev S, Su M, Seetharaman J, Xiao R, Kornhaber G, Hunt JF, Tong L, Hilvert D, Baker D. Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. Journal of Molecular Biology. 426: 256-71. PMID 24161950 DOI: 10.1016/J.Jmb.2013.10.012 |
0.308 |
|
| 2013 |
Meng L, Forouhar F, Thieker D, Gao Z, Ramiah A, Moniz H, Xiang Y, Seetharaman J, Milaninia S, Su M, Bridger R, Veillon L, Azadi P, Kornhaber G, Wells L, ... ... Tong L, et al. Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation. The Journal of Biological Chemistry. 288: 34680-98. PMID 24155237 DOI: 10.1074/Jbc.M113.519041 |
0.48 |
|
| 2013 |
Xu SY, Kuzin AP, Seetharaman J, Gutjahr A, Chan SH, Chen Y, Xiao R, Acton TB, Montelione GT, Tong L. Structure determination and biochemical characterization of a putative HNH endonuclease from Geobacter metallireducens GS-15. Plos One. 8: e72114. PMID 24039739 DOI: 10.1371/Journal.Pone.0072114 |
0.457 |
|
| 2013 |
Yang H, Zhang T, Tao Y, Wang F, Tong L, Ding J. Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Research. 41: 10573-83. PMID 24003026 DOI: 10.1093/Nar/Gkt788 |
0.385 |
|
| 2013 |
Neklesa TK, Noblin DJ, Kuzin A, Lew S, Seetharaman J, Acton TB, Kornhaber G, Xiao R, Montelione GT, Tong L, Crews CM. A bidirectional system for the dynamic small molecule control of intracellular fusion proteins. Acs Chemical Biology. 8: 2293-300. PMID 23978068 DOI: 10.1021/Cb400569K |
0.309 |
|
| 2013 |
Mills JH, Khare SD, Bolduc JM, Forouhar F, Mulligan VK, Lew S, Seetharaman J, Tong L, Stoddard BL, Baker D. Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy. Journal of the American Chemical Society. 135: 13393-9. PMID 23924187 DOI: 10.1021/Ja403503M |
0.337 |
|
| 2013 |
Catalano J, Sadre-Bazzaz K, Amodeo GA, Tong L, McDermott A. Structural evidence: a single charged residue affects substrate binding in cytochrome P450 BM-3. Biochemistry. 52: 6807-15. PMID 23829560 DOI: 10.1021/Bi4000645 |
0.807 |
|
| 2013 |
Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Computational design of a protein-based enzyme inhibitor. Journal of Molecular Biology. 425: 3563-75. PMID 23827138 DOI: 10.1016/J.Jmb.2013.06.035 |
0.36 |
|
| 2013 |
Froese DS, Forouhar F, Tran TH, Vollmar M, Kim YS, Lew S, Neely H, Seetharaman J, Shen Y, Xiao R, Acton TB, Everett JK, Cannone G, Puranik S, Savitsky P, ... ... Tong L, et al. Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure (London, England : 1993). 21: 1182-92. PMID 23791943 DOI: 10.1016/J.Str.2013.05.001 |
0.466 |
|
| 2013 |
Tan D, Crabb WM, Whitman WB, Tong L. Crystal structure of DmdD, a crotonase superfamily enzyme that catalyzes the hydration and hydrolysis of methylthioacryloyl-CoA. Plos One. 8: e63870. PMID 23704947 DOI: 10.1371/Journal.Pone.0063870 |
0.648 |
|
| 2013 |
Jiao X, Chang JH, Kilic T, Tong L, Kiledjian M. A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing. Molecular Cell. 50: 104-15. PMID 23523372 DOI: 10.1016/J.Molcel.2013.02.017 |
0.324 |
|
| 2013 |
Tan D, Marzluff WF, Dominski Z, Tong L. Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex. Science (New York, N.Y.). 339: 318-21. PMID 23329046 DOI: 10.1126/Science.1228705 |
0.58 |
|
| 2013 |
Yu LP, Chou CY, Choi PH, Tong L. Characterizing the importance of the biotin carboxylase domain dimer for Staphylococcus aureus pyruvate carboxylase catalysis. Biochemistry. 52: 488-96. PMID 23286247 DOI: 10.1021/Bi301294D |
0.63 |
|
| 2013 |
Wang L, Li Q, Wu L, Liu S, Zhang Y, Yang X, Zhu P, Zhang H, Zhang K, Lou J, Liu P, Tong L, Sun F, Fan Z. Identification of SERPINB1 as a physiological inhibitor of human granzyme H. Journal of Immunology (Baltimore, Md. : 1950). 190: 1319-30. PMID 23269243 DOI: 10.4049/Jimmunol.1202542 |
0.412 |
|
| 2013 |
Tong L. Structure and function of biotin-dependent carboxylases. Cellular and Molecular Life Sciences : Cmls. 70: 863-91. PMID 22869039 DOI: 10.1007/S00018-012-1096-0 |
0.429 |
|
| 2012 |
Chang JH, Xiang S, Tong L. Structures of 5'-3' Exoribonucleases. The Enzymes. 31: 115-29. PMID 27166443 DOI: 10.1016/B978-0-12-404740-2.00006-9 |
0.396 |
|
| 2012 |
Yu Y, Ulbrich MH, Li MH, Dobbins S, Zhang WK, Tong L, Isacoff EY, Yang J. Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nature Communications. 3: 1252. PMID 23212381 DOI: 10.1038/Ncomms2257 |
0.318 |
|
| 2012 |
Xiang K, Manley JL, Tong L. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes & Development. 26: 2265-70. PMID 23070812 DOI: 10.1101/Gad.198853.112 |
0.37 |
|
| 2012 |
Chang JH, Jiao X, Chiba K, Oh C, Martin CE, Kiledjian M, Tong L. Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nature Structural & Molecular Biology. 19: 1011-7. PMID 22961381 DOI: 10.1038/Nsmb.2381 |
0.421 |
|
| 2012 |
Richter F, Blomberg R, Khare SD, Kiss G, Kuzin AP, Smith AJ, Gallaher J, Pianowski Z, Helgeson RC, Grjasnow A, Xiao R, Seetharaman J, Su M, Vorobiev S, Lew S, ... ... Tong L, et al. Computational design of catalytic dyads and oxyanion holes for ester hydrolysis. Journal of the American Chemical Society. 134: 16197-206. PMID 22871159 DOI: 10.1021/Ja3037367 |
0.366 |
|
| 2012 |
Feldmann EA, Seetharaman J, Ramelot TA, Lew S, Zhao L, Hamilton K, Ciccosanti C, Xiao R, Acton TB, Everett JK, Tong L, Montelione GT, Kennedy MA. Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a "double wing" DNA binding motif. Journal of Structural and Functional Genomics. 13: 155-62. PMID 22865330 DOI: 10.1007/S10969-012-9140-8 |
0.397 |
|
| 2012 |
Swapna GV, Rossi P, Montelione AF, Benach J, Yu B, Abashidze M, Seetharaman J, Xiao R, Acton TB, Tong L, Montelione GT. Three structural representatives of the PF06855 protein domain family from Staphyloccocus aureus and Bacillus subtilis have SAM domain-like folds and different functions. Journal of Structural and Functional Genomics. 13: 163-70. PMID 22843344 DOI: 10.1007/S10969-012-9134-6 |
0.377 |
|
| 2012 |
Xiang K, Manley JL, Tong L. The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity. Nature Communications. 3: 946. PMID 22781759 DOI: 10.1038/Ncomms1947 |
0.44 |
|
| 2012 |
Paulson AR, Tong L. Crystal structure of the Rna14-Rna15 complex. Rna (New York, N.Y.). 18: 1154-62. PMID 22513198 DOI: 10.1261/Rna.032524.112 |
