Rudi D'Hooge - Publications

Affiliations: 
KUL 

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Van den Broeck L, Sierksma A, Hansquine P, Thonnard D, Callaerts-Vegh Z, D'Hooge R. Comparison between touchscreen operant chambers and water maze to detect early prefrontal dysfunction in mice. Genes, Brain, and Behavior. e12695. PMID 32812350 DOI: 10.1111/Gbb.12695  0.394
2019 Lima KR, de Vargas LDS, Ramborger B, Roehrs R, Sevenster D, Izquierdo I, D'Hooge R, Mello-Carpes PB. NORADRENERGIC AND DOPAMINERGIC INVOLVEMENT IN NOVELTY MODULATION OF AVERSIVE MEMORY GENERALIZATION OF ADULT RATS. Behavioural Brain Research. 111991. PMID 31150747 DOI: 10.1016/J.Bbr.2019.111991  0.558
2019 Elens I, Dekeyster E, Moons L, D'Hooge R. Methotrexate Affects Cerebrospinal Fluid Folate and Tau Levels and Induces Late Cognitive Deficits in Mice. Neuroscience. PMID 30703509 DOI: 10.1016/J.Neuroscience.2019.01.024  0.363
2019 Thonnard D, Dreesen E, Callaerts-Vegh Z, D'Hooge R. NMDA receptor dependence of reversal learning and the flexible use of cognitively demanding search strategies in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90: 235-244. PMID 30529376 DOI: 10.1016/J.Pnpbp.2018.12.003  0.359
2018 da Silva de Vargas L, Sevenster D, Lima K, Izquierdo I, D'Hooge R, Mello-Carpes PB. NOVELTY EXPOSURE HINDERS AVERSIVE MEMORY GENERALIZATION AND DEPENDS ON HIPPOCAMPAL PROTEIN SYNTHESIS. Behavioural Brain Research. PMID 30367969 DOI: 10.1016/J.Bbr.2018.10.034  0.561
2018 Sevenster D, Visser RM, D'Hooge R. A translational perspective on neural circuits of fear extinction: current promises and challenges. Neurobiology of Learning and Memory. PMID 29981423 DOI: 10.1016/J.Nlm.2018.07.002  0.357
2018 Stroobants S, Wolf H, Callaerts-Vegh Z, Dierks T, Lübke T, D'Hooge R. Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. Frontiers in Behavioral Neuroscience. 12: 69. PMID 29706874 DOI: 10.3389/Fnbeh.2018.00069  0.393
2018 Maes E, Krypotos AM, Boddez Y, Alfei Palloni JM, D'Hooge R, De Houwer J, Beckers T. Failures to replicate blocking are surprising and informative-Reply to Soto (2018). Journal of Experimental Psychology. General. 147: 603-610. PMID 29698031 DOI: 10.1037/Xge0000413  0.718
2018 Van der Jeugd A, Parra-Damas A, Baeta-Corral R, Soto-Faguás CM, Ahmed T, LaFerla FM, Giménez-Llort L, D'Hooge R, Saura CA. Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice. Scientific Reports. 8: 6431. PMID 29691439 DOI: 10.1038/S41598-018-24741-0  0.346
2018 Shah D, Latif-Hernandez A, De Strooper B, Saito T, Saido T, Verhoye M, D'Hooge R, Van der Linden A. Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP knock-in mice. Scientific Reports. 8: 6264. PMID 29674739 DOI: 10.1038/S41598-018-24657-9  0.401
2017 Maes E, Vanderoost E, D'Hooge R, De Houwer J, Beckers T. Individual Difference Factors in the Learning and Transfer of Patterning Discriminations. Frontiers in Psychology. 8: 1262. PMID 28804468 DOI: 10.3389/Fpsyg.2017.01262  0.717
2017 Stroobants S, Damme M, der Jeugd AV, Vermaercke B, Andersson C, Fogh J, Saftig P, Blanz J, D'Hooge R. Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice. Neurobiology of Disease. PMID 28720484 DOI: 10.1016/J.Nbd.2017.07.013  0.35
