Owen McGuinness - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Endocrinology Biology, Cell Biology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Smith EC, Patel JN, Wahba A, Cluckey A, Celedonio J, Park J, Hannah L, Lonce S, Shibao CA, Paranjape SY, Diedrich A, McGuinness O, Wasserman DH, Biaggioni I, Gamboa A. Acute Sympathetic Blockade Improves Insulin-Mediated Microvascular Blood Flow in the Forearm of Adult Human Subjects With Obesity. Journal of the American Heart Association. e030775. PMID 39119951 DOI: 10.1161/JAHA.123.030775  0.455
2024 Winn NC, Schleh MW, Garcia JN, Lantier L, McGuinness OP, Blair JA, Hasty AH, Wasserman DH. Insulin at the intersection of thermoregulation and glucose homeostasis. Molecular Metabolism. 81: 101901. PMID 38354854 DOI: 10.1016/j.molmet.2024.101901  0.525
2023 Winn NC, Schleh MW, Garcia JN, Lantier L, McGuinness OP, Blair JA, Hasty AH, Wasserman DH. Insulin at the Intersection of Thermoregulation and Glucose Homeostasis. Biorxiv : the Preprint Server For Biology. PMID 38014310 DOI: 10.1101/2023.11.17.566254  0.524
2023 Ceddia RP, Zurawski Z, Thompson Gray A, Adegboye F, McDonald-Boyer A, Shi F, Liu D, Maldonado J, Feng J, Li Y, Alford S, Ayala JE, McGuinness OP, Collins S, Hamm HE. Gβγ-SNAP25 exocytotic brake removal enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity. The Journal of Clinical Investigation. PMID 37561580 DOI: 10.1172/JCI160617  0.402
2023 Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis. Metabolism: Clinical and Experimental. 144: 155589. PMID 37182789 DOI: 10.1016/j.metabol.2023.155589  0.318
2022 Ayala JE, Lantier L, McGuinness OP, Wasserman DH. Peeling back the layers of the glucose clamp. Nature Metabolism. PMID 35477775 DOI: 10.1038/s42255-022-00573-1  0.36
2021 van der Zande HJP, Lambooij JM, Chavanelle V, Zawistowska-Deniziak A, Otero Y, Otto F, Lantier L, McGuinness OP, Le Joubioux F, Giera M, Maugard T, Peltier SL, Sirvent P, Guigas B. Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice. International Journal of Obesity (2005). PMID 34079069 DOI: 10.1038/s41366-021-00870-x  0.342
2020 Bosma KJ, Rahim M, Oeser JK, McGuinness OP, Young JD, O'Brien RM. G6PC2 Confers Protection Against Hypoglycemia Upon Ketogenic Diet Feeding and Prolonged Fasting. Molecular Metabolism. 101043. PMID 32569842 DOI: 10.1016/J.Molmet.2020.101043  0.517
2020 Syring KE, Bosma KJ, Goleva SB, Singh K, Oeser JK, Lopez CA, Skaar EP, McGuinness OP, Davis LK, Powell DR, O'Brien RM. Potential positive and negative consequences of ZnT8 inhibition. The Journal of Endocrinology. PMID 32485672 DOI: 10.1530/Joe-20-0138  0.432
2020 Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Feigh M, Veidal SS, Lantier L, McGuinness OP, Grimsby J, et al. Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. Nature Metabolism. 2: 413-431. PMID 32478287 DOI: 10.1038/s42255-020-0209-6  0.358
2020 Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC. Dapagliflozin does not directly affect human α or β cells. Endocrinology. PMID 32428240 DOI: 10.1210/endocr/bqaa080  0.457
2020 Bosma KJ, Rahim M, Singh K, Goleva SB, Wall ML, Xia J, Syring KE, Oeser JK, Poffenberger G, McGuinness OP, Means AL, Powers AC, Lee WH, Davis LK, Young JD, et al. Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose. Journal of Molecular Endocrinology. PMID 32213654 DOI: 10.1530/Jme-20-0031  0.479