0.6 |
|
| 2012 |
Fan C, Chou CY, Tong L, Xiang S. Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction. The Journal of Biological Chemistry. 287: 9389-98. PMID 22277658 DOI: 10.1074/Jbc.M111.319475 |
0.471 |
|
| 2012 |
Huang CS, Ge P, Zhou ZH, Tong L. An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase. Nature. 481: 219-23. PMID 22158123 DOI: 10.1038/Nature10691 |
0.62 |
|
| 2012 |
Wang L, Zhang K, Wu L, Liu S, Zhang H, Zhou Q, Tong L, Sun F, Fan Z. Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif. Journal of Immunology (Baltimore, Md. : 1950). 188: 765-73. PMID 22156497 DOI: 10.4049/Jimmunol.1101381 |
0.439 |
|
| 2012 |
Wang L, Guo H, Reyes N, Lee S, Bortz E, Guo F, Sun R, Tong L, Deng H. Distinct domains in ORF52 tegument protein mediate essential functions in murine gammaherpesvirus 68 virion tegumentation and secondary envelopment. Journal of Virology. 86: 1348-57. PMID 22090138 DOI: 10.1128/Jvi.05497-11 |
0.371 |
|
| 2012 |
Vorobiev SM, Huang YJ, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers. Protein and Peptide Letters. 19: 194-7. PMID 21933118 DOI: 10.2174/092986612799080356 |
0.371 |
|
| 2012 |
Yu Y, Ulbrich MH, Dobbins S, Li M, Zhang WK, Tong L, Isacoff EY, Yang J. Molecular and Structural Mechanism of the Assembly of an Acid-Sensing Receptor/Ion Channel Complex Biophysical Journal. 102: 345a. DOI: 10.1016/J.Bpj.2011.11.1889 |
0.356 |
|
| 2011 |
Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, Rossmann MG. Structural conservation of the myoviridae phage tail sheath protein fold. Structure (London, England : 1993). 19: 1885-94. PMID 22153511 DOI: 10.1016/J.Str.2011.09.012 |
0.777 |
|
| 2011 |
Ni S, McGookey ME, Tinch SL, Jones AN, Jayaraman S, Tong L, Kennedy MA. The 1.7 Å resolution structure of At2g44920, a pentapeptide-repeat protein in the thylakoid lumen of Arabidopsis thaliana. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1480-4. PMID 22139148 DOI: 10.1107/S1744309111037432 |
0.397 |
|
| 2011 |
Forouhar F, Saadat N, Hussain M, Seetharaman J, Lee I, Janjua H, Xiao R, Shastry R, Acton TB, Montelione GT, Tong L. A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1323-7. PMID 22102225 DOI: 10.1107/S1744309111031447 |
0.432 |
|
| 2011 |
Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, ... ... Tong L, et al. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20. PMID 22020785 DOI: 10.1002/Prot.23196 |
0.394 |
|
| 2011 |
Lowery J, Szul T, Seetharaman J, Jian X, Su M, Forouhar F, Xiao R, Acton TB, Montelione GT, Lin H, Wright JW, Lee E, Holloway ZG, Randazzo PA, Tong L, et al. Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation. The Journal of Biological Chemistry. 286: 36898-906. PMID 21828055 DOI: 10.1074/Jbc.M111.230631 |
0.403 |
|
| 2011 |
Zhang H, Constantine R, Vorobiev S, Chen Y, Seetharaman J, Huang YJ, Xiao R, Montelione GT, Gerstner CD, Davis MW, Inana G, Whitby FG, Jorgensen EM, Hill CP, Tong L, et al. UNC119 is required for G protein trafficking in sensory neurons. Nature Neuroscience. 14: 874-80. PMID 21642972 DOI: 10.1038/Nn.2835 |
0.341 |
|
| 2011 |
Chou CY, Tong L. Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. The Journal of Biological Chemistry. 286: 24417-25. PMID 21592965 DOI: 10.1074/Jbc.M111.220517 |
0.438 |
|
| 2011 |
Huang KY, Amodeo GA, Tong L, McDermott A. The structure of human ubiquitin in 2-methyl-2,4-pentanediol: a new conformational switch. Protein Science : a Publication of the Protein Society. 20: 630-9. PMID 21432937 DOI: 10.1002/Pro.584 |
0.805 |
|
| 2011 |
Chang JH, Xiang S, Xiang K, Manley JL, Tong L. Structural and biochemical studies of the 5'→3' exoribonuclease Xrn1. Nature Structural & Molecular Biology. 18: 270-6. PMID 21297639 DOI: 10.1038/Nsmb.1984 |
0.455 |
|
| 2011 |
Bai Y, Srivastava SK, Chang JH, Manley JL, Tong L. Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. Molecular Cell. 41: 311-20. PMID 21292163 DOI: 10.1016/J.Molcel.2011.01.013 |
0.569 |
|
| 2011 |
Barb AW, Cort JR, Seetharaman J, Lew S, Lee HW, Acton T, Xiao R, Kennedy MA, Tong L, Montelione GT, Prestegard JH. Structures of domains I and IV from YbbR are representative of a widely distributed protein family. Protein Science : a Publication of the Protein Society. 20: 396-405. PMID 21154411 DOI: 10.1002/Pro.571 |
0.397 |
|
| 2011 |
Huang CS, Ge P, Zhou ZH, Tong L. An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature. 481: 219-223. DOI: 10.2210/Pdb3U9R/Pdb |
0.45 |
|
| 2011 |
Tong L, Khayat R. Diseases caused by papillomavirus Xpharm: the Comprehensive Pharmacology Reference. 1-2. DOI: 10.1016/B978-008055232-3.60921-3 |
0.428 |
|
| 2011 |
Tong L, Khayat R. Cytomegaloviral (CMV) disease Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60919-5 |
0.423 |
|
| 2011 |
Khayat R, Tong L. Epstein-barr virus infections Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60916-X |
0.423 |
|
| 2011 |
Khayat R, Tong L. Herpes simplex infections Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60915-8 |
0.421 |
|
| 2010 |
Forouhar F, Lew S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Structures of bacterial biosynthetic arginine decarboxylases. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1562-6. PMID 21139196 DOI: 10.1107/S1744309110040649 |
0.457 |
|
| 2010 |
Yu LP, Kim YS, Tong L. Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden. Proceedings of the National Academy of Sciences of the United States of America. 107: 22072-7. PMID 21135213 DOI: 10.1073/Pnas.1012039107 |
0.653 |
|
| 2010 |
Lasso G, Yu LP, Gil D, Xiang S, Tong L, Valle M. Cryo-EM analysis reveals new insights into the mechanism of action of pyruvate carboxylase. Structure (London, England : 1993). 18: 1300-10. PMID 20947019 DOI: 10.1016/J.Str.2010.07.008 |
0.58 |
|
| 2010 |
Xiang K, Nagaike T, Xiang S, Kilic T, Beh MM, Manley JL, Tong L. Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature. 467: 729-33. PMID 20861839 DOI: 10.1038/Nature09391 |
0.456 |
|
| 2010 |