2017 Beckers L, Stroobants S, Verheijden S, West B, D'Hooge R, Baes M. Specific suppression of microgliosis cannot circumvent the severe neuropathology in peroxisomal β-oxidation-deficient mice. Molecular and Cellular Neurosciences. PMID 28286294 DOI: 10.1016/J.Mcn.2017.03.004  0.358
2017 Stroobants S, Van Acker NG, Verheijen FW, Goris I, Daneels GF, Schot R, Verbeek E, Knaapen MW, De Bondt A, Göhlmann HW, Crauwels ML, Mancini GM, Andries LJ, Moechars DW, D'Hooge R. Progressive leukoencephalopathy impairs neurobehavioral development in sialin-deficient mice. Experimental Neurology. PMID 28189729 DOI: 10.1016/J.Expneurol.2017.02.009  0.338
2017 Latif-Hernandez A, Schreurs A, Ahmed T, Van Leuven F, D'Hooge R, Balschun D. Amyloid aggravates tauopathy: stronger deficits in hippocampal and prefrontal neuroplasticity and fear memory in APP.V717IxTau.P301L vs. Tau.P301L mice Frontiers in Neuroscience. 11. DOI: 10.3389/Conf.Fnins.2017.94.00043  0.359
2017 Stroobants S, Wolf H, Callaerts-Vegh Z, Dierks T, Lübke T, D'Hooge R. Sensorimotor disintegration and neurocognitive dysfunction reflect early manifestations of neuropathology in fucosidosis mice Frontiers in Neuroscience. 11. DOI: 10.3389/Conf.Fnins.2017.94.00017  0.338
2017 Thonnard D, Callaerts-Vegh Z, D'Hooge R. Effect of MK801 on learning and memory. Frontiers in Neuroscience. 11. DOI: 10.3389/Conf.Fnins.2017.94.00012  0.321
2016 Wolf H, Damme M, Stroobants S, D'Hooge R, Beck HC, Hermans-Borgmeyer I, Lüllmann-Rauch R, Dierks T, Lübke T. A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Disease Models & Mechanisms. PMID 27491075 DOI: 10.1242/Dmm.025122  0.311
2016 Maes E, Boddez Y, Alfei JM, Krypotos AM, D'Hooge R, De Houwer J, Beckers T. The Elusive Nature of the Blocking Effect: 15 Failures to Replicate. Journal of Experimental Psychology. General. PMID 27428670 DOI: 10.1037/Xge0000200  0.716
2015 Damme M, Stroobants S, Lüdemann M, Rothaug M, Lüllmann-Rauch R, Beck HC, Ericsson A, Andersson C, Fogh J, D'Hooge R, Saftig P, Blanz J. Chronic enzyme replacement therapy ameliorates neuropathology in alpha-mannosidosis mice. Annals of Clinical and Translational Neurology. 2: 987-1001. PMID 26817023 DOI: 10.1002/Acn3.245  0.307
2015 Maes E, De Filippo G, Inkster AB, Lea SE, De Houwer J, D'Hooge R, Beckers T, Wills AJ. Feature- versus rule-based generalization in rats, pigeons and humans. Animal Cognition. PMID 26188712 DOI: 10.1007/S10071-015-0895-8  0.704
2015 Pooters T, Van der Jeugd A, Callaerts-Vegh Z, D'Hooge R. Telencephalic neurocircuitry and synaptic plasticity in rodent spatial learning and memory. Brain Research. PMID 25619550 DOI: 10.1016/J.Brainres.2015.01.015  0.353
2015 Bollen B, Ramanantsoa N, Naert A, Matrot B, Van den Bergh O, D'Hooge R, Gallego J. Emotional disorders in adult mice heterozygous for the transcription factor Phox2b. Physiology & Behavior. 141: 120-6. PMID 25582512 DOI: 10.1016/J.Physbeh.2015.01.012  0.353
2015 Dionísio PA, Amaral JD, Ribeiro MF, Lo AC, D'Hooge R, Rodrigues CM. Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset. Neurobiology of Aging. 36: 228-40. PMID 25443293 DOI: 10.1016/J.Neurobiolaging.2014.08.034  0.33