2020 McClatchey PM, Williams IM, Xu Z, Mignemi NA, Hughey CC, McGuinness OP, Beckman JA, Wasserman DH, Poole DC, Akerstrom T, Goldman D, Fraser GM, Ellis CG. Reply to Letter to the Editor: Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo. American Journal of Physiology. Endocrinology and Metabolism. 318: E313-E317. PMID 32068464 DOI: 10.1152/Ajpendo.00508.2019  0.46
2020 Laker RC, Lantier L, Mcguinness O, Will S, Kuszpit K, Alfaro AR, Jermutus L, Rhodes CJ. 1800-P: Cotadutide, a GLP-1/GCG Receptor Co-Agonist, Improves Insulin Sensitivity and Restores Normal Insulin Secretory Capacity in DIO Mice Diabetes. 69. DOI: 10.2337/Db20-1800-P  0.576
2019 Watanabe M, Singhal G, Fisher FM, Beck TC, Morgan DA, Socciarelli F, Mather ML, Risi R, Bourke J, Rahmouni K, McGuinness OP, Flier JS, Maratos-Flier E. Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis. Endocrine. PMID 31728756 DOI: 10.1007/S12020-019-02124-3  0.332
2019 McClatchey PM, Williams IM, Xu Z, Mignemi NA, Hughey CC, McGuinness OP, Beckman JA, Wasserman DH. Perfusion Controls Muscle Glucose Uptake by Altering the Rate of Glucose Dispersion In Vivo. American Journal of Physiology. Endocrinology and Metabolism. PMID 31526289 DOI: 10.1152/ajpendo.00260.2019  0.479
2019 Peterson KR, Gutierrez DA, Kikuchi T, Anderson-Baucum EK, Winn NC, Shuey MM, Bolus WR, McGuinness OP, Hasty AH. Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency. American Journal of Physiology. Endocrinology and Metabolism. PMID 31084499 DOI: 10.1152/Ajpendo.00042.2019  0.353
2019 Mignemi NA, McClatchey PM, Kilchrist KV, Williams IM, Millis BA, Syring KE, Duvall CL, Wasserman DH, McGuinness OP. Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis. American Journal of Physiology. Endocrinology and Metabolism. PMID 30860883 DOI: 10.1152/Ajpendo.00501.2018  0.415
2019 Syring KE, Cyphert TJ, Beck TC, Flynn CR, Mignemi NA, McGuinness OP. Systemic bile acids induce insulin resistance in a TGR5-independent manner. American Journal of Physiology. Endocrinology and Metabolism. PMID 30779633 DOI: 10.1152/Ajpendo.00362.2018  0.49
2019 SYRING K, MIGNEMI NA, MCGUINNESS OP. 1820-P: Autonomic Tone Is Necessary for Bile Acid-Induced Hepatic Insulin Resistance Diabetes. 68: 1820-P. DOI: 10.2337/DB19-1820-P  0.362
2019 MCCLATCHEY PM, WILLIAMS IM, MIGNEMI NA, HUGHEY CC, MCGUINNESS OP, BECKMAN JA, WASSERMAN D. 172-OR: Perfusion Controls Insulin-Stimulated Glucose Uptake in Skeletal Muscle by Altering the Rate of Glucose Dispersion In Vivo Diabetes. 68: 172-OR. DOI: 10.2337/DB19-172-OR  0.51
2018 Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, ... ... McGuinness OP, et al. Hepatic Gi signaling regulates whole-body glucose homeostasis. The Journal of Clinical Investigation. PMID 29337301 DOI: 10.1172/Jci94505  0.457
2016 Syring KE, Boortz KA, Oeser JK, Ustione A, Platt KA, Shadoan MK, McGuinness OP, Piston DW, Powell DR, O'Brien RM. Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion. Endocrinology. en20161573. PMID 27754787 DOI: 10.1210/en.2016-1573  0.487
2016 Boortz KA, Syring KE, Lee RA, Dai C, Oeser JK, McGuinness OP, Wang JC, O'Brien RM. G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance. Endocrinology. en20161678. PMID 27653037 DOI: 10.1210/En.2016-1678  0.527
2016 Boortz KA, Syring KE, Dai C, Pound LD, Oeser JK, Jacobson DA, Wang JC, McGuinness OP, Powers AC, O'Brien RM. G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress. Endocrinology. en20161245. PMID 27300767 DOI: 10.1210/En.2016-1245  0.387
