| Year |
Citation |
Score |
| 2024 |
Solaro RJ, Goldspink PH, Wolska BM. Emerging Concepts of Mechanisms Controlling Cardiac Tension: Focus on Familial Dilated Cardiomyopathy (DCM) and Sarcomere-Directed Therapies. Biomedicines. 12. PMID 38790961 DOI: 10.3390/biomedicines12050999 |
0.373 |
|
| 2023 |
Shafaatalab S, Li AY, Jayousi F, Maaref Y, Dababneh S, Hamledari H, Baygi DH, Barszczewski T, Ruprai B, Jannati S, Nagalingam R, Cool AM, Langa P, Chiao M, Roston T, ... Solaro RJ, et al. Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C During Development. Biorxiv : the Preprint Server For Biology. PMID 37609317 DOI: 10.1101/2023.06.06.542948 |
0.41 |
|
| 2023 |
Solís C, Warren CM, Dittloff K, DiNello E, Solaro RJ, Russell B. Cardiomyocyte external mechanical unloading activates modifications of α-actinin differently from sarcomere-originated unloading. The Febs Journal. PMID 37551968 DOI: 10.1111/febs.16925 |
0.335 |
|
| 2023 |
Langa P, Shafaattalab S, Goldspink PH, Wolska BM, Fernandes AA, Tibbits GF, Solaro RJ. A perspective on Notch signalling in progression and arrhythmogenesis in familial hypertrophic and dilated cardiomyopathies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220176. PMID 37122209 DOI: 10.1098/rstb.2022.0176 |
0.304 |
|
| 2023 |
Langa P, Marszalek RJ, Warren CM, Chowdhury SK, Halas M, Batra A, Rafael-Clyke K, Bacon A, Goldspink PH, Solaro RJ, Wolska BM. Altered coronary artery function, arteriogenesis and endothelial YAP signaling in postnatal hypertrophic cardiomyopathy. Frontiers in Physiology. 14: 1136852. PMID 37064918 DOI: 10.3389/fphys.2023.1136852 |
0.304 |
|
| 2023 |
Rosas PC, Solaro RJ. Implications of S-glutathionylation of sarcomere proteins in cardiac disorders, therapies, and diagnosis. Frontiers in Cardiovascular Medicine. 9: 1060716. PMID 36762302 DOI: 10.3389/fcvm.2022.1060716 |
0.381 |
|
| 2022 |
Langa P, Wolska BM, Solaro RJ. The Hippo Signaling Pathway as a Drug Target in Familial Dilated Cardiomyopathy. International Journal of Drug Discovery and Pharmacology. 1. PMID 38818406 DOI: 10.53941/ijddp.v1i1.189 |
0.3 |
|
| 2022 |
Solís C, Thompson WC, Peña JR, McDermott-Roe C, Langa P, Warren CM, Chrzanowska M, Wolska BM, Solaro RJ, Goldspink PH. Mechano-growth factor E-domain modulates cardiac contractile function through 14-3-3 protein interactomes. Frontiers in Physiology. 13: 1028345. PMID 36467694 DOI: 10.3389/fphys.2022.1028345 |
0.318 |
|
| 2022 |
Warren CM, Halas M, Goldspink PH, Feng HZ, Herren AW, Wolska BM, de Tombe PP, Jin JP, Solaro RJ. Truncation of the N-terminus of cardiac troponin I initiates adaptive remodeling of the myocardial proteosome via phosphorylation of mechano-sensitive signaling pathways. Molecular and Cellular Biochemistry. PMID 35316461 DOI: 10.1007/s11010-022-04414-3 |
0.416 |
|
| 2022 |
Halas M, Langa P, Warren CM, Goldspink PH, Wolska BM, Solaro RJ. . Molecular Pharmacology. PMID 35236770 DOI: 10.1124/molpharm.121.000420 |
0.478 |
|
| 2021 |
Shafaattalab S, Li AY, Gunawan MG, Kim B, Jayousi F, Maaref Y, Song Z, Weiss JN, Solaro RJ, Qu Z, Tibbits GF. Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T () Variant I79N. Frontiers in Cell and Developmental Biology. 9: 787581. PMID 34977031 DOI: 10.3389/fcell.2021.787581 |
0.414 |
|
| 2021 |
Warren CM, Halas M, Feng HZ, Wolska BM, Jin JP, Solaro RJ. NH-Terminal Cleavage of Cardiac Troponin I Signals Adaptive Response to Cardiac Stressors. Journal of Cellular Signaling. 2: 162-171. PMID 34541579 |
0.475 |
|
| 2021 |
Solís C, Solaro RJ. Novel insights into sarcomere regulatory systems control of cardiac thin filament activation. The Journal of General Physiology. 153. PMID 33740037 DOI: 10.1085/jgp.202012777 |
0.405 |
|
| 2021 |
Rayani K, Seffernick J, Li AY, Davis JP, Spuches AM, Van Petegem F, Solaro RJ, Lindert S, Tibbits GF. Binding of calcium and magnesium to human cardiac Troponin C. The Journal of Biological Chemistry. 100350. PMID 33548225 DOI: 10.1016/j.jbc.2021.100350 |
0.303 |
|
| 2020 |
Yan J, Bare DJ, DeSantiago J, Zhao W, Mei Y, Chen Z, Ginsburg KS, Solaro RJ, Wolska BM, Bers DM, Chen SW, Ai X. JNK2, A Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca] Leak-Load Relationship. Circulation Research. PMID 33334123 DOI: 10.1161/CIRCRESAHA.120.318409 |
0.313 |
|
| 2020 |
Lertwanakarn T, Suntravat M, Sanchez EE, Boonhoh W, Solaro RJ, Wolska BM, Martin JL, de Tombe PP, Tachampa K. Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra () venom via an alternative method. The Journal of Venomous Animals and Toxins Including Tropical Diseases. 26: e20200005. PMID 32742278 DOI: 10.1590/1678-9199-Jvatitd-2020-0005 |
0.322 |
|
| 2020 |
Solaro CR, Solaro RJ. StatinImplications of the complex biology and micro-environment of cardiac sarcomeres in the use of high affinity troponin antibodies as serum biomarkers for cardiac disorders. Journal of Molecular and Cellular Cardiology. PMID 32442660 DOI: 10.1016/J.Yjmcc.2020.05.010 |
0.46 |
|
| 2020 |
Chowdhury SAK, Warren CM, Simon JN, Ryba DM, Batra A, Varga P, Kranias EG, Tardiff JC, Solaro RJ, Wolska BM. Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response. Frontiers in Physiology. 11: 107. PMID 32210830 DOI: 10.3389/Fphys.2020.00107 |
0.497 |
|
| 2019 |
Rosas PC, Warren CM, Creed HA, Trzeciakowski JP, Solaro RJ, Tong CW. Cardiac Myosin Binding Protein-C Phosphorylation Mitigates Age-Related Cardiac Dysfunction: Hope for Better Aging? Jacc. Basic to Translational Science. 4: 817-830. PMID 31998850 DOI: 10.1016/J.Jacbts.2019.06.003 |
0.456 |
|
| 2019 |
Ryba DM, Warren CM, Karam CN, Davis RT, Chowdhury SAK, Alvarez MG, McCann M, Liew CW, Wieczorek DF, Varga P, Solaro RJ, Wolska BM. Sphingosine-1-Phosphate Receptor Modulator, FTY720, Improves Diastolic Dysfunction and Partially Reverses Atrial Remodeling in a Tm-E180G Mouse Model Linked to Hypertrophic Cardiomyopathy. Circulation. Heart Failure. 12: e005835. PMID 31684756 DOI: 10.1161/Circheartfailure.118.005835 |
0.765 |
|
| 2019 |
Olver TD, Edwards JC, Jurrissen TJ, Veteto AB, Jones JL, Gao C, Rau C, Warren CM, Klutho PJ, Alex L, Ferreira-Nichols SC, Ivey JR, Thorne PK, McDonald KS, Krenz M, ... Solaro RJ, et al. Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. Jacc. Basic to Translational Science. 4: 404-421. PMID 31312763 DOI: 10.1016/J.Jacbts.2019.02.004 |
0.347 |
|
| 2019 |
Li KL, Methawasin M, Tanner BCW, Granzier HL, Solaro RJ, Dong WJ. Sarcomere length-dependent effects on Ca-troponin regulation in myocardium expressing compliant titin. The Journal of General Physiology. 151: 30-41. PMID 30523116 DOI: 10.1085/Jgp.201812218 |
0.509 |
|
| 2018 |
Rajan S, Jagatheesan G, Petrashevskaya N, Biesiadecki BJ, Warren CM, Riddle T, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy. The Journal of Biological Chemistry. PMID 30567734 DOI: 10.1074/Jbc.Ra118.004879 |
0.523 |
|
| 2018 |
Ghashghaee NB, Li KL, Solaro RJ, Dong WJ. Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips. Archives of Biochemistry and Biophysics. PMID 29704484 DOI: 10.1016/J.Abb.2018.04.014 |
0.448 |
|
| 2018 |
DeSantiago J, Bare DJ, Varma D, Solaro RJ, Arora R, Banach K. The Loss of p21-Activated Kinase (Pak1) Promotes Atrial Arrhythmic Activity The Role of Pak1 in Atrial Arrhythmia. Heart Rhythm. PMID 29625277 DOI: 10.1016/J.Hrthm.2018.03.041 |
0.334 |
|
| 2017 |
Karam CN, Warren CM, Henze M, Banke NH, Lewandowski ED, Solaro RJ. Peroxisome proliferator-activated receptor α expression induces alterations in cardiac myofilaments in a pressure overload model of hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00469.2016. PMID 28130336 DOI: 10.1152/Ajpheart.00469.2016 |
0.806 |
|
| 2017 |
Ryba DM, Li J, Cowan CL, Russell B, Wolska BM, Solaro RJ. Long-Term Biased β-Arrestin Signaling Improves Cardiac Structure and Function in Dilated Cardiomyopathy. Circulation. PMID 28104714 DOI: 10.1161/Circulationaha.116.024482 |
0.475 |
|
| 2016 |
Abraham DM, Davis RT, Warren CM, Mao L, Wolska BM, Solaro RJ, Rockman HA. β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911784 DOI: 10.1073/Pnas.1609308113 |
0.464 |
|
| 2016 |
