John D. Elsworth - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Dopamine Dysfunction

159 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jamwal S, Blackburn JK, Elsworth JD. Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brain. Biology of Sex Differences. 14: 65. PMID 37770961 DOI: 10.1186/s13293-023-00551-6  0.783
2022 Jamwal S, Blackburn JK, Elsworth JD. Expression of PON2 isoforms varies among brain regions in male and female African green monkeys. Free Radical Biology & Medicine. 178: 215-218. PMID 34890766 DOI: 10.1016/j.freeradbiomed.2021.12.005  0.791
2021 Blackburn JK, Jamwal S, Wang W, Elsworth JD. Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disorders. Neurochemistry International. 152: 105222. PMID 34767873 DOI: 10.1016/j.neuint.2021.105222  0.802
2021 Jamwal S, Blackburn JK, Elsworth JD. Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeys. Free Radical Biology & Medicine. PMID 33722626 DOI: 10.1016/j.freeradbiomed.2021.03.003  0.792
2020 Jamwal S, Blackburn J, Elsworth JD. PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders. Pharmacology & Therapeutics. 107705. PMID 33039420 DOI: 10.1016/j.pharmthera.2020.107705  0.776
2020 Jamwal S, Elsworth JD, Rahi V, Kumar P. Gene Therapy and immunotherapy as promising strategies to combat Huntington's Disease associated neurodegeneration: Emphasis on recent updates and future perspectives. Expert Review of Neurotherapeutics. PMID 32720531 DOI: 10.1080/14737175.2020.1801424  0.657
2020 Chung YG, Seay M, Elsworth J, Redmond DE. Generation of pluripotent stem cells using somatic cell nuclear transfer and induced pluripotent somatic cells from African Green Monkeys. Stem Cells and Development. PMID 32715987 DOI: 10.1089/Scd.2020.0059  0.345
2020 Jamwal S, Gautam A, Elsworth J, Kumar M, Chawla R, Kumar P. An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic. Life Sciences. 118105. PMID 32687917 DOI: 10.1016/J.Lfs.2020.118105  0.672
2020 Elsworth JD. Parkinson's disease treatment: past, present, and future. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 32172471 DOI: 10.1007/S00702-020-02167-1  0.308
2020 Blackburn JK, Curry DW, Thomsen AN, Roth RH, Elsworth JD. Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism. Experimental Neurology. 113234. PMID 32044330 DOI: 10.1016/J.Expneurol.2020.113234  0.772
2019 Stutz B, Nasrallah C, Nigro M, Curry D, Liu ZW, Gao XB, Elsworth JD, Mintz L, Horvath TL. Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity. Molecular Metabolism. PMID 30833218 DOI: 10.1016/J.Molmet.2019.02.005  0.812
2018 Curry DW, Stutz B, Andrews ZB, Elsworth JD. Targeting AMPK Signaling as a Neuroprotective Strategy in Parkinson's Disease. Journal of Parkinson's Disease. PMID 29614701 DOI: 10.3233/Jpd-171296  0.782
2017 Sousa AMM, Zhu Y, Raghanti MA, Kitchen RR, Onorati M, Tebbenkamp ATN, Stutz B, Meyer KA, Li M, Kawasawa YI, Liu F, Perez RG, Mele M, Carvalho T, Skarica M, ... ... Elsworth JD, et al. Molecular and cellular reorganization of neural circuits in the human lineage. Science (New York, N.Y.). 358: 1027-1032. PMID 29170230 DOI: 10.1126/Science.Aan3456  0.344
2017 Golub MS, Hackett EP, Hogrefe CE, Leranth C, Elsworth JD, Roth RH. Cognitive performance of juvenile monkeys after chronic fluoxetine treatment. Developmental Cognitive Neuroscience. 26: 52-61. PMID 28521247 DOI: 10.1016/J.Dcn.2017.04.008  0.58
2016 Bayliss JA, Lemus MB, Santos VV, Deo M, Davies JS, Kemp BE, Elsworth JD, Andrews ZB. Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons. Plos One. 11: e0159381. PMID 27467571 DOI: 10.1371/Journal.Pone.0159381  0.458