2015 Otero YF, Mulligan KX, Barnes TM, Ford EA, Malabanan CM, Zong H, Pessin JE, Wasserman DH, McGuinness OP. Enhanced Glucose Transport, but not Phosphorylation Capacity, Ameliorates Lipopolysaccharide-Induced Impairments in Insulin Stimulated-Muscle Glucose Uptake. Shock (Augusta, Ga.). PMID 26682946 DOI: 10.1097/Shk.0000000000000550  0.783
2015 Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP. NF-κB-dependent airway inflammation triggers systemic insulin resistance. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R1144-52. PMID 26377563 DOI: 10.1152/Ajpregu.00442.2014  0.444
2015 House LM, Morris RT, Barnes TM, Lantier L, Cyphert TJ, McGuinness OP, Otero YF. Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance. Cardiovascular Diabetology. 14: 56. PMID 25986700 DOI: 10.1186/s12933-015-0223-2  0.39
2014 Cordoba-Chacon J, Gahete MD, McGuinness OP, Kineman RD. Differential impact of selective GH deficiency and endogenous GH excess on insulin-mediated actions in muscle and liver of male mice. American Journal of Physiology. Endocrinology and Metabolism. 307: E928-34. PMID 25269484 DOI: 10.1152/ajpendo.00420.2014  0.507
2014 Otero YF, Stafford JM, McGuinness OP. Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux. The Journal of Biological Chemistry. 289: 20462-9. PMID 24907277 DOI: 10.1074/Jbc.R114.576355  0.501
2014 Chen SS, Otero YF, Mulligan KX, Lundblad TM, Williams PE, McGuinness OP. Liver, but not muscle, has an entrainable metabolic memory. Plos One. 9: e86164. PMID 24465939 DOI: 10.1371/Journal.Pone.0086164  0.816
2013 Cappel DA, Palmisano BT, Emfinger CH, Martinez MN, McGuinness OP, Stafford JM. Cholesteryl ester transfer protein protects against insulin resistance in obese female mice. Molecular Metabolism. 2: 457-67. PMID 24327961 DOI: 10.1016/J.Molmet.2013.08.007  0.315
2013 Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton LC, Lefai E, Simon MC, Maher JJ, ... ... McGuinness OP, et al. A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nature Medicine. 19: 1331-7. PMID 24037094 DOI: 10.1038/Nm.3295  0.805
2013 Shi SQ, Ansari TS, McGuinness OP, Wasserman DH, Johnson CH. Circadian disruption leads to insulin resistance and obesity. Current Biology : Cb. 23: 372-81. PMID 23434278 DOI: 10.1016/J.Cub.2013.01.048  0.372
2013 Pound LD, Oeser JK, O'Brien TP, Wang Y, Faulman CJ, Dadi PK, Jacobson DA, Hutton JC, McGuinness OP, Shiota M, O'Brien RM. G6PC2: a negative regulator of basal glucose-stimulated insulin secretion. Diabetes. 62: 1547-56. PMID 23274894 DOI: 10.2337/Db12-1067  0.534
2013 Zhu L, Brown WC, Cai Q, Krust A, Chambon P, McGuinness OP, Stafford JM. Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance. Diabetes. 62: 424-34. PMID 22966069 DOI: 10.2337/Db11-1718  0.473
2012 Berglund ED, Li CY, Ayala JE, McGuinness OP, Wasserman DH. Regulation of Endogenous Glucose Production in Glucose Transporter 4 Over-Expressing Mice Plos One. 7. PMID 23285006 DOI: 10.1371/journal.pone.0052355  0.798
2012 Kocalis HE, Turney MK, Printz RL, Laryea GN, Muglia LJ, Davies SS, Stanwood GD, McGuinness OP, Niswender KD. Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity. Plos One. 7: e42981. PMID 22916190 DOI: 10.1371/Journal.Pone.0042981  0.724
2012 Ganesh Kumar K, Zhang J, Gao S, Rossi J, McGuinness OP, Halem HH, Culler MD, Mynatt RL, Butler AA. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity (Silver Spring, Md.). 20: 1394-402. PMID 22318315 DOI: 10.1038/Oby.2012.31  0.397
2012 Mulligan KX, Morris RT, Otero YF, Wasserman DH, McGuinness OP. Disassociation of muscle insulin signaling and insulin-stimulated glucose uptake during endotoxemia. Plos One. 7: e30160. PMID 22276152 DOI: 10.1371/Journal.Pone.0030160  0.798
