Willem-Hendrik Gispen, Ph.D. - Publications

Affiliations: 
Medical pharmacology Utrecht University, Utrecht, Netherlands 
Area:
Molecular pharmacology en neuropharmacology
Website:
https://profs.library.uu.nl/index.php/profrec/getprofdata/678/55/133/0

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GAA, Van Wimersma Greidanus TB, Witter A, de Wied D. γ -Melanotropin and Brain Function Peptides of the Pars Intermedia. 263-276. DOI: 10.1002/9780470720646.ch15  0.729
2003 Ruitenberg MJ, Plant GW, Hamers FP, Wortel J, Blits B, Dijkhuizen PA, Gispen WH, Boer GJ, Verhaagen J. Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7045-58. PMID 12904465  0.626
2002 De Winter F, Oudega M, Lankhorst AJ, Hamers FP, Blits B, Ruitenberg MJ, Pasterkamp RJ, Gispen WH, Verhaagen J. Injury-induced class 3 semaphorin expression in the rat spinal cord. Experimental Neurology. 175: 61-75. PMID 12009760 DOI: 10.1006/exnr.2002.7884  0.612
2000 Brook GA, Houweling DA, Gieling RG, Hermanns T, Joosten EA, Bär DP, Gispen WH, Schmitt AB, Leprince P, Noth J, Nacimiento W. Attempted endogenous tissue repair following experimental spinal cord injury in the rat: involvement of cell adhesion molecules L1 and NCAM? The European Journal of Neuroscience. 12: 3224-38. PMID 10998106 DOI: 10.1046/J.1460-9568.2000.00228.X  0.734
1999 Holtmaat AJ, Huizinga CT, Margolis FL, Gispen WH, Verhaagen J. Transgenic expression of B-50/GAP-43 in mature olfactory neurons triggers downregulation of native B-50/GAP-43 expression in immature olfactory neurons. Brain Research. Molecular Brain Research. 74: 197-207. PMID 10640691 DOI: 10.1016/S0169-328X(99)00263-6  0.786
1998 Aarts LH, Schotman P, Verhaagen J, Schrama LH, Gispen WH. The role of the neural growth associated protein B-50/GAP-43 in morphogenesis. Advances in Experimental Medicine and Biology. 446: 85-106. PMID 10079839 DOI: 10.1007/978-1-4615-4869-0_6  0.604
1998 Duckers HJ, van Dokkum RP, Verhaagen J, van Luijtelaar EL, Coenen AM, Lopes da Silva FH, Gispen WH. Neurotrophic ACTH4-9 analogue therapy normalizes electroencephalographic alterations in chronic experimental allergic encephalomyelitis. The European Journal of Neuroscience. 10: 3709-20. PMID 9875350 DOI: 10.1046/j.1460-9568.1998.00382.x  0.627
1998 Holtmaat AJ, Oestreicher AB, Gispen WH, Verhaagen J. Manipulation of gene expression in the mammalian nervous system: application in the study of neurite outgrowth and neuroregeneration-related proteins. Brain Research. Brain Research Reviews. 26: 43-71. PMID 9600624 DOI: 10.1016/S0165-0173(97)00044-1  0.776
1997 Oestreicher AB, De Graan PN, Gispen WH, Verhaagen J, Schrama LH. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Progress in Neurobiology. 53: 627-86. PMID 9447616 DOI: 10.1016/S0301-0082(97)00043-9  0.633
1997 Buffo A, Holtmaat AJ, Savio T, Verbeek JS, Oberdick J, Oestreicher AB, Gispen WH, Verhaagen J, Rossi F, Strata P. Targeted overexpression of the neurite growth-associated protein B-50/GAP-43 in cerebellar Purkinje cells induces sprouting after axotomy but not axon regeneration into growth-permissive transplants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8778-91. PMID 9348347 DOI: 10.1523/Jneurosci.17-22-08778.1997  0.793
1997 Holtmaat AJ, Hermens WT, Sonnemans MA, Giger RJ, Van Leeuwen FW, Kaplitt MG, Oestreicher AB, Gispen WH, Verhaagen J. Adenoviral vector-mediated expression of B-50/GAP-43 induces alterations in the membrane organization of olfactory axon terminals in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6575-86. PMID 9254670 DOI: 10.1523/Jneurosci.17-17-06575.1997  0.787
1997 Duckers HJ, Muller HJ, Verhaagen J, Nicolay K, Gispen WH. Longitudinal in vivo magnetic resonance imaging studies in experimental allergic encephalomyelitis: effect of a neurotrophic treatment on cortical lesion development. Neuroscience. 77: 1163-73. PMID 9130795 DOI: 10.1016/S0306-4522(96)00514-3  0.604
1996 Duckers HJ, van Dokkum RP, Verhaagen J, Lopes da Silva FH, Gispen WH. Functional and neurophysiological evidence of the efficacy of trophic pharmacotherapy using an adrenocorticotrophic hormone4-9 analog in experimental allergic encephalomyelitis, an animal model of multiple sclerosis. Neuroscience. 71: 507-21. PMID 9053803 DOI: 10.1016/0306-4522(95)00451-3  0.642
