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Benjamin W. Darbro, Ph.D. - Publications

Affiliations: 
2007 University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Cell Biology
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wyatt BH, Raymond TO, Lansdon LA, Darbro BW, Murray JC, Manak JR, Dickinson AJG. Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. Genesis (New York, N.Y. : 2000). e23394. PMID 32918369 DOI: 10.1002/Dvg.23394  0.349
2020 Abdelfattah F, Kariminejad A, Kahlert AK, Morrison PJ, Gumus E, Mathews KD, Darbro BW, Amor DJ, Walsh M, Sznajer Y, Weiß L, Weidensee S, Chitayat D, Shannon P, Bermejo-Sánchez E, et al. Expanding the genotypic and phenotypic spectrum of severe serine biosynthesis disorders. Human Mutation. PMID 32579715 DOI: 10.1002/Humu.24067  0.328
2020 Hildebrand JM, Kauppi M, Majewski IJ, Liu Z, Cox AJ, Miyake S, Petrie EJ, Silk MA, Li Z, Tanzer MC, Brumatti G, Young SN, Hall C, Garnish SE, Corbin J, ... ... Darbro BW, et al. A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature Communications. 11: 3150. PMID 32561755 DOI: 10.1038/S41467-020-16819-Z  0.342
2020 Kohlmeyer JL, Kaemmer CA, Pulliam C, Maharjan CK, Moreno Samayoa A, Major HJ, Cornick KE, Knepper-Adrian V, Khanna R, Sieren JC, Leidinger M, Meyerholz DK, Zamba KD, Weimer J, Dodd RD, ... Darbro B, et al. RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32086342 DOI: 10.1158/1078-0432.Ccr-19-2706  0.322
2020 Scott AT, Weitz M, Breheny PJ, Ear PH, Darbro B, Brown BJ, Braun TA, Li G, Umesalma S, Kaemmer CA, Maharjan CK, Quelle DE, Bellizzi AM, Chandrasekharan C, Dillon JS, et al. Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31937620 DOI: 10.1158/1078-0432.Ccr-19-2884  0.315
2020 Chau J, Dhungana N, Kohlmeyer J, Petronek M, Quelle D, Sato M, Darbro B, Jones K, Monga V. Genome-wide methylation analysis in long-term survivors of glioblastoma (GBM). Journal of Clinical Oncology. 38: 2552-2552. DOI: 10.1200/Jco.2020.38.15_Suppl.2552  0.314
2019 Pinnaro CT, Henry T, Major HJ, Parida M, DesJardin LE, Manak JR, Darbro BW. Candidate modifier genes for immune function in 22q11.2 deletion syndrome. Molecular Genetics & Genomic Medicine. e1057. PMID 31830774 DOI: 10.1002/Mgg3.1057  0.315
2019 Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, ... ... Darbro B, et al. Coactivation of NF-κB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood. PMID 31697816 DOI: 10.1182/Blood.2019001438  0.303
2019 Boese EA, Tollefson MR, Schnieders MJ, Darbro BW, Alward WLM, Fingert JH. Novel intragenic deletion in a pedigree with aniridia, morbid obesity, and diabetes. Current Eye Research. PMID 31361967 DOI: 10.1080/02713683.2019.1649704  0.311
2019 Cox AJ, Grady F, Velez G, Mahajan VB, Ferguson PJ, Kitchen A, Darbro BW, Bassuk AG. In trans variant calling reveals enrichment for compound heterozygous variants in genes involved in neuronal development and growth. Genetics Research. 101: e8. PMID 31190668 DOI: 10.1017/S0016672319000065  0.32
2019 Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney BL, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon JS, Merrill RA, Meyerholz DK, ... ... Darbro BW, et al. RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. The Journal of Clinical Investigation. PMID 30721156 DOI: 10.1172/Jci123049  0.336
2018 Merritt NM, Fullenkamp CA, Hall SL, Qian Q, Desai C, Thomason J, Lambertz AM, Dupuy AJ, Darbro B, Tanas MR. A comprehensive evaluation of Hippo pathway silencing in sarcomas. Oncotarget. 9: 31620-31636. PMID 30167083 DOI: 10.18632/Oncotarget.25824  0.317
2018 White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, ... ... Darbro BW, et al. A porcine model of neurofibromatosis type 1 that mimics the human disease. Jci Insight. 3. PMID 29925695 DOI: 10.1172/Jci.Insight.120402  0.323