2015 Ahmed T, Blum D, Burnouf S, Demeyer D, Buée-Scherrer V, D'Hooge R, Buée L, Balschun D. Rescue of impaired late-phase long-term depression in a tau transgenic mouse model. Neurobiology of Aging. 36: 730-9. PMID 25443285 DOI: 10.1016/J.Neurobiolaging.2014.09.015  0.369
2015 Woolley DG, Mantini D, Coxon JP, D'Hooge R, Swinnen SP, Wenderoth N. Virtual water maze learning in human increases functional connectivity between posterior hippocampus and dorsal caudate. Human Brain Mapping. 36: 1265-77. PMID 25418860 DOI: 10.1002/Hbm.22700  0.341
2015 Trovò L, Stroobants S, D'Hooge R, Ledesma MD, Dotti CG. Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS. Neurobiology of Disease. 73: 319-26. PMID 25251606 DOI: 10.1016/J.Nbd.2014.09.008  0.322
2014 Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, et al. A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. Molecular Psychiatry. PMID 25450226 DOI: 10.1038/Mp.2014.151  0.376
2014 Ahmed T, Van der Jeugd A, Blum D, Galas MC, D'Hooge R, Buee L, Balschun D. Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion. Neurobiology of Aging. 35: 2474-8. PMID 24913895 DOI: 10.1016/J.Neurobiolaging.2014.05.005  0.395
2013 Piccart E, Langlois X, Vanhoof G, D'Hooge R. Selective inhibition of phosphodiesterase 10A impairs appetitive and aversive conditioning and incentive salience attribution. Neuropharmacology. 75: 437-44. PMID 23973318 DOI: 10.1016/J.Neuropharm.2013.08.006  0.326
2013 Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D'Hooge R, Stroobants S, Ahmed T, Balschun D, Willem M, Lammich S, Isbrandt D, Schweizer M, Horré K, De Strooper B, et al. Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12915-28, 12928a. PMID 23926248 DOI: 10.1523/Jneurosci.5910-12.2013  0.394
2013 Iscru E, Goddyn H, Ahmed T, Callaerts-Vegh Z, D'Hooge R, Balschun D. Improved spatial learning is associated with increased hippocampal but not prefrontal long-term potentiation in mGluR4 knockout mice. Genes, Brain, and Behavior. 12: 615-25. PMID 23714430 DOI: 10.1111/Gbb.12052  0.367
2013 Trovò L, Ahmed T, Callaerts-Vegh Z, Buzzi A, Bagni C, Chuah M, Vandendriessche T, D'Hooge R, Balschun D, Dotti CG. Low hippocampal PI(4,5)Pâ‚‚ contributes to reduced cognition in old mice as a result of loss of MARCKS. Nature Neuroscience. 16: 449-55. PMID 23434911 DOI: 10.1038/Nn.3342  0.349
2013 Callaerts-Vegh Z, Moechars D, Van Acker N, Daneels G, Goris I, Leo S, Naert A, Meert T, Balschun D, D'Hooge R. Haploinsufficiency of VGluT1 but not VGluT2 impairs extinction of spatial preference and response suppression. Behavioural Brain Research. 245: 13-21. PMID 23396167 DOI: 10.1016/j.bbr.2013.01.042  0.311
2013 Woolley DG, Laeremans A, Gantois I, Mantini D, Vermaercke B, Op de Beeck HP, Swinnen SP, Wenderoth N, Arckens L, D'Hooge R. Homologous involvement of striatum and prefrontal cortex in rodent and human water maze learning. Proceedings of the National Academy of Sciences of the United States of America. 110: 3131-6. PMID 23382228 DOI: 10.1073/Pnas.1217832110  0.36
2013 Van der Jeugd A, Blum D, Raison S, Eddarkaoui S, Buée L, D'Hooge R. Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia. Behavioural Brain Research. 242: 34-9. PMID 23247080 DOI: 10.1016/J.Bbr.2012.12.008  0.392
