| Year |
Citation |
Score |
| 2020 |
Gonda TA, Fang J, Salas M, Do C, Hsu E, Zhukovskaya A, Siegel A, Takahashi R, Lopez-Bujanda ZA, Drake CG, Manji GA, Wang TC, Olive KP, Tycko B. A DNA hypomethylating drug alters the tumor microenvironment and improves the effectiveness of immune checkpoint inhibitors in a mouse model of pancreatic cancer. Cancer Research. PMID 32816859 DOI: 10.1158/0008-5472.Can-20-0285 |
0.729 |
|
| 2020 |
Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, ... ... Tycko B, et al. Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs. Genome Biology. 21: 153. PMID 32594908 DOI: 10.1186/S13059-020-02059-3 |
0.331 |
|
| 2020 |
Yu YE, Xing Z, Do C, Pao A, Lee EJ, Krinsky-McHale S, Silverman W, Schupf N, Tycko B. Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models. Progress in Brain Research. 251: 1-28. PMID 32057305 DOI: 10.1016/Bs.Pbr.2019.09.002 |
0.355 |
|
| 2018 |
Delahaye F, Do C, Kong Y, Ashkar R, Salas M, Tycko B, Wapner R, Hughes F. Genetic variants influence on the placenta regulatory landscape. Plos Genetics. 14: e1007785. PMID 30452450 DOI: 10.1371/Journal.Pgen.1007785 |
0.34 |
|
| 2018 |
Youn A, Kim KI, Rabadan R, Tycko B, Shen Y, Wang S. A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes. Bmc Medical Genomics. 11: 98. PMID 30400878 DOI: 10.1186/S12920-018-0425-Z |
0.306 |
|
| 2018 |
Wu HC, Do C, Andrulis IL, John EM, Daly MB, Buys SS, Chung WK, Knight JA, Bradbury AR, Keegan THM, Schwartz L, Krupska I, Miller RL, Santella RM, Tycko B, et al. Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study. Epigenetics. 1-23. PMID 29436922 DOI: 10.1080/15592294.2018.1435243 |
0.331 |
|
| 2018 |
Safyan RA, Gonda T, Tycko B, Chabot JA, Manji GA, Schwartz GK, Oberstein PE. Phase II open-label, single-center study evaluating safety and efficacy of pembrolizumab following induction with the hypomethylating agent azacitidine in patients with advanced pancreatic cancer after failure of first-line therapy. Journal of Clinical Oncology. 36: TPS534-TPS534. DOI: 10.1200/Jco.2018.36.4_Suppl.Tps534 |
0.329 |
|
| 2017 |
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Tycko B, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/Ng.3906 |
0.306 |
|
| 2017 |
Do C, Shearer A, Suzuki M, Terry MB, Gelernter J, Greally JM, Tycko B. Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era. Genome Biology. 18: 120. PMID 28629478 DOI: 10.1186/S13059-017-1250-Y |
0.312 |
|
| 2017 |
Lee JH, Lee AJ, Dang LH, Pang D, Kisselev S, Krinsky-McHale SJ, Zigman WB, Luchsinger JA, Silverman W, Tycko B, Clark LN, Schupf N. Candidate gene analysis for Alzheimer's disease in adults with Down syndrome. Neurobiology of Aging. PMID 28554490 DOI: 10.1016/J.Neurobiolaging.2017.04.018 |
0.339 |
|
| 2017 |
Yotova I, Hsu E, Do C, Gaba A, Sczabolcs M, Dekan S, Kenner L, Wenzl R, Tycko B. Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis. Plos One. 12: e0170859. PMID 28125717 DOI: 10.1371/Journal.Pone.0170859 |
0.358 |
|
| 2016 |
Do C, Xing Z, Yu YE, Tycko B. Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models. Epigenomics. PMID 27911079 DOI: 10.2217/Epi-2016-0138 |
0.329 |
|
| 2016 |
Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, ... Tycko B, et al. Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation. American Journal of Human Genetics. 98: 934-55. PMID 27153397 DOI: 10.1016/J.Ajhg.2016.03.027 |
0.334 |
|
| 2016 |