2018 Brun BN, Willer T, Darbro BW, Gonorazky HD, Naumenko S, Dowling JJ, Campbell KP, Moore SA, Mathews KD. Uniparental disomy unveils a novel recessive mutation in POMT2. Neuromuscular Disorders : Nmd. PMID 29759639 DOI: 10.1016/J.Nmd.2018.04.003  0.325
2017 Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak JR. Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans. Genetics. PMID 29162626 DOI: 10.1534/Genetics.117.300535  0.371
2017 Keck KJ, Breheny P, Braun TA, Darbro B, Li G, Dillon JS, Bellizzi AM, O'Dorisio TM, Howe JR. Changes in gene expression in small bowel neuroendocrine tumors associated with progression to metastases. Surgery. PMID 29154080 DOI: 10.1016/J.Surg.2017.07.031  0.331
2017 Meyerholz DK, Ofori-Amanfo GK, Leidinger MR, Goeken JA, Khanna R, Sieren JC, Darbro BW, Quelle DE, Weimer JM. Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155417729357. PMID 28846462 DOI: 10.1369/0022155417729357  0.341
2017 Cox AJ, Darbro BW, Laxer RM, Velez G, Bing X, Finer AL, Erives A, Mahajan VB, Bassuk AG, Ferguson PJ. Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). Plos One. 12: e0169687. PMID 28301468 DOI: 10.1371/Journal.Pone.0169687  0.325
2017 Salma SAU, Hagen J, Reilly J, Sheehy R, Tiwari N, Nteeba J, Sherman SK, O'Dorisio TM, Howe JR, Bellizzi AM, Darbro BW, Quelle DE. Abstract 1368: RABL6A, a novel critical regulator of Akt-mTOR signaling in pancreatic neuroendocrine tumor cells Cancer Research. 77: 1368-1368. DOI: 10.1158/1538-7445.Am2017-1368  0.305
2016 Lutter M, Khan MZ, Satio K, Davis KC, Kidder IJ, McDaniel L, Darbro BW, Pieper AA, Cui H. The Eating-Disorder Associated HDAC4(A778T) Mutation Alters Feeding Behaviors in Female Mice. Biological Psychiatry. PMID 27884425 DOI: 10.1016/J.Biopsych.2016.09.024  0.311
2016 Hildebrand MS, Griffin NG, Damiano JA, Cops EJ, Burgess R, Ozturk E, Jones NC, Leventer RJ, Freeman JL, Harvey AS, Sadleir LG, Scheffer IE, Major H, Darbro BW, Allen AS, et al. Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy. American Journal of Human Genetics. PMID 27453577 DOI: 10.1016/J.Ajhg.2016.05.031  0.36
2016 Darbro BW, Singh R, Zimmerman MB, Mahajan VB, Bassuk AG. Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate. Plos One. 11: e0149041. PMID 26934580 DOI: 10.1371/Journal.Pone.0149041  0.333
2015 Damiano JA, Mullen SA, Hildebrand MS, Bellows ST, Lawrence KM, Arsov T, Dibbens L, Major H, Dahl HH, Mefford HC, Darbro BW, Scheffer IE, Berkovic SF. Evaluation of multiple putative risk alleles within the 15q13.3 region for genetic generalized epilepsy. Epilepsy Research. 117: 70-3. PMID 26421493 DOI: 10.1016/J.Eplepsyres.2015.09.007  0.337
2015 Beraldi R, Chan CH, Rogers CS, Kovács AD, Meyerholz DK, Trantzas C, Lambertz AM, Darbro BW, Weber KL, White KA, Rheeden RV, Kruer MC, Dacken BA, Wang XJ, Davis BT, et al. A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease. Human Molecular Genetics. PMID 26374845 DOI: 10.1093/Hmg/Ddv356  0.329
2015 Sherman SK, Maxwell JE, Qian Q, Bellizzi AM, Braun TA, Iannettoni MD, Darbro BW, Howe JR. Esophageal cancer in a family with hamartomatous tumors and germline PTEN frameshift and SMAD7 missense mutations. Cancer Genetics. 208: 41-6. PMID 25554686 DOI: 10.1016/J.Cancergen.2014.11.002  0.373
2015 Singh R, Darbro B, Bassuk A. GE-02 * PARADOXICAL GENETIC AND EPIDEMIOLOGIC RELATIONSHIPS BETWEEN CANCER AND AUTISM Neuro-Oncology. 17: iii7-iii7. DOI: 10.1093/Neuonc/Nov061.26  0.33
2014 Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, et al. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Research. 74: 6661-70. PMID 25273089 DOI: 10.1158/0008-5472.Can-13-3742  0.595
2014 Sieren JC, Meyerholz DK, Wang XJ, Davis BT, Newell JD, Hammond E, Rohret JA, Rohret FA, Struzynski JT, Goeken JA, Naumann PW, Leidinger MR, Taghiyev A, Van Rheeden R, Hagen J, ... Darbro BW, et al. Development and translational imaging of a TP53 porcine tumorigenesis model. The Journal of Clinical Investigation. 124: 4052-66. PMID 25105366 DOI: 10.1172/Jci75447  0.361
