Year |
Citation |
Score |
2019 |
McGary EC, Weber K, Mills L, Doucet M, Lewis V, Lev DC, Fidler IJ, Bar-Eli M. Editor's Note: Inhibition of Platelet-derived Growth Factor-mediated Proliferation of Osteosarcoma Cells by the Novel Tyrosine Kinase Inhibitor STI571. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 25: 3196. PMID 31092620 DOI: 10.1158/1078-0432.Ccr-19-1101 |
0.415 |
|
2016 |
Fidler IJ. Commentary on "Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis". Cancer Research. 76: 3441-2. PMID 27306869 DOI: 10.1158/0008-5472.Can-16-1330 |
0.359 |
|
2016 |
Lee HJ, Hanibuchi M, Kim SJ, Yu H, Kim MS, He J, Langley RR, Lehembre F, Regenass U, Fidler IJ. Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. Neuro-Oncology. 18: 486-496. PMID 26995790 DOI: 10.1093/Neuonc/Now037 |
0.373 |
|
2016 |
Lee HJ, Yu HK, Kim SW, Choi SI, He J, Fidler IJ, Kim SJ. Abstract 737: Transcriptome of glioma growing in the brain is simulated by tumor cells cultured under low oxygen pressure Cancer Research. 76: 737-737. DOI: 10.1158/1538-7445.Am2016-737 |
0.396 |
|
2016 |
Yu HK, Lee HJ, Zhang F, Wu Q, Fidler IJ, Kim SJ. Abstract 2943: Hypoxia induced resistance to chemotherapy is regulated by the endothelin receptor axis Cancer Research. 76: 2943-2943. DOI: 10.1158/1538-7445.Am2016-2943 |
0.457 |
|
2015 |
Fidler IJ, Kripke ML. The challenge of targeting metastasis. Cancer Metastasis Reviews. 34: 635-41. PMID 26328524 DOI: 10.1007/S10555-015-9586-9 |
0.453 |
|
2015 |
Fidler IJ. The Biology of Brain Metastasis: Challenges for Therapy. Cancer Journal (Sudbury, Mass.). 21: 284-93. PMID 26222080 DOI: 10.1097/Ppo.0000000000000126 |
0.454 |
|
2015 |
Kim SJ, Lee HJ, Kim SW, Choi HJ, He J, Wu Q, Aldape KD, Weinberg JS, Yung WK, Conrad CA, Langley RR, Lehembre F, Regenass U, Fidler IJ. Macitentan, a dual endothelin receptor antagonist, in combination with temozolomide leads to glioblastoma regression and long-term survival in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26106074 DOI: 10.1158/1078-0432.Ccr-14-3195 |
0.364 |
|
2015 |
Kim SW, Kim SJ, Langley RR, Fidler IJ. Modulation of the cancer cell transcriptome by culture media formulations and cell density. International Journal of Oncology. 46: 2067-75. PMID 25776572 DOI: 10.3892/Ijo.2015.2930 |
0.383 |
|
2015 |
Shoshan E, Mobley AK, Braeuer RR, Kamiya T, Huang L, Vasquez ME, Salameh A, Lee HJ, Kim SJ, Ivan C, Velazquez-Torres G, Nip KM, Zhu K, Brooks D, Jones SJ, ... ... Fidler IJ, et al. Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nature Cell Biology. 17: 311-21. PMID 25686251 DOI: 10.1038/Ncb3110 |
0.315 |
|
2015 |
Kim MS, Choi HJ, Lee H, He J, We Q, Langley RR, Kim S, Fidler IJ. Abstract 5463: Role of the endothelin axis in astrocyte and endothelial cell mediated chemoprotection of cancer cells Cancer Research. 75: 5463-5463. DOI: 10.1158/1538-7445.Am2015-5463 |
0.426 |
|
2015 |
Lee HJ, Kim SJ, Yu HK, Kim SW, Wu Q, He J, Fidler IJ. Abstract 5154: Diagnostic serum markers for metastatic brain tumors identified by cross-species hybridization of microarrays in animal models Cancer Research. 75: 5154-5154. DOI: 10.1158/1538-7445.Am2015-5154 |
0.413 |
|
2015 |
Dai Y, Zhu L, Cho E, Hagiwara A, Faller D, Kim S, Fidler IJ, Amaro M. Abstract 2056: SIRT1 silencing suppresses prostate cancer growth and metastasis in an orthotopic prostate cancer mouse model Cancer Research. 75: 2056-2056. DOI: 10.1158/1538-7445.Am2015-2056 |
0.395 |
|
2014 |
Hanibuchi M, Kim SJ, Fidler IJ, Nishioka Y. The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives. The Journal of Medical Investigation : Jmi. 61: 241-53. PMID 25264041 DOI: 10.2152/Jmi.61.241 |
0.326 |
|
2014 |
Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, ... ... Fidler IJ, et al. Hematogenous metastasis of ovarian cancer: rethinking mode of spread. Cancer Cell. 26: 77-91. PMID 25026212 DOI: 10.1016/J.Ccr.2014.05.002 |
0.382 |
|
2014 |
Kim SW, Choi HJ, Lee HJ, He J, Wu Q, Langley RR, Fidler IJ, Kim SJ. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells. Neuro-Oncology. 16: 1585-98. PMID 25008093 DOI: 10.1093/Neuonc/Nou128 |
0.426 |
|
2014 |
Shoshan E, Mobley A, Braeuer R, Kamiya T, Huang L, Vasquez M, Jeong LH, kim SJ, Calin G, Sood A, Markel G, Fidler I, Bar-Eli M. Abstract 4969: Hypo adenosine-to-inosine editing of microRNA-455 promotes melanoma metastasis Cancer Research. 74: 4969-4969. DOI: 10.1158/1538-7445.Am2014-4969 |
0.338 |
|
2014 |
Kim SW, Kim SJ, Lee H, He J, Wu Q, Lawson EJ, Fidler IJ. Abstract 4878: Modification of gene expression in tumor cells by the culture microenvironment Cancer Research. 74: 4878-4878. DOI: 10.1158/1538-7445.Am2014-4878 |
0.391 |
|
2014 |
Lee HJ, Kim SJ, Kim SW, He J, Wu Q, Lawson EJ, Lehembre F, Regenass U, Fidler IJ. Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel Cancer Research. 74: 3779-3779. DOI: 10.1158/1538-7445.Am2014-3779 |
0.458 |
|
2013 |
Langley RR, Fidler IJ. The biology of brain metastasis. Clinical Chemistry. 59: 180-9. PMID 23115057 DOI: 10.1373/Clinchem.2012.193342 |
0.413 |
|
2013 |
Yokoi K, Godin B, Oborn CJ, Alexander JF, Liu X, Fidler IJ, Ferrari M. Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers. Cancer Letters. 334: 319-27. PMID 23000514 DOI: 10.1016/J.Canlet.2012.09.001 |
0.456 |
|
2013 |
Kim SJ, Kim SW, Choi HJ, Lee HJ, Lehembre F, He J, Regenass U, Conrad CA, Yung WK, Fidler IJ. Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide. Cancer Research. 73: 5481-5481. DOI: 10.1158/1538-7445.Am2013-5481 |
0.424 |
|
2013 |
Kim SW, Kim SJ, Choi HJ, Lee H, He J, Wu Q, Lawson EJ, Fidler IJ. Abstract 4951: The role of endothelin axis signaling pathway in astrocyte mediated chemoprotection of tumor cells. Cancer Research. 73: 4951-4951. DOI: 10.1158/1538-7445.Am2013-4951 |
0.478 |
|
2013 |
Pradeep S, Wook K, Nishimura M, Raghavan P, Pecot C, Lopez G, Fidler I, Sood A. Abstract 408: Hematogenous metastasis in ovarian cancer: Importance of the ErbB3/NRG axis. Cancer Research. 73: 408-408. DOI: 10.1158/1538-7445.Am2013-408 |
0.47 |
|
2012 |
Fidler IJ. Biological heterogeneity of cancer: implication to therapy. Human Vaccines & Immunotherapeutics. 8: 1141-2. PMID 22854675 DOI: 10.4161/Hv.19643 |
0.46 |
|
2012 |
Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, Fan D, Strickner P, Lehembre F, Regenass U, Fidler IJ. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist. Translational Oncology. 5: 39-47. PMID 22348175 DOI: 10.1593/Tlo.11286 |
0.463 |
|
2012 |
Fujimaki T, Ellis L, Bucana C, Radinsky R, Price J, Fidler I. Simultaneous radiolabel, genetic tagging and proliferation assays to study the organ distribution and fate of metastatic cells. International Journal of Oncology. 2: 895-901. PMID 21573644 DOI: 10.3892/ijo.2.6.895 |
0.379 |
|
2012 |
Wilmanns C, Fan D, Obrian C, Radinsky R, Bucana C, Tsan R, Fidler I. Modulation of Doxorubicin sensitivity and level of p-glycoprotein expression in human colon-carcinoma cells by ectopic and orthotopic environments in nude-mice. International Journal of Oncology. 3: 413-22. PMID 21573380 DOI: 10.3892/Ijo.3.3.413 |
0.356 |
|
2012 |
Berry K, Siegal G, Boyd J, Singh R, Fidler I. Development of a metastatic model for human endometrial carcinoma using orthotopic implantation in nude-mice. International Journal of Oncology. 4: 1163-71. PMID 21567033 DOI: 10.3892/ijo.4.6.1163 |
0.379 |
|
2012 |
Singh R, Bucana C, Llansa N, Sanchez R, Fidler I. Cell density-dependent modulation of basic fibroblast growth factor expression by human interferon-beta. International Journal of Oncology. 8: 649-56. PMID 21544408 DOI: 10.3892/Ijo.8.4.649 |
0.356 |
|
2012 |
Fan D, Beltran P, Wang Y, Bucana C, Yoon S, Deguzman A, Fidler I. Cell density-dependent regulation of mdr-1 gene expression in murine colon cancer cells. International Journal of Oncology. 9: 865-78. PMID 21541589 DOI: 10.3892/Ijo.9.5.865 |
0.431 |
|
2012 |
Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, Fan D, Strickner P, Lehembre F, Regenass U, Fidler IJ. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist Translational Oncology. 5: 39-47. DOI: 10.1593/tlo.11286 |
0.357 |
|
2012 |
Hanibuchi M, Kim S, Otsuka K, Tabata S, Kuramoto T, Goto H, Nishioka Y, Fidler IJ. Eradication of experimental brain metastases of human non-small cell lung cancer by macitentan, a dual antagonist of the endothelin A and B receptor, combined with paclitaxel. Journal of Clinical Oncology. 30: 92-92. DOI: 10.1200/Jco.2012.30.30_Suppl.92 |
0.456 |
|
2012 |
Park ES, Kim S, Kim SW, Yoon S, Leem S, Kim S, Kim SM, Park Y, Cheong J, Woo HG, Mills GB, Fidler IJ, Lee J. Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis Cancer Research. 72: 4283-4283. DOI: 10.1158/1538-7445.Am2012-4283 |
0.451 |
|
2012 |
Yokoi K, Ven AVd, Alexander JF, Bai L, Liu X, Fidler IJ, Ferrari M, Godin B. Abstract 2453: Overcoming transport barriers in liver metastasis with multi-stage nanovectors (MSV) Cancer Research. 72: 2453-2453. DOI: 10.1158/1538-7445.Am2012-2453 |
0.41 |
|
2011 |
Park ES, Kim SJ, Kim SW, Yoon SL, Leem SH, Kim SB, Kim SM, Park YY, Cheong JH, Woo HG, Mills GB, Fidler IJ, Lee JS. Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 17456-61. PMID 21987811 DOI: 10.1073/Pnas.1114210108 |
0.458 |
|
2011 |
Guo L, Fan D, Zhang F, Price JE, Lee JS, Marchetti D, Fidler IJ, Langley RR. Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar. The American Journal of Pathology. 178: 2357-66. PMID 21514446 DOI: 10.1016/J.Ajpath.2011.01.047 |
0.446 |
|
2011 |
Yokoi K, Hawke D, Oborn CJ, Jang JY, Nishioka Y, Fan D, Kim SW, Kim SJ, Fidler IJ. Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer. Translational Oncology. 4: 83-91. PMID 21461171 DOI: 10.1593/Tlo.10202 |
0.384 |
|
2011 |
Kim SJ, Kim JS, Kim SW, Brantley E, Yun SJ, He J, Maya M, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer Neoplasia. 13: 167-179. PMID 21403842 DOI: 10.1593/Neo.10806 |
0.482 |
|
2011 |
Kim SJ, Kim JS, Park ES, Lee JS, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung MC, Fidler IJ. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia (New York, N.Y.). 13: 286-98. PMID 21390191 DOI: 10.1593/Neo.11112 |
0.789 |
|
2011 |
Langley RR, Fidler IJ. The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs. International Journal of Cancer. 128: 2527-35. PMID 21365651 DOI: 10.1002/Ijc.26031 |
