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Christopher A. Ross - Publications

Affiliations: 
Psychiatry Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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333 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cordner ZA, Khambadkone SG, Zhu S, Bai J, Forti RR, Goodman E, Tamashiro KLK, Ross CA. Ankyrin-G Heterozygous Knockout Mice Display Increased Sensitivity to Social Defeat Stress. Complex Psychiatry. 7: 71-79. PMID 35928299 DOI: 10.1159/000518819  0.424
2021 Li T, Ning B, Kong L, Dai B, He X, Thomas JM, Sawa A, Ross CA, Smith WW. A LRRK2 GTP Binding Inhibitor, 68, Reduces LPS-Induced Signaling Events and TNF-α Release in Human Lymphoblasts. Cells. 10. PMID 33672296 DOI: 10.3390/cells10020480  0.434
2020 Wang X, Wu T, Zhang J, Guo G, He X, Pei Z, Liu Z, Liu CF, Ross CA, Smith WW. Transmembrane Protein 230 Mediates a Poly(ADP-ribose) Polymerase-1-Linked Apoptosis. Frontiers in Aging Neuroscience. 12: 235. PMID 32848711 DOI: 10.3389/Fnagi.2020.00235  0.379
2020 Klinkmueller P, Kronenbuerger M, Miao X, Bang J, Ultz KE, Paez A, Zhang X, Duan W, Margolis RL, Zijl PCV, Ross CA, Hua J. Impaired response of cerebral oxygen metabolism to visual stimulation in Huntington's disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20949286. PMID 32807001 DOI: 10.1177/0271678X20949286  0.311
2020 Tabrizi SJ, Flower MD, Ross CA, Wild EJ. Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities. Nature Reviews. Neurology. PMID 32796930 DOI: 10.1038/S41582-020-0389-4  0.36
2020 Hegde RN, Chiki A, Petricca L, Martufi P, Arbez N, Mouchiroud L, Auwerx J, Landles C, Bates GP, Singh-Bains MK, Dragunow M, Curtis MA, Faull RL, Ross CA, Caricasole A, et al. TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models. The Embo Journal. e104671. PMID 32757223 DOI: 10.15252/Embj.2020104671  0.355
2020 Jiang M, Zhang X, Liu H, LeBron J, Alexandris A, Peng Q, Gu H, Yang F, Li Y, Wang R, Hou Z, Arbez N, Ren Q, Dong JL, Whela E, ... ... Ross CA, et al. Nemo-like Kinase Reduces Mutant Huntingtin Levels and Mitigates Huntington's Disease. Human Molecular Genetics. PMID 32242231 DOI: 10.1093/Hmg/Ddaa061  0.375
2020 Thomas JM, Wang X, Guo G, Li T, Dai B, Nucifora LG, Nucifora FC, Liu Z, Xue F, Liu C, Ross CA, Smith WW. GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions. Journal of Cellular Physiology. PMID 32180220 DOI: 10.1002/Jcp.29632  0.341
2019 Arbez N, He X, Huang Y, Ren M, Liang Y, Nucifora FC, Wang X, Pei Z, Tessarolo L, Smith WW, Ross CA. G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice. Human Molecular Genetics. PMID 31813996 DOI: 10.1093/Hmg/Ddz271  0.373
2019 Shani V, Safory H, Szargel R, Wang N, Cohen T, Elghani FA, Hamza H, Savyon M, Radzishevsky I, Shaulov L, Rott R, Lim KL, Ross CA, Bandopadhyay R, Zhang H, et al. Physiological and pathological roles of LRRK2 in the nuclear envelope integrity. Human Molecular Genetics. PMID 31626293 DOI: 10.1093/Hmg/Ddz245  0.688
2019 Kronenbuerger M, Hua J, Bang JYA, Ultz KE, Miao X, Zhang X, Pekar JJ, van Zijl PCM, Duan W, Margolis RL, Ross CA. Differential Changes in Functional Connectivity of Striatum-Prefrontal and Striatum-Motor Circuits in Premanifest Huntington's Disease. Neuro-Degenerative Diseases. 1-10. PMID 31412344 DOI: 10.1159/000501616  0.327
2019 Eddings CR, Arbez N, Akimov S, Geva M, Hayden MR, Ross CA. Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor. Neurobiology of Disease. PMID 31108174 DOI: 10.1016/J.Nbd.2019.05.009  0.371
2019 Nucifora LG, MacDonald ML, Lee BJ, Peters ME, Norris AL, Orsburn BC, Yang K, Gleason K, Margolis RL, Pevsner J, Tamminga CA, Sweet RA, Ross CA, Sawa A, Nucifora FC. Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia. The American Journal of Psychiatry. appiajp201918070864. PMID 31055969 DOI: 10.1176/Appi.Ajp.2019.18070864  0.489
2019 Arbez N, Roby E, Akimov S, Eddings C, Ren M, Wang X, Ross CA. Cysteamine Protects Neurons from Mutant Huntingtin Toxicity. Journal of Huntington's Disease. PMID 30856117 DOI: 10.3233/Jhd-180312  0.348
2019 Kedaigle AJ, Fraenkel E, Atwal RS, Wu M, Gusella JF, MacDonald ME, Kaye JA, Finkbeiner S, Mattis VB, Tom CM, Svendsen C, King AR, Chen Y, Stocksdale JT, Lim RG, ... ... Ross CA, et al. Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites. Human Molecular Genetics. PMID 30768179 DOI: 10.1093/Hmg/Ddy430  0.356
2019 Nucifora L, MacDonald M, Lee B, Peters M, Norris A, Orsburn BO, Gleason K, Yang K, Margolis R, Pevsner J, Tamminga C, Sweet R, Ross C, Sawa A, Nucifora F. O2.3. Increased Protein Insolubility In Brains From A Subset Of Patients With Schizophrenia Schizophrenia Bulletin. 45. DOI: 10.1093/Schbul/Sbz021.187  0.466
2019 Nucifora L, MacDonald M, Lee B, Peters M, Norris A, Orsburn B, Yang K, Gleason K, Margolis R, Pevsner J, Tamminga C, Sweet R, Ross C, Sawa A, Nucifora F. F168. Increased Protein Insolubility in Brains From a Subset of Patients With Schizophrenia Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.705  0.464
2018 Chen L, Hua J, Ross CA, Cai S, van Zijl PCM, Li X. Altered brain iron content and deposition rate in Huntington's disease as indicated by quantitative susceptibility MRI. Journal of Neuroscience Research. PMID 30489648 DOI: 10.1002/Jnr.24358  0.31
2018 Long S, Guo W, Hu S, Su F, Zeng Y, Zeng J, Tan EK, Ross CA, Pei Z. G2019S LRRK2 Increases Stress Susceptibility Through Inhibition of DAF-16 Nuclear Translocation in a 14-3-3 Associated-Manner in . Frontiers in Neuroscience. 12: 782. PMID 30464741 DOI: 10.3389/Fnins.2018.00782  0.321
2018 Tang X, Ross CA, Johnson H, Paulsen JS, Younes L, Albin RL, Ratnanather JT, Miller MI. Regional subcortical shape analysis in premanifest Huntington's disease. Human Brain Mapping. PMID 30376191 DOI: 10.1002/Hbm.24456  0.351
2018 Ayhan F, Perez BA, Shorrock HK, Zu T, Banez-Coronel M, Reid T, Furuya H, Clark HB, Troncoso JC, Ross CA, Subramony SH, Ashizawa T, Wang ET, Yachnis AT, Ranum LP. SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F. The Embo Journal. PMID 30206144 DOI: 10.15252/Embj.201899023  0.39
2018 Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987005 DOI: 10.1073/Pnas.1801772115  0.302
2018 Wu D, Faria AV, Younes L, Ross CA, Mori S, Miller MI. Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI-Application in Premanifest Huntington's Disease. Journal of Visualized Experiments : Jove. PMID 29939188 DOI: 10.3791/57256  0.342
2018 Kronenbürger M, Hua J, Xinyuan M, Unschuld P, Zijl Pv, Ross C. P35. Cortico-striatal functional connectivity in Huntington’s disease measured with high-field functional MRI: A biomarker for disease progression? Clinical Neurophysiology. 129. DOI: 10.1016/J.Clinph.2018.04.675  0.321
2018 Cordner Z, Khambadkone S, Zhu S, Goodman E, Tamashiro K, Ross C. S92. Ankyrin-G Heterozygous Knockout Mice Display Increased Sensitivity to Social Defeat Stress Biological Psychiatry. 83: S382-S383. DOI: 10.1016/J.Biopsych.2018.02.983  0.471
2017 Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, ... Ross CA, et al. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9. PMID 29212711 DOI: 10.1126/Scitranslmed.Aal2332  0.353
2017 Li Q, Li G, Wu D, Lu H, Hou Z, Ross CA, Yang Y, Zhang J, Duan W. Resting-state functional MRI reveals altered brain connectivity and its correlation with motor dysfunction in a mouse model of Huntington's disease. Scientific Reports. 7: 16742. PMID 29196686 DOI: 10.1038/S41598-017-17026-5  0.353
2017 Arbez N, Ratovitski T, Roby E, Chighladze E, Stewart J, Ren M, Wang X, Lavery DJ, Ross CA. Posttranslational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity. The Journal of Biological Chemistry. PMID 28972180 DOI: 10.1074/Jbc.M117.782300  0.363
2017 Ross CA, Kronenbuerger M, Duan W, Margolis RL. Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies. Handbook of Clinical Neurology. 144: 15-28. PMID 28947113 DOI: 10.1016/B978-0-12-801893-4.00002-X  0.409
2017 Zhu S, Cordner ZA, Xiong J, Chiu CT, Artola A, Zuo Y, Nelson AD, Kim TY, Zaika N, Woolums BM, Hess EJ, Wang X, Chuang DM, Pletnikov MM, Jenkins PM, ... ... Ross CA, et al. Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder. Proceedings of the National Academy of Sciences of the United States of America. PMID 28894008 DOI: 10.1073/Pnas.1700689114  0.541
2017 Wu D, Faria AV, Younes L, Mori S, Brown T, Johnson H, Paulsen JS, Ross CA, Miller MI. Mapping the order and pattern of brain structural MRI changes using change-point analysis in premanifest Huntington's disease. Human Brain Mapping. PMID 28657159 DOI: 10.1002/Hbm.23713  0.303
2017 Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, ... Ross CA, et al. Post-translational modifications (PTMs), identified on endogenous huntingtin, cluster within proteolytic domains between HEAT repeats. Journal of Proteome Research. PMID 28653853 DOI: 10.1021/Acs.Jproteome.6B00991  0.358
2017 Ross CA, Bang J. Potential biomarker breakthrough for Huntington's disease. The Lancet. Neurology. PMID 28601474 DOI: 10.1016/S1474-4422(17)30195-3  0.302
2017 Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, Geater C, Morozko E, Stocksdale J, Glatzer JC, Pham JT, Ahmed I, Peng Q, Wadhwa H, Pletnikova O, ... ... Ross CA, et al. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 94: 93-107.e6. PMID 28384479 DOI: 10.1016/J.Neuron.2017.03.023  0.482
2017 Gomez-Pastor R, Burchfiel ET, Neef DW, Jaeger AM, Cabiscol E, McKinstry SU, Doss A, Aballay A, Lo DC, Akimov SS, Ross CA, Eroglu C, Thiele DJ. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nature Communications. 8: 14405. PMID 28194040 DOI: 10.1038/Ncomms14405  0.427
2017 Cordner Z, Zhu S, Tamashiro K, Ross C. Conditional Knockout of Ankyrin-G In The Mouse Forebrain Results In Bipolar-Like Behavior European Neuropsychopharmacology. 27: S485. DOI: 10.1016/J.Euroneuro.2016.09.574  0.509
2016 Lee BJ, Marchionni L, Andrews CE, Norris AL, Nucifora LG, Wu YC, Wright RA, Pevsner J, Ross CA, Margolis RL, Sawa A, Nucifora FC. Analysis of differential gene expression mediated by clozapine in human postmortem brains. Schizophrenia Research. PMID 28038920 DOI: 10.1016/J.Schres.2016.12.017  0.49
2016 Ross CA, Truant R. DNA repair: A unifying mechanism in neurodegeneration. Nature. PMID 28002410 DOI: 10.1038/Nature21107  0.319
2016 Nucifora LG, Wu YC, Lee BJ, Sha L, Margolis RL, Ross CA, Sawa A, Nucifora FC. A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation. Molecular Neuropsychiatry. 2: 133-144. PMID 27867938 DOI: 10.1159/000447358  0.45