2013 Nuytens K, Gantois I, Stijnen P, Iscru E, Laeremans A, Serneels L, Van Eylen L, Liebhaber SA, Devriendt K, Balschun D, Arckens L, Creemers JW, D'Hooge R. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of Disease. 51: 144-51. PMID 23153818 DOI: 10.1016/J.Nbd.2012.11.004  0.389
2013 Iscru E, Ahmed T, Coremans V, Bozzi Y, Caleo M, Conway EM, D'Hooge R, Balschun D. Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region. Neuroscience. 231: 413-9. PMID 23123921 DOI: 10.1016/J.Neuroscience.2012.10.049  0.335
2012 Callaerts-Vegh Z, Leo S, Vermaercke B, Meert T, D'Hooge R. LPA5 receptor plays a role in pain sensitivity, emotional exploration and reversal learning. Genes, Brain, and Behavior. 11: 1009-19. PMID 23039190 DOI: 10.1111/J.1601-183X.2012.00840.X  0.388
2012 Boddez Y, Callaerts-Vegh Z, Vervliet B, Baeyens F, D'Hooge R, Hermans D, Beckers T. Stimulus generalization and return of fear in C57BL/6J mice. Frontiers in Behavioral Neuroscience. 6: 41. PMID 22811661 DOI: 10.3389/Fnbeh.2012.00041  0.569
2012 Matthes F, Stroobants S, Gerlach D, Wohlenberg C, Wessig C, Fogh J, Gieselmann V, Eckhardt M, D'Hooge R, Matzner U. Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age. Human Molecular Genetics. 21: 2599-609. PMID 22388935 DOI: 10.1093/Hmg/Dds086  0.329
2011 Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model. Journal of Molecular Neuroscience : Mn. 45: 432-7. PMID 21822709 DOI: 10.1007/S12031-011-9604-5  0.354
2011 Naert A, Callaerts-Vegh Z, Moechars D, Meert T, D'Hooge R. Vglut2 haploinsufficiency enhances behavioral sensitivity to MK-801 and amphetamine in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1316-21. PMID 21514350 DOI: 10.1016/J.Pnpbp.2011.03.023  0.336
2011 Ahmed T, Sabanov V, D'Hooge R, Balschun D. An N-methyl-D-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias. Neuroscience. 185: 27-38. PMID 21504782 DOI: 10.1016/J.Neuroscience.2011.04.006  0.302
2011 Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2511-25. PMID 21325519 DOI: 10.1523/Jneurosci.5245-10.2011  0.382
2011 Van der Jeugd A, Ahmed T, Burnouf S, Belarbi K, Hamdame M, Grosjean ME, Humez S, Balschun D, Blum D, Buée L, D'Hooge R. Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiology of Learning and Memory. 95: 296-304. PMID 21167950 DOI: 10.1016/J.Nlm.2010.12.005  0.418
2011 Damme M, Stroobants S, Walkley SU, Lüllmann-Rauch R, D'Hooge R, Fogh J, Saftig P, Lübke T, Blanz J. Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis. Journal of Neuropathology and Experimental Neurology. 70: 83-94. PMID 21157375 DOI: 10.1097/Nen.0B013E31820428Fa  0.313
2011 Piccart E, Gantois I, Laeremans A, de Hoogt R, Meert T, Vanhoof G, Arckens L, D'Hooge R. Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution. Neurobiology of Learning and Memory. 95: 260-9. PMID 21130175 DOI: 10.1016/j.nlm.2010.11.018  0.302
2011 Nunes A, Fonseca M, Viana R, Lo A, Strooper BD, D'Hooge R, Rodrigues C. Tudca, a bile acid, attenuates amyloid beta deposition and rescues memory deficits in app/ps1 mice Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1359  0.317