Rudolph MJ, Amodeo GA, Tong L. An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 999-1002. PMID 20823513 DOI: 10.1107/S1744309110028265 |
0.82 |
|
| 2010 |
Jiao X, Xiang S, Oh C, Martin CE, Tong L, Kiledjian M. Identification of a quality-control mechanism for mRNA 5'-end capping. Nature. 467: 608-11. PMID 20802481 DOI: 10.1038/Nature09338 |
0.309 |
|
| 2010 |
Huang CS, Sadre-Bazzaz K, Shen Y, Deng B, Zhou ZH, Tong L. Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature. 466: 1001-5. PMID 20725044 DOI: 10.1038/Nature09302 |
0.58 |
|
| 2010 |
Amodeo GA, Momcilovic M, Carlson M, Tong L. Biochemical and functional studies on the regulation of the Saccharomyces cerevisiae AMPK homolog SNF1. Biochemical and Biophysical Research Communications. 397: 197-201. PMID 20529674 DOI: 10.1016/J.Bbrc.2010.05.083 |
0.8 |
|
| 2010 |
Corbett JW, Freeman-Cook KD, Elliott R, Vajdos F, Rajamohan F, Kohls D, Marr E, Zhang H, Tong L, Tu M, Murdande S, Doran SD, Houser JA, Song W, Jones CJ, et al. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorganic & Medicinal Chemistry Letters. 20: 2383-8. PMID 20219367 DOI: 10.1016/J.Bmcl.2009.04.091 |
0.345 |
|
| 2010 |
Seetharaman J, Neely H, Wang D, Janjua H, Cunningham K, Owens L, Xiao R, Liu J, Baran MC, Acton TB, Montelione GT, Tong L, Hunt JF. Solution NMR Structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2L33/Pdb |
0.358 |
|
| 2010 |
Li M, He L, Buraei Z, Yu Y, Tong L, Yang J. Molecular and Structural Basis of Dual Regulation of a Canonical TRP Channel by Calmodulin Biophysical Journal. 98: 343a. DOI: 10.1016/J.Bpj.2009.12.1859 |
0.307 |
|
| 2009 |
Xiang S, Callaghan MM, Watson KG, Tong L. A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim. Proceedings of the National Academy of Sciences of the United States of America. 106: 20723-7. PMID 19926852 DOI: 10.1073/Pnas.0908431106 |
0.462 |
|
| 2009 |
Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J. Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 11558-63. PMID 19556541 DOI: 10.1073/Pnas.0903684106 |
0.4 |
|
| 2009 |
Yu LP, Xiang S, Lasso G, Gil D, Valle M, Tong L. A symmetrical tetramer for S. aureus pyruvate carboxylase in complex with coenzyme A. Structure (London, England : 1993). 17: 823-32. PMID 19523900 DOI: 10.1016/J.Str.2009.04.008 |
0.656 |
|
| 2009 |
Mandel CR, Tweel B, Tong L. Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2). Biochemical and Biophysical Research Communications. 385: 630-3. PMID 19497300 DOI: 10.1016/J.Bbrc.2009.05.122 |
0.468 |
|
| 2009 |
Hsiao YS, Parker D, Ratner AJ, Prince A, Tong L. Crystal structures of respiratory pathogen neuraminidases. Biochemical and Biophysical Research Communications. 380: 467-71. PMID 19284989 DOI: 10.1016/J.Bbrc.2009.01.108 |
0.641 |
|
| 2009 |
Chou CY, Yu LP, Tong L. Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. The Journal of Biological Chemistry. 284: 11690-7. PMID 19213731 DOI: 10.1074/Jbc.M805783200 |
0.658 |
|
| 2009 |
Xiang S, Cooper-Morgan A, Jiao X, Kiledjian M, Manley JL, Tong L. Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature. 458: 784-8. PMID 19194460 DOI: 10.1038/Nature07731 |
0.374 |
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| 2009 |
Bertonati C, Punta M, Fischer M, Yachdav G, Forouhar F, Zhou W, Kuzin AP, Seetharaman J, Abashidze M, Ramelot TA, Kennedy MA, Cort JR, Belachew A, Hunt JF, Tong L, et al. Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins. 75: 760-73. PMID 19191354 DOI: 10.1002/Prot.22287 |
0.395 |
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| 2009 |
Zhao N, Guan J, Forouhar F, Tschaplinski TJ, Cheng ZM, Tong L, Chen F. Two poplar methyl salicylate esterases display comparable biochemical properties but divergent expression patterns. Phytochemistry. 70: 32-9. PMID 19136124 DOI: 10.1016/J.Phytochem.2008.11.014 |
0.303 |
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| 2009 |
Vorobiev SM, Su M, Seetharaman J, Huang YJ, Chen CX, Maglaqui M, Janjua H, Proudfoot M, Yakunin A, Xiao R, Acton TB, Montelione GT, Tong L. Crystal structure of human retinoblastoma binding protein 9. Proteins. 74: 526-9. PMID 19004028 DOI: 10.1002/Prot.22278 |
0.456 |
|
| 2008 |
Vila JA, Aramini JM, Rossi P, Kuzin A, Su M, Seetharaman J, Xiao R, Tong L, Montelione GT, Scheraga HA. Quantum chemical 13C(alpha) chemical shift calculations for protein NMR structure determination, refinement, and validation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14389-94. PMID 18787110 DOI: 10.1073/Pnas.0807105105 |
0.33 |
|
| 2008 |
Thackray SJ, Bruckmann C, Anderson JL, Campbell LP, Xiao R, Zhao L, Mowat CG, Forouhar F, Tong L, Chapman SK. Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding. Biochemistry. 47: 10677-84. PMID 18783250 DOI: 10.1021/Bi801202A |
0.409 |
|
| 2008 |
Huang YJ, Hang D, Lu LJ, Tong L, Gerstein MB, Montelione GT. Targeting the human cancer pathway protein interaction network by structural genomics. Molecular & Cellular Proteomics : McP. 7: 2048-60. PMID 18487680 DOI: 10.1074/mcp.M700550-MCP200 |
0.33 |
|
| 2008 |
Shen Y, Tong L. Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1. Biochemistry. 47: 5767-73. PMID 18452305 DOI: 10.1021/Bi800314M |
0.397 |
|
| 2008 |
Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nature Structural & Molecular Biology. 15: 295-302. PMID 18297087 DOI: 10.1038/Nsmb.1393 |
0.439 |
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| 2008 |
Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L. Molecular insights into the biosynthesis of the F420 coenzyme. The Journal of Biological Chemistry. 283: 11832-40. PMID 18252724 DOI: 10.1074/Jbc.M710352200 |
0.351 |
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| 2008 |
Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Tong L, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202 |
0.509 |
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| 2008 |
Mandel CR, Bai Y, Tong L. Protein factors in pre-mRNA 3'-end processing. Cellular and Molecular Life Sciences : Cmls. 65: 1099-122. PMID 18158581 DOI: 10.1007/S00018-007-7474-3 |
0.47 |
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| 2008 |
