| Year |
Citation |
Score |
| 2024 |
Chandrasekar AP, Maynes M, Badley AD. Dynamic modulation of the non-canonical NF-κB signaling pathway for HIV shock and kill. Frontiers in Cellular and Infection Microbiology. 14: 1354502. PMID 38505285 DOI: 10.3389/fcimb.2024.1354502 |
0.399 |
|
| 2022 |
Chandrasekar AP, Cummins NW, Natesampillai S, Misra A, Alto A, Laird G, Badley AD. The BCL-2 Inhibitor Venetoclax Augments Immune Effector Function Mediated by Fas Ligand, TRAIL, and Perforin/Granzyme B, Resulting in Reduced Plasma Viremia and Decreased HIV Reservoir Size during Acute HIV Infection in a Humanized Mouse Model. Journal of Virology. 96: e0173022. PMID 36448802 DOI: 10.1128/jvi.01730-22 |
0.515 |
|
| 2022 |
Chandrasekar AP, Badley AD. Prime, shock and kill: BCL-2 inhibition for HIV cure. Frontiers in Immunology. 13: 1033609. PMID 36341439 DOI: 10.3389/fimmu.2022.1033609 |
0.438 |
|
| 2022 |
Wietgrefe SW, Duan L, Anderson J, Marqués G, Sanders M, Cummins NW, Badley AD, Dobrowolski C, Karn J, Pagliuzza A, Chomont N, Sannier G, Dubé M, Kaufmann DE, Zuck P, et al. Detecting Sources of Immune Activation and Viral Rebound in HIV Infection. Journal of Virology. e0088522. PMID 35856674 DOI: 10.1128/jvi.00885-22 |
0.403 |
|
| 2021 |
Cummins NW, Baker J, Chakraborty R, Dean PG, Garcia-Rivera E, Krogman A, Kumar S, Kuzmichev YV, Laird GM, Landay A, Lichterfeld M, Mahmood M, Martinson J, Maynes M, Natesampillai S, ... ... Badley AD, et al. Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo. Eclinicalmedicine. 42: 101225. PMID 34901797 DOI: 10.1016/j.eclinm.2021.101225 |
0.415 |
|
| 2021 |
Alto A, Natesampillai S, Chandrasekar AP, Krogman A, Misra A, Shweta FNU, VanLith C, Yao JD, Cummins NW, Badley AD. The combination of venetoclax and ixazomib selectively and efficiently kills HIV infected cell lines, but has unacceptable toxicity in primary cell models. Journal of Virology. PMID 33827940 DOI: 10.1128/JVI.00138-21 |
0.483 |
|
| 2020 |
French AJ, Natesampillai S, Krogman A, Correia C, Peterson KL, Alto A, Chandrasekar AP, Misra A, Li Y, Kaufmann SH, Badley AD, Cummins NW. Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. Plos Pathogens. 16: e1008906. PMID 33075109 DOI: 10.1371/journal.ppat.1008906 |
0.527 |
|
| 2019 |
Chandrasekar AP, Cummins NW, Badley AD. The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence. Clinical Microbiology Reviews. 33. PMID 31666279 DOI: 10.1128/CMR.00107-19 |
0.44 |
|
| 2019 |
Paim AC, Badley AD, Cummins NW. Mechanisms of HIV-associated lymphocyte regulated cell death. Aids Research and Human Retroviruses. PMID 31659912 DOI: 10.1089/AID.2019.0213 |
0.504 |
|
| 2019 |
Natesampillai S, Paim AC, Cummins NW, Chandrasekar AP, Bren GD, Lewin SR, Kiem HP, Badley AD. TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31189571 DOI: 10.4049/jimmunol.1900271 |
0.501 |
|
| 2019 |
Paim AC, Cummins NW, Natesampillai S, Garcia-Rivera E, Kogan N, Neogi U, Sönnerborg A, Sperk M, Bren GD, Deeks S, Polley E, Badley AD. HIV elite control is associated with reduced TRAILshort expression. Aids (London, England). PMID 31149947 DOI: 10.1097/Qad.0000000000002279 |
0.514 |
|
| 2018 |