Gonda T, Fang J, Do C, Zhukovskaya A, Salas M, Tycko B. Abstract 3213: Hypomethylation therapy leads to immune polarization and improved efficacy of immunotherapy in transgenic model of pancreatic cancer Cancer Research. 76: 3213-3213. DOI: 10.1158/1538-7445.Am2016-3213 |
0.73 |
|
| 2015 |
Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, ... ... Tycko B, et al. Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models. Genome Biology. 16: 263. PMID 26607552 DOI: 10.1186/S13059-015-0827-6 |
0.345 |
|
| 2015 |
Schupf N, Lee A, Park N, Dang LH, Pang D, Yale A, Oh DK, Krinsky-McHale SJ, Jenkins EC, Luchsinger JA, Zigman WB, Silverman W, Tycko B, Kisselev S, Clark L, et al. Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome. Neurobiology of Aging. PMID 26166206 DOI: 10.1016/J.Neurobiolaging.2015.06.020 |
0.31 |
|
| 2014 |
Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, ... Tycko B, et al. PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: E2404-13. PMID 24912192 DOI: 10.1073/Pnas.1319962111 |
0.364 |
|
| 2014 |
Maldonado L, Diaz-Montes T, Sinno A, Tanner EJ, VandenBussche C, Roden R, Yotova I, Tycko B, Trimble CL. Abstract 3672: Role and presence of cancer associated fibroblasts and M2 macrophages in high grade cervical intraepithelial neoplasia and invasive cervical carcinomas Cancer Research. 74: 3672-3672. DOI: 10.1158/1538-7445.Am2014-3672 |
0.307 |
|
| 2013 |
Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, ... ... Tycko B, et al. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation. Plos Genetics. 9: e1003622. PMID 24009515 DOI: 10.1371/Journal.Pgen.1003622 |
0.332 |
|
| 2013 |
Narayan G, Xie D, Freddy AJ, Ishdorj G, Do C, Satwani P, Liyanage H, Clark L, Kisselev S, Nandula SV, Scotto L, Alobeid B, Savage D, Tycko B, O'Connor OA, et al. PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis. Genes, Chromosomes & Cancer. 52: 1030-41. PMID 23929756 DOI: 10.1002/Gcc.22098 |
0.334 |
|
| 2013 |
Shakya R, Gonda T, Quante M, Salas M, Kim S, Brooks J, Hirsch S, Davies J, Cullo A, Olive K, Wang TC, Szabolcs M, Tycko B, Ludwig T. Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Research. 73: 885-96. PMID 23204224 DOI: 10.1158/0008-5472.Can-12-1880 |
0.383 |
|
| 2013 |
Xing L, Salas M, Zhang H, Gittler J, Ludwig T, Lin CS, Murty VV, Silverman W, Arancio O, Tycko B. Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 30-43. PMID 23096997 DOI: 10.1007/S00335-012-9436-9 |
0.326 |
|
| 2013 |
Tycko B. Abstract ED02-02: Interaction between genetics, epigenetics, and environment in cancer prevention Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Ed02-02 |
0.332 |
|
| 2013 |
Lee S, Galili N, Nimer S, Minden MD, Murty VV, Jhanwar S, Raza A, Tycko B. Abstract 2989: Loss of methylation in a regulatory region of BCL2 in MDS/AML. Cancer Research. 73: 2989-2989. DOI: 10.1158/1538-7445.Am2013-2989 |
0.323 |
|
| 2012 |
Gonda TA, Kim YI, Salas MC, Gamble MV, Shibata W, Muthupalani S, Sohn KJ, Abrams JA, Fox JG, Wang TC, Tycko B. Folic acid increases global DNA methylation and reduces inflammation to prevent Helicobacter-associated gastric cancer in mice. Gastroenterology. 142: 824-833.e7. PMID 22248660 DOI: 10.1053/J.Gastro.2011.12.058 |
0.31 |
|
| 2012 |
Chace C, Pang D, Weng C, Temkin A, Lax S, Silverman W, Zigman W, Ferin M, Lee JH, Tycko B, Schupf N. Variants in CYP17 and CYP19 cytochrome P450 genes are associated with onset of Alzheimer's disease in women with down syndrome. Journal of Alzheimer's Disease : Jad. 28: 601-12. PMID 22057025 DOI: 10.3233/Jad-2011-110860 |
0.302 |
|