1996 Holtmaat AJ, Hermens WT, Oestreicher AB, Gispen WH, Kaplitt MG, Verhaagen J. Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium. Brain Research. Molecular Brain Research. 41: 148-56. PMID 8883946 DOI: 10.1016/0169-328X(96)00085-X  0.769
1996 van Rijzingen IM, Gispen WH, Spruijt BM. The ACTH(4-9) analog ORG 2766 and recovery after brain damage in animal models--a review. Behavioural Brain Research. 74: 1-15. PMID 8851911 DOI: 10.1016/0166-4328(95)00039-9  0.345
1996 Ulenkate HJ, Gispen WH, Jennekens FG. Effects of ciliary neurotrophic factor on retrograde cell reaction after facial nerve crush in young adult rats. Brain Research. 717: 29-37. PMID 8738250 DOI: 10.1016/0006-8993(95)01512-4  0.628
1996 Hamers FP, Plantinga LC, Verhaagen J, Neijt JP, Gispen WH. Upregulation of B50/GAP-43 protein mRNA in rat dorsal root ganglia during cisplatin intoxication. Journal of Neuroscience Research. 44: 142-8. PMID 8723222 DOI: 10.1002/(SICI)1097-4547(19960415)44:2<142::AID-JNR6>3.0.CO;2-D  0.657
1995 Ulenkate HJ, Gispen WH, Jennekens FG. No evidence for enhancement of recovery from a crush lesion of a motor nerve in rats by Org2766. Restorative Neurology and Neuroscience. 9: 85-91. PMID 21551836 DOI: 10.3233/Rnn-1995-9203  0.61
1995 Chepkova AN, French P, De Wied D, Ontskul AH, Ramakers GM, Skrebitski VG, Gispen WH, Urban IJ. Long-lasting enhancement of synaptic excitability of CA1/subiculum neurons of the rat ventral hippocampus by vasopressin and vasopressin(4-8). Brain Research. 701: 255-66. PMID 8925289 DOI: 10.1016/0006-8993(95)01006-7  0.606
1995 Verhaagen J, Hermens WT, Dijkhuizen PA, Holtmaat AJ, Gispen WH. Use of viral vectors to promote neuroregeneration. Clinical Neuroscience (New York, N.Y.). 3: 275-83. PMID 8914794  0.771
1995 Holtmaat AJ, Dijkhuizen PA, Oestreicher AB, Romijn HJ, Van der Lugt NM, Berns A, Margolis FL, Gispen WH, Verhaagen J. Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7953-65. PMID 8613733 DOI: 10.1523/Jneurosci.15-12-07953.1995  0.794
1995 Zhang YP, Verhaagen J, Hamers FP, Gispen WH. [Elevated expression of B-50 (GAP-43) -mRNA in a subpopulation of olfactory bulb mitral cells following axotomy]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 47: 38-44. PMID 7784897  0.647
1995 Plantinga LC, Verhaagen J, Edwards PM, Hali M, Brakkee JH, Gispen WH. Pharmacological evidence for the involvement of endogenous alpha-MSH-like peptides in peripheral nerve regeneration. Peptides. 16: 319-24. PMID 7784262 DOI: 10.1016/0196-9781(94)00179-0  0.653
1995 Hol EM, Gispen WH, Bär PR. ACTH-related peptides: receptors and signal transduction systems involved in their neurotrophic and neuroprotective actions. Peptides. 16: 979-93. PMID 7479345 DOI: 10.1016/0196-9781(95)00017-E  0.683
1995 Nacimiento W, Sappok T, Brook GA, Tóth L, Oestreicher AB, Gispen WH, Noth J, Kreutzberg GW. B-50 (GAP-43) in the rat spinal cord caudal to hemisection: lack of intraspinal sprouting by dorsal root axons. Neuroscience Letters. 194: 13-6. PMID 7478195 DOI: 10.1016/0304-3940(95)11707-4  0.511
1994 Verhaagen J, Hermens WT, Kaplitt MG, Pfaff DW, Gispen WH. B-50/GAP-43 expression via a defective herpes simplex virus vector results in persistent morphological changes in non-neuronal cells. Gene Therapy. 1: S81. PMID 8542427  0.614
1994 Duckers HJ, Verhaagen J, de Bruijn E, Gispen WH. Effective use of a neurotrophic ACTH4-9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis). An intervention study. Brain : a Journal of Neurology. 117: 365-74. PMID 8186962  0.651
1994 Joosten EA, Bär PR, Gispen WH. Corticospinal axons and mechanism of target innervation in rat lumbar spinal cord. Brain Research. Developmental Brain Research. 79: 122-7. PMID 8070056 DOI: 10.1016/0165-3806(94)90055-8  0.312
1994 Plantinga LC, Verhaagen J, Wong SL, Edwards PM, Bär PR, Gispen WH. The neurotrophic peptide Org 2766 does not influence the expression of the immediate early gene c-fos following sciatic nerve crush in the rat. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 12: 117-25. PMID 7942087 DOI: 10.1016/0736-5748(94)90004-3  0.652
