| Year |
Citation |
Score |
| 2024 |
Gimblet CJ, Ernst JW, Bell B, Bos KD, Stroud AK, Wendt LH, Donato AJ, Jalal DI, Pierce GL. Effect of Glycocalyx-targeted Therapy on Vascular Function in Older Adults: A Randomized Controlled Trial. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 38722754 DOI: 10.1152/japplphysiol.00150.2024 |
0.302 |
|
| 2024 |
Islam MT, Cai J, Allen S, Moreno DG, Bloom SI, Bramwell RC, Mitton J, Horn AG, Zhu W, Donato AJ, Holland WL, Lesniewski LA. Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 38545783 DOI: 10.1161/ATVBAHA.123.319375 |
0.61 |
|
| 2023 |
Gimblet CJ, Ernst JW, Bos KD, Stroud AK, Donato AJ, Jalal DI, Pierce GL. Effect of acute heparin administration on glycocalyx thickness and endothelial function in healthy younger adults. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 38126088 DOI: 10.1152/japplphysiol.00767.2023 |
0.34 |
|
| 2023 |
Islam MT, Hall SA, Dutson T, Bloom SI, Bramwell RC, Kim J, Tucker JR, Machin DR, Donato AJ, Lesniewski LA. Endothelial cell-specific reduction in mTOR ameliorates age-related arterial and metabolic dysfunction. Aging Cell. e14040. PMID 38017701 DOI: 10.1111/acel.14040 |
0.712 |
|
| 2023 |
Bloom SI, Tucker JR, Machin DR, Abdeahad H, Adeyemo AO, Thomas TG, Bramwell RC, Lesniewski LA, Donato AJ. Reduction of double-strand DNA break repair exacerbates vascular aging. Aging. 15: 9913-9947. PMID 37787989 DOI: 10.18632/aging.205066 |
0.675 |
|
| 2023 |
Bloom SI, Liu Y, Tucker JR, Islam MT, Machin DR, Abdeahad H, Thomas TG, Bramwell RC, Lesniewski LA, Donato AJ. Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments. Aging Cell. e13875. PMID 37259606 DOI: 10.1111/acel.13875 |
0.681 |
|
| 2023 |
Islam MT, Cai J, Allen S, Moreno DG, Bloom SI, Bramwell RC, Mitton J, Horn AG, Zhu W, Donato AJ, Holland WL, Lesniewski LA. Endothelial specific reduction in Arf6 impairs insulin-stimulated vasodilation and skeletal muscle blood flow resulting in systemic insulin resistance. Biorxiv : the Preprint Server For Biology. PMID 37205339 DOI: 10.1101/2023.05.02.539173 |
0.605 |
|
| 2023 |
Gogulamudi VR, Islam MT, Durrant JR, Adeyemo AO, Trott DW, Hyuhn MH, Zhu W, Donato AJ, Walker AE, Lesniewski LA. Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis. Plos One. 18: e0285253. PMID 37163513 DOI: 10.1371/journal.pone.0285253 |
0.74 |
|
| 2023 |
Machin DR, Trott DW, Gogulamudi VR, Islam MT, Bloom SI, Vink H, Lesniewski LA, Donato AJ. Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction. Geroscience. PMID 36787090 DOI: 10.1007/s11357-023-00745-1 |
0.686 |
|
| 2023 |
Islam MT, Tuday E, Allen S, Kim J, Trott DW, Holland WL, Donato AJ, Lesniewski LA. Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age. Aging Cell. e13767. PMID 36637079 DOI: 10.1111/acel.13767 |
0.654 |
|
| 2022 |
Bloom SI, Tucker JR, Lim J, Thomas TG, Stoddard GJ, Lesniewski LA, Donato AJ. Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions. Geroscience. PMID 36350415 DOI: 10.1007/s11357-022-00681-6 |
0.653 |
|
| 2022 |
Bloom SI, Islam MT, Lesniewski LA, Donato AJ. Mechanisms and consequences of endothelial cell senescence. Nature Reviews. Cardiology. PMID 35853997 DOI: 10.1038/s41569-022-00739-0 |
0.643 |
|
| 2022 |
Gogulamudi VR, Machin DR, Henson GD, Lim J, Bramwell RC, Durrant JR, Donato AJ, Lesniewski LA. Sirt1 overexpression attenuates Western-style diet-induced aortic stiffening in mice. Physiological Reports. 10: e15284. PMID 35561022 DOI: 10.14814/phy2.15284 |
0.656 |
|
| 2021 |
Pierce GL, Coutinho TA, DuBose LE, Donato AJ. Is It Good to Have a Stiff Aorta with Aging? Causes and Consequences. Physiology (Bethesda, Md.). PMID 34779281 DOI: 10.1152/physiol.00035.2021 |
0.312 |
|
| 2021 |
Trott DW, Machin DR, Phuong TT, Adeyemo AO, Bloom SI, Bramwell RC, Sorensen ES, Lesniewski LA, Donato AJ. T cells mediate cell non-autonomous arterial aging in mice. The Journal of Physiology. PMID 34164826 DOI: 10.1113/JP281698 |
0.658 |
|
| 2021 |
Trott DW, Islam MT, Buckley DJ, Donato AJ, Dutson T, Sorensen ES, Cai J, Gogulamudi VR, Phuong TTT, Lesniewski LA. T lymphocyte depletion ameliorates age-related metabolic impairments in mice. Geroscience. PMID 33893902 DOI: 10.1007/s11357-021-00368-4 |