Li KL, Ghashghaee NB, Solaro RJ, Dong W. Sarcomere length dependent effects on the interaction between cTnC and cTnI in skinned papillary muscle strips. Archives of Biochemistry and Biophysics. PMID 26944554 DOI: 10.1016/J.Abb.2016.02.030 |
0.431 |
|
| 2016 |
Solaro RJ. Why we need to understand the mechanics of developing cardiac sarcomeres in humans. The Journal of Physiology. 594: 255. PMID 26767884 DOI: 10.1113/Jp271706 |
0.41 |
|
| 2016 |
Li K, Solaro RJ, Dong W. Sarcomere Length Dependent Effects on Ca2+-Induced Troponin Regulation within Chemically Skinned Cardiac Muscle Fibers Biophysical Journal. 110: 465a. DOI: 10.1016/J.Bpj.2015.11.2489 |
0.495 |
|
| 2015 |
Huang CL, Solaro RJ, Ke Y, Lei M. Editorial: Ca(2+) Signaling and Heart Rhythm. Frontiers in Physiology. 6: 423. PMID 26793124 DOI: 10.3389/Fphys.2015.00423 |
0.402 |
|
| 2015 |
Warren CM, Karam CN, Wolska BM, Kobayashi T, de Tombe PP, Arteaga GM, Bos JM, Ackerman MJ, Solaro RJ. A Green Tea Catechin Normalizes the Enhanced Ca2+ Sensitivity of Myofilaments Regulated by a Hypertrophic Cardiomyopathy Associated Mutation in Human Cardiac Troponin I (K206I). Circulation. Cardiovascular Genetics. PMID 26553696 DOI: 10.1161/Circgenetics.115.001234 |
0.793 |
|
| 2015 |
Davis RT, Simon JN, Utter M, Mungai P, Alvarez MG, Chowdhury SA, Heydemann A, Ke Y, Wolska BM, Solaro RJ. Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signalling. Cardiovascular Research. 108: 335-47. PMID 26464331 DOI: 10.1093/Cvr/Cvv234 |
0.448 |
|
| 2015 |
Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1720-30. PMID 26432840 DOI: 10.1152/Ajpheart.00339.2015 |
0.525 |
|
| 2015 |
Solaro RJ. A sarcomeric protein tongue-twister: post-translation, citrullination/deimination and elimination of arginine residues. Cardiovascular Research. 108: 212-4. PMID 26392345 DOI: 10.1093/Cvr/Cvv220 |
0.521 |
|
| 2015 |
Utter MS, Ryba DM, Li BH, Wolska BM, Solaro RJ. Omecamtiv mecarbil, a cardiac myosin activator, increases Ca2+-sensitivity in myofilaments with a dilated cardiomyopathy mutant tropomyosin E54K. Journal of Cardiovascular Pharmacology. PMID 26065842 DOI: 10.1097/Fjc.0000000000000286 |
0.535 |
|
| 2015 |
Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/Cvr/Cvv162 |
0.383 |
|
| 2015 |
Utter MS, Warren CM, Solaro RJ. Impact of anesthesia and storage on posttranslational modifications of cardiac myofilament proteins. Physiological Reports. 3. PMID 25952935 DOI: 10.14814/Phy2.12393 |
0.381 |
|
| 2015 |
Wang Y, Tsui H, Bolton EL, Wang X, Huang CL, Solaro RJ, Ke Y, Lei M. Novel insights into mechanisms for Pak1-mediated regulation of cardiac Ca(2+) homeostasis. Frontiers in Physiology. 6: 76. PMID 25852566 DOI: 10.3389/Fphys.2015.00076 |
0.546 |
|
| 2015 |
Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, et al. Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function. Circulation. Heart Failure. 8: 582-94. PMID 25740839 DOI: 10.1161/Circheartfailure.114.001550 |
0.494 |
|
| 2015 |
Lei M, Wang X, Ke Y, Solaro RJ. Regulation of Ca(2+) transient by PP2A in normal and failing heart. Frontiers in Physiology. 6: 13. PMID 25688213 DOI: 10.3389/Fphys.2015.00013 |
0.426 |
|
| 2015 |
Carley AN, Taglieri DM, Bi J, Solaro RJ, Lewandowski ED. Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I. Circulation. Heart Failure. 8: 119-27. PMID 25424393 DOI: 10.1161/Circheartfailure.114.001496 |
0.39 |
|
| 2014 |
Ke Y, Wang X, Jin XY, Solaro RJ, Lei M. PAK1 is a novel cardiac protective signaling molecule. Frontiers of Medicine. 8: 399-403. PMID 25416031 DOI: 10.1007/S11684-014-0380-9 |
0.537 |
|
| 2014 |
Cheng Y, Lindert S, Kekenes-Huskey P, Rao VS, Solaro RJ, Rosevear PR, Amaro R, McCulloch AD, McCammon JA, Regnier M. Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophysical Journal. 107: 1675-85. PMID 25296321 DOI: 10.1016/J.Bpj.2014.08.008 |
0.446 |
|
| 2014 |
Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM. Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation. Basic Research in Cardiology. 109: 445. PMID 25280528 DOI: 10.1007/S00395-014-0445-6 |
0.404 |
|
| 2014 |
Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M. Pak1 is required to maintain ventricular Ca²⺠homeostasis and electrophysiological stability through SERCA2a regulation in mice. Circulation. Arrhythmia and Electrophysiology. 7: 938-48. PMID 25217043 DOI: 10.1161/Circep.113.001198 |
0.386 |
|
| 2014 |
Briston SJ, Dibb KM, Solaro RJ, Eisner DA, Trafford AW. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes. Cardiovascular Research. 104: 347-54. PMID 25183792 DOI: 10.1093/Cvr/Cvu201 |
0.443 |
|
| 2014 |
Nagalingam RS, Sundaresan NR, Noor M, Gupta MP, Solaro RJ, Gupta M. Deficiency of cardiomyocyte-specific microRNA-378 contributes to the development of cardiac fibrosis involving a transforming growth factor β (TGFβ1)-dependent paracrine mechanism. The Journal of Biological Chemistry. 289: 27199-214. PMID 25104350 DOI: 10.1074/Jbc.M114.580977 |
0.393 |
|
| 2014 |
Li KL, Rieck D, Solaro RJ, Dong W. In situ time-resolved FRET reveals effects of sarcomere length on cardiac thin-filament activation. Biophysical Journal. 107: 682-93. PMID 25099807 DOI: 10.1016/J.Bpj.2014.05.044 |
0.426 |
|
| 2014 |
Burniston JG, Gramolini AO, Solaro RJ. Cardiac proteomics. Biomed Research International. 2014: 903538. PMID 25025073 DOI: 10.1155/2014/903538 |
0.353 |
|
| 2014 |
Wang R, Wang Y, Lin WK, Zhang Y, Liu W, Huang K, Terrar DA, Solaro RJ, Wang X, Ke Y, Lei M. Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide. Plos One. 9: e101974. PMID 25014109 DOI: 10.1371/Journal.Pone.0101974 |
0.447 |
|
| 2014 |
Koshman YE, Chu M, Kim T, Kalmanson O, Farjah M, Kumar M, Lewis W, Geenen DL, de Tombe P, Goldspink PH, Solaro RJ, Samarel AM. Cardiomyocyte-specific expression of CRNK, the C-terminal domain of PYK2, maintains ventricular function and slows ventricular remodeling in a mouse model of dilated cardiomyopathy. Journal of Molecular and Cellular Cardiology. 72: 281-91. PMID 24713463 DOI: 10.1016/J.Yjmcc.2014.03.021 |
0.426 |
|
| 2014 |
Alegre-Cebollada J, Kosuri P, Giganti D, Eckels E, Rivas-Pardo JA, Hamdani N, Warren CM, Solaro RJ, Linke WA, Fernández JM. S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding. Cell. 156: 1235-46. PMID 24630725 DOI: 10.1016/J.Cell.2014.01.056 |
0.414 |
|
| 2014 |
Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/Circgenetics.113.000324 |
0.474 |
|
| 2014 |
Yar S, Monasky MM, Solaro RJ. Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death. PflüGers Archiv : European Journal of Physiology. 466: 1189-97. PMID 24488009 DOI: 10.1007/S00424-014-1457-7 |
0.514 |
|
| 2014 |
Puglisi JL, Goldspink PH, Gomes AV, Utter MS, Bers DM, Solaro RJ. Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytes. Archives of Biochemistry and Biophysics. 552: 50-9. PMID 24480308 DOI: 10.1016/J.Abb.2014.01.019 |
0.445 |
|
| 2014 |
Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS. PR65A phosphorylation regulates PP2A complex signaling. Plos One. 9: e85000. PMID 24465463 DOI: 10.1371/Journal.Pone.0085000 |
0.468 |
|
| 2014 |
DeSantiago J, Bare DJ, Xiao L, Ke Y, Solaro RJ, Banach K. p21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes. Journal of Molecular and Cellular Cardiology. 67: 77-85. PMID 24380729 DOI: 10.1016/J.Yjmcc.2013.12.017 |
0.428 |
|
| 2014 |
Li K, Rieck DC, Solaro RJ, Dong W. Monitoring Cardiac Troponin Structural Changes using In-Situ Time-Resolved FRET: Implications on the Regulatory Roles of Cross-Bridges and Sarcomere Length Biophysical Journal. 106: 769a-770a. DOI: 10.1016/J.Bpj.2013.11.4227 |
0.439 |
|
| 2014 |
Rieck DC, Zhou Z, Li K, Solaro RJ, Dong W. Truncation of the Mobile Domain of Cardiac Troponin I Results in Biphasic Calcium-Dependent Thin Filament Activation Biophysical Journal. 106: 722a-723a. DOI: 10.1016/J.Bpj.2013.11.3992 |
0.454 |
|
| 2014 |
DeSantiago J, Bare DJ, Ke Y, Solaro RJ, Avitall B, Arora R, Banach K. Increased Risk of Atrial Fibrillation with Attenuated Activity of P21-Activated Kinase Biophysical Journal. 106: 323a. DOI: 10.1016/J.Bpj.2013.11.1860 |
0.4 |
|
| 2013 |