2011 Kerkhof I, Vansteenwegen D, Beckers T, Dirikx T, Baeyens F, D'Hooge R, Hermans D. The role of negative affective valence in return of fear Psychology of Fear: New Research. 153-170.  0.431
2010 Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, Hüve J, Kratzke M, Baltes J, Boening D, Böning D, Klingauf J, Schu P. AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. The Embo Journal. 29: 1318-30. PMID 20203623 DOI: 10.1038/Emboj.2010.15  0.351
2010 Coremans V, Ahmed T, Balschun D, D'Hooge R, DeVriese A, Cremer J, Antonucci F, Moons M, Baekelandt V, Reumers V, Cremer H, Eisch A, Lagace D, Janssens T, Bozzi Y, et al. Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin. Bmc Neuroscience. 11: 2. PMID 20051123 DOI: 10.1186/1471-2202-11-2  0.345
2010 Balschun D, Moechars D, Callaerts-Vegh Z, Vermaercke B, Van Acker N, Andries L, D'Hooge R. Vesicular glutamate transporter VGLUT1 has a role in hippocampal long-term potentiation and spatial reversal learning. Cerebral Cortex (New York, N.Y. : 1991). 20: 684-93. PMID 19574394 DOI: 10.1093/Cercor/Bhp133  0.381
2010 Sydow A, Jeugd AVd, Ahmed T, Balschun D, Zheng F, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Tau-induced defects in hippocampal neuroplasticity, learning and memory are reversible in a regulatable transgenic mouse model Alzheimers & Dementia. 6: 147-148. DOI: 10.1016/J.Jalz.2010.05.489  0.372
2009 Kalus I, Salmen B, Viebahn C, von Figura K, Schmitz D, D'Hooge R, Dierks T. Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity. Journal of Cellular and Molecular Medicine. 13: 4505-21. PMID 20394677 DOI: 10.1111/J.1582-4934.2008.00558.X  0.383
2009 Matzner U, Lüllmann-Rauch R, Stroobants S, Andersson C, Weigelt C, Eistrup C, Fogh J, D'Hooge R, Gieselmann V. Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 600-6. PMID 19174759 DOI: 10.1038/Mt.2008.305  0.307
2009 Van der Jeugd A, Goddyn H, Laeremans A, Arckens L, D'Hooge R, Verguts T. Hippocampal involvement in the acquisition of relational associations, but not in the expression of a transitive inference task in mice. Behavioral Neuroscience. 123: 109-14. PMID 19170435 DOI: 10.1037/A0013990  0.31
2008 Denayer E, Ahmed T, Brems H, Van Woerden G, Borgesius NZ, Callaerts-Vegh Z, Yoshimura A, Hartmann D, Elgersma Y, D'Hooge R, Legius E, Balschun D. Spred1 is required for synaptic plasticity and hippocampus-dependent learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14443-9. PMID 19118178 DOI: 10.1523/Jneurosci.4698-08.2008  0.378
2008 Martins IC, Kuperstein I, Wilkinson H, Maes E, Vanbrabant M, Jonckheere W, Van Gelder P, Hartmann D, D'Hooge R, De Strooper B, Schymkowitz J, Rousseau F. Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. The Embo Journal. 27: 224-33. PMID 18059472 DOI: 10.1038/Sj.Emboj.7601953  0.58
2008 Kuperstein I, Martins I, Wilkinson H, Vanbrabant M, Maes E, D'Hooge R, Schymkowitz J, Rousseau F, Strooper BD. O2-02-04: Lipids revert inert amyloid fibrils to neurotoxic protofibrils that affect learning in mice Alzheimers & Dementia. 4: 134-134. DOI: 10.1016/J.Jalz.2008.05.316  0.35
2007 Dirikx T, Beckers T, Muyls C, Eelen P, Vansteenwegen D, Hermans D, D'Hooge R. Differential acquisition, extinction, and reinstatement of conditioned suppression in mice. Quarterly Journal of Experimental Psychology (2006). 60: 1313-20. PMID 17853239 DOI: 10.1080/17470210701515785  0.532