0.605 |
|
| 2020 |
Islam MT, Henson GD, Machin DR, Bramwell RC, Donato AJ, Lesniewski LA. Aging differentially impacts vasodilation and angiogenesis in arteries from the white and brown adipose tissues. Experimental Gerontology. 142: 111126. PMID 33203620 DOI: 10.1016/j.exger.2020.111126 |
0.706 |
|
| 2020 |
Machin DR, Auduong Y, Gogulamudi VR, Liu Y, Islam MT, Lesniewski LA, Donato AJ. Lifelong SIRT-1 overexpression attenuates large artery stiffening with advancing age. Aging. 12. PMID 32564006 DOI: 10.18632/aging.103322 |
0.656 |
|
| 2020 |
Dutson T, Islam MT, Cai J, Sun Z, Fang D, Donato AJ, Zhu W, Lesniewski LA. Arf6 Heterozygosity Results in Impaired Glucose Tolerance Due to Abberant Hepatic Gluconeogenesis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09478 |
0.582 |
|
| 2020 |
Bramwell RC, Bloom SI, Machin DR, Lesniewski LA, Donato AJ. Genetic Reduction of DNA Damage Repair Protein ATM Kinase Attenuates Endothelium‐Dependent Dilation and NO Bioavailability via Enhanced Superoxide in Old but not Young Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06559 |
0.618 |
|
| 2020 |
Tucker JR, Machin DR, Walker AE, Frech TM, Donato AJ. Autoantibody Subtype does not Impact Peripheral Endothelial Function and Hemodynamics in Systemic Sclerosis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06528 |
0.543 |
|
| 2020 |
Gogulamudi VR, Durrant JR, Donato AJ, Lesniewski LA. Aging exacerbates spontaneous atherosclerosis in apolipoprotein E deficient mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06010 |
0.655 |
|
| 2020 |
Islam MT, Cai J, Tucker JR, Mitton J, Zhu W, Donato AJ, Lesniewski LA. Endothelial Cell‐Specific Deletion of Small GTPase ARF6 Results in Blunted Insulin‐Stimulated Vasodilation and Systemic Insulin Resistance via Arf6/Akt/eNOS Signaling Pathway The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04569 |
0.625 |
|
| 2020 |
Bloom SI, Islam MT, Tucker JR, Phuong T, Sorensen E, Cai J, Lesniewski LA, Donato AJ. Induction of Telomere Uncapping in Adipocytes Results in Cellular Senescence and Metabolic Dysfunction The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03353 |
0.601 |
|
| 2020 |
Machin DR, Auduong Y, Liu Y, Gogulamudi VR, Islam MT, Lesniewski LA, Donato AJ. Lifelong SIRT‐1 Overexpression Attenuates Aortic Stiffening with Advancing Age The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02675 |
0.656 |
|
| 2019 |
Machin DR, Phuong TT, Donato AJ. The role of the endothelial glycocalyx in advanced age and cardiovascular disease. Current Opinion in Pharmacology. 45: 66-71. PMID 31112922 DOI: 10.1016/J.Coph.2019.04.011 |
0.468 |
|
| 2019 |
Phuong TTT, Walker AE, Henson GD, Machin DR, Li DY, Donato AJ, Lesniewski LA. Deletion of Robo4 prevents high fat diet induced adipose artery and systemic metabolic dysfunction. Microcirculation (New York, N.Y. : 1994). e12540. PMID 30825241 DOI: 10.1111/Micc.12540 |
0.734 |
|
| 2019 |
Walker AE, Breevoort SR, Durrant JR, Liu Y, Machin DR, Dobson PS, Nielson EI, Meza AJ, Islam MT, Donato AJ, Lesniewski LA. The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age. Scientific Reports. 9: 2925. PMID 30814657 DOI: 10.1038/S41598-019-39466-X |
0.779 |
|
| 2019 |
Walker AE, Kronquist EK, Chinen KT, Reihl KD, Li DY, Lesniewski LA, Donato AJ. Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness. Experimental Physiology. PMID 30633428 DOI: 10.1113/Ep087453 |
0.736 |
|
| 2019 |
Machin DR, Nguyen D, Bramwell RC, Lesniewski LA, Donato AJ. Dietary Glycocalyx Precursor Supplementation Ameliorates Age‐Related Vascular Dysfunction The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.828.1 |
0.719 |
|
| 2018 |
Hazra S, Henson GD, Bramwell RC, Donato AJ, Lesniewski LA. Impact of High Fat Diet on Vasoconstrictor Reactivity of White and Brown Adipose Tissue Resistance Arteries. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30550353 DOI: 10.1152/Ajpheart.00278.2018 |
0.678 |
|
| 2018 |