1994 Gispen WH, Verhaagen J, Bär D. ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair. Progress in Brain Research. 100: 223-9. PMID 7938523 DOI: 10.1016/S0079-6123(08)60789-X  0.787
1994 Ulenkate HJ, Kaal EC, Gispen WH, Jennekens FG. Ciliary neurotrophic factor improves muscle fibre reinnervation after facial nerve crush in young rats. Acta Neuropathologica. 88: 558-64. PMID 7879603 DOI: 10.1007/Bf00296493  0.553
1994 Hol EM, Verhage M, Gispen WH, Bär PR. The role of calcium and cAMP in the mechanism of action of two melanocortins: alpha MSH and the ACTH4-9 analogue Org 2766. Brain Research. 662: 109-16. PMID 7859062 DOI: 10.1016/0006-8993(94)90802-8  0.669
1994 Verhaagen J, Hermens WT, Oestreicher AB, Gispen WH, Rabkin SD, Pfaff DW, Kaplitt MG. Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells. Brain Research. Molecular Brain Research. 26: 26-36. PMID 7854056 DOI: 10.1016/0169-328X(94)90070-1  0.638
1994 Gerritsen van der Hoop R, Hamers FP, Neijt JP, Veldman H, Gispen WH, Jennekens FG. Protection against cisplatin induced neurotoxicity by ORG 2766: histological and electrophysiological evidence. Journal of the Neurological Sciences. 126: 109-15. PMID 7853014 DOI: 10.1016/0022-510X(94)90259-3  0.579
1994 Hol EM, Mandys V, Sodaar P, Gispen WH, Bär PR. Protection by an ACTH4-9 analogue against the toxic effects of cisplatin and taxol on sensory neurons and glial cells in vitro. Journal of Neuroscience Research. 39: 178-85. PMID 7837287 DOI: 10.1002/jnr.490390208  0.666
1994 Hol EM, Gispen WH, Bär PR. Involvement of calcium and cAMP in the mechanism of action of two melanocortins: alpha MSH and an ACTH-(4-9) analogue. Annals of the New York Academy of Sciences. 739: 324-7. PMID 7832486 DOI: 10.1111/J.1749-6632.1994.Tb19836.X  0.646
1994 Plantinga LC, Schrama LH, Eggen BJ, Gispen WH, Verhaagen J, Lemke G. B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. Neuroreport. 5: 2465-8. PMID 7696581 DOI: 10.1097/00001756-199412000-00015  0.639
1994 Duckers H, van Dokkum R, Verhaagen J, Gispen W. A neurotrophic ACTH(4–9) analogue prevents the formation of central demyelinating lesions in CEAE and normalizes central conduction slowing Journal of Neuroimmunology. 54: 164. DOI: 10.1016/0165-5728(94)90333-6  0.599
1993 Ulenkate HJ, Verhaagen J, Plantinga LC, Mercken M, Veldman H, Jennekens FG, Gispen WH, Oestreicher AB. Upregulation of B-50/GAP-43 in Schwann cells at denervated motor endplates and in motoneurons after rat facial nerve crush. Restorative Neurology and Neuroscience. 6: 35-47. PMID 21551729 DOI: 10.3233/Rnn-1993-6104  0.747
1993 Plantinga LC, Verhaagen J, Gispen WH. The expression of B-50/GAP-43 in Schwann cells. Annals of the New York Academy of Sciences. 679: 412-7. PMID 8512206 DOI: 10.1111/j.1749-6632.1993.tb18331.x  0.62
1993 Plantinga LC, Verhaagen J, Edwards PM, Hol EM, Bär PR, Gispen WH. The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury. Brain Research. 602: 69-76. PMID 8448659 DOI: 10.1016/0006-8993(93)90243-G  0.782
1993 Nacimiento W, Mautes A, Töpper R, Oestreicher AB, Gispen WH, Nacimiento AC, Noth J, Kreutzberg GW. B-50 (GAP-43) in the spinal cord caudal to hemisection: indication for lack of intraspinal sprouting in dorsal root axons. Journal of Neuroscience Research. 35: 603-17. PMID 8411265 DOI: 10.1002/Jnr.490350604  0.481
1993 Hol EM, Hermens WT, Verhaagen J, Gispen WH, Bär PR. alpha MSH but not Org 2766 induces expression of c-fos in cultured rat spinal cord cells. Neuroreport. 4: 651-4. PMID 8394152  0.765
1993 Hol EM, van Essen EH, Gispen WH, Bär PR. alpha-MSH and ACTH4-9 analogue Org 2766 induce a cAMP increase in cultured rat spinal cord cells. Annals of the New York Academy of Sciences. 680: 533-5. PMID 8390185  0.648
1993 Duckers HJ, Verhaagen J, Gispen WH. A neurotrophic analogue of ACTH4-9 protects against experimental allergic neuritis. Annals of the New York Academy of Sciences. 680: 493-5. PMID 8390175  0.582