0.408 |
|
2011 |
Weihua Z, Lin Q, Ramoth AJ, Fan D, Fidler IJ. Formation of solid tumors by a single multinucleated cancer cell. Cancer. 117: 4092-9. PMID 21365635 DOI: 10.1002/Cncr.26021 |
0.776 |
|
2011 |
Kim SW, Kim JS, Papadopoulos J, Choi HJ, He J, Maya M, Langley RR, Fan D, Fidler IJ, Kim SJ. Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse. International Immunopharmacology. 11: 862-72. PMID 21251905 DOI: 10.1016/J.Intimp.2011.01.004 |
0.427 |
|
2011 |
Fidler IJ. The role of the organ microenvironment in brain metastasis. Seminars in Cancer Biology. 21: 107-12. PMID 21167939 DOI: 10.1016/J.Semcancer.2010.12.009 |
0.482 |
|
2011 |
Fidler IJ. The biology of cancer metastasis. Seminars in Cancer Biology. 21: 71. PMID 21145967 DOI: 10.1016/J.Semcancer.2010.12.004 |
0.338 |
|
2011 |
Kim SJ, Kim JS, Kim SW, Brantley EC, Yun SJ, He J, Marva MK, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer Cancer Research. 71: 601-601. DOI: 10.1158/1538-7445.Am2011-601 |
0.482 |
|
2011 |
Yokoi K, Godin B, Alexander JF, Hu T, Liu X, Fidler I, Ferrari M. Abstract 379: Target delivery of multistage nanovectors to tumor-associated macrophages and endothelial cells in orthotopic model of human pancreatic cancer Cancer Research. 71: 379-379. DOI: 10.1158/1538-7445.Am2011-379 |
0.488 |
|
2011 |
Yokoi K, Xuewu L, Alexander J, Fidler I, Mauro F, Biana G. P4-17-10: Insights into Mechanisms Involved in the Accumulation of Nanovectors within the Breast Cancer Brain Metastasis. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-17-10 |
0.387 |
|
2010 |
Brantley EC, Guo L, Zhang C, Lin Q, Yokoi K, Langley RR, Kruzel E, Maya M, Kim SW, Kim SJ, Fan D, Fidler IJ. Nitric oxide-mediated tumoricidal activity of murine microglial cells. Translational Oncology. 3: 380-8. PMID 21151477 DOI: 10.1593/Tlo.10208 |
0.772 |
|
2010 |
Lin Q, Balasubramanian K, Fan D, Kim SJ, Guo L, Wang H, Bar-Eli M, Aldape KD, Fidler IJ. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. Neoplasia (New York, N.Y.). 12: 748-54. PMID 20824051 DOI: 10.1593/Neo.10602 |
0.767 |
|
2010 |
Ellis LM, Fidler IJ. Finding the tumor copycat. Therapy fails, patients don't. Nature Medicine. 16: 974-5. PMID 20823880 DOI: 10.1038/Nm0910-974 |
0.391 |
|
2010 |
Fidler IJ, Balasubramanian K, Lin Q, Kim SW, Kim SJ. The brain microenvironment and cancer metastasis. Molecules and Cells. 30: 93-8. PMID 20799011 DOI: 10.1007/S10059-010-0133-9 |
0.765 |
|
2010 |
Talmadge JE, Fidler IJ. AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Research. 70: 5649-69. PMID 20610625 DOI: 10.1158/0008-5472.Can-10-1040 |
0.403 |
|
2010 |
Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, ... ... Fidler IJ, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling. 3: ra9. PMID 20145209 DOI: 10.1126/Scisignal.2000590 |
0.381 |
|
2010 |
Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia (New York, N.Y.). 12: 173-82. PMID 20126475 DOI: 10.1593/Neo.91604 |
0.682 |
|
2010 |
Kim SJ, Kim J, Park ES, Lee J, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung M, Fidler IJ. Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy Cancer Research. 70: 3428-3428. DOI: 10.1158/1538-7445.Am10-3428 |
0.498 |
|
2009 |
Langley RR, Fan D, Guo L, Zhang C, Lin Q, Brantley EC, McCarty JH, Fidler IJ. Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis. International Journal of Oncology. 35: 665-72. PMID 19724901 DOI: 10.3892/Ijo_00000378 |
0.758 |
|
2009 |
Kim SJ, Kim JS, Papadopoulos J, Wook Kim S, Maya M, Zhang F, He J, Fan D, Langley R, Fidler IJ. Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis. The American Journal of Pathology. 174: 1972-80. PMID 19349357 DOI: 10.2353/Ajpath.2009.080819 |
0.389 |
|
2009 |
Zhang C, Zhang F, Tsan R, Fidler IJ. Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain. Cancer Research. 69: 828-35. PMID 19141644 DOI: 10.1158/0008-5472.Can-08-2588 |
0.387 |
|
2009 |
Mathew P, Pisters LL, Wood CG, Papadopoulos JN, Williams DL, Thall PF, Wen S, Horne E, Oborn CJ, Langley R, Fidler IJ, Pettaway CA. Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer. The Journal of Urology. 181: 81-7; discussion 87. PMID 19012911 DOI: 10.1016/J.Juro.2008.09.006 |
0.304 |
|
2008 |
Mathew P, Thall PF, Wen S, Bucana C, Jones D, Horne E, Oh WK, Morris MJ, Lee YC, Logothetis CJ, Lin SH, Fidler IJ. Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer British Journal of Cancer. 99: 1426-1432. PMID 18841158 DOI: 10.1038/Sj.Bjc.6604706 |
0.318 |
|
2008 |
Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200 |
0.349 |
|
2008 |
Sasaki T, Nakamura T, Rebhun RB, Cheng H, Hale KS, Tsan RZ, Fidler IJ, Langley RR. Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model. The American Journal of Pathology. 173: 205-16. PMID 18583324 DOI: 10.2353/Ajpath.2008.071147 |
0.701 |
|
2008 |
Kuwai T, Nakamura T, Sasaki T, Kim SJ, Fan D, Villares GJ, Zigler M, Wang H, Bar-Eli M, Kerbel RS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. Neoplasia (New York, N.Y.). 10: 489-500. PMID 18472966 DOI: 10.1593/Neo.08200 |
0.456 |
|
2008 |
Weihua Z, Tsan R, Huang WC, Wu Q, Chiu CH, Fidler IJ, Hung MC. Survival of cancer cells is maintained by EGFR independent of its kinase activity. Cancer Cell. 13: 385-93. PMID 18455122 DOI: 10.1016/J.Ccr.2008.03.015 |
0.393 |
|
2008 |
Kuwai T, Nakamura T, Sasaki T, Kitadai Y, Kim JS, Langley RR, Fan D, Wang X, Do KA, Kim SJ, Fidler IJ. Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy. Clinical & Experimental Metastasis. 25: 477-89. PMID 18324358 DOI: 10.1007/S10585-008-9153-7 |
0.517 |
|
2008 |
Rebhun RB, Lazar AJ, Fidler IJ, Gershenwald JE. Impact of sentinel lymphadenectomy on survival in a murine model of melanoma. Clinical & Experimental Metastasis. 25: 191-9. PMID 18264782 DOI: 10.1007/S10585-008-9141-Y |
0.642 |
|
2008 |
Kuwai T, Nakamura T, Kim SJ, Sasaki T, Kitadai Y, Langley RR, Fan D, Hamilton SR, Fidler IJ. Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. The American Journal of Pathology. 172: 358-66. PMID 18202197 DOI: 10.2353/Ajpath.2008.070625 |
0.465 |
|
2008 |
Kitadai Y, Kodama M, Tanaka M, Sasaki T, Kuwai T, Nakamura T, Fidler I. Inhibition of reactive stroma by platelet derived growth factor receptor (PDGF-R) tyrosine kinase inhibitor reduces growth and lymph node metastasis of human colon carcinoma European Journal of Cancer Supplements. 6: 68. DOI: 10.1016/S1359-6349(08)71436-8 |
0.33 |
|
2008 |
Yazici S, Busby E, Kim SJ, Fidler IJ. IN VIVO IMAGING OF LUCIFERASE-LABELED HUMAN PROSTATE CANCER CELLS, PC-3MM2, IN ORTHOTOPIC NUDE MOUSE MODELS Journal of Urology. 179: 425-425. DOI: 10.1016/S0022-5347(08)61246-X |
0.335 |
|
2007 |
Sasaki T, Kitadai Y, Nakamura T, Kim JS, Tsan RZ, Kuwai T, Langley RR, Fan D, Kim SJ, Fidler IJ. Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice. Neoplasia (New York, N.Y.). 9: 1066-77. PMID 18084614 DOI: 10.1593/Neo.07667 |
0.482 |
|
2007 |
Nakamura T, Kuwai T, Kim JS, Fan D, Kim SJ, Fidler IJ. Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice. Neoplasia (New York, N.Y.). 9: 979-86. PMID 18030366 DOI: 10.1593/Neo.07742 |
0.375 |
|
2007 |
Wu W, O'Reilly MS, Langley RR, Tsan RZ, Baker CH, Bekele N, Tang XM, Onn A, Fidler IJ, Herbst RS. Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Molecular Cancer Therapeutics. 6: 2652-63. PMID 17913856 DOI: 10.1158/1535-7163.Mct-06-0759 |
0.47 |
|
2007 |
Mathew P, Thall PF, Bucana CD, Oh WK, Morris MJ, Jones DM, Johnson MM, Wen S, Pagliaro LC, Tannir NM, Tu SM, Meluch AA, Smith L, Cohen L, Kim SJ, ... ... Fidler IJ, et al. Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5816-24. PMID 17908974 DOI: 10.1158/1078-0432.Ccr-07-1269 |
0.318 |
|
2007 |
Nakamura T, Kuwai T, Kitadai Y, Sasaki T, Fan D, Coombes KR, Kim SJ, Fidler IJ. Zonal heterogeneity for gene expression in human pancreatic carcinoma. Cancer Research. 67: 7597-604. PMID 17699763 DOI: 10.1158/0008-5472.Can-07-0874 |
0.399 |
|
2007 |
Langley RR, Fidler IJ. Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocrine Reviews. 28: 297-321. PMID 17409287 DOI: 10.1210/Er.2006-0027 |
0.494 |
|
2007 |
Talmadge JE, Singh RK, Fidler IJ, Raz A. Murine models to evaluate novel and conventional therapeutic strategies for cancer. The American Journal of Pathology. 170: 793-804. PMID 17322365 DOI: 10.2353/Ajpath.2007.060929 |
0.374 |
|
2007 |
Wu W, Onn A, Isobe T, Itasaka S, Langley RR, Shitani T, Shibuya K, Komaki R, Ryan AJ, Fidler IJ, Herbst RS, O'Reilly MS. Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade. Molecular Cancer Therapeutics. 6: 471-83. PMID 17308046 DOI: 10.1158/1535-7163.Mct-06-0416 |
0.411 |
|
2007 |
Nakamura T, Fidler IJ, Coombes KR. Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment. Cancer Research. 67: 139-48. PMID 17210693 DOI: 10.1158/0008-5472.Can-06-2563 |
0.399 |
|
2007 |
Fidler IJ, Kim SJ, Langley RR. The role of the organ microenvironment in the biology and therapy of cancer metastasis. Journal of Cellular Biochemistry. 101: 927-36. PMID 17177290 DOI: 10.1002/Jcb.21148 |
0.482 |
|
2006 |
Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Fidler IJ. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. The American Journal of Pathology. 169: 2054-65. PMID 17148668 DOI: 10.2353/Ajpath.2006.060653 |
0.511 |
|
2006 |
Fidler IJ. Models for spontaneous metastasis. Cancer Research. 66: 9787. PMID 17018641 DOI: 10.1158/0008-5472.Can-06-2396 |
0.342 |
|
2006 |
Busby JE, Kim SJ, Yazici S, Nakamura T, Kim JS, He J, Maya M, Wang X, Do KA, Fan D, Fidler IJ. Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells. The Prostate. 66: 1788-98. PMID 17013882 DOI: 10.1002/Pros.20519 |
0.429 |
|
2006 |
Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Hamilton SR, Fidler IJ. Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential. International Journal of Cancer. 119: 2567-74. PMID 16988946 DOI: 10.1002/Ijc.22229 |
0.466 |
|
2006 |
Rebhun RB, Langley RR, Yokoi K, Fan D, Gershenwald JE, Fidler IJ. Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. Neoplasia (New York, N.Y.). 8: 747-57. PMID 16984732 DOI: 10.1593/Neo.06322 |
0.698 |
|
2006 |
Zhang W, Tsan R, Nam DH, Lu W, Fidler IJ. Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to melanotic by inhibition of AKT. Neoplasia (New York, N.Y.). 8: 543-50. PMID 16867216 DOI: 10.1593/Neo.05655 |