2016 Gonzalez R, Garitaonandia I, Poustovoitov M, Abramihina T, McEntire C, Culp B, Attwood J, Noskov A, Christiansen-Weber T, Khater M, Mora-Castilla S, To C, Crain A, Sherman G, Semechkin A, ... ... Elsworth JD, et al. Neural Stem Cells Derived from Human Parthenogenetic Stem Cells Engraft and Promote Recovery in a Nonhuman Primate Model of Parkinson's Disease. Cell Transplantation. PMID 27213850 DOI: 10.3727/096368916X691682  0.402
2016 Garrick JM, Dao K, de Laat R, Elsworth J, Cole TB, Marsillach J, Furlong CE, Costa LG. Developmental expression of paraoxonase 2. Chemico-Biological Interactions. PMID 27062895 DOI: 10.1016/J.Cbi.2016.04.001  0.323
2016 Bayliss JA, Lemus MB, Stark R, Santos VV, Thompson A, Rees DJ, Galic S, Elsworth JD, Kemp BE, Davies JS, Andrews ZB. Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3049-63. PMID 26961958 DOI: 10.1523/Jneurosci.4373-15.2016  0.435
2016 Bayliss JA, Lemus M, Santos VV, Deo M, Elsworth J, Andrews ZB. Acylated but not des-acyl ghrelin is neuroprotective in an MPTP mouse model of Parkinson's Disease. Journal of Neurochemistry. PMID 26872221 DOI: 10.1111/Jnc.13576  0.364
2015 Gonzalez R, Garitaonandia I, Crain A, Poustovoitov M, Abramihina T, Noskov A, Jiang C, Morey R, Laurent LC, Elsworth JD, Snyder EY, Redmond DE, Semechkin R. Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease. Cell Transplantation. 24: 681-90. PMID 25839189 DOI: 10.3727/096368915X687769  0.341
2015 Bubak AN, Redmond DE, Elsworth JD, Roth RH, Collier TJ, Bjugstad KB, Blanchard BC, Sladek JR. A potential compensatory role for endogenous striatal tyrosine hydroxylase-positive neurons in a nonhuman primate model of Parkinson's disease. Cell Transplantation. 24: 673-80. PMID 25839107 DOI: 10.3727/096368915X687741  0.677
2015 Elsworth JD, Jentsch JD, Groman SM, Roth RH, Redmond ED, Leranth C. Low circulating levels of bisphenol-A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys. The Journal of Comparative Neurology. 523: 1248-57. PMID 25557059 DOI: 10.1002/Cne.23735  0.613
2015 Elsworth JD, Groman SM, Jentsch JD, Leranth C, Redmond DE, Kim JD, Diano S, Roth RH. Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522392 DOI: 10.1093/ijnp/pyu048  0.599
2015 Wolff EF, Mutlu L, Massasa EE, Elsworth JD, Eugene Redmond D, Taylor HS. Endometrial stem cell transplantation in MPTP- exposed primates: an alternative cell source for treatment of Parkinson's disease. Journal of Cellular and Molecular Medicine. 19: 249-56. PMID 25283241 DOI: 10.1111/Jcmm.12433  0.351
2014 Groman SM, James AS, Seu E, Tran S, Clark TA, Harpster SN, Crawford M, Burtner JL, Feiler K, Roth RH, Elsworth JD, London ED, Jentsch JD. In the blink of an eye: relating positive-feedback sensitivity to striatal dopamine D2-like receptors through blink rate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14443-54. PMID 25339755 DOI: 10.1523/Jneurosci.3037-14.2014  0.628
2014 Wakeman DR, Weiss S, Sladek JR, Elsworth JD, Bauereis B, Leranth C, Hurley PJ, Roth RH, Redmond DE. Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates. Cell Transplantation. 23: 981-94. PMID 23562290 DOI: 10.3727/096368913X664865  0.668
2013 Elsworth JD, Roth RH. Pregnancy, a risky time: keep calm, clean, and carry on! Biological Psychiatry. 74: 478-9. PMID 24034364 DOI: 10.1016/J.Biopsych.2013.07.027  0.52
2013 Redmond DE, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR. Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2160-8. PMID 23913185 DOI: 10.1038/Mt.2013.180  0.667
2013 Elsworth JD, Redmond DE, Roth RH. Coordinated expression of dopamine transporter and vesicular monoamine transporter in the primate striatum during development. Synapse (New York, N.Y.). 67: 580-5. PMID 23468413 DOI: 10.1002/Syn.21662  0.697