Patel BG, Wilder T, Solaro RJ. Novel control of cardiac myofilament response to calcium by S-glutathionylation at specific sites of myosin binding protein C. Frontiers in Physiology. 4: 336. PMID 24312057 DOI: 10.3389/Fphys.2013.00336 |
0.461 |
|
| 2013 |
Ke Y, Lei M, Wang X, Solaro RJ. Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signaling. Frontiers in Pharmacology. 4: 116. PMID 24098283 DOI: 10.3389/Fphar.2013.00116 |
0.334 |
|
| 2013 |
Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 288: 28925-35. PMID 23960072 DOI: 10.1074/Jbc.M113.466466 |
0.479 |
|
| 2013 |
Rieck DC, Li KL, Ouyang Y, Solaro RJ, Dong WJ. Structural basis for the in situ Ca(2+) sensitization of cardiac troponin C by positive feedback from force-generating myosin cross-bridges. Archives of Biochemistry and Biophysics. 537: 198-209. PMID 23896515 DOI: 10.1016/J.Abb.2013.07.013 |
0.424 |
|
| 2013 |
Monasky MM, Taglieri DM, Henze M, Warren CM, Utter MS, Soergel DG, Violin JD, Solaro RJ. The β-arrestin-biased ligand TRV120023 inhibits angiotensin II-induced cardiac hypertrophy while preserving enhanced myofilament response to calcium. American Journal of Physiology. Heart and Circulatory Physiology. 305: H856-66. PMID 23873795 DOI: 10.1152/Ajpheart.00327.2013 |
0.346 |
|
| 2013 |
Liu W, Zi M, Tsui H, Chowdhury SK, Zeef L, Meng QJ, Travis M, Prehar S, Berry A, Hanley NA, Neyses L, Xiao RP, Oceandy D, Ke Y, Solaro RJ, et al. A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin. Circulation. Heart Failure. 6: 833-44. PMID 23753531 DOI: 10.1161/Circheartfailure.112.000123 |
0.522 |
|
| 2013 |
DeSantiago J, Bare DJ, Ke Y, Sheehan KA, Solaro RJ, Banach K. Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1. Journal of Molecular and Cellular Cardiology. 60: 121-8. PMID 23612118 DOI: 10.1016/J.Yjmcc.2013.04.014 |
0.468 |
|
| 2013 |
Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/Jbc.M113.458695 |
0.474 |
|
| 2013 |
Nagalingam RS, Sundaresan NR, Gupta MP, Geenen DL, Solaro RJ, Gupta M. A cardiac-enriched microRNA, miR-378, blocks cardiac hypertrophy by targeting Ras signaling. The Journal of Biological Chemistry. 288: 11216-32. PMID 23447532 DOI: 10.1074/Jbc.M112.442384 |
0.371 |
|
| 2013 |
Solaro RJ, Henze M, Kobayashi T. Integration of troponin I phosphorylation with cardiac regulatory networks. Circulation Research. 112: 355-66. PMID 23329791 DOI: 10.1161/Circresaha.112.268672 |
0.484 |
|
| 2013 |
Jeong EM, Monasky MM, Gu L, Taglieri DM, Patel BG, Liu H, Wang Q, Greener I, Dudley SC, Solaro RJ. Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties. Journal of Molecular and Cellular Cardiology. 56: 44-54. PMID 23247392 DOI: 10.1016/J.Yjmcc.2012.12.003 |
0.478 |
|
| 2013 |
Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ. Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation. Archives of Biochemistry and Biophysics. 535: 30-8. PMID 23232082 DOI: 10.1016/J.Abb.2012.11.010 |
0.409 |
|
| 2013 |
Monasky MM, Taglieri DM, Jacobson AK, Haizlip KM, Solaro RJ, Janssen PM. Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium. Archives of Biochemistry and Biophysics. 535: 22-9. PMID 23085150 DOI: 10.1016/J.Abb.2012.10.005 |
0.47 |
|
| 2013 |
Henze M, Patrick SE, Hinken A, Scruggs SB, Goldspink P, de Tombe PP, Kobayashi M, Ping P, Kobayashi T, Solaro RJ. New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. Biochimica Et Biophysica Acta. 1833: 823-32. PMID 22940544 DOI: 10.1016/J.Bbamcr.2012.08.012 |
0.522 |
|
| 2013 |
DeSantiago J, Bare D, Ke Y, Solaro RJ, Banach K. P21-Activated Kinase (Pak1) is a Negative Regulator of ROS Generation in Ventricular Myocytes Biophysical Journal. 104: 614a. DOI: 10.1016/J.Bpj.2012.11.3401 |
0.359 |
|
| 2013 |
Yar S, Chowdhury SA, Turner M, Rajan S, Wolska BM, Gaponenko V, Debold EP, Kobayashi T, Wieczorek DF, Solaro RJ. Altered Flexibility affects Regulatory Functions of Cardiac α-Tropomyosin (α-Tm) in a Novel Transgenic Mouse Model Expressing α-Tm-D137L Biophysical Journal. 104: 448a. DOI: 10.1016/J.Bpj.2012.11.2485 |
0.521 |
|
| 2012 |
Ke Y, Lei M, Wang X, Solaro RJ. Novel roles of PAK1 in the heart. Cellular Logistics. 2: 89-94. PMID 23162741 DOI: 10.4161/cl.21497 |
0.41 |
|
| 2012 |
Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/Jbc.M112.402040 |
0.583 |
|
| 2012 |
Lai HL, Grachoff M, McGinley AL, Khan FF, Warren CM, Chowdhury SA, Wolska BM, Solaro RJ, Geenen DL, Wang QT. Maintenance of adult cardiac function requires the chromatin factor Asxl2. Journal of Molecular and Cellular Cardiology. 53: 734-41. PMID 23046516 DOI: 10.1016/J.Yjmcc.2012.08.014 |
0.447 |
|
| 2012 |
Hinken AC, Hanft LM, Scruggs SB, Sadayappan S, Robbins J, Solaro RJ, McDonald KS. Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. Journal of Muscle Research and Cell Motility. 33: 439-48. PMID 22527640 DOI: 10.1007/S10974-012-9294-9 |
0.511 |
|
| 2012 |
Nixon BR, Thawornkaiwong A, Jin J, Brundage EA, Little SC, Davis JP, Solaro RJ, Biesiadecki BJ. AMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function. The Journal of Biological Chemistry. 287: 19136-47. PMID 22493448 DOI: 10.1074/Jbc.M111.323048 |
0.511 |
|
| 2012 |
Knezevic I, Patel A, Sundaresan NR, Gupta MP, Solaro RJ, Nagalingam RS, Gupta M. A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival. The Journal of Biological Chemistry. 287: 12913-26. PMID 22367207 DOI: 10.1074/Jbc.M111.331751 |
0.348 |
|
| 2012 |
Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC. Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity. Circulation Research. 110: 841-50. PMID 22343711 DOI: 10.1161/Circresaha.111.258251 |
0.428 |
|
| 2012 |
Avner BS, Shioura KM, Scruggs SB, Grachoff M, Geenen DL, Helseth DL, Farjah M, Goldspink PH, Solaro RJ. Myocardial infarction in mice alters sarcomeric function via post-translational protein modification. Molecular and Cellular Biochemistry. 363: 203-15. PMID 22160857 DOI: 10.1007/S11010-011-1172-Z |
0.519 |
|
| 2012 |
Monasky MM, Taglieri DM, Patel BG, Chernoff J, Wolska BM, Ke Y, Solaro RJ. p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. 302: H224-30. PMID 22037191 DOI: 10.1152/Ajpheart.00612.2011 |
0.506 |
|
| 2012 |
Jeong E, Monasky MM, Gu L, Taglieri DM, Patel BG, Wang Q, Lardin H, Greener I, Solaro RJ, Dudley SC. Tetrahydrobiopterin Improves Diastolic Heart Failure by Increasing Myofilament Calcium Sensitivity Journal of Cardiac Failure. 18. DOI: 10.1016/J.Cardfail.2012.06.022 |
0.384 |
|
| 2012 |
Ke Y, Taglieri DM, Monasky MM, Solaro RJ. Erratum: Inhibition of angiotensin II-induced ventricular hypertrophy and fibrosis by modulation of Pak1 activity (Biophysical Journal (2012) (556a)) Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2012.02.044 |
0.305 |
|
| 2012 |
Warren CM, Alves MS, Montminy EM, Simon JN, Gaffin RD, Rajan S, Wieczorek DF, Solaro RJ, Wolska BM. Rescue of a Dilated Cardiomyopathy Mouse Model Caused by a Mutation in Tropomyosin (E54K) by Expression of Slow Skeletal Troponin I Biophysical Journal. 102: 560a. DOI: 10.1016/J.Bpj.2011.11.3051 |
0.486 |
|
| 2012 |
Ke Y, Taglieri DM, Michelle MM, Solaro RJ. Inhibition of Angiotensin II-Induced Ventricular Hypertrophy and Fibrosis by Modulation of Pak1 Activity Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3032 |
0.428 |
|
| 2012 |
DeSantiago J, Bare DJ, Sheehan KA, Ke Y, Solaro RJ, Banach K. P21-Activated Kinase (Pak1) is a Direct Modulator of Cardiac Excitation-Contraction Coupling (ECC) Gain Biophysical Journal. 102: 512a. DOI: 10.1016/J.Bpj.2011.11.2802 |
0.433 |
|
| 2012 |
Solaro RJ, Leinwand LA. Role of sarcomeres in cellular tension, shortening, and signaling in cardiac muscle Muscle. 1: 161-172. DOI: 10.1016/B978-0-12-381510-1.00013-2 |
0.515 |
|
| 2011 |
Liu W, Zi M, Naumann R, Ulm S, Jin J, Taglieri DM, Prehar S, Gui J, Tsui H, Xiao RP, Neyses L, Solaro RJ, Ke Y, Cartwright EJ, Lei M, et al. Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart. Circulation. 124: 2702-15. PMID 22082674 DOI: 10.1161/Circulationaha.111.048785 |
0.482 |
|
| 2011 |
Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, Wang X, Chernoff J, Wolska BM, Ke Y, Solaro RJ. Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A. Journal of Molecular and Cellular Cardiology. 51: 988-96. PMID 21971074 DOI: 10.1016/J.Yjmcc.2011.09.016 |
