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Richard Wyatt - Publications

Affiliations: 
1976-1978 University of Iowa, Iowa City, IA 
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89/156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bale S, Yang L, Alirezaei M, Wilson R, Ota T, Doyle ED, Cottrell CA, Guenaga J, Tran K, Li W, Stamatatos L, Nemazee D, Ward AB, Wyatt RT. Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response. Frontiers in Immunology. 14: 1180959. PMID 37283743 DOI: 10.3389/fimmu.2023.1180959  0.353
2021 Aljedani SS, Liban TJ, Tran K, Phad G, Singh S, Dubrovskaya V, Pushparaj P, Martinez-Murillo P, Rodarte J, Mileant A, Mangala Prasad V, Kinzelman R, O'Dell S, Mascola JR, Lee KK, ... ... Wyatt RT, et al. Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization. Plos Pathogens. 17: e1009543. PMID 34559844 DOI: 10.1371/journal.ppat.1009543  0.351
2019 Parks KR, MacCamy AJ, Trichka J, Gray M, Weidle C, Borst AJ, Khechaduri A, Takushi B, Agrawal P, Guenaga J, Wyatt RT, Coler R, Seaman M, LaBranche C, Montefiori DC, et al. Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Reports. 29: 3060-3072.e7. PMID 31801073 DOI: 10.1016/J.Celrep.2019.10.071  0.346
2019 Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vázquez Bernat N, ... ... Wyatt RT, et al. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity. PMID 31732167 DOI: 10.1016/J.Immuni.2019.10.008  0.348
2019 Phad GE, Pushparaj P, Tran K, Dubrovskaya V, Àdori M, Martinez-Murillo P, Vázquez Bernat N, Singh S, Dionne G, O'Dell S, Bhullar K, Narang S, Sorini C, Villablanca EJ, Sundling C, ... ... Wyatt RT, et al. Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. The Journal of Experimental Medicine. PMID 31704807 DOI: 10.1084/Jem.20191155  0.313
2019 Lei L, Yang YR, Tran K, Wang Y, Chiang CI, Ozorowski G, Xiao Y, Ward AB, Wyatt RT, Li Y. The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization. Cell Reports. 27: 586-598.e6. PMID 30970260 DOI: 10.1016/J.Celrep.2019.03.039  0.312
2018 Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer. Nature Communications. 9: 3693. PMID 30209313 DOI: 10.1038/s41467-018-06121-4  0.343
2018 Khan SN, Sok D, Tran K, Movsesyan A, Dubrovskaya V, Burton D, Wyatt RT. Targeting the HIV-1 spike and co-receptor with bi- and trispecific antibodies for single-component broad inhibition of entry. Journal of Virology. PMID 29976677 DOI: 10.1128/JVI.00384-18  0.326
2018 Bale S, Martiné A, Wilson R, Behrens AJ, Le Fourn V, de Val N, Sharma SK, Tran K, Torres JL, Girod PA, Ward AB, Crispin M, Wyatt RT. Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies. Frontiers in Immunology. 9: 1116. PMID 29881382 DOI: 10.3389/Fimmu.2018.01116  0.352
2018 Boliar S, Patil S, Shukla BN, Ghobbeh A, Deshpande S, Chen W, Guenaga J, Dimitrov DS, Wyatt RT, Chakrabarti BK. Ligand accessibility to the HIV-1 Env co-receptor binding site can occur prior to CD4 engagement and is independent of viral tier category. Virology. 519: 99-105. PMID 29684630 DOI: 10.1016/j.virol.2018.04.002  0.304
2017 Soldemo M, Àdori M, Stark JM, Feng Y, Tran K, Wilson R, Yang L, Guenaga J, Wyatt RT, Karlsson Hedestam GB. Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice. Frontiers in Immunology. 8: 1654. PMID 29230223 DOI: 10.3389/Fimmu.2017.01654  0.328
2017 Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 21: 222-235. PMID 28978475 DOI: 10.1016/J.Celrep.2017.09.024  0.355
2017 Dubrovskaya V, Guenaga J, de Val N, Wilson R, Feng Y, Movsesyan A, Karlsson Hedestam GB, Ward AB, Wyatt RT. Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response. Plos Pathogens. 13: e1006614. PMID 28902916 DOI: 10.1371/Journal.Ppat.1006614  0.33
2017 Wang Y, O'Dell S, Turner HL, Chiang CI, Lei L, Guenaga J, Wilson R, Martinez-Murillo P, Doria-Rose N, Ward AB, Mascola JR, Wyatt RT, Karlsson Hedestam GB, Li Y. HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate. Journal of Virology. PMID 28835491 DOI: 10.1128/Jvi.00910-17  0.324
2017 Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Wyatt RT, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007  0.306
2017 Bale S, Goebrecht G, Stano A, Wilson R, Ota T, Tran K, Ingale J, Zwick MB, Wyatt RT. Covalent linkage of HIV-1 trimers to synthetic liposomes elicits improved B cell and antibody responses. Journal of Virology. PMID 28592540 DOI: 10.1128/Jvi.00443-17  0.328
2017 Martinez-Murillo P, Tran K, Guenaga J, Lindgren G, Àdori M, Feng Y, Phad GE, Vázquez Bernat N, Bale S, Ingale J, Dubrovskaya V, O'Dell S, Pramanik L, Spångberg M, Corcoran M, ... ... Wyatt RT, et al. Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach. Immunity. 46: 804-817.e7. PMID 28514687 DOI: 10.1016/J.Immuni.2017.04.021  0.34
2017 Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, ... ... Wyatt RT, et al. Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10. PMID 28514685 DOI: 10.1016/J.Immuni.2017.04.011  0.356