2013 Elsworth JD, Jentsch JD, Vandevoort CA, Roth RH, Jr DE, Leranth C. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. Neurotoxicology. 35: 113-20. PMID 23337607 DOI: 10.1016/J.Neuro.2013.01.001  0.677
2013 Elsworth JD, Leranth C, Redmond DE, Roth RH. Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 905-12. PMID 22947206 DOI: 10.1017/S1461145712000892  0.658
2012 Morrow BA, Roth RH, Redmond DE, Diano S, Elsworth JD. Susceptibility to a parkinsonian toxin varies during primate development. Experimental Neurology. 235: 273-81. PMID 22366325 DOI: 10.1016/J.Expneurol.2012.02.005  0.687
2012 Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleiman RJ, Wahlestedt C. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proceedings of the National Academy of Sciences of the United States of America. 109: 3125-30. PMID 22315408 DOI: 10.1073/Pnas.1113793109  0.567
2012 Elsworth JD, Groman SM, Jentsch JD, Valles R, Shahid M, Wong E, Marston H, Roth RH. Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration. Neuropharmacology. 62: 1442-52. PMID 21875607 DOI: 10.1016/J.Neuropharm.2011.08.026  0.677
2011 Elsworth JD, Hajszan T, Leranth C, Roth RH. Loss of asymmetric spine synapses in dorsolateral prefrontal cortex of cognitively impaired phencyclidine-treated monkeys. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1411-5. PMID 21733230 DOI: 10.1017/S1461145711000939  0.584
2011 Abizaid A, Mineur YS, Roth RH, Elsworth JD, Sleeman MW, Picciotto MR, Horvath TL. Reduced locomotor responses to cocaine in ghrelin-deficient mice. Neuroscience. 192: 500-6. PMID 21699961 DOI: 10.1016/J.Neuroscience.2011.06.001  0.654
2011 Elsworth JD, Morrow BA, Hajszan T, Leranth C, Roth RH. Phencyclidine-induced loss of asymmetric spine synapses in rodent prefrontal cortex is reversed by acute and chronic treatment with olanzapine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2054-61. PMID 21677652 DOI: 10.1038/Npp.2011.96  0.592
2011 Morrow BA, Roth RH, Redmond DE, Elsworth JD. Impact of methamphetamine on dopamine neurons in primates is dependent on age: implications for development of Parkinson's disease. Neuroscience. 189: 277-85. PMID 21640165 DOI: 10.1016/J.Neuroscience.2011.05.046  0.701
2011 Hurley PJ, Elsworth JD, Whittaker MC, Roth RH, Redmond DE. Aged monkeys as a partial model for Parkinson's disease. Pharmacology, Biochemistry, and Behavior. 99: 324-32. PMID 21620883 DOI: 10.1016/J.Pbb.2011.05.007  0.657
2011 Horvath TL, Erion DM, Elsworth JD, Roth RH, Shulman GI, Andrews ZB. GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function. Neurobiology of Disease. 43: 152-62. PMID 21406233 DOI: 10.1016/J.Nbd.2011.03.005  0.619
2011 Wolff EF, Gao XB, Yao KV, Andrews ZB, Du H, Elsworth JD, Taylor HS. Endometrial stem cell transplantation restores dopamine production in a Parkinson's disease model. Journal of Cellular and Molecular Medicine. 15: 747-55. PMID 20406327 DOI: 10.1111/J.1582-4934.2010.01068.X  0.423
2010 Redmond DE, Weiss S, Elsworth JD, Roth RH, Wakeman DR, Bjugstad KB, Collier TJ, Blanchard BC, Teng YD, Synder EY, Sladek JR. Cellular repair in the parkinsonian nonhuman primate brain. Rejuvenation Research. 13: 188-94. PMID 20370501 DOI: 10.1089/Rej.2009.0960  0.677
2010 Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 588-93. PMID 20010918 DOI: 10.1038/Mt.2009.286  0.606
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/Jneurosci.3890-09.2009  0.693