2011 Ayala JE, Bracy DP, Malabanan C, James FD, Ansari T, Fueger PT, McGuinness OP, Wasserman DH. Hyperinsulinemic-euglycemic clamps in conscious, unrestrained mice. Journal of Visualized Experiments : Jove. PMID 22126863 DOI: 10.3791/3188  0.516
2011 Johnson PM, Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Continuous low-dose fructose infusion does not reverse glucagon-mediated decrease in hepatic glucose utilization. Metabolism: Clinical and Experimental. 60: 867-73. PMID 20940071 DOI: 10.1016/j.metabol.2010.08.006  0.587
2011 Tweedell A, Mulligan KX, Martel JE, Chueh FY, Santomango T, McGuinness OP. Metabolic response to endotoxin in vivo in the conscious mouse: role of interleukin-6. Metabolism: Clinical and Experimental. 60: 92-8. PMID 20102773 DOI: 10.1016/J.Metabol.2009.12.022  0.753
2010 Vaitheesvaran B, Chueh FY, Xu J, Trujillo C, Saad MF, Lee WN, McGuinness OP, Kurland IJ. Advantages of dynamic "closed loop" stable isotope flux phenotyping over static "open loop" clamps in detecting silent genetic and dietary phenotypes. Metabolomics : Official Journal of the Metabolomic Society. 6: 180-190. PMID 20445758 DOI: 10.1007/s11306-009-0190-2  0.502
2010 Irimia JM, Meyer CM, Peper CL, Zhai L, Bock CB, Previs SF, McGuinness OP, DePaoli-Roach A, Roach PJ. Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice. The Journal of Biological Chemistry. 285: 12851-61. PMID 20178984 DOI: 10.1074/Jbc.M110.106534  0.459
2009 McGuinness OP, Ayala JE, Laughlin MR, Wasserman DH. NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse. American Journal of Physiology. Endocrinology and Metabolism. 297: E849-55. PMID 19638507 DOI: 10.1152/Ajpendo.90996.2008  0.413
2009 Pound LD, Sarkar SA, Benninger RK, Wang Y, Suwanichkul A, Shadoan MK, Printz RL, Oeser JK, Lee CE, Piston DW, McGuinness OP, Hutton JC, Powell DR, O'Brien RM. Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. The Biochemical Journal. 421: 371-6. PMID 19450229 DOI: 10.1042/Bj20090530  0.478
2009 Gao Z, Yin J, Zhang J, He Q, McGuinness OP, Ye J. Inactivation of NF-ΚB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K Journal of Biological Chemistry. 284: 18368-18376. PMID 19433583 DOI: 10.1074/jbc.M109.007260  0.493
2009 Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN. Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metabolism. 9: 350-61. PMID 19356716 DOI: 10.1016/J.Cmet.2009.02.007  0.46
2009 Chen SS, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Glucagon-mediated impairments in hepatic and peripheral tissue nutrient disposal are not aggravated by increased lipid availability. American Journal of Physiology. Endocrinology and Metabolism. 296: E1172-8. PMID 19208853 DOI: 10.1152/ajpendo.90821.2008  0.591
2007 McGuinness OP. Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 823; author reply 82. PMID 17323468 DOI: 10.1152/Japplphysiol.01353.2006  0.489
2007 Wang Y, Martin CC, Oeser JK, Sarkar S, McGuinness OP, Hutton JC, O'Brien RM. Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype. Diabetologia. 50: 774-8. PMID 17265032 DOI: 10.1007/S00125-006-0564-1  0.348
2007 Chen SS, Zhang Y, Santomango TS, Williams PE, Lacy DB, McGuinness OP. Glucagon chronically impairs hepatic and muscle glucose disposal. American Journal of Physiology. Endocrinology and Metabolism. 292: E928-35. PMID 17132827 DOI: 10.1152/ajpendo.00063.2006  0.616