1993 Hamers FP, Pette C, Bravenboer B, Vecht CJ, Neijt JP, Gispen WH. Cisplatin-induced neuropathy in mature rats: effects of the melanocortin-derived peptide ORG 2766. Cancer Chemotherapy and Pharmacology. 32: 162-6. PMID 8387400 DOI: 10.1007/Bf00685621  0.394
1993 Bär PR, Renkema GH, Veraart CM, Hol EM, Gispen WH. Nimodipine protects cultured spinal cord neurones from depolarization-induced inhibition of neurite outgrowth. Cell Calcium. 14: 293-9. PMID 8370065 DOI: 10.1016/0143-4160(93)90050-G  0.649
1993 Nacimiento W, Töpper R, Fischer A, Möbius E, Oestreicher AB, Gispen WH, Nacimiento AC, Noth J, Kreutzberg GW. B-50 (GAP-43) in Onuf's nucleus of the adult cat. Brain Research. 613: 80-7. PMID 8348306 DOI: 10.1016/0006-8993(93)90457-X  0.482
1993 Nacimiento W, Töpper R, Fischer A, Oestreicher AB, Nacimiento AC, Gispen WH, Noth J, Kreutzberg GW. Immunocytochemistry of B-50 (GAP-43) in the spinal cord and in dorsal root ganglia of the adult cat. Journal of Neurocytology. 22: 413-24. PMID 8345365 DOI: 10.1007/BF01181562  0.5
1993 Verhaagen J, Zhang Y, Hamers FP, Gispen WH. Elevated expression of B-50 (GAP-43)-mRNA in a subpopulation of olfactory bulb mitral cells following axotomy. Journal of Neuroscience Research. 35: 162-9. PMID 8320748 DOI: 10.1002/jnr.490350206  0.669
1993 Ulenkate HJ, Verhagen MA, Gispen WH, Jennekens FG. The neurotrophic analogue of ACTH(4-9) reduces the perineuronal microglial reaction after rat facial nerve crush. Glia. 9: 219-26. PMID 8294151 DOI: 10.1002/Glia.440090307  0.628
1993 Hesselmans LF, Wieneke GH, Oey PL, Groenhout DM, van der Graaf Y, Gispen WH, Jennekens FG. Evaluation of electrophysiological and clinical tests in an exploratory trial of Org 2766 in motor neuron disease. Neuromuscular Disorders : Nmd. 3: 319-25. PMID 8268729 DOI: 10.1016/0960-8966(93)90025-F  0.491
1993 Florijn WJ, Holtmaat AJ, de Lang H, Spierenburg H, Gispen WH, Versteeg DH. Peptide-induced grooming behavior and caudate nucleus dopamine release. Brain Research. 625: 169-72. PMID 8242396 DOI: 10.1016/0006-8993(93)90151-C  0.732
1993 Duckers HJ, Verhaagen J, Gispen WH. The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis. Brain : a Journal of Neurology. 116: 1059-75. PMID 8221047  0.656
1993 Bär PR, Hol EM, Gispen WH. Trophic effects of melanocortins on neuronal cells in culture. Annals of the New York Academy of Sciences. 692: 284-6. PMID 8215033  0.626
1993 Versteeg DH, Florijn WJ, Holtmaat AJ, Gispen WH, De Wildt DJ. Synchronism of pressor response and grooming behavior in freely moving, conscious rats following intracerebroventricular administration of ACTH/MSH-like peptides. Brain Research. 631: 265-9. PMID 8131054 DOI: 10.1016/0006-8993(93)91544-3  0.738
1993 Hamers FP, Pette C, Neijt JP, Gispen WH. The ACTH-(4-9) analog, ORG 2766, prevents taxol-induced neuropathy in rats. European Journal of Pharmacology. 233: 177-8. PMID 8097161 DOI: 10.1016/0014-2999(93)90367-Q  0.361
1992 Ramakers GJ, Verhaagen J, Oestreicher AB, Margolis FL, van Bergen en Henegouwen PM, Gispen WH. Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: predominant presence in preterminal axons. Journal of Neurocytology. 21: 853-69. PMID 1469462 DOI: 10.1007/Bf01191683  0.64
1992 van der Neut R, Hol EM, Gispen WH, Bär PR. Stimulation by melanocortins of neurite outgrowth from spinal and sensory neurons in vitro. Peptides. 13: 1109-15. PMID 1337376 DOI: 10.1016/0196-9781(92)90015-U  0.68
1992 Plantinga LC, Verhaagen J, Edwards PM, Schrama LH, Burbach JP, Gispen WH. Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat. Brain Research. Molecular Brain Research. 16: 135-42. PMID 1334192 DOI: 10.1016/0169-328X(92)90203-N  0.659
1992 Gispen WH, Hamers FP, Vecht CJ, Jennekens FG, Neyt JP. ACTH/MSH like peptides in the treatment of cisplatin neuropathy. The Journal of Steroid Biochemistry and Molecular Biology. 43: 179-83. PMID 1326318  0.565
1990 Gispen WH, Boonstra J, De Graan PN, Jennekens FG, Oestreicher AB, Schotman P, Schrama LH, Verhaagen J, Margolis FL. B-50/GAP-43 in neuronal development and repair. Restorative Neurology and Neuroscience. 1: 237-44. PMID 21551562 DOI: 10.3233/Rnn-1990-13410  0.755