2017 Cai H, Orwenyo J, Guenaga J, Giddens J, Toonstra C, Wyatt RT, Wang LX. Synthetic multivalent V3 glycopeptides display enhanced recognition by glycan-dependent HIV-1 broadly neutralizing antibodies. Chemical Communications (Cambridge, England). PMID 28466900 DOI: 10.1039/C7Cc02059G  0.335
2017 Stano A, Leaman DP, Kim AS, Zhang L, Autin L, Ingale J, Gift SK, Truong J, Wyatt RT, Olson AJ, Zwick MB. Dense array of spikes on HIV-1 virion particles. Journal of Virology. PMID 28446665 DOI: 10.1128/Jvi.00415-17  0.331
2017 Karlsson Hedestam GB, Guenaga J, Corcoran M, Wyatt RT. Evolution of B cell analysis and Env trimer redesign. Immunological Reviews. 275: 183-202. PMID 28133805 DOI: 10.1111/imr.12515  0.355
2016 Chen Y, Wilson R, O'Dell S, Guenaga J, Feng Y, Tran K, Chiang CI, Arendt HE, DeStefano J, Mascola JR, Wyatt RT, Li Y. An HIV-1 Env-Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes. Journal of Immunology (Baltimore, Md. : 1950). 197: 3982-3998. PMID 27815444 DOI: 10.4049/Jimmunol.1601134  0.363
2016 Longo NS, Sutton MS, Shiakolas AR, Guenaga J, Jarosinski MC, Georgiev IS, McKee K, Bailer RT, Louder MK, O'Dell S, Connors M, Wyatt RT, Mascola JR, Doria-Rose NA. Multiple antibody lineages in one donor target the glycan-V3 supersite of the HIV-1 envelope glycoprotein and display a preference for quaternary binding. Journal of Virology. PMID 27654288 DOI: 10.1128/Jvi.01012-16  0.342
2016 Feng Y, Tran K, Bale S, Kumar S, Guenaga J, Wilson R, de Val N, Arendt H, DeStefano J, Ward AB, Wyatt RT. Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies. Plos Pathogens. 12: e1005767. PMID 27487086 DOI: 10.1371/Journal.Ppat.1005767  0.321
2016 Ingale J, Stano A, Guenaga J, Sharma SK, Nemazee D, Zwick MB, Wyatt RT. High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells. Cell Reports. PMID 27210756 DOI: 10.1016/J.Celrep.2016.04.078  0.313
2016 Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, ... ... Wyatt RT, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006  0.338
2016 Mason RD, Welles HC, Adams C, Chakrabarti BK, Gorman J, Zhou T, Nguyen R, O'Dell S, Lusvarghi S, Bewley CA, Li H, Shaw GM, Sheng Z, Shapiro L, Wyatt R, et al. Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. Plos Pathogens. 12: e1005537. PMID 27064278 DOI: 10.1371/Journal.Ppat.1005537  0.384
2016 Wang Y, Sundling C, Wilson R, O'Dell S, Chen Y, Dai K, Phad GE, Zhu J, Xiao Y, Mascola JR, Karlsson Hedestam GB, Wyatt RT, Li Y. High-Resolution Longitudinal Study of HIV-1 Env Vaccine-Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence. Journal of Immunology (Baltimore, Md. : 1950). PMID 27001953 DOI: 10.4049/Jimmunol.1502543  0.332
2016 Dai K, Khan SN, Wang Y, He L, Guenaga J, Ingale J, Sundling C, O'Dell S, McKee K, Phad G, Corcoran M, Wilson R, Mascola JR, Zhu J, Li Y, ... ... Wyatt RT, et al. HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation. Scientific Reports. 6: 20987. PMID 26879974 DOI: 10.1038/srep20987  0.37
2015 Ingale J, Wyatt RT. Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores. Bio-Protocol. 5. PMID 26855965  0.313
2015 Ingale J, Wyatt RT. Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays. Bio-Protocol. 5. PMID 26855964  0.378
2015 Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT. Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers. Journal of Virology. PMID 26719252 DOI: 10.1128/JVI.02652-15  0.306
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, Destefano J, O'Dell S, LaBranche C, Robinson JE, ... ... Wyatt RT, et al. Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site. Plos Pathogens. 11: e1004932. PMID 26023780 DOI: 10.1371/Journal.Ppat.1004932  0.36
2015 Phad GE, Vázquez Bernat N, Feng Y, Ingale J, Martinez Murillo PA, O'Dell S, Li Y, Mascola JR, Sundling C, Wyatt RT, Karlsson Hedestam GB. Diverse antibody genetic and recognition properties revealed following HIV-1 envelope glycoprotein immunization. Journal of Immunology (Baltimore, Md. : 1950). 194: 5903-14. PMID 25964491 DOI: 10.4049/jimmunol.1500122  0.368
2015 Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT. Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design. Cell Reports. 11: 539-50. PMID 25892233 DOI: 10.1016/J.Celrep.2015.03.047  0.314
2015 Martinez P, Sundling C, O'Dell S, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation. Scientific Reports. 5: 8925. PMID 25762407 DOI: 10.1038/srep08925  0.31
2015 Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT. Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties. Plos Pathogens. 11: e1004570. PMID 25569572 DOI: 10.1371/journal.ppat.1004570  0.302
2014 Forsell MN, McKee K, Feng Y, Mascola JR, Wyatt RT. HIV-1 envelope glycoprotein trimer immunogenicity elicited in the presence of human CD4 alters the neutralization profile. Aids Research and Human Retroviruses. 30: 1089-98. PMID 25245278 DOI: 10.1089/AID.2014.0104  0.317
2014 Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, ... ... Wyatt RT, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature. 515: 138-42. PMID 25186731 DOI: 10.1038/Nature13601  0.359