0.408 |
|
2006 |
Baker CH, Pino MS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors. Neoplasia (New York, N.Y.). 8: 470-6. PMID 16820093 DOI: 10.1593/Neo.06172 |
0.465 |
|
2006 |
Baker CH, Trevino JG, Summy JM, Zhang F, Caron A, Nesbit M, Gallick GE, Fidler IJ. Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice. International Journal of Oncology. 29: 125-38. PMID 16773192 DOI: 10.3892/Ijo.29.1.125 |
0.48 |
|
2006 |
Kim SJ, Uehara H, Yazici S, Busby JE, Nakamura T, He J, Maya M, Logothetis C, Mathew P, Wang X, Do KA, Fan D, Fidler IJ. Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. Journal of the National Cancer Institute. 98: 783-93. PMID 16757703 DOI: 10.1093/Jnci/Djj211 |
0.459 |
|
2006 |
Mathew P, Thall PF, Johnson MM, Oh WK, Meluch AA, Morris MJ, Troncoso P, Bucana CD, Fidler IJ, Logothetis CJ. Preliminary results of a randomized placebo-controlled double-blind trial of weekly docetaxel combined with imatinib in men with metastatic androgen-independent prostate cancer (AIPC) and bone metastases (BM) Journal of Clinical Oncology. 24: 4562-4562. DOI: 10.1200/Jco.2006.24.18_Suppl.4562 |
0.322 |
|
2006 |
Mathew P, Thall P, Wen S, Horne E, Johnson M, Oh W, Morris M, Logothetis C, Fidler I, Bucana C. 79 POSTER Correlative results of in-vivo monitoring of platelet-derived growth factor receptor (PDGFR) activation status in a randomized placebocontrolled trial of docetaxel +/− imatinib in castration-resistant prostate cancer (CRPC) and bone metastases (BM) European Journal of Cancer Supplements. 4: 28. DOI: 10.1016/S1359-6349(06)70085-4 |
0.313 |
|
2006 |
Busby JE, Kim S, Yazici MS, Fan D, Fidler IJ. 792: Therapy of Multidrug Resistant Prostate Cancer by Targeting the Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor On Tumor-Associated Endothelial Cells Journal of Urology. 175: 256-256. DOI: 10.1016/S0022-5347(18)33028-3 |
0.4 |
|
2005 |
Weihua Z, Tsan R, Schroit AJ, Fidler IJ. Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling. Cancer Research. 65: 11529-35. PMID 16357162 DOI: 10.1158/0008-5472.Can-05-2718 |
0.384 |
|
2005 |
Cheng H, Langley RR, Wu Q, Wu W, Feng J, Tsan R, Fan D, Fidler IJ. Construction of a novel constitutively active chimeric EGFR to identify new targets for therapy. Neoplasia (New York, N.Y.). 7: 1065-72. PMID 16354589 DOI: 10.1593/Neo.05553 |
0.387 |
|
2005 |
Nilsson MB, Langley RR, Fidler IJ. Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Research. 65: 10794-800. PMID 16322225 DOI: 10.1158/0008-5472.Can-05-0623 |
0.668 |
|
2005 |
Yokoi K, Sasaki T, Bucana CD, Fan D, Baker CH, Kitadai Y, Kuwai T, Abbruzzese JL, Fidler IJ. Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. Cancer Research. 65: 10371-80. PMID 16288027 DOI: 10.1158/0008-5472.Can-05-1698 |
0.488 |
|
2005 |
Yokoi K, Shih LCN, Kobayashi R, Koomen J, Hawke D, Li D, Hamilton SR, Abbruzzese JL, Coombes KR, Fidler IJ. Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer International Journal of Oncology. 27: 1361-1369. PMID 16211233 DOI: 10.3892/Ijo.27.5.1361 |
0.387 |
|
2005 |
Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia (New York, N.Y.). 7: 696-704. PMID 16026649 DOI: 10.1593/Neo.05193 |
0.502 |
|
2005 |
Thaker PH, Yazici S, Nilsson MB, Yokoi K, Tsan RZ, He J, Kim SJ, Fidler IJ, Sood AK. Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4923-33. PMID 16000591 DOI: 10.1158/1078-0432.Ccr-04-2060 |
0.648 |
|
2005 |
Yazici S, Kim SJ, Busby JE, He J, Thaker P, Yokoi K, Fan D, Fidler IJ. Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice. The Prostate. 65: 203-15. PMID 15948138 DOI: 10.1002/Pros.20283 |
0.381 |
|
2005 |
Younes MN, Yigitbasi OG, Park YW, Kim SJ, Jasser SA, Hawthorne VS, Yazici YD, Mandal M, Bekele BN, Bucana CD, Fidler IJ, Myers JN. Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation. Cancer Research. 65: 4716-27. PMID 15930290 DOI: 10.1158/0008-5472.Can-04-4196 |
0.419 |
|
2005 |
Yokoi K, Thaker PH, Yazici S, Rebhun RR, Nam DH, He J, Kim SJ, Abbruzzese JL, Hamilton SR, Fidler IJ. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Research. 65: 3716-25. PMID 15867367 DOI: 10.1158/0008-5472.Can-04-3700 |
0.512 |
|
2005 |
Kim SJ, Uehara H, Yazici S, He J, Langley RR, Mathew P, Fan D, Fidler IJ. Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer. Cancer Research. 65: 3707-15. PMID 15867366 DOI: 10.1158/0008-5472.Can-04-3601 |
0.435 |
|
2005 |
Uehara H, Troncoso P, Johnston D, Bucana CD, Dinney C, Dong Z, Fidler IJ, Pettaway CA. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate. 64: 40-9. PMID 15651067 DOI: 10.1002/Pros.20223 |
0.365 |
|
2005 |
Cheng H, Cenciarelli C, Nelkin G, Tsan R, Fan D, Cheng-Mayer C, Fidler IJ. Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth. Molecular and Cellular Biology. 25: 44-59. PMID 15601829 DOI: 10.1128/Mcb.25.1.44-59.2005 |
0.41 |
|
2005 |
Kim SJ, Sertac Yazici M, Busby E, He J, Fan D, Fidler IJ. 568: Treatment of Human Prostate Cancer Cells Growing in the Bone of Nude Mice with AEE788, Inhibitor of Epidermal Growth Factor and Vascular Growth Factor Receptor, and Paclitaxel Journal of Urology. 173: 155-155. DOI: 10.1016/S0022-5347(18)34808-0 |
0.385 |
|
2005 |
Kim SJ, Yazici MS, Uehara H, Busby E, He J, Fan D, Fidler IJ. 393: Bypass of Drug-Resistance by Antivascular Therapy with Protein Tyrosine Kinase Inhibitor, STI571, in Human Prostate Cancer Bone Metastasis Model of Nude Mice Journal of Urology. 173: 107-108. DOI: 10.1016/S0022-5347(18)34646-9 |
0.324 |
|
2004 |
Yokoi K, Raber MN, Shih LN, Li D, Hamilton SR, Fidler IJ, Abbruzzese JL. Serum Amyloid A (SAA) in Patients with Pancreatic Carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9649. PMID 28016244 DOI: 10.1200/Jco.2004.22.90140.9649 |
0.356 |
|
2004 |
Onn A, Isobe T, Wu W, Itasaka S, Shintani T, Shibuya K, Kenji Y, O'reilly MS, Fidler IJ, Herbst RS. Epidermal growth factor receptor tyrosine kinase inhibitor does not improve paclitaxel effect in an orthotopic mouse model of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8613-9. PMID 15623645 DOI: 10.1158/1078-0432.Ccr-04-1241 |
0.407 |
|
2004 |
Yigitbasi OG, Younes MN, Doan D, Jasser SA, Schiff BA, Bucana CD, Bekele BN, Fidler IJ, Myers JN. Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade. Cancer Research. 64: 7977-84. PMID 15520205 DOI: 10.1158/0008-5472.Can-04-1477 |
0.493 |
|
2004 |
Fidler IJ, Ellis LM. Neoplastic angiogenesis--not all blood vessels are created equal. The New England Journal of Medicine. 351: 215-6. PMID 15254281 DOI: 10.1056/Nejmp048080 |
0.408 |
|
2004 |
Kim SJ, Uehara H, Yazici S, Langley RR, He J, Tsan R, Fan D, Killion JJ, Fidler IJ. Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice. Cancer Research. 64: 4201-8. PMID 15205332 DOI: 10.1158/0008-5472.Can-03-3763 |
0.434 |
|
2004 |
Mathew P, Fidler IJ, Logothetis CJ. Combination docetaxel and platelet-derived growth factor receptor inhibition with imatinib mesylate in prostate cancer. Seminars in Oncology. 31: 24-9. PMID 15176001 DOI: 10.1053/J.Seminoncol.2004.03.037 |
0.351 |
|
2004 |
Langley RR, Fan D, Tsan RZ, Rebhun R, He J, Kim SJ, Fidler IJ. Activation of the platelet-derived growth factor-receptor enhances survival of murine bone endothelial cells. Cancer Research. 64: 3727-30. PMID 15172974 DOI: 10.1158/0008-5472.Can-03-3863 |
0.662 |
|
2004 |
Yokoi K, Fidler IJ. Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2299-306. PMID 15073105 DOI: 10.1158/1078-0432.Ccr-03-0488 |
0.347 |
|
2004 |
Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ. Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecologic Oncology. 93: 78-86. PMID 15047217 DOI: 10.1016/J.Ygyno.2003.12.041 |
0.469 |
|
2004 |
Apte SM, Fan D, Killion JJ, Fidler IJ. Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 897-908. PMID 14871965 DOI: 10.1158/1078-0432.Ccr-1151-3 |
0.396 |
|
2004 |
Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 136-43. PMID 14734462 DOI: 10.1158/1078-0432.Ccr-0373-3 |
0.352 |
|
2003 |
McCarty MF, Bielenberg DR, Nilsson MB, Gershenwald JE, Barnhill RL, Ahearne P, Bucana CD, Fidler IJ. Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis. Melanoma Research. 13: 379-87. PMID 12883364 DOI: 10.1097/00008390-200308000-00007 |
0.802 |
|
2003 |
Langley RR, Ramirez KM, Tsan RZ, Van Arsdall M, Nilsson MB, Fidler IJ. Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis. Cancer Research. 63: 2971-6. PMID 12782605 |
0.675 |
|
2003 |
Weber KL, Doucet M, Price JE, Baker C, Kim SJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice. Cancer Research. 63: 2940-7. PMID 12782601 |
0.384 |
|
2003 |
Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Reviews. Cancer. 3: 453-8. PMID 12778135 DOI: 10.1038/Nrc1098 |
0.404 |
|
2003 |
Fidler IJ, Kripke ML. Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population. Nature Genetics. 34: 23; author reply 25. PMID 12721548 DOI: 10.1038/Ng0503-23A |
0.369 |
|
2003 |
Ozawa S, Lu W, Bucana CD, Kanayama HO, Shinohara H, Fidler IJ, Dong Z. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International Journal of Oncology. 22: 977-84. PMID 12684662 DOI: 10.3892/Ijo.22.5.977 |
0.45 |
|
2003 |
Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. Journal of the National Cancer Institute. 95: 458-70. PMID 12644539 DOI: 10.1093/Jnci/95.6.458 |
0.389 |
|
2003 |
Kim SJ, Uehara H, Karashima T, Shepherd DL, Killion JJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1200-10. PMID 12631626 |
0.327 |
|
2003 |
Fidler IJ, Yoneda J, Herrera C, Wood J, Xu L. Specific keynote: molecular determinants of angiogenesis in ovarian cancer. Gynecologic Oncology. 88: S29-36; discussion S. PMID 12586082 DOI: 10.1006/Gyno.2002.6680 |
0.311 |
|
2003 |
Onn A, Fidler IJ. Metastatic potential of human neoplasms. In Vivo (Athens, Greece). 16: 423-9. PMID 12494885 |
0.375 |
|
2003 |
Takahashi Y, Kitadai Y, Ellis LM, Bucana CD, Fidler IJ, Mai M. Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma. Japanese Journal of Cancer Research : Gann. 93: 1258-65. PMID 12460468 DOI: 10.1111/J.1349-7006.2002.Tb01232.X |
0.359 |
|
2003 |
