| Year |
Citation |
Score |
| 2021 |
Brzezinska P, Simpson NJ, Hubert F, Jacobs AN, Umana MB, MacKeil JL, Burke-Kleinman J, Payne DM, Ferguson AV, Maurice DH. Phosphodiesterase 1C integrates store-operated calcium entry and cAMP signaling in leading-edge protrusions of migrating human arterial myocytes. The Journal of Biological Chemistry. 100606. PMID 33789162 DOI: 10.1016/j.jbc.2021.100606 |
0.304 |
|
| 2020 |
Burke-Kleinman J, Maurice DH. Phosphodiesterase 4D7 selectively regulates cAMP-mediated control of human arterial endothelial cell transcriptomic responses to fluid shear stress. Canadian Journal of Physiology and Pharmacology. 1-6. PMID 32846105 DOI: 10.1139/Cjpp-2020-0318 |
0.452 |
|
| 2019 |
Brzezinska P, Maurice DH. An EPAC1/PDE1C-Signaling Axis Regulates Formation of Leading-Edge Protrusion in Polarized Human Arterial Vascular Smooth Muscle Cells Cells. 8: 1473. PMID 31757003 DOI: 10.3390/Cells8121473 |
0.474 |
|
| 2019 |
MacKeil JL, Brzezinska P, Burke-Kleinman J, Theilmann AL, Nicol CJB, Ormiston ML, Maurice DH. Phosphodiesterase 3B (PDE3B) antagonizes the anti-angiogenic actions of PKA in human and murine endothelial cells. Cellular Signalling. 62: 109342. PMID 31176020 DOI: 10.1016/J.Cellsig.2019.06.007 |
0.516 |
|
| 2019 |
MacKeil JL, Brzezinska P, Burke-Kleinman J, Craig AW, Nicol CJB, Maurice DH. A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling Scientific Reports. 9: 1-15. PMID 30787359 DOI: 10.1038/S41598-018-37805-Y |
0.511 |
|
| 2017 |
Wilson LS, Guo M, Bibiana Umana M, Maurice DH. Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells. Cellular Signalling. PMID 28506928 DOI: 10.1016/j.cellsig.2017.04.019 |
0.401 |
|
| 2017 |
Selvam SN, Casey LJ, Bowman ML, Hawke LG, Longmore AJ, Mewburn J, Ormiston ML, Archer SL, Maurice DH, James P. Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. PMID 28362648 DOI: 10.1097/Mbc.0000000000000635 |
0.384 |
|
| 2016 |
Rampersad SN, Freitag SI, Hubert F, Brzezinska P, Butler N, Umana MB, Wudwud AR, Maurice DH. EPAC1 promotes adaptive responses in human arterial endothelial cells subjected to low levels of laminar fluid shear stress: Implications in flow-related endothelial dysfunction. Cellular Signalling. 28: 606-19. PMID 26979996 DOI: 10.1016/j.cellsig.2016.02.016 |
0.306 |
|
| 2016 |
Rampersad SN, Wudwud A, Hubert F, Maurice DH. Adaptive phenotypic modulation of human arterial endothelial cells to fluid shear stress-encoded signals: modulation by phosphodiesterase 4D-VE-cadherin signalling. Cellular Signalling. 28: 741-8. PMID 26658094 DOI: 10.1016/j.cellsig.2015.12.001 |
0.339 |
|
| 2015 |
Ahmad F, Murata T, Shimizu K, Degerman E, Maurice D, Manganiello V. Cyclic nucleotide phosphodiesterases: Important signaling modulators and therapeutic targets Oral Diseases. 21: e25-e50. DOI: 10.1111/Odi.12275 |
0.42 |
|
| 2014 |
Giembycz MA, Maurice DH. Cyclic nucleotide-based therapeutics for chronic obstructive pulmonary disease. Current Opinion in Pharmacology. 16: 89-107. PMID 24810285 DOI: 10.1016/J.Coph.2014.04.001 |
0.356 |
|
| 2014 |