2009 Redmond DE, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR. Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF. The Journal of Comparative Neurology. 515: 31-40. PMID 19399891 DOI: 10.1002/Cne.22028  0.65
2008 Jentsch JD, Sanchez D, Elsworth JD, Roth RH. Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype. Brain Research. 1246: 41-6. PMID 18977208 DOI: 10.1016/J.Brainres.2008.10.006  0.641
2008 Sladek JR, Bjugstad KB, Collier TJ, Bundock EA, Blanchard BC, Elsworth JD, Roth RH, Redmond DE. Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate. Cell Transplantation. 17: 427-44. PMID 18522245 DOI: 10.3727/096368908784423274  0.657
2008 Bjugstad KB, Teng YD, Redmond DE, Elsworth JD, Roth RH, Cornelius SK, Snyder EY, Sladek JR. Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease. Experimental Neurology. 211: 362-9. PMID 18394605 DOI: 10.1016/J.Expneurol.2008.01.025  0.637
2008 Elsworth JD, Redmond DE, Leranth C, Bjugstad KB, Sladek JR, Collier TJ, Foti SB, Samulski RJ, Vives KP, Roth RH. AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons. Experimental Neurology. 211: 252-8. PMID 18346734 DOI: 10.1016/J.Expneurol.2008.01.026  0.698
2008 Elsworth JD, Jentsch JD, Morrow BA, Redmond DE, Roth RH. Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 491-6. PMID 17507917 DOI: 10.1038/Sj.Npp.1301448  0.656
2008 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Corrigendum to "prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors". [Neuroscience 147 (2007) 419-427] (DOI:10.1016/j.neuroscience.2007.04.036) Neuroscience. 156: 800. DOI: 10.1016/J.Neuroscience.2008.08.024  0.716
2007 Morrow BA, Hajszan T, Leranth C, Elsworth JD, Roth RH. Prenatal exposure to cocaine is associated with increased number of spine synapses in rat prelimbic cortex. Synapse (New York, N.Y.). 61: 862-5. PMID 17630673 DOI: 10.1002/Syn.20430  0.622
2007 Redmond DE, Bjugstad KB, Teng YD, Ourednik V, Ourednik J, Wakeman DR, Parsons XH, Gonzalez R, Blanchard BC, Kim SU, Gu Z, Lipton SA, Markakis EA, Roth RH, Elsworth JD, et al. Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 12175-80. PMID 17586681 DOI: 10.1073/Pnas.0704091104  0.672
2007 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: role of autoreceptors. Neuroscience. 147: 419-27. PMID 17543464 DOI: 10.1016/J.Neuroscience.2007.04.036  0.731
2007 Morrow BA, Roth RH, Redmond DE, Sladek JR, Elsworth JD. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. Experimental Neurology. 204: 802-7. PMID 17313945 DOI: 10.1016/J.Expneurol.2007.01.009  0.686
2007 Morrow BA, Elsworth JD, Roth RH. Repeated phencyclidine in monkeys results in loss of parvalbumin-containing axo-axonic projections in the prefrontal cortex. Psychopharmacology. 192: 283-90. PMID 17265073 DOI: 10.1007/S00213-007-0708-0  0.607
2006 Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal of Clinical Investigation. 116: 3229-39. PMID 17060947 DOI: 10.1172/Jci29867  0.665
2006 Andrews ZB, Rivera A, Elsworth JD, Roth RH, Agnati L, Gago B, Abizaid A, Schwartz M, Fuxe K, Horvath TL. Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function. The European Journal of Neuroscience. 24: 32-6. PMID 16882005 DOI: 10.1111/J.1460-9568.2006.04906.X  0.69
2005 Ariano MA, Grissell AE, Littlejohn FC, Buchanan TM, Elsworth JD, Collier TJ, Steece-Collier K. Partial dopamine loss enhances activated caspase-3 activity: differential outcomes in striatal projection systems. Journal of Neuroscience Research. 82: 387-96. PMID 16180225 DOI: 10.1002/Jnr.20644  0.455
2005 Bjugstad KB, Redmond DE, Teng YD, Elsworth JD, Roth RH, Blanchard BC, Snyder EY, Sladek JR. Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures. Cell Transplantation. 14: 183-92. PMID 15929553 DOI: 10.3727/000000005783983098  0.662