2016 Li PP, Sun X, Xia G, Arbez N, Paul S, Zhu S, Peng HB, Ross CA, Koeppen AH, Margolis RL, Pulst SM, Ashizawa T, Rudnicki DD. ATXN2-AS, a gene antisense to ATXN2, is associated with SCA2 and ALS. Annals of Neurology. PMID 27531668 DOI: 10.1002/Ana.24761  0.561
2016 Ratovitski T, Chaerkady R, Kammers K, Stewart JC, Zavala A, Pletnikova O, Troncoso JC, Rudnicki DD, Margolis RL, Cole RN, Ross CA. Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains. Journal of Proteome Research. PMID 27486686 DOI: 10.1021/Acs.Jproteome.6B00448  0.382
2016 Lin L, Park JW, Ramachandran S, Zhang Y, Tseng YT, Shen S, Waldvogel HJ, Curtis MA, Faull RL, Troncoso JC, Ross CA, Davidson BL, Xing Y. Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease. Human Molecular Genetics. PMID 27378699 DOI: 10.1093/Hmg/Ddw187  0.394
2016 Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, ... ... Ross CA, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/Ncomms11792  0.743
2016 Meng X, Zhu S, Shevelkin A, Ross CA, Pletnikov M. DISC1, astrocytes and neuronal maturation: a possible mechanistic link with implications for mental disorders. Journal of Neurochemistry. PMID 27187935 DOI: 10.1111/Jnc.13663  0.515
2016 Faria AV, Ratnanather JT, Tward DJ, Lee DS, van den Noort F, Wu D, Brown T, Johnson H, Paulsen JS, Ross CA, Younes L, Miller MI. Linking white matter and deep gray matter alterations in premanifest Huntington disease. Neuroimage. Clinical. 11: 450-60. PMID 27104139 DOI: 10.1016/J.Nicl.2016.02.014  0.357
2016 Liu J, Li T, Thomas JM, Pei Z, Jiang H, Engelender S, Ross CA, Smith WW. Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models. Human Molecular Genetics. PMID 26744328 DOI: 10.1093/Hmg/Ddv504  0.683
2016 Ross CA, Reilmann R. E1 Diagnostic criteria for huntington’s disease based on natural history Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-314597.127  0.317
2015 Bañez-Coronel M, Ayhan F, Tarabochia AD, Zu T, Perez BA, Tusi SK, Pletnikova O, Borchelt DR, Ross CA, Margolis RL, Yachnis AT, Troncoso JC, Ranum LP. RAN Translation in Huntington Disease. Neuron. 88: 667-77. PMID 26590344 DOI: 10.1016/J.Neuron.2015.10.038  0.424
2015 Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, ... ... Ross C, et al. Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. Jama Neurology. 1-9. PMID 26569098 DOI: 10.1001/Jamaneurol.2015.2736  0.402
2015 Waldron-Roby E, Hoerauf J, Arbez N, Zhu S, Kulcsar K, Ross CA. Sox11 Reduces Caspase-6 Cleavage and Activity. Plos One. 10: e0141439. PMID 26505998 DOI: 10.1371/Journal.Pone.0141439  0.498
2015 O'Hearn EE, Hwang HS, Holmes SE, Rudnicki DD, Chung DW, Seixas AI, Cohen RL, Ross CA, Trojanowski JQ, Pletnikova O, Troncoso JC, Margolis RL. Neuropathology and Cellular Pathogenesis of Spinocerebellar Ataxia Type 12. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26340331 DOI: 10.1002/Mds.26348  0.317
2015 Sun X, Li PP, Zhu S, Cohen R, Marque LO, Ross CA, Pulst SM, Chan HY, Margolis RL, Rudnicki DD. Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65. Scientific Reports. 5: 12521. PMID 26218986 DOI: 10.1038/Srep12521  0.546
2015 Krause A, Mitchell C, Essop F, Tager S, Temlett J, Stevanin G, Ross C, Rudnicki D, Margolis R. Junctophilin 3 (JPH3) expansion mutations causing Huntington disease like 2 (HDL2) are common in South African patients with African ancestry and a Huntington disease phenotype. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26079385 DOI: 10.1002/Ajmg.B.32332  0.353
2015 Ratovitski T, Arbez N, Stewart JC, Chighladze E, Ross CA. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD). Cell Cycle (Georgetown, Tex.). 14: 1716-29. PMID 25927346 DOI: 10.1080/15384101.2015.1033595  0.419
2015 Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, et al. HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Human Molecular Genetics. 24: 3257-71. PMID 25740845 DOI: 10.1093/Hmg/Ddv080  0.361
2015 Jin J, Peng Q, Hou Z, Jiang M, Wang X, Langseth AJ, Tao M, Barker PB, Mori S, Bergles DE, Ross CA, Detloff PJ, Zhang J, Duan W. Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Human Molecular Genetics. 24: 2508-27. PMID 25609071 DOI: 10.1093/Hmg/Ddv016  0.359
2014 Paulsen JS, Long JD, Ross CA, Harrington DL, Erwin CJ, Williams JK, Westervelt HJ, Johnson HJ, Aylward EH, Zhang Y, Bockholt HJ, Barker RA. Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study. The Lancet. Neurology. 13: 1193-201. PMID 25453459 DOI: 10.1016/S1474-4422(14)70238-8  0.308
2014 Reilmann R, Leavitt BR, Ross CA. Diagnostic criteria for Huntington's disease based on natural history. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1335-41. PMID 25164527 DOI: 10.1002/Mds.26011  0.341
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Ross CA, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/Nature13716  0.35
2014 Wang R, Ross CA, Cai H, Cong WN, Daimon CM, Carlson OD, Egan JM, Siddiqui S, Maudsley S, Martin B. Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients. Frontiers in Physiology. 5: 231. PMID 25002850 DOI: 10.3389/Fphys.2014.00231  0.314
2014 Ross CA, Akimov SS. Human-induced pluripotent stem cells: potential for neurodegenerative diseases. Human Molecular Genetics. 23: R17-26. PMID 24824217 DOI: 10.1093/Hmg/Ddu204  0.367
2014 Paulsen JS, Long JD, Johnson HJ, Aylward EH, Ross CA, Williams JK, Nance MA, Erwin CJ, Westervelt HJ, Harrington DL, Bockholt HJ, Zhang Y, McCusker EA, Chiu EM, Panegyres PK, et al. Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study. Frontiers in Aging Neuroscience. 6: 78. PMID 24795630 DOI: 10.3389/Fnagi.2014.00078  0.32
2014 Ross CA, Aylward EH, Wild EJ, Langbehn DR, Long JD, Warner JH, Scahill RI, Leavitt BR, Stout JC, Paulsen JS, Reilmann R, Unschuld PG, Wexler A, Margolis RL, Tabrizi SJ. Huntington disease: natural history, biomarkers and prospects for therapeutics. Nature Reviews. Neurology. 10: 204-16. PMID 24614516 DOI: 10.1038/Nrneurol.2014.24  0.341
2014 Watkin EE, Arbez N, Waldron-Roby E, O'Meally R, Ratovitski T, Cole RN, Ross CA. Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity. Plos One. 9: e88284. PMID 24505464 DOI: 10.1371/Journal.Pone.0088284  0.321
2014 Hua J, Unschuld PG, Margolis RL, van Zijl PC, Ross CA. Elevated arteriolar cerebral blood volume in prodromal Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 396-401. PMID 23847161 DOI: 10.1002/Mds.25591  0.335
2014 Yu L, Arbez N, Nucifora LG, Sell GL, Delisi LE, Ross CA, Margolis RL, Nucifora FC. A mutation in NPAS3 segregates with mental illness in a small family. Molecular Psychiatry. 19: 7-8. PMID 23337948 DOI: 10.1038/Mp.2012.192  0.334
2014 Younes L, Ratnanather JT, Brown T, Aylward E, Nopoulos P, Johnson H, Magnotta VA, Paulsen JS, Margolis RL, Albin RL, Miller MI, Ross CA. Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis. Human Brain Mapping. 35: 792-809. PMID 23281100 DOI: 10.1002/Hbm.22214  0.337
2014 Noort Fvd, Faria A, Ratnanather T, Ross C, Mori S, Younes L, Miller M. Anatomical connectivity in prodromal Huntington Disease F1000research. 5. DOI: 10.7490/F1000Research.1096125.1  0.325
2014 Nucifora F, Nucifora L, Arbez N, Roby E, Yu L, Wei D, DeLisi L, Sawa A, Ross C, Margolis R. Poster #T175 NPAS3: NEW GENETIC AND BIOLOGICAL FINDINGS WITH IMPLICATIONS FOR PROTEIN AGGREGATION AND SCHIZOPHRENIA Schizophrenia Research. 153: S351. DOI: 10.1016/S0920-9964(14)70991-0  0.461
2013 Aylward EH, Harrington DL, Mills JA, Nopoulos PC, Ross CA, Long JD, Liu D, Westervelt HK, Paulsen JS. Regional atrophy associated with cognitive and motor function in prodromal Huntington disease. Journal of Huntington's Disease. 2: 477-89. PMID 25062732 DOI: 10.3233/Jhd-130076  0.301
2013 Unschuld PG, Liu X, Shanahan M, Margolis RL, Bassett SS, Brandt J, Schretlen DJ, Redgrave GW, Hua J, Hock C, Reading SA, van Zijl PC, Pekar JJ, Ross CA. Prefrontal executive function associated coupling relates to Huntington's disease stage. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 49: 2661-73. PMID 23906595 DOI: 10.1016/J.Cortex.2013.05.015  0.319
2013 Vashishtha M, Ng CW, Yildirim F, Gipson TA, Kratter IH, Bodai L, Song W, Lau A, Labadorf A, Vogel-Ciernia A, Troncosco J, Ross CA, Bates GP, Krainc D, Sadri-Vakili G, et al. Targeting H3K4 trimethylation in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E3027-36. PMID 23872847 DOI: 10.1073/Pnas.1311323110  0.37
2013 Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, et al. Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset. Neurogenetics. 14: 173-9. PMID 23644918 DOI: 10.1007/S10048-013-0364-Y  0.332
2013 Holley SM, Wang EA, Cepeda C, Jentsch JD, Ross CA, Pletnikov MV, Levine MS. Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia. Schizophrenia Research. 146: 264-72. PMID 23481583 DOI: 10.1016/J.Schres.2013.02.007  0.334
2013 Jiang M, Peng Q, Liu X, Jin J, Hou Z, Zhang J, Mori S, Ross CA, Ye K, Duan W. Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease. Human Molecular Genetics. 22: 2462-70. PMID 23446639 DOI: 10.1093/Hmg/Ddt098  0.397
2013 Jin J, Albertz J, Guo Z, Peng Q, Rudow G, Troncoso JC, Ross CA, Duan W. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease. Journal of Neurochemistry. 125: 410-9. PMID 23373812 DOI: 10.1111/Jnc.12190  0.415
2013 Chen H, Wang N, Zhao X, Ross CA, O'Shea KS, McInnis MG. Gene expression alterations in bipolar disorder postmortem brains. Bipolar Disorders. 15: 177-87. PMID 23360497 DOI: 10.1111/Bdi.12039  0.3
2012 Guo Z, Rudow G, Pletnikova O, Codispoti KE, Orr BA, Crain BJ, Duan W, Margolis RL, Rosenblatt A, Ross CA, Troncoso JC. Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 1379-86. PMID 22975850 DOI: 10.1002/Mds.25159  0.321
2012 Ramos EM, Latourelle JC, Lee JH, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, et al. Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset. Human Genetics. 131: 1833-40. PMID 22825315 DOI: 10.1007/S00439-012-1205-Z  0.301
2012 Lee JH, Lee JM, Ramos EM, Gillis T, Mysore JS, Kishikawa S, Hadzi T, Hendricks AE, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Gellera C, et al. TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's disease. Biochemical and Biophysical Research Communications. 424: 404-8. PMID 22771793 DOI: 10.1016/J.Bbrc.2012.06.120  0.349