Kedar D, Baker CH, Killion JJ, Dinney CP, Fidler IJ. Blockade of the epidermal growth factor receptor signaling inhibits angiogenesis leading to regression of human renal cell carcinoma growing orthotopically in nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3592-600. PMID 12429651 |
0.342 |
|
2003 |
Fidler IJ. Critical determinants of metastasis. Seminars in Cancer Biology. 12: 89-96. PMID 12027580 DOI: 10.1006/Scbi.2001.0416 |
0.472 |
|
2003 |
Onn A, Correa AM, Gilcrease M, Massarelli E, Bucana CD, Ki Hong W, Fidler IJ, Putnam JB, Herbst RS. P-484 Synchronous overexpression of epidermal growth factor receptor and HER2-NEU is a predictor of poor outcome in patients with stage I non-small cell lung cancer Lung Cancer. 41: S213. DOI: 10.1016/S0169-5002(03)92451-2 |
0.34 |
|
2003 |
Kohn EC, Fidler IJ, Fishman D, Jaffe R, Liotta LA, Van Trappen P, Mills GB, Trope C. Discussion: Metastasis and Angiogenesis in Epithelial Ovarian Cancer Gynecologic Oncology. 88: S37-S42. DOI: 10.1006/Gyno.2002.6681 |
0.355 |
|
2002 |
McCarty MF, Bielenberg D, Donawho C, Bucana CD, Fidler IJ. Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms. Clinical & Experimental Metastasis. 19: 609-15. PMID 12498390 DOI: 10.1023/A:1020923326441 |
0.728 |
|
2002 |
Fidler IJ. The organ microenvironment and cancer metastasis Differentiation. 70: 498-505. PMID 12492492 DOI: 10.1046/J.1432-0436.2002.700904.X |
0.472 |
|
2002 |
Fan D, Liaw A, Denkins YM, Collins JH, Van Arsdall M, Chang JL, Chakrabarty S, Nguyen D, Kruzel E, Fidler IJ. Type-1 transforming growth factor-beta differentially modulates tumoricidal activity of murine peritoneal macrophages against metastatic variants of the B16 murine melanoma. Journal of Experimental Therapeutics & Oncology. 2: 286-97. PMID 12416032 DOI: 10.1046/J.1359-4117.2002.01053.X |
0.317 |
|
2002 |
Baker CH, Kedar D, McCarty MF, Tsan R, Weber KL, Bucana CD, Fidler IJ. Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. The American Journal of Pathology. 161: 929-38. PMID 12213721 DOI: 10.1016/S0002-9440(10)64253-8 |
0.767 |
|
2002 |
Huang S, Van Arsdall M, Tedjarati S, McCarty M, Wu W, Langley R, Fidler IJ. Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice. Journal of the National Cancer Institute. 94: 1134-42. PMID 12165638 DOI: 10.1093/Jnci/94.15.1134 |
0.736 |
|
2002 |
Myers JN, Holsinger FC, Bekele BN, Li E, Jasser SA, Killion JJ, Fidler IJ. Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade: a preliminary report. Archives of Otolaryngology--Head & Neck Surgery. 128: 875-9. PMID 12162763 DOI: 10.1001/Archotol.128.8.875 |
0.37 |
|
2002 |
Lu W, Dong Z, Donawho C, Fidler IJ. Specific immunotherapy against occult cancer metastases. International Journal of Cancer. 100: 480-5. PMID 12115534 DOI: 10.1002/Ijc.10494 |
0.391 |
|
2002 |
McCarty MF, Baker CH, Bucana CD, Fidler IJ. Quantitative and qualitative in vivo angiogenesis assay. International Journal of Oncology. 21: 5-10. PMID 12063542 DOI: 10.3892/Ijo.21.1.5 |
0.727 |
|
2002 |
Gershenwald JE, Fidler IJ. Cancer. Targeting lymphatic metastasis. Science (New York, N.Y.). 296: 1811-2. PMID 12052939 DOI: 10.1126/Science.10731318 |
0.413 |
|
2002 |
Huang S, Bucana CD, Van Arsdall M, Fidler IJ. Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene. 21: 2504-12. PMID 11971185 DOI: 10.1038/Sj.Onc.1205341 |
0.481 |
|
2002 |
Baker CH, Solorzano CC, Fidler IJ. Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Research. 62: 1996-2003. PMID 11929816 |
0.337 |
|
2002 |
Fidler IJ, Yano S, Zhang RD, Fujimaki T, Bucana CD. The seed and soil hypothesis: vascularisation and brain metastases. The Lancet. Oncology. 3: 53-7. PMID 11905606 DOI: 10.1016/S1470-2045(01)00622-2 |
0.375 |
|
2002 |
Kuniyasu H, Yasui W, Pettaway CA, Yano S, Oue N, Tahara E, Fidler IJ. Interferon-alpha prevents selection of doxorubicin-resistant undifferentiated-androgen-insensitive metastatic human prostate cancer cells. The Prostate. 49: 19-29. PMID 11550207 DOI: 10.1002/Pros.1114 |
0.378 |
|
2002 |
Herrera CA, Xu L, Bucana CD, Silva EVG, Hess KR, Gershenson DM, Fidler IJ. Expression of metastasis-related genes in human epithelial ovarian tumors International Journal of Oncology. 20: 5-13. DOI: 10.3892/Ijo.20.1.5 |
0.325 |
|
2001 |
Solorzano CC, Baker CH, Bruns CJ, Killion JJ, Ellis LM, Wood J, Fidler IJ. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biotherapy & Radiopharmaceuticals. 16: 359-70. PMID 11776753 DOI: 10.1089/108497801753354267 |
0.475 |
|
2001 |
Baker CH, Solorzano CC, Fidler IJ. Angiogenesis and cancer metastasis: antiangiogenic therapy of human pancreatic adenocarcinoma. International Journal of Clinical Oncology. 6: 59-65. PMID 11706751 DOI: 10.1007/Pl00012085 |
0.355 |
|
2001 |
Kuniyasu H, Abbruzzese JL, Cleary KR, Fidler IJ. Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma. International Journal of Oncology. 19: 681-5. PMID 11562741 DOI: 10.3892/Ijo.19.4.681 |
0.422 |
|
2001 |
Huang S, Pettaway CA, Uehara H, Bucana CD, Fidler IJ. Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene. 20: 4188-97. PMID 11464285 DOI: 10.1038/Sj.Onc.1204535 |
0.408 |
|
2001 |
Ozawa S, Shinohara H, Kanayama HO, Bruns CJ, Bucana CD, Ellis LM, Davis DW, Fidler IJ. Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. Neoplasia (New York, N.Y.). 3: 154-64. PMID 11420751 DOI: 10.1038/Sj.Neo.7900128 |
0.408 |
|
2001 |
Kim SJ, Uehara H, Karashima T, Mccarty M, Shih N, Fidler IJ. Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (New York, N.Y.). 3: 33-42. PMID 11326314 DOI: 10.1038/Sj.Neo.7900124 |
0.735 |
|
2001 |
Berry KK, Varney ML, Dave BJ, Bucana CD, Fidler IJ, Singh RK. Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 11: 54-60. PMID 11285034 DOI: 10.1046/J.1525-1438.2001.011001054.X |
0.364 |
|
2001 |
Slaton JW, Inoue K, Perrotte P, El-Naggar AK, Swanson DA, Fidler IJ, Dinney CP. Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma. The American Journal of Pathology. 158: 735-43. PMID 11159211 DOI: 10.1016/S0002-9440(10)64016-3 |
0.392 |
|
2001 |
Xu L, Fidler IJ. Interleukin 8: an autocrine growth factor for human ovarian cancer. Oncology Research. 12: 97-106. PMID 11132928 DOI: 10.3727/096504001108747567 |
0.329 |
|
2001 |
Yano S, Shinohara H, Herbst RS, Kuniyasu H, Bucana CD, Ellis LM, Fidler IJ. Production of experimental malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells. The American Journal of Pathology. 157: 1893-903. PMID 11106562 DOI: 10.1016/S0002-9440(10)64828-6 |
0.441 |
|
2001 |
Andreeff M, Studeny M, Zoltick P, Zompetta C, Wilson J, Fidler IJ, Marini F. Mesenchymal stem cells (MSC) as carriers of biologically active molecules in cancer and leukemia therapy European Journal of Cancer. 37: S81. DOI: 10.1016/S0959-8049(01)80445-7 |
0.322 |
|
2000 |
Kanayama H, Yano S, Kim SJ, Ozawa S, Ellis LM, Fidler IJ. Expression of vascular endothelial growth factor by human renal cancer cells enhances angiogenesis of primary tumors and production of ascites but not metastasis to the lungs in nude mice. Clinical & Experimental Metastasis. 17: 831-40. PMID 11089881 DOI: 10.1023/A:1006792007063 |
0.464 |
|
2000 |
Kuniyasu H, Yasui W, Shinohara H, Yano S, Ellis LM, Wilson MR, Bucana CD, Rikita T, Tahara E, Fidler IJ. Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer. The American Journal of Pathology. 157: 1523-35. PMID 11073812 DOI: 10.1016/S0002-9440(10)64790-6 |
0.457 |
|
2000 |
Shinohara H, Fan D, Ozawa S, Yano S, Van Arsdell M, Viner JL, Beers R, Pastan I, Fidler IJ. Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin. International Journal of Oncology. 17: 643-51. PMID 10995873 DOI: 10.3892/Ijo.17.4.643 |
0.442 |
|
2000 |
Huang S, DeGuzman A, Bucana CD, Fidler IJ. Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity. Cytokines, Cellular & Molecular Therapy. 6: 9-17. PMID 10976534 DOI: 10.1080/13684730050515868 |
0.318 |
|
2000 |
Kumar R, Eue I, Dong Z, Killion JJ, Fidler IJ. Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptide JT3002. Cancer Biotherapy & Radiopharmaceuticals. 12: 333-40. PMID 10851483 DOI: 10.1089/Cbr.1997.12.333 |
0.337 |
|
2000 |
Juang SH, Xie K, Xu L, Wang Y, Yoneda J, Fidler IJ. Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma. Cancer Biotherapy & Radiopharmaceuticals. 12: 167-75. PMID 10851463 DOI: 10.1089/Cbr.1997.12.167 |
0.459 |
|
2000 |
Bielenberg DR, Fidler IJ, Bucana CD. Constitutive expression of interferon beta in differentiated epithelial cells exposed to environmental stimuli. Cancer Biotherapy & Radiopharmaceuticals. 13: 375-82. PMID 10851428 DOI: 10.1089/Cbr.1998.13.375 |
0.351 |
|
2000 |
Yoneda J, Killion JJ, Bucana CD, Fidler IJ. Angiogenesis and growth of murine colon carcinoma are dependent on infiltrating leukocytes. Cancer Biotherapy & Radiopharmaceuticals. 14: 221-30. PMID 10850306 DOI: 10.1089/Cbr.1999.14.221 |
0.451 |
|
2000 |
Shinohara H, Bucana CD, Killion JJ, Fidler IJ. Intensified regression of colon cancer liver metastases in mice treated with irinotecan and the immunomodulator JBT 3002. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 321-31. PMID 10838661 DOI: 10.1097/00002371-200005000-00005 |
0.445 |
|
2000 |
Fidler IJ, Ellis LM. Chemotherapeutic drugs--more really is not better. Nature Medicine. 6: 500-2. PMID 10802697 DOI: 10.1038/74969 |
0.312 |
|
2000 |
Kumar R, Xie K, Eue I, Dong Z, Killion JJ, Fidler IJ. Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the synthetic bacterial lipopeptide JBT 3002. International Journal of Immunopharmacology. 22: 431-43. PMID 10727754 DOI: 10.1016/S0192-0561(00)00008-4 |
0.308 |
|
2000 |
Fidler IJ, Schackert G, Zhang RD, Radinsky R, Fujimaki T. The biology of melanoma brain metastasis. Cancer Metastasis Reviews. 18: 387-400. PMID 10721492 DOI: 10.1023/A:1006329410433 |
0.376 |
|
2000 |
Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhuang Y, Su B. Mekk3 is essential for early embryonic cardiovascular development. Nature Genetics. 24: 309-13. PMID 10700190 DOI: 10.1038/73550 |
0.696 |
|
2000 |
Shinohara H, Yano S, Bucana CD, Fidler IJ. Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 2728-37. PMID 10679114 DOI: 10.4049/Jimmunol.164.5.2728 |
0.452 |
|
2000 |
Xu L, Yoneda J, Herrera C, Wood J, Killion JJ, Fidler IJ. Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. International Journal of Oncology. 16: 445-54. PMID 10675474 DOI: 10.3892/Ijo.16.3.445 |