1990 van der Hoop RG, Vecht CJ, van der Burg ME, Elderson A, Boogerd W, Heimans JJ, Vries EP, van Houwelingen JC, Jennekens FG, Gispen WH. Prevention of cisplatin neurotoxicity with an ACTH(4-9) analogue in patients with ovarian cancer. The New England Journal of Medicine. 322: 89-94. PMID 2152972 DOI: 10.1056/Nejm199001113220204  0.531
1990 Verhaagen J, Oestreicher AB, Grillo M, Khew-Goodall YS, Gispen WH, Margolis FL. Neuroplasticity in the olfactory system: differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/GAP43 and the olfactory marker protein. Journal of Neuroscience Research. 26: 31-44. PMID 2141653 DOI: 10.1002/Jnr.490260105  0.637
1989 Hesselmans LF, Jennekens FG, van den Oord CJ, Oestreicher AB, Veldman H, Gispen WH. A light and electron microscopical study of B-50 (GAP-43) in human intramuscular nerve and neuromuscular junctions during development. Journal of the Neurological Sciences. 89: 301-11. PMID 2926454 DOI: 10.1016/0022-510X(89)90031-2  0.546
1989 Verhaagen J, Oestreicher AB, Gispen WH, Margolis FL. The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 683-91. PMID 2918383 DOI: 10.1523/Jneurosci.09-02-00683.1989  0.652
1989 Van der Zee CE, Nielander HB, Vos JP, Lopes da Silva S, Verhaagen J, Oestreicher AB, Schrama LH, Schotman P, Gispen WH. Expression of growth-associated protein B-50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3505-12. PMID 2552034 DOI: 10.1523/Jneurosci.09-10-03505.1989  0.697
1989 de Koning P, Verhaagen J, Sloot W, Jennekens FG, Gispen WH. Org.2766 stimulates collateral sprouting in the soleus muscle of the rat following partial denervation. Muscle & Nerve. 12: 353-9. PMID 2542784 DOI: 10.1002/Mus.880120503  0.712
1988 Verhaagen J, Oesteicher AB, Edwards PM, Veldman H, Jennekens FG, Gispen WH. Light- and electron-microscopical study of phosphoprotein B-50 following denervation and reinnervation of the rat soleus muscle. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1759-66. PMID 2966853 DOI: 10.1523/Jneurosci.08-05-01759.1988  0.752
1988 Gerritsen van der Hoop R, de Koning P, Boven E, Neijt JP, Jennekens FG, Gispen WH. Efficacy of the neuropeptide ORG.2766 in the prevention and treatment of cisplatin-induced neurotoxicity in rats. European Journal of Cancer & Clinical Oncology. 24: 637-42. PMID 2838292 DOI: 10.1016/0277-5379(88)90293-3  0.537
1988 Verhaagen J, Edwards PM, Gispen WH. Damaged rat peripheral nerves do not contain detectable amounts of alpha-MSH. Journal of Neuroscience Research. 19: 14-8. PMID 2830414 DOI: 10.1002/jnr.490190103  0.649
1988 Hoop RGvd, Neijt J, Jennekens F, Gispen W, Bär P, Wokke J, Jennekens F. Scientific meeting of the Amsterdamsche Neurologenvereeniging held in Amsterdam, 3rd December 1987 Clinical Neurology and Neurosurgery. 90: 183-184. DOI: 10.1016/S0303-8467(88)80047-7  0.583
1987 De Koning P, Neijt JP, Jennekens FG, Gispen WH. Evaluation of cis-diamminedichloroplatinum (II) (cisplatin) neurotoxicity in rats. Toxicology and Applied Pharmacology. 89: 81-7. PMID 3590191 DOI: 10.1016/0041-008X(87)90178-5  0.555
1987 de Koning P, Neijt JP, Jennekens FG, Gispen WH. Org.2766 protects from cisplatin-induced neurotoxicity in rats. Experimental Neurology. 97: 746-50. PMID 3040462 DOI: 10.1016/0014-4886(87)90132-4  0.562
1987 Gispen WH, De Koning P, Kuiters RR, Van der Zee CE, Verhaagen J. On the neurotrophic action of melanocortins. Progress in Brain Research. 72: 319-31. PMID 3039580 DOI: 10.1016/S0079-6123(08)60218-6  0.588
1987 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Early effect of an ACTH4-9 analog (Org.2766) on regenerative sprouting demonstrated by the use of neurofilament-binding antibodies isolated from a serum raised by alpha-MSH immunization. Brain Research. 404: 142-50. PMID 3032330 DOI: 10.1016/0006-8993(87)91365-5  0.723
1987 Verhaagen J, Edwards PM, Jennekens FG, Gispen WH. Pharmacological aspects of the influence of melanocortins on the formation of regenerative peripheral nerve sprouts. Peptides. 8: 581-4. PMID 2819831 DOI: 10.1016/0196-9781(87)90028-3  0.745
1987 Dekker A, Gispen WH, de Wied D. Axonal regeneration, growth factors and neuropeptides. Life Sciences. 41: 1667-78. PMID 2443782  0.56