0.484 |
|
| 2011 |
Belin RJ, Sumandea MP, Sievert GA, Harvey LA, Geenen DL, Solaro RJ, de Tombe PP. Interventricular differences in myofilament function in experimental congestive heart failure. PflüGers Archiv : European Journal of Physiology. 462: 795-809. PMID 21927813 DOI: 10.1007/S00424-011-1024-4 |
0.533 |
|
| 2011 |
Ai X, Jiang A, Ke Y, Solaro RJ, Pogwizd SM. Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovascular Research. 92: 106-14. PMID 21727092 DOI: 10.1093/Cvr/Cvr163 |
0.457 |
|
| 2011 |
Egom EE, Mohamed TM, Mamas MA, Shi Y, Liu W, Chirico D, Stringer SE, Ke Y, Shaheen M, Wang T, Chacko S, Wang X, Solaro RJ, Fath-Ordoubadi F, Cartwright EJ, et al. Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1487-95. PMID 21705677 DOI: 10.1152/Ajpheart.01003.2010 |
0.44 |
|
| 2011 |
Pound KM, Arteaga GM, Fasano M, Wilder T, Fischer SK, Warren CM, Wende AR, Farjah M, Abel ED, Solaro RJ, Lewandowski ED. Expression of slow skeletal TnI in adult mouse hearts confers metabolic protection to ischemia. Journal of Molecular and Cellular Cardiology. 51: 236-43. PMID 21640727 DOI: 10.1016/J.Yjmcc.2011.05.014 |
0.437 |
|
| 2011 |
Scruggs SB, Solaro RJ. The significance of regulatory light chain phosphorylation in cardiac physiology. Archives of Biochemistry and Biophysics. 510: 129-34. PMID 21345328 DOI: 10.1016/J.Abb.2011.02.013 |
0.491 |
|
| 2011 |
Solaro RJ, Kobayashi T. Protein phosphorylation and signal transduction in cardiac thin filaments. The Journal of Biological Chemistry. 286: 9935-40. PMID 21257760 DOI: 10.1074/Jbc.R110.197731 |
0.509 |
|
| 2011 |
Solaro RJ, Stull JT. Thematic minireview series on signaling in cardiac sarcomeres in health and disease. The Journal of Biological Chemistry. 286: 9895. PMID 21257756 DOI: 10.1074/Jbc.R110.214403 |
0.448 |
|
| 2011 |
Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/S10974-010-9237-2 |
0.826 |
|
| 2011 |
Shioura KM, Farjah M, Geenen DL, Solaro RJ, Goldspink PH. Myofilament calcium sensitization delays decompensated hypertrophy differently between the sexes following myocardial infarction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 300: R361-8. PMID 21106909 DOI: 10.1152/Ajpregu.00321.2010 |
0.447 |
|
| 2011 |
Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/J.Yjmcc.2010.10.032 |
0.45 |
|
| 2011 |
Sheehan KA, Ke Y, Banach K, Solaro RJ. P21-Activated Kinase-1 and Fty720 Alter Atrial Excitation-Contraction Coupling Biophysical Journal. 100: 80a. DOI: 10.1016/J.Bpj.2010.12.644 |
0.445 |
|
| 2011 |
Taglieri DM, Knezevic II, Chernoff J, Solaro RJ, Ke Y. Erk1-Mediated Development of Left Ventricular Cardiac Hypertrophy in a P21 Activated Kinase-1 (Pak1) Knockout Mouse Model Biophysical Journal. 100: 289a. DOI: 10.1016/J.Bpj.2010.12.1783 |
0.41 |
|
| 2011 |
Solaro RJ. Modulation of Cardiac Myofilament Activity by Protein Phosphorylation Comprehensive Physiology. DOI: 10.1002/Cphy.Cp020107 |
0.466 |
|
| 2010 |
Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/J.Yjmcc.2010.09.010 |
0.471 |
|
| 2010 |
Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/Circulationaha.110.950089 |
0.425 |
|
| 2010 |
Jagatheesan G, Rajan S, Ahmed RP, Petrashevskaya N, Boivin G, Arteaga GM, Tae HJ, Liggett SB, Solaro RJ, Wieczorek DF. Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity. Journal of Muscle Research and Cell Motility. 31: 227-39. PMID 20803058 DOI: 10.1007/S10974-010-9228-3 |
0.456 |
|
| 2010 |
Solaro RJ, Sheehan KA, Lei M, Ke Y. The curious role of sarcomeric proteins in control of diverse processes in cardiac myocytes. The Journal of General Physiology. 136: 13-9. PMID 20584888 DOI: 10.1085/Jgp.201010462 |
0.433 |
|
| 2010 |
Avner BS, Hinken AC, Yuan C, Solaro RJ. H2O2 alters rat cardiac sarcomere function and protein phosphorylation through redox signaling. American Journal of Physiology. Heart and Circulatory Physiology. 299: H723-30. PMID 20562337 DOI: 10.1152/Ajpheart.00050.2010 |
0.441 |
|
| 2010 |
Solaro RJ, Warren CM, Scruggs SB. Why is it important to analyze the cardiac sarcomere subproteome? Expert Review of Proteomics. 7: 311-4. PMID 20536300 DOI: 10.1586/epr.10.15 |
0.351 |
|
| 2010 |
Solaro RJ. Sarcomere control mechanisms and the dynamics of the cardiac cycle. Journal of Biomedicine & Biotechnology. 2010: 105648. PMID 20467475 DOI: 10.1155/2010/105648 |
0.459 |
|
| 2010 |
Scruggs SB, Reisdorph R, Armstrong ML, Warren CM, Reisdorph N, Solaro RJ, Buttrick PM. A novel, in-solution separation of endogenous cardiac sarcomeric proteins and identification of distinct charged variants of regulatory light chain. Molecular & Cellular Proteomics : McP. 9: 1804-18. PMID 20445002 DOI: 10.1074/Mcp.M110.000075 |
0.439 |
|
| 2010 |
Biesiadecki BJ, Tachampa K, Yuan C, Jin JP, de Tombe PP, Solaro RJ. Removal of the cardiac troponin I N-terminal extension improves cardiac function in aged mice. The Journal of Biological Chemistry. 285: 19688-98. PMID 20410305 DOI: 10.1074/Jbc.M109.086892 |
0.525 |
|
| 2010 |
Warren CM, Geenen DL, Helseth DL, Xu H, Solaro RJ. Sub-proteomic fractionation, iTRAQ, and OFFGEL-LC-MS/MS approaches to cardiac proteomics. Journal of Proteomics. 73: 1551-61. PMID 20394843 DOI: 10.1016/J.Jprot.2010.03.016 |
0.37 |
|
| 2010 |
Solaro RJ, van der Velden J. Why does troponin I have so many phosphorylation sites? Fact and fancy. Journal of Molecular and Cellular Cardiology. 48: 810-6. PMID 20188739 DOI: 10.1016/J.Yjmcc.2010.02.014 |
0.521 |
|
| 2010 |
Lu QW, Hinken AC, Patrick SE, Solaro RJ, Kobayashi T. Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments. The Journal of Biological Chemistry. 285: 11810-7. PMID 20164197 DOI: 10.1074/Jbc.M109.055657 |
0.533 |
|
| 2010 |
Ke Y, Sheehan KA, Egom EE, Lei M, Solaro RJ. Novel bradykinin signaling in adult rat cardiac myocytes through activation of p21-activated kinase. American Journal of Physiology. Heart and Circulatory Physiology. 298: H1283-9. PMID 20154261 DOI: 10.1152/Ajpheart.01070.2009 |
0.508 |
|
| 2010 |
Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E, Kass DA. PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation. Basic Research in Cardiology. 105: 337-47. PMID 20107996 DOI: 10.1007/S00395-010-0084-5 |
0.41 |
|
| 2010 |
Egom EE, Ke Y, Solaro RJ, Lei M. Cardioprotection in ischemia/reperfusion injury: spotlight on sphingosine-1-phosphate and bradykinin signalling. Progress in Biophysics and Molecular Biology. 103: 142-7. PMID 20080123 DOI: 10.1016/J.Pbiomolbio.2010.01.001 |
0.374 |
|
| 2010 |
Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... ... Solaro RJ, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/Circulationaha.109.889725 |
0.814 |
|
| 2010 |
Egom EE, Ke Y, Musa H, Mohamed TM, Wang T, Cartwright E, Solaro RJ, Lei M. FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling. Journal of Molecular and Cellular Cardiology. 48: 406-14. PMID 19852968 DOI: 10.1016/J.Yjmcc.2009.10.009 |
0.348 |
|
| 2010 |
Warren CM, Geenen DL, Helseth DL, Solaro RJ. Sub-Proteomic Fractionation of Rat Cardiac Tissue: Comparing Ischemic Vs Normal Remote Region with In-Solution Based Proteomics Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3942 |
0.364 |
|
| 2010 |
Avner BS, Shioura KM, Scruggs SB, Helseth DL, Goldspink PH, Solaro RJ. Alterations to Cardiac Muscle Function and Sarcomeric Proteins Following Myocardial Infarction Biophysical Journal. 98: 543a-544a. DOI: 10.1016/J.Bpj.2009.12.2948 |
0.507 |
|
| 2010 |
Karam C, Alves M, Wolsa BM, Rajan S, Wieczorek DF, Solaro RJ. Tropomyosin-Kappa Alters Cardiac Dynamics in a Mouse Heart Model Biophysical Journal. 98: 358a-359a. DOI: 10.1016/J.Bpj.2009.12.1935 |
0.83 |
|
| 2010 |
Biesiadecki BJ, Alves ML, Jagatheesan G, Liu B, Scellini B, Tesi C, Davis JP, Poggesi C, Wieczorek DF, Wolska BM, Solaro RJ. Tropomyosin Pseudo-Phosphorylation and Muscle Kinetics Biophysical Journal. 98: 350a. DOI: 10.1016/J.Bpj.2009.12.1893 |
0.506 |
|
| 2009 |