Garrett Morgan R, Walker AE, Trott DW, Machin DR, Henson GD, Reihl KD, Cawthon RM, Denchi EL, Liu Y, Bloom SI, Phuong TT, Richardson RS, Lesniewski LA, Donato AJ. Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress. Journal of Molecular and Cellular Cardiology. PMID 30502348 DOI: 10.1016/J.Yjmcc.2018.11.014 |
0.792 |
|
| 2018 |
Ungvari Z, Tarantini S, Donato AJ, Galvan V, Csiszar A. Mechanisms of Vascular Aging. Circulation Research. 123: 849-867. PMID 30355080 DOI: 10.1161/Circresaha.118.311378 |
0.452 |
|
| 2018 |
Donato AJ, Machin DR, Lesniewski LA. Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease. Circulation Research. 123: 825-848. PMID 30355078 DOI: 10.1161/Circresaha.118.312563 |
0.715 |
|
| 2018 |
Liu Y, Bloom SI, Donato AJ. The Role of Senescence, Telomere Dysfunction and Shelterin in Vascular Aging. Microcirculation (New York, N.Y. : 1994). e12487. PMID 29924435 DOI: 10.1111/Micc.12487 |
0.488 |
|
| 2018 |
Clifton HL, Machin DR, Groot HJ, Frech TM, Donato AJ, Richardson RS, Wray DW. Attenuated nitric oxide bioavailability in systemic sclerosis: Evidence from the novel assessment of passive leg movement. Experimental Physiology. PMID 29790215 DOI: 10.1113/Ep086991 |
0.36 |
|
| 2018 |
Machin DR, Bloom SI, Campbell RA, Phuong TTT, Gates PE, Lesniewski LA, Rondina MT, Donato AJ. Advanced age results in a diminished endothelial glycocalyx. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29750566 DOI: 10.1152/Ajpheart.00104.2018 |
0.709 |
|
| 2018 |
Morgan RG, Donato AJ, Walker AE. Telomere uncapping and vascular aging. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29547021 DOI: 10.1152/Ajpheart.00008.2018 |
0.598 |
|
| 2017 |
Rossman MJ, Kaplon RE, Hill SD, McNamara MN, Santos-Parker JR, Pierce GL, Seals DR, Donato AJ. Endothelial Cell Senescence with Aging in Healthy Humans: Prevention by Habitual Exercise and Relation to Vascular Endothelial Function. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00416.2017. PMID 28971843 DOI: 10.1152/Ajpheart.00416.2017 |
0.626 |
|
| 2017 |
Trott DW, Lesniewski LA, Donato AJ. Selected life-extending interventions reduce arterial CXCL10 and macrophage colony-stimulating factor in aged mouse arteries. Cytokine. 96: 102-106. PMID 28390264 DOI: 10.1016/J.Cyto.2017.03.008 |
0.7 |
|
| 2017 |
Morgan RG, Venturelli M, Gross C, Tarperi C, Schena F, Reggiani C, Naro F, Pedrinolla A, Monaco L, Richardson RS, Donato AJ. Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study. Plos One. 12: e0169628. PMID 28060910 DOI: 10.1371/Journal.Pone.0169628 |
0.347 |
|
| 2016 |
Trott DW, Henson GD, Ho MH, Allison SA, Lesniewski LA, Donato AJ. Age-related arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise. Experimental Gerontology. PMID 28012941 DOI: 10.1016/J.Exger.2016.12.016 |
0.662 |
|
| 2016 |
Machin DR, Leary ME, He Y, Shiu YT, Tanaka H, Donato AJ. Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats. Journal of Visualized Experiments : Jove. PMID 27842366 DOI: 10.3791/54762 |
0.367 |
|
| 2016 |
Bell ED, Donato AJ, Monson KL. Cerebrovascular dysfunction following subfailure axial stretch. Journal of the Mechanical Behavior of Biomedical Materials. 65: 627-633. PMID 27736719 DOI: 10.1016/J.Jmbbm.2016.09.028 |
0.333 |
|
| 2016 |
Machin DR, Clifton HL, Garten RS, Gifford JR, Richardson RS, Wray DW, Frech TM, Donato AJ. Exercise-Induced Brachial Artery Blood Flow and Vascular Function is Impaired in Systemic Sclerosis. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00547.2016. PMID 27694218 DOI: 10.1152/Ajpheart.00547.2016 |
0.443 |
|
| 2016 |
Lesniewski LA, Seals DR, Walker AE, Henson GD, Blimline MW, Trott DW, Bosshardt GC, LaRocca TJ, Lawson BR, Zigler MC, Donato AJ. Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. Aging Cell. PMID 27660040 DOI: 10.1111/Acel.12524 |
0.832 |
|
| 2016 |
Hazra S, Henson GD, Morgan RG, Breevoort SR, Ives SJ, Richardson RS, Donato AJ, Lesniewski LA. Experimental reduction of miR-92a mimics arterial aging. Experimental Gerontology. PMID 27523918 DOI: 10.1016/J.Exger.2016.08.007 |
0.667 |
|
| 2016 |