Maurice DH, Wilson LS, Rampersad SN, Hubert F, Truong T, Kaczmarek M, Brzezinska P, Freitag SI, Umana MB, Wudwud A. Cyclic nucleotide phosphodiesterases (PDEs): coincidence detectors acting to spatially and temporally integrate cyclic nucleotide and non-cyclic nucleotide signals. Biochemical Society Transactions. 42: 250-6. PMID 24646226 DOI: 10.1042/Bst20130268 |
0.398 |
|
| 2013 |
Lee LC, Maurice DH, Baillie GS. Targeting protein-protein interactions within the cyclic AMP signaling system as a therapeutic strategy for cardiovascular disease. Future Medicinal Chemistry. 5: 451-64. PMID 23495691 DOI: 10.4155/Fmc.12.216 |
0.405 |
|
| 2013 |
Hamilton TK, Hu N, Kolomitro K, Bell EN, Maurice DH, Graham CH, Siemens DR. Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer. World Journal of Urology. 31: 325-30. PMID 22383129 DOI: 10.1007/S00345-012-0848-7 |
0.322 |
|
| 2011 |
Maurice DH. Subcellular signaling in the endothelium: cyclic nucleotides take their place. Current Opinion in Pharmacology. 11: 656-64. PMID 22036169 DOI: 10.1016/J.Coph.2011.10.009 |
0.467 |
|
| 2011 |
Beca S, Helli PB, Simpson JA, Zhao D, Farman GP, Jones PP, Tian X, Wilson LS, Ahmad F, Chen SR, Movsesian MA, Manganiello V, Maurice DH, Conti M, Backx PH. Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current. Circulation Research. 109: 1024-30. PMID 21903937 DOI: 10.1161/Circresaha.111.250464 |
0.316 |
|
| 2011 |
Wilson LS, Baillie GS, Pritchard LM, Umana B, Terrin A, Zaccolo M, Houslay MD, Maurice DH. A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells. The Journal of Biological Chemistry. 286: 16285-96. PMID 21393242 DOI: 10.1074/jbc.M110.217026 |
0.411 |
|
| 2010 |
Rampersad SN, Ovens JD, Huston E, Umana MB, Wilson LS, Netherton SJ, Lynch MJ, Baillie GS, Houslay MD, Maurice DH. Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability. The Journal of Biological Chemistry. 285: 33614-22. PMID 20732872 DOI: 10.1074/jbc.M110.140004 |
0.384 |
|
| 2009 |
Raymond DR, Carter RL, Ward CA, Maurice DH. Distinct phosphodiesterase-4D variants integrate into protein kinase A-based signaling complexes in cardiac and vascular myocytes American Journal of Physiology - Heart and Circulatory Physiology. 296: H263-H271. PMID 19060129 DOI: 10.1152/Ajpheart.00425.2008 |
0.467 |
|
| 2008 |
Wilson LS, Elbatarny HS, Crawley SW, Bennett BM, Maurice DH. Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions. Proceedings of the National Academy of Sciences of the United States of America. 105: 13650-5. PMID 18757735 DOI: 10.1073/Pnas.0804738105 |
0.456 |
|
| 2007 |
Raymond DR, Wilson LS, Carter RL, Maurice DH. Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion Cellular Signalling. 19: 2507-2518. PMID 17884339 DOI: 10.1016/J.Cellsig.2007.08.005 |
0.429 |
|
| 2007 |
Netherton SJ, Sutton JA, Wilson LS, Carter RL, Maurice DH. Both protein kinase A and exchange protein activated by cAMP coordinate adhesion of human vascular endothelial cells. Circulation Research. 101: 768-76. PMID 17717302 DOI: 10.1161/Circresaha.106.146159 |
0.472 |
|
| 2007 |
Furmaniak-Kazmierczak E, Crawley SW, Carter RL, Maurice DH, Côté GP. Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells Circulation Research. 100: 1328-1336. PMID 17446433 DOI: 10.1161/Circresaha.106.147744 |
0.39 |
|
| 2007 |