Aboulnasr F, Paranjape G, Badley AD. The TRAIL: TRAILshort Axis in HIV Immunopathology. Critical Reviews in Immunology. 38: 491-503. PMID 31002603 DOI: 10.1615/CritRevImmunol.2019029632 |
0.523 |
|
| 2018 |
Nie Z, Aboulnasr F, Natesampillai S, Burke SP, Krogman A, Bren GD, Chung TDY, Anderson JR, Smart MK, Katzmann DJ, Rajagopalan G, Cummins NW, Badley AD. Correction: Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment. Journal of Immunology (Baltimore, Md. : 1950). PMID 30006376 DOI: 10.4049/Jimmunol.1800867 |
0.405 |
|
| 2018 |
Paim AC, Rizza SA, Badley AD, Prieto M, Taler SJ, Chong PP, Cummins NW. Transient loss of HIV-1 DNA in an HIV-1 positive patient after kidney transplantation: A case report. The American Journal of Medicine. PMID 29730357 DOI: 10.1016/j.amjmed.2018.04.022 |
0.341 |
|
| 2018 |
Natesampillai S, Cummins NW, Nie Z, Sampath R, Baker JV, Henry K, Pinzone M, O'Doherty U, Polley EC, Bren GD, Katzmann DJ, Badley AD. The proapoptotic, HIV protease generated Casp8p41 when bound and inactivated by Bcl2, is degraded by the proteasome. Journal of Virology. PMID 29643240 DOI: 10.1128/Jvi.00037-18 |
0.495 |
|
| 2017 |
Nie Z, Aboulnasr F, Natesampillai S, Burke SP, Krogman A, Bren GD, Chung TDY, Anderson JR, Smart MK, Katzmann DJ, Rajagopalan G, Cummins NW, Badley AD. Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment. Journal of Immunology (Baltimore, Md. : 1950). PMID 29263214 DOI: 10.4049/Jimmunol.1701113 |
0.489 |
|
| 2017 |
Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, ... ... Badley AD, et al. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study. Plos Medicine. 14: e1002461. PMID 29182633 DOI: 10.1371/Journal.Pmed.1002461 |
0.398 |
|
| 2017 |
Sampath R, Cummins NW, Natesampillai S, Bren GD, Chung TD, Baker J, Henry K, Pagliuzza A, Badley AD. Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells. Plos One. 12: e0179327. PMID 28628632 DOI: 10.1371/journal.pone.0179327 |
0.473 |
|
| 2017 |
Cummins NW, Sainski-Nguyen AM, Natesampillai S, Aboulnasr F, Kaufmann S, Badley AD. Maintenance of the HIV reservoir is antagonized by selective BCL2 inhibition. Journal of Virology. PMID 28331083 DOI: 10.1128/Jvi.00012-17 |
0.473 |
|
| 2016 |
Sampath R, Cummins NW, Badley AD. Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV. Journal of Cell Death. 9: 9-17. PMID 27721655 DOI: 10.4137/JCD.S39872 |
0.505 |
|
| 2016 |
Cummins NW, Badley AD, Kasten MJ, Sampath R, Temesgen Z, Whitaker JA, Wilson JW, Yao JD, Zeuli J, Rizza SA. Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present and future. World Journal of Virology. 5: 63-7. PMID 27175350 DOI: 10.5501/wjv.v5.i2.63 |
0.333 |
|
| 2016 |
Cummins NW, Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, de Araujo Correia MC, Sampath R, Rizza SA, O'Brien D, Yao JD, Kaufmann SH, Badley AD. Prime, shock, and kill: Priming CD4 T cells from HIV patients with a BCL-2 antagonist before HIV reactivation reduces HIV reservoir size. Journal of Virology. PMID 26842479 DOI: 10.1128/Jvi.03179-15 |
0.485 |
|
| 2015 |
Cummins NW, Badley AD. Casp8p41 and HIV. Oncotarget. 6: 23042-3. PMID 26309081 DOI: 10.18632/oncotarget.5238 |
0.381 |
|
| 2015 |
Cummins NW, Badley AD. Can HIV Be Cured and Should We Try? Mayo Clinic Proceedings. 90: 705-9. PMID 25944260 DOI: 10.1016/j.mayocp.2015.03.008 |
0.382 |
|