Davizon-Castillo P, Ashworth K, Higa K, Hernandez G, Acharya S, Campbell RA, Rondina M, Collins CB, Donato A, Lesniewski L, DeGregori J, Holer M, Banda N, Di Paola J, Pietras EM. Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging Blood. 128: 3747-3747. DOI: 10.1182/Blood.V128.22.3747.3747 |
0.623 |
|
| 2015 |
Walker AE, Garrett Morgan R, Ives SJ, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ. Age-related arterial telomere uncapping and senescence is greater in women compared with men. Experimental Gerontology. PMID 26602606 DOI: 10.1016/J.Exger.2015.11.009 |
0.75 |
|
| 2015 |
Trinity JD, Barrett-O'Keefe Z, Ives SJ, Morgan G, Rossman MJ, Donato AJ, Runnels S, Morgan DE, Gmelch BS, Bledsoe AD, Richardson RS, Wray DW. Endogenous endothelin-1 and femoral artery shear rate: impact of age and implications for atherosclerosis. Journal of Hypertension. PMID 26599223 DOI: 10.1097/Hjh.0000000000000777 |
0.388 |
|
| 2015 |
Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY. Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium. Plos One. 10: e0140370. PMID 26469335 DOI: 10.1371/Journal.Pone.0140370 |
0.69 |
|
| 2015 |
Jablonski KL, Donato AJ, Fleenor BS, Nowlan MJ, Walker AE, Kaplon RE, Ballak DB, Seals DR. Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor κ B signalling. Journal of Hypertension. PMID 26378681 DOI: 10.1097/Hjh.0000000000000742 |
0.808 |
|
| 2015 |
Tajbakhsh S, Aliakbari K, Hussey DJ, Lower KM, Donato AJ, Sokoya EM. Differential Telomere Shortening in Blood versus Arteries in an Animal Model of Type 2 Diabetes. Journal of Diabetes Research. 2015: 153829. PMID 26346823 DOI: 10.1155/2015/153829 |
0.43 |
|
| 2015 |
Donato AJ, Morgan RG, Walker AE, Lesniewski LA. Cellular and molecular biology of aging endothelial cells. Journal of Molecular and Cellular Cardiology. PMID 25655936 DOI: 10.1016/J.Yjmcc.2015.01.021 |
0.781 |
|
| 2015 |
Ghosh P, Mora Solis FR, Dominguez JM, Spier SA, Donato AJ, Delp MD, Muller-Delp JM. Exercise training reverses aging-induced impairment of myogenic constriction in skeletal muscle arterioles. Journal of Applied Physiology (Bethesda, Md. : 1985). 118: 904-11. PMID 25634999 DOI: 10.1152/Japplphysiol.00277.2014 |
0.785 |
|
| 2015 |
Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ. Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness. The Journal of Physiology. 593: 1931-43. PMID 25627876 DOI: 10.1113/Jphysiol.2014.285338 |
0.763 |
|
| 2015 |
Frech T, Walker AE, Barrett-O'Keefe Z, Hopkins PN, Richardson RS, Wray DW, Donato AJ. Systemic sclerosis induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction. Clinical Rheumatology. 34: 905-13. PMID 25511849 DOI: 10.1007/S10067-014-2834-5 |
0.634 |
|
| 2015 |
Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, et al. Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation. 131: 289-99. PMID 25486933 DOI: 10.1161/Circulationaha.114.010403 |
0.672 |
|
| 2015 |
Barrett-O'Keefe Z, Ives SJ, Trinity JD, Morgan G, Rossman MJ, Donato AJ, Runnels S, Morgan DE, Gmelch BS, Bledsoe AD, Richardson RS, Wray DW. Endothelin-A-mediated vasoconstriction during exercise with advancing age. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 554-65. PMID 24821105 DOI: 10.1093/Gerona/Glu065 |
0.419 |
|
| 2014 |
Gano LB, Donato AJ, Pasha HM, Hearon CM, Sindler AL, Seals DR. The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1754-63. PMID 25326534 DOI: 10.1152/Ajpheart.00377.2014 |
0.825 |
|
| 2014 |
Donato AJ, Henson GD, Hart CR, Layec G, Trinity JD, Bramwell RC, Enz RA, Morgan RG, Reihl KD, Hazra S, Walker AE, Richardson RS, Lesniewski LA. The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction. The Journal of Physiology. 592: 4083-96. PMID 25038241 DOI: 10.1113/Jphysiol.2014.274175 |
0.774 |
|
| 2014 |
Henson GD, Walker AE, Reihl KD, Donato AJ, Lesniewski LA. Dichotomous mechanisms of aortic stiffening in high-fat diet fed young and old B6D2F1 mice. Physiological Reports. 2: e00268. PMID 24760522 DOI: 10.1002/Phy2.268 |
0.751 |
|
| 2014 |