Houslay MD, Baillie GS, Maurice DH. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circulation Research. 100: 950-66. PMID 17431197 DOI: 10.1161/01.Res.0000261934.56938.38 |
0.491 |
|
| 2007 |
Palmer D, Jimmo SL, Raymond DR, Wilson LS, Carter RL, Maurice DH. Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation Journal of Biological Chemistry. 282: 9411-9419. PMID 17255105 DOI: 10.1074/Jbc.M606936200 |
0.424 |
|
| 2007 |
Elbatarny HS, Netherton SJ, Ovens JD, Ferguson AV, Maurice DH. Adiponectin, ghrelin, and leptin differentially influence human platelet and human vascular endothelial cell functions: implication in obesity-associated cardiovascular diseases. European Journal of Pharmacology. 558: 7-13. PMID 17207790 DOI: 10.1016/J.Ejphar.2006.11.052 |
0.385 |
|
| 2006 |
MacPherson JD, Gillespie TD, Dunkerley HA, Maurice DH, Bennett BM. Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulation. The Journal of Pharmacology and Experimental Therapeutics. 317: 188-95. PMID 16330494 DOI: 10.1124/Jpet.105.094763 |
0.319 |
|
| 2005 |
Tilley DG, Maurice DH. Vascular smooth muscle cell phenotype-dependent phosphodiesterase 4D short form expression: role of differential histone acetylation on cAMP-regulated function. Molecular Pharmacology. 68: 596-605. PMID 15937214 DOI: 10.1124/Mol.105.014126 |
0.509 |
|
| 2005 |
Elbatarny HS, Maurice DH. Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex. American Journal of Physiology. Endocrinology and Metabolism. 289: E695-702. PMID 15886225 DOI: 10.1152/Ajpendo.00125.2005 |
0.417 |
|
| 2005 |
Maurice DH. Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1221-8. PMID 15769620 DOI: 10.2741/1614 |
0.456 |
|
| 2005 |
Netherton SJ, Maurice DH. Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis. Molecular Pharmacology. 67: 263-72. PMID 15475573 DOI: 10.1124/Mol.104.004853 |
0.479 |
|
| 2004 |
Elbatarny HS, Maurice DH. Leptin-Mediated Activation of Human Platelets: Involvement of a Leptin Receptor and Phosphodiesterase 3A Cellular Signaling Complex. Blood. 104: 3895-3895. DOI: 10.1182/Blood.V104.11.3895.3895 |
0.408 |
|
| 2003 |
Maurice DH, Palmer D, Tilley DG, Dunkerley HA, Netherton SJ, Raymond DR, Elbatarny HS, Jimmo SL. Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system. Molecular Pharmacology. 64: 533-46. PMID 12920188 DOI: 10.1124/Mol.64.3.533 |
0.473 |
|
| 2003 |
Maurice DH. Does sildenafil indirectly inhibit phosphodiesterase 3 in vascular smooth muscle? Hypertension. 41: e2. PMID 12623968 DOI: 10.1161/01.Hyp.0000054979.81019.0A |
0.377 |
|
| 2002 |
Tilley DG, Maurice DH. Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo. Molecular Pharmacology. 62: 497-506. PMID 12181425 DOI: 10.1124/Mol.62.3.497 |
0.435 |
|
| 2002 |
Dunkerley HA, Tilley DG, Palmer D, Liu H, Jimmo SL, Maurice DH. Reduced phosphodiesterase 3 activity and phosphodiesterase 3A level in synthetic vascular smooth muscle cells: implications for use of phosphodiesterase 3 inhibitors in cardiovascular tissues. Molecular Pharmacology. 61: 1033-40. PMID 11961121 DOI: 10.1124/Mol.61.5.1033 |
0.467 |
|
| 2002 |