2012 Yang D, Li T, Liu Z, Arbez N, Yan J, Moran TH, Ross CA, Smith WW. LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin. Neurobiology of Disease. 47: 385-92. PMID 22668778 DOI: 10.1016/J.Nbd.2012.05.020  0.331
2012 Unschuld PG, Edden RA, Carass A, Liu X, Shanahan M, Wang X, Oishi K, Brandt J, Bassett SS, Redgrave GW, Margolis RL, van Zijl PC, Barker PB, Ross CA. Brain metabolite alterations and cognitive dysfunction in early Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 895-902. PMID 22649062 DOI: 10.1002/Mds.25010  0.323
2012 Fu J, Jin J, Cichewicz RH, Hageman SA, Ellis TK, Xiang L, Peng Q, Jiang M, Arbez N, Hotaling K, Ross CA, Duan W. trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease. The Journal of Biological Chemistry. 287: 24460-72. PMID 22648412 DOI: 10.1074/Jbc.M112.382226  0.366
2012 Juopperi TA, Kim WR, Chiang CH, Yu H, Margolis RL, Ross CA, Ming GL, Song H. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells. Molecular Brain. 5: 17. PMID 22613578 DOI: 10.1186/1756-6606-5-17  0.396
2012 Ratovitski T, Chighladze E, Arbez N, Boronina T, Herbrich S, Cole RN, Ross CA. Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis. Cell Cycle (Georgetown, Tex.). 11: 2006-21. PMID 22580459 DOI: 10.4161/Cc.20423  0.365
2012 Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA. Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein. The Journal of Biological Chemistry. 287: 16017-28. PMID 22433867 DOI: 10.1074/Jbc.M111.252577  0.58
2012 Unschuld PG, Joel SE, Liu X, Shanahan M, Margolis RL, Biglan KM, Bassett SS, Schretlen DJ, Redgrave GW, van Zijl PC, Pekar JJ, Ross CA. Impaired cortico-striatal functional connectivity in prodromal Huntington's Disease. Neuroscience Letters. 514: 204-9. PMID 22425717 DOI: 10.1016/J.Neulet.2012.02.095  0.354
2012 Lee JM, Gillis T, Mysore JS, Ramos EM, Myers RH, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Griguoli A, Di Donato S, Gomez-Tortosa E, Ayuso C, et al. Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. American Journal of Human Genetics. 90: 434-44. PMID 22387017 DOI: 10.1016/J.Ajhg.2012.01.005  0.336
2012 Seixas AI, Holmes SE, Takeshima H, Pavlovich A, Sachs N, Pruitt JL, Silveira I, Ross CA, Margolis RL, Rudnicki DD. Loss of junctophilin-3 contributes to Huntington disease-like 2 pathogenesis. Annals of Neurology. 71: 245-57. PMID 22367996 DOI: 10.1002/Ana.22598  0.396
2012 Aggarwal M, Duan W, Hou Z, Rakesh N, Peng Q, Ross CA, Miller MI, Mori S, Zhang J. Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging. Neuroimage. 60: 2086-95. PMID 22342677 DOI: 10.1016/J.Neuroimage.2012.01.141  0.361
2012 Lee JM, Ramos EM, Lee JH, Gillis T, Mysore JS, Hayden MR, Warby SC, Morrison P, Nance M, Ross CA, Margolis RL, Squitieri F, Orobello S, Di Donato S, Gomez-Tortosa E, et al. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology. 78: 690-5. PMID 22323755 DOI: 10.1212/Wnl.0B013E318249F683  0.303
2012 Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA. Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 183-93. PMID 22219281 DOI: 10.1523/Jneurosci.1305-11.2012  0.369
2012 Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, ... ... Ross CA, et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nature Medicine. 18: 153-8. PMID 22179319 DOI: 10.1038/Nm.2558  0.602
2012 Rosenblatt A, Kumar BV, Mo A, Welsh CS, Margolis RL, Ross CA. Age, CAG repeat length, and clinical progression in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 272-6. PMID 22173986 DOI: 10.1002/Mds.24024  0.328
2012 Aylward EH, Liu D, Nopoulos PC, Ross CA, Pierson RK, Mills JA, Long JD, Paulsen JS. Striatal volume contributes to the prediction of onset of Huntington disease in incident cases. Biological Psychiatry. 71: 822-8. PMID 21907324 DOI: 10.1016/J.Biopsych.2011.07.030  0.309
2012 Mattis V, Svendsen S, Ebert A, Svendsen C, King A, Casale M, Winokur S, Batugedara G, Vawter M, Donovan P, Lock L, Thompson L, Zhu Y, Fossale E, Atwal R, ... ... Ross C, et al. A11 Induced pluripotent stem cells for basic and translational research on HD Journal of Neurology, Neurosurgery & Psychiatry. 83: A3.2-A4. DOI: 10.1136/Jnnp-2012-303524.11  0.395
2012 Mattis VB, Svendsen SP, Ebert A, Svendsen CN, King AR, Casale M, Winokur ST, Batugedara G, Vawter M, Donovan PJ, Lock LF, Thompson LM, Zhu Y, Fossale E, Atwal RS, ... ... Ross CA, et al. Induced pluripotent stem cells from patients with huntington’s disease show CAG repeat expansion associated phenotypes Cell Stem Cell. 11: 264-278. DOI: 10.1016/J.Stem.2012.04.027  0.377
2011 Katsel P, Tan W, Abazyan B, Davis KL, Ross C, Pletnikov MV, Haroutunian V. Expression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytes. Schizophrenia Research. 130: 238-49. PMID 21605958 DOI: 10.1016/J.Schres.2011.04.021  0.343
2011 Aylward E, Mills J, Liu D, Nopoulos P, Ross CA, Pierson R, Paulsen JS. Association between Age and Striatal Volume Stratified by CAG Repeat Length in Prodromal Huntington Disease. Plos Currents. 3: RRN1235. PMID 21593963 DOI: 10.1371/Currents.Rrn1235  0.346
2011 Wang Y, Steimle PA, Ren Y, Ross CA, Robinson DN, Egelhoff TT, Sesaki H, Iijima M. Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation Molecular Biology of the Cell. 22: 2270-2281. PMID 21562226 DOI: 10.1091/Mbc.E10-11-0926  0.313
2011 Rosenblatt A, Kumar BV, Margolis RL, Welsh CS, Ross CA. Factors contributing to institutionalization in patients with Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1711-6. PMID 21538527 DOI: 10.1002/Mds.23716  0.344
2011 Chiang CH, Su Y, Wen Z, Yoritomo N, Ross CA, Margolis RL, Song H, Ming GL. Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Molecular Psychiatry. 16: 358-60. PMID 21339753 DOI: 10.1038/Mp.2011.13  0.358
2011 Cheng Y, Peng Q, Hou Z, Aggarwal M, Zhang J, Mori S, Ross CA, Duan W. Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model. Neuroimage. 56: 1027-34. PMID 21320608 DOI: 10.1016/J.Neuroimage.2011.02.022  0.363
2011 Ratovitski T, Chighladze E, Waldron E, Hirschhorn RR, Ross CA. Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin. The Journal of Biological Chemistry. 286: 12578-89. PMID 21310951 DOI: 10.1074/Jbc.M110.185348  0.333
2011 Liu Z, Yu Y, Li X, Ross CA, Smith WW. Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism. Pharmacological Research. 63: 439-44. PMID 21237271 DOI: 10.1016/J.Phrs.2011.01.004  0.365
2011 Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA. A compact beta model of huntingtin toxicity. The Journal of Biological Chemistry. 286: 8188-96. PMID 21209075 DOI: 10.1074/Jbc.M110.192013  0.515
2011 Ross CA, Tabrizi SJ. Huntington's disease: from molecular pathogenesis to clinical treatment. The Lancet. Neurology. 10: 83-98. PMID 21163446 DOI: 10.1016/S1474-4422(10)70245-3  0.414
2011 Nopoulos PC, Aylward EH, Ross CA, Mills JA, Langbehn DR, Johnson HJ, Magnotta VA, Pierson RK, Beglinger LJ, Nance MA, Barker RA, Paulsen JS. Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment. Brain : a Journal of Neurology. 134: 137-42. PMID 20923788 DOI: 10.1093/Brain/Awq280  0.373
2011 Aylward EH, Nopoulos PC, Ross CA, Langbehn DR, Pierson RK, Mills JA, Johnson HJ, Magnotta VA, Juhl AR, Paulsen JS. Longitudinal change in regional brain volumes in prodromal Huntington disease. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 405-10. PMID 20884680 DOI: 10.1136/Jnnp.2010.208264  0.305
2011 Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV. Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. Molecular Psychiatry. 16: 293-306. PMID 20048751 DOI: 10.1038/Mp.2009.144  0.526
2010 Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, ... ... Ross CA, et al. Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biological Psychiatry. 68: 1172-81. PMID 21130225 DOI: 10.1016/J.Biopsych.2010.09.022  0.503
2010 Nopoulos PC, Aylward EH, Ross CA, Johnson HJ, Magnotta VA, Juhl AR, Pierson RK, Mills J, Langbehn DR, Paulsen JS. Cerebral cortex structure in prodromal Huntington disease. Neurobiology of Disease. 40: 544-54. PMID 20688164 DOI: 10.1016/J.Nbd.2010.07.014  0.302
2010 Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W. Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism. Journal of Neurochemistry. 114: 419-29. PMID 20412383 DOI: 10.1111/J.1471-4159.2010.06752.X  0.342
2010 Paulsen JS, Nopoulos PC, Aylward E, Ross CA, Johnson H, Magnotta VA, Juhl A, Pierson RK, Mills J, Langbehn D, Nance M. Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Research Bulletin. 82: 201-7. PMID 20385209 DOI: 10.1016/J.Brainresbull.2010.04.003  0.32
2010 Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Human Molecular Genetics. 19: 2087-98. PMID 20185556 DOI: 10.1093/Hmg/Ddq086  0.523
2010 Margolis RL, Ross CA. Neuronal signaling pathways: genetic insights into the pathophysiology of major mental illness. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 350-1. PMID 20010716 DOI: 10.1038/Npp.2009.137  0.337
2010 Li X, Liu Z, Tamashiro K, Shi B, Rudnicki DD, Ross CA, Moran TH, Smith WW. Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity. Neuroscience. 165: 455-62. PMID 19857556 DOI: 10.1016/J.Neuroscience.2009.10.042  0.391
2010 Zhang J, Peng Q, Li Q, Jahanshad N, Hou Z, Jiang M, Masuda N, Langbehn DR, Miller MI, Mori S, Ross CA, Duan W. Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage. 49: 2340-51. PMID 19850133 DOI: 10.1016/J.Neuroimage.2009.10.027  0.371
2009 Ross CA, Shoulson I. Huntington disease: pathogenesis, biomarkers, and approaches to experimental therapeutics. Parkinsonism & Related Disorders. 15: S135-8. PMID 20082975 DOI: 10.1016/S1353-8020(09)70800-4  0.393
2009 Bruce HA, Sachs N, Rudnicki DD, Lin SG, Willour VL, Cowell JK, Conroy J, McQuaid DE, Rossi M, Gaile DP, Nowak NJ, Holmes SE, Sklar P, Ross CA, Delisi LE, et al. Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations. Psychiatric Genetics. 19: 64-71. PMID 19672138 DOI: 10.1097/Ypg.0B013E3283207Ff6  0.303
2009 Liang Y, Jiang H, Ratovitski T, Jie C, Nakamura M, Hirschhorn RR, Wang X, Smith WW, Hai T, Poirier MA, Ross CA. ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line. Brain Research. 1286: 221-9. PMID 19559011 DOI: 10.1016/J.Brainres.2009.06.049  0.342
2009 Ayhan Y, Sawa A, Ross CA, Pletnikov MV. Animal models of gene-environment interactions in schizophrenia. Behavioural Brain Research. 204: 274-81. PMID 19379776 DOI: 10.1016/J.Bbr.2009.04.010  0.478