2006 Moechars D, Weston MC, Leo S, Callaerts-Vegh Z, Goris I, Daneels G, Buist A, Cik M, van der Spek P, Kass S, Meert T, D'Hooge R, Rosenmund C, Hampson RM. Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12055-66. PMID 17108179 DOI: 10.1523/Jneurosci.2556-06.2006  0.336
2006 Franken S, Wittke D, Mansson JE, D'Hooge R, De Deyn PP, Lüllmann-Rauch R, Matzner U, Gieselmann V. Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase gene. Lipids in Health and Disease. 5: 21. PMID 16893448 DOI: 10.1186/1476-511X-5-21  0.352
2006 Cromphout K, Vleugels W, Heykants L, Schollen E, Keldermans L, Sciot R, D'Hooge R, De Deyn PP, von Figura K, Hartmann D, Körner C, Matthijs G. The normal phenotype of Pmm1-deficient mice suggests that Pmm1 is not essential for normal mouse development. Molecular and Cellular Biology. 26: 5621-35. PMID 16847318 DOI: 10.1128/Mcb.02357-05  0.348
2006 Callaerts-Vegh Z, Beckers T, Ball SM, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R. Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6573-82. PMID 16775145 DOI: 10.1523/Jneurosci.1497-06.2006  0.594
2006 Caeyenberghs K, Balschun D, Roces DP, Schwake M, Saftig P, D'Hooge R. Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment. Neurobiology of Disease. 23: 422-32. PMID 16766199 DOI: 10.1016/J.Nbd.2006.03.009  0.398
2006 Dirikx T, Gillard E, Muyls C, Beckers T, Hermans D, Vansteenwegen D, D'Hooge R. Reinstatement of conditioned suppression in mice Psychologica Belgica. 46: 185-195. DOI: 10.5334/Pb-46-1-2-185  0.582
2005 D'Hooge R, Lüllmann-Rauch R, Beckers T, Balschun D, Schwake M, Reiss K, von Figura K, Saftig P. Neurocognitive and psychotiform behavioral alterations and enhanced hippocampal long-term potentiation in transgenic mice displaying neuropathological features of human alpha-mannosidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6539-49. PMID 16014715 DOI: 10.1523/Jneurosci.0283-05.2005  0.581
2005 Dominguez D, Tournoy J, Hartmann D, Huth T, Cryns K, Deforce S, Serneels L, Camacho IE, Marjaux E, Craessaerts K, Roebroek AJ, Schwake M, D'Hooge R, Bach P, Kalinke U, et al. Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. The Journal of Biological Chemistry. 280: 30797-806. PMID 15987683 DOI: 10.1074/Jbc.M505249200  0.372
2005 Torremans A, Marescau B, Possemiers I, Van Dam D, D'Hooge R, Isbrandt D, De Deyn PP. Biochemical and behavioural phenotyping of a mouse model for GAMT deficiency. Journal of the Neurological Sciences. 231: 49-55. PMID 15792821 DOI: 10.1016/J.Jns.2004.12.014  0.331
2005 Torremans A, Marescau B, Van Dam D, Van Ginneken C, Van Meir F, Van Bogaert PP, D'Hooge R, de Vente J, De Deyn PP. GSA: behavioral, histological, electrophysiological and neurochemical effects. Physiology & Behavior. 84: 251-64. PMID 15708777 DOI: 10.1016/J.Physbeh.2004.12.001  0.333
2003 Frints SG, Marynen P, Hartmann D, Fryns JP, Steyaert J, Schachner M, Rolf B, Craessaerts K, Snellinx A, Hollanders K, D'Hooge R, De Deyn PP, Froyen G. CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior. Human Molecular Genetics. 12: 1463-74. PMID 12812975 DOI: 10.1093/Hmg/Ddg165  0.354