0.463 |
|
2000 |
Yano S, Herbst R, Sone S, Fidler I. Production of malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells Lung Cancer. 29: 217. DOI: 10.1016/S0169-5002(00)80743-6 |
0.397 |
|
1999 |
Bruns CJ, Harbison MT, Kuniyasu H, Eue I, Fidler IJ. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice Neoplasia (New York, N.Y.). 1: 50-62. PMID 10935470 DOI: 10.1038/Sj.Neo.7900005 |
0.47 |
|
1999 |
Multani AS, Ozen M, Sen S, Mandal AK, Price JE, Fan D, Radinsky R, Ali-Osman F, Von Eschenbach AC, Fidler IJ, Pathak S. Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin. International Journal of Oncology. 15: 423-9. PMID 10427120 DOI: 10.3892/Ijo.15.3.423 |
0.421 |
|
1999 |
Fidler IJ. Critical determinants of cancer metastasis: rationale for therapy. Cancer Chemotherapy and Pharmacology. S3-10. PMID 10357552 DOI: 10.1007/S002800051091 |
0.503 |
|
1999 |
Killion JJ, Radinsky R, Fidler IJ. Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Reviews. 17: 279-84. PMID 10352881 DOI: 10.1023/A:1006140513233 |
0.433 |
|
1999 |
Bielenberg DR, McCarty MF, Bucana CD, Yuspa SH, Morgan D, Arbeit JM, Ellis LM, Cleary KR, Fidler IJ. Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells. The Journal of Investigative Dermatology. 112: 802-9. PMID 10233775 DOI: 10.1046/J.1523-1747.1999.00566.X |
0.72 |
|
1999 |
Bielenberg DR, Bucana CD, Sanchez R, Mulliken JB, Folkman J, Fidler IJ. Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta. International Journal of Oncology. 14: 401-8. PMID 10024670 DOI: 10.3892/Ijo.14.3.401 |
0.355 |
|
1999 |
Kumar R, Yoneda J, Fidler IJ, Dong Z. GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages and poorly tumorigenic in immune-compromised mice. Journal of Leukocyte Biology. 65: 102-8. PMID 9886252 DOI: 10.1002/Jlb.65.1.102 |
0.444 |
|
1999 |
Xu L, Xie K, Fidler IJ. Therapy of human ovarian cancer by transfection with the murine interferon beta gene: role of macrophage-inducible nitric oxide synthase. Human Gene Therapy. 9: 2699-708. PMID 9874268 DOI: 10.1089/Hum.1998.9.18-2699 |
0.456 |
|
1999 |
Slaton JW, Perrotte P, Inoue K, El-Naggar A, Fidler IJ, Swanson DA, Dinney CPN. Ratio Of Matrix Metalloproteases (Mmp) To E-Cadherin (Ecad) Expression Is An Independent Predictor Of Metastasis In Renal Cell Carcinoma (Rcc) The Journal of Urology. 147. DOI: 10.1097/00005392-199904010-00589 |
0.303 |
|
1999 |
Dinney CPN, Slaton JW, Inoue K, Perrotte P, El-Naggar A, Fidler I, Swanson DA. The Prognostic Significance Of Angiogenic Factor Expression In Renal Cell Carcinoma (Rcc) The Journal of Urology. 140. DOI: 10.1097/00005392-199904010-00564 |
0.319 |
|
1998 |
Bielenberg DR, Bucana CD, Sanchez R, Donawho CK, Kripke ML, Fidler IJ. Molecular regulation of UVB-induced cutaneous angiogenesis. The Journal of Investigative Dermatology. 111: 864-72. PMID 9804351 DOI: 10.1046/J.1523-1747.1998.00378.X |
0.382 |
|
1998 |
Eue I, Kumar R, Dong Z, Killion JJ, Fidler IJ. Induction of nitric oxide production and tumoricidal properties in murine macrophages by a new synthetic lipopeptide JBT3002 encapsulated in liposomes. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 340-51. PMID 9789196 DOI: 10.1097/00002371-199809000-00002 |
0.361 |
|
1998 |
Anzai H, Kitadai Y, Bucana CD, Sanchez R, Omoto R, Fidler IJ. Expression of metastasis-related genes in surgical specimens of human gastric cancer can predict disease recurrence. European Journal of Cancer (Oxford, England : 1990). 34: 558-65. PMID 9713309 DOI: 10.1016/S0959-8049(97)10075-2 |
0.326 |
|
1998 |
Dong Z, Yoneda J, Kumar R, Fidler IJ. Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce granulocyte/macrophage colony-stimulating factor. The Journal of Experimental Medicine. 188: 755-63. PMID 9705957 DOI: 10.1084/Jem.188.4.755 |
0.447 |
|
1998 |
Killion JJ, Fidler IJ. Therapy of cancer metastasis by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators. Pharmacology & Therapeutics. 78: 141-54. PMID 9690815 DOI: 10.1016/S0163-7258(98)00004-7 |
0.414 |
|
1998 |
Dong Z, Juang SH, Kumar R, Eue I, Xie K, Bielenberg D, Lu W, Bucana C, Yang X, Fidler IJ. Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with a retroviral vector harboring the interferon-beta gene. Cancer Immunology, Immunotherapy : Cii. 46: 137-46. PMID 9625537 DOI: 10.1007/S002620050472 |
0.422 |
|
1998 |
Dong Z, Killion JJ, Kumar R, Eue I, Yang X, Lu W, Su B, Fidler IJ. Activation of cytokine production, tumoricidal properties, and tyrosine phosphorylation of MAPKs in human monocytes by a new synthetic lipopeptide, JBT3002. Journal of Leukocyte Biology. 63: 766-74. PMID 9620671 DOI: 10.1002/Jlb.63.6.766 |
0.342 |
|
1998 |
Juang SH, Xie K, Xu L, Shi Q, Wang Y, Yoneda J, Fidler IJ. Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the murine inducible nitric oxide synthase gene. Human Gene Therapy. 9: 845-54. PMID 9581907 DOI: 10.1089/Hum.1998.9.6-845 |
0.411 |
|
1998 |
Xie K, Fidler IJ. Therapy of cancer metastasis by activation of the inducible nitric oxide synthase Cancer and Metastasis Reviews. 17: 55-75. PMID 9544423 DOI: 10.1023/A:1005956721457 |
0.49 |
|
1998 |
Yoneda J, Kuniyasu H, Crispens MA, Price JE, Bucana CD, Fidler IJ. Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. Journal of the National Cancer Institute. 90: 447-54. PMID 9521169 DOI: 10.1093/Jnci/90.6.447 |
0.388 |
|
1998 |
Kumar R, Yoneda J, Bucana CD, Fidler IJ. Regulation of distinct steps of angiogenesis by different angiogenic molecules. International Journal of Oncology. 12: 749-57. PMID 9499433 DOI: 10.3892/Ijo.12.4.749 |
0.372 |
|
1997 |
Nemeth MA, Wilson MR, Fidler IJ, Pathak S. Increasing metastatic potential is associated with induced chromosome 14 translocations in a previously nonmetastatic murine melanoma cell line. Cancer Genetics and Cytogenetics. 98: 119-25. PMID 9332476 DOI: 10.1016/S0165-4608(96)00421-9 |
0.363 |
|
1997 |
Yoon SS, Fidler IJ, Beltran PJ, Bucana CD, Wang YF, Fan D. Intratumoral heterogeneity for and epigenetic modulation of mdr-1 expression in murine melanoma. Melanoma Research. 7: 275-87. PMID 9293477 DOI: 10.1097/00008390-199708000-00002 |
0.402 |
|
1997 |
Xie K, Wang Y, Huang S, Xu L, Bielenberg D, Salas T, McConkey DJ, Jiang W, Fidler IJ. Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. Oncogene. 15: 771-9. PMID 9266963 DOI: 10.1038/Sj.Onc.1201239 |
0.375 |
|
1997 |
Dong Z, Kumar R, Yang X, Fidler IJ. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell. 88: 801-10. PMID 9118223 DOI: 10.1016/S0092-8674(00)81926-1 |
0.426 |
|
1997 |
Xie K, Huang S, Dong Z, Juang SH, Wang Y, Fidler IJ. Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene. Journal of the National Cancer Institute. 89: 421-7. PMID 9091643 DOI: 10.1093/Jnci/89.6.421 |
0.444 |
|
1997 |
Ellis LM, Fidler IJ. Angiogenesis and metastasis. European Journal of Cancer (Oxford, England : 1990). 2451-60. PMID 9059333 DOI: 10.1016/S0959-8049(96)00389-9 |
0.356 |
|
1997 |
Beltran PJ, Fan D, Fidler IJ, O'Brian CA. Chemosensitization of cancer cells by the staurosporine derivative CGP 41251 in association with decreased P-glycoprotein phosphorylation Biochemical Pharmacology. 53: 245-247. PMID 9037258 DOI: 10.1016/S0006-2952(96)00718-6 |
0.345 |
|
1997 |
Singh RK, Gutman M, Llansa N, Fidler IJ. Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 16: 577-84. PMID 8877727 DOI: 10.1089/Jir.1996.16.577 |
0.333 |
|
1996 |
Dave BJ, Singh R, Fidler IJ, Pathak S. Chromosome 14 alteration is associated with increased collagenase expression and the metastatic potential of murine melanomas. Cancer Genetics and Cytogenetics. 92: 66-72. PMID 8956875 DOI: 10.1016/S0165-4608(96)00160-4 |
0.36 |
|
1996 |
Xie K, Huang S, Wang Y, Beltran PJ, Juang SH, Dong Z, Reed JC, McDonnell TJ, McConkey DJ, Fidler IJ. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis Cancer Immunology, Immunotherapy. 43: 109-115. PMID 8954145 DOI: 10.1007/S002620050310 |
0.399 |
|
1996 |
Fujimaki T, Price JE, Fan D, Bucana CD, Itoh K, Kirino T, Fidler IJ. Selective growth of human melanoma cells in the brain parenchyma of nude mice. Melanoma Research. 6: 363-71. PMID 8908596 DOI: 10.1097/00008390-199610000-00003 |
0.312 |
|
1996 |
Xie K, Dong Z, Fidler IJ. Activation of nitric oxide synthase gene for inhibition of cancer metastasis. Journal of Leukocyte Biology. 59: 797-803. PMID 8691063 DOI: 10.1002/Jlb.59.6.797 |
0.478 |
|
1996 |
Anzai H, Kitadai Y, Bucana CD, Sanchez R, Omoto R, Fidler IJ. Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas. Differentiation; Research in Biological Diversity. 60: 119-27. PMID 8641546 DOI: 10.1046/J.1432-0436.1996.6020119.X |
0.334 |
|
1995 |
Killion JJ, Fidler IJ. Systemic targeting of liposome-encapsulated immunomodulators to macrophages for treatment of cancer metastasis. Immunomethods. 4: 273-9. PMID 7820457 DOI: 10.1006/Immu.1994.1029 |
0.441 |
|
1995 |
Gutman M, Fidler IJ. Biology of human colon cancer metastasis. World Journal of Surgery. 19: 226-34. PMID 7754628 DOI: 10.1007/Bf00308631 |
0.498 |
|
1995 |
Singh RK, Gutman M, Bucana CD, Sanchez R, Llansa N, Fidler IJ. Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 92: 4562-6. PMID 7753843 DOI: 10.1073/Pnas.92.10.4562 |
0.339 |
|
1995 |
Gutman M, Beltran PJ, Fan D, Delworth MG, Singh RK, Wilson MR, Fidler IJ. Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells. Melanoma Research. 5: 147-54. PMID 7640515 DOI: 10.1097/00008390-199506000-00002 |
0.391 |
|
1995 |
Fidler IJ. Modulation of the organ microenvironment for treatment of cancer metastasis. Journal of the National Cancer Institute. 87: 1588-92. PMID 7563201 DOI: 10.1093/Jnci/87.21.1588 |
0.308 |
|
1995 |
Ellis LM, Fidler IJ. Angiogenesis and breast cancer metastasis The Lancet. 346: 388-390. PMID 7542721 DOI: 10.1016/S0140-6736(95)92774-3 |
0.302 |
|
1995 |
Xie K, Huang S, Dong Z, Juang SH, Gutman M, Xie QW, Nathan C, Fidler IJ. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. The Journal of Experimental Medicine. 181: 1333-43. PMID 7535333 DOI: 10.1084/Jem.181.4.1333 |
0.387 |
|
1995 |
Gutman M, Singh RK, Yoon S, Xie K, Bucana CD, Fidler IJ. Leukocyte-induced angiogenesis and subcutaneous growth of B16 melanoma. Cancer Biotherapy. 9: 163-70. PMID 7529086 DOI: 10.1089/Cbr.1994.9.163 |
0.441 |
|
1995 |