Tong L, Xiang S, Mandel C, Bai Y, Manley J. Structural studies of pre-mRNA 3′-end processing Acta Crystallographica Section a Foundations of Crystallography. 64: C90-C90. DOI: 10.1107/S0108767308097092 |
0.458 |
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| 2007 |
Amodeo GA, Rudolph MJ, Tong L. Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1. Nature. 449: 492-5. PMID 17851534 DOI: 10.1038/Nature06127 |
0.822 |
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| 2007 |
Mandel CR, Tong L. How to get all "A"s in polyadenylation. Structure (London, England : 1993). 15: 1024-6. PMID 17850740 DOI: 10.1016/J.Str.2007.08.002 |
0.429 |
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| 2007 |
Benach J, Wang L, Chen Y, Ho CK, Lee S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Deng H, Sun R, Tong L. Structural and functional studies of the abundant tegument protein ORF52 from murine gammaherpesvirus 68. The Journal of Biological Chemistry. 282: 31534-41. PMID 17699518 DOI: 10.1074/Jbc.M705637200 |
0.412 |
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| 2007 |
Khan JA, Xiang S, Tong L. Crystal structure of human nicotinamide riboside kinase. Structure (London, England : 1993). 15: 1005-13. PMID 17698003 DOI: 10.1016/J.Str.2007.06.017 |
0.492 |
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| 2007 |
Forouhar F, Kuzin A, Seetharaman J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, ... ... Tong L, et al. Functional insights from structural genomics Journal of Structural and Functional Genomics. 8: 37-44. PMID 17588214 DOI: 10.1007/S10969-007-9018-3 |
0.409 |
|
| 2007 |
Li J, Mao X, Dong LQ, Liu F, Tong L. Crystal structures of the BAR-PH and PTB domains of human APPL1. Structure (London, England : 1993). 15: 525-33. PMID 17502098 DOI: 10.1016/J.Str.2007.03.011 |
0.351 |
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| 2007 |
Yin C, Khan JA, Swapna GV, Ertekin A, Krug RM, Tong L, Montelione GT. Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses. The Journal of Biological Chemistry. 282: 20584-92. PMID 17475623 DOI: 10.1074/Jbc.M611619200 |
0.388 |
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| 2007 |
Khan JA, Forouhar F, Tao X, Tong L. Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opinion On Therapeutic Targets. 11: 695-705. PMID 17465726 DOI: 10.1517/14728222.11.5.695 |
0.319 |
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| 2007 |
Tao X, Tong L. Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5. Protein Science. 16: 880-886. PMID 17400920 DOI: 10.1110/Ps.062712807 |
0.423 |
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| 2007 |
Bai Y, Auperin TC, Chou CY, Chang GG, Manley JL, Tong L. Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors. Molecular Cell. 25: 863-75. PMID 17386263 DOI: 10.1016/J.Molcel.2007.01.034 |
0.555 |
|
| 2007 |
Vorobiev SM, Neely H, Seetharaman J, Ma LC, Xiao R, Acton TB, Montelione GT, Tong L. Crystal structure of AGR_C_4470p from Agrobacterium tumefaciens. Protein Science : a Publication of the Protein Society. 16: 535-8. PMID 17322535 DOI: 10.1110/Ps.062663307 |
0.414 |
|
| 2007 |
Bai Y, Auperin TC, Tong L. The use of in situ proteolysis in the crystallization of murine CstF-77. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 135-8. PMID 17277459 DOI: 10.1107/S1744309107002904 |
0.534 |
|
| 2007 |
Rudolph MJ, Amodeo GA, Iram SH, Hong SP, Pirino G, Carlson M, Tong L. Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding. Structure (London, England : 1993). 15: 65-74. PMID 17223533 DOI: 10.1016/J.Str.2006.11.014 |
0.826 |
|
| 2007 |
Forouhar F, Anderson JL, Mowat CG, Vorobiev SM, Hussain A, Abashidze M, Bruckmann C, Thackray SJ, Seetharaman J, Tucker T, Xiao R, Ma LC, Zhao L, Acton TB, Montelione GT, ... ... Tong L, et al. Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 104: 473-8. PMID 17197414 DOI: 10.1073/Pnas.0610007104 |
0.427 |
|
| 2007 |
Xiang S, Usunow G, Lange G, Busch M, Tong L. Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis Journal of Biological Chemistry. 282: 2676-2682. PMID 17135236 DOI: 10.1074/Jbc.M610235200 |
0.487 |
|
| 2007 |
Tong L, Harwood HJ. Acetyl-coenzyme A carboxylases: versatile targets for drug discovery. Journal of Cellular Biochemistry. 99: 1476-88. PMID 16983687 DOI: 10.1002/Jcb.21077 |
0.333 |
|
| 2007 |
Rossi P, Ramelot T, Ciano M, Ho C, Ma L, Xiao R, Acton T, Kennedy M, Tong L, Montelione G. Solution NMR structure of human myeloid differentiation primary response (MyD88). Northeast Structural Genomics target HR2869A Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15356 |
0.303 |
|
| 2006 |
Mandel CR, Kaneko S, Zhang H, Gebauer D, Vethantham V, Manley JL, Tong L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature. 444: 953-6. PMID 17128255 DOI: 10.1038/Nature05363 |
0.416 |
|
| 2006 |
Mandel CR, Gebauer D, Zhang H, Tong L. A serendipitous discovery that in situ proteolysis is essential for the crystallization of yeast CPSF-100 (Ydh1p). Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1041-5. PMID 17012808 DOI: 10.1107/S1744309106038152 |
0.417 |
|
| 2006 |
Hsiao YS, Jogl G, Tong L. Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates. The Journal of Biological Chemistry. 281: 28480-7. PMID 16870616 DOI: 10.1074/Jbc.M602622200 |
0.667 |
|
| 2006 |
Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kaneko Y, Kanetko Y, Wolfgang MC, Hsiao YS, Tong L, Prince A. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. The Journal of Clinical Investigation. 116: 2297-2305. PMID 16862214 DOI: 10.1172/Jci27920 |
0.548 |
|
| 2006 |
Shen Y, Chou CY, Chang GG, Tong L. Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Molecular Cell. 22: 807-18. PMID 16793549 DOI: 10.1016/J.Molcel.2006.04.026 |
0.462 |
|
| 2006 |
Khan JA, Tao X, Tong L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nature Structural & Molecular Biology. 13: 582-8. PMID 16783377 DOI: 10.1038/Nsmb1105 |
0.436 |
|
| 2006 |