2009 Ratovitski T, Gucek M, Jiang H, Chighladze E, Waldron E, D'Ambola J, Hou Z, Liang Y, Poirier MA, Hirschhorn RR, Graham R, Hayden MR, Cole RN, Ross CA. Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells. The Journal of Biological Chemistry. 284: 10855-67. PMID 19204007 DOI: 10.1074/Jbc.M804813200  0.345
2009 Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proceedings of the National Academy of Sciences of the United States of America. 106: 2897-902. PMID 19196961 DOI: 10.1073/Pnas.0810123106  0.521
2009 Sato T, Miura M, Yamada M, Yoshida T, Wood JD, Yazawa I, Masuda M, Suzuki T, Shin RM, Yau HJ, Liu FC, Shimohata T, Onodera O, Ross CA, Katsuki M, et al. Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice. Human Molecular Genetics. 18: 723-36. PMID 19039037 DOI: 10.1093/Hmg/Ddn403  0.361
2009 Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT. Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain Human Molecular Genetics. 18: 391-404. PMID 18996920 DOI: 10.1093/Hmg/Ddn361  0.351
2009 Aylward E, Nopoulos P, Pierson R, Langbehn, Ross C, Paulsen J. Longitudinal Change in Striatal Volume in Pre-Clinical Huntington's Disease Neuroimage. 47. DOI: 10.1016/S1053-8119(09)70738-4  0.306
2009 Nopoulos P, Johnson H, Magnotta V, Pierson R, Langbehn, Ross C, Aylward E, Paulsen J. Global and Regional Brain Morphology in Subjects with Huntington's Disease Prior to Diagnosis Neuroimage. 47. DOI: 10.1016/S1053-8119(09)70715-3  0.323
2009 Pletnikov M, Ayhan Y, Abazyan B, Pardo C, Sawa A, Vogel M, Ross C. S.16.04 DISC1 mouse model of gene-environment interactions in schizophrenia European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70256-1  0.462
2008 Brandt J, Inscore AB, Ward J, Shpritz B, Rosenblatt A, Margolis RL, Ross CA. Neuropsychological deficits in Huntington's disease gene carriers and correlates of early "conversion". The Journal of Neuropsychiatry and Clinical Neurosciences. 20: 466-72. PMID 19196932 DOI: 10.1176/Jnp.2008.20.4.466  0.343
2008 Duan W, Peng Q, Masuda N, Ford E, Tryggestad E, Ladenheim B, Zhao M, Cadet JL, Wong J, Ross CA. Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease. Neurobiology of Disease. 30: 312-22. PMID 18403212 DOI: 10.1016/J.Nbd.2008.01.015  0.406
2008 Masuda N, Peng Q, Li Q, Jiang M, Liang Y, Wang X, Zhao M, Wang W, Ross CA, Duan W. Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease. Neurobiology of Disease. 30: 293-302. PMID 18395459 DOI: 10.1016/J.Nbd.2008.01.014  0.354
2008 Rudnicki DD, Pletnikova O, Vonsattel JP, Ross CA, Margolis RL. A comparison of huntington disease and huntington disease-like 2 neuropathology. Journal of Neuropathology and Experimental Neurology. 67: 366-74. PMID 18379432 DOI: 10.1097/Nen.0B013E31816B4Aee  0.416
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Ross CA, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  0.408
2008 Liu Z, Wang X, Yu Y, Li X, Wang T, Jiang H, Ren Q, Jiao Y, Sawa A, Moran T, Ross CA, Montell C, Smith WW. A Drosophila model for LRRK2-linked parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 105: 2693-8. PMID 18258746 DOI: 10.1073/Pnas.0708452105  0.538
2008 Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/Jbc.M709634200  0.318
2008 Paulsen JS, Langbehn DR, Stout JC, Aylward E, Ross CA, Nance M, Guttman M, Johnson S, MacDonald M, Beglinger LJ, Duff K, Kayson E, Biglan K, Shoulson I, Oakes D, et al. Detection of Huntington's disease decades before diagnosis: the Predict-HD study. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 874-80. PMID 18096682 DOI: 10.1136/Jnnp.2007.128728  0.328
2008 Peng Q, Masuda N, Jiang M, Li Q, Zhao M, Ross CA, Duan W. The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model. Experimental Neurology. 210: 154-63. PMID 18096160 DOI: 10.1016/J.Expneurol.2007.10.015  0.33
2008 Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA. Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Molecular Psychiatry. 13: 173-86, 115. PMID 17848917 DOI: 10.1038/Sj.Mp.4002079  0.363
2008 BIGLAN K, ROSS C, LANGBEHN D, AYLWARD E, STOUT J, QUELLER S, CARLOZZI N, DUFF K, BEGLINGER L, PAULSEN J. Subtle Motor Abnormalities in Pre-Manifest HD Are Associated With Gene Status, Probability of Disease Onset, and Striatal Atrophy Neurotherapeutics. 5: 362-362. DOI: 10.1016/J.Nurt.2007.10.054  0.34
2007 Ross CA, Smith WW. Gene-environment interactions in Parkinson's disease. Parkinsonism & Related Disorders. 13: S309-15. PMID 18267256 DOI: 10.1016/S1353-8020(08)70022-1  0.314
2007 Ratovitski T, Nakamura M, D'Ambola J, Chighladze E, Liang Y, Wang W, Graham R, Hayden MR, Borchelt DR, Hirschhorn RR, Ross CA. N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease. Cell Cycle (Georgetown, Tex.). 6: 2970-81. PMID 18156806 DOI: 10.4161/Cc.6.23.4992  0.353
2007 Williams RB, Gutekunst WR, Joyner PM, Duan W, Li Q, Ross CA, Williams TD, Cichewicz RH. Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity. Journal of Agricultural and Food Chemistry. 55: 9450-6. PMID 17944533 DOI: 10.1021/Jf072241X  0.348
2007 Colomer Gould VF, Goti D, Pearce D, Gonzalez GA, Gao H, Bermudez de Leon M, Jenkins NA, Copeland NG, Ross CA, Brown DR. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice. Neurobiology of Disease. 27: 362-9. PMID 17632007 DOI: 10.1016/J.Nbd.2007.06.005  0.354
2007 Pletnikov MV, Xu Y, Ovanesov MV, Kamiya A, Sawa A, Ross CA. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Neuroscience Research. 58: 234-44. PMID 17418909 DOI: 10.1016/J.Neures.2007.03.003  0.525
2007 Schilling G, Klevytska A, Tebbenkamp AT, Juenemann K, Cooper J, Gonzales V, Slunt H, Poirer M, Ross CA, Borchelt DR. Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models. Journal of Neuropathology and Experimental Neurology. 66: 313-20. PMID 17413322 DOI: 10.1097/Nen.0B013E318040B2C8  0.358
2007 Rudnicki DD, Holmes SE, Lin MW, Thornton CA, Ross CA, Margolis RL. Huntington's disease--like 2 is associated with CUG repeat-containing RNA foci. Annals of Neurology. 61: 272-82. PMID 17387722 DOI: 10.1002/Ana.21081  0.342
2007 Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW. Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death. Neurobiology of Aging. 28: 1709-17. PMID 16978743 DOI: 10.1016/J.Neurobiolaging.2006.07.017  0.527
2006 Ross CA, Thompson LM. Transcription meets metabolism in neurodegeneration. Nature Medicine. 12: 1239-41. PMID 17088887 DOI: 10.1038/Nm1106-1239  0.332
2006 Ross CA, Cleveland DW. Intercellular miscommunication in polyglutamine pathogenesis. Nature Neuroscience. 9: 1205-6. PMID 17001335 DOI: 10.1038/Nn1006-1205  0.345
2006 Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nature Neuroscience. 9: 1231-3. PMID 16980962 DOI: 10.1038/Nn1776  0.541
2006 Bord L, Wheeler J, Paek M, Saleh M, Lyons-Warren A, Ross CA, Sawamura N, Sawa A. Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history. Neuroscience Research. 56: 286-93. PMID 16965828 DOI: 10.1016/J.Neures.2006.07.010  0.5
2006 Holmes SE, Wentzell JS, Seixas AI, Callahan C, Silveira I, Ross CA, Margolis RL. A novel trinucleotide repeat expansion at chromosome 3q26.2 identified by a CAG/CTG repeat expansion detection array. Human Genetics. 120: 193-200. PMID 16783570 DOI: 10.1007/S00439-006-0207-0  0.336
2006 Schilling B, Gafni J, Torcassi C, Cong X, Row RH, LaFevre-Bernt MA, Cusack MP, Ratovitski T, Hirschhorn R, Ross CA, Gibson BW, Ellerby LM. Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity. The Journal of Biological Chemistry. 281: 23686-97. PMID 16782707 DOI: 10.1074/Jbc.M513507200  0.315
2006 Paulsen JS, Hayden M, Stout JC, Langbehn DR, Aylward E, Ross CA, Guttman M, Nance M, Kieburtz K, Oakes D, Shoulson I, Kayson E, Johnson S, Penziner E. Preparing for preventive clinical trials: the Predict-HD study. Archives of Neurology. 63: 883-90. PMID 16769871 DOI: 10.1001/Archneur.63.6.883  0.336
2006 Jiang H, Poirier MA, Liang Y, Pei Z, Weiskittel CE, Smith WW, DeFranco DB, Ross CA. Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin. Neurobiology of Disease. 23: 543-51. PMID 16766198 DOI: 10.1016/J.Nbd.2006.04.011  0.385
2006 Rosenblatt A, Liang KY, Zhou H, Abbott MH, Gourley LM, Margolis RL, Brandt J, Ross CA. The association of CAG repeat length with clinical progression in Huntington disease. Neurology. 66: 1016-20. PMID 16606912 DOI: 10.1212/01.Wnl.0000204230.16619.D9  0.324
2006 Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proceedings of the National Academy of Sciences of the United States of America. 103: 3405-9. PMID 16492755 DOI: 10.1073/Pnas.0511316103  0.759
2006 Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM. Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin. Neurobiology of Disease. 21: 381-91. PMID 16150600 DOI: 10.1016/J.Nbd.2005.07.014  0.546
2006 Porat Y, Hou Z, Ross C, Poirier M. Huntingtin oligomeric structures and their potential neurotoxic role in Huntington's disease Nanomedicine: Nanotechnology, Biology and Medicine. 2: 317. DOI: 10.1016/J.Nano.2006.10.153  0.322
2005 Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 18676-81. PMID 16352719 DOI: 10.1073/Pnas.0508052102  0.556
2005 Jin K, LaFevre-Bernt M, Sun Y, Chen S, Gafni J, Crippen D, Logvinova A, Ross CA, Greenberg DA, Ellerby LM. FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 18189-94. PMID 16326808 DOI: 10.1073/Pnas.0506375102  0.367
2005 Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nature Cell Biology. 7: 1167-78. PMID 16299498 DOI: 10.1038/Ncb1328  0.479
2005 West AB, Moore DJ, Biskup S, Bugayenko A, Smith WW, Ross CA, Dawson VL, Dawson TM. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 16842-7. PMID 16269541 DOI: 10.1073/Pnas.0507360102  0.53
2005 Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Human Molecular Genetics. 14: 3801-11. PMID 16239241 DOI: 10.1093/Hmg/Ddi396  0.605
2005 Reading SA, Yassa MA, Bakker A, Dziorny AC, Gourley LM, Yallapragada V, Rosenblatt A, Margolis RL, Aylward EH, Brandt J, Mori S, van Zijl P, Bassett SS, Ross CA. Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study. Psychiatry Research. 140: 55-62. PMID 16199141 DOI: 10.1016/J.Pscychresns.2005.05.011  0.332
2005 Ross CA, Poirier MA. Opinion: What is the role of protein aggregation in neurodegeneration? Nature Reviews. Molecular Cell Biology. 6: 891-8. PMID 16167052 DOI: 10.1038/Nrm1742  0.348
2005 Jenkins BG, Andreassen OA, Dedeoglu A, Leavitt B, Hayden M, Borchelt D, Ross CA, Ferrante RJ, Beal MF. Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease. Journal of Neurochemistry. 95: 553-62. PMID 16135087 DOI: 10.1111/J.1471-4159.2005.03411.X  0.349