2014 Navis M, Tran K, Bale S, Phad GE, Guenaga J, Wilson R, Soldemo M, McKee K, Sundling C, Mascola J, Li Y, Wyatt RT, Karlsson Hedestam GB. HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization. Plos Pathogens. 10: e1004337. PMID 25166308 DOI: 10.1371/Journal.Ppat.1004337  0.323
2014 Madani N, Princiotto AM, Schön A, LaLonde J, Feng Y, Freire E, Park J, Courter JR, Jones DM, Robinson J, Liao HX, Moody AA, Permar S, Haynes B, Smith AB, ... Wyatt R, et al. CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies Journal of Virology. 88: 6542-6555. PMID 24696475 DOI: 10.1128/Jvi.00540-14  0.383
2014 Tran K, Poulsen C, Guenaga J, de Val N, de Val Alda N, Wilson R, Sundling C, Li Y, Stanfield RL, Wilson IA, Ward AB, Karlsson Hedestam GB, Wyatt RT. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proceedings of the National Academy of Sciences of the United States of America. 111: E738-47. PMID 24550318 DOI: 10.1073/Pnas.1319512111  0.344
2013 Feng Y, Forsell MN, Flynn B, Adams W, Loré K, Seder R, Wyatt RT, Karlsson Hedestam GB. Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants. Virology. 446: 56-65. PMID 24074567 DOI: 10.1016/j.virol.2013.07.028  0.324
2013 Chakrabarti BK, Feng Y, Sharma SK, McKee K, Karlsson Hedestam GB, Labranche CC, Montefiori DC, Mascola JR, Wyatt RT. Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates. Journal of Virology. 87: 13239-51. PMID 24067980 DOI: 10.1128/JVI.01247-13  0.363
2013 Forsell MN, Soldemo M, Dosenovic P, Wyatt RT, Karlsson MC, Karlsson Hedestam GB. Independent expansion of epitope-specific plasma cell responses upon HIV-1 envelope glycoprotein immunization. Journal of Immunology (Baltimore, Md. : 1950). 191: 44-51. PMID 23740950 DOI: 10.4049/jimmunol.1203087  0.306
2012 Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, Alam SM, Wang T, Yang Y, Zhang B, Migueles SA, ... Wyatt R, et al. Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature. 491: 406-12. PMID 23151583 DOI: 10.1038/nature11544  0.368
2012 Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, ... ... Wyatt R, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008  0.309
2012 Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, ... ... Wyatt RT, et al. Anti-HIV B Cell lines as candidate vaccine biosensors. Journal of Immunology (Baltimore, Md. : 1950). 189: 4816-24. PMID 23066156 DOI: 10.4049/Jimmunol.1202165  0.304
2012 Li Y, O'Dell S, Wilson R, Wu X, Schmidt SD, Hogerkorp CM, Louder MK, Longo NS, Poulsen C, Guenaga J, Chakrabarti BK, Doria-Rose N, Roederer M, Connors M, Mascola JR, ... Wyatt RT, et al. HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins. Journal of Virology. 86: 11231-41. PMID 22875963 DOI: 10.1128/JVI.01543-12  0.356
2012 Sundling C, Li Y, Huynh N, Poulsen C, Wilson R, O'Dell S, Feng Y, Mascola JR, Wyatt RT, Karlsson Hedestam GB. High-resolution definition of vaccine-elicited B cell responses against the HIV primary receptor binding site. Science Translational Medicine. 4: 142ra96. PMID 22786681 DOI: 10.1126/scitranslmed.3003752  0.365
2012 Dosenovic P, Soldemo M, Scholz JL, O'Dell S, Grasset EK, Pelletier N, Karlsson MC, Mascola JR, Wyatt RT, Cancro MP, Karlsson Hedestam GB. BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses. Journal of Immunology (Baltimore, Md. : 1950). 188: 6018-26. PMID 22561155 DOI: 10.4049/Jimmunol.1200466  0.319
2012 Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, Shaw GM, Wyatt RT, Mascola JR. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. Journal of Virology. 86: 5844-56. PMID 22419808 DOI: 10.1128/Jvi.07139-11  0.353
2012 Falkowska E, Ramos A, Feng Y, Zhou T, Moquin S, Walker LM, Wu X, Seaman MS, Wrin T, Kwong PD, Wyatt RT, Mascola JR, Poignard P, Burton DR. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4. Journal of Virology. 86: 4394-403. PMID 22345481 DOI: 10.1128/JVI.06973-11  0.324
2012 Feng Y, McKee K, Tran K, O'Dell S, Schmidt SD, Phogat A, Forsell MN, Karlsson Hedestam GB, Mascola JR, Wyatt RT. Biochemically defined HIV-1 envelope glycoprotein variant immunogens display differential binding and neutralizing specificities to the CD4-binding site. The Journal of Biological Chemistry. 287: 5673-86. PMID 22167180 DOI: 10.1074/jbc.M111.317776  0.373
2011 Li Y, O'Dell S, Walker LM, Wu X, Guenaga J, Feng Y, Schmidt SD, McKee K, Louder MK, Ledgerwood JE, Graham BS, Haynes BF, Burton DR, Wyatt RT, Mascola JR. Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01. Journal of Virology. 85: 8954-67. PMID 21715490 DOI: 10.1128/Jvi.00754-11  0.344
2011 Mörner A, Jansson M, Bunnik EM, Schøller J, Vaughan R, Wang Y, Montefiori DC, Otting N, Bontrop R, Bergmeier LA, Singh M, Wyatt RT, Schuitemaker H, Biberfeld G, Thorstensson R, et al. Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques. Journal of Virology. 85: 6442-52. PMID 21490092 DOI: 10.1128/JVI.00129-11  0.333
2011 Guenaga J, Dosenovic P, Ofek G, Baker D, Schief WR, Kwong PD, Karlsson Hedestam GB, Wyatt RT. Heterologous epitope-scaffold prime:boosting immuno-focuses B cell responses to the HIV-1 gp41 2F5 neutralization determinant. Plos One. 6: e16074. PMID 21297864 DOI: 10.1371/Journal.Pone.0016074  0.332