2005 Morrow BA, Redmond DE, Roth RH, Elsworth JD. Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey. The Journal of Comparative Neurology. 488: 215-23. PMID 15924344 DOI: 10.1002/Cne.20599  0.67
2005 Morrow BA, Elsworth JD, Roth RH. Prenatal exposure to cocaine selectively disrupts the development of parvalbumin containing local circuit neurons in the medial prefrontal cortex of the rat. Synapse (New York, N.Y.). 56: 1-11. PMID 15700288 DOI: 10.1002/Syn.20121  0.635
2005 Andrews ZB, Horvath B, Barnstable CJ, Elsworth J, Elseworth J, Yang L, Beal MF, Roth RH, Matthews RT, Horvath TL. Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 184-91. PMID 15634780 DOI: 10.1523/Jneurosci.4269-04.2005  0.641
2003 Morrow BA, Elsworth JD, Roth RH. Axo-axonic structures in the medial prefrontal cortex of the rat: reduction by prenatal exposure to cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5227-34. PMID 12832547 DOI: 10.1523/Jneurosci.23-12-05227.2003  0.62
2003 Horvath TL, Diano S, Leranth C, Garcia-Segura LM, Cowley MA, Shanabrough M, Elsworth JD, Sotonyi P, Roth RH, Dietrich EH, Matthews RT, Barnstable CJ, Redmond DE. Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease. Endocrinology. 144: 2757-60. PMID 12810526 DOI: 10.1210/En.2003-0163  0.667
2002 Morrow BA, Elsworth JD, Roth RH. Fear-like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment. Synapse (New York, N.Y.). 46: 11-8. PMID 12211094 DOI: 10.1002/Syn.10109  0.617
2002 Redmond AJ, Morrow BA, Elsworth JD, Roth RH. Selective activation of the A10, but not A9, dopamine neurons in the rat by the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline. Neuroscience Letters. 328: 209-12. PMID 12147308 DOI: 10.1016/S0304-3940(02)00566-9  0.635
2002 Morrow BA, Elsworth JD, Roth RH. Male rats exposed to cocaine in utero demonstrate elevated expression of Fos in the prefrontal cortex in response to environment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 275-85. PMID 11850142 DOI: 10.1016/S0893-133X(01)00359-1  0.637
2002 Morrow BA, Elsworth JD, Roth RH. Prenatal cocaine exposure disrupts non-spatial, short-term memory in adolescent and adult male rats. Behavioural Brain Research. 129: 217-23. PMID 11809514 DOI: 10.1016/S0166-4328(01)00338-2  0.604
2002 Collier TJ, Sortwell CE, Elsworth JD, Taylor JR, Roth RH, Sladek JR, Redmond DE. Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease. The Journal of Comparative Neurology. 442: 320-30. PMID 11793337 DOI: 10.1002/Cne.10108  0.671
2001 Elsworth JD, Morrow BA, Roth RH. Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. Synapse (New York, N.Y.). 42: 80-3. PMID 11574943 DOI: 10.1002/Syn.1102  0.675
2001 Morrow BA, Elsworth JD, Roth RH. Prenatal exposure to cocaine reduces the number and enhances reactivity of A10 dopaminergic neurons to environmental stress. Synapse (New York, N.Y.). 41: 337-44. PMID 11494404 DOI: 10.1002/Syn.1090  0.661
2001 Connor B, Kozlowski DA, Unnerstall JR, Elsworth JD, Tillerson JL, Schallert T, Bohn MC. Glial cell line-derived neurotrophic factor (GDNF) gene delivery protects dopaminergic terminals from degeneration. Experimental Neurology. 169: 83-95. PMID 11312561 DOI: 10.1006/Exnr.2001.7638  0.427
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  0.625
2000 Leranth C, Roth RH, Elsworth JD, Naftolin F, Horvath TL, Redmond DE. Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8604-9. PMID 11102464 DOI: 10.1523/Jneurosci.20-23-08604.2000  0.676
2000 Morrow BA, Roth RH, Elsworth JD. TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat. Brain Research Bulletin. 52: 519-23. PMID 10974491 DOI: 10.1016/S0361-9230(00)00290-2  0.62