Kirk JA, MacGowan GA, Evans C, Smith SH, Warren CM, Mamidi R, Chandra M, Stewart AF, Solaro RJ, Shroff SG. Left ventricular and myocardial function in mice expressing constitutively pseudophosphorylated cardiac troponin I. Circulation Research. 105: 1232-9. PMID 19850940 DOI: 10.1161/Circresaha.109.205427 |
0.532 |
|
| 2009 |
Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/Ajpheart.00329.2008 |
0.465 |
|
| 2009 |
Engel PL, Hinken A, Solaro RJ. Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments. Journal of Molecular and Cellular Cardiology. 47: 359-64. PMID 19426736 DOI: 10.1016/J.Yjmcc.2009.04.016 |
0.466 |
|
| 2009 |
Solaro RJ. CK-1827452, a sarcomere-directed cardiac myosin activator for acute and chronic heart disease. Idrugs : the Investigational Drugs Journal. 12: 243-51. PMID 19350469 |
0.452 |
|
| 2009 |
Warren CM, Kobayashi T, Solaro RJ. Sites of intra- and intermolecular cross-linking of the N-terminal extension of troponin I in human cardiac whole troponin complex. The Journal of Biological Chemistry. 284: 14258-66. PMID 19321456 DOI: 10.1074/Jbc.M807621200 |
0.39 |
|
| 2009 |
Hartman TJ, Martin JL, Solaro RJ, Samarel AM, Russell B. CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms. American Journal of Physiology. Cell Physiology. 296: C1034-9. PMID 19295171 DOI: 10.1152/Ajpcell.00544.2008 |
0.39 |
|
| 2009 |
Solaro RJ. Maintaining cooperation among cardiac myofilament proteins through thick and thin. The Journal of Physiology. 587: 3. PMID 19119179 DOI: 10.1113/Jphysiol.2008.166751 |
0.471 |
|
| 2009 |
Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation. The Journal of Biological Chemistry. 284: 5097-106. PMID 19106098 DOI: 10.1074/Jbc.M807414200 |
0.513 |
|
| 2009 |
Sheehan KA, Ke Y, Wolska BM, Solaro RJ. Expression of active p21-activated kinase-1 induces Ca2+ flux modification with altered regulatory protein phosphorylation in cardiac myocytes. American Journal of Physiology. Cell Physiology. 296: C47-58. PMID 18923061 DOI: 10.1152/Ajpcell.00012.2008 |
0.44 |
|
| 2009 |
Jagatheesan G, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Liggett SB, Solaro RJ, Wieczorek DF. An Internal Domain of Beta Tropomyosin Increases Myofilament Calcium Sensitivity Biophysical Journal. 96: 504a. DOI: 10.1016/J.Bpj.2008.12.2597 |
0.404 |
|
| 2009 |
Scruggs SB, Reisdorph R, Buttrick PM, Reisdorph N, Solaro RJ. In-Solution Proteomic Workflow for Purification of Endogenous Sarcomeric Proteins and Identification of Distinct Charged Variants of Regulatory Light Chain Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2591 |
0.403 |
|
| 2009 |
Wilder T, Hinken AC, Solaro RJ. Altered Myofilament Targeting with Differential PKCδ Activation Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2582 |
0.439 |
|
| 2009 |
Avner BS, Solaro RJ. Reactive Oxygen Species Alter Activation Of Cardiac Myofilaments And Modify Sarcomeric Proteins Biophysical Journal. 96: 497a. DOI: 10.1016/J.Bpj.2008.12.2565 |
0.47 |
|
| 2009 |
Biesiadecki BJ, Thawornkaiwong A, Jin J, Solaro R. Troponin I Ser-150 pseudo-phosphorylation alters cardiac contractile mechanics Biophysical Journal. 96: 227a. DOI: 10.1016/J.Bpj.2008.12.1115 |
0.431 |
|
| 2009 |
Warren CM, Kobayashi T, Solaro RJ. Human Cardiac Troponin Cross-Linking and the Functional Consequences Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1114 |
0.342 |
|
| 2008 |
Yuan C, Solaro RJ. Myofilament proteins: From cardiac disorders to proteomic changes. Proteomics. Clinical Applications. 2: 788-99. PMID 21136879 DOI: 10.1002/Prca.200780076 |
0.491 |
|
| 2008 |
Ke Y, Solaro RJ. Use of a decoy peptide to purify p21 activated kinase-1 in cardiac muscle and identification of ceramide-related activation. Biologics : Targets & Therapy. 2: 903-9. PMID 19707468 DOI: 10.2147/Btt.S3870 |
0.457 |
|
| 2008 |
Ke Y, Lei M, Solaro RJ. Regulation of cardiac excitation and contraction by p21 activated kinase-1. Progress in Biophysics and Molecular Biology. 98: 238-50. PMID 19351515 DOI: 10.1016/J.Pbiomolbio.2009.01.007 |
0.388 |
|
| 2008 |
Baudenbacher F, Schober T, Pinto JR, Sidorov VY, Hilliard F, Solaro RJ, Potter JD, Knollmann BC. Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice. The Journal of Clinical Investigation. 118: 3893-903. PMID 19033660 DOI: 10.1172/Jci36642 |
0.489 |
|
| 2008 |
Rudy Y, Ackerman MJ, Bers DM, Clancy CE, Houser SR, London B, McCulloch AD, Przywara DA, Rasmusson RL, Solaro RJ, Trayanova NA, Van Wagoner DR, Varró A, Weiss JN, Lathrop DA. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 118: 1202-11. PMID 18779456 DOI: 10.1161/Circulationaha.108.772715 |
0.418 |
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| 2008 |
Solaro RJ. Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins. The Journal of Biological Chemistry. 283: 26829-33. PMID 18567577 DOI: 10.1074/Jbc.R800037200 |
0.523 |
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| 2008 |
Yuan C, Sheng Q, Tang H, Li Y, Zeng R, Solaro RJ. Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 295: H647-56. PMID 18552161 DOI: 10.1152/Ajpheart.00357.2008 |
0.475 |
|
| 2008 |
Sumandea MP, Rybin VO, Hinken AC, Wang C, Kobayashi T, Harleton E, Sievert G, Balke CW, Feinmark SJ, Solaro RJ, Steinberg SF. Tyrosine phosphorylation modifies protein kinase C δ-dependent phosphorylation of cardiac troponin I Journal of Biological Chemistry. 283: 22680-22689. PMID 18550549 DOI: 10.1074/Jbc.M802396200 |
0.435 |
|
| 2008 |
Minami H, Wolska BM, Stojanovic MO, Solaro RJ. Reversal of effects of acidosis on contraction of rat heart myocytes by CGP-48506. Frontiers in Bioscience : a Journal and Virtual Library. 13: 5638-45. PMID 18508612 DOI: 10.2741/3106 |
0.349 |
|
| 2008 |
Tachampa K, Kobayashi T, Wang H, Martin AF, Biesiadecki BJ, Solaro RJ, de Tombe PP. Increased cross-bridge cycling kinetics after exchange of C-terminal truncated troponin I in skinned rat cardiac muscle. The Journal of Biological Chemistry. 283: 15114-21. PMID 18378675 DOI: 10.1074/Jbc.M801636200 |
0.507 |
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| 2008 |
Solaro RJ, de Tombe PP. Review focus series: sarcomeric proteins as key elements in integrated control of cardiac function. Cardiovascular Research. 77: 616-8. PMID 18192242 DOI: 10.1093/Cvr/Cvn004 |
0.499 |
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| 2008 |
Solaro RJ, Rosevear P, Kobayashi T. The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation. Biochemical and Biophysical Research Communications. 369: 82-7. PMID 18162178 DOI: 10.1016/J.Bbrc.2007.12.114 |
0.509 |
|
| 2008 |
Warren CM, Arteaga GM, Rajan S, Ahmed RP, Wieczorek DF, Solaro RJ. Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy. Proteomics. 8: 100-5. PMID 18095372 DOI: 10.1002/Pmic.200700772 |
0.412 |
|
| 2008 |
Urboniene QZD, Ornatowska M, Solaro RJ, Christman JW, Xiao L. Cardiac-Specific Overexpression of a Dominant Negative (DN) p67phox Mutant Shows Reduction in Mouse Heart Size Journal of Cardiac Failure. 14. DOI: 10.1016/J.Cardfail.2008.06.012 |
0.476 |
|
| 2007 |
Nowak G, Peña JR, Urboniene D, Geenen DL, Solaro RJ, Wolska BM. Correlations between alterations in length-dependent Ca2+ activation of cardiac myofilaments and the end-systolic pressure-volume relation. Journal of Muscle Research and Cell Motility. 28: 415-9. PMID 18365757 DOI: 10.1007/S10974-008-9136-Y |
0.526 |
|
| 2007 |
Howarth JW, Meller J, Solaro RJ, Trewhella J, Rosevear PR. Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin. Journal of Molecular Biology. 373: 706-22. PMID 17854829 DOI: 10.1016/J.Jmb.2007.08.035 |
0.433 |
|
| 2007 |
Solaro RJ. Mechanisms of the Frank-Starling law of the heart: the beat goes on. Biophysical Journal. 93: 4095-6. PMID 17766360 DOI: 10.1529/Biophysj.107.117200 |
0.551 |
|
| 2007 |
Wu SC, Solaro RJ. Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins. The Journal of Biological Chemistry. 282: 30691-8. PMID 17724026 DOI: 10.1074/Jbc.M703670200 |
0.431 |
|
| 2007 |
Solaro RJ. Translational medicine with a capital T, troponin T, that is Circulation Research. 101: 114-115. PMID 17641232 DOI: 10.1161/Circresaha.107.157420 |
0.441 |
|
| 2007 |