2005 Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y, Hayward SD, Moran TH, Montell C, Ross CA, Snyder SH, Sawa A. p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease. Neuron. 47: 29-41. PMID 15996546 DOI: 10.1016/J.Neuron.2005.06.005  0.7
2005 Smith WW, Margolis RL, Li X, Troncoso JC, Lee MK, Dawson VL, Dawson TM, Iwatsubo T, Ross CA. Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5544-52. PMID 15944382 DOI: 10.1523/Jneurosci.0482-05.2005  0.482
2005 Sachs NA, Sawa A, Holmes SE, Ross CA, DeLisi LE, Margolis RL. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Molecular Psychiatry. 10: 758-64. PMID 15940305 DOI: 10.1038/Sj.Mp.4001667  0.484
2005 Wang W, Duan W, Igarashi S, Morita H, Nakamura M, Ross CA. Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model. Neurobiology of Disease. 20: 500-8. PMID 15908226 DOI: 10.1016/J.Nbd.2005.03.026  0.341
2005 Swift-Scanlan T, Coughlin JM, Lan TH, Potash JB, Ingersoll RG, Depaulo R, Ross CA, McInnis MG. Characterization of CTG/CAG repeats on chromosome 18: a study of bipolar disorder. Psychiatric Genetics. 15: 91-9. PMID 15900223 DOI: 10.1097/00041444-200506000-00005  0.319
2005 Sawa A, Nagata E, Sutcliffe S, Dulloor P, Cascio MB, Ozeki Y, Roy S, Ross CA, Snyder SH. Huntingtin is cleaved by caspases in the cytoplasm and translocated to the nucleus via perinuclear sites in Huntington's disease patient lymphoblasts. Neurobiology of Disease. 20: 267-74. PMID 15890517 DOI: 10.1016/J.Nbd.2005.02.013  0.585
2005 Lim KL, Chew KC, Tan JM, Wang C, Chung KK, Zhang Y, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2002-9. PMID 15728840 DOI: 10.1523/Jneurosci.4474-04.2005  0.707
2005 Zainelli GM, Dudek NL, Ross CA, Kim SY, Muma NA. Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3. Journal of Neuropathology and Experimental Neurology. 64: 58-65. PMID 15715085 DOI: 10.1093/Jnen/64.1.58  0.373
2005 Poirier MA, Jiang H, Ross CA. A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure. Human Molecular Genetics. 14: 765-74. PMID 15689354 DOI: 10.1093/Hmg/Ddi071  0.334
2005 Sawamura N, Sawamura-Yamamoto T, Ozeki Y, Ross CA, Sawa A. A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proceedings of the National Academy of Sciences of the United States of America. 102: 1187-92. PMID 15657124 DOI: 10.1073/Pnas.0406543102  0.489
2005 Cornett J, Cao F, Wang CE, Ross CA, Bates GP, Li SH, Li XJ. Polyglutamine expansion of huntingtin impairs its nuclear export. Nature Genetics. 37: 198-204. PMID 15654337 DOI: 10.1038/Ng1503  0.354
2005 Ross CA, Margolis RL. Neurogenetics: Insights into degenerative diseases and approaches to schizophrenia Clinical Neuroscience Research. 5: 3-14. DOI: 10.1016/J.Cnr.2005.07.001  0.394
2004 Ross CA, Pickart CM. The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases Trends in Cell Biology. 14: 703-711. PMID 15564047 DOI: 10.1016/J.Tcb.2004.10.006  0.398
2004 Goti D, Katzen SM, Mez J, Kurtis N, Kiluk J, Ben-Haïem L, Jenkins NA, Copeland NG, Kakizuka A, Sharp AH, Ross CA, Mouton PR, Colomer V. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10266-79. PMID 15537899 DOI: 10.1523/Jneurosci.2734-04.2004  0.381
2004 Margolis RL, Holmes SE, Rosenblatt A, Gourley L, O'Hearn E, Ross CA, Seltzer WK, Walker RH, Ashizawa T, Rasmussen A, Hayden M, Almqvist EW, Harris J, Fahn S, MacDonald ME, et al. Huntington's Disease-like 2 (HDL2) in North America and Japan. Annals of Neurology. 56: 670-4. PMID 15468075 DOI: 10.1002/Ana.20248  0.358
2004 Ross CA, Poirier MA. Protein aggregation and neurodegenerative disease Nature Medicine. 10: S10. PMID 15272267 DOI: 10.1038/Nm1066  0.385
2004 Ross CA. Huntington's disease: New paths to pathogenesis Cell. 118: 4-7. PMID 15242639 DOI: 10.1016/J.Cell.2004.06.022  0.361
2004 Schilling G, Savonenko AV, Klevytska A, Morton JL, Tucker SM, Poirier M, Gale A, Chan N, Gonzales V, Slunt HH, Coonfield ML, Jenkins NA, Copeland NG, Ross CA, Borchelt DR. Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice. Human Molecular Genetics. 13: 1599-610. PMID 15190011 DOI: 10.1093/Hmg/Ddh175  0.374
2004 Reading SA, Dziorny AC, Peroutka LA, Schreiber M, Gourley LM, Yallapragada V, Rosenblatt A, Margolis RL, Pekar JJ, Pearlson GD, Aylward E, Brandt J, Bassett SS, Ross CA. Functional brain changes in presymptomatic Huntington's disease. Annals of Neurology. 55: 879-83. PMID 15174024 DOI: 10.1002/Ana.20121  0.319
2004 Nagata E, Sawa A, Ross CA, Snyder SH. Autophagosome-like vacuole formation in Huntington's disease lymphoblasts. Neuroreport. 15: 1325-8. PMID 15167559 DOI: 10.1097/01.Wnr.0000127073.66692.8F  0.613
2004 Schilling G, Savonenko AV, Coonfield ML, Morton JL, Vorovich E, Gale A, Neslon C, Chan N, Eaton M, Fromholt D, Ross CA, Borchelt DR. Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice. Experimental Neurology. 187: 137-49. PMID 15081595 DOI: 10.1016/J.Expneurol.2004.01.003  0.318
2004 Liani E, Eyal A, Avraham E, Shemer R, Szargel R, Berg D, Bornemann A, Riess O, Ross CA, Rott R, Engelender S. Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 5500-5. PMID 15064394 DOI: 10.1073/Pnas.0401081101  0.681
2004 Djoussé L, Knowlton B, Hayden MR, Almqvist EW, Brinkman RR, Ross CA, Margolis RL, Rosenblatt A, Durr A, Dode C, Morrison PJ, Novelletto A, Frontali M, Trent RJ, McCusker E, et al. Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16. Neurogenetics. 5: 109-14. PMID 15029481 DOI: 10.1007/S10048-004-0175-2  0.354
2004 Zainelli GM, Ross CA, Troncoso JC, Fitzgerald JK, Muma NA. Calmodulin regulates transglutaminase 2 cross-linking of huntingtin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1954-61. PMID 14985437 DOI: 10.1523/Jneurosci.4424-03.2004  0.36
2004 Rangone H, Poizat G, Troncoso J, Ross CA, MacDonald ME, Saudou F, Humbert S. The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin. The European Journal of Neuroscience. 19: 273-9. PMID 14725621 DOI: 10.1111/J.0953-816X.2003.03131.X  0.337
2004 Tsutsumi T, Holmes SE, McInnis MG, Sawa A, Callahan C, DePaulo JR, Ross CA, DeLisi LE, Margolis RL. Novel CAG/CTG repeat expansion mutations do not contribute to the genetic risk for most cases of bipolar disorder or schizophrenia. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 15-9. PMID 14681907 DOI: 10.1002/Ajmg.B.20058  0.477
2004 Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A. Erratum: Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth (Proceedings of the National Academy of Sciences of the United States of America (January 7, 2003) 100, 1 (289-294)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0405527101  0.525
2004 Margolis RL, Holmes SE, Rosenblatt A, Gourley L, O'Hearn E, Ross CA, Seltzer WK, Walker RH, Ashizawa T, Rasmussen A, Hayden M, Almqvist EW, Harris J, Fahn S, MacDonald ME, et al. Erratum: Huntington's disease-like 2 (HDL2) in North America and Japan (Annals of Neurology (November 2004) 56 (670-674)) Annals of Neurology. 56. DOI: 10.1002/Ana.20349  0.319
2003 Rosenblatt A, Abbott MH, Gourley LM, Troncoso JC, Margolis RL, Brandt J, Ross CA. Predictors of neuropathological severity in 100 patients with Huntington's disease. Annals of Neurology. 54: 488-93. PMID 14520661 DOI: 10.1002/Ana.10691  0.322
2003 Margolis RL, Ross CA. Diagnosis of Huntington disease. Clinical Chemistry. 49: 1726-32. PMID 14500613 DOI: 10.1373/49.10.1726  0.341
2003 Li JL, Hayden MR, Almqvist EW, Brinkman RR, Durr A, Dodé C, Morrison PJ, Suchowersky O, Ross CA, Margolis RL, Rosenblatt A, Gómez-Tortosa E, Cabrero DM, Novelletto A, Frontali M, et al. A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. American Journal of Human Genetics. 73: 682-7. PMID 12900792 DOI: 10.1086/378133  0.322
2003 Marx FP, Holzmann C, Strauss KM, Li L, Eberhardt O, Gerhardt E, Cookson MR, Hernandez D, Farrer MJ, Kachergus J, Engelender S, Ross CA, Berger K, Schöls L, Schulz JB, et al. Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease. Human Molecular Genetics. 12: 1223-31. PMID 12761037 DOI: 10.1093/Hmg/Ddg134  0.683
2003 Igarashi S, Morita H, Bennett KM, Tanaka Y, Engelender S, Peters MF, Cooper JK, Wood JD, Sawa A, Ross CA. Inducible PC12 cell model of Huntington's disease shows toxicity and decreased histone acetylation. Neuroreport. 14: 565-8. PMID 12657886 DOI: 10.1097/00001756-200303240-00007  0.721
2003 Zainelli GM, Ross CA, Troncoso JC, Muma NA. Transglutaminase cross-links in intranuclear inclusions in Huntington disease. Journal of Neuropathology and Experimental Neurology. 62: 14-24. PMID 12528814 DOI: 10.1093/Jnen/62.1.14  0.36
2003 Ross CA, Poirier MA, Wanker EE, Amzel M. Polyglutamine fibrillogenesis: the pathway unfolds. Proceedings of the National Academy of Sciences of the United States of America. 100: 1-3. PMID 12509507 DOI: 10.1073/Pnas.0237018100  0.381
2003 Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, Fujii K, Okawa M, Yamada N, Hatten ME, Snyder SH, Ross CA, Sawa A. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 100: 289-94. PMID 12506198 DOI: 10.1073/Pnas.0136913100  0.595
2003 Jiang H, Nucifora FC, Ross CA, DeFranco DB. Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein. Human Molecular Genetics. 12: 1-12. PMID 12490527 DOI: 10.1093/Hmg/Ddg002  0.404
2003 Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. The Journal of Biological Chemistry. 278: 13047-55. PMID 12464607 DOI: 10.1074/Jbc.M211224200  0.626
2002 Sun B, Fan W, Balciunas A, Cooper JK, Bitan G, Steavenson S, Denis PE, Young Y, Adler B, Daugherty L, Manoukian R, Elliott G, Shen W, Talvenheimo J, Teplow DB, ... ... Ross CA, et al. Polyglutamine repeat length-dependent proteolysis of huntingtin. Neurobiology of Disease. 11: 111-22. PMID 12460551 DOI: 10.1006/Nbdi.2002.0539  0.35
2002 Ross CA. Polyglutamine pathogenesis: Emergence of unifying mechanisms for Huntington's disease and related disorders Neuron. 35: 819-822. PMID 12372277 DOI: 10.1016/S0896-6273(02)00872-3  0.389
2002 Poirier MA, Li H, Macosko J, Cai S, Amzel M, Ross CA. Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. The Journal of Biological Chemistry. 277: 41032-7. PMID 12171927 DOI: 10.1074/Jbc.M205809200  0.337
2002 Luthi-Carter R, Strand AD, Hanson SA, Kooperberg C, Schilling G, La Spada AR, Merry DE, Young AB, Ross CA, Borchelt DR, Olson JM. Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Human Molecular Genetics. 11: 1927-37. PMID 12165555 DOI: 10.1093/Hmg/11.17.1927  0.537