| 2014 |
Cummins NW, Sainski AM, Natesampillai S, Bren GD, Badley AD. Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cells. Molecular and Cellular Therapies. 2: 1. PMID 26057236 DOI: 10.1186/2052-8426-2-1 |
0.402 |
|
| 2014 |
Cummins NW, Badley AD. Making sense of how HIV kills infected CD4 T cells: implications for HIV cure. Molecular and Cellular Therapies. 2: 20. PMID 26056587 DOI: 10.1186/2052-8426-2-20 |
0.46 |
|
| 2014 |
Badley AD. "Much ado to achieve nothing: prospects for curing HIV infection". Molecular and Cellular Therapies. 2: 9. PMID 26056578 DOI: 10.1186/2052-8426-2-9 |
0.433 |
|
| 2014 |
Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation. The Journal of Cell Biology. 206: 867-76. PMID 25246614 DOI: 10.1083/Jcb.201405051 |
0.496 |
|
| 2014 |
Cummins NW, Neuhaus J, Sainski AM, Strausbauch MA, Wettstein PJ, Lewin SR, Plana M, Rizza SA, Temesgen Z, Touloumi G, Freiberg M, Neaton J, Badley AD. Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41. Aids Research and Human Retroviruses. 30: 476-9. PMID 24344953 DOI: 10.1089/Aid.2013.0243 |
0.329 |
|
| 2014 |
Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Wei Meng X, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Correction to Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation [Journal of Cell Biology, 206, 7, (2014), 867-876] Journal of Cell Biology. 207: 159. DOI: 10.1083/Jcb.20140505109252014C |
0.385 |
|
| 2013 |
Badley AD, Sainski A, Wightman F, Lewin SR. Altering cell death pathways as an approach to cure HIV infection. Cell Death & Disease. 4: e718. PMID 23846220 DOI: 10.1038/cddis.2013.248 |
0.483 |
|
| 2013 |
Cummins NW, Badley AD. Anti-apoptotic mechanisms of HIV: lessons and novel approaches to curing HIV. Cellular and Molecular Life Sciences : Cmls. 70: 3355-63. PMID 23275944 DOI: 10.1007/s00018-012-1239-3 |
0.465 |
|
| 2013 |
Rizza S, Cummins N, el Atrouni W, Badley A, Dababneh A, Temesgen Z. Advances in the treatment of HIV and chronic hepatitis C virus infection: A report from the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) Drugs of the Future. 38: 325. DOI: 10.1358/dof.2013.038.05.1968671 |
0.314 |
|
| 2012 |
Baker JV, Neuhaus J, Duprez D, Freiberg M, Bernardino JI, Badley AD, Nixon DE, Lundgren JD, Tracy RP, Neaton JD. HIV replication, inflammation, and the effect of starting antiretroviral therapy on plasma asymmetric dimethylarginine, a novel marker of endothelial dysfunction. Journal of Acquired Immune Deficiency Syndromes (1999). 60: 128-34. PMID 22421746 DOI: 10.1097/Qai.0B013E318252F99F |
0.368 |
|
| 2011 |
Rizza SA, Challagundla KB, Natesampillai S, Bren GD, Sykora J, Walczak H, Badley AD. TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes. Plos One. 6: e27171. PMID 22110611 DOI: 10.1371/journal.pone.0027171 |
0.342 |
|
| 2011 |
Cummins NW, Klicpera A, Sainski AM, Bren GD, Khosla S, Westendorf JJ, Badley AD. Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. Plos One. 6: e24876. PMID 21931863 DOI: 10.1371/journal.pone.0024876 |
0.41 |
|
| 2011 |
Schnepple DJ, Shepard B, Bren GD, Cummins NW, Natesampillai S, Trushin S, Algeciras-Schimnich A, Meng XW, Sainski AM, Rizza SA, Kaufmann SH, Badley AD. Isolation of a TRAIL antagonist from the serum of HIV-infected patients Journal of Biological Chemistry. 286: 35742-35754. PMID 21859711 DOI: 10.1074/Jbc.M111.274639 |