2006 Rao R, Hao CM, Redha R, Wasserman DH, McGuinness OP, Breyer MD. Glycogen synthase kinase 3 inhibition improves insulin-stimulated glucose metabolism but not hypertension in high-fat-fed C57BL/6J mice. Diabetologia. 50: 452-60. PMID 17151860 DOI: 10.1007/S00125-006-0552-5  0.4
2006 Wang Y, Oeser JK, Yang C, Sarkar S, Hackl SI, Hasty AH, McGuinness OP, Paradee W, Hutton JC, Powell DR, O'Brien RM. Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon. The Journal of Biological Chemistry. 281: 39982-9. PMID 17023421 DOI: 10.1074/Jbc.M605858200  0.429
2006 Chueh FY, Malabanan C, McGuinness OP. Impact of portal glucose delivery on glucose metabolism in conscious, unrestrained mice. American Journal of Physiology. Endocrinology and Metabolism. 291: E1206-11. PMID 16822956 DOI: 10.1152/ajpendo.00608.2005  0.547
2006 Jacobson L, Ansari T, McGuinness OP. Counterregulatory deficits occur within 24 h of a single hypoglycemic episode in conscious, unrestrained, chronically cannulated mice. American Journal of Physiology. Endocrinology and Metabolism. 290: E678-84. PMID 16533951 DOI: 10.1152/ajpendo.00383.2005  0.503
2006 Jacobson L, Ansari T, Potts J, McGuinness OP. Glucocorticoid-deficient corticotropin-releasing hormone knockout mice maintain glucose requirements but not autonomic responses during repeated hypoglycemia. American Journal of Physiology. Endocrinology and Metabolism. 291: E15-22. PMID 16449297 DOI: 10.1152/ajpendo.00526.2005  0.449
2006 Ayala JE, Bracy DP, McGuinness OP, Wasserman DH. Considerations in the design of hyperinsulinemic-euglycemic clamps in the conscious mouse. Diabetes. 55: 390-7. PMID 16443772  0.526
2006 Maddux BA, Chang YN, Accili D, McGuinness OP, Youngren JF, Goldfine ID. Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia. American Journal of Physiology. Endocrinology and Metabolism. 290: E746-9. PMID 16278247 DOI: 10.1152/Ajpendo.00298.2005  0.51
2006 Nunemaker CS, Wasserman DH, McGuinness OP, Sweet IR, Teague JC, Satin LS. Insulin secretion in the conscious mouse is biphasic and pulsatile. American Journal of Physiology. Endocrinology and Metabolism. 290: E523-9. PMID 16249252 DOI: 10.1152/Ajpendo.00392.2005  0.439
2005 Nunemaker CS, Zhang M, Wasserman DH, McGuinness OP, Powers AC, Bertram R, Sherman A, Satin LS. Individual mice can be distinguished by the period of their islet calcium oscillations: is there an intrinsic islet period that is imprinted in vivo? Diabetes. 54: 3517-22. PMID 16306370 DOI: 10.2337/Diabetes.54.12.3517  0.302
2005 McGuinness OP. Defective glucose homeostasis during infection. Annual Review of Nutrition. 25: 9-35. PMID 16011457 DOI: 10.1146/annurev.nutr.24.012003.132159  0.499
2005 Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, Chang C, McGuinness OP. Route-dependent effect of nutritional support on liver glucose uptake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R1319-27. PMID 15994371 DOI: 10.1152/ajpregu.00175.2005  0.586
2005 Grubert JM, Lautz M, Lacy DB, Moore MC, Farmer B, Penaloza A, Cherrington AD, McGuinness OP. Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake. American Journal of Physiology. Endocrinology and Metabolism. 289: E232-40. PMID 15755768 DOI: 10.1152/ajpendo.00567.2004  0.588
2005 Fueger PT, Shearer J, Bracy DP, Posey KA, Pencek RR, McGuinness OP, Wasserman DH. Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice. The Journal of Physiology. 562: 925-35. PMID 15576451 DOI: 10.1113/Jphysiol.2004.076158  0.554