Venturelli M, Morgan GR, Donato AJ, Reese V, Bottura R, Tarperi C, Milanese C, Schena F, Reggiani C, Naro F, Cawthon RM, Richardson RS. Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age. Clinical Science (London, England : 1979). 127: 415-21. PMID 24708050 DOI: 10.1042/Cs20140051 |
0.369 |
|
| 2014 |
Morgan RG, Ives SJ, Walker AE, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ. Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping. Journal of Hypertension. 32: 1293-9. PMID 24686009 DOI: 10.1097/Hjh.0000000000000157 |
0.726 |
|
| 2014 |
Donato AJ, Lesniewski LA, Stuart D, Walker AE, Henson G, Sorensen L, Li D, Kohan DE. Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development. Life Sciences. 118: 238-43. PMID 24412386 DOI: 10.1016/J.Lfs.2013.12.209 |
0.739 |
|
| 2014 |
Walker AE, Henson GD, Reihl KD, Nielson EI, Morgan RG, Lesniewski LA, Donato AJ. Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries. Age (Dordrecht, Netherlands). 36: 559-69. PMID 24065292 DOI: 10.1007/S11357-013-9585-0 |
0.77 |
|
| 2013 |
Lesniewski LA, Zigler ML, Durrant JR, Nowlan MJ, Folian BJ, Donato AJ, Seals DR. Aging compounds western diet-associated large artery endothelial dysfunction in mice: prevention by voluntary aerobic exercise. Experimental Gerontology. 48: 1218-25. PMID 23954368 DOI: 10.1016/J.Exger.2013.08.001 |
0.768 |
|
| 2013 |
Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD, Henson GD, Lawson BR, Lesniewski LA, Seals DR. Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell. 12: 772-83. PMID 23714110 DOI: 10.1111/Acel.12103 |
0.802 |
|
| 2013 |
Morgan RG, Ives SJ, Lesniewski LA, Cawthon RM, Andtbacka RH, Noyes RD, Richardson RS, Donato AJ. Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries. American Journal of Physiology. Heart and Circulatory Physiology. 305: H251-8. PMID 23666675 DOI: 10.1152/Ajpheart.00197.2013 |
0.718 |
|
| 2013 |
Barrett-O'Keefe Z, Ives SJ, Trinity JD, Morgan G, Rossman MJ, Donato AJ, Runnels S, Morgan DE, Gmelch BS, Bledsoe AD, Richardson RS, Wray DW. Taming the "sleeping giant": the role of endothelin-1 in the regulation of skeletal muscle blood flow and arterial blood pressure during exercise. American Journal of Physiology. Heart and Circulatory Physiology. 304: H162-9. PMID 23103494 DOI: 10.1152/Ajpheart.00603.2012 |
0.362 |
|
| 2013 |
Kohan D, Lesniewski L, Donato A, Sorensen L, Li D, van Hoek A, Stuart D. Smooth muscle specific disruption of the endothelin A receptor in mice reduces arterial pressure and affects vascular development Life Sciences. 93: e71. DOI: 10.1016/J.Lfs.2014.01.038 |
0.676 |
|
| 2012 |
Park Y, Prisby RD, Behnke BJ, Dominguez JM, Lesniewski LA, Donato AJ, Muller-Delp J, Delp MD. Effects of aging, TNF-α, and exercise training on angiotensin II-induced vasoconstriction of rat skeletal muscle arterioles. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 1091-100. PMID 22923503 DOI: 10.1152/Japplphysiol.00292.2012 |
0.754 |
|
| 2012 |
Donato AJ, Henson GD, Morgan RG, Enz RA, Walker AE, Lesniewski LA. TNF-α impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity. American Journal of Physiology. Heart and Circulatory Physiology. 303: H672-9. PMID 22821989 DOI: 10.1152/Ajpheart.00271.2012 |
0.759 |
|
| 2012 |
Ives SJ, Andtbacka RHI, Park SY, Donato AJ, Gifford JR, Noyes RD, Lesniewski LA, Richardson RS. Human skeletal muscle feed arteries: Evidence of regulatory potential Acta Physiologica. 206: 135-141. PMID 22726882 DOI: 10.1111/J.1748-1716.2012.02464.X |
0.664 |
|
| 2012 |
Lesniewski LA, Zigler MC, Durrant JR, Donato AJ, Seals DR. Sustained activation of AMPK ameliorates age-associated vascular endothelial dysfunction via a nitric oxide-independent mechanism. Mechanisms of Ageing and Development. 133: 368-71. PMID 22484146 DOI: 10.1016/J.Mad.2012.03.011 |
0.778 |
|
| 2012 |
Rippe C, Blimline M, Magerko KA, Lawson BR, LaRocca TJ, Donato AJ, Seals DR. MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation. Experimental Gerontology. 47: 45-51. PMID 22037549 DOI: 10.1016/J.Exger.2011.10.004 |
0.707 |
|
| 2011 |
Pierce GL, Donato AJ, LaRocca TJ, Eskurza I, Silver AE, Seals DR. Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress. Aging Cell. 10: 1032-7. PMID 21943306 DOI: 10.1111/J.1474-9726.2011.00748.X |