0.516 |
|
| 2011 |
Sainski AM, Natesampillai S, Cummins NW, Bren GD, Taylor J, Saenz DT, Poeschla EM, Badley AD. The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak. Journal of Virology. 85: 7965-75. PMID 21653671 DOI: 10.1128/JVI.02515-10 |
0.479 |
|
| 2010 |
Cummins NW, Badley AD. Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death & Disease. 1: e99. PMID 21368875 DOI: 10.1038/cddis.2010.77 |
0.508 |
|
| 2010 |
Natesampillai S, Nie Z, Cummins NW, Jochmans D, Bren GD, Angel JB, Badley AD. Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells. Plos Pathogens. 6: e1001213. PMID 21124822 DOI: 10.1371/journal.ppat.1001213 |
0.484 |
|
| 2010 |
Trushin SA, Bren GD, Badley AD. CXCR4 Tropic HIV-1 gp120 Inhibition of SDF-1α-Induced Chemotaxis Requires Lck and is Associated with Cofilin Phosphorylation. The Open Virology Journal. 4: 157-62. PMID 20835359 DOI: 10.2174/1874357901004010157 |
0.405 |
|
| 2010 |
Taylor JA, Cummins NW, Bren GD, Rizza SA, Kolbert CP, Behrens MD, Knutson KL, Kahl JC, Asmann YW, Badley AD. Casp8p41 expression in primary T cells induces a proinflammatory response. Aids (London, England). 24: 1251-8. PMID 20299954 DOI: 10.1097/Qad.0B013E3283389E90 |
0.495 |
|
| 2009 |
Shepard BD, Badley AD. The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases. Anti-Infective Agents in Medicinal Chemistry. 8: 87-101. PMID 21857885 DOI: 10.2174/187152109787846060 |
0.335 |
|
| 2009 |
Cummins N, Badley A. The TRAIL to viral pathogenesis: the good, the bad and the ugly. Current Molecular Medicine. 9: 495-505. PMID 19519406 DOI: 10.2174/156652409788167078 |
0.445 |
|
| 2009 |
Bren GD, Trushin SA, Whitman J, Shepard B, Badley AD. HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8. Plos One. 4: e4875. PMID 19287489 DOI: 10.1371/journal.pone.0004875 |
0.425 |
|
| 2009 |
O'Hara SP, Small AJ, Gajdos GB, Badley AD, Chen XM, Larusso NF. HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum. The Journal of Infectious Diseases. 199: 1195-204. PMID 19265483 DOI: 10.1086/597387 |
0.331 |
|
| 2009 |
Babu CK, Suwansrinon K, Bren GD, Badley AD, Rizza SA. HIV induces TRAIL sensitivity in hepatocytes. Plos One. 4: e4623. PMID 19247452 DOI: 10.1371/journal.pone.0004623 |
0.349 |
|
| 2008 |
Nie Z, Bren GD, Rizza SA, Badley AD. HIV Protease Cleavage of Procaspase 8 is Necessary for Death of HIV-Infected Cells. The Open Virology Journal. 2: 1-7. PMID 18818774 DOI: 10.2174/1874357900802010001 |
0.479 |
|
| 2008 |
Shepard BD, De Forni D, McNamara DR, Foli A, Rizza SA, Abraham RS, Knutson K, Wettstein PJ, Lori F, Badley AD. Beneficial effect of TRAIL on HIV burden, without detectable immune consequences. Plos One. 3: e3096. PMID 18769477 DOI: 10.1371/Journal.Pone.0003096 |
0.481 |
|
| 2008 |
Hisatomi T, Nakazawa T, Noda K, Almulki L, Miyahara S, Nakao S, Ito Y, She H, Kohno R, Michaud N, Ishibashi T, Hafezi-Moghadam A, Badley AD, Kroemer G, Miller JW. HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. The Journal of Clinical Investigation. 118: 2025-38. PMID 18497877 DOI: 10.1172/Jci34267 |
0.39 |
|
| 2008 |