Sheehan KA, Ke Y, Solaro RJ. p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 293. PMID 17609315 DOI: 10.1152/Ajpregu.00253.2007 |
0.528 |
|
| 2007 |
Belin RJ, Sumandea MP, Allen EJ, Schoenfelt K, Wang H, Solaro RJ, de Tombe PP. Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure. Circulation Research. 101: 195-204. PMID 17556659 DOI: 10.1161/Circresaha.107.148288 |
0.478 |
|
| 2007 |
Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity. Circulation Research. 101: 205-14. PMID 17556658 DOI: 10.1161/Circresaha.107.148379 |
0.543 |
|
| 2007 |
Xiao L, Zhao Q, Du Y, Yuan C, Solaro RJ, Buttrick PM. PKCepsilon increases phosphorylation of the cardiac myosin binding protein C at serine 302 both in vitro and in vivo. Biochemistry. 46: 7054-61. PMID 17503784 DOI: 10.1021/Bi700467K |
0.45 |
|
| 2007 |
Biesiadecki BJ, Kobayashi T, Walker JS, Solaro RJ, de Tombe PP. The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation. Circulation Research. 100: 1486-93. PMID 17446435 DOI: 10.1161/01.Res.0000267744.92677.7F |
0.535 |
|
| 2007 |
Hinken AC, Solaro RJ. A dominant role of cardiac molecular motors in the intrinsic regulation of ventricular ejection and relaxation. Physiology (Bethesda, Md.). 22: 73-80. PMID 17420299 DOI: 10.1152/Physiol.00043.2006 |
0.362 |
|
| 2007 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. American Journal of Physiology. Heart and Circulatory Physiology. 293: H949-58. PMID 17416600 DOI: 10.1152/Ajpheart.01341.2006 |
0.431 |
|
| 2007 |
Ke Y, Lei M, Collins TP, Rakovic S, Mattick PA, Yamasaki M, Brodie MS, Terrar DA, Solaro RJ. Regulation of L-type calcium channel and delayed rectifier potassium channel activity by p21-activated kinase-1 in guinea pig sinoatrial node pacemaker cells. Circulation Research. 100: 1317-27. PMID 17413045 DOI: 10.1161/01.Res.0000266742.51389.A4 |
0.394 |
|
| 2007 |
Solaro RJ. Nitroxyl effects on myocardium provide new insights into the significance of altered myofilament response to calcium in the regulation of contractility Journal of Physiology. 580: 697. PMID 17347260 DOI: 10.1113/Jphysiol.2007.131649 |
0.476 |
|
| 2007 |
Davis JP, Norman C, Kobayashi T, Solaro RJ, Swartz DR, Tikunova SB. Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C. Biophysical Journal. 92: 3195-206. PMID 17293397 DOI: 10.1529/Biophysj.106.095406 |
0.491 |
|
| 2007 |
Solaro RJ, Arteaga GM. Heart failure, ischemia/reperfusion injury and cardiac troponin. Advances in Experimental Medicine and Biology. 592: 191-200. PMID 17278366 DOI: 10.1007/978-4-431-38453-3_17 |
0.494 |
|
| 2007 |
Vahebi S, Ota A, Li M, Warren CM, de Tombe PP, Wang Y, Solaro RJ. p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. Circulation Research. 100: 408-15. PMID 17234967 DOI: 10.1161/01.Res.0000258116.60404.Ad |
0.473 |
|
| 2006 |
Engel PL, Kobayashi T, Biesiadecki B, Davis J, Tikunova S, Wu S, Solaro RJ. Identification of a region of troponin I important in signaling cross-bridge-dependent activation of cardiac myofilaments. The Journal of Biological Chemistry. 282: 183-93. PMID 17099250 DOI: 10.1074/Jbc.M512337200 |
0.397 |
|
| 2006 |
Pyle WG, La Rotta G, de Tombe PP, Sumandea MP, Solaro RJ. Control of cardiac myofilament activation and PKC-betaII signaling through the actin capping protein, CapZ. Journal of Molecular and Cellular Cardiology. 41: 537-43. PMID 16870209 DOI: 10.1016/J.Yjmcc.2006.06.006 |
0.465 |
|
| 2006 |
McCall SJ, Nassar R, Malouf NN, Saunders AJ, Oakeley AE, Henderson PM, Solaro RJ, Pielak GJ, Alexander KA, Anderson PA. Development and cardiac contractility: cardiac troponin T isoforms and cytosolic calcium in rabbit. Pediatric Research. 60: 276-81. PMID 16857772 DOI: 10.1203/01.Pdr.0000233004.95404.1F |
0.433 |
|
| 2006 |
Belin RJ, Sumandea MP, Kobayashi T, Walker LA, Rundell VL, Urboniene D, Yuzhakova M, Ruch SH, Geenen DL, Solaro RJ, de Tombe PP. Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2344-53. PMID 16815982 DOI: 10.1152/Ajpheart.00541.2006 |
0.511 |
|
| 2006 |
Biesiadecki BJ, Solaro RJ. When hearts fail so does skeletal muscle: breaking a vicious cycle. Circulation Research. 98: 1456-8. PMID 16794192 DOI: 10.1161/01.Res.0000231259.29646.74 |
0.462 |
|
| 2006 |
Kobayashi T, Solaro RJ. Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I Journal of Biological Chemistry. 281: 13471-13477. PMID 16531415 DOI: 10.1074/Jbc.M509561200 |
0.437 |
|
| 2006 |
Scruggs SB, Walker LA, Lyu T, Geenen DL, Solaro RJ, Buttrick PM, Goldspink PH. Partial replacement of cardiac troponin i with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCε phosphorylation Journal of Molecular and Cellular Cardiology. 40: 465-473. PMID 16445938 DOI: 10.1016/J.Yjmcc.2005.12.009 |
0.508 |
|
| 2006 |
Kass DA, Solaro RJ. Mechanisms and use of calcium-sensitizing agents in the failing heart Circulation. 113: 305-315. PMID 16418450 DOI: 10.1161/Circulationaha.105.542407 |
0.515 |
|
| 2006 |
Solaro RJ. Novel Roles of Cardiac Sarcomeric Proteins in Signaling and Signal Transduction Journal of Molecular and Cellular Cardiology. 40: 994. DOI: 10.1016/J.Yjmcc.2006.03.218 |
0.378 |
|
| 2006 |
Zhao Q, Xiao L, Du Y, Yuan C, Solaro RJ, Goldspink PH, Buttrick PM. Serine (Ser) 302 of Cardiac Myosin Binding Protein C (cMyBPC) Is a Unique PKCɛ Phosphorylation Site Both In Vivo and In Vitro Journal of Cardiac Failure. 12. DOI: 10.1016/J.Cardfail.2006.06.149 |
0.44 |
|
| 2005 |
Solaro RJ. Remote control of A-band cardiac thin filaments by the I-Z-I protein network of cardiac sarcomeres Trends in Cardiovascular Medicine. 15: 148-152. PMID 16099379 DOI: 10.1016/J.Tcm.2005.04.007 |
0.484 |
|
| 2005 |
Arteaga GM, Warren CM, Milutinovic S, Martin AF, Solaro RJ. Specific enhancement of sarcomeric response to Ca2+ protects murine myocardium against ischemia-reperfusion dysfunction American Journal of Physiology - Heart and Circulatory Physiology. 289. PMID 16024565 DOI: 10.1152/Ajpheart.00520.2005 |
0.519 |
|
| 2005 |
Urboniene D, Dias FAL, Peña JR, Walker LA, Solaro RJ, Wolska BM. Expression of Slow Skeletal Troponin I in Adult Mouse Heart Helps to Maintain the Left Ventricular Systolic Function During Respiratory Hypercapnia Circulation Research. 97: 70-77. PMID 15961720 DOI: 10.1161/01.Res.0000173849.68636.1E |
0.438 |
|
| 2005 |
Layland J, Cave AC, Warren C, Grieve DJ, Sparks E, Kentish JC, Solaro RJ, Shah AM. Protection against endotoxemia-induced contractile dysfunction in mice with cardiac-specific expression of slow skeletal troponin I. The Faseb Journal. 19: 1137-1139. PMID 15855227 DOI: 10.1096/Fj.04-2519Fje |
0.514 |
|
| 2005 |
Vahebi S, Kobayashi T, Warren CM, de Tombe PP, Solaro RJ. Functional effects of rho-kinase-dependent phosphorylation of specific sites on cardiac troponin. Circulation Research. 96: 740-7. PMID 15774859 DOI: 10.1161/01.Res.0000162457.56568.7D |
0.474 |
|
| 2005 |
Layland J, Solaro RJ, Shah AM. Regulation of cardiac contractile function by troponin I phosphorylation Cardiovascular Research. 66: 12-21. PMID 15769444 DOI: 10.1016/J.Cardiores.2004.12.022 |
0.539 |
|
| 2005 |
Kobayashi T, Solaro RJ. Calcium, thin filaments, and the integrative biology of cardiac contractility Annual Review of Physiology. 67: 39-67. PMID 15709952 DOI: 10.1146/annurev.physiol.67.040403.114025 |
0.426 |
|
| 2005 |
Kobayashi T, Yang X, Walker LA, Van Breemen RB, Solaro RJ. A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: Identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C Journal of Molecular and Cellular Cardiology. 38: 213-218. PMID 15623438 DOI: 10.1016/J.Yjmcc.2004.10.014 |
0.405 |
|
| 2004 |
Parmacek MS, Solaro RJ. Biology of the troponin complex in cardiac myocytes. Progress in Cardiovascular Diseases. 47: 159-76. PMID 15736582 DOI: 10.1016/J.Pcad.2004.07.003 |
0.563 |
|
| 2004 |
Sorsa T, Pollesello P, Solaro RJ. The contractile apparatus as a target for drugs against heart failure: Interaction of levosimendan, a calcium sensitiser, with cardiac troponin c Molecular and Cellular Biochemistry. 266: 87-107. PMID 15646030 DOI: 10.1023/B:Mcbi.0000049141.37823.19 |
0.421 |
|
| 2004 |