2014 Fingert JH, Darbro BW, Qian Q, Van Rheeden R, Miller K, Riker M, Solivan-Timpe F, Roos BR, Robin AL, Mullins RF. TBK1 and flanking genes in human retina. Ophthalmic Genetics. 35: 35-40. PMID 23421332 DOI: 10.3109/13816810.2013.768674  0.324
2014 Moore CE, Darbro B, Berg DJ, Clamon GH, Askeland RW, Abu Hejleh T. ALK, MET, and HER2 in esophageal adenocarcinoma with signet ring cell morphology. Journal of Clinical Oncology. 32: 138-138. DOI: 10.1200/Jco.2014.32.3_Suppl.138  0.324
2014 Wendlandt E, Tricot GJ, Darbro B, Zhan F. Cytogenetic Analysis of Multiple Myeloma Identifies Cytogenetic Alterations Implicated in Disease Complexity and Progression Blood. 124: 3360-3360. DOI: 10.1182/Blood.V124.21.3360.3360  0.373
2014 Sieren JC, Wang X, Davis B, Newell JD, Hammond E, Rohret J, Rohret F, Struzynski J, Goeken A, Naumann P, Leidinger M, Hagen J, Rheeden RV, Darbro BW, Quelle DE, et al. Abstract LB-162: Translational imaging of tumorigenesis in aTP53porcine cancer model Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-162  0.351
2013 Paemka L, Mahajan VB, Skeie JM, Sowers LP, Ehaideb SN, Gonzalez-Alegre P, Sasaoka T, Tao H, Miyagi A, Ueno N, Takao K, Miyakawa T, Wu S, Darbro BW, Ferguson PJ, et al. PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. Plos One. 8: e80737. PMID 24312498 DOI: 10.1371/Journal.Pone.0080737  0.32
2013 Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. Plos One. 8: e80228. PMID 24282525 DOI: 10.1371/Journal.Pone.0080228  0.355
2013 Whittier KL, Boese EA, Gibson-Corley KN, Kirby PA, Darbro BW, Qian Q, Ingram WJ, Robertson T, Remke M, Taylor MD, O'Dorisio MS. G-protein coupled receptor expression patterns delineate medulloblastoma subgroups. Acta Neuropathologica Communications. 1: 66. PMID 24252460 DOI: 10.1186/2051-5960-1-66  0.326
2013 Cui H, Moore J, Ashimi SS, Mason BL, Drawbridge JN, Han S, Hing B, Matthews A, McAdams CJ, Darbro BW, Pieper AA, Waller DA, Xing C, Lutter M. Eating disorder predisposition is associated with ESRRA and HDAC4 mutations. The Journal of Clinical Investigation. 123: 4706-13. PMID 24216484 DOI: 10.1172/Jci71400  0.344
2013 Brophy PD, Alasti F, Darbro BW, Clarke J, Nishimura C, Cobb B, Smith RJ, Manak JR. Genome-wide copy number variation analysis of a Branchio-oto-renal syndrome cohort identifies a recombination hotspot and implicates new candidate genes. Human Genetics. 132: 1339-50. PMID 23851940 DOI: 10.1007/S00439-013-1338-8  0.359
2013 Sowers LP, Loo L, Wu Y, Campbell E, Ulrich JD, Wu S, Paemka L, Wassink T, Meyer K, Bing X, El-Shanti H, Usachev YM, Ueno N, Manak JR, Manak RJ, ... ... Darbro BW, et al. Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction. Molecular Psychiatry. 18: 1077-89. PMID 23711981 DOI: 10.1038/Mp.2013.71  0.306
2013 Darbro BW, Mahajan VB, Gakhar L, Skeie JM, Campbell E, Wu S, Bing X, Millen KJ, Dobyns WB, Kessler JA, Jalali A, Cremer J, Segre A, Manak JR, Aldinger KA, et al. Mutations in extracellular matrix genes NID1 and LAMC1 cause autosomal dominant Dandy-Walker malformation and occipital cephaloceles. Human Mutation. 34: 1075-9. PMID 23674478 DOI: 10.1002/Humu.22351  0.302
2006 Darbro BW, Lee KM, Nguyen NK, Domann FE, Klingelhutz AJ. Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells. Oncogene. 25: 7421-33. PMID 16767161 DOI: 10.1038/Sj.Onc.1209729  0.541
2005 Darbro BW, Schneider GB, Klingelhutz AJ. Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes. The Journal of Investigative Dermatology. 125: 499-509. PMID 16117791 DOI: 10.1111/J.0022-202X.2005.23844.X  0.582
2005 Klingelhutz AJ, Qian Q, Phillips SL, Gourronc FA, Darbro BW, Patil SR. Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells. Virology. 340: 237-44. PMID 16051300 DOI: 10.1016/J.Virol.2005.06.027  0.552
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