1986 Verhaagen J, Edwards PM, Jennekens FG, Schotman P, Gispen WH. Alpha-melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush. Experimental Neurology. 92: 451-4. PMID 3956675 DOI: 10.1016/0014-4886(86)90098-1  0.738
1986 Gispen WH, Isaacson RL, Spruijt BM, de Wied D. Melanocortins, neural plasticity and aging. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 10: 415-26. PMID 3025925 DOI: 10.1016/0278-5846(86)90015-1  0.567
1986 Verhaagen J, van Hooff CO, Edwards PM, De Graan PN, Oestreicher AB, Schotman P, Jennekens FG, Gispen WH. The kinase C substrate protein B-50 and axonal regeneration. Brain Research Bulletin. 17: 737-41. PMID 2948616 DOI: 10.1016/0361-9230(86)90084-5  0.745
1986 Verhaagen J, Edwards PM, Schotman P, Jennekens FG, Gispen WH. Characterization of epitopes shared by alpha-melanocyte-stimulating hormone (alpha-MSH) and the 150-kD neurofilament protein (NF150): relationship to neurotrophic sequences. Journal of Neuroscience Research. 16: 589-600. PMID 2432275 DOI: 10.1002/jnr.490160402  0.703
1984 Edwards PM, Van der Zee CE, Verhaagen J, Schotman P, Jennekens FG, Gispen WH. Evidence that the neurotrophic actions of alpha-MSH may derive from its ability to mimick the actions of a peptide formed in degenerating nerve stumps. Journal of the Neurological Sciences. 64: 333-40. PMID 6432963 DOI: 10.1016/0022-510X(84)90181-3  0.739
1984 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Neurotrophic factors and regeneration in the peripheral nervous system. Psychoneuroendocrinology. 9: 199-215. PMID 6093175 DOI: 10.1016/0306-4530(84)90001-5  0.53
1983 Bijlsma WA, van Asselt E, Veldman H, Jennekens FG, Schotman P, Gispen WH. Ultrastructural study of effect of ACTH4-10 on nerve regeneration; axons become larger in number and smaller in diameter. Acta Neuropathologica. 62: 24-30. PMID 6318504 DOI: 10.1007/Bf00684916  0.565
1983 Bijlsma WA, Schotman P, Jennekens FG, Gispen WH. Regeneration and protein synthesis in the spinal cord: the influence of ACTH-like peptides on cell-free protein synthesis. Neuroscience Letters. 38: 297-302. PMID 6314188 DOI: 10.1016/0304-3940(83)90385-3  0.579
1983 Bijlsma WA, Schotman P, Jennekens FG, Gispen WH, De Wied D. The enhanced recovery of sensorimotor function in rats is related to the melanotropic moiety of ACTH/MSH neuropeptides. European Journal of Pharmacology. 92: 231-6. PMID 6313395 DOI: 10.1016/0014-2999(83)90291-1  0.727
1983 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Stimulation by ACTH4-10 of nerve fiber regeneration following sciatic nerve crush. Muscle & Nerve. 6: 104-12. PMID 6304506 DOI: 10.1002/Mus.880060205  0.547
1983 Drago F, Bohus B, Gispen WH, Scapagnini U, De Wied D. Prolactin-enhanced grooming behavior: interaction with ACTH. Brain Research. 263: 277-82. PMID 6301648 DOI: 10.1016/0006-8993(83)90320-7  0.591
1982 Zwiers H, Jolles J, Aloyo VJ, Oestreicher AB, Gispen WH. ACTH and synaptic membrane phosphorylation in rat brain. Progress in Brain Research. 56: 405-17. PMID 6298877 DOI: 10.1016/S0079-6123(08)63787-5  0.567
1982 Jolles J, van Dongen CJ, ten Haaf J, Gispen WH. Polyphosphoinositide metabolism in rat brain: effects of neuropeptides, neurotransmitters and cyclic nucleotides. Peptides. 3: 709-14. PMID 6129617  0.576
1981 Bijlsma WA, Jennekens FG, Schotman P, Gispen WH. Effects of corticotrophin (ACTH) on recovery of sensorimotor function in the rat: structure-activity study. European Journal of Pharmacology. 76: 73-9. PMID 6274673 DOI: 10.1016/0014-2999(81)90011-X  0.592
1981 Jolles J, Zwiers H, Dekker A, Wirtz KW, Gispen WH. Corticotropin-(1--24)-tetracosapeptide affects protein phosphorylation and polyphosphoinositide metabolism in rat brain. The Biochemical Journal. 194: 283-91. PMID 6272727 DOI: 10.1042/Bj1940283  0.56
1981 Jolles J, Schrama LH, Gispen WH. Calcium-dependent turnover of brain polyphosphoinositides in vitro after prelabelling in vivo. Biochimica Et Biophysica Acta. 666: 90-8. PMID 6271236  0.577
1981 Jolles J, Bär PR, Gispen WH. Modulation of brain polyphosphoinositide metabolism by ACTH and beta-endorphin: structure-activity studies. Brain Research. 224: 315-26. PMID 6269709  0.569