Hsiao YS, Jogl G, Esser V, Tong L. Crystal structure of rat carnitine palmitoyltransferase II (CPT-II). Biochemical and Biophysical Research Communications. 346: 974-80. PMID 16781677 DOI: 10.1016/J.Bbrc.2006.06.006 |
0.623 |
|
| 2006 |
Annedi SC, Biabani F, Poduch E, Mannargudi BM, Majumder K, Wei L, Khayat R, Tong L, Kotra LP. Engineering d-amino acid containing novel protease inhibitors using catalytic site architecture. Bioorganic & Medicinal Chemistry. 14: 214-36. PMID 16198572 DOI: 10.1016/J.Bmc.2005.08.019 |
0.61 |
|
| 2005 |
Rudolph MJ, Amodeo GA, Bai Y, Tong L. Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1. Biochemical and Biophysical Research Communications. 337: 1224-8. PMID 16236260 DOI: 10.1016/J.Bbrc.2005.09.181 |
0.81 |
|
| 2005 |
Khan JA, Dunn BM, Tong L. Crystal structure of human Taspase1, a crucial protease regulating the function of MLL. Structure (London, England : 1993). 13: 1443-52. PMID 16216576 DOI: 10.1016/J.Str.2005.07.006 |
0.436 |
|
| 2005 |
Forouhar F, Lee IS, Vujcic J, Vujcic S, Shen J, Vorobiev SM, Xiao R, Acton TB, Montelione GT, Porter CW, Tong L. Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase Journal of Biological Chemistry. 280: 40328-40336. PMID 16210326 DOI: 10.1074/Jbc.M505332200 |
0.448 |
|
| 2005 |
Tong L. Acetyl-coenzyme A carboxylase: Crucial metabolic enzyme and attractive target for drug discovery Cellular and Molecular Life Sciences. 62: 1784-1803. PMID 15968460 DOI: 10.1007/S00018-005-5121-4 |
0.379 |
|
| 2005 |
Forouhar F, Yang Y, Kumar D, Chen Y, Fridman E, Park SW, Chiang Y, Acton TB, Montelione GT, Pichersky E, Klessig DF, Tong L. Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity Proceedings of the National Academy of Sciences of the United States of America. 102: 1773-1778. PMID 15668381 DOI: 10.1073/Pnas.0409227102 |
0.41 |
|
| 2005 |
Jogl G, Hsiao YS, Tong L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. The Journal of Biological Chemistry. 280: 738-44. PMID 15492013 DOI: 10.1074/Jbc.M409894200 |
0.672 |
|
| 2005 |
Zhang H, Tweel B, Li J, Tong L. Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with CP-640186. Structure (London, England : 1993). 12: 1683-91. PMID 15341732 DOI: 10.1016/J.Str.2004.07.009 |
0.402 |
|
| 2005 |
Harrop SJ, Helliwell JR, Wan TC, Kalb AJ, Tong L, Yariv J. Structure solution of a cubic crystal of concanavalin A complexed with methyl alpha-D-glucopyranoside. Acta Crystallographica. Section D, Biological Crystallography. 52: 143-55. PMID 15299735 DOI: 10.1107/S0907444995008742 |
0.374 |
|
| 2004 |
Shen Y, Volrath SL, Weatherly SC, Elich TD, Tong L. A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product. Molecular Cell. 16: 881-91. PMID 15610732 DOI: 10.1016/J.Molcel.2004.11.034 |
0.489 |
|
| 2004 |
Jogl G, Hsiao YS, Tong L. Structure and function of carnitine acyltransferases. Annals of the New York Academy of Sciences. 1033: 17-29. PMID 15591000 DOI: 10.1196/Annals.1320.002 |
0.684 |
|
| 2004 |
Gebauer D, Li J, Jogl G, Shen Y, Myszka DG, Tong L. Crystal structure of the PH-BEACH domains of human LRBA/BGL. Biochemistry. 43: 14873-80. PMID 15554694 DOI: 10.1021/Bi049498Y |
0.368 |
|
| 2004 |
Blankenfeldt W, Kuzin AP, Skarina T, Korniyenko Y, Tong L, Bayer P, Janning P, Thomashow LS, Mavrodi DV. Structure and function of the phenazine biosynthetic protein PhzF from Pseudomonas fluorescens. Proceedings of the National Academy of Sciences of the United States of America. 101: 16431-6. PMID 15545603 DOI: 10.1073/Pnas.0407371101 |
0.444 |
|
| 2004 |
Hsu WC, Hung HC, Tong L, Chang GG. Dual functional roles of ATP in the human mitochondrial malic enzyme. Biochemistry. 43: 7382-90. PMID 15182181 DOI: 10.1021/Bi049600R |
0.417 |
|
| 2004 |
Chen YH, Li MH, Zhang Y, He LL, Yamada Y, Fitzmaurice A, Shen Y, Zhang H, Tong L, Yang J. Structural basis of the α1-β subunit interaction of voltage-gated Ca2+ channels Nature. 429: 675-680. PMID 15170217 DOI: 10.1038/Nature02641 |
0.336 |
|
| 2004 |
Hsiao YS, Jogl G, Tong L. Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase. The Journal of Biological Chemistry. 279: 31584-9. PMID 15155726 DOI: 10.1074/Jbc.M403484200 |
0.672 |
|
| 2004 |
Khan JA, Brint EK, O'Neill LA, Tong L. Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL. The Journal of Biological Chemistry. 279: 31664-70. PMID 15123616 DOI: 10.1074/Jbc.M403434200 |
0.321 |
|
| 2004 |
Zhang H, Tweel B, Tong L. Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop Proceedings of the National Academy of Sciences of the United States of America. 101: 5910-5915. PMID 15079078 DOI: 10.1073/Pnas.0400891101 |
0.441 |
|
| 2004 |
Jogl G, Tong L. Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP. Biochemistry. 43: 1425-31. PMID 14769018 DOI: 10.1021/Bi035911A |
0.489 |
|
| 2004 |
Kuo CW, Hung HC, Tong L, Chang GG. Metal-Induced reversible structural interconversion of human mitochondrial NAD(P)+-dependent malic enzyme. Proteins. 54: 404-11. PMID 14747989 DOI: 10.1002/Prot.10635 |
0.424 |
|
| 2004 |
Forouhar F, Lee I, Benach J, Kulkarni K, Xiao R, Acton TB, Montelione GT, Tong L. A novel NAD-binding protein revealed by the crystal structure of 2,3-diketo-L-gulonate reductase (YiaK). The Journal of Biological Chemistry. 279: 13148-55. PMID 14718529 DOI: 10.1074/Jbc.M313580200 |
0.477 |
|
| 2004 |
Khayat R, Batra R, Bebernitz GA, Olson MW, Tong L. Characterization of the monomer-dimer equilibrium of human cytomegalovirus protease by kinetic methods. Biochemistry. 43: 316-22. PMID 14717585 DOI: 10.1021/Bi035170D |
0.615 |
|
| 2004 |
Forouhar F, Shen J, Xiao R, Acton TB, Montelione GT, Tong L. Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot. Proteins. 53: 329-32. PMID 14517985 DOI: 10.1002/Prot.10510 |
0.325 |
|
| 2004 |
Blankenfeldt W, Kuzin AP, Skarina T, Korniyenko Y, Tong L, Bayer P, Janning P, Thomashow LS, Mavrodi DV. Structure and function of phenazine-biosynthesis protein PhzF from Pseudomonas fluorescens 2-79. Proceedings of the National Academy of Sciences of the United States of America. 101: 16431-16436. DOI: 10.2210/Pdb1U1V/Pdb |
0.359 |
|
| 2003 |
Chang GG, Tong L. Structure and function of malic enzymes, a new class of oxidative decarboxylases. Biochemistry. 42: 12721-33. PMID 14596586 DOI: 10.1021/Bi035251+ |