0.801 |
|
| 2011 |
Donato AJ, Magerko KA, Lawson BR, Durrant JR, Lesniewski LA, Seals DR. SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans. The Journal of Physiology. 589: 4545-54. PMID 21746786 DOI: 10.1113/Jphysiol.2011.211219 |
0.794 |
|
| 2011 |
Lesniewski LA, Durrant JR, Connell ML, Henson GD, Black AD, Donato AJ, Seals DR. Aerobic exercise reverses arterial inflammation with aging in mice. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1025-32. PMID 21622824 DOI: 10.1152/Ajpheart.01276.2010 |
0.771 |
|
| 2011 |
Gano LB, Donato AJ, Pierce GL, Pasha HM, Magerko KA, Roeca C, Seals DR. Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise. Physiological Genomics. 43: 895-902. PMID 21610086 DOI: 10.1152/Physiolgenomics.00204.2010 |
0.805 |
|
| 2011 |
Seals DR, Jablonski KL, Donato AJ. Aging and vascular endothelial function in humans. Clinical Science (London, England : 1979). 120: 357-75. PMID 21244363 DOI: 10.1042/Cs20100476 |
0.813 |
|
| 2011 |
Wray DW, Nishiyama SK, Donato AJ, Carlier P, Bailey DM, Uberoi A, Richardson RS. The paradox of oxidative stress and exercise with advancing age. Exercise and Sport Sciences Reviews. 39: 68-76. PMID 21206280 DOI: 10.1097/Jes.0B013E31820D7657 |
0.388 |
|
| 2010 |
Edwards AG, Donato AJ, Lesniewski LA, Gioscia RA, Seals DR, Moore RL. Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK. Mechanisms of Ageing and Development. 131: 739-42. PMID 20934448 DOI: 10.1016/J.Mad.2010.09.007 |
0.695 |
|
| 2010 |
Wray DW, Nishiyama SK, Donato AJ, Richardson RS. Human vascular aging: Limb-specific lessons Exercise and Sport Sciences Reviews. 38: 177-185. PMID 20871234 DOI: 10.1097/Jes.0B013E3181F45413 |
0.401 |
|
| 2010 |
Rippe C, Lesniewski L, Connell M, LaRocca T, Donato A, Seals D. Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress. Aging Cell. 9: 304-12. PMID 20121721 DOI: 10.1111/J.1474-9726.2010.00557.X |
0.83 |
|
| 2010 |
Walker AE, Seibert SM, Donato AJ, Pierce GL, Seals DR. Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults. Hypertension. 55: 363-9. PMID 20048194 DOI: 10.1161/Hypertensionaha.109.145870 |
0.706 |
|
| 2010 |
Donato AJ, Uberoi A, Bailey DM, Wray DW, Richardson RS. Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men. American Journal of Physiology. Heart and Circulatory Physiology. 298: H671-8. PMID 19966056 DOI: 10.1152/Ajpheart.00761.2009 |
0.414 |
|
| 2010 |
Silver AE, Christou DD, Donato AJ, Beske SD, Moreau KL, Magerko KA, Seals DR. Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins. Journal of Vascular Research. 47: 1-8. PMID 19672102 DOI: 10.1159/000231715 |
0.775 |
|
| 2009 |
Donato AJ, Pierce GL, Lesniewski LA, Seals DR. Role of NFkappaB in age-related vascular endothelial dysfunction in humans. Aging. 1: 678-80. PMID 20157550 |
0.72 |
|
| 2009 |
Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K, Seals DR. Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. American Journal of Physiology. Heart and Circulatory Physiology. 297: H425-32. PMID 19465546 DOI: 10.1152/Ajpheart.00689.2008 |
0.823 |
|
| 2009 |
Durrant JR, Seals DR, Connell ML, Russell MJ, Lawson BR, Folian BJ, Donato AJ, Lesniewski LA. Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase. The Journal of Physiology. 587: 3271-85. PMID 19417091 DOI: 10.1113/Jphysiol.2009.169771 |
0.772 |
|
| 2009 |
Lesniewski LA, Connell ML, Durrant JR, Folian BJ, Anderson MC, Donato AJ, Seals DR. B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 9-20. PMID 19211548 DOI: 10.1093/Gerona/Gln049 |
0.76 |
|
| 2008 |
Donato AJ, Black AD, Jablonski KL, Gano LB, Seals DR. Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell. 7: 805-12. PMID 18782346 DOI: 10.1111/J.1474-9726.2008.00438.X |
0.802 |
|
| 2008 |
Donato AJ, Eskurza I, Jablonski KL, Gano LB, Pierce GL, Seals DR. Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1359-63. PMID 18669935 DOI: 10.1152/Japplphysiol.90629.2008 |
0.806 |
|
| 2008 |
Seals DR, Desouza CA, Donato AJ, Tanaka H. Habitual exercise and arterial aging. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1323-32. PMID 18583377 DOI: 10.1152/Japplphysiol.90553.2008 |