1981 van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GA, van Wimersma Greidanus TB, Witter A, de Wied D. Gamma-melanotropin and brain function. Ciba Foundation Symposium. 81: 263-76. PMID 6268381  0.71
1981 van Ree JM, Bohus B, Csontos KM, Gispen WH, Greven HM, Nijkamp FP, Opmeer FA, de Rotte GA, van Wimersma Greidanus TB, Witter A, de Wied D. Behavioral profile of gamma-MSH: relationship with ACTH and beta-endorphin action. Life Sciences. 28: 2875-8. PMID 6267399 DOI: 10.1016/0024-3205(81)90104-1  0.709
1980 Rees HD, Verhoef J, Witter A, Gispen WH, de Wied D. Autoradiographic studies with a behaviorally potent 3H-ACTH4--9 analog in the brain after intraventricular injection in rats. Brain Research Bulletin. 5: 509-14. PMID 6253028  0.604
1980 Jolles J, Zwiers H, van Dongen CJ, Schotman P, Wirtz KW, Gispen WH. Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation. Nature. 286: 623-5. PMID 6250080 DOI: 10.1038/286623A0  0.559
1980 Gispen WH, Ormond D, ten Haaf J, De Wied D. Modulation of ACTH-induced grooming by [Des-Tyr1]-gamma-endorphin and haloperidol. European Journal of Pharmacology. 63: 203-7. PMID 6247168  0.573
1980 Verhoef J, Loeber JG, Burbach JP, Gispen WH, Witter A, de Wied D. Alpha-endorphin, gamma-endorphin and their des-tyrosine fragments in rat pituitary and brain tissue. Life Sciences. 26: 851-9. PMID 6154859 DOI: 10.1016/0024-3205(80)90347-1  0.579
1980 Gispen WH, de Wied D. ACTH as neuromodulator: behavioral and neurochemical aspects. Progress in Clinical and Biological Research. 39: 251-63. PMID 6105672  0.523
1979 Wiegant VM, Jolles J, Colbern DL, Zimmermann E, Gispen WH. Intracerebroventricular ACTH activates the pituitary-adrenal system:dissociation from a behavioral response. Life Sciences. 25: 1791-6. PMID 231165  0.539
1979 Jolles J, Wirtz KW, Schotman P, Gispen WH. Pituitary hormones influence polyphosphoinositide metabolism in rat brain. Febs Letters. 105: 110-4. PMID 226403 DOI: 10.1016/0014-5793(79)80897-2  0.58
1979 Jolles J, Rompa-Barendregt J, Gispen WH. ACTH-induced excessive grooming in the rat: the influence of environmental and motivational factors. Hormones and Behavior. 12: 60-72. PMID 225257  0.571
1979 Jolles J, Rompa-Barendregt J, Gispen W. Novelty and grooming behavior in the rat Behavioral and Neural Biology. 25: 563-572. DOI: 10.1016/S0163-1047(79)90362-5  0.564
1978 Jolles J, Wiegant VM, Gispen WH. Reduced behavioral effectiveness of ACTH(1-24) after a second administration: interaction with opiates. Neuroscience Letters. 9: 261-6. PMID 19605229  0.56
1978 Reith ME, Schotman P, Gispen WH. Measurements of in vivo rates of protein synthesis in brain, spinal cord, heart and liver of young versus adult rats, intact versus hypophysectomized rats. Journal of Neurochemistry. 30: 587-94. PMID 681932 DOI: 10.1111/j.1471-4159.1978.tb07812.x  0.536
1978 Wiegant VM, Colbern D, Van Wimersma Greidanus TB, Gispen WH. Differential behavioral effects of ACTH 4-10 and [D-Phe7]ACTH 4-10 Brain Research Bulletin. 3: 167-170. PMID 206319 DOI: 10.1016/0361-9230(78)90042-4  0.579
1978 SCHOTMAN P, GIPON L, JENNEKENS FG, GISPEN WH. POLYNEUROPATHIES AND CNS PROTEIN METABOLISM Journal of Neuropathology and Experimental Neurology. 37: 820-837. DOI: 10.1097/00005072-197811000-00008  0.523
1977 Schotman P, Reith ME, Gispen WH. Effects of stressful procedures as ether anesthesia and intracranial injections on amino acid incorporation into brain protein. Brain Research Bulletin. 2: 83-7. PMID 880489 DOI: 10.1016/0361-9230(77)90002-8  0.528
1977 Gispen WH, Reith ME, Schotman P, Wiegant VM, Zwiers H, de Wied D. CNS and ACTH-like peptides: neurochemical response and interaction with opiates. Advances in Biochemical Psychopharmacology. 17: 61-80. PMID 200081  0.686
1977 Wiegant VM, Gispen WH, Terenius L, de Wied D. ACTH-like peptides and morphine: interaction at the level of the CNS. Psychoneuroendocrinology. 2: 63-70. PMID 198834  0.564
1977 Gispen WH, van Ree JM, de Wied D. Lipotropin and the central nervous system. International Review of Neurobiology. 20: 209-50. PMID 22510  0.558
1977 Reith M, Schotman P, Gispen W, de Wied D. Pituitary peptides as modulators of neural functioning Trends in Biochemical Sciences. 2: 56-58. DOI: 10.1016/0968-0004(77)90095-0  0.555