Dinney CPN, Fishbeck R, Singh RK, Eve B, Pathak S, Brown N, Xie B, Fan D, Bucana CD, Fidler IJ, Killion JJ. Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice Journal of Urology. 154: 1532-1538. DOI: 10.1016/S0022-5347(01)66923-4 |
0.435 |
|
1994 |
Gohji K, Nakajima M, Fabra A, Bucana CD, von Eschenbach AC, Tsuruo T, Fidler IJ. Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts. Japanese Journal of Cancer Research : Gann. 85: 152-60. PMID 8144397 DOI: 10.1111/J.1349-7006.1994.Tb02076.X |
0.418 |
|
1994 |
Gohji K, Fidler IJ, Tsan R, Radinsky R, von Eschenbach AC, Tsuruo T, Nakajima M. Human recombinant interferons-beta and -gamma decrease gelatinase production and invasion by human KG-2 renal-carcinoma cells. International Journal of Cancer. 58: 380-4. PMID 8050821 DOI: 10.1002/Ijc.2910580313 |
0.339 |
|
1994 |
Huang S, Singh RK, Xie K, Gutman M, Berry KK, Bucana CD, Fidler IJ, Bar-Eli M. Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells. Cancer Immunology, Immunotherapy : Cii. 39: 231-8. PMID 7954525 DOI: 10.1007/Bf01525986 |
0.417 |
|
1994 |
Fidler IJ, Wilmanns C, Staroselsky A, Radinsky R, Dong Z, Fan D. Modulation of tumor cell response to chemotherapy by the organ environment. Cancer Metastasis Reviews. 13: 209-22. PMID 7923551 DOI: 10.1007/Bf00689637 |
0.476 |
|
1994 |
Dong Z, Radinsky R, Fan D, Tsan R, Bucana CD, Wilmanns C, Fidler IJ. Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. Journal of the National Cancer Institute. 86: 913-20. PMID 7910854 DOI: 10.1093/Jnci/86.12.913 |
0.38 |
|
1994 |
Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell. 79: 185-8. PMID 7525076 DOI: 10.1016/0092-8674(94)90187-2 |
0.343 |
|
1994 |
Fan D, Regenass U, Beltran PJ, Campbell TE, Bielenberg D, Fidler IJ. Protein kinase C inhibitor staurosporin derivative CGP 41251 reverses MDR in murine and human cancer cell lines Anti-Cancer Drugs. 5: 29. DOI: 10.1097/00001813-199409001-00065 |
0.354 |
|
1994 |
Fan D, Beltran PJ, Gutman M, Wang Y, Bucana CD, Bielenberg D, Fidler IJ. The MDR1-mediated multidrug resistance is regulated by cell density and tumor volume in colon carcinomas Anti-Cancer Drugs. 5: 8. DOI: 10.1097/00001813-199409001-00014 |
0.378 |
|
1994 |
Fidler IJ, Kleinerman ES. Clinical application of phospholipid liposomes containing macrophage activators for therapy of cancer metastasis Advanced Drug Delivery Reviews. 13: 325-340. DOI: 10.1016/0169-409X(94)90018-3 |
0.371 |
|
1993 |
Allam A, Gioioso D, Taghian A, Duffy M, Fidler IJ, Suit HD. Intrinsic radiation sensitivity: no correlation with the metastatic potential of human and murine tumor cell lines. Journal of the National Cancer Institute. 85: 1954-7. PMID 8230288 DOI: 10.1093/Jnci/85.23.1954 |
0.403 |
|
1993 |
Killion JJ, Radinsky R, Dong Z, Fishbeck R, Whitworth P, Fidler IJ. The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of the MDR phenotype. Cancer Immunology, Immunotherapy : Cii. 36: 381-6. PMID 8098991 DOI: 10.1007/Bf01742254 |
0.423 |
|
1993 |
Fabra A, Nakajima M, Bucana CD, Fidler IJ. Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice. Differentiation; Research in Biological Diversity. 52: 101-10. PMID 1286773 DOI: 10.1111/J.1432-0436.1992.Tb00504.X |
0.425 |
|
1992 |
Fidler IJ. Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis. Cancer Metastasis Reviews. 10: 229-43. PMID 1764766 DOI: 10.1007/Bf00050794 |
0.389 |
|
1992 |
Fidler IJ. The biology of cancer metastasis or, 'you cannot fix it if you do not know how it works'. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 551-4. PMID 1755831 DOI: 10.1002/bies.950131010 |
0.305 |
|
1992 |
Fidler IJ. 7th Jan Waldenström Lecture. The biology of human cancer metastasis. Acta Oncologica (Stockholm, Sweden). 30: 668-75. PMID 1659837 DOI: 10.3109/02841869109092438 |
0.508 |
|
1992 |
Staroselsky AN, Radinsky R, Fidler IJ, Pathak S, Chernajovsky Y, Frost P. The use of molecular genetic markers to demonstrate the effect of organ environment on clonal dominance in a human renal-cell carcinoma grown in nude mice. International Journal of Cancer. 51: 130-8. PMID 1563832 DOI: 10.1002/Ijc.2910510123 |
0.426 |
|
1992 |
Fidler IJ. Therapy of disseminated melanoma by liposome-activated macrophages. World Journal of Surgery. 16: 270-6. PMID 1561809 DOI: 10.1007/Bf02071531 |
0.494 |
|
1992 |
Kleinerman ES, Raymond AK, Bucana CD, Jaffe N, Harris MB, Krakoff IH, Benjamin R, Fidler IJ. Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid) Cancer Immunology Immunotherapy. 34: 211-220. PMID 1537053 DOI: 10.1007/Bf01741788 |
0.342 |
|
1992 |
Wilmanns C, Fan D, O'Brian CA, Bucana CD, Fidler IJ. Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil International Journal of Cancer. 52: 98-104. PMID 1500231 DOI: 10.1002/Ijc.2910520118 |
0.44 |
|
1992 |
Ullrich SE, Fidler IJ. Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP-PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens Journal of Leukocyte Biology. 52: 489-494. PMID 1431559 DOI: 10.1002/Jlb.52.5.489 |
0.3 |
|
1992 |
Stephenson RA, Dinney CP, Gohji K, Ordóñez NG, Killion JJ, Fidler IJ. Metastatic model for human prostate cancer using orthotopic implantation in nude mice. Journal of the National Cancer Institute. 84: 951-7. PMID 1378502 DOI: 10.1093/Jnci/84.12.951 |
0.321 |
|
1992 |
Fidler IJ. Metastasis as a consequence of aberrant homeostasis Clinical and Experimental Metastasis. 10: 5-7. DOI: 10.1007/Bf00305899 |
0.329 |
|
1991 |
Fidler IJ, Naito S, Pathak S. Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice [corrected]. Cancer Metastasis Reviews. 9: 149-65. PMID 2253314 DOI: 10.1007/Bf00046341 |
0.468 |
|
1991 |
Nakajima M, Morikawa K, Fabra A, Bucana CD, Fidler IJ. Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. Journal of the National Cancer Institute. 82: 1890-8. PMID 2174463 DOI: 10.1093/Jnci/82.24.1890 |
0.46 |
|
1991 |
Nii A, Fan D, Fidler IJ. Cytotoxic potential of liposomes containing tumor necrosis factor-alpha against sensitive and resistant target cells. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 10: 13-9. PMID 2012796 DOI: 10.1097/00002371-199102000-00003 |
0.391 |
|
1991 |
Pak CC, Fidler IJ. Liposomal delivery of biological response modifiers to macrophages Biotherapy. 3: 55-64. PMID 2009214 DOI: 10.1007/Bf02175099 |
0.407 |
|
1991 |
O'Brian CA, Fan D, Ward NE, Dong Z, Iwamoto L, Gupta KP, Earnest LE, Fidler IJ. Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma cells in vitro Biochemical Pharmacology. 41: 797-806. PMID 1998534 DOI: 10.1016/0006-2952(91)90083-H |
0.356 |
|
1991 |
Naito S, Kumazawa J, von Eschenbach AC, Fidler IJ. Metastatic heterogeneity of human renal cell carcinoma. Urologia Internationalis. 90-5. PMID 1949389 DOI: 10.1159/000282262 |
0.34 |
|
1991 |
Nii A, Utsugi T, Fan D, Denkins Y, Pak C, Brown D, van Hoogevest P, Fidler IJ. Optimization of the liposomes encapsulating a new lipopeptide CGP 31362 for efficient activation of tumoricidal properties in monocytes and macrophages. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 10: 236-46. PMID 1931862 DOI: 10.1097/00002371-199108000-00002 |
0.337 |
|
1991 |
Utsugi T, Dinney CP, Killion JJ, Fidler IJ. In situ activation of mouse macrophages and therapy of spontaneous renal cell cancer metastasis by liposomes containing the lipopeptide CGP 31362. Cancer Immunology, Immunotherapy : Cii. 33: 375-81. PMID 1878891 DOI: 10.1007/Bf01741597 |
0.4 |
|
1991 |
Utsugi T, Nii A, Fan D, Pak CC, Denkins Y, van Hoogevest P, Fidler IJ. Comparative efficacy of liposomes containing synthetic bacterial cell wall analogues for tumoricidal activation of monocytes and macrophages. Cancer Immunology, Immunotherapy : Cii. 33: 285-92. PMID 1868486 DOI: 10.1007/Bf01756592 |
0.333 |
|
1991 |
Fidler IJ. Cancer metastasis. British Medical Bulletin. 47: 157-77. PMID 1863845 DOI: 10.1093/oxfordjournals.bmb.a072453 |
0.311 |
|
1991 |
Saiki I, Naito S, Yoneda J, Azuma I, Price JE, Fidler IJ. Characterization of the invasive and metastatic phenotype in human renal cell carcinoma. Clinical & Experimental Metastasis. 9: 551-66. PMID 1752085 DOI: 10.1007/Bf01768583 |
0.435 |
|
1990 |
Frangos DN, Killion JJ, Fan D, Fishbeck R, von Eschenbach AC, Fidler IJ. The development of liposomes containing interferon alpha for the intravesical therapy of human superficial bladder cancer. The Journal of Urology. 143: 1252-6. PMID 2342197 DOI: 10.1016/S0022-5347(17)40248-5 |
0.34 |
|
1990 |
Fidler IJ, Radinsky R. Genetic control of cancer metastasis. Journal of the National Cancer Institute. 82: 166-8. PMID 2296042 DOI: 10.1093/Jnci/82.3.166 |
0.373 |
|
1990 |
Whitworth PW, Pak CC, Esgro J, Kleinerman ES, Fidler IJ. Macrophages and cancer. Cancer Metastasis Reviews. 8: 319-51. PMID 2182211 DOI: 10.1007/Bf00052607 |
0.497 |
|
1990 |
Morikawa K, Morikawa R, Killion JJ, Fan D, Fidler IJ. Isolation of human colon carcinoma cells for resistance to a single interferon associated with cross-resistance to multiple recombinant interferons: alpha, beta, and gamma. Journal of the National Cancer Institute. 82: 517-22. PMID 2138228 DOI: 10.1093/Jnci/82.6.517 |
0.318 |
|
1989 |
Pak CC, Fidler IJ. Activated macrophages distinguish undifferentiated-tumorigenic from differentiated-nontumorigenic murine erythroleukemia cells Differentiation. 41: 49-55. PMID 2806772 DOI: 10.1111/J.1432-0436.1989.Tb00731.X |
0.317 |
|
1989 |
Li L, Price JE, Fan D, Zhang Rd, Bucana CD, Fidler IJ. Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites Journal of the National Cancer Institute. 81: 1406-1412. PMID 2778827 DOI: 10.1093/Jnci/81.18.1406 |
0.471 |
|
1989 |
Killion JJ, Fan D, Bucana CD, Frangos DN, Price JE, Fidler IJ. Augmentation of antiproliferative activity of interferon alfa against human bladder tumor cell lines by encapsulation of interferon alfa within liposomes Journal of the National Cancer Institute. 81: 1387-1392. PMID 2778824 DOI: 10.1093/Jnci/81.18.1387 |
0.319 |
|
1989 |
Schackert HK, Fidler IJ. Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases. International Journal of Cancer. 44: 177-81. PMID 2744889 DOI: 10.1002/Ijc.2910440131 |
0.418 |
|
1989 |
Connor J, Bucana C, Fidler IJ, Schroit AJ. Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation. Proceedings of the National Academy of Sciences of the United States of America. 86: 3184-8. PMID 2717615 DOI: 10.1073/Pnas.86.9.3184 |