| 2011 |
Kalac M, Scotto L, Marchi E, Amengual J, Seshan VE, Bhagat G, Ulahannan N, Leshchenko VV, Temkin AM, Parekh S, Tycko B, O'Connor OA. HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL. Blood. 118: 5506-16. PMID 21772049 DOI: 10.1182/Blood-2011-02-336891 |
0.355 |
|
| 2011 |
Quante M, Tu SP, Tomita H, Gonda T, Wang SS, Takashi S, Baik GH, Shibata W, Diprete B, Betz KS, Friedman R, Varro A, Tycko B, Wang TC. Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell. 19: 257-72. PMID 21316604 DOI: 10.1016/J.Ccr.2011.01.020 |
0.323 |
|
| 2010 |
Kerkel K, Schupf N, Hatta K, Pang D, Salas M, Kratz A, Minden M, Murty V, Zigman WB, Mayeux RP, Jenkins EC, Torkamani A, Schork NJ, Silverman W, Croy BA, ... Tycko B, et al. Altered DNA methylation in leukocytes with trisomy 21. Plos Genetics. 6: e1001212. PMID 21124956 DOI: 10.1371/Journal.Pgen.1001212 |
0.363 |
|
| 2010 |
Tycko B. Allele-specific DNA methylation: beyond imprinting. Human Molecular Genetics. 19: R210-20. PMID 20855472 DOI: 10.1093/Hmg/Ddq376 |
0.35 |
|
| 2010 |
Tycko B. Mapping allele-specific DNA methylation: a new tool for maximizing information from GWAS. American Journal of Human Genetics. 86: 109-12. PMID 20159108 DOI: 10.1016/J.Ajhg.2010.01.021 |
0.336 |
|
| 2010 |
Gonda TA, Varro A, Wang TC, Tycko B. Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Seminars in Cell & Developmental Biology. 21: 2-10. PMID 19840860 DOI: 10.1016/J.Semcdb.2009.10.001 |
0.316 |
|
| 2010 |
Kalac M, Marchi E, Scotto L, Amengual J, Seshan V, Bhagat G, Ulahannan N, Leshchenko V, Parekh S, Tycko B, O'Connor OA. Synergistic Combinations of Histone Deacetylase Inhibitors and Decitabine Induce a Unique Gene Expression and Epigenetic Profile In Models of Diffuse Large B-Cell Lymphoma Blood. 116: 435-435. DOI: 10.1182/Blood.V116.21.435.435 |
0.355 |
|
| 2010 |
Quante M, Tu S, Tomita H, Gonda T, Tycko B, Wang TC. Abstract 1427: Mesenchymal stem cells derived myofibroblasts function as niche cells in the normal bone marrow and expand during carcinogenesis to promote tumor growth Cancer Research. 70: 1427-1427. DOI: 10.1158/1538-7445.Am10-1427 |
0.309 |
|
| 2008 |
Jiang L, Gonda TA, Gamble MV, Salas M, Seshan V, Tu S, Twaddell WS, Hegyi P, Lazar G, Steele I, Varro A, Wang TC, Tycko B. Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Research. 68: 9900-8. PMID 19047171 DOI: 10.1158/0008-5472.Can-08-1319 |
0.331 |
|
| 2008 |
Kerkel K, Spadola A, Yuan E, Kosek J, Jiang L, Hod E, Li K, Murty VV, Schupf N, Vilain E, Morris M, Haghighi F, Tycko B. Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation. Nature Genetics. 40: 904-8. PMID 18568024 DOI: 10.1038/Ng.174 |
0.326 |
|
| 2008 |
Schupf N, Lee JH, Wei M, Pang D, Chace C, Cheng R, Zigman WB, Tycko B, Silverman W. Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome. Dementia and Geriatric Cognitive Disorders. 25: 476-82. PMID 18408366 DOI: 10.1159/000126495 |
0.31 |
|
| 2008 |
Kim MK, Mason JM, Li CM, Berkofsky-Fessler W, Jiang L, Choubey D, Grundy PE, Tycko B, Licht JD. A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16. Neoplasia (New York, N.Y.). 10: 69-78. PMID 18231640 DOI: 10.1593/Neo.07869 |
0.364 |
|
| 2007 |
Tycko B, Li CM, Buttyan R. The Wnt/beta-catenin pathway in Wilms tumors and prostate cancers. Current Molecular Medicine. 7: 479-89. PMID 17691963 DOI: 10.2174/156652407781387118 |
0.312 |
|
| 2007 |