0.501 |
|
| 2003 |
Gobin S, Thuillier L, Jogl G, Faye A, Tong L, Chi M, Bonnefont JP, Girard J, Prip-Buus C. Functional and structural basis of carnitine palmitoyltransferase 1A deficiency. The Journal of Biological Chemistry. 278: 50428-34. PMID 14517221 DOI: 10.1074/Jbc.M310130200 |
0.437 |
|
| 2003 |
Tao X, Yang Z, Tong L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure (London, England : 1993). 11: 1141-50. PMID 12962632 DOI: 10.1016/S0969-2126(03)00168-0 |
0.764 |
|
| 2003 |
Tao X, Khayat R, Christendat D, Savchenko A, Xu X, Goldsmith-Fischman S, Honig B, Edwards A, Arrowsmith CH, Tong L. Crystal structures of MTH1187 and its yeast ortholog YBL001c. Proteins. 52: 478-80. PMID 12866058 DOI: 10.1002/Prot.10443 |
0.611 |
|
| 2003 |
Tao X, Tong L. Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease. The Journal of Biological Chemistry. 278: 31372-9. PMID 12761214 DOI: 10.1074/Jbc.M304221200 |
0.441 |
|
| 2003 |
Zhang H, Yang Z, Shen Y, Tong L. Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science (New York, N.Y.). 299: 2064-7. PMID 12663926 DOI: 10.1126/Science.1081366 |
0.774 |
|
| 2003 |
Khayat R, Batra R, Qian C, Halmos T, Bailey M, Tong L. Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease. Biochemistry. 42: 885-91. PMID 12549906 DOI: 10.1021/Bi027045S |
0.651 |
|
| 2003 |
Jogl G, Tong L. Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport. Cell. 112: 113-22. PMID 12526798 DOI: 10.1016/S0092-8674(02)01228-X |
0.49 |
|
| 2003 |
Jogl G, Rozovsky S, McDermott AE, Tong L. Optimal alignment for enzymatic proton transfer: Structure of the Michaelis complex of triosephosphate isomerase at 1.2-Å resolution Proceedings of the National Academy of Sciences of the United States of America. 100: 50-55. PMID 12509510 DOI: 10.1073/Pnas.0233793100 |
0.371 |
|
| 2003 |
Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L. Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643. The Journal of Biological Chemistry. 278: 8804-8. PMID 12496312 DOI: 10.1074/Jbc.M211892200 |
0.787 |
|
| 2002 |
Tao X, Xu Y, Zheng Y, Beg AA, Tong L. An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2. Biochemical and Biophysical Research Communications. 299: 216-21. PMID 12437972 DOI: 10.1016/S0006-291X(02)02581-0 |
0.363 |
|
| 2002 |
Jogl G, Shen Y, Gebauer D, Li J, Wiegmann K, Kashkar H, Krönke M, Tong L. Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain. The Embo Journal. 21: 4785-95. PMID 12234919 DOI: 10.1093/Emboj/Cdf502 |
0.405 |
|
| 2002 |
Batra R, Christendat D, Edwards A, Arrowsmith C, Tong L. Crystal structure of MTH169, a crucial component of phosphoribosylformylglycinamidine synthetase. Proteins. 49: 285-8. PMID 12211007 DOI: 10.1002/Prot.10209 |
0.371 |
|
| 2002 |
Yang Z, Lanks CW, Tong L. Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate. Structure (London, England : 1993). 10: 951-60. PMID 12121650 DOI: 10.1016/S0969-2126(02)00788-8 |
0.776 |
|
| 2002 |
Regan J, Breitfelder S, Cirillo P, Gilmore T, Graham AG, Hickey E, Klaus B, Madwed J, Moriak M, Moss N, Pargellis C, Pav S, Proto A, Swinamer A, Tong L, et al. Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate. Journal of Medicinal Chemistry. 45: 2994-3008. PMID 12086485 DOI: 10.1021/Jm020057R |
0.379 |
|
| 2002 |
Pargellis C, Tong L, Churchill L, Cirillo PF, Gilmore T, Graham AG, Grob PM, Hickey ER, Moss N, Pav S, Regan J. Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site. Nature Structural Biology. 9: 268-72. PMID 11896401 DOI: 10.1038/Nsb770 |
0.355 |
|
| 2002 |
Yang Z, Zhang H, Hung HC, Kuo CC, Tsai LC, Yuan HS, Chou WY, Chang GG, Tong L. Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme. Protein Science : a Publication of the Protein Society. 11: 332-41. PMID 11790843 DOI: 10.1110/Ps.38002 |
0.769 |
|
| 2001 |
Rishavy MA, Yang Z, Tong L, Cleland WW. Determination of the mechanism of human malic enzyme with natural and alternate dinucleotides by isotope effects. Archives of Biochemistry and Biophysics. 396: 43-8. PMID 11716460 DOI: 10.1006/Abbi.2001.2598 |
0.723 |
|
| 2001 |
Tong L. How to take advantage of non-crystallographic symmetry in molecular replacement: 'Locked' rotation and translation functions Acta Crystallographica - Section D Biological Crystallography. 57: 1383-1389. PMID 11567149 DOI: 10.1107/S0907444901012446 |
0.351 |
|
| 2001 |
Batra R, Khayat R, Tong L. Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. Nature Structural Biology. 8: 810-7. PMID 11524687 DOI: 10.1038/Nsb0901-810 |
0.652 |
|
| 2001 |
Rozovsky S, Jogl G, Tong L, McDermott AE. Solution-state NMR investigations of triosephosphate isomerase active site loop motion: Ligand release in relation to active site loop dynamics Journal of Molecular Biology. 310: 271-280. PMID 11419952 DOI: 10.1006/Jmbi.2001.4673 |
0.342 |
|
| 2001 |
Last-Barney K, Davidson W, Cardozo M, Frye LL, Grygon CA, Hopkins JL, Jeanfavre DD, Pav S, Qian C, Stevenson JM, Tong L, Zindell R, Kelly TA. Binding site elucidation of hydantoin-based antagonists of LFA-1 using multidisciplinary technologies: evidence for the allosteric inhibition of a protein--protein interaction. Journal of the American Chemical Society. 123: 5643-50. PMID 11403595 DOI: 10.1021/Ja0104249 |
0.401 |
|
| 2001 |
Khayat R, Batra R, Massariol MJ, Lagacé L, Tong L. Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry. 40: 6344-51. PMID 11371196 DOI: 10.1021/Bi010158B |
0.651 |
|
| 2001 |
Shi D, Morizono H, Yu X, Tong L, Allewell NM, Tuchman M. Crystallization and preliminary X-ray crystallographic studies of wild-type human ornithine transcarbamylase and two naturally occurring mutants at position 277 Acta Crystallographica Section D: Biological Crystallography. 57: 719-721. PMID 11320316 DOI: 10.1107/S0907444901002803 |
0.356 |
|
| 2001 |
Shi D, Morizono H, Yu X, Tong L, Allewell NM, Tuchman M. Human ornithine transcarbamylase: Crystallographic insights into substrate recognition and conformational changes Biochemical Journal. 354: 501-509. PMID 11237854 DOI: 10.1042/0264-6021:3540501 |