2000 Morrow BA, Redmond AJ, Roth RH, Elsworth JD. The predator odor, TMT, displays a unique, stress-like pattern of dopaminergic and endocrinological activation in the rat. Brain Research. 864: 146-51. PMID 10793199 DOI: 10.1016/S0006-8993(00)02174-0  0.616
2000 Morrow BA, Elsworth JD, Lee EJ, Roth RH. Divergent effects of putative anxiolytics on stress-induced fos expression in the mesoprefrontal system of the rat. Synapse (New York, N.Y.). 36: 143-54. PMID 10767061 DOI: 10.1002/(Sici)1098-2396(200005)36:2<143::Aid-Syn7>3.0.Co;2-H  0.637
2000 Elsworth JD, Taylor JR, Sladek JR, Collier TJ, Redmond DE, Roth RH. Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment. Neuroscience. 95: 399-408. PMID 10658619 DOI: 10.1016/S0306-4522(99)00437-6  0.695
1999 Taylor JR, Elsworth JD, Lawrence MS, Sladek JR, Roth RH, Redmond DE. Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys. Experimental Neurology. 158: 214-20. PMID 10448434 DOI: 10.1006/Exnr.1999.7093  0.652
1999 Morrow BA, Elsworth JD, Rasmusson AM, Roth RH. The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat. Neuroscience. 92: 553-64. PMID 10408604 DOI: 10.1016/S0306-4522(99)00014-7  0.664
1999 Morrow BA, Elsworth JD, Inglis FM, Roth RH. An antisense oligonucleotide reverses the footshock-induced expression of fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5666-73. PMID 10377372 DOI: 10.1523/Jneurosci.19-13-05666.1999  0.595
1999 Morrow BA, Elsworth JD, Zito C, Roth RH. Biochemical and behavioral anxiolytic-like effects of R(+)HA-966 at the level of the ventral tegmental area in rats. Psychopharmacology. 143: 227-34. PMID 10353424 DOI: 10.1007/S002130050941  0.633
1999 Jentsch JD, Taylor JR, Elsworth JD, Redmond DE, Roth RH. Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits. Neuroscience. 90: 823-32. PMID 10218783 DOI: 10.1016/S0306-4522(98)00481-3  0.653
1999 Jentsch JD, Taylor JR, Redmond DE, Elsworth JD, Youngren KD, Roth RH. Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology. 142: 78-84. PMID 10102786 DOI: 10.1007/S002130050865  0.632
1998 During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/Sj.Gt.3300650  0.756
1998 Taylor JR, Punch LJ, Elsworth JD. A comparison of the effects of clonidine and CNQX infusion into the locus coeruleus and the amygdala on naloxone-precipitated opiate withdrawal in the rat. Psychopharmacology. 138: 133-42. PMID 9718282 DOI: 10.1007/S002130050655  0.334
1998 Elsworth JD, Brittan MS, Taylor JR, Sladek JR, Redmond DE, Innis RB, Zea-Ponce Y, Roth RH. Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study. Brain Research. 795: 55-62. PMID 9622593 DOI: 10.1016/S0006-8993(98)00252-2  0.695
1998 Sortwell CE, Blanchard BC, Collier TJ, Elsworth JD, Taylor JR, Roth RH, Redmond DE, Sladek JR. Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model. Brain Research. 791: 117-24. PMID 9593853 DOI: 10.1016/S0006-8993(98)00086-9  0.616
1998 Sladek JR, Collier TJ, Elsworth JD, Roth RH, Taylor JR, Redmond DE. Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates. Cell Transplantation. 7: 87-96. PMID 9588591 DOI: 10.1016/S0963-6897(98)00007-4  0.655
1998 Jentsch JD, Elsworth JD, Taylor JR, Redmond DE, Roth RH. Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia. Advances in Pharmacology (San Diego, Calif.). 42: 810-4. PMID 9328021 DOI: 10.1016/S1054-3589(08)60870-4  0.622
1997 Morrow BA, Lee EJ, Taylor JR, Elsworth JD, Nye HE, Roth RH. (S)-(-)-HA-966, a gamma-hydroxybutyrate-like agent, prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear and cocaine sensitization. The Journal of Pharmacology and Experimental Therapeutics. 283: 712-21. PMID 9353390  0.62