Xing L, Salas M, Lin CS, Zigman W, Silverman W, Subramaniyam S, Murty VV, Tycko B. Faithful tissue-specific expression of the human chromosome 21-linked COL6A1 gene in BAC-transgenic mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 113-22. PMID 17334655 DOI: 10.1007/S00335-006-0082-Y |
0.319 |
|
| 2007 |
Kim HS, Roh CR, Chen B, Tycko B, Nelson DM, Sadovsky Y. Hypoxia regulates the expression of PHLDA2 in primary term human trophoblasts. Placenta. 28: 77-84. PMID 16584773 DOI: 10.1016/J.Placenta.2006.01.025 |
0.309 |
|
| 2006 |
Yuan E, Haghighi F, White S, Costa R, McMinn J, Chun K, Minden M, Tycko B. A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons. Cancer Research. 66: 3443-51. PMID 16585166 DOI: 10.1158/0008-5472.Can-05-3739 |
0.346 |
|
| 2006 |
Tycko B. Imprinted genes in placental growth and obstetric disorders. Cytogenetic and Genome Research. 113: 271-8. PMID 16575190 DOI: 10.1159/000090842 |
0.338 |
|
| 2006 |
Li CM, Guo M, Salas M, Schupf N, Silverman W, Zigman WB, Husain S, Warburton D, Thaker H, Tycko B. Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. Bmc Medical Genetics. 7: 24. PMID 16539728 DOI: 10.1186/1471-2350-7-24 |
0.306 |
|
| 2006 |
Li CM, Margolin AA, Salas M, Memeo L, Mansukhani M, Hibshoosh H, Szabolcs M, Klinakis A, Tycko B. PEG10 is a c-MYC target gene in cancer cells. Cancer Research. 66: 665-72. PMID 16423995 DOI: 10.1158/0008-5472.Can-05-1553 |
0.322 |
|
| 2006 |
McMinn J, Wei M, Sadovsky Y, Thaker HM, Tycko B. Imprinting of PEG1/MEST isoform 2 in human placenta. Placenta. 27: 119-26. PMID 16338457 DOI: 10.1016/J.Placenta.2004.12.003 |
0.336 |
|
| 2006 |
McMinn J, Wei M, Schupf N, Cusmai J, Johnson EB, Smith AC, Weksberg R, Thaker HM, Tycko B. Unbalanced placental expression of imprinted genes in human intrauterine growth restriction. Placenta. 27: 540-9. PMID 16125225 DOI: 10.1016/J.Placenta.2005.07.004 |
0.336 |
|
| 2005 |
Yuan E, Li CM, Yamashiro DJ, Kandel J, Thaker H, Murty VV, Tycko B. Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors. Molecular Cancer Research : McR. 3: 493-502. PMID 16179496 DOI: 10.1158/1541-7786.Mcr-05-0082 |
0.342 |
|
| 2005 |
Jakob J, Nagase S, Gazdar A, Chien M, Morozova I, Russo JJ, Nandula SV, Murty VV, Li CM, Tycko B, Parsons R. Two somatic biallelic lesions within and near SMAD4 in a human breast cancer cell line. Genes, Chromosomes & Cancer. 42: 372-83. PMID 15645498 DOI: 10.1002/Gcc.20142 |
0.324 |
|
| 2004 |
Li CM, Kim CE, Margolin AA, Guo M, Zhu J, Mason JM, Hensle TW, Murty VV, Grundy PE, Fearon ER, D'Agati V, Licht JD, Tycko B. CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors. The American Journal of Pathology. 165: 1943-53. PMID 15579438 DOI: 10.1016/S0002-9440(10)63246-4 |
0.3 |
|
| 2004 |
Tycko B, Lee JH, Ciappa A, Saxena A, Li CM, Feng L, Arriaga A, Stern Y, Lantigua R, Shachter N, Mayeux R. APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals. Archives of Neurology. 61: 1434-9. PMID 15364690 DOI: 10.1001/Archneur.61.9.1434 |
0.305 |
|
| 2004 |
Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B. Placental growth retardation due to loss of imprinting of Phlda2. Mechanisms of Development. 121: 1199-210. PMID 15327781 DOI: 10.1016/J.Mod.2004.05.017 |
0.324 |
|
| 2004 |
Li Q, Athan ES, Wei M, Yuan E, Rice SL, Vonsattel JP, Mayeux RP, Tycko B. TP73 allelic expression in human brain and allele frequencies in Alzheimer's disease. Bmc Medical Genetics. 5: 14. PMID 15175114 DOI: 10.1186/1471-2350-5-14 |
0.34 |
|
| 2003 |
Tycko B. Genetic and epigenetic mosaicism in cancer precursor tissues. Annals of the New York Academy of Sciences. 983: 43-54. PMID 12724211 DOI: 10.1111/J.1749-6632.2003.Tb05961.X |