0.463 |
|
| 2001 |
Batra R, Khayat R, Tong L. Structural studies of herpesvirus proteases Protein and Peptide Letters. 8: 333-342. DOI: 10.2174/0929866013409229 |
0.646 |
|
| 2000 |
Hung HC, Chang GG, Yang Z, Tong L. Slow binding of metal ions to pigeon liver malic enzyme: a general case. Biochemistry. 39: 14095-102. PMID 11087357 DOI: 10.1021/Bi001534F |
0.752 |
|
| 2000 |
Xu Y, Tao X, Shen B, Horng T, Medzhitov R, Manley JL, Tong L. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature. 408: 111-5. PMID 11081518 DOI: 10.1038/35040600 |
0.314 |
|
| 2000 |
Yang Z, Batra R, Floyd DL, Hung HC, Chang GG, Tong L. Potent and competitive inhibition of malic enzymes by lanthanide ions. Biochemical and Biophysical Research Communications. 274: 440-4. PMID 10913357 DOI: 10.1006/Bbrc.2000.3163 |
0.765 |
|
| 2000 |
Chou WY, Chang HP, Huang CH, Kuo CC, Tong L, Chang GG. Characterization of the functional role of Asp141, Asp194, and Asp464 residues in the Mn2+-L-malate binding of pigeon liver malic enzyme. Protein Science : a Publication of the Protein Society. 9: 242-51. PMID 10716176 DOI: 10.1110/Ps.9.2.242 |
0.342 |
|
| 2000 |
Yang Z, Floyd DL, Loeber G, Tong L. Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nature Structural Biology. 7: 251-7. PMID 10700286 DOI: 10.1038/73378 |
0.781 |
|
| 2000 |
Qian C, Lagacé L, Massariol M, Chabot C, Yoakim C, Déziel R, Tong L. A rational approach towards successful crystallization and crystal treatment of human cytomegalovirus protease and its inhibitor complex. Acta Crystallographica Section D-Biological Crystallography. 56: 175-180. PMID 10666597 DOI: 10.1107/S0907444999015103 |
0.374 |
|
| 1999 |
Wu H, Park YC, Ye H, Tong L. Structural studies of human TRAF2. Cold Spring Harbor Symposia On Quantitative Biology. 64: 541-550. PMID 11232331 DOI: 10.1101/Sqb.1999.64.541 |
0.327 |
|
| 1999 |
Bhargava G, Mui S, Pav S, Wu H, Loeber G, Tong L. Preliminary crystallographic studies of human mitochondrial NAD(P)(+)-dependent malic enzyme. Journal of Structural Biology. 127: 72-75. PMID 10479619 DOI: 10.1006/Jsbi.1999.4126 |
0.401 |
|
| 1999 |
Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Ghiro E, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M, Betageri R, Cardozo M, Hickey ER, Ingraham R, ... ... Tong L, et al. Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements. Journal of Medicinal Chemistry. 42: 1757-66. PMID 10346928 DOI: 10.1021/Jm980676T |
0.373 |
|
| 1999 |
Park YC, Burkitt V, Villa AR, Tong L, Wu H. Structural basis for self-association and receptor recognition of human TRAF2. Nature. 398: 533-8. PMID 10206649 DOI: 10.1038/19110 |
0.368 |
|
| 1999 |
Xu Y, Bhargava G, Wu H, Loeber G, Tong L. Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme: a new class of oxidative decarboxylases Structure. 7: 877-889. DOI: 10.1016/S0969-2126(99)80115-4 |
0.484 |
|
| 1998 |
Tong L, Qian C, Massariol MJ, Déziel R, Yoakim C, Lagacé L. Conserved mode of peptidomimetic inhibition and substrate recognition of human cytomegalovirus protease. Nature Structural Biology. 5: 819-26. PMID 9731777 DOI: 10.1038/1860 |
0.413 |
|
| 1998 |
Tong L, Warren TC, Lukas S, Schembri-King J, Betageri R, Proudfoot JR, Jakes S. Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding. Journal of Biological Chemistry. 273: 20238-20242. PMID 9685372 DOI: 10.1074/Jbc.273.32.20238 |
0.437 |
|
| 1997 |
Tong L, Rossmann MG. [34] Rotation function calculations with GLRF program. Methods in Enzymology. 276: 594-611. PMID 27799117 DOI: 10.1016/S0076-6879(97)76080-4 |
0.492 |
|
| 1997 |
Tong L, Pav S, White DM, Rogers S, Crane KM, Cywin CL, Brown ML, Pargellis CA. A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket. Nature Structural Biology. 4: 311-6. PMID 9095200 DOI: 10.1038/Nsb0497-311 |
0.423 |
|
| 1997 |
Pav S, White DM, Rogers S, Crane KM, Cywin CL, Davidson W, Hopkins J, Brown ML, Pargellis CA, Tong L. Crystallization and preliminary crystallographic analysis of recombinant human P38 MAP kinase. Protein Science : a Publication of the Protein Society. 6: 242-5. PMID 9007996 DOI: 10.1002/Pro.5560060126 |
0.34 |
|
| 1997 |
Roth GP, Emmanuel M, Tong L. Resolution and assignment of the absolute stereochemistry of a trans-2,3-diarylpyrrolidine LTB4 inhibitor intermediate Tetrahedron-Asymmetry. 8: 185-186. DOI: 10.1016/S0957-4166(96)00512-5 |
0.321 |
|
| 1996 |
Laplante SR, Tong L, Aubry N, Pav S, Jung G, Anderson PC. Several polyhydroxymonoamide renin inhibitors assume similar conformations in the unbound and renin-bound states. International Journal of Peptide and Protein Research. 48: 401-10. PMID 8956073 DOI: 10.1111/J.1399-3011.1996.Tb00858.X |
0.326 |
|
| 1996 |
Momany C, Kovari LC, Prongay AJ, Keller W, Gitti RK, Lee BM, Gorbalenya AE, Tong L, McClure J, Ehrlich LS, Summers MF, Carter C, Rossmann MG. Crystal structure of dimeric HIV-1 capsid protein. Nature Structural Biology. 3: 763-70. PMID 8784350 DOI: 10.1038/Nsb0996-763 |
0.551 |
|
| 1996 |
Tong L, Warren TC, King J, Betageri R, Rose J, Jakes S. Crystal structures of the human p56lck SH2 domain in complex with two short phosphotyrosyl peptides at 1.0 A and 1.8 A resolution. Journal of Molecular Biology. 256: 601-610. PMID 8604142 DOI: 10.1006/Jmbi.1996.0112 |
0.414 |
|
| 1996 |
Tong L, Pav S, Lamarre D, Simoneau B, Lavallée P, Jung G. Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. Journal of Biological Chemistry. 270: 29520-29524. PMID 7493993 DOI: 10.1074/Jbc.270.49.29520 |
0.312 |
|
| 1996 |
Tong L, Warren TC, King J, Betageri R, Rose J, Jakes S. Crystal structure at 1.0 Å resolution of human p56lckSH2 domain in complex with a short phosphotyrosyl peptide Acta Crystallographica Section a Foundations of Crystallography. 52: C87-C87. DOI: 10.1107/S0108767396095608 |
0.375 |
|
| 1996 |
Tong L, Qian C, Massariol M, Bonneau PR, Cordingley MG, Lagacé L. A new serine protease fold revealed by the crystal structure of human cytomegalovirus protease Acta Crystallographica Section a Foundations of Crystallography. 52: C581-C581. DOI: 10.1107/S0108767396076398 |