2005 Chen SS, Torres-Sanchez CJ, Hosein N, Zhang Y, Lacy DB, McGuinness OP. Time course of the hepatic adaptation to TPN: interaction with glycogen depletion. American Journal of Physiology. Endocrinology and Metabolism. 288: E163-70. PMID 15339746 DOI: 10.1152/ajpendo.00192.2004  0.41
2004 Rocheleau JV, Walker GM, Head WS, McGuinness OP, Piston DW. Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. 101: 12899-903. PMID 15317941 DOI: 10.1073/Pnas.0405149101  0.318
2004 Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB. Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Diabetes. 53: 336-46. PMID 14747283 DOI: 10.2337/Diabetes.53.2.336  0.316
2004 Chen SS, Donmoyer CM, Pearson DA, Poole A, Zhang Y, Lacy DB, McGuinness OP. Impact of infection on glucose-dependent liver glucose uptake during TPN: interaction with insulin. American Journal of Physiology. Endocrinology and Metabolism. 286: E286-95. PMID 14532169 DOI: 10.1152/Ajpendo.00286.2003  0.834
2003 McGuinness OP, Cherrington AD. Effects of fructose on hepatic glucose metabolism. Current Opinion in Clinical Nutrition and Metabolic Care. 6: 441-8. PMID 12806219 DOI: 10.1097/01.mco.0000078990.96795.cd  0.565
2003 Donmoyer CM, Chen SS, Lacy DB, Pearson DA, Poole A, Zhang Y, McGuinness OP. Infection impairs insulin-dependent hepatic glucose uptake during total parenteral nutrition. American Journal of Physiology. Endocrinology and Metabolism. 284: E574-82. PMID 12441309 DOI: 10.1152/Ajpendo.00035.2002  0.837
2002 Donmoyer CM, Lacy DB, Zhang Y, Chen SS, McGuinness OP. Impact of chronic fructose infusion on hepatic metabolism during TPN administration. American Journal of Physiology. Endocrinology and Metabolism. 283: E1151-8. PMID 12424103 DOI: 10.1152/Ajpendo.00223.2001  0.82
2002 Chen SS, Donmoyer CM, Ejiofor J, McCay J, Archuletta R, Lacy DB, McGuinness OP. Impact of intraportal N(omega)-nitro-L-arginine infusion on hepatic glucose metabolism in total parenteral nutrition-adapted dogs: interaction with infection. Metabolism: Clinical and Experimental. 51: 274-83. PMID 11887160 DOI: 10.1053/Meta.2002.30501  0.827
2002 Cherrington AD, Sindelar D, Edgerton D, Steiner K, McGuinness OP. Physiological consequences of phasic insulin release in the normal animal. Diabetes. 51: S103-8. PMID 11815467  0.521
2001 Donmoyer CM, Ejiofor J, Lacy DB, Chen SS, McGuinness OP. Fructose augments infection-impaired net hepatic glucose uptake during TPN administration. American Journal of Physiology. Endocrinology and Metabolism. 280: E703-11. PMID 11287352 DOI: 10.1152/Ajpendo.2001.280.5.E703  0.83
2000 Chen SS, Donmoyer C, Zhang Y, Hande SA, Lacy DB, McGuinness OP. Impact of enteral and parenteral nutrition on hepatic and muscle glucose metabolism. Jpen. Journal of Parenteral and Enteral Nutrition. 24: 255-60. PMID 11011779 DOI: 10.1177/0148607100024005255  0.826
2000 Donmoyer CM, Chen SS, Hande SA, Lacy DB, Ejiofor J, McGuinness OP. Hyperinsulinemia compensates for infection-induced impairment in net hepatic glucose uptake during TPN. American Journal of Physiology. Endocrinology and Metabolism. 279: E235-43. PMID 10913021  0.84
2000 McGuinness OP, Ejiofor J, Lacy DB, Schrom N. Hepatic glucose metabolism during intraduodenal glucose infusion: impact of infection. American Journal of Physiology. Endocrinology and Metabolism. 279: E108-15. PMID 10893329 DOI: 10.1152/AJPENDO.2000.279.1.E108  0.605
1999 McGuinness OP, Snowden RT, Moran C, Neal DW, Fujiwara T, Cherrington AD. Impact of acute epinephrine removal on hepatic glucose metabolism during stress hormone infusion. Metabolism: Clinical and Experimental. 48: 910-4. PMID 10421235 DOI: 10.1016/S0026-0495(99)90228-7  0.598