0.642 |
|
| 2008 |
Pierce GL, Beske SD, Lawson BR, Southall KL, Benay FJ, Donato AJ, Seals DR. Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults. Hypertension. 52: 72-9. PMID 18504322 DOI: 10.1161/Hypertensionaha.108.111427 |
0.565 |
|
| 2008 |
Colleran PN, Behnke BJ, Wilkerson MK, Donato AJ, Delp MD. Simulated microgravity alters rat mesenteric artery vasoconstrictor dynamics through an intracellular Ca(2+) release mechanism. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R1577-85. PMID 18353882 DOI: 10.1152/Ajpregu.00084.2008 |
0.589 |
|
| 2008 |
Lesniewski LA, Donato AJ, Behnke BJ, Woodman CR, Laughlin MH, Ray CA, Delp MD. Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1840-50. PMID 18245568 DOI: 10.1152/Ajpheart.00692.2007 |
0.702 |
|
| 2007 |
Jablonski KL, Seals DR, Eskurza I, Monahan KD, Donato AJ. High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men. Journal of Applied Physiology (Bethesda, Md. : 1985). 103: 1715-21. PMID 17965239 DOI: 10.1152/Japplphysiol.00533.2007 |
0.804 |
|
| 2007 |
Wray DW, Nishiyama SK, Donato AJ, Sander M, Wagner PD, Richardson RS. Endothelin-1-mediated vasoconstriction at rest and during dynamic exercise in healthy humans American Journal of Physiology - Heart and Circulatory Physiology. 293. PMID 17693542 DOI: 10.1152/Ajpheart.00867.2007 |
0.337 |
|
| 2007 |
Donato AJ. Ageing and vascular adrenoceptor desensitization: too little, too late? The Journal of Physiology. 582: 9-10. PMID 17540698 DOI: 10.1113/Jphysiol.2007.136218 |
0.44 |
|
| 2007 |
Donato AJ, Eskurza I, Silver AE, Levy AS, Pierce GL, Gates PE, Seals DR. Direct evidence of endothelial oxidative stress with aging in humans: relation to impaired endothelium-dependent dilation and upregulation of nuclear factor-kappaB. Circulation Research. 100: 1659-66. PMID 17478731 DOI: 10.1161/01.Res.0000269183.13937.E8 |
0.784 |
|
| 2007 |
Prisby RD, Ramsey MW, Behnke BJ, Dominguez JM, Donato AJ, Allen MR, Delp MD. Aging reduces skeletal blood flow, endothelium-dependent vasodilation, and NO bioavailability in rats. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1280-8. PMID 17451371 DOI: 10.1359/Jbmr.070415 |
0.774 |
|
| 2007 |
Seals DR, Donato AJ, Pierce GL, Walker AE. Commentary on Viewpoint "Human experimentation: no accurate, quantitative data?". Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 1294. PMID 17341743 DOI: 10.1152/japplphysiol.01301.2006 |
0.53 |
|
| 2007 |
Silver AE, Beske SD, Christou DD, Donato AJ, Moreau KL, Eskurza I, Gates PE, Seals DR. Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress. Circulation. 115: 627-37. PMID 17242275 DOI: 10.1161/Circulationaha.106.657486 |
0.748 |
|
| 2007 |
Richardson RS, Donato AJ, Uberoi A, Wray DW, Lawrenson L, Nishiyama S, Bailey DM. Exercise-induced brachial artery vasodilation: role of free radicals. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1516-22. PMID 17114239 DOI: 10.1152/Ajpheart.01045.2006 |
0.376 |
|
| 2007 |
Wray DW, Donato AJ, Nishiyama SK, Richardson RS. Acute sympathetic vasoconstriction at rest and during dynamic exercise in cyclists and sedentary humans Journal of Applied Physiology. 102: 704-712. PMID 17082367 DOI: 10.1152/Japplphysiol.00984.2006 |
0.319 |
|
| 2007 |
Donato AJ, Lesniewski LA, Delp MD. Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles. The Journal of Physiology. 579: 115-25. PMID 17082231 DOI: 10.1113/Jphysiol.2006.120055 |
0.751 |
|
| 2007 |
Walker AE, Donato AJ, Eskurza I, Pierce GL, Silver AE, Seals DR. Plasma low‐density lipoprotein cholesterol modulates vascular endothelial function as well as systemic and vascular endothelial oxidative stress in middle‐aged and older men The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A445-A |
0.787 |
|
| 2006 |
Behnke BJ, Prisby RD, Lesniewski LA, Donato AJ, Olin HM, Delp MD. Influence of ageing and physical activity on vascular morphology in rat skeletal muscle. The Journal of Physiology. 575: 617-26. PMID 16644803 DOI: 10.1113/Jphysiol.2006.108431 |