2002 Leroi I, O'Hearn E, Marsh L, Lyketsos CG, Rosenblatt A, Ross CA, Brandt J, Margolis RL. Psychopathology in patients with degenerative cerebellar diseases: a comparison to Huntington's disease. The American Journal of Psychiatry. 159: 1306-14. PMID 12153822 DOI: 10.1176/Appi.Ajp.159.8.1306  0.344
2002 Bauer I, Gencik M, Laccone F, Peters H, Weber BH, Feder EH, Weirich H, Morris-Rosendahl DJ, Rolfs A, Gencikova A, Bauer P, Wenning GK, Epplen JT, Holmes SE, Margolis RL, ... Ross CA, et al. Trinucleotide repeat expansions in the junctophilin-3 gene are not found in Caucasian patients with a Huntington's disease-like phenotype. Annals of Neurology. 51: 662. PMID 12112122 DOI: 10.1002/Ana.10184  0.357
2002 de Almeida LP, Ross CA, Zala D, Aebischer P, Déglon N. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3473-83. PMID 11978824 DOI: 10.1523/Jneurosci.22-09-03473.2002  0.377
2002 Chan EY, Nasir J, Gutekunst CA, Coleman S, Maclean A, Maas A, Metzler M, Gertsenstein M, Ross CA, Nagy A, Hayden MR. Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior. Human Molecular Genetics. 11: 945-59. PMID 11971876 DOI: 10.1093/Hmg/11.8.945  0.319
2002 Ribeiro CS, Carneiro K, Ross CA, Menezes JR, Engelender S. Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein. The Journal of Biological Chemistry. 277: 23927-33. PMID 11956199 DOI: 10.1074/Jbc.M201115200  0.63
2002 Stevanin G, Camuzat A, Holmes SE, Julien C, Sahloul R, Dodé C, Hahn-Barma V, Ross CA, Margolis RL, Durr A, Brice A. CAG/CTG repeat expansions at the Huntington's disease-like 2 locus are rare in Huntington's disease patients. Neurology. 58: 965-7. PMID 11914418 DOI: 10.1212/Wnl.58.6.965  0.364
2002 Wakabayashi K, Engelender S, Tanaka Y, Yoshimoto M, Mori F, Tsuji S, Ross CA, Takahashi H. Immunocytochemical localization of synphilin-1, an alpha-synuclein-associated protein, in neurodegenerative disorders. Acta Neuropathologica. 103: 209-14. PMID 11907799 DOI: 10.1007/S004010100451  0.678
2002 Holmes SE, O'Hearn E, Rosenblatt A, Callahan C, Hwang HS, Ingersoll-Ashworth RG, Fleisher A, Stevanin G, Brice A, Potter NT, Ross CA, Margolis RL. Erratum: A CTG trinucleotide repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2 (Nature Genetics (2001) 29 (377-378)) Nature Genetics. 30. DOI: 10.1038/Ng0102-123A  0.338
2001 Chen H, Ross CA, Wang N, Huo Y, MacKinnon DF, Potash JB, Simpson SG, McMahon FJ, DePaulo Jr JR, McInnis MG. NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene. European Journal of Human Genetics : Ejhg. 9: 922-30. PMID 11840194 DOI: 10.1038/Sj.Ejhg.5200747  0.329
2001 Margolis RL, O'Hearn E, Rosenblatt A, Willour V, Holmes SE, Franz ML, Callahan C, Hwang HS, Troncoso JC, Ross CA. A disorder similar to Huntington's disease is associated with a novel CAG repeat expansion. Annals of Neurology. 50: 373-80. PMID 11761463 DOI: 10.1002/Ana.1312  0.386
2001 Holmes SE, Hearn EO, Ross CA, Margolis RL. SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia. Brain Research Bulletin. 56: 397-403. PMID 11719278 DOI: 10.1016/S0361-9230(01)00596-2  0.39
2001 Schilling G, Coonfield ML, Ross CA, Borchelt DR. Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model. Neuroscience Letters. 315: 149-53. PMID 11716985 DOI: 10.1016/S0304-3940(01)02326-6  0.325
2001 Holmes SE, O'Hearn E, Rosenblatt A, Callahan C, Hwang HS, Ingersoll-Ashworth RG, Fleisher A, Stevanin G, Brice A, Potter NT, Ross CA, Margolis RL. A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease-like 2. Nature Genetics. 29: 377-8. PMID 11694876 DOI: 10.1038/Ng760  0.358
2001 Margolis RL, Ross CA. Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases. Trends in Molecular Medicine. 7: 479-82. PMID 11689312 DOI: 10.1016/S1471-4914(01)02179-7  0.394
2001 Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nature Medicine. 7: 1144-50. PMID 11590439 DOI: 10.1038/Nm1001-1144  0.526
2001 Xu J, Paquet M, Lau AG, Wood JD, Ross CA, Hall RA. beta 1-adrenergic receptor association with the synaptic scaffolding protein membrane-associated guanylate kinase inverted-2 (MAGI-2). Differential regulation of receptor internalization by MAGI-2 and PSD-95. The Journal of Biological Chemistry. 276: 41310-7. PMID 11526121 DOI: 10.1074/Jbc.M107480200  0.315
2001 Paulsen JS, Zhao H, Stout JC, Brinkman RR, Guttman M, Ross CA, Como P, Manning C, Hayden MR, Shoulson I. Clinical markers of early disease in persons near onset of Huntington's disease. Neurology. 57: 658-62. PMID 11524475 DOI: 10.1212/Wnl.57.4.658  0.349
2001 Andreassen OA, Ferrante RJ, Huang HM, Dedeoglu A, Park L, Ferrante KL, Kwon J, Borchelt DR, Ross CA, Gibson GE, Beal MF. Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease. Annals of Neurology. 50: 112-7. PMID 11456300 DOI: 10.1002/Ana.1085  0.355
2001 Andreassen OA, Dedeoglu A, Ferrante RJ, Jenkins BG, Ferrante KL, Thomas M, Friedlich A, Browne SE, Schilling G, Borchelt DR, Hersch SM, Ross CA, Beal MF. Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease. Neurobiology of Disease. 8: 479-91. PMID 11447996 DOI: 10.1006/Nbdi.2001.0406  0.349
2001 Schilling G, Jinnah HA, Gonzales V, Coonfield ML, Kim Y, Wood JD, Price DL, Li XJ, Jenkins N, Copeland N, Moran T, Ross CA, Borchelt DR. Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA. Neurobiology of Disease. 8: 405-18. PMID 11442350 DOI: 10.1006/Nbdi.2001.0385  0.388
2001 Chun W, Lesort M, Tucholski J, Faber PW, MacDonald ME, Ross CA, Johnson GV. Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells. Neurobiology of Disease. 8: 391-404. PMID 11442349 DOI: 10.1006/Nbdi.2001.0390  0.387
2001 Bandopadhyay R, de Silva R, Khan N, Graham E, Vaughan J, Engelender S, Ross C, Morris H, Morris C, Wood NW, Daniel S, Lees A. No pathogenic mutations in the synphilin-1 gene in Parkinson's disease. Neuroscience Letters. 307: 125-7. PMID 11427316 DOI: 10.1016/S0304-3940(01)01935-8  0.675
2001 Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, L Dawson V, Dawson TM, Ross CA. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Molecular Genetics. 10: 919-26. PMID 11309365 DOI: 10.1093/Hmg/10.9.919  0.758
2001 Farrer M, Destée A, Levecque C, Singleton A, Engelender S, Becquet E, Mouroux V, Richard F, Defebvre L, Crook R, Hernandez D, Ross CA, Hardy J, Amouyel P, Chartier-Harlin MC. Genetic analysis of synphilin-1 in familial Parkinson's disease. Neurobiology of Disease. 8: 317-23. PMID 11300726 DOI: 10.1006/Nbdi.2000.0326  0.677
2001 Chun W, Lesort M, Tucholski J, Ross CA, Johnson GV. Tissue transglutaminase does not contribute to the formation of mutant huntingtin aggregates. The Journal of Cell Biology. 153: 25-34. PMID 11285271 DOI: 10.1083/Jcb.153.1.25  0.356
2001 Nucifora FC, Sasaki M, Peters MF, Huang H, Cooper JK, Yamada M, Takahashi H, Tsuji S, Troncoso J, Dawson VL, Dawson TM, Ross CA. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science (New York, N.Y.). 291: 2423-8. PMID 11264541 DOI: 10.1126/Science.1056784  0.563
2001 Yamada M, Wood JD, Shimohata T, Hayashi S, Tsuji S, Ross CA, Takahashi H. Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy. Annals of Neurology. 49: 14-23. PMID 11198291 DOI: 10.1002/1531-8249(200101)49:1<14::Aid-Ana5>3.0.Co;2-X  0.346
2001 Holbert S, Denghien I, Kiechle T, Rosenblatt A, Wellington C, Hayden MR, Margolis RL, Ross CA, Dausset J, Ferrante RJ, Néri C. The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 1811-6. PMID 11172033 DOI: 10.1073/Pnas.98.4.1811  0.38
2001 Ross CA, Margolis RL. Huntington's disease Clinical Neuroscience Research. 1: 142-152. DOI: 10.1016/S1566-2772(00)00014-1  0.41
2000 Peters MF, Ross CA. Isolation of a 40-kDa Huntingtin-associated protein. The Journal of Biological Chemistry. 276: 3188-94. PMID 11035034 DOI: 10.1074/Jbc.M008099200  0.421
2000 Nasir J, Lafuente MJ, Duan K, Colomer V, Engelender S, Ingersoll R, Margolis RL, Ross CA, Hayden MR. Human huntingtin-associated protein (HAP-1) gene: genomic organisation and an intragenic polymorphism. Gene. 254: 181-7. PMID 10974549 DOI: 10.1016/S0378-1119(00)00269-9  0.657
2000 Wood JD, Nucifora FC, Duan K, Zhang C, Wang J, Kim Y, Schilling G, Sacchi N, Liu JM, Ross CA. Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription. The Journal of Cell Biology. 150: 939-48. PMID 10973986 DOI: 10.1083/Jcb.150.5.939  0.372
2000 Engelender S, Wanner T, Kleiderlein JJ, Wakabayashi K, Tsuji S, Takahashi H, Ashworth R, Margolis RL, Ross CA. Organization of the human synphilin-1 gene, a candidate for Parkinson's disease. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 763-6. PMID 10967135 DOI: 10.1007/S003350010123  0.69
2000 McInnis MG, Swift-Scanlanl T, Mahoney AT, Vincent J, Verheyen G, Lan TH, Oruc L, Riess O, Van Broeckhoven C, Chen H, Kennedy JL, MacKinnon DF, Margolis RL, Simpson SG, McMahon FJ, ... ... Ross CA, et al. Allelic distribution of CTG18.1 in Caucasian populations: association studies in bipolar disorder, schizophrenia, and ataxia. Molecular Psychiatry. 5: 439-42. PMID 10889556 DOI: 10.1038/Sj.Mp.4000747  0.312
2000 Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 1375-9. PMID 10877830 DOI: 10.1096/Fj.14.10.1375  0.64
2000 Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, Frey AS, Spektor BS, Penney EB, Schilling G, Ross CA, Borchelt DR, Tapscott SJ, Young AB, Cha JH, et al. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Human Molecular Genetics. 9: 1259-71. PMID 10814708 DOI: 10.1093/Hmg/9.9.1259  0.547
2000 Wu X, Hepner K, Castelino-Prabhu S, Do D, Kaye MB, Yuan XJ, Wood J, Ross C, Sawyers CL, Whang YE. Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2. Proceedings of the National Academy of Sciences of the United States of America. 97: 4233-8. PMID 10760291 DOI: 10.1073/Pnas.97.8.4233  0.302
2000 Rigamonti D, Bauer JH, De-Fraja C, Conti L, Sipione S, Sciorati C, Clementi E, Hackam A, Hayden MR, Li Y, Cooper JK, Ross CA, Govoni S, Vincenz C, Cattaneo E. Wild-Type Huntingtin Protects from Apoptosis Upstream of Caspase-3 The Journal of Neuroscience. 20: 3705-3713. DOI: 10.1523/Jneurosci.20-10-03705.2000  0.372
2000 Blackshaw S, Sawa A, Sharp AH, Ross CA, Snyder SH, Khan AA. Type 3 inositol 1,4,5‐trisphosphate receptor modulates cell death The Faseb Journal. 14: 1375-1379. DOI: 10.1096/fasebj.14.10.1375  0.599
2000 Ross C. 183. Mouse models of Huntington’s disease Biological Psychiatry. 47: S55. DOI: 10.1016/S0006-3223(00)00446-7  0.315