Gomes AV, Venkatraman G, Davis JP, Tikunova SB, Engel P, Solaro RJ, Potter JD. Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart. The Journal of Biological Chemistry. 279: 49579-87. PMID 15358779 DOI: 10.1074/Jbc.M407340200 |
0.472 |
|
| 2004 |
Goldspink PH, Montgomery DE, Walker LA, Urboniene D, McKinney RD, Geenen DL, Solaro RJ, Buttrick PM. Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure. Circulation Research. 95: 424-32. PMID 15242976 DOI: 10.1161/01.Res.0000138299.85648.92 |
0.547 |
|
| 2004 |
Sumandea MP, Burkart EM, Kobayashi T, De Tombe PP, Solaro RJ. Molecular and integrated biology of thin filament protein phosphorylation in heart muscle. Annals of the New York Academy of Sciences. 1015: 39-52. PMID 15201148 DOI: 10.1196/Annals.1302.004 |
0.478 |
|
| 2004 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga G, de Tombe PP, Solaro RJ, Wieczorek DF. Physiological significance of troponin T binding domains in striated muscle tropomyosin. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1484-94. PMID 15191887 DOI: 10.1152/Ajpheart.01112.2003 |
0.489 |
|
| 2004 |
Kobayashi T, Dong WJ, Burkart EM, Cheung HC, Solaro RJ. Effects of protein kinase C dependent phosphorylation and a familial hypertrophic cardiomyopathy-related mutation of cardiac troponin I on structural transition of troponin C and myofilament activation. Biochemistry. 43: 5996-6004. PMID 15147183 DOI: 10.1021/Bi036073N |
0.422 |
|
| 2004 |
Solaro RJ. The special structure and function of troponin I in regulation of cardiac contraction and relaxation Advances in Experimental Medicine and Biology. 538: 389-402. PMID 15098685 DOI: 10.1007/978-1-4419-9029-7_36 |
0.495 |
|
| 2004 |
Pyle WG, Solaro RJ. At the Crossroads of Myocardial Signaling: The Role of Z-Discs in Intracellular Signaling and Cardiac Function Circulation Research. 94: 296-305. PMID 14976140 DOI: 10.1161/01.Res.0000116143.74830.A9 |
0.455 |
|
| 2004 |
Layland J, Grieve DJ, Cave AC, Sparks E, Solaro RJ, Shah AM. Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically. The Journal of Physiology. 556: 835-847. PMID 14966306 DOI: 10.1113/Jphysiol.2004.061176 |
0.49 |
|
| 2004 |
Roman BB, Goldspink PH, Spaite E, Urboniene D, McKinney R, Geenen DL, Solaro RJ, Buttrick PM. Inhibition of PKC phosphorylation of cTnI improves cardiac performance in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 286: H2089-95. PMID 14726296 DOI: 10.1152/Ajpheart.00582.2003 |
0.482 |
|
| 2004 |
Ke Y, Wang L, Pyle WG, de Tombe PP, Solaro RJ. Intracellular localization and functional effects of P21-activated kinase-1 (Pak1) in cardiac myocytes. Circulation Research. 94: 194-200. PMID 14670848 DOI: 10.1161/01.Res.0000111522.02730.56 |
0.521 |
|
| 2003 |
Burkart EM, Arteaga GM, Sumandea MP, Prabhakar R, Wieczorek DF, Solaro RJ. Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 35: 1285-93. PMID 14519438 DOI: 10.1016/S0022-2828(03)00240-2 |
0.519 |
|
| 2003 |
Sumandea MP, Pyle WG, Kobayashi T, de Tombe PP, Solaro RJ. Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T. The Journal of Biological Chemistry. 278: 35135-44. PMID 12832403 DOI: 10.1074/Jbc.M306325200 |
0.463 |
|
| 2003 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Vahebi S, DeTombe P, Solaro RJ, Labitzke E, Hilliard G, Wieczorek DF. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin. The Journal of Biological Chemistry. 278: 23204-11. PMID 12690096 DOI: 10.1074/Jbc.M303073200 |
0.423 |
|
| 2003 |
Konhilas JP, Irving TC, Wolska BM, Jweied EE, Martin AF, Solaro RJ, de Tombe PP. Troponin I in the murine myocardium: influence on length-dependent activation and interfilament spacing. The Journal of Physiology. 547: 951-61. PMID 12562915 DOI: 10.1113/Jphysiol.2002.038117 |
0.514 |
|
| 2003 |
Burkart EM, Sumandea MP, Kobayashi T, Nili M, Martin AF, Homsher E, Solaro RJ. Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity. The Journal of Biological Chemistry. 278: 11265-72. PMID 12551921 DOI: 10.1074/jbc.M210712200 |
0.411 |
|
| 2002 |
Solaro RJ, Varghese J, Marian AJ, Chandra M. Molecular mechanisms of cardiac myofilament activation: modulation by pH and a troponin T mutant R92Q. Basic Research in Cardiology. 97: I102-10. PMID 12479243 DOI: 10.1007/S003950200038 |
0.402 |
|
| 2002 |
Arteaga GM, Kobayashi T, Solaro RJ. Molecular actions of drugs that sensitize cardiac myofilaments to Ca2+ Annals of Medicine. 34: 248-258. PMID 12371709 DOI: 10.1080/078538902320322510 |
0.472 |
|
| 2002 |
Solaro RJ, Montgomery DM, Wang L, Burkart EM, Ke Y, Vahebi S, Buttrick P. Integration of pathways that signal cardiac growth with modulation of myofilament activity. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 9: 523-33. PMID 12360133 DOI: 10.1067/Mnc.2002.127626 |
0.414 |
|
| 2002 |
Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1344-53. PMID 12234784 DOI: 10.1152/Ajpheart.00351.2002 |
0.501 |
|
| 2002 |
Pyle WG, Sumandea MP, Solaro RJ, De Tombe PP. Troponin I serines 43/45 and regulation of cardiac myofilament function. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1215-24. PMID 12181153 DOI: 10.1152/Ajpheart.00128.2002 |
0.488 |
|
| 2002 |
Martin AF, Phillips RM, Kumar A, Crawford K, Abbas Z, Lessard JL, de Tombe P, Solaro RJ. Ca(2+) activation and tension cost in myofilaments from mouse hearts ectopically expressing enteric gamma-actin. American Journal of Physiology. Heart and Circulatory Physiology. 283: H642-9. PMID 12124211 DOI: 10.1152/Ajpheart.00890.2001 |
0.509 |
|
| 2002 |
Solaro RJ, Burkart EM. Functional Defects in Troponin and the Systems Biology of Heart Failure Journal of Molecular and Cellular Cardiology. 34: 689-693. PMID 12099706 DOI: 10.1006/Jmcc.2002.2028 |
0.36 |
|
| 2002 |
Pyle WG, Hart MC, Cooper JA, Sumandea MP, de Tombe PP, Solaro RJ. Actin capping protein: an essential element in protein kinase signaling to the myofilaments. Circulation Research. 90: 1299-306. PMID 12089068 DOI: 10.1161/01.Res.0000024389.03152.22 |
0.519 |
|
| 2002 |
Montgomery DE, Wolska BM, Pyle WG, Roman BB, Dowell JC, Buttrick PM, Koretsky AP, Del Nido P, Solaro RJ. alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2397-405. PMID 12003851 DOI: 10.1152/Ajpheart.00714.2001 |
0.531 |
|
| 2002 |
Wolska BM, Arteaga GM, Peña JR, Nowak G, Phillips RM, Sahai S, de Tombe PP, Martin AF, Kranias EG, Solaro RJ. Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation. Circulation Research. 90: 882-8. PMID 11988489 DOI: 10.1161/01.Res.0000016962.36404.04 |
0.397 |
|
| 2002 |
Communal C, Sumandea M, de Tombe P, Narula J, Solaro RJ, Hajjar RJ. Functional consequences of caspase activation in cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 6252-6. PMID 11972044 DOI: 10.1073/Pnas.092022999 |
0.454 |
|
| 2002 |
Solaro RJ. ST-H-1 Molecular mechanisms and therapeutics of myofilament Ca2+ — Sensitization Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90371-8 |
0.336 |
|
| 2002 |
Solaro RJ. IL-6 Integrated biology and molecular mechanisms of cardiac myofilament activation Journal of Molecular and Cellular Cardiology. 34. DOI: 10.1016/S0022-2828(02)90256-7 |
0.341 |
|
| 2001 |
Wolska BM, Vijayan K, Arteaga GM, Konhilas JP, Phillips RM, Kim R, Naya T, Leiden JM, Martin AF, de Tombe PP, Solaro RJ. Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions. The Journal of Physiology. 536: 863-70. PMID 11691878 DOI: 10.1111/J.1469-7793.2001.00863.X |
0.457 |
|
| 2001 |
Huang L, Wolska BM, Montgomery DE, Burkart EM, Buttrick PM, Solaro RJ. Increased contractility and altered Ca2+ transients of mouse heart myocytes conditionally expressing PKCβ American Journal of Physiology-Cell Physiology. 280. PMID 11287324 DOI: 10.1152/Ajpcell.2001.280.5.C1114 |
0.557 |
|
| 2001 |
Keller RS, Shai SY, Babbitt CJ, Pham CG, Solaro RJ, Valencik ML, Loftus JC, Ross RS. Disruption of integrin function in the murine myocardium leads to perinatal lethality, fibrosis, and abnormal cardiac performance American Journal of Pathology. 158: 1079-1090. PMID 11238056 DOI: 10.1016/S0002-9440(10)64055-2 |
0.487 |
|
| 2001 |
Montgomery DE, Chandra M, Huang QQ, Jin JP, Solaro RJ. Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force American Journal of Physiology - Heart and Circulatory Physiology. 280: H1011-H1018. PMID 11179042 DOI: 10.1152/Ajpheart.2001.280.3.H1011 |