0.766 |
|
| 2006 |
Donato AJ, Uberoi A, Wray DW, Nishiyama S, Lawrenson L, Richardson RS. Differential effects of aging on limb blood flow in humans American Journal of Physiology - Heart and Circulatory Physiology. 290. PMID 16183733 DOI: 10.1152/Ajpheart.00405.2005 |
0.378 |
|
| 2005 |
Wray DW, Donato AJ, Uberoi A, Merlone JP, Richardson RS. Onset exercise hyperaemia in humans: partitioning the contributors. The Journal of Physiology. 565: 1053-60. PMID 15860535 DOI: 10.1113/Jphysiol.2005.084327 |
0.327 |
|
| 2005 |
Donato AJ, Lesniewski LA, Delp MD. The effects of aging and exercise training on endothelin-1 vasoconstrictor responses in rat skeletal muscle arterioles. Cardiovascular Research. 66: 393-401. PMID 15820208 DOI: 10.1016/J.Cardiores.2004.10.023 |
0.769 |
|
| 2004 |
Spier SA, Delp MD, Meininger CJ, Donato AJ, Ramsey MW, Muller-Delp JM. Effects of ageing and exercise training on endothelium-dependent vasodilatation and structure of rat skeletal muscle arterioles. The Journal of Physiology. 556: 947-58. PMID 15004211 DOI: 10.1113/Jphysiol.2003.060301 |
0.801 |
|
| 2003 |
Moreau KL, Donato AJ, Seals DR, DeSouza CA, Tanaka H. Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women. Cardiovascular Research. 57: 861-8. PMID 12618248 DOI: 10.1016/S0008-6363(02)00777-0 |
0.555 |
|
| 2003 |
Moreau KL, Donato AJ, Tanaka H, Jones PP, Gates PE, Seals DR. Basal leg blood flow in healthy women is related to age and hormone replacement therapy status. The Journal of Physiology. 547: 309-16. PMID 12562958 DOI: 10.1113/Jphysiol.2002.032524 |
0.557 |
|
| 2003 |
Bell C, Monahan KD, Donato AJ, Hunt BE, Seals DR, Beck KC. Use of acetylene breathing to determine cardiac output in young and older adults. Medicine and Science in Sports and Exercise. 35: 58-64. PMID 12544636 DOI: 10.1097/00005768-200301000-00010 |
0.454 |
|
| 2003 |
Miyachi M, Donato AJ, Yamamoto K, Takahashi K, Gates PE, Moreau KL, Tanaka H. Greater age-related reductions in central arterial compliance in resistance-trained men. Hypertension. 41: 130-5. PMID 12511542 DOI: 10.1161/01.Hyp.0000047649.62181.88 |
0.428 |
|
| 2003 |
Donato AJ, Tench K, Glueck DH, Seals DR, Eskurza I, Tanaka H. Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance. Journal of Applied Physiology (Bethesda, Md. : 1985). 94: 764-9. PMID 12391125 DOI: 10.1152/Japplphysiol.00438.2002 |
0.53 |
|
| 2003 |
Moreau KL, Donato AJ, Tanaka H, Seals DR. REGULAR AEROBIC EXERCISE IS ASSOCIATED WITH REDUCED FEMORAL ARTERY INTIMA-MEDIA THICKNESS WITH AGE IN WOMEN Medicine & Science in Sports & Exercise. 35: S359. DOI: 10.1097/00005768-200305001-01994 |
0.561 |
|
| 2002 |
Moreau KL, Donato AJ, Seals DR, Dinenno FA, Blackett SD, Hoetzer GL, Desouza CA, Tanaka H. Arterial intima-media thickness: site-specific associations with HRT and habitual exercise. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1409-17. PMID 12234791 DOI: 10.1152/Ajpheart.00035.2002 |
0.703 |
|
| 2002 |
Eskurza I, Donato AJ, Moreau KL, Seals DR, Tanaka H. Changes in maximal aerobic capacity with age in endurance-trained women: 7-yr follow-up. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 2303-8. PMID 12015340 DOI: 10.1097/01823246-200213040-00010 |
0.495 |
|
| 2001 |
Bell C, Monahan KD, Donato AJ, Hunt BE, Seals DR, Beck KC. USE OF OPEN-CIRCUIT ACETYLENE BREATHING TO ESTIMATE SUB-MAXIMAL AND MAXIMAL CARDIAC OUTPUT Medicine & Science in Sports & Exercise. 33: S300. DOI: 10.1097/00005768-200105001-01690 |
0.399 |
|
| 2001 |
Eskurza I, Donato AJ, Moreau KL, Reiling MJ, Seals DR, Tanaka H. GREATER DECLINE IN MAXIMAL AEROBIC CAPACITY IN ENDURANCE-TRAINED VS. SEDENTARY WOMEN Medicine & Science in Sports & Exercise. 33: S125. DOI: 10.1097/00005768-200105001-00710 |
0.459 |
|
| 2001 |
Moreau KL, Donato AJ, Seals DR, Blackett SD, Hoetzer GL, DeSouza CA, Tanaka H. INFLUENCE OF HABITUAL EXERCISE AND HORMONE REPLACEMENT THERAPY ON CAROTID ARTERY IMTIMA-MEDIA THICKNESS Medicine & Science in Sports & Exercise. 33: S90. DOI: 10.1097/00005768-200105001-00520 |
0.508 |
|
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