2000 Wakabayashi K, Engelender S, Yoshimoto M, Tsuji S, Ross CA, Takahashi H. Synphilin-1 is present in Lewy bodies in Parkinson's disease Annals of Neurology. 47: 521-523. DOI: 10.1002/1531-8249(200004)47:4<521::Aid-Ana18>3.0.Co;2-B  0.653
1999 Schilling G, Wood JD, Duan K, Slunt HH, Gonzales V, Yamada M, Cooper JK, Margolis RL, Jenkins NA, Copeland NG, Takahashi H, Tsuji S, Price DL, Borchelt DR, Ross CA. Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA. Neuron. 24: 275-86. PMID 10677044 DOI: 10.1016/S0896-6273(00)80839-9  0.381
1999 Peters MF, Ross CA. Preparation of human cDNas encoding expanded polyglutamine repeats. Neuroscience Letters. 275: 129-32. PMID 10568516 DOI: 10.1016/S0304-3940(99)00758-2  0.35
1999 Margolis RL, McInnis MG, Rosenblatt A, Ross CA. Trinucleotide repeat expansion and neuropsychiatric disease. Archives of General Psychiatry. 56: 1019-31. PMID 10565502 DOI: 10.1001/Archpsyc.56.11.1019  0.365
1999 Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF, Greenamyre JT, Snyder SH, Ross CA. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nature Medicine. 5: 1194-8. PMID 10502825 DOI: 10.1038/13518  0.597
1999 Peters MF, Nucifora FC, Kushi J, Seaman HC, Cooper JK, Herring WJ, Dawson VL, Dawson TM, Ross CA. Nuclear targeting of mutant Huntingtin increases toxicity. Molecular and Cellular Neurosciences. 14: 121-8. PMID 10479410 DOI: 10.1006/Mcne.1999.0773  0.532
1999 Ross CA, Wood JD, Schilling G, Peters MF, Nucifora FC, Cooper JK, Sharp AH, Margolis RL, Borchelt DR. Polyglutamine pathogenesis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1005-11. PMID 10434299 DOI: 10.1098/rstb.1999.0452  0.312
1999 Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nature Genetics. 22: 110-4. PMID 10319874 DOI: 10.1038/8820  0.757
1999 Sharp AH, Nucifora FC, Blondel O, Sheppard CA, Zhang C, Snyder SH, Russell JT, Ryugo DK, Ross CA. Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain. The Journal of Comparative Neurology. 406: 207-20. PMID 10096607 DOI: 10.1002/(Sici)1096-9861(19990405)406:2<207::Aid-Cne6>3.0.Co;2-7  0.458
1999 Nasir J, Maclean A, Engelender S, Duan K, Margolis RL, Kleiderlein JJ, Ross CA, Hayden MR. Chromosomal localization of the Huntingtin associated protein (HAP-1) gene in mouse and humans with radiation hybrid and interspecific backcross mapping. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 397-8. PMID 10087300 DOI: 10.1007/S003359901009  0.627
1999 Margolis RL, Stine OC, Ward CM, Franz ML, Rosenblatt A, Callahan C, Sherr M, Ross CA, Potter NT. Unstable expansion of the CAG trinucleotide repeat in MAB21L1: report of a second pedigree and effect on protein expression. Journal of Medical Genetics. 36: 62-4. PMID 9950369 DOI: 10.1136/Jmg.36.1.62  0.334
1999 Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, Kotzuk JA, Slunt HH, Ratovitski T, Cooper JK, Jenkins NA, Copeland NG, Price DL, Ross CA, Borchelt DR. Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin. Human Molecular Genetics. 8: 397-407. PMID 9949199 DOI: 10.1093/Hmg/8.3.397  0.343
1999 Margolis RL, Stine OC, Callahan C, Rosenblatt A, Abbott MH, Sherr M, Ross CA. Two novel single-base-pair substitutions adjacent to the CAG repeat in the huntington disease gene (IT15): implications for diagnostic testing. American Journal of Human Genetics. 64: 323-6. PMID 9915978 DOI: 10.1086/302209  0.313
1998 Ross CA, Margolis RL, Becher MW, Wood JD, Engelender S, Cooper JK, Sharp AH. Pathogenesis of neurodegenerative diseases associated with expanded glutamine repeats: new answers, new questions. Progress in Brain Research. 117: 397-419. PMID 9932422 DOI: 10.1016/S0079-6123(08)64029-7  0.717
1998 Rosenblatt A, Margolis RL, Becher MW, Aylward E, Franz ML, Sherr M, Abbott MH, Lian KY, Ross CA. Does CAG repeat number predict the rate of pathological changes in Huntington's disease? Annals of Neurology. 44: 708-9. PMID 9778276 DOI: 10.1002/Ana.410440424  0.3
1998 Bengel D, Balling U, Stöber G, Heils A, Li SH, Ross CA, Jungkunz G, Franzek E, Beckmann H, Riederer P, Lesch KP. Distribution of the B33 CTG repeat polymorphism in a subtype of schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 248: 78-81. PMID 9684916 DOI: 10.1007/S004060050021  0.303
1998 Rosenblatt A, Ranen NG, Rubinsztein DC, Stine OC, Margolis RL, Wagster MV, Becher MW, Rosser AE, Leggo J, Hodges JR, ffrench-Constant CK, Sherr M, Franz ML, Abbott MH, Ross CA. Patients with features similar to Huntington's disease, without CAG expansion in huntingtin. Neurology. 51: 215-20. PMID 9674805 DOI: 10.1212/Wnl.51.1.215  0.344
1998 Becher MW, Kotzuk JA, Sharp AH, Davies SW, Bates GP, Price DL, Ross CA. Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length. Neurobiology of Disease. 4: 387-97. PMID 9666478 DOI: 10.1006/Nbdi.1998.0168  0.401
1998 Nasir J, Duan K, Nichol K, Engelender S, Ashworth R, Colomer V, Thomas S, Disteche CM, Hayden MR, Ross CA. Gene structure and map location of the murine homolog of the Huntington-associated protein, Hap1. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 565-70. PMID 9657855 DOI: 10.1007/S003359900819  0.653
1998 Wood JD, Yuan J, Margolis RL, Colomer V, Duan K, Kushi J, Kaminsky Z, Kleiderlein JJ, Sharp AH, Ross CA. Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins. Molecular and Cellular Neurosciences. 11: 149-60. PMID 9647693 DOI: 10.1006/Mcne.1998.0677  0.31
1998 Bertaux F, Sharp AH, Ross CA, Lehrach H, Bates GP, Wanker E. HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice. Febs Letters. 426: 229-32. PMID 9599014 DOI: 10.1016/S0014-5793(98)00352-4  0.397
1998 Cooper JK, Schilling G, Peters MF, Herring WJ, Sharp AH, Kaminsky Z, Masone J, Khan FA, Delanoy M, Borchelt DR, Dawson VL, Dawson TM, Ross CA. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Human Molecular Genetics. 7: 783-90. PMID 9536081 DOI: 10.1093/Hmg/7.5.783  0.521
1998 Wellington CL, Ellerby LM, Hackam AS, Margolis RL, Trifiro MA, Singaraja R, McCutcheon K, Salvesen GS, Propp SS, Bromm M, Rowland KJ, Zhang T, Rasper D, Roy S, Thornberry N, ... ... Ross CA, et al. Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract. The Journal of Biological Chemistry. 273: 9158-67. PMID 9535906 DOI: 10.1074/Jbc.273.15.9158  0.39
1997 Ross CA. Intranuclear neuronal inclusions: A common pathogenic mechanism for glutamine-repeat neurodegenerative diseases? Neuron. 19: 1147-1150. PMID 9427237 DOI: 10.1016/S0896-6273(00)80405-5  0.418
1997 Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Human Molecular Genetics. 6: 2205-12. PMID 9361024 DOI: 10.1093/Hmg/6.13.2205  0.73
1997 Ross CA, Margolis RL, Rosenblatt A, Ranen NG, Becher MW, Aylward E. Huntington disease and the related disorder, dentatorubral-pallidoluysian atrophy (DRPLA). Medicine. 76: 305-38. PMID 9352736 DOI: 10.1097/00005792-199709000-00001  0.313
1997 Cameron AM, Nucifora FC, Fung ET, Livingston DJ, Aldape RA, Ross CA, Snyder SH. FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain. The Journal of Biological Chemistry. 272: 27582-8. PMID 9346894 DOI: 10.1074/Jbc.272.44.27582  0.409
1997 Breschel TS, McInnis MG, Margolis RL, Sirugo G, Corneliussen B, Simpson SG, McMahon FJ, MacKinnon DF, Xu JF, Pleasant N, Huo Y, Ashworth RG, Grundstrom C, Grundstrom T, Kidd KK, ... ... Ross CA, et al. A novel, heritable, expanding CTG repeat in an intron of the SEF2-1 gene on chromosome 18q21.1. Human Molecular Genetics. 6: 1855-63. PMID 9302263 DOI: 10.1093/Hmg/6.11.1855  0.322
1997 Colomer V, Engelender S, Sharp AH, Duan K, Cooper JK, Lanahan A, Lyford G, Worley P, Ross CA. Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain. Human Molecular Genetics. 6: 1519-25. PMID 9285789 DOI: 10.1093/Hmg/6.9.1519  0.723
1997 Davies SW, Turmaine M, Cozens BA, DiFiglia M, Sharp AH, Ross CA, Scherzinger E, Wanker EE, Mangiarini L, Bates GP. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell. 90: 537-48. PMID 9267033 DOI: 10.1016/S0092-8674(00)80513-9  0.408
1997 Becher MW, Rubinsztein DC, Leggo J, Wagster MV, Stine OC, Ranen NG, Franz ML, Abbott MH, Sherr M, MacMillan JC, Barron L, Porteous M, Harper PS, Ross CA. Dentatorubral and pallidoluysian atrophy (DRPLA). Clinical and neuropathological findings in genetically confirmed North American and European pedigrees. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 519-30. PMID 9251070 DOI: 10.1002/Mds.870120408  0.328
1997 Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA. cDNAs with long CAG trinucleotide repeats from human brain. Human Genetics. 100: 114-22. PMID 9225980 DOI: 10.1007/S004390050476  0.404
1997 Ross CA, Becher MW, Colomer V, Engelender S, Wood JD, Sharp AH. Huntington's disease and dentatorubral-pallidoluysian atrophy: proteins, pathogenesis and pathology. Brain Pathology (Zurich, Switzerland). 7: 1003-16. PMID 9217980 DOI: 10.1111/J.1750-3639.1997.Tb00898.X  0.697
1997 Ranen NG, Lipsey JR, Treisman G, Ross CA. Sertraline in the treatment of severe aggressiveness in Huntington's disease. The Journal of Neuropsychiatry and Clinical Neurosciences. 8: 338-40. PMID 8854307 DOI: 10.1176/Jnp.8.3.338  0.307
1996 Khan FA, Margolis RL, Loev SL, Sharp AH, Li SH, Ross CA. cDNA cloning and characterization of an atrophin-1 (DRPLA disease gene)-related protein. Neurobiology of Disease. 3: 121-8. PMID 9173919 DOI: 10.1006/Nbdi.1996.0012  0.346
1996 Sharp AH, Ross CA. Neurobiology of Huntington's disease Neurobiology of Disease. 3: 3-15. PMID 9173909 DOI: 10.1006/Nbdi.1996.0002  0.33
1996 Margolis RL, Li SH, Young WS, Wagster MV, Stine OC, Kidwai AS, Ashworth RG, Ross CA. DRPLA gene (atrophin-1) sequence and mRNA expression in human brain. Brain Research. Molecular Brain Research. 36: 219-26. PMID 8965642 DOI: 10.1016/0169-328X(95)00241-J  0.326
1996 Brando LJ, Yolken R, Herman MM, Kleinman JE, Ross CA, Torrey EF. Analysis of the DRPLA triplet repeat in brain tissue and leukocytes from schizophrenics. Psychiatric Genetics. 6: 1-5. PMID 8925251 DOI: 10.1097/00041444-199621000-00001  0.333
1996 Ranen NG, Peyser CE, Coyle JT, Bylsma FW, Sherr M, Day L, Folstein MF, Brandt J, Ross CA, Folstein SE. A controlled trial of idebenone in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 11: 549-54. PMID 8866496 DOI: 10.1002/Mds.870110510  0.322
1996 Margolis RL, Stine OC, McInnis MG, Ranen NG, Rubinsztein DC, Leggo J, Brando LV, Kidwai AS, Loev SJ, Breschel TS, Callahan C, Simpson SG, DePaulo JR, McMahon FJ, Jain S, ... ... Ross CA, et al. cDNA cloning of a human homologue of the Caenorhabditis elegans cell fate-determining gene mab-21: expression, chromosomal localization and analysis of a highly polymorphic (CAG)n trinucleotide repeat. Human Molecular Genetics. 5: 607-16. PMID 8733127 DOI: 10.1093/Hmg/5.5.607  0.354