0.309 |
|
| 2003 |
Goldberg M, Wei M, Yuan L, Murty VV, Tycko B. Biallelic expression of HRAS and MUCDHL in human and mouse. Human Genetics. 112: 334-42. PMID 12589428 DOI: 10.1007/S00439-003-0907-7 |
0.374 |
|
| 2002 |
Athan ES, Lee JH, Arriaga A, Mayeux RP, Tycko B. Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease. Archives of Neurology. 59: 1793-9. PMID 12433268 DOI: 10.1001/Archneur.59.11.1793 |
0.313 |
|
| 2002 |
Lynch CA, Tycko B, Bestor TH, Walsh CP. Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. Molecular Cancer. 1: 2. PMID 12234381 DOI: 10.1186/1476-4598-1-2 |
0.337 |
|
| 2002 |
Yeh A, Wei M, Golub SB, Yamashiro DJ, Murty VV, Tycko B. Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene. Genes, Chromosomes & Cancer. 35: 156-63. PMID 12203779 DOI: 10.1002/Gcc.10110 |
0.339 |
|
| 2002 |
Tycko B, Morison IM. Physiological functions of imprinted genes. Journal of Cellular Physiology. 192: 245-58. PMID 12124770 DOI: 10.1002/Jcp.10129 |
0.316 |
|
| 2002 |
Clark L, Wei M, Cattoretti G, Mendelsohn C, Tycko B. The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface. Bmc Genetics. 3: 11. PMID 12102730 DOI: 10.1186/1471-2156-3-11 |
0.323 |
|
| 2002 |
Li CM, Guo M, Borczuk A, Powell CA, Wei M, Thaker HM, Friedman R, Klein U, Tycko B. Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. The American Journal of Pathology. 160: 2181-90. PMID 12057921 DOI: 10.1016/S0002-9440(10)61166-2 |
0.334 |
|
| 2002 |
Frank D, Fortino W, Clark L, Musalo R, Wang W, Saxena A, Li CM, Reik W, Ludwig T, Tycko B. Placental overgrowth in mice lacking the imprinted gene Ipl. Proceedings of the National Academy of Sciences of the United States of America. 99: 7490-5. PMID 12032310 DOI: 10.1073/Pnas.122039999 |
0.323 |
|
| 2001 |
Sakatani T, Wei M, Katoh M, Okita C, Wada D, Mitsuya K, Meguro M, Ikeguchi M, Ito H, Tycko B, Oshimura M. Epigenetic heterogeneity at imprinted loci in normal populations. Biochemical and Biophysical Research Communications. 283: 1124-30. PMID 11355889 DOI: 10.1006/Bbrc.2001.4916 |
0.334 |
|
| 2000 |
Tycko B. Epigenetic gene silencing in cancer. The Journal of Clinical Investigation. 105: 401-7. PMID 10683367 DOI: 10.1172/Jci9462 |
0.355 |
|
| 2000 |
Tycko B, Ashkenas J. Epigenetics and its role in disease. The Journal of Clinical Investigation. 105: 245-6. PMID 10675348 DOI: 10.1172/Jci9319 |
0.386 |
|
| 1999 |
Frank D, Mendelsohn CL, Ciccone E, Svensson K, Ohlsson R, Tycko B. A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 1150-9. PMID 10594239 DOI: 10.1007/S003359901182 |
0.335 |
|
| 1999 |
Dao D, Walsh CP, Yuan L, Gorelov D, Feng L, Hensle T, Nisen P, Yamashiro DJ, Bestor TH, Tycko B. Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Human Molecular Genetics. 8: 1337-52. PMID 10369881 DOI: 10.1093/Hmg/8.7.1337 |
0.352 |
|
| 1998 |
Dao D, Frank D, Qian N, O'Keefe D, Vosatka RJ, Walsh CP, Tycko B. IMPT1, an imprinted gene similar to polyspecific transporter and multi-drug resistance genes. Human Molecular Genetics. 7: 597-608. PMID 9499412 DOI: 10.1093/Hmg/7.4.597 |
0.33 |
|
| 1997 |
Isfort RJ, Cody DB, Kerckaert GA, Tycko B, LeBoeuf RA. Role of the H19 gene in Syrian hamster embryo cell tumorigenicity. Molecular Carcinogenesis. 20: 189-93. PMID 9364208 DOI: 10.1002/(Sici)1098-2744(199710)20:2<189::Aid-Mc5>3.0.Co;2-I |
0.329 |
|
| 1997 |