Netherton SJ, Jimmo SL, Palmer D, Tilley DG, Dunkerley HA, Raymond DR, Russell JC, Absher PM, Sage EH, Vernon RB, Maurice DH. Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease. Diabetes. 51: 1194-200. PMID 11916944 DOI: 10.2337/Diabetes.51.4.1194 |
0.449 |
|
| 2000 |
Palmer D, Maurice DH. Dual expression and differential regulation of phosphodiesterase 3A and phosphodiesterase 3B in human vascular smooth muscle: implications for phosphodiesterase 3 inhibition in human cardiovascular tissues. Molecular Pharmacology. 58: 247-252. PMID 10908291 DOI: 10.1124/Mol.58.2.247 |
0.445 |
|
| 2000 |
Liu H, Palmer D, Jimmo SL, Tilley DG, Dunkerley HA, Pang SC, Maurice DH. Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways. A potential mechanism allowing for the coordinated regulation of PDE4D activity and expression in cells. Journal of Biological Chemistry. 275: 26615-26624. PMID 10851231 DOI: 10.1074/Jbc.M001634200 |
0.503 |
|
| 2000 |
Ribau JCO, Samis JA, Senis YA, Maurice DH, Giles AR, DeReske M, Absher PM, Hatton MWC, Richardson M. Aortic endothelial cell von Willebrand factor content, and circulating plasminogen activator inhibitor-1 are increased, but expression of endothelial leukocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats. Atherosclerosis. 149: 331-342. PMID 10729383 DOI: 10.1016/S0021-9150(99)00344-5 |
0.338 |
|
| 1999 |
Liu H, Maurice DH. Phosphorylation-mediated Activation and Translocation of the Cyclic AMP-specific Phosphodiesterase PDE4D3 by Cyclic AMP-dependent Protein Kinase and Mitogen-activated Protein Kinases A POTENTIAL MECHANISM ALLOWING FOR THE COORDINATED REGULATION OF PDE4D ACTIVITY AND TARGETING Journal of Biological Chemistry. 274: 10557-10565. PMID 10187850 DOI: 10.1074/Jbc.274.15.10557 |
0.456 |
|
| 1998 |
Palmer D, Tsoi K, Maurice DH. Synergistic Inhibition of Vascular Smooth Muscle Cell Migration by Phosphodiesterase 3 and Phosphodiesterase 4 Inhibitors Circulation Research. 82: 852-861. PMID 9576105 DOI: 10.1161/01.Res.82.8.852 |
0.499 |
|
| 1996 |
Senis YA, Richardson M, Tinlin S, Maurice DH, Giles AR. Changes in the pattern of distribution of von Willebrand factor in rat aortic endothelial cells following thrombin generation in vivo. British Journal of Haematology. 93: 195-203. PMID 8611460 DOI: 10.1046/J.1365-2141.1996.4661005.X |
0.318 |
|
| 1995 |
Maurice DH, Senis YA, Liu H, Giles AR, Horn EH. Cell layer-specific expression of cyclic nucleotide phosphodiesterases in rat arteries: Molecular cloning using isolated cell layers from paraformaldehyde-fixed tissues Journal of Pharmacological and Toxicological Methods. 34: 175-185. PMID 8573769 DOI: 10.1016/1056-8719(95)00092-X |
0.311 |
|
| 1994 |
Liu Z, Nakatsu K, Brien JF, Beaton ED, Marks GS, Maurice DH. Selective sequestration of nitric oxide by subcellular components of vascular smooth muscle and platelets: relationship to nitric oxide stimulation of the soluble guanylyl cyclase. Canadian Journal of Physiology and Pharmacology. 71: 938-45. PMID 7910110 DOI: 10.1139/Y93-142 |
0.319 |
|
| 1991 |
Maurice DH, Crankshaw D, Haslam RJ. Synergistic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. European Journal of Pharmacology. 192: 235-242. PMID 1851703 DOI: 10.1016/0014-2999(91)90048-U |
0.352 |
|
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