2011 Chakrabarti BK, Pancera M, Phogat S, O'Dell S, McKee K, Guenaga J, Robinson J, Mascola J, Wyatt RT. HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies. Aids Research and Human Retroviruses. 27: 877-87. PMID 21158699 DOI: 10.1089/AID.2010.0281  0.312
2010 Sundling C, Forsell MN, O'Dell S, Feng Y, Chakrabarti B, Rao SS, Loré K, Mascola JR, Wyatt RT, Douagi I, Karlsson Hedestam GB. Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates. The Journal of Experimental Medicine. 207: 2003-17. PMID 20679401 DOI: 10.1084/jem.20100025  0.368
2010 Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, ... ... Wyatt RT, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science (New York, N.Y.). 329: 856-61. PMID 20616233 DOI: 10.1126/Science.1187659  0.373
2010 Douagi I, Forsell MN, Sundling C, O'Dell S, Feng Y, Dosenovic P, Li Y, Seder R, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates. Journal of Virology. 84: 1683-95. PMID 19955308 DOI: 10.1128/JVI.01896-09  0.307
2010 Doria-Rose NA, Klein RM, Daniels MG, O'Dell S, Nason M, Lapedes A, Bhattacharya T, Migueles SA, Wyatt RT, Korber BT, Mascola JR, Connors M. Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables. Journal of Virology. 84: 1631-6. PMID 19923174 DOI: 10.1128/Jvi.01482-09  0.302
2009 Chen L, Kwon YD, Zhou T, Wu X, O'Dell S, Cavacini L, Hessell AJ, Pancera M, Tang M, Xu L, Yang ZY, Zhang MY, Arthos J, Burton DR, Dimitrov DS, ... ... Wyatt R, et al. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science (New York, N.Y.). 326: 1123-7. PMID 19965434 DOI: 10.1126/Science.1175868  0.373
2009 Dosenovic P, Chakrabarti B, Soldemo M, Douagi I, Forsell MN, Li Y, Phogat A, Paulie S, Hoxie J, Wyatt RT, Karlsson Hedestam GB. Selective expansion of HIV-1 envelope glycoprotein-specific B cell subsets recognizing distinct structural elements following immunization. Journal of Immunology (Baltimore, Md. : 1950). 183: 3373-82. PMID 19696434 DOI: 10.4049/Jimmunol.0900407  0.316
2009 Dey B, Svehla K, Xu L, Wycuff D, Zhou T, Voss G, Phogat A, Chakrabarti BK, Li Y, Shaw G, Kwong PD, Nabel GJ, Mascola JR, Wyatt RT. Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. Plos Pathogens. 5: e1000445. PMID 19478876 DOI: 10.1371/Journal.Ppat.1000445  0.302
2009 Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, Phogat A, Chakrabarti B, Li Y, Connors M, Pereyra F, ... ... Wyatt RT, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature. 458: 636-40. PMID 19287373 DOI: 10.1038/Nature07930  0.362
2009 Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, Seaman MS, Mascola JR, Wyatt RT, Wardemann H, Nussenzweig MC. A method for identification of HIV gp140 binding memory B cells in human blood. Journal of Immunological Methods. 343: 65-7. PMID 19100741 DOI: 10.1016/J.Jim.2008.11.012  0.307
2009 Mörner A, Douagi I, Forsell MNE, Sundling C, Dosenovic P, O'Dell S, Dey B, Kwong PD, Voss G, Thorstensson R, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Human immunodeficiency virus type 1 Env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein Journal of Virology. 83: 540-551. PMID 19004960 DOI: 10.1128/JVI.01102-08  0.313
2009 Li Y, Svehla K, Louder MK, Wycuff D, Phogat S, Tang M, Migueles SA, Wu X, Phogat A, Shaw GM, Connors M, Hoxie J, Mascola JR, Wyatt R. Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals. Journal of Virology. 83: 1045-59. PMID 19004942 DOI: 10.1128/Jvi.01992-08  0.39
2009 Doria-Rose NA, Klein RM, Manion MM, O'Dell S, Phogat A, Chakrabarti B, Hallahan CW, Migueles SA, Wrammert J, Ahmed R, Nason M, Wyatt RT, Mascola JR, Connors M. Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. Journal of Virology. 83: 188-99. PMID 18922865 DOI: 10.1128/Jvi.01583-08  0.357
2008 Sundling C, Schön K, Mörner A, Forsell MN, Wyatt RT, Thorstensson R, Karlsson Hedestam GB, Lycke NY. CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization. The Journal of General Virology. 89: 2954-64. PMID 19008380 DOI: 10.1099/vir.0.2008/005470-0  0.313
2008 Forsell MN, Dey B, Mörner A, Svehla K, O'dell S, Högerkorp CM, Voss G, Thorstensson R, Shaw GM, Mascola JR, Karlsson Hedestam GB, Wyatt RT. B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4. Plos Pathogens. 4: e1000171. PMID 18833294 DOI: 10.1371/journal.ppat.1000171  0.329
2008 Selvarajah S, Puffer BA, Lee FH, Zhu P, Li Y, Wyatt R, Roux KH, Doms RW, Burton DR. Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. Aids Research and Human Retroviruses. 24: 301-14. PMID 18284327 DOI: 10.1089/Aid.2007.0158  0.304
2007 Huang CC, Lam SN, Acharya P, Tang M, Xiang SH, Hussan SS, Stanfield RL, Robinson J, Sodroski J, Wilson IA, Wyatt R, Bewley CA, Kwong PD. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science (New York, N.Y.). 317: 1930-4. PMID 17901336 DOI: 10.1126/Science.1145373  0.341