1998 Lang CH, Frost RA, Ejiofor J, Lacy DB, McGuinness OP. Hepatic production and intestinal uptake of IGF-I: response to infection. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G1291-G1298. PMID 29585795 DOI: 10.1152/ajpgi.1998.275.6.G1291  0.385
1998 McGuinness OP, Ejiofor J, Audoly LP, Schrom N. Regulation of glucose production by NEFA and gluconeogenic precursors during chronic glucagon infusion. American Journal of Physiology. Endocrinology and Metabolism. 275: E432-E439. PMID 29585548 DOI: 10.1152/ajpendo.1998.275.3.E432  0.499
1998 McGuinness OP, Donmoyer C, Ejiofor J, McElligott S, Lacy DB. Hepatic and muscle glucose metabolism during total parenteral nutrition: impact of infection. American Journal of Physiology. Endocrinology and Metabolism. 275: E763-E769. PMID 29585223 DOI: 10.1152/ajpendo.1998.275.5.E763  0.807
1998 Meinz H, Lacy DB, Ejiofor J, McGuinness OP. Alterations in hepatic gluconeogenic amino acid uptake and gluconeogenesis in the endotoxin treated conscious dog. Shock (Augusta, Ga.). 9: 296-303. PMID 9565259 DOI: 10.1097/00024382-199804000-00010  0.569
1998 McGuinness O, Ejiofor J, Lacy D, Frost R, Lang C. HEPATIC AND INTESTINAL BALANCE FOR INSULINLIKE GROWTH FACTOR (IGF)-I DURING INFECTION. Shock. 9: 30-31. DOI: 10.1097/00024382-199806001-00102  0.362
1997 McGuinness OP, Shau V, Benson EM, Lewis M, Snowden RT, Greene JE, Neal DW, Cherrington AD. Role of epinephrine and norepinephrine in the metabolic response to stress hormone infusion in the conscious dog. American Journal of Physiology. Endocrinology and Metabolism. 273: E674-E681. PMID 29585247 DOI: 10.1152/ajpendo.1997.273.4.E674  0.412
1997 McGuinness OP, Mari A. Assessment of insulin action on glucose uptake and production during a euglycemic-hyperinsulinemic clamp in dog: a new kinetic analysis. Metabolism: Clinical and Experimental. 46: 1116-27. PMID 9322792 DOI: 10.1016/S0026-0495(97)90202-X  0.529
1996 McGuinness OP, Lacy DB, Eliasson K. Hyperglucagonemia and hepatic glucose metabolism during infection in the conscious dog. The American Journal of Physiology. 270: E580-8. PMID 8928762 DOI: 10.1152/ajpendo.1996.270.4.E580  0.527
1996 Fujiwara T, Cherrington AD, Neal DN, McGuinness OP. Role of cortisol in the metabolic response to stress hormone infusion in the conscious dog. Metabolism: Clinical and Experimental. 45: 571-8. PMID 8622599 DOI: 10.1016/S0026-0495(96)90026-8  0.42
1996 McGuinness OP, Ejiofor J, Schrom N. Interaction of non esterified fatty acids (NEFA) and gluconeogenic (GNG) precursor supply in regulating hepatic glucose production (HGP) during infection Shock. 5: 54. DOI: 10.1097/00024382-199606002-00173  0.413
1995 McGuinness OP, Lacy DB, Anderson J. Effect of acute glucagon removal on metabolic response to infection in conscious dog. The American Journal of Physiology. 268: E92-9. PMID 7840188 DOI: 10.1152/ajpendo.1995.268.1.E92  0.599
1995 McGuinness OP. The impact of infection on gluconeogenesis in the conscious dog. Shock (Augusta, Ga.). 2: 336-43. PMID 7743359 DOI: 10.1097/00024382-199411000-00007  0.56
1995 McGuinness OP, Jacobs J, Moran C, Lacy B. Impact of infection on hepatic disposal of a peripheral glucose infusion in the conscious dog. The American Journal of Physiology. 269: E199-207. PMID 7653536 DOI: 10.1152/ajpendo.1995.269.2.E199  0.627