Bren GD, Whitman J, Cummins N, Shepard B, Rizza SA, Trushin SA, Badley AD. Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication. Plos One. 3: e2112. PMID 18461165 DOI: 10.1371/journal.pone.0002112 |
0.481 |
|
| 2008 |
Rizza SA, Badley AD. HIV protease inhibitors impact on apoptosis. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 4: 75-9. PMID 18220972 |
0.49 |
|
| 2008 |
Rizza SR, Tangalos EG, McClees MD, Strausbauch MA, Targonski PV, McKean DJ, Wettstein PJ, Badley AD. Nelfinavir monotherapy increases naïve T-cell numbers in HIV-negative healthy young adults. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1605-9. PMID 17981652 |
0.39 |
|
| 2007 |
Algeciras-Schimnich A, Belzacq-Casagrande AS, Bren GD, Nie Z, Taylor JA, Rizza SA, Brenner C, Badley AD. Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria. The Open Virology Journal. 1: 39-46. PMID 18818773 DOI: 10.2174/1874357900701010039 |
0.45 |
|
| 2007 |
Vlahakis SR, Bennett SA, Whitehead SN, Badley AD. HIV protease inhibitors modulate apoptosis signaling in vitro and in vivo. Apoptosis : An International Journal On Programmed Cell Death. 12: 969-77. PMID 17453162 DOI: 10.1007/s10495-007-0755-3 |
0.489 |
|
| 2007 |
Nie Z, Bren GD, Vlahakis SR, Schimnich AA, Brenchley JM, Trushin SA, Warren S, Schnepple DJ, Kovacs CM, Loutfy MR, Douek DC, Badley AD. Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo. Journal of Virology. 81: 6947-56. PMID 17442709 DOI: 10.1128/JVI.02798-06 |
0.514 |
|
| 2007 |
Trushin SA, Algeciras-Schimnich A, Vlahakis SR, Bren GD, Warren S, Schnepple DJ, Badley AD. Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4. Journal of Immunology (Baltimore, Md. : 1950). 178: 4846-53. PMID 17404265 |
0.319 |
|
| 2007 |
Vlahakis SR, Bren GD, Algeciras-Schimnich A, Trushin SA, Schnepple DJ, Badley AD. Flying in the face of resistance: antiviral-independent benefit of HIV protease inhibitors on T-cell survival. Clinical Pharmacology and Therapeutics. 82: 294-9. PMID 17361127 DOI: 10.1038/sj.clpt.6100140 |
0.514 |
|
| 2007 |
O'Hara SP, Small AJ, Nelson JB, Badley AD, Chen XM, Gores GJ, Larusso NF. The human immunodeficiency virus type 1 tat protein enhances Cryptosporidium parvum-induced apoptosis in cholangiocytes via a Fas ligand-dependent mechanism. Infection and Immunity. 75: 684-96. PMID 17118988 DOI: 10.1128/IAI.01348-06 |
0.49 |
|
| 2006 |
Badley AD. In vitro and in vivo effects of HIV protease inhibitors on apoptosis. Cell Death and Differentiation. 924-31. PMID 15761470 DOI: 10.1038/sj.cdd.4401580 |
0.451 |
|
| 2006 |
Kravcik S, Gallicano K, Roth V, Cassol S, Hawley-Foss N, Badley A, Cameron DW. Cerebrospinal Fluid HIV RNA and Drug Levels With Combination Ritonavir and Saquinavir Journal of Acquired Immune Deficiency Syndromes. 21: 371. DOI: 10.1097/00042560-199908150-00003 |
0.423 |
|
| 2005 |
Graham DB, Bell MP, Huntoon CJ, Weaver JG, Hawley N, Badley AD, McKean DJ. Increased thymic output in HIV-negative patients after antiretroviral therapy. Aids (London, England). 19: 1467-72. PMID 16135899 |
0.382 |
|
| 2005 |
Trushin SA, Bren GD, Asin S, Pennington KN, Paya CV, Badley AD. Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCalpha and PKCtheta. Journal of Virology. 79: 9821-30. PMID 16014943 DOI: 10.1128/JVI.79.15.9821-9830.2005 |