2007 Li Y, Migueles SA, Welcher B, Svehla K, Phogat A, Louder MK, Wu X, Shaw GM, Connors M, Wyatt RT, Mascola JR. Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nature Medicine. 13: 1032-4. PMID 17721546 DOI: 10.1038/nm1624  0.331
2007 Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature. 445: 732-7. PMID 17301785 DOI: 10.1038/Nature05580  0.351
2006 Bower JF, Li Y, Wyatt R, Ross TM. HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies. Vaccine. 24: 5442-51. PMID 16621193 DOI: 10.1016/J.Vaccine.2006.03.063  0.37
2005 Huang CC, Tang M, Zhang MY, Majeed S, Montabana E, Stanfield RL, Dimitrov DS, Korber B, Sodroski J, Wilson IA, Wyatt R, Kwong PD. Structural biology: Structure of a V3-containing HIV-1 gp120 core Science. 310: 1025-1028. PMID 16284180 DOI: 10.1126/Science.1118398  0.333
2005 Forsell MN, Li Y, Sundbäck M, Svehla K, Liljeström P, Mascola JR, Wyatt R, Karlsson Hedestam GB. Biochemical and immunogenic characterization of soluble human immunodeficiency virus type 1 envelope glycoprotein trimers expressed by semliki forest virus. Journal of Virology. 79: 10902-14. PMID 16103142 DOI: 10.1128/JVI.79.17.10902-10914.2005  0.369
2005 Pancera M, Wyatt R. Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage. Virology. 332: 145-56. PMID 15661147 DOI: 10.1016/j.virol.2004.10.042  0.37
2005 Grundner C, Li Y, Louder M, Mascola J, Yang X, Sodroski J, Wyatt R. Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins. Virology. 331: 33-46. PMID 15582651 DOI: 10.1016/J.Virol.2004.09.022  0.37
2004 Grundner C, Pancera M, Kang JM, Koch M, Sodroski J, Wyatt R. Factors limiting the immunogenicity of HIV-1 gp120 envelope glycoproteins. Virology. 330: 233-48. PMID 15527849 DOI: 10.1016/J.Virol.2004.08.037  0.371
2004 Ofek G, Tang M, Sambor A, Katinger H, Mascola JR, Wyatt R, Kwong PD. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. Journal of Virology. 78: 10724-37. PMID 15367639 DOI: 10.1128/JVI.78.19.10724-10737.2004  0.31
2004 Brainard DM, Tharp WG, Granado E, Miller N, Trocha AK, Ren XH, Conrad B, Terwilliger EF, Wyatt R, Walker BD, Poznansky MC. Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120. Journal of Virology. 78: 5184-93. PMID 15113900 DOI: 10.1128/Jvi.78.10.5184-5193.2004  0.339
2004 Huang CC, Venturi M, Majeed S, Moore MJ, Phogat S, Zhang MY, Dimitrov DS, Hendrickson WA, Robinson J, Sodroski J, Wyatt R, Choe H, Farzan M, Kwong PD. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proceedings of the National Academy of Sciences of the United States of America. 101: 2706-2711. PMID 14981267 DOI: 10.1073/Pnas.0308527100  0.35
2003 Labrijn AF, Poignard P, Raja A, Zwick MB, Delgado K, Franti M, Binley J, Vivona V, Grundner C, Huang CC, Venturi M, Petropoulos CJ, Wrin T, Dimitrov DS, Robinson J, ... ... Wyatt RT, et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. Journal of Virology. 77: 10557-65. PMID 12970440 DOI: 10.1128/Jvi.77.19.10557-10565.2003  0.379
2003 Koch M, Pancera M, Kwong PD, Kolchinsky P, Grundner C, Wang L, Hendrickson WA, Sodroski J, Wyatt R. Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition Virology. 313: 387-400. PMID 12954207 DOI: 10.1016/S0042-6822(03)00294-0  0.368
2002 Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, ... ... Wyatt R, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/Nature01188  0.325
2002 Grundner C, Mirzabekov T, Sodroski J, Wyatt R. Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins. Journal of Virology. 76: 3511-21. PMID 11884575 DOI: 10.1128/Jvi.76.7.3511-3521.2002  0.39
Low-probability matches (unlikely to be authored by this person)
2013 Ota T, Doyle-Cooper C, Cooper AB, Doores KJ, Aoki-Ota M, Le K, Schief WR, Wyatt RT, Burton DR, Nemazee D. B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates. Journal of Immunology (Baltimore, Md. : 1950). 191: 3179-85. PMID 23940273 DOI: 10.4049/Jimmunol.1301283  0.3
2014 Ingale J, Tran K, Kong L, Dey B, McKee K, Schief W, Kwong PD, Mascola JR, Wyatt RT. Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. Journal of Virology. 88: 14002-16. PMID 25253346 DOI: 10.1128/JVI.02614-14  0.298
2017 Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT. Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity. 46: 792-803.e3. PMID 28514686 DOI: 10.1016/J.Immuni.2017.04.014  0.298
2002 Yang X, Lee J, Mahony EM, Kwong PD, Wyatt R, Sodroski J. Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin Journal of Virology. 76: 4634-4642. PMID 11932429 DOI: 10.1128/Jvi.76.9.4634-4642.2002  0.296
2009 Forsell MN, Schief WR, Wyatt RT. Immunogenicity of HIV-1 envelope glycoprotein oligomers. Current Opinion in Hiv and Aids. 4: 380-7. PMID 20048701 DOI: 10.1097/COH.0b013e32832edc19  0.296
2018 Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Wyatt RT, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011  0.296
2015 Dai K, He L, Khan SN, O'Dell S, McKee K, Tran K, Li Y, Sundling C, Morris CD, Mascola JR, Karlsson Hedestam GB, Wyatt RT, Zhu J. Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis. Mbio. 6. PMID 26530382 DOI: 10.1128/mBio.01375-15  0.294