0.486 |
|
| 2001 |
MacGowan GA, Du C, Cowan DB, Stamm C, McGowan FX, Solaro RJ, Koretsky AP, Del Nido PJ. Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites. American Journal of Physiology. Heart and Circulatory Physiology. 280: H835-43. PMID 11158984 DOI: 10.1152/Ajpheart.2001.280.2.H835 |
0.411 |
|
| 2001 |
Chandra M, Rundell VLM, Tardiff JC, Leinwand LA, De Tombe PP, Solaro RJ. Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin t American Journal of Physiology - Heart and Circulatory Physiology. 280: H705-H713. PMID 11158969 DOI: 10.1152/Ajpheart.2001.280.2.H705 |
0.409 |
|
| 2001 |
Pyle W, Half MC, Cooper JA, de Tombe PP, Solaro R. Cardiac actin capping protein is an essential element in protein kinase C signaling to the myofilament Journal of Molecular and Cellular Cardiology. 33: A97. DOI: 10.1016/S0022-2828(01)90386-4 |
0.429 |
|
| 2000 |
De Tombe PP, Solaro RJ. Integration of cardiac myofilament activity and regulation with pathways signaling hypertrophy and failure Annals of Biomedical Engineering. 28: 991-1001. PMID 11144684 DOI: 10.1114/1.1312189 |
0.423 |
|
| 2000 |
Evans CC, Pena JR, Phillips RM, Muthuchamy M, Wieczorek DF, Solaro RJ, Wolska BM. Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2414-23. PMID 11045979 DOI: 10.1152/Ajpheart.2000.279.5.H2414 |
0.476 |
|
| 2000 |
Solaro RJ. Myosin light chain phosphatase: A cinderella of cellular signaling Circulation Research. 87: 173-175. PMID 10926864 DOI: 10.1161/01.Res.87.3.173 |
0.44 |
|
| 2000 |
Arteaga GM, Palmiter KA, Leiden JM, Solaro RJ. Attenuation of length dependence of calcium activation in myofilaments of transgenic mouse hearts expressing slow skeletal troponin I. The Journal of Physiology. 526: 541-9. PMID 10922006 DOI: 10.1111/J.1469-7793.2000.T01-1-00541.X |
0.496 |
|
| 1999 |
Schwertz DW, Vizgirda V, Solaro RJ, Piano MR, Ryjewski C. Sexual dimorphism in rat left atrial function and response to adrenergic stimulation Molecular and Cellular Biochemistry. 200: 143-153. PMID 10569194 DOI: 10.1023/A:1007011807383 |
0.398 |
|
| 1999 |
Chandra M, Kim JJ, Solaro RJ. An improved method for exchanging troponin subunits in detergent skinned rat cardiac fiber bundles Biochemical and Biophysical Research Communications. 263: 219-223. PMID 10486280 DOI: 10.1006/Bbrc.1999.1341 |
0.383 |
|
| 1999 |
Finley N, Abbott MB, Abusamhadneh E, Gaponenko V, Dong W, Gasmi-Seabrook G, Howarth JW, Rance M, Solaro RJ, Cheung HC, Rosevear PR. NMR analysis of cardiac troponin C-troponin I complexes: effects of phosphorylation. Febs Letters. 453: 107-12. PMID 10403385 DOI: 10.1016/S0014-5793(99)00693-6 |
0.503 |
|
| 1999 |
Muthuchamy M, Pieples K, Rethinasamy P, Hoit B, Grupp IL, Boivin GP, Wolska B, Evans C, Solaro RJ, Wieczorek DF. Mouse model of a familial hypertrophic cardiomyopathy mutation in α- tropomyosin manifests cardiac dysfunction Circulation Research. 85: 47-56. PMID 10400910 DOI: 10.1161/01.Res.85.1.47 |
0.469 |
|
| 1999 |
Chandra M, Montgomery DE, Kim JJ, Solaro RJ. The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments Journal of Molecular and Cellular Cardiology. 31: 867-880. PMID 10329214 DOI: 10.1006/Jmcc.1999.0928 |
0.505 |
|
| 1999 |
Fentzke RC, Buck SH, Patel JR, Lin H, Wolska BM, Stojanovic MO, Martin AF, Solaro RJ, Moss RL, Leiden JM. Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart. The Journal of Physiology. 517: 143-57. PMID 10226156 DOI: 10.1111/J.1469-7793.1999.0143Z.X |
0.533 |
|
| 1999 |
Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ. Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin. Circulation Research. 84: 745-51. PMID 10205142 DOI: 10.1161/01.Res.84.7.745 |
0.44 |
|
| 1999 |
Rarick HM, Tang Hp, Guo XD, Martin AF, Solaro RJ. Interactions at the NH2-terminal interface of cardiac troponin I modulate myofilament activation Journal of Molecular and Cellular Cardiology. 31: 363-375. PMID 10093049 DOI: 10.1006/Jmcc.1998.0870 |
0.493 |
|
| 1998 |
Powers FM, Fogelson B, Sturgeon C, Solaro RJ, Law WR. Depressed myofilament co-operativity associated with post-cardioplegic myocardial depression Journal of Molecular and Cellular Cardiology. 30: 1779-1787. PMID 9769234 DOI: 10.1006/Jmcc.1998.0742 |
0.399 |
|
| 1998 |
Solaro RJ, Rarick HM. Troponin and tropomyosin: Proteins that switch on and tune in the activity of cardiac myofilaments Circulation Research. 83: 471-480. PMID 9734469 DOI: 10.1161/01.Res.83.5.471 |
0.52 |
|
| 1998 |
Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Circulation Research. 82: 261-71. PMID 9468197 DOI: 10.1161/01.Res.82.2.261 |
0.445 |
|
| 1998 |
Rethinasamy P, Muthuchamy M, Hewett T, Boivin G, Wolska BM, Evans C, Solaro RJ, Wieczorek DF. Molecular and physiological effects of α-tropomyosin ablation in the mouse Circulation Research. 82: 116-123. PMID 9440710 DOI: 10.1161/01.Res.82.1.116 |
0.37 |
|
| 1998 |
Arteaga GM, Lap SD, Wolska BM, Kecskes S, Solaro RJ. Functional studies in human cardiac tissue obtained from endomyocardial biopsies Critical Care Medicine. 26. DOI: 10.1097/00003246-199801001-00144 |
0.378 |
|
| 1998 |
Kitada Y, Solaro RJ. The role of phosphorylation of troponin T and I by protein kinase a or c -dependent pathway in the myofilament Ca2+-sensitizing effects of MCI-154 and levosimendan Journal of Cardiac Failure. 4: 102. DOI: 10.1016/S1071-9164(98)90440-7 |
0.409 |
|
| 1998 |
Solaro RJ. Heart failure and molecular signaling in cardiac myofilaments Journal of Cardiac Failure. 4: 41-42. DOI: 10.1016/S1071-9164(98)90278-0 |
0.456 |
|
| 1997 |
Fraker LD, Eyk VJ, Solaro RJ. Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle Molecular and Cellular Biochemistry. 176: 83-88. PMID 9406148 DOI: 10.1023/A:1006827012495 |
0.353 |
|
| 1997 |
Wolska BM, Averyhart-Fullard V, Omachi A, Stojanović MO, Kallen RG, Solaro RJ. Changes in Thyroid State Affect pHiand Nai+Homeostasis in Rat Ventricular Myocytes Journal of Molecular and Cellular Cardiology. 29: 2653-2663. PMID 9344760 DOI: 10.1006/Jmcc.1997.0495 |
0.45 |
|
| 1996 |
Rarick HM, Opgenorth TJ, Von Geldern TW, Wu-Wong JR, Solaro RJ. An essential myosin light chain peptide induces supramaximal stimulation of cardiac myofibrillar ATPase activity Journal of Biological Chemistry. 271: 27039-27043. PMID 8900193 DOI: 10.1074/Jbc.271.43.27039 |
0.408 |
|
| 1996 |
Palmiter KA, Kitada Y, Muthuchamy M, Wieczorek DF, Solaro RJ. Exchange of β- for α-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation Journal of Biological Chemistry. 271: 11611-11614. PMID 8662805 DOI: 10.1074/Jbc.271.20.11611 |
0.508 |
|
| 1996 |
Luo W, Wolska BM, Grupp IL, Harrer JM, Haghighi K, Ferguson DG, Slack JP, Grupp G, Doetschman T, Solaro RJ, Kranias EG. Phospholamban gene dosage effects in the mammalian heart. Circulation Research. 78: 839-47. PMID 8620604 DOI: 10.1161/01.Res.78.5.839 |
0.55 |
|
| 1996 |
Powers FM, Palmiter KA, Solaro RJ. E-1020, A Water Soluble Imidazopyridine, Has Direct Effects On Ca2+-Dependent Force And Atp Hydrolysis Of Canine And Bovine Cardiac Myofilaments Molecular and Cellular Biochemistry. 160: 33-39. DOI: 10.1007/978-1-4613-1279-6_4 |
0.446 |
|
| 1995 |
Edes I, Kiss E, Kitada Y, Powers FM, Papp JG, Kranias EG, Solaro RJ. Effects of Levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart. Circulation Research. 77: 107-13. PMID 7788868 DOI: 10.1161/01.Res.77.1.107 |
0.518 |
|
| 1992 |
Solaro RJ. Modulation of the response of cardiac myofilaments to Ca2 Journal of Molecular and Cellular Cardiology. 24: 12. DOI: 10.1016/0022-2828(92)90067-A |
0.457 |
|
| 1991 |
Solaro RJ. Functional significance of differences in isoform population of thin filament proteins in developing heart Journal of Molecular and Cellular Cardiology. 23. DOI: 10.1016/0022-2828(91)91369-3 |
0.409 |
|
| 1989 |
Solaro RJ, El-Salehl SC, Kentish JC. Ca2+, pH and the regulation of cardiac myofilament force and ATPase activity Molecular and Cellular Biochemistry. 89: 163-167. PMID 2530435 DOI: 10.1007/Bf00220770 |
0.411 |
|
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