0.477 |
|
| 2005 |
Lum JJ, Bren G, McClure R, Badley AD. Elimination of senescent neutrophils by TNF-related apoptosis-inducing [corrected] ligand. Journal of Immunology (Baltimore, Md. : 1950). 175: 1232-8. PMID 16002727 DOI: 10.4049/Jimmunol.175.2.1232 |
0.58 |
|
| 2005 |
Lum JJ, Schnepple DJ, Badley AD. Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions. Aids (London, England). 19: 1125-33. PMID 15990565 DOI: 10.1097/01.Aids.0000176212.16205.23 |
0.663 |
|
| 2005 |
Weaver JG, Tarze A, Moffat TC, Lebras M, Deniaud A, Brenner C, Bren GD, Morin MY, Phenix BN, Dong L, Jiang SX, Sim VL, Zurakowski B, Lallier J, Hardin H, ... ... Badley AD, et al. Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. The Journal of Clinical Investigation. 115: 1828-38. PMID 15937550 DOI: 10.1172/JCI22954 |
0.412 |
|
| 2005 |
Cuerrier D, Nie Z, Badley AD, Davies PL. Ritonavir does not inhibit calpain in vitro. Biochemical and Biophysical Research Communications. 327: 208-11. PMID 15629450 DOI: 10.1016/J.Bbrc.2004.11.161 |
0.367 |
|
| 2005 |
Lum JJ, Bren G, McClure R, Badley AD. Elimination of senescent neutrophils by TNF-related apopotosis-inducing ligand The Journal of Immunology. 175: 3446.1-3446. DOI: 10.4049/jimmunol.175.5.3446 |
0.545 |
|
| 2004 |
Buenz EJ, Badley AD. Impact of mitochondrial regulation of apoptosis on the pathogenesis and treatment of HIV-1-induced immunodeficiency. Mitochondrion. 4: 235-54. PMID 16120389 DOI: 10.1016/j.mito.2004.05.017 |
0.52 |
|
| 2004 |
Zhang X, Lalezari JP, Badley AD, Dorr A, Kolis SJ, Kinchelow T, Patel IH. Assessment of drug-drug interaction potential of enfuvirtide in human immunodeficiency virus type 1-infected patients. Clinical Pharmacology and Therapeutics. 75: 558-68. PMID 15179410 DOI: 10.1016/j.clpt.2004.02.003 |
0.367 |
|
| 2004 |
Lum JJ, Schnepple DJ, Nie Z, Sanchez-Dardon J, Mbisa GL, Mihowich J, Hawley N, Narayan S, Kim JE, Lynch DH, Badley AD. Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity. Journal of Virology. 78: 6033-42. PMID 15141001 DOI: 10.1128/Jvi.78.11.6033-6042.2004 |
0.61 |
|
| 2004 |
Owen C, Kazim F, Badley AD. Effect on CD4 T-cell count of replacing protease inhibitors in patients with successful HIV suppression: a meta-analysis. Aids (London, England). 18: 693-5. PMID 15090777 |
0.391 |
|
| 2004 |
Cohen I, Boya P, Zhao L, Métivier D, Andreau K, Perfettini JL, Weaver JG, Badley A, Taylor EW, Kroemer G. Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1. Apoptosis : An International Journal On Programmed Cell Death. 9: 181-92. PMID 15004515 DOI: 10.1023/B:Appt.0000018800.87358.Ba |
0.486 |
|
| 2004 |
Cooper CL, Phenix B, Mbisa G, Lum JJ, Parato K, Hawley N, Angel JB, Badley AD. Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo. Frontiers in Bioscience : a Journal and Virtual Library. 9: 338-41. PMID 14766370 DOI: 10.2741/1230 |
0.689 |
|
| 2003 |
Lum JJ, Badley AD. Resistance to apoptosis: mechanism for the development of HIV reservoirs. Current Hiv Research. 1: 261-74. PMID 15046251 DOI: 10.2174/1570162033485203 |
0.699 |
|
| 2003 |
Badley AD, Roumier T, Lum JJ, Kroemer G. Mitochondrion-mediated apoptosis in HIV-1 infection. Trends in Pharmacological Sciences. 24: 298-305. PMID 12823956 DOI: 10.1016/S0165-6147(03)00125-1 |