2018 Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 22: 1103. PMID 29386130 DOI: 10.1016/j.celrep.2017.10.089  0.292
2018 Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nature Communications. 9: 1956. PMID 29769533 DOI: 10.1038/S41467-018-04272-Y  0.291
2002 Xiang SH, Kwong PD, Gupta R, Rizzuto CD, Casper DJ, Wyatt R, Wang L, Hendrickson WA, Doyle ML, Sodroski J. Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein Journal of Virology. 76: 9888-9899. PMID 12208966 DOI: 10.1128/Jvi.76.19.9888-9899.2002  0.288
2004 Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nature Immunology. 5: 233-6. PMID 14985706 DOI: 10.1038/Ni0304-233  0.287
2010 Sundling C, O'Dell S, Douagi I, Forsell MN, Mörner A, Loré K, Mascola JR, Wyatt RT, Karlsson Hedestam GB. Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus. Journal of Virology. 84: 9086-95. PMID 20610729 DOI: 10.1128/JVI.01015-10  0.285
2009 Wu X, Zhou T, O'Dell S, Wyatt RT, Kwong PD, Mascola JR. Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment. Journal of Virology. 83: 10892-907. PMID 19692465 DOI: 10.1128/JVI.01142-09  0.285
2019 Damm D, Rojas-Sánchez L, Theobald H, Sokolova V, Wyatt RT, Überla K, Epple M, Temchura V. Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help. Nanomaterials (Basel, Switzerland). 9. PMID 31569763 DOI: 10.3390/nano9101389  0.284
2005 Huang CC, Stricher F, Martin L, Decker JM, Majeed S, Barthe P, Hendrickson WA, Robinson J, Roumestand C, Sodroski J, Wyatt R, Shaw GM, Vita C, Kwong PD. Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120: Crystal structures, molecular mimicry, and neutralization breadth Structure. 13: 755-768. PMID 15893666 DOI: 10.1016/J.Str.2005.03.006  0.284
2013 Sandgren KJ, Smed-Sörensen A, Forsell MN, Soldemo M, Adams WC, Liang F, Perbeck L, Koup RA, Wyatt RT, Karlsson Hedestam GB, Loré K. Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 191: 60-9. PMID 23729440 DOI: 10.4049/jimmunol.1202489  0.281
2005 Koch M, Frazier J, Sodroski J, Wyatt R. Characterization of antibody responses to purified HIV-1 gp120 glycoproteins fused with the molecular adjuvant C3d Virology. 340: 277-284. PMID 16051303 DOI: 10.1016/J.Virol.2005.06.034  0.281
2005 Pancera M, Lebowitz J, Schön A, Zhu P, Freire E, Kwong PD, Roux KH, Sodroski J, Wyatt R. Soluble mimetics of human immunodeficiency virus type 1 viral spikes produced by replacement of the native trimerization domain with a heterologous trimerization motif: characterization and ligand binding analysis. Journal of Virology. 79: 9954-69. PMID 16014956 DOI: 10.1128/Jvi.79.15.9954-9969.2005  0.279
2007 Dey B, Pancera M, Svehla K, Shu Y, Xiang SH, Vainshtein J, Li Y, Sodroski J, Kwong PD, Mascola JR, Wyatt R. Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity. Journal of Virology. 81: 5579-93. PMID 17360741 DOI: 10.1128/Jvi.02500-06  0.279
2019 Lei L, Tran K, Wang Y, Steinhardt JJ, Xiao Y, Chiang CI, Wyatt RT, Li Y. Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs. Frontiers in Microbiology. 10: 672. PMID 31065249 DOI: 10.3389/fmicb.2019.00672  0.278
2010 Pancera M, Majeed S, Ban YE, Chen L, Huang CC, Kong L, Kwon YD, Stuckey J, Zhou T, Robinson JE, Schief WR, Sodroski J, Wyatt R, Kwong PD. Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proceedings of the National Academy of Sciences of the United States of America. 107: 1166-71. PMID 20080564 DOI: 10.1073/Pnas.0911004107  0.278
2011 Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. Journal of Immunological Methods. 366: 8-19. PMID 21192942 DOI: 10.1016/J.Jim.2010.12.016  0.273
2008 Lam SN, Acharya P, Wyatt R, Kwong PD, Bewley CA. Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry. Bioorganic & Medicinal Chemistry. 16: 10113-20. PMID 18952441 DOI: 10.1016/J.Bmc.2008.10.005  0.272
2008 Karlsson Hedestam GB, Fouchier RA, Phogat S, Burton DR, Sodroski J, Wyatt RT. The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nature Reviews. Microbiology. 6: 143-55. PMID 18197170 DOI: 10.1038/Nrmicro1819  0.27
2012 Guenaga J, Wyatt RT. Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function. Plos Pathogens. 8: e1002806. PMID 22829767 DOI: 10.1371/journal.ppat.1002806  0.268
2011 McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Wyatt R, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696  0.267
1978 Wyatt R, Waschek J, Weinberger M, Sherman B. Effects of inhaled beclomethasone dipropionate and alternate-day prednisone on pituitary-adrenal function in children with chronic asthma. The New England Journal of Medicine. 299: 1387-92. PMID 362207 DOI: 10.1056/Nejm197812212992504  0.266
2008 Madani N, Schön A, Princiotto AM, Lalonde JM, Courter JR, Soeta T, Ng D, Wang L, Brower ET, Xiang SH, Kwon YD, Huang CC, Wyatt R, Kwong PD, Freire E, et al. Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120. Structure (London, England : 1993). 16: 1689-701. PMID 19000821 DOI: 10.1016/J.Str.2008.09.005  0.266
1978 Hendeles L, Weinberger M, Wyatt R. Guide to oral theophylline therapy for the treatment of chronic asthma. American Journal of Diseases of Children (1960). 132: 876-80. PMID 685905 DOI: 10.1001/Archpedi.1978.02120340052010  0.263