0.339 |
|
1989 |
Mccready DR, Balch CM, Fidler IJ, Murray JL. Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo Journal of the National Cancer Institute. 81: 682-687. PMID 2709424 DOI: 10.1093/Jnci/81.9.682 |
0.425 |
|
1989 |
O'Brian CA, Fan D, Ward NE, Seid C, Fidler IJ. Level of protein kinase C activity correlates directly with resistance to adriamycin in murine fibrosarcoma cells Febs Letters. 246: 78-82. PMID 2707442 DOI: 10.1016/0014-5793(89)80257-1 |
0.322 |
|
1989 |
Albini A, Aukerman SL, Ogle RC, Noonan DM, Fridman R, Martin GR, Fidler IJ. The in vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants. Clinical & Experimental Metastasis. 7: 437-51. PMID 2706831 DOI: 10.1007/Bf01753664 |
0.39 |
|
1989 |
Naito S, Walker SM, Fidler IJ. In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice. Clinical & Experimental Metastasis. 7: 381-9. PMID 2706827 DOI: 10.1007/Bf01753659 |
0.42 |
|
1989 |
Fidler IJ. Origin and biology of cancer metastasis. Cytometry. 10: 673-80. PMID 2684578 DOI: 10.1002/cyto.990100602 |
0.371 |
|
1989 |
Johnson JW, Nayar R, Killion JJ, von Eschenbach AC, Fidler IJ. Binding of liposomes to human bladder tumor epithelial cell lines: implications for an intravesical drug delivery system for the treatment of bladder cancer. Selective Cancer Therapeutics. 5: 147-55. PMID 2623380 DOI: 10.1089/Sct.1989.5.147 |
0.413 |
|
1989 |
Schackert G, Price JE, Bucana CD, Fidler IJ. Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice International Journal of Cancer. 44: 892-897. PMID 2583868 DOI: 10.1002/Ijc.2910440524 |
0.392 |
|
1989 |
Fan D, Chakrabarty S, Seid C, Bell CW, Schackert H, Morikawa K, Fidler IJ. Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1. Cancer Communications. 1: 117-25. PMID 2561734 DOI: 10.3727/095535489820875327 |
0.374 |
|
1988 |
Hisano G, Fidler IJ. Systemic activation of macrophages by liposome-entrapped muramyl tripeptide in mice pretreated with the chemotherapeutic agent adriamycin. Cancer Immunology, Immunotherapy : Cii. 14: 61-6. PMID 6965228 DOI: 10.1007/Bf00200168 |
0.327 |
|
1988 |
Schackert G, Fidler IJ. Development of in vivo models for studies of brain metastasis. International Journal of Cancer. 41: 589-94. PMID 3356491 DOI: 10.1002/Ijc.2910410419 |
0.479 |
|
1988 |
Fidler IJ. The biology of melanoma metastasis. The Journal of Dermatologic Surgery and Oncology. 14: 875-81. PMID 3294269 DOI: 10.1111/j.1524-4725.1988.tb03591.x |
0.365 |
|
1988 |
Schackert G, Simmons RD, Buzbee TM, Hume DA, Fidler IJ. Macrophage infiltration into experimental brain metastases: Occurrence through an intact blood-brain barrier Journal of the National Cancer Institute. 80: 1027-1034. PMID 3261801 DOI: 10.1093/Jnci/80.13.1027 |
0.35 |
|
1988 |
Price JE, Sauder DN, Fidler IJ. Tumorigenicity and metastatic behavior in nude mice of two human squamous cell carcinoma lines that differ in production of the cytokine ETAF/IL-1 Journal of Investigative Dermatology. 91: 258-262. PMID 3045210 DOI: 10.1111/1523-1747.Ep12470396 |
0.45 |
|
1988 |
Price JE, Naito S, Fidler IJ. Growth in an organ microenvironment as a selective process in metastasis Clinical & Experimental Metastasis. 6: 91-102. PMID 2961497 DOI: 10.1007/BF01580409 |
0.303 |
|
1987 |
Naito S, Giavazzi R, Walker SM, Itoh K, Mayo J, Fidler IJ. Growth and metastatic behavior of human tumor cells implanted into nude and beige nude mice. Clinical & Experimental Metastasis. 5: 135-46. PMID 3594971 DOI: 10.1007/Bf00058059 |
0.43 |
|
1987 |
Fidler IJ, Balch CM. The biology of cancer metastasis and implications for therapy. Current Problems in Surgery. 24: 129-209. PMID 3568753 DOI: 10.1016/0011-3840(87)90002-5 |
0.322 |
|
1987 |
Naito S, Eschenbach ACV, Fidler IJ. Different Growth Pattern and Biologic Behavior of Human Renal Cell Carcinoma Implanted Into Different Organs of Nude Mice Journal of the National Cancer Institute. 78: 377-385. DOI: 10.1093/Jnci/78.2.377 |
0.443 |
|
1987 |
Brande MC, Algood CB, Wishnow KI, Fidler IJ. Invasion of Organ-Cultured Urinary Bladder by Spheroid-Derived Tumor CellS Journal of Urology. 137. DOI: 10.1016/S0022-5347(17)76087-9 |
0.393 |
|
1986 |
Nayar R, Fidler IJ. The systemic activation of macrophages by liposomes containing immunomodulators. Springer Seminars in Immunopathology. 8: 413-28. PMID 4089759 DOI: 10.1007/Bf01857394 |
0.33 |
|
1986 |
Aukerman SL, Siciliano MJ, Fidler IJ. Heterogeneity of isozyme expression in tumor cells does not correlate with metastatic potential. Clinical & Experimental Metastasis. 4: 177-89. PMID 3742891 DOI: 10.1007/Bf00117931 |
0.464 |
|
1986 |
Saiki I, Nayar R, Bucana C, Fidler IJ. A microassay for the rapid and selective binding of cells from solid tumors to mouse macrophages. Cancer Immunology, Immunotherapy : Cii. 22: 125-31. PMID 3719592 DOI: 10.1007/BF00199126 |
0.334 |
|
1986 |
Frost P, Fidler IJ. Biology of metastasis. Cancer. 58: 550-3. PMID 3719550 DOI: 10.1002/1097-0142(19860715)58:2+<550::Aid-Cncr2820581324>3.0.Co;2-Z |
0.442 |
|
1986 |
Fidler IJ. Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis. Cancer Metastasis Reviews. 5: 29-49. PMID 2942306 DOI: 10.1007/Bf00049529 |
0.483 |
|
1986 |
Giavazzi R, Jessup JM, Campbell DE, Walker SM, Fidler IJ. Experimental Nude Mouse Model of Human Colorectal Cancer Liver Metastases Journal of the National Cancer Institute. 77: 1303-1308. DOI: 10.1093/Jnci/77.6.1303 |
0.355 |
|
1986 |
Aukerman SL, Price JE, Fidler IJ. Different deficiencies in the prevention of tumorigenic-low-metastatic murine K-1735b melanoma cells from producing metastases. Journal of the National Cancer Institute. 77: 915-924. DOI: 10.1093/Jnci/77.4.915 |
0.463 |
|
1986 |
Nicolson GL, Fidler IJ, Poste G. Effects of Tertiary Amine Local Anesthetics on the Blood-Borne Implantation and Cell Surface Properties of Metastatic Mouse Melanoma Cells Journal of the National Cancer Institute. 76: 511-519. DOI: 10.1093/Jnci/76.3.511 |
0.45 |
|
1985 |
Xu Z, Fidler IJ. The in situ activation of cytotoxic properties in murine Kupffer cells by the systemic administration of whole Mycobacterium bovis organisms or muramyl tripeptide. Cancer Immunology, Immunotherapy : Cii. 18: 118-22. PMID 6391654 DOI: 10.1007/Bf00205745 |
0.444 |
|
1985 |
Schroit AJ, Tanaka Y, Madsen J, Fidler IJ. The recognition of red blood cells by macrophages: role of phosphatidylserine and possible implications of membrane phospholipid asymmetry. Biology of the Cell. 51: 227-38. PMID 6240306 DOI: 10.1111/J.1768-322X.1984.Tb00303.X |
0.302 |
|
1985 |
Kleinerman ES, Wiltrout RH, Zicht R, Fidler IJ. Human lymphokine preparations which generate tumoricidal properties of human monocytes in vitro may be distinct from gamma interferon. Cancer Immunology, Immunotherapy : Cii. 20: 151-7. PMID 3930068 DOI: 10.1007/Bf00205682 |
0.317 |
|
1985 |
Koff WC, Fogler WE, Gutterman J, Fidler IJ. Efficient activation of human blood monocytes to a tumoricidal state by liposomes containing human recombinant gamma interferon. Cancer Immunology, Immunotherapy : Cii. 19: 85-9. PMID 3921232 DOI: 10.1007/Bf00199714 |
0.327 |
|
1985 |
Kleinerman ES, Fogler WE, Fidler IJ. Intracellular activation of human and rodent macrophages by human lymphokines encapsulated in liposomes. Journal of Leukocyte Biology. 37: 571-84. PMID 3920339 DOI: 10.1002/Jlb.37.5.571 |
0.351 |
|
1984 |
Fidler IJ, Burger MM. UICC Study Group in basic and clinical cancer research: cancer metastasis. International Journal of Cancer. Journal International Du Cancer. 33: 1-3. PMID 6693188 DOI: 10.1002/Ijc.2910330102 |
0.301 |
|
1984 |
Koff WC, Fidler IJ, Showalter SD, Chakrabarty MK, Hampar B, Ceccorulli LM, Kleinerman ES. Human monocytes activated by immunomodulators in liposomes lyse herpesvirus-infected but not normal cells. Science (New York, N.Y.). 224: 1007-9. PMID 6426057 DOI: 10.1126/Science.6426057 |
0.336 |
|
1984 |
Fidler IJ, Kleinerman ES. Lymphokine-activated human blood monocytes destroy tumor cells but not normal cells under cocultivation conditions. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 2: 937-43. PMID 6379124 DOI: 10.1200/Jco.1984.2.8.937 |
0.388 |
|
1984 |
Fidler IJ, Kozlowski JM. The heterogeneous nature of metastatic neoplasms: implications for the treatment of cancer. Urology. 23: 29-38. PMID 6369719 DOI: 10.1016/S0090-4295(84)80064-3 |
0.455 |
|
1984 |
Kozlowski JM, Hart IR, Fidler IJ, Hanna N. A Human Melanoma Line Heterogeneous With Respect to Metastatic Capacity in Athymic Nude Mice Journal of the National Cancer Institute. 72: 913-917. DOI: 10.1093/Jnci/72.4.913 |
0.407 |
|
1983 |
Fidler IJ, Poste G. Macrophages and cancer metastasis. Advances in Experimental Medicine and Biology. 155: 65-75. PMID 6984285 DOI: 10.1007/978-1-4684-4394-3_5 |
0.445 |
|
1983 |
Fidler IJ, Poste G. Macrophage-mediated destruction of malignant tumor cells and new strategies for the therapy of metastatic disease. Springer Seminars in Immunopathology. 5: 161-74. PMID 6755782 DOI: 10.1007/Bf00199794 |
0.407 |
|
1983 |
Thistlethwaithe P, Davidson DD, Fidler IJ, Roth JA. Syngeneic humoral immune responses to tumor-associated antigens expressed by K-1735 UV-induced melanoma and its metastases. Cancer Immunology, Immunotherapy : Cii. 15: 11-6. PMID 6553502 DOI: 10.1007/Bf00199455 |
0.36 |
|
1982 |
Hanna N, Davis TW, Fidler IJ. Environmental and genetic factors determine the level of NK activity of nude mice and affect their suitability as models for experimental metastasis. International Journal of Cancer. 30: 371-6. PMID 7129682 DOI: 10.1002/Ijc.2910300319 |
0.382 |
|
1982 |
Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science (New York, N.Y.). 217: 998-1003. PMID 7112116 DOI: 10.1126/Science.7112116 |
0.424 |
|
1982 |
Cifone MA, Fidler IJ. Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proceedings of the National Academy of Sciences of the United States of America. 78: 6949-52. PMID 6947269 DOI: 10.1073/Pnas.78.11.6949 |
0.413 |
|
1982 |
Fidler IJ, Poste G. The biologic diversity of cancer metastases. Hospital Practice (Office Ed.). 17: 57-64. PMID 6809572 DOI: 10.1080/21548331.1982.11698073 |
0.375 |
|
1982 |