0.682 |
|
| 2003 |
Lum JJ, Cohen OJ, Nie Z, Weaver JG, Gomez TS, Yao XJ, Lynch D, Pilon AA, Hawley N, Kim JE, Chen Z, Montpetit M, Sanchez-Dardon J, Cohen EA, Badley AD. Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. The Journal of Clinical Investigation. 111: 1547-54. PMID 12750404 DOI: 10.1172/Jci16233 |
0.688 |
|
| 2003 |
Phenix BN, Cooper C, Owen C, Badley AD. Modulation of apoptosis by HIV protease inhibitors. Apoptosis : An International Journal On Programmed Cell Death. 7: 295-312. PMID 12101389 DOI: 10.1023/A:1016168411221 |
0.466 |
|
| 2003 |
Zhang X, Patel IH, Lalezari J, Badley A, Hawker N, Dorr A, Kolis SJ, Kinchelow T. Assessment of Metabolic Inhibition Potential of Enfuvirtide Using a 5-Drug Cocktail in HIV-1 Infected Patients Clinical Pharmacology & Therapeutics. 73: P81-P81. DOI: 10.1016/S0009-9236(03)90658-8 |
0.453 |
|
| 2002 |
Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation Cell Death and Differentiation. 9: 1172-1184. PMID 12404116 DOI: 10.1038/Sj.Cdd.4401094 |
0.697 |
|
| 2002 |
Pilon AA, Lum JJ, Sanchez-Dardon J, Phenix BN, Douglas R, Badley AD. Induction of apoptosis by a nonnucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitor. Antimicrobial Agents and Chemotherapy. 46: 2687-91. PMID 12121958 DOI: 10.1128/Aac.46.8.2687-2691.2002 |
0.601 |
|
| 2002 |
Parato KG, Kumar A, Badley AD, Sanchez-Dardon JL, Chambers KA, Young CD, Lim WT, Kravcik S, Cameron DW, Angel JB. Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10. Aids (London, England). 16: 1251-6. PMID 12045490 DOI: 10.1097/00002030-200206140-00007 |
0.411 |
|
| 2002 |
Phenix BN, Badley AD. Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection. Biochimie. 84: 251-64. PMID 12022956 |
0.506 |
|
| 2002 |
Kravcik S, Magill A, Sanghvi B, Ogden R, Cameron WD, Lewis R, Yu G, Badley AD. Comparative CD4 T-cell responses of reverse transcriptase inhibitor therapy with or without nelfinavir matched for viral exposure. Hiv Clinical Trials. 2: 160-70. PMID 11590524 DOI: 10.1310/F45L-FDKK-Y48N-N2BT |
0.349 |
|
| 2001 |
Cooper CL, Badley AD, Angel JB. Characteristics of hepatitis C virus infection in HIV-infected people. The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses. 12: 157-63. PMID 18159334 DOI: 10.1155/2001/542056 |
0.315 |
|
| 2001 |
Lum JJ, Pilon AA, Sanchez-Dardon J, Phenix BN, Kim JE, Mihowich J, Jamison K, Hawley-Foss N, Lynch DH, Badley AD. Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. Journal of Virology. 75: 11128-36. PMID 11602752 DOI: 10.1128/Jvi.75.22.11128-11136.2001 |
0.699 |
|
| 2001 |
Teixeira L, Valdez H, McCune JM, Koup RA, Badley AD, Hellerstein MK, Napolitano LA, Douek DC, Mbisa G, Deeks S, Harris JM, Barbour JD, Gross BH, Francis IR, Halvorsen R, et al. Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function. Aids (London, England). 15: 1749-56. PMID 11579235 DOI: 10.1097/00002030-200109280-00002 |
0.414 |
|
| 2001 |
Phenix BN, Lum JJ, Nie Z, Sanchez-Dardon J, Badley AD. Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss. Blood. 98: 1078-85. PMID 11493454 DOI: 10.1182/Blood.V98.4.1078 |
0.655 |
|
| 2001 |