1995 McGuinness OP, Meinz H, Schrom N. HEPATIC CARBOHYDRATE METABOLISM DURING INTRAPORTAL ENDOTOXIN INFUSION IN DOG Shock. 3: 40. DOI: 10.1097/00024382-199506000-00141  0.342
1994 McGuinness OP, Burgin K, Moran C, Bracy D, Cherrington AD. Role of glucagon in the metabolic response to stress hormone infusion in the conscious dog. The American Journal of Physiology. 266: E438-47. PMID 8166265 DOI: 10.1152/ajpendo.1994.266.3.E438  0.49
1994 McGuinness OP, Murrell S, Moran C, Bracy D, Cherrington AD. The effect of acute glucagon removal on the metabolic response to stress hormone infusion in the conscious dog. Metabolism: Clinical and Experimental. 43: 1310-7. PMID 7934986 DOI: 10.1016/0026-0495(94)90228-3  0.54
1994 McGuinness O. The Assessment of Insulin ActionIn Vivo: Methodological Considerations Seminars in Reproductive Medicine. 12: 143-148. DOI: 10.1055/s-2007-1016394  0.359
1994 Mari A, McGuinness OP. A Circulatory Model for Assessing Non-Steady-State Glucose Kinetics During a Euglycemic Clamp Ifac Proceedings Volumes. 27: 293-294. DOI: 10.1016/s1474-6670(17)46242-2  0.352
1993 Goldstein RE, Wasserman DH, McGuinness OP, Lacy DB, Cherrington AD, Abumrad NN. Effects of chronic elevation in plasma cortisol on hepatic carbohydrate metabolism. The American Journal of Physiology. 264: E119-27. PMID 8430780 DOI: 10.1152/ajpendo.1993.264.1.E119  0.559
1993 McGuinness OP, Fugiwara T, Murrell S, Bracy D, Neal D, O'Connor D, Cherrington AD. Impact of chronic stress hormone infusion on hepatic carbohydrate metabolism in the conscious dog. The American Journal of Physiology. 265: E314-22. PMID 8368302 DOI: 10.1152/ajpendo.1993.265.2.E314  0.585
1991 Myers SR, McGuinness OP, Neal DW, Cherrington AD. Intraportal glucose delivery alters the relationship between net hepatic glucose uptake and the insulin concentration. The Journal of Clinical Investigation. 87: 930-9. PMID 1999501 DOI: 10.1172/jci115100  0.588
1991 Cherrington AD, Pagliassotti MJ, Myers SR, Adkins-Marshall B, Mcguinness OP. Factors Which Regulate Net Hepatic Glucose Uptake In Vivo Journal of Parenteral and Enteral Nutrition. 15: 71S-73S. PMID 1865561 DOI: 10.1177/014860719101500371S  0.582
1990 McGuinness OP, Friedman A, Cherrington AD. Intraportal hyperinsulinemia decreases insulin-stimulated glucose uptake in the dog. Metabolism: Clinical and Experimental. 39: 127-32. PMID 2405232 DOI: 10.1016/0026-0495(90)90064-J  0.471
1990 McGuinness OP, Myers SR, Neal D, Cherrington AD. Chronic hyperinsulinemia decreases insulin action but not insulin sensitivity. Metabolism: Clinical and Experimental. 39: 931-7. PMID 2202884 DOI: 10.1016/0026-0495(90)90303-T  0.506
1988 Mari A, Cobelli C, Cherrington A, McGuinness O. A Model for the Study of Glucose Kinetics in Non-Steady State Ifac Proceedings Volumes. 21: 357-362. DOI: 10.1016/S1474-6670(17)57580-1  0.357
1987 McGuinness OP, Green DR, Cherrington AD. Glyburide sensitizes perfused rat liver to insulin-induced suppression of glucose output. Diabetes. 36: 472-6. PMID 3102299 DOI: 10.2337/diab.36.4.472  0.545
1987 Cobelli C, Mari A, Toffolo G, Cherrington A, McGuinness O. Dynamic Control of Insulin on Glucose Kinetics: Tracer Experiment Design and Time-Varying Interpretative Models Ifac Proceedings Volumes. 20: 25-30. DOI: 10.1016/S1474-6670(17)55237-4  0.423
1984 McGuinness OP, Spitzer JJ. Hepatic glycerol flux after E. coli endotoxin administration. The American Journal of Physiology. 247: R687-92. PMID 6388350 DOI: 10.1152/ajpregu.1984.247.4.R687  0.422
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