2010 Ofek G, Guenaga FJ, Schief WR, Skinner J, Baker D, Wyatt R, Kwong PD. Elicitation of structure-specific antibodies by epitope scaffolds Proceedings of the National Academy of Sciences of the United States of America. 107: 17880-17887. PMID 20876137 DOI: 10.1073/Pnas.1004728107  0.263
2010 Ofek G, McKee K, Yang Y, Yang ZY, Skinner J, Guenaga FJ, Wyatt R, Zwick MB, Nabel GJ, Mascola JR, Kwong PD. Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region. Journal of Virology. 84: 2955-62. PMID 20042512 DOI: 10.1128/Jvi.02257-09  0.257
1978 WYATT R, WASCHEK J, WEINBERGER M, SHERMAN B. 76. Adrenal suppression from alternate-day prednisone and inhaled beclomethasone Journal of Allergy and Clinical Immunology. 61: 151. DOI: 10.1016/0091-6749(78)90315-9  0.247
2007 Xie H, Ng D, Savinov SN, Dey B, Kwong PD, Wyatt R, Smith AB, Hendrickson WA. Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus Journal of Medicinal Chemistry. 50: 4898-4908. PMID 17803292 DOI: 10.1021/Jm070564E  0.246
2014 Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, ... ... Wyatt RT, et al. Proof of principle for epitope-focused vaccine design. Nature. 507: 201-6. PMID 24499818 DOI: 10.1038/Nature12966  0.24
2022 Damm D, Suleiman E, Theobald H, Wagner JT, Batzoni M, Ahlfeld Née Kohlhauser B, Walkenfort B, Albrecht JC, Ingale J, Yang L, Hasenberg M, Wyatt RT, Vorauer-Uhl K, Überla K, Temchura V. Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes. Pharmaceutics. 14. PMID 35890282 DOI: 10.3390/pharmaceutics14071385  0.238
2014 Sundling C, Zhang Z, Phad GE, Sheng Z, Wang Y, Mascola JR, Li Y, Wyatt RT, Shapiro L, Hedestam GBK. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization Journal of Immunology. 192: 3637-3644. PMID 24623130 DOI: 10.4049/Jimmunol.1303334  0.238
2023 Damm D, Suleiman E, Wagner JT, Klessing S, Pfister F, Elsayed H, Walkenfort B, Stobrawe J, Mayer J, Lehner E, Müller-Schmucker SM, Hasenberg M, Wyatt RT, Vorauer-Uhl K, Temchura V, et al. Modulation of immune responses to liposomal vaccines by intrastructural help. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 192: 112-125. PMID 37797679 DOI: 10.1016/j.ejpb.2023.10.003  0.237
2018 Yang L, Sharma SK, Cottrell C, Guenaga J, Tran K, Wilson R, Behrens AJ, Crispin M, de Val N, Wyatt RT. Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage. Frontiers in Immunology. 9: 1631. PMID 30065725 DOI: 10.3389/fimmu.2018.01631  0.234
2019 Khan SN, Sok D, Tran K, Movsesyan A, Dubrovskaya V, Burton DR, Wyatt RT. Correction for Khan et al., "Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry". Journal of Virology. 93. PMID 31092683 DOI: 10.1128/JVI.00391-19  0.228
2018 Singh R, Stoneham C, Lim C, Jia X, Guenaga J, Wyatt R, Wertheim JO, Xiong Y, Guatelli J. Phosphoserine acidic cluster motifs bind distinct basic regions on the µ subunits of clathrin adaptor protein complexes. The Journal of Biological Chemistry. PMID 30135209 DOI: 10.1074/Jbc.Ra118.003080  0.226
2020 Ols S, Yang L, Thompson EA, Pushparaj P, Tran K, Liang F, Lin A, Eriksson B, Karlsson Hedestam GB, Wyatt RT, Loré K. Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity. Cell Reports. 30: 3964-3971.e7. PMID 32209459 DOI: 10.1016/j.celrep.2020.02.111  0.224
2010 Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. Acs Chemical Biology. 5: 943-52. PMID 20681584 DOI: 10.1021/Cb100143M  0.223
2005 Dey AK, Khati M, Tang M, Wyatt R, Lea SM, James W. An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction. Journal of Virology. 79: 13806-10. PMID 16227301 DOI: 10.1128/Jvi.79.21.13806-13810.2005  0.211
2019 Morou A, Brunet-Ratnasingham E, Dubé M, Charlebois R, Mercier E, Darko S, Brassard N, Nganou-Makamdop K, Arumugam S, Gendron-Lepage G, Yang L, Niessl J, Baxter AE, Billingsley JM, Rajakumar PA, ... ... Wyatt RT, et al. Altered differentiation is central to HIV-specific CD4 T cell dysfunction in progressive disease. Nature Immunology. PMID 31308541 DOI: 10.1038/S41590-019-0418-X  0.202
2006 Navratilova I, Pancera M, Wyatt RT, Myszka DG. A biosensor-based approach toward purification and crystallization of G protein-coupled receptors. Analytical Biochemistry. 353: 278-83. PMID 16647033 DOI: 10.1016/j.ab.2006.03.049  0.2
2015 Ingale J, Tran K, Kong L, Dey B, McKee K, Schief W, Kwong PD, Mascola JR, Wyatt RT. Correction for Ingale et al., Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. Journal of Virology. 89: 6526. PMID 25979984 DOI: 10.1128/JVI.00596-15  0.197
1978 Wyatt R, Weinberger M, Hendeles L. Oral theophylline dosage for the management of chronic asthma. The Journal of Pediatrics. 92: 125-30. PMID 619054  0.17
2016 Mason RD, Welles HC, Adams C, Chakrabarti BK, Gorman J, Zhou T, Nguyen R, O'Dell S, Lusvarghi S, Bewley CA, Li H, Shaw GM, Sheng Z, Shapiro L, Wyatt R, et al. Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. Plos Pathogens. 12: e1005674. PMID 27219002 DOI: 10.1371/Journal.Ppat.1005674  0.16