2003 Gamp AC, Tanaka Y, Lüllmann-Rauch R, Wittke D, D'Hooge R, De Deyn PP, Moser T, Maier H, Hartmann D, Reiss K, Illert AL, von Figura K, Saftig P. LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice. Human Molecular Genetics. 12: 631-46. PMID 12620969 DOI: 10.1093/Hmg/Ddg062  0.342
2003 Van Dam D, D'Hooge R, Staufenbiel M, Van Ginneken C, Van Meir F, De Deyn PP. Age-dependent cognitive decline in the APP23 model precedes amyloid deposition. The European Journal of Neuroscience. 17: 388-96. PMID 12542676 DOI: 10.1046/J.1460-9568.2003.02444.X  0.395
2001 Gantois I, Bakker CE, Reyniers E, Willemsen R, D'Hooge R, De Deyn PP, Oostra BA, Kooy RF. Restoring the phenotype of fragile X syndrome: insight from the mouse model. Current Molecular Medicine. 1: 447-55. PMID 11899089 DOI: 10.2174/1566524013363492  0.337
2001 Al Banchaabouchi M, Marescau B, D'Hooge R, De Deyn PP. The effect of high protein diet on urea and guanidino compound levels in renal insufficient mice. Amino Acids. 21: 401-15. PMID 11858699 DOI: 10.1007/S007260170005  0.312
2001 Al Banchaabouchi M, Marescau B, Van Marck E, D'hooge R, De Deyn PP. Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice. Metabolism: Clinical and Experimental. 50: 1418-25. PMID 11735086 DOI: 10.1053/Meta.2001.26763  0.339
2001 Al Banchaabouchi M, Marescau B, D'Hooge R, Van Marck E, De Deyn PP. Biochemical, histological and behavioral consequences of nephrectomy in young and aged mice. Nephron. 89: 90-100. PMID 11528238 DOI: 10.1159/000046049  0.327
2001 Matzner U, Schestag F, Hartmann D, Lüllmann-Rauch R, D'Hooge R, De Deyn PP, Gieselmann V. Bone marrow stem cell gene therapy of arylsulfatase A-deficient mice, using an arylsulfatase A mutant that is hypersecreted from retrovirally transduced donor-type cells. Human Gene Therapy. 12: 1021-33. PMID 11399225 DOI: 10.1089/104303401750214258  0.315
2001 Van Dam D, D'Hooge R, Hauben E, Reyniers E, Gantois I, Bakker CE, Oostra BA, Kooy RF, De Deyn PP. Corrigendum to “Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice” Behavioural Brain Research. 126: 219. DOI: 10.1016/S0166-4328(01)00252-2  0.316
2000 Van Dam D, D'Hooge R, Hauben E, Reyniers E, Gantois I, Bakker CE, Oostra BA, Kooy RF, De Deyn PP. Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice. Behavioural Brain Research. 117: 127-36. PMID 11099766 DOI: 10.1016/S0166-4328(00)00296-5  0.413
2000 D'Hooge R, Marescau B, Qureshi IA, De Deyn PP. Impaired cognitive performance in ornithine transcarbamylase-deficient mice on arginine-free diet. Brain Research. 876: 1-9. PMID 10973586 DOI: 10.1016/S0006-8993(00)02589-0  0.354
2000 Al Banchaabouchi M, Marescau B, D'Hooge R, Engelborghs S, De Deyn PP. Consequences of renal mass reduction on amino acid and biogenic amine levels in nephrectomized mice. Amino Acids. 18: 265-77. PMID 10901623 DOI: 10.1007/S007260050023  0.323
1999 Al Banchaabouchi M, D'Hooge R, Marescau B, De Deyn PP. Behavioural deficits during the acute phase of mild renal failure in mice. Metabolic Brain Disease. 14: 173-87. PMID 10646693 DOI: 10.1023/A:1020662725476  0.345