Qian N, Frank D, O'Keefe D, Dao D, Zhao L, Yuan L, Wang Q, Keating M, Walsh C, Tycko B. The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis. Human Molecular Genetics. 6: 2021-9. PMID 9328465 DOI: 10.1093/Hmg/6.12.2021 |
0.344 |
|
| 1997 |
O'Keefe D, Dao D, Zhao L, Sanderson R, Warburton D, Weiss L, Anyane-Yeboa K, Tycko B. Coding mutations in p57(KIP2) are present in some cases of Beckwith- Wiedemann syndrome but are rare or absent in Wilms tumors American Journal of Human Genetics. 61: 295-303. PMID 9311733 DOI: 10.1086/514854 |
0.338 |
|
| 1997 |
Tycko B. DNA methylation in genomic imprinting. Mutation Research. 386: 131-40. PMID 9113114 DOI: 10.1016/S1383-5742(96)00049-X |
0.369 |
|
| 1997 |
Chung WY, Yuan L, Feng L, Hensle T, Tycko B. Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors. Human Molecular Genetics. 5: 1101-8. PMID 8842727 DOI: 10.1093/Hmg/5.8.1101 |
0.367 |
|
| 1996 |
Yuan L, Qian N, Tycko B. An extended region of biallelic gene expression and rodent-human synteny downstream of the imprinted H19 gene on chromosome 11p15.5. Human Molecular Genetics. 5: 1931-7. PMID 8968746 DOI: 10.1093/Hmg/5.12.1931 |
0.325 |
|
| 1996 |
Moulton T, Chung WY, Yuan L, Hensle T, Waber P, Nisen P, Tycko B. Genomic imprinting and Wilms' tumor. Medical and Pediatric Oncology. 27: 476-83. PMID 8827077 DOI: 10.1002/(Sici)1096-911X(199611)27:5<476::Aid-Mpo15>3.0.Co;2-8 |
0.379 |
|
| 1996 |
Tycko B, Feng L, Nguyen L, Francis A, Hays A, Chung WY, Tang MX, Stern Y, Sahota A, Hendrie H, Mayeux R. Polymorphisms in the human apolipoprotein-J/clusterin gene: ethnic variation and distribution in Alzheimer's disease. Human Genetics. 98: 430-6. PMID 8792817 DOI: 10.1007/S004390050234 |
0.306 |
|
| 1995 |
Tsang P, Gilles F, Yuan L, Kuo Y, Lupu F, Samara G, Moosikasuwan J, Goye A, Zelenetz AD, Selleri L, Tycko B. A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues Human Molecular Genetics. 4: 1499-1507. PMID 8541832 DOI: 10.1093/Hmg/4.9.1499 |
0.338 |
|
| 1993 |
Hao Y, Crenshaw T, Moulton T, Newcomb E, Tycko B. Tumour-suppressor activity of H19 RNA. Nature. 365: 764-7. PMID 7692308 DOI: 10.1038/365764A0 |
0.324 |
|
| 1993 |
Zhang Y, Tycko B. Monoallelic expression of the human H19 gene. Nature Genetics. 1: 40-4. PMID 1363808 DOI: 10.1038/Ng0492-40 |
0.332 |
|
| 1984 |
DiPaola M, Keith CH, Feldman D, Tycko B, Maxfield FR. Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides. Journal of Cellular Physiology. 118: 193-202. PMID 6319437 DOI: 10.1002/Jcp.1041180212 |
0.497 |
|
| 1984 |
Yamashiro DJ, Tycko B, Fluss SR, Maxfield FR. Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell. 37: 789-800. PMID 6204769 DOI: 10.1016/0092-8674(84)90414-8 |
0.482 |
|
| 1983 |
Tycko B, Keith CH, Maxfield FR. Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. The Journal of Cell Biology. 97: 1762-76. PMID 6315742 DOI: 10.1083/Jcb.97.6.1762 |
0.486 |
|
| 1983 |
Tycko B, DiPaola M, Yamashiro DJ, Fluss S, Maxfield FR. Acidification of endocytic vesicles and the intracellular pathways of ligands and receptors. Annals of the New York Academy of Sciences. 421: 424-33. PMID 6202216 DOI: 10.1111/J.1749-6632.1983.Tb18136.X |
0.46 |
|
| 1982 |
Tycko B, Maxfield FR. Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell. 28: 643-51. PMID 6176331 DOI: 10.1016/0092-8674(82)90219-7 |
0.475 |
|
| 1982 |
Anderson P, Tycko B, Maxfield F, Vilček J. Effect of primary amines on interferon action Virology. 117: 510-515. PMID 6175094 DOI: 10.1016/0042-6822(82)90491-3 |
0.496 |
|
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