1996 Jain S, Leggo J, DeLisi LE, Crow TJ, Margolis RL, Li SH, Goodburn S, Walsh C, Paykel ES, Ferguson-Smith MA, Ross CA, Rubinsztein DC. Analysis of thirteen trinucleotide repeat loci as candidate genes for schizophrenia and bipolar affective disorder. American Journal of Medical Genetics. 67: 139-46. PMID 8723040 DOI: 10.1002/(Sici)1096-8628(19960409)67:2<139::Aid-Ajmg3>3.0.Co;2-N  0.383
1996 Pearlson GD, Petty RG, Ross CA, Tien AY. Schizophrenia: A disease of heteromodal association cortex? Neuropsychopharmacology. 14: 1-17. PMID 8719025 DOI: 10.1016/S0893-133X(96)80054-6  0.32
1996 Khan AA, Soloski MJ, Sharp AH, Schilling G, Sabatini DM, Li SH, Ross CA, Snyder SH. Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science (New York, N.Y.). 273: 503-7. PMID 8662540 DOI: 10.1126/Science.273.5274.503  0.57
1996 Bao J, Sharp AH, Wagster MV, Becher M, Schilling G, Ross CA, Dawson VL, Dawson TM. Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. Proceedings of the National Academy of Sciences of the United States of America. 93: 5037-42. PMID 8643525 DOI: 10.1073/Pnas.93.10.5037  0.535
1996 Li XJ, Sharp AH, Li SH, Dawson TM, Snyder SH, Ross CA. Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 93: 4839-44. PMID 8643490 DOI: 10.1073/Pnas.93.10.4839  0.578
1996 Brandt J, Bylsma FW, Gross R, Stine OC, Ranen N, Ross CA. Trinucleotide repeat length and clinical progression in Huntington's disease Neurology. 46: 527-531. PMID 8614526 DOI: 10.1212/Wnl.46.2.527  0.321
1996 Sasaki T, Billett E, Petronis A, Ying D, Parsons T, Macciardi FM, Meltzer HY, Lieberman J, Joffe RT, Ross CA, McInnis MG, Li SH, Kennedy JL. Psychosis and genes with trinucleotide repeat polymorphism. Human Genetics. 97: 244-6. PMID 8566962 DOI: 10.1007/Bf02265274  0.306
1996 Nucifora FC, Li SH, Danoff S, Ullrich A, Ross CA. Molecular cloning of a cDNA for the human inositol 1,4,5-trisphosphate receptor type 1, and the identification of a third alternatively spliced variant. Brain Research. Molecular Brain Research. 32: 291-6. PMID 7500840 DOI: 10.1016/0169-328X(95)00089-B  0.307
1995 Loev SJ, Margolis RL, Young WS, Li SH, Schilling G, Ashworth RG, Ross CA. Cloning and expression of the rat atrophin-I (DRPLA disease gene) homologue. Neurobiology of Disease. 2: 129-38. PMID 9173996 DOI: 10.1006/Nbdi.1995.0014  0.364
1995 Margolis RL, Breschel TS, Li SH, Kidwai AS, Antonarakis SE, McInnis MG, Ross CA. Characterization of cDNA clones containing CCA trinucleotide repeats derived from human brain. Somatic Cell and Molecular Genetics. 21: 279-84. PMID 8525433 DOI: 10.1007/Bf02255782  0.351
1995 Stine OC, Li SH, Pleasant N, Wagster MV, Hedreen JC, Ross CA. Expression of the mutant allele of IT-15 (the HD gene) in striatum and cortex of Huntington's disease patients. Human Molecular Genetics. 4: 15-8. PMID 7711729 DOI: 10.1093/Hmg/4.1.15  0.372
1995 Schilling G, Sharp AH, Loev SJ, Wagster MV, Li SH, Stine OC, Ross CA. Expression of the Huntington's disease (IT15) protein product in HD patients. Human Molecular Genetics. 4: 1365-71. PMID 7581375 DOI: 10.1093/Hmg/4.8.1365  0.406
1995 Margolis RL, Breschel TS, Li SH, Kidwai AS, McInnis MG, Ross CA. Polymorphic (AAT) in trinucleotide repeats derived from a human brain cDNA library. Human Genetics. 96: 495-6. PMID 7557981 DOI: 10.1007/Bf00191817  0.333
1995 Ross CA. When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases Neuron. 15: 493-496. PMID 7546729 DOI: 10.1016/0896-6273(95)90138-8  0.35
1995 Li XJ, Li SH, Sharp AH, Nucifora FC, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA. A huntingtin-associated protein enriched in brain with implications for pathology. Nature. 378: 398-402. PMID 7477378 DOI: 10.1038/378398A0  0.643
1994 Danoff SK, Ross CA. The inositol trisphosphate receptor gene family: implications for normal and abnormal brain function. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 18: 1-16. PMID 8115665 DOI: 10.1016/0278-5846(94)90021-3  0.314
1994 Paschen W, Blackstone CD, Huganir RL, Ross CA. Human GluR6 kainate receptor (GRIK2): molecular cloning, expression, polymorphism, and chromosomal assignment. Genomics. 20: 435-40. PMID 8034316 DOI: 10.1006/Geno.1994.1198  0.308
1994 Lesch KP, Stöber G, Balling U, Franzek E, Li SH, Ross CA, Newman M, Beckmann H, Riederer P. Triplet repeats in clinical subtypes of schizophrenia: variation at the DRPLA (B37 CAG repeat) locus is not associated with periodic catatonia Journal of Neural Transmission. 98: 153-157. PMID 7734112 DOI: 10.1007/Bf01277018  0.334
1994 Paschen W, Hedreen JC, Ross CA. RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. Journal of Neurochemistry. 63: 1596-602. PMID 7523595 DOI: 10.1046/J.1471-4159.1994.63051596.X  0.327
1994 Wagster MV, Hedreen JC, Peyser CE, Folstein SE, Ross CA. Selective loss of [3H]kainic acid and [3H]AMPA binding in layer VI of frontal cortex in Huntington's disease. Experimental Neurology. 127: 70-5. PMID 7515353 DOI: 10.1006/Exnr.1994.1081  0.301
1993 Duyao M, Ambrose C, Myers R, Novelletto A, Persichetti F, Frontali M, Folstein S, Ross C, Franz M, Abbott M, Gray J, Conneally P, Young A, Penney J, Hollingsworth Z, et al. Trinucleotide repeat length instability and age of onset in Huntington's disease Nature Genetics. 4: 387-392. PMID 8401587 DOI: 10.1038/Ng0893-387  0.354
1993 Schell MJ, Danoff SK, Ross CA. Inositol (1,4,5)-trisphosphate receptor: characterization of neuron-specific alternative splicing in rat brain and peripheral tissues. Brain Research. Molecular Brain Research. 17: 212-6. PMID 8389956 DOI: 10.1016/0169-328X(93)90004-9  0.524
1993 Sharp AH, Dawson TM, Ross CA, Fotuhi M, Mourey RJ, Snyder SH. Inositol 1,4,5-trisphosphate receptors: immunohistochemical localization to discrete areas of rat central nervous system. Neuroscience. 53: 927-42. PMID 8389431 DOI: 10.1016/0306-4522(93)90478-X  0.532
1993 Li SH, McInnis MG, Margolis RL, Antonarakis SE, Ross CA. Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. Genomics. 16: 572-9. PMID 8325628 DOI: 10.1006/Geno.1993.1232  0.355
1993 Ross CA, McInnis MG, Margolis RL, Li SH. Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends in Neurosciences. 16: 254-60. PMID 7689767 DOI: 10.1016/0166-2236(93)90175-L  0.36
1992 Zweig RM, Ross CA, Hedreen JC, Peyser C, Cardillo JE, Folstein SE, Price DL. Locus coeruleus involvement in Huntington's disease. Archives of Neurology. 49: 152-6. PMID 1531288 DOI: 10.1001/Archneur.1992.00530260052019  0.385
1992 Ross CA, Danoff SK, Schell MJ, Snyder SH, Ullrich A. Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues. Proceedings of the National Academy of Sciences of the United States of America. 89: 4265-9. PMID 1374893 DOI: 10.1073/Pnas.89.10.4265  0.575
1991 Danoff SK, Ferris CD, Donath C, Fischer GA, Munemitsu S, Ullrich A, Snyder SH, Ross CA. Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 88: 2951-5. PMID 1849282 DOI: 10.1073/Pnas.88.7.2951  0.645
1991 Hedreen JC, Peyser CE, Folstein SE, Ross CA. Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease. Neuroscience Letters. 133: 257-61. PMID 1840078 DOI: 10.1016/0304-3940(91)90583-F  0.314
1991 Miller KK, Verma A, Snyder SH, Ross CA. Localization of an endoplasmic reticulum calcium ATPase mRNA in rat brain by in situ hybridization. Neuroscience. 43: 1-9. PMID 1833665 DOI: 10.1016/0306-4522(91)90410-P  0.405
1991 Ross CA. CNS Arousal Systems: Possible Role in Delirium International Psychogeriatrics. 3: 353-371. PMID 1687443 DOI: 10.1017/S1041610291000819  0.305
1990 Satoh T, Ross CA, Villa A, Supattapone S, Pozzan T, Snyder SH, Meldolesi J. The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment. The Journal of Cell Biology. 111: 615-24. PMID 2166053 DOI: 10.1083/Jcb.111.2.615  0.601
1990 MacCumber MW, Ross CA, Snyder SH. Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 2359-63. PMID 2156267 DOI: 10.1073/Pnas.87.6.2359  0.417
1990 Verma A, Ross CA, Verma D, Supattapone S, Snyder SH. Rat brain endoplasmic reticulum calcium pools are anatomically and functionally segregated. Cell Regulation. 1: 781-90. PMID 1966012 DOI: 10.1091/Mbc.1.10.781  0.69
1990 Ross CA, Bredt D, Snyder SH. Messenger molecules in the cerebellum. Trends in Neurosciences. 13: 216-22. PMID 1694327 DOI: 10.1016/0166-2236(90)90163-5  0.588
1990 MacCumber M, Snyder S, Ross C. Carboxypeptidase E (enkephalin convertase): mRNA distribution in rat brain by in situ hybridization The Journal of Neuroscience. 10: 2850-2860. DOI: 10.1523/Jneurosci.10-08-02850.1990  0.411
1989 MacCumber MW, Ross CA, Glaser BM, Snyder SH. Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action. Proceedings of the National Academy of Sciences of the United States of America. 86: 7285-9. PMID 2674952 DOI: 10.1073/Pnas.86.18.7285  0.371
1989 Ross CA, Meldolesi J, Milner TA, Satoh T, Supattapone S, Snyder SH. Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons. Nature. 339: 468-70. PMID 2542801 DOI: 10.1038/339468A0  0.64
1989 Ross CA, MacCumber MW, Glatt CE, Snyder SH. Brain phospholipase C isozymes: differential mRNA localizations by in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 86: 2923-7. PMID 2468162 DOI: 10.1073/Pnas.86.8.2923  0.657
1988 Ross CA, Wright GE, Resh MD, Pearson RCA, Snyder SH. Brain-specific src oncogene mRNA mapped in rat brain by in situ hybridization Proceedings of the National Academy of Sciences of the United States of America. 85: 9831-9835. PMID 3200860 DOI: 10.1073/Pnas.85.24.9831  0.429
1988 Zweig RM, Ross CA, Hedreen JC, Steele C, Cardillo JE, Whitehouse PJ, Folstein MF, Price DL. The neuropathology of aminergic nuclei in Alzheimer's disease. Annals of Neurology. 24: 233-42. PMID 3178178 DOI: 10.1002/Ana.410240210  0.311
1988 ZWEIG RM, ROSS CA, HEDREEN JC, STEELE C, CARDILLO JE, WHITEHOUSE PJ, FOLSTEIN MF, PRICE DL. THE NEUROPATHOLOGY OF AMINERGIC NUCLEI IN ALZHEIMER??S DISEASE Alzheimer Disease & Associated Disorders. 2: 231. DOI: 10.1097/00002093-198802030-00080  0.323
1987 Warren AC, Robakis NK, Ramakrishna N, Koo EH, Ross CA, Robb AS, Folstein MF, Price DL, Antonarakis SE. beta-Amyloid gene is not present in three copies in autopsy-validated Alzheimer's disease. Genomics. 1: 307-12. PMID 2966761 DOI: 10.1016/0888-7543(87)90029-2  0.305
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