1999 D'hooge R, Franck F, Mucke L, De Deyn PP. Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120. The European Journal of Neuroscience. 11: 4398-402. PMID 10594667 DOI: 10.1046/J.1460-9568.1999.00857.X  0.343
1999 D'Hooge R, Coenen R, Gieselmann V, Lüllmann-Rauch R, De Deyn PP. Decline in brainstem auditory-evoked potentials coincides with loss of spiral ganglion cells in arylsulfatase A-deficient mice. Brain Research. 847: 352-6. PMID 10575108 DOI: 10.1016/S0006-8993(99)02085-5  0.353
1999 D'Hooge R, Hartmann D, Manil J, Colin F, Gieselmann V, De Deyn PP. Neuromotor alterations and cerebellar deficits in aged arylsulfatase A-deficient transgenic mice. Neuroscience Letters. 273: 93-6. PMID 10505624 DOI: 10.1016/S0304-3940(99)00647-3  0.35
1998 Gieselmann V, Matzner U, Hess B, Lüllmann-Rauch R, Coenen R, Hartmann D, D'Hooge R, DeDeyn P, Nagels G. Metachromatic leukodystrophy: molecular genetics and an animal model. Journal of Inherited Metabolic Disease. 21: 564-74. PMID 9728336 DOI: 10.1023/A:1005471106088  0.333
1998 Fransen E, D'Hooge R, Van Camp G, Verhoye M, Sijbers J, Reyniers E, Soriano P, Kamiguchi H, Willemsen R, Koekkoek SK, De Zeeuw CI, De Deyn PP, Van der Linden A, Lemmon V, Kooy RF, et al. L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns. Human Molecular Genetics. 7: 999-1009. PMID 9580664 DOI: 10.1093/Hmg/7.6.999  0.348
1997 D'Hooge R, Nagels G, Franck F, Bakker CE, Reyniers E, Storm K, Kooy RF, Oostra BA, Willems PJ, De Deyn PP. Mildly impaired water maze performance in male Fmr1 knockout mice. Neuroscience. 76: 367-76. PMID 9015322 DOI: 10.1016/S0306-4522(96)00224-2  0.381
1996 Godfraind JM, Reyniers E, De Boulle K, D'Hooge R, De Deyn PP, Bakker CE, Oostra BA, Kooy RF, Willems PJ. Long-term potentiation in the hippocampus of fragile X knockout mice. American Journal of Medical Genetics. 64: 246-51. PMID 8844057 DOI: 10.1002/(Sici)1096-8628(19960809)64:2<246::Aid-Ajmg2>3.0.Co;2-S  0.369
1996 Kooy RF, D'Hooge R, Reyniers E, Bakker CE, Nagels G, De Boulle K, Storm K, Clincke G, De Deyn PP, Oostra BA, Willems PJ. Transgenic mouse model for the fragile X syndrome. American Journal of Medical Genetics. 64: 241-5. PMID 8844056 DOI: 10.1002/(Sici)1096-8628(19960809)64:2<241::Aid-Ajmg1>3.0.Co;2-X  0.317
1995 Soetens E, Casaer S, D'Hooge R, Hueting JE. Effect of amphetamine on long-term retention of verbal material. Psychopharmacology. 119: 155-62. PMID 7659762 DOI: 10.1007/Bf02246156  0.34
1994 The Dutch-Belgian Fragile X Consorthium, Bakker CE, Verheij C, Willemsen R, van der Helm R, Oerlemans F, Vermey M, Bygrave A, Hoogeveen A, Oostra BA, Reyniers E, De Boule K, D'Hooge R, Cras P, van Velzen D, et al. Fmr1 knockout mice: A model to study fragile X mental retardation Cell. 78: 23-33. PMID 8033209 DOI: 10.1016/0092-8674(94)90569-X  0.344
1993 Soetens E, D'Hooge R, Hueting JE. Amphetamine enhances human-memory consolidation. Neuroscience Letters. 161: 9-12. PMID 8255556 DOI: 10.1016/0304-3940(93)90127-7  0.355
1992 D'Hooge R, Pei YQ, Marescau B, De Deyn PP. Behavioral toxicity of guanidinosuccinic acid in adult and young mice. Toxicology Letters. 64: 773-7. PMID 1471235 DOI: 10.1016/0378-4274(92)90261-H  0.333
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