0.417 |
|
| 1995 |
Cornea-Hasegan MA, Zhang Z, Lynch RE, Marinescu DC, Hadfield A, Muckelbauer JK, Munshi S, Tong L, Rossmann MG. Phase refinement and extension by means of non-crystallographic symmetry averaging using parallel computers. Acta Crystallographica. Section D, Biological Crystallography. 51: 749-59. PMID 15299805 DOI: 10.1107/S0907444995001399 |
0.411 |
|
| 1995 |
Muckelbauer JK, Kremer M, Minor I, Tong L, Zlotnick A, Johnson JE, Rossmann MG. Structure determination of coxsackievirus B3 to 3.5 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 51: 871-87. PMID 15299757 DOI: 10.1107/S0907444995002253 |
0.585 |
|
| 1995 |
Tong L, Rossmann MG. Reciprocal-space molecular-replacement averaging. Acta Crystallographica. Section D, Biological Crystallography. 51: 347-53. PMID 15299302 DOI: 10.1107/S0907444994010760 |
0.426 |
|
| 1995 |
Pav S, Lubbe K, Dô F, Lamarre D, Pargellis C, Tong L. Microtube batch protein crystallization: applications to human immunodeficiency virus type 2 (HIV-2) protease and human renin. Proteins. 20: 98-102. PMID 7824526 DOI: 10.1002/Prot.340200110 |
0.37 |
|
| 1995 |
Tong L, Pav S, Mui S, Lamarre D, Yoakim C, Beaulieu P, Anderson PC. Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere. Structure (London, England : 1993). 3: 33-40. PMID 7743130 DOI: 10.1016/S0969-2126(01)00133-2 |
0.359 |
|
| 1995 |
Tong L, Pav S, Lamarre D, Pilote L, LaPlante S, Anderson PC, Jung G. High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors. Journal of Molecular Biology. 250: 211-22. PMID 7608971 DOI: 10.1006/Jmbi.1995.0372 |
0.408 |
|
| 1995 |
Proudfoot JR, Hargrave KD, Kapadia SR, Patel UR, Grozinger KG, McNeil DW, Cullen E, Cardozo M, Tong L, Kelly TA. Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. 4. 2-Substituted dipyridodiazepinones as potent inhibitors of both wild-type and cysteine-181 HIV-1 reverse transcriptase enzymes. Journal of Medicinal Chemistry. 38: 4830-8. PMID 7490732 DOI: 10.1021/Jm00024A010 |
0.337 |
|
| 1993 |
Tong L, Wengler G, Rossmann MG. Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures. Journal of Molecular Biology. 230: 228-47. PMID 8450538 DOI: 10.1006/Jmbi.1993.1139 |
0.556 |
|
| 1993 |
Tong L, Pav S, Pargellis C, Dô F, Lamarre D, Anderson PC. Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. Proceedings of the National Academy of Sciences of the United States of America. 90: 8387-91. PMID 8378311 DOI: 10.1073/Pnas.90.18.8387 |
0.311 |
|
| 1993 |
Somoza JR, Jiang F, Tong L, Kang CH, Cho JM, Kim SH. Two crystal structures of a potently sweet protein. Natural monellin at 2.75 A resolution and single-chain monellin at 1.7 A resolution. Journal of Molecular Biology. 234: 390-404. PMID 8230222 DOI: 10.1006/Jmbi.1993.1594 |
0.611 |
|
| 1993 |
Bibler JK, Kremer M, Tong L, Rossmann MG. Crystallization and characterization of coxsackievirus B3 (CVB3) Acta Crystallographica Section a Foundations of Crystallography. 49: c66-c66. DOI: 10.1107/S0108767378098098 |
0.462 |
|
| 1993 |
Tong L, Rossmann MG. Patterson-map interpretation with noncrystallographic symmetry Journal of Applied Crystallography. 26: 15-21. DOI: 10.1107/S0021889892007295 |
0.476 |
|
| 1993 |
Tong L, Cardozo M, Jones P, Adams J. Preliminary structural analysis of the mutations selected by non-nucleoside inhibitors of HIV-1 reverse transcriptase Bioorganic & Medicinal Chemistry Letters. 3: 721-726. DOI: 10.1016/S0960-894X(01)81262-2 |
0.344 |
|
| 1992 |
Privé GG, Milburn MV, Tong L, de Vos AM, Yamaizumi Z, Nishimura S, Kim SH. X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 89: 3649-53. PMID 1565661 DOI: 10.1073/Pnas.89.8.3649 |
0.728 |
|
| 1992 |
Tong L, Choi HK, Minor W, Rossmann MG. The structure determination of Sindbis virus core protein using isomorphous replacement and molecular replacement averaging between two crystal forms. Acta Crystallographica. Section a, Foundations of Crystallography. 48: 430-42. PMID 1418825 DOI: 10.1107/S0108767391014630 |
0.53 |
|
| 1992 |
Rossmann MG, McKenna R, Tong L, Xia D, Dai J, Wu H, Choi HK, Lynch RE. Molecular replacement real-space averaging Journal of Applied Crystallography. 25: 166-180. DOI: 10.1107/S002188989101141X |
0.485 |
|
| 1991 |
Choi HK, Tong L, Minor W, Dumas P, Boege U, Rossmann MG, Wengler G. Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion. Nature. 354: 37-43. PMID 1944569 DOI: 10.1038/354037A0 |
0.547 |
|
| 1991 |
Tong LA, de Vos AM, Milburn MV, Kim SH. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP. Journal of Molecular Biology. 217: 503-16. PMID 1899707 DOI: 10.1016/0022-2836(91)90753-S |
0.61 |
|
| 1990 |
Milburn MV, Tong L, deVos AM, Brünger A, Yamaizumi Z, Nishimura S, Kim SH. Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins. Science (New York, N.Y.). 247: 939-45. PMID 2406906 DOI: 10.1126/Science.2406906 |
0.604 |
|
| 1990 |
Brünger AT, Milburn MV, Tong L, deVos AM, Jancarik J, Yamaizumi Z, Nishimura S, Ohtsuka E, Kim SH. Crystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domain. Proceedings of the National Academy of Sciences of the United States of America. 87: 4849-53. PMID 2191303 DOI: 10.1073/Pnas.87.12.4849 |
0.629 |
|
| 1990 |
Tong LA, Rossmann MG. The locked rotation function. Acta Crystallographica. Section a, Foundations of Crystallography. 46: 783-92. PMID 2174243 DOI: 10.1016/0022-2836(72)90333-6 |
0.455 |
|
| 1989 |
Glaeser RM, Tong L, Kim SH. Three-dimensional reconstructions from incomplete data: interpretability of density maps at "atomic" resolution. Ultramicroscopy. 27: 307-18. PMID 2749922 DOI: 10.1016/0304-3991(89)90021-1 |
0.505 |
|
| 1989 |
Tong L, Milburn MV, de Vos AM, Kim SH. Structure of ras proteins. Science (New York, N.Y.). 245: 244. PMID 2665078 DOI: 10.1126/Science.2665078 |
0.515 |
|
| 1988 |
de Vos AM, Tong L, Milburn MV, Matias PM, Jancarik J, Noguchi S, Nishimura S, Miura K, Ohtsuka E, Kim SH. Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21. Science (New York, N.Y.). 239: 888-93. PMID 2448879 DOI: 10.1126/Science.2448879 |
0.632 |
|
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