2019 Landeras-Bueno S, Oda SI, Norris MJ, Li Salie Z, Guenaga J, Wyatt RT, Saphire EO. Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment. Mbio. 10. PMID 31337716 DOI: 10.1128/Mbio.00734-19  0.127
2024 Wyatt RC. Ether Inhalation in Convulsions. Western Journal of Medicine and Surgery. 1: 277-282. PMID 38209223  0.119
2002 Elkashef AM, Al-Barazi H, Venable D, Baker I, Hill J, Apud J, Wyatt RJ. Dopamine effect on the mitochondria potential in B lymphocytes of schizophrenic patients and normal controls. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 26: 145-8. PMID 11853105 DOI: 10.1016/S0278-5846(01)00239-1  0.087
2003 Apud JA, Egan MF, Wyatt RJ. Neuroleptic withdrawal in treatment-resistant patients with schizophrenia: tardive dyskinesia is not associated with supersensitive psychosis. Schizophrenia Research. 63: 151-60. PMID 12892869 DOI: 10.1016/S0920-9964(02)00338-9  0.078
2003 Chrapusta SJ, Egan MF, Wyatt RJ, Weinberger DR, Lipska BK. Neonatal ventral hippocampal damage modifies serum corticosterone and dopamine release responses to acute footshock in adult Sprague-Dawley rats. Synapse (New York, N.Y.). 47: 270-7. PMID 12539200 DOI: 10.1002/Syn.10179  0.071
2004 Brown AS, Begg MD, Gravenstein S, Schaefer CA, Wyatt RJ, Bresnahan M, Babulas VP, Susser ES. Serologic evidence of prenatal influenza in the etiology of schizophrenia. Archives of General Psychiatry. 61: 774-80. PMID 15289276 DOI: 10.1001/Archpsyc.61.8.774  0.069
2019 Richard MA, Sok P, Canon S, Brown AL, Peckham-Gregory EC, Nembhard WN, Carmichael SL, Ehli EA, Kallsen NA, Peyton SA, Davies GE, Patel A, Zamilpa I, Wyatt RA, Hobbs CA, et al. The role of genetic variation in DGKK on moderate and severe hypospadias. Birth Defects Research. PMID 31102501 DOI: 10.1002/Bdr2.1522  0.039
2002 Doudet DJ, Jivan S, Ruth TJ, Wyatt RJ. In vivo PET studies of the dopamine D1 receptors in rhesus monkeys with long-term MPTP-induced Parkinsonism. Synapse (New York, N.Y.). 44: 111-5. PMID 11891883 DOI: 10.1002/syn.10057  0.037
2003 Jones K, Colson PW, Holter MC, Lin S, Valencia E, Susser E, Wyatt RJ. Cost-effectiveness of critical time intervention to reduce homelessness among persons with mental illness. Psychiatric Services (Washington, D.C.). 54: 884-90. PMID 12773605 DOI: 10.1176/Appi.Ps.54.6.884  0.037
2021 Wyatt RA, James ST, Canon SJ, Patel AS, Zamilpa I. Hydronephrosis and Hydroureter Improvement Rates in Robotic-Assisted Laparoscopic Uretero-Ureterostomies: Does Anastomotic Site Matter? Urology. PMID 34186130 DOI: 10.1016/j.urology.2021.06.016  0.036
2006 Herrell R, Henter ID, Mojtabai R, Bartko JJ, Venable D, Susser E, Merikangas KR, Wyatt RJ. First psychiatric hospitalizations in the US military: the National Collaborative Study of Early Psychosis and Suicide (NCSEPS). Psychological Medicine. 36: 1405-15. PMID 16879759 DOI: 10.1017/S0033291706008348  0.033
2005 El-Mallakh RS, Garver D, Holcomb JA, Wyatt RJ. Post lumbar-puncture headaches in schizophrenic and psychiatrically normal control subjects. Schizophrenia Research. 77: 111-2. PMID 16005392 DOI: 10.1016/j.schres.2005.02.017  0.032
2005 Fernandez MI, Martin-Ucar AE, Lee HD, West KJ, Wyatt R, Waller DA. Does a thoracic epidural confer any additional benefit following video-assisted thoracoscopic pleurectomy for primary spontaneous pneumothorax? European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 27: 671-4. PMID 15784372 DOI: 10.1016/j.ejcts.2004.12.045  0.031
2002 Brown AS, Schaefer CA, Wyatt RJ, Begg MD, Goetz R, Bresnahan MA, Harkavy-Friedman J, Gorman JM, Malaspina D, Susser ES. Paternal age and risk of schizophrenia in adult offspring. The American Journal of Psychiatry. 159: 1528-33. PMID 12202273 DOI: 10.1176/Appi.Ajp.159.9.1528  0.031
2006 Ahmed-Nusrath A, Annamanneni R, Wyatt R, Leverment J. Management of major hemorrhage during mediastinoscopy. Journal of Cardiothoracic and Vascular Anesthesia. 20: 762-3; author reply . PMID 17023309 DOI: 10.1053/j.jvca.2006.03.016  0.023
2003 Mojtabai R, Rosenheck RA, Wyatt RJ, Susser ES. Use of VA aftercare following military discharge among patients with serious mental disorders. Psychiatric Services (Washington, D.C.). 54: 383-8. PMID 12610248 DOI: 10.1176/Appi.Ps.54.3.383  0.02
2016 Ognibene FP, Gallin JI, Baum BJ, Wyatt RG, Gottesman MM. Outcomes From the NIH Clinical Research Training Program: A Mentored Research Experience to Enhance Career Development of Clinician-Scientists. Academic Medicine : Journal of the Association of American Medical Colleges. PMID 27224296 DOI: 10.1097/Acm.0000000000001245  0.015
2010 Garcia-Perez A, Wyatt RG, Gottesman MM. Changes in NIH criteria for tenure to reward clinical/translational teams. Clinical and Translational Science. 3: 4-5. PMID 20443943 DOI: 10.1111/j.1752-8062.2009.00164.x  0.01
2008 Nokes SR, Pierce WB, Wyatt RA, Smith TM. MR imaging in the diagnosis of a ruptured cornual pregnancy. The Journal of the Arkansas Medical Society. 105: 87-8. PMID 18982902  0.01
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