1976 De Wied D, Gispen WH. Impaired development of tolerance to morphine analgesia in rats with hereditary diabetes insipidus. Psychopharmacologia. 46: 27-9. PMID 1257364 DOI: 10.1007/BF00421545  0.573
1976 de Wied D, van Wimersma Greidanus TB, Bohus B, Urban I, Gispen WH. Vasopressin and memory consolidation. Progress in Brain Research. 45: 181-94. PMID 1013337 DOI: 10.1016/S0079-6123(08)60990-5  0.654
1976 Gispen WH, Wiegant VM, Bradbury AF, Hulme EC, Smyth DG, Snell CR, de Wied D. Induction of excessive grooming in the rat by fragments of lipotropin. Nature. 264: 794-5. PMID 189197 DOI: 10.1038/264794A0  0.614
1976 Gispen WH, Buitelaar J, Wiegant VM, Terenius L, De Wied D. Interaction between ACTH fragments, brain opiate receptors and morphine-induced analgesia. European Journal of Pharmacology. 39: 393-7. PMID 185067  0.584
1975 Reith ME, Schotman P, Gispen WH. The neurotropic action of ACTH: effects of ACTH-like peptides on the incorporation of leucine into protein of brain stem slices from hypophysectomized rats. Neuroscience Letters. 1: 55-9. PMID 19604752 DOI: 10.1016/0304-3940(75)90012-9  0.569
1975 Gispen WH, Krivoy WA, de Wied D, Zimmermann E. Effect of rifampicin on development of tolerance to analgesic actions. Life Sciences. 17: 247-51. PMID 1160497  0.527
1975 Terenius L, Gispen WH, De Wied D. ACTH-like peptides and opiate receptors in the rat brain: structure-activity studies. European Journal of Pharmacology. 33: 395-9. PMID 241656 DOI: 10.1016/0014-2999(75)90185-5  0.592
1975 Reith ME, Schotman P, Gispen WH. Effects of behaviorally active ACTH analogs on brain protein metabolism. Progress in Brain Research. 42: 195-200. PMID 172963 DOI: 10.1016/S0079-6123(08)63660-2  0.51
1975 Gispen WH, Wiegant VM, Greven HM, de Wied D. The induction of excessive grooming in the rat by intraventricular application of peptides derived from ACTH: structure-activity studies. Life Sciences. 17: 645-52. PMID 171535  0.588
1975 Gispen WH, Van Wimersma Greidanus TB, Waters-Ezrin C, Zimmermann E, Krivoy WA, De Wied D. Influence of peptides on reduced response of rats to electric footshock after acute administration of morphine. European Journal of Pharmacology. 33: 99-105. PMID 170120 DOI: 10.1016/0014-2999(75)90143-0  0.711
1974 Reith ME, Schotman P, Gispen WH. Hypophysectomy, ACTH1-10 and in vitro protein synthesis in rat brain stem slices. Brain Research. 81: 571-5. PMID 4373137 DOI: 10.1016/0006-8993(74)90855-5  0.541
1973 Bohus B, Gispen WH, De Wied D. Effect of lysine vasopressin and ACTH 4-10 on conditioned avoidance behavior of hypophysectomized rats. Neuroendocrinology. 11: 137-43. PMID 4349360 DOI: 10.1159/000122126  0.571
1972 Schotman P, Gispen WH, Jansz HS, De Wied D. Effects of ACTH analogues on macromolecule metabolism in the brain stem of hypophysectomized rats. Brain Research. 46: 349-62. PMID 4344078 DOI: 10.1016/0006-8993(72)90025-X  0.699
1972 Versteeg DH, Gispen WH, Schotmann P, Witter A, de Wied D. Hypophysectomy and rat brain metabolism: effects of synthetic ACTH analogs. Advances in Biochemical Psychopharmacology. 6: 219-39. PMID 4341334  0.578
1971 Gispen WH, de Wied D, Schotman P, Jansz HS. Brain stem polysomes and avoidance performance of hypophysectomized rats subjected to peptide treatment. Brain Research. 31: 341-51. PMID 4328057 DOI: 10.1016/0006-8993(71)90187-9  0.707
1970 Gispen WH, de Wied D, Schotman P, Jansz HS. On the relationship between the deficient performance of hypophysectomized rats in shuttle-box conditioning and the RNA metabolism in their brain stem. Brain Research. 24: 551. PMID 5494550  0.686
1970 Gispen WH, de Wied D, Schotman P, Jansz HS. Effects of hypophysectomy on RNA metabolism in rat brain stem. Journal of Neurochemistry. 17: 751-61. PMID 4987663 DOI: 10.1111/J.1471-4159.1970.Tb03345.X  0.682
1970 Gispen WH, v Wimersma Greidanus TB, de Wied D. Effects of hypophysectomy and ACTH 1-10 on responsiveness to electric shock in rats. Physiology & Behavior. 5: 143-6. PMID 4337772  0.564
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