Fidler IJ, Hart IR. The origin of metastatic heterogeneity in tumors. European Journal of Cancer. 17: 487-94. PMID 6271554 DOI: 10.1016/0014-2964(81)90049-9 |
0.449 |
|
1982 |
Talmadge JE, Fidler IJ. Enhanced Metastatic Potential of Tumor Cells Harvested From Spontaneous Metastases of Heterogeneous Murine Tumors Journal of the National Cancer Institute. 69: 975-980. DOI: 10.1093/Jnci/69.4.975 |
0.459 |
|
1982 |
Pollack VA, Fidler IJ. Use of Young Nude Mice for Selection of Subpopulations of Cells With Increased Metastatic Potential From Nonsyngeneic Neoplasms Journal of the National Cancer Institute. 69: 137-141. DOI: 10.1093/Jnci/69.1.137 |
0.441 |
|
1982 |
Sone S, Fidler I. In situ activation of tumoricidal properties in rat alveolar macrophages and rejection of experimental lung metastases by intravenous injections of Nocardia rubra cell wall skeleton Cancer Immunology Immunotherapy. 12. DOI: 10.1007/Bf00199175 |
0.332 |
|
1981 |
Sone S, Fidler IJ. In vitro activation of tumoricidal properties in rat alveolar macrophages by synthetic muramyl dipeptide encapsulated in liposomes. Cellular Immunology. 57: 42-50. PMID 7214534 DOI: 10.1016/0008-8749(81)90118-0 |
0.359 |
|
1981 |
Hart IR, Fidler IJ. The implications of tumor heterogeneity for studies on the biology of cancer metastasis. Biochimica Et Biophysica Acta. 651: 37-50. PMID 7025905 DOI: 10.1016/0304-419X(81)90004-4 |
0.422 |
|
1981 |
Poste G, Doll J, Fidler IJ. Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells Proceedings of the National Academy of Sciences of the United States of America. 78: 6226-6230. PMID 6947225 DOI: 10.1073/Pnas.78.10.6226 |
0.31 |
|
1981 |
Fidler IJ, Sone S, Fogler WE, Barnes ZL. Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proceedings of the National Academy of Sciences of the United States of America. 78: 1680-4. PMID 6940181 DOI: 10.1073/Pnas.78.3.1680 |
0.396 |
|
1981 |
Raz A, Hanna N, Fidler IJ. In vivo isolation of a metastatic tumor cell variant involving selective and nonadaptive processes12 3 Journal of the National Cancer Institute. 66: 183-189. PMID 6935459 DOI: 10.1093/Jnci/66.1.183 |
0.446 |
|
1981 |
Hanna N, Fidler IJ. Relationship Between Metastatic Potential and Resistance to Natural Killer Cellmediated Cytotoxicity in Three Murine Tumor Systems Journal of the National Cancer Institute. 66: 1183-1190. DOI: 10.1093/Jnci/66.6.1183 |
0.35 |
|
1981 |
Hart IR, Fogler WE, Poste G, Fidler IJ. Toxicity studies of liposome-encapsulated immunomodulators administered intravenously to dogs and mice Cancer Immunology, Immunotherapy. 10: 157-166. DOI: 10.1007/Bf00205887 |
0.369 |
|
1981 |
Fidler I, Davis T, Raz A. The influence of host health and environment on natural cytotoxicity of mouse macrophages Cancer Immunology Immunotherapy. 11. DOI: 10.1007/Bf00199490 |
0.366 |
|
1980 |
Fogler WE, Raz A, Fidler IJ. In situ activation of murine macrophages by liposomes containing lymphokines. Cellular Immunology. 53: 214-9. PMID 7407932 DOI: 10.1016/0008-8749(80)90440-2 |
0.348 |
|
1980 |
Fidler IJ. Therapy of spontaneous metastases by intravenous injection of liposomes containing lymphokines. Science (New York, N.Y.). 208: 1469-71. PMID 7384789 DOI: 10.1126/Science.7384789 |
0.363 |
|
1980 |
Raz A, Bucana C, McLellan W, Fidler IJ. Distribution of membrane anionic sites on B16 melanoma variants with differing lung colonising potential Nature. 284: 363-364. PMID 7360272 DOI: 10.1038/284363A0 |
0.347 |
|
1980 |
Poste G, Fidler IJ. The pathogenesis of cancer metastasis. Nature. 283: 139-46. PMID 6985715 DOI: 10.1038/283139A0 |
0.421 |
|
1980 |
Hanna N, Fidler IJ. Role of natural killer cells in the destruction of circulating tumor emboli. Journal of the National Cancer Institute. 65: 801-9. PMID 6932529 DOI: 10.1093/Jnci/65.4.801 |
0.476 |
|
1980 |
Cifone MA, Fidler IJ. Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 77: 1039-43. PMID 6928659 DOI: 10.1073/Pnas.77.2.1039 |
0.483 |
|
1980 |
Hart IR, Fidler IJ. Cancer invasion and metastasis. The Quarterly Review of Biology. 55: 121-42. PMID 6251508 DOI: 10.1016/B978-0-12-386456-7.01910-9 |
0.486 |
|
1980 |
Fidler IJ, Fogler WE, Barnes Z, Fisher K. The treatment of established micrometastases with syngeneic macrophages. Advances in Experimental Medicine and Biology. 399-410. PMID 397756 DOI: 10.1007/978-1-4684-8914-9_37 |
0.407 |
|
1980 |
Hart IR, Raz A, Fidler IJ. Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells Journal of the National Cancer Institute. 64: 891-900. DOI: 10.1093/Jnci/64.4.891 |
0.454 |
|
1980 |
Fidler IJ, Kripke ML. Tumor cell antigenicity, host immunity, and cancer metastasis Cancer Immunology Immunotherapy. 7: 201-205. DOI: 10.1007/Bf00205466 |
0.412 |
|
1979 |
Cifone MA, Kripke ML, Fidler IJ. Growth rate and chromosome number of tumor cell lines with different metastatic potential Journal of Supramolecular and Cellular Biochemistry. 11: 467-476. PMID 544925 DOI: 10.1002/Jss.400110405 |
0.391 |
|
1979 |
Poste G, Kirsh R, Fidler IJ. Cell surface receptors for lymphokines. I. The possible role of glycolipids as receptors for macrophage migration inhibitory factor (MIF) and macrophage activation factor (MAF). Cellular Immunology. 44: 71-88. PMID 378418 DOI: 10.1016/0008-8749(79)90029-7 |
0.313 |
|
1979 |
Raz A, Fogler W, Fidler I. The effects of experimental conditions on the expression of in vitro-mediated tumor cytotoxicity mediated by murine macrophages Cancer Immunology Immunotherapy. 7. DOI: 10.1007/Bf00199193 |
0.419 |
|
1978 |
Fidler IJ, Gersten DM, Hart IR. The biology of cancer invasion and metastasis. Advances in Cancer Research. 28: 149-250. PMID 360795 DOI: 10.1016/S0065-230X(08)60648-X |
0.497 |
|
1978 |
Fidler IJ, Roblin RO, Poste G. In vitro tumoricidal activity of macrophages against virus-transformed lines with temperature-dependent transformed phenotypic characteristics. Cellular Immunology. 38: 131-46. PMID 208781 DOI: 10.1016/0008-8749(78)90039-4 |
0.308 |
|
1977 |
Fidler IJ, Nicolson GL. Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. Journal of the National Cancer Institute. 57: 1199-202. PMID 1003551 DOI: 10.1093/Jnci/57.5.1199 |
0.431 |
|
1977 |
Gersten DM, Fogler WE, Fidler IJ. Quantitative analysis of macrophage phagocytosis by uptake of particulate 192iridium. Journal of Immunological Methods. 17: 349-59. PMID 915303 DOI: 10.1016/0022-1759(77)90117-X |
0.3 |
|
1977 |
Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor Science. 197: 893-895. PMID 887927 DOI: 10.1126/Science.887927 |
0.428 |
|
1977 |
Fidler IJ, Gersten DM, Riggs CW. Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis. Cancer. 40: 46-55. PMID 880570 DOI: 10.1002/1097-0142(197707)40:1<46::Aid-Cncr2820400110>3.0.Co;2-T |
0.434 |
|
1977 |
Fidler IJ, Nicolson GL. Fate of recirculating B16 melanoma metastatic variant cells in parabiotic syngeneic recipients. Journal of the National Cancer Institute. 58: 1867-72. PMID 864765 DOI: 10.1093/Jnci/58.6.1867 |
0.344 |
|
1977 |
Kripke ML, Budmen MB, Fidler IJ. Production of specific macrophage activating factor by lymphocytes from tumor-bearing mice Cellular Immunology. 30: 341-352. PMID 67910 DOI: 10.1016/0008-8749(77)90077-6 |
0.437 |
|
1977 |
NICOLSON GL, BRUNSON KW, FIDLER IJ. TUMOR CELL SURFACES: SOME CHARACTERISTICS OF NEOPLASTIC CELLS THAT DETERMINE STATES OF TRANSFORMATION AND MALIGNANCY Acta Histochemica Et Cytochemica. 10: 114-133. DOI: 10.1267/Ahc.10.114 |
0.459 |
|
1976 |
Fidler IJ. Activation in vitro of mouse macrophages by syngeneic, allogeneic, or xenogeneic lymphocyte supernatants. Journal of the National Cancer Institute. 55: 1159-63. PMID 1206741 DOI: 10.1093/Jnci/55.5.1159 |
0.425 |
|
1976 |
Fidler IJ, Spitler LE. Effects of levamisole on in vivo and in vitro murine host response to syngeneic transplantable tumor. Journal of the National Cancer Institute. 55: 1107-12. PMID 1206735 DOI: 10.1093/Jnci/55.5.1107 |
0.446 |
|
1976 |
Fidler IJ, McWilliams RW, Bech-Nielsen S, Budmen MB. Role of the regional lymph node in neoplasia: cellular mediated reactivity in vitro by autologous regional or distant lymph nodes or peripheral blood lymphocytes of dogs with spontaneous neoplasms. Immunological Communications. 4: 325-35. PMID 1184114 DOI: 10.3109/08820137509055783 |
0.385 |
|
1976 |
Fidler IJ, Caines S, Dolan Z. Survival of hematogenously disseminated allogeneic tumor cells in athymic nude mice. Transplantation. 22: 208-12. PMID 968936 DOI: 10.1097/00007890-197608000-00019 |
0.314 |
|
1976 |
Fidler IJ, Budmen MB, Hanna MG. Characterization of in vitro reactivity by BCG-treated guinea pigs to syngeneic line-10 hepatocarcinoma Cancer Immunology, Immunotherapy. 1: 179-186. DOI: 10.1007/Bf00205463 |
0.409 |
|
1975 |
Norbury KC, Fidler IJ. In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity. Journal of Immunological Methods. 7: 109-22. PMID 1123549 DOI: 10.1016/0022-1759(75)90136-2 |
0.319 |
|
1974 |
Fidler IJ. The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. European Journal of Cancer. 9: 223-7. PMID 4787857 DOI: 10.1016/S0014-2964(73)80022-2 |
0.444 |
|
1974 |
Fidler IJ. Immunostimulation-inhibition of tumor cell growth in vitro utilizing tumor target cells labeled with 125I-iodo-deoxyuridine. Immunological Communications. 2: 483-93. PMID 4757433 DOI: 10.3109/08820137309022820 |
0.426 |
|
1973 |
Fidler IJ. In vitro studies of cellular-mediated immunostimulation of tumor growth. Journal of the National Cancer Institute. 50: 1307-12. PMID 4712593 DOI: 10.1093/Jnci/50.5.1307 |
0.398 |
|
1973 |
Fidler IJ. Selection of successive tumour lines for metastasis. Nature: New Biology. 242: 148-9. PMID 4512654 DOI: 10.1038/Newbio242148A0 |
0.384 |
|
1973 |
Fidler IJ, Kahn JM, Montgomery PC. Effect of neuraminidase on the rat one-way mixed lymphocyte interaction. Immunological Communications. 2: 573-83. PMID 4272634 DOI: 10.3109/08820137309022828 |
0.301 |
|
1971 |
Fidler IJ. Duration of in vivo effects of L-asparaginase on experimental metastasis. Nature. 229: 564-564. PMID 4925355 DOI: 10.1038/229564A0 |
0.31 |
|
1970 |
Fidler IJ. Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With 125I-5-Iodo-2′ -deoxyuridine Journal of the National Cancer Institute. 45: 773-782. DOI: 10.1093/Jnci/45.4.773 |
0.345 |
|
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