Maslove DM, Ni LW, Hawley-Foss NC, Badley AD, Copeland KF. Modulation of HIV transcription by CD8(+) cells is mediated via multiple elements of the long terminal repeat. Clinical and Experimental Immunology. 125: 102-9. PMID 11472432 DOI: 10.1046/j.1365-2249.2001.01576.x |
0.331 |
|
| 2001 |
Hawley-Foss N, Mbisa G, Lum JJ, Pilon AA, Angel JB, Garber G, Badley AD. Effect of cessation of highly active antiretroviral therapy during a discordant response: implications for scheduled therapeutic interruptions. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 33: 344-8. PMID 11438900 DOI: 10.1086/321902 |
0.567 |
|
| 2001 |
Angel JB, Parato KG, Kumar A, Kravcik S, Badley AD, Fex C, Ashby D, Sun E, Cameron DW. Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression. The Journal of Infectious Diseases. 183: 546-54. PMID 11170979 DOI: 10.1086/318547 |
0.378 |
|
| 2000 |
Phenix BN, Angel JB, Mandy F, Kravcik S, Parato K, Chambers KA, Gallicano K, Hawley-Foss N, Cassol S, Cameron DW, Badley AD. Decreased HIV-associated T cell apoptosis by HIV protease inhibitors. Aids Research and Human Retroviruses. 16: 559-67. PMID 10777146 DOI: 10.1089/088922200308972 |
0.494 |
|
| 2000 |
Badley AD, Pilon AA, Landay A, Lynch DH. Mechanisms of HIV-associated lymphocyte apoptosis Blood. 96: 2951-2964. DOI: 10.1182/BLOOD.V96.9.2951.H8002951_2951_2964 |
0.527 |
|
| 1999 |
Dockrell DH, Badley AD, Algeciras-Schimnich A, Simpson M, Schut R, Lynch DH, Paya CV. Activation-induced CD4+ T cell death in HIV-positive individuals correlates with Fas susceptibility, CD4+ T cell count, and HIV plasma viral copy number. Aids Research and Human Retroviruses. 15: 1509-18. PMID 10580401 DOI: 10.1089/088922299309793 |
0.42 |
|
| 1999 |
Badley AD, Parato K, Cameron DW, Kravcik S, Phenix BN, Ashby D, Kumar A, Lynch DH, Tschopp J, Angel JB. Dynamic correlation of apoptosis and immune activation during treatment of HIV infection. Cell Death and Differentiation. 6: 420-32. PMID 10381636 DOI: 10.1038/Sj.Cdd.4400509 |
0.528 |
|
| 1998 |
Badley AD, Dockrell DH, Algeciras A, Ziesmer S, Landay A, Lederman MM, Connick E, Kessler H, Kuritzkes D, Lynch DH, Roche P, Yagita H, Paya CV. In vivo analysis of Fas/FasL interactions in HIV-infected patients. The Journal of Clinical Investigation. 102: 79-87. PMID 9649560 DOI: 10.1172/Jci2691 |
0.46 |
|
| 1998 |
Dockrell DH, Badley AD, Villacian JS, Heppelmann CJ, Algeciras A, Ziesmer S, Yagita H, Lynch DH, Roche PC, Leibson PJ, Paya CV. The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection. The Journal of Clinical Investigation. 101: 2394-405. PMID 9616211 DOI: 10.1172/JCI1171 |
0.402 |
|
| 1997 |
Badley AD, Dockrell D, Paya CV. Apoptosis in AIDS. Advances in Pharmacology (San Diego, Calif.). 41: 271-94. PMID 9204149 DOI: 10.1016/S1054-3589(08)61062-5 |
0.341 |
|
| 1997 |
Badley AD, Dockrell D, Simpson M, Schut R, Lynch DH, Leibson P, Paya CV. Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor. The Journal of Experimental Medicine. 185: 55-64. PMID 8996241 DOI: 10.1084/jem.185.1.55 |
0.478 |
|
| 1996 |
Badley AD, McElhinny JA, Leibson PJ, Lynch DH, Alderson MR, Paya CV. Upregulation of fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes Journal of Virology. 70: 199-206. PMID 8523526 DOI: 10.1128/jvi.70.1.199-206.1996 |
0.527 |
|
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