1997 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Redmond DE. Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus). Neuroscience. 81: 745-55. PMID 9316026 DOI: 10.1016/S0306-4522(97)00214-5  0.636
1997 Jentsch JD, Redmond DE, Elsworth JD, Taylor JR, Youngren KD, Roth RH. Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. Science (New York, N.Y.). 277: 953-5. PMID 9252326 DOI: 10.1126/Science.277.5328.953  0.665
1997 Collier TJ, Redmond DE, Roth RH, Elsworth JD, Taylor JR, Sladek JR. Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry. Cell Transplantation. 6: 135-40. PMID 9142445 DOI: 10.1016/S0963-6897(97)00003-1  0.648
1997 Elsworth JD, Roth RH. Dopamine synthesis, uptake, metabolism, and receptors: relevance to gene therapy of Parkinson's disease. Experimental Neurology. 144: 4-9. PMID 9126143 DOI: 10.1006/Exnr.1996.6379  0.664
1997 Jentsch JD, Elsworth JD, Redmond DE, Roth RH. Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1769-75. PMID 9030635 DOI: 10.1523/Jneurosci.17-05-01769.1997  0.676
1997 Tam SY, Elsworth JD, Sladek JR, Redmond DE, Roth RH. Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys. Experimental Neurology. 143: 172-6. PMID 9000456 DOI: 10.1006/Exnr.1996.6338  0.594
1996 Horger BA, Taylor JR, Elsworth JD, Jatlow PI, Roth RH. Sensitization to the locomotor activating effects of cocaine following cocaethylene-preexposure. Brain Research. 733: 133-7. PMID 8891259 DOI: 10.1016/0006-8993(96)00783-4  0.62
1996 Jatlow P, McCance EF, Bradberry CW, Elsworth JD, Taylor JR, Roth RH. Alcohol plus cocaine: the whole is more than the sum of its parts. Therapeutic Drug Monitoring. 18: 460-4. PMID 8857569 DOI: 10.1097/00007691-199608000-00026  0.741
1996 Deutch AY, Lewis DA, Whitehead RE, Elsworth JD, Iadarola MJ, Redmond DE, Roth RH. Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate. Synapse (New York, N.Y.). 23: 182-91. PMID 8807746 DOI: 10.1002/(Sici)1098-2396(199607)23:3<182::Aid-Syn7>3.0.Co;2-4  0.746
1996 Morrow BA, Elsworth JD, Roth RH. Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning. Synapse (New York, N.Y.). 22: 100-5. PMID 8787125 DOI: 10.1002/(Sici)1098-2396(199602)22:2<100::Aid-Syn2>3.0.Co;2-H  0.676
1996 Horger BA, Elsworth JD, Roth RH. Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966. Journal of Neurochemistry. 66: 1959-62. PMID 8780023 DOI: 10.1046/J.1471-4159.1996.66051959.X  0.676
1996 Elsworth JD, Sladek JR, Taylor JR, Collier TJ, Redmond DE, Roth RH. Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys. Neuroscience. 72: 477-84. PMID 8737417 DOI: 10.1016/0306-4522(95)00564-1  0.682
1996 Elsworth JD, Brittan MS, Taylor JR, Sladek JR, al-Tikriti MS, Zea-Ponce Y, Innis RB, Redmond DE, Roth RH. Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys. Cell Transplantation. 5: 315-25. PMID 8689042 DOI: 10.1016/0963-6897(95)02034-9  0.696
1995 Taylor JR, Elsworth JD, Sladek JR, Collier TJ, Roth RH, Redmond DE. Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys. Cell Transplantation. 4: 13-26. PMID 7728327 DOI: 10.1016/0963-6897(94)00035-I  0.69
1995 Horger BA, Elsworth JD, Roth RH. Selective increase in dopamine utilization in the shell subdivision of the nucleus accumbens by the benzodiazepine inverse agonist FG 7142. Journal of Neurochemistry. 65: 770-4. PMID 7616234 DOI: 10.1046/J.1471-4159.1995.65020770.X  0.681
1994 Elsworth JD, al-Tikriti MS, Sladek JR, Taylor JR, Innis RB, Redmond DE, Roth RH. Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function. Experimental Neurology. 126: 300-4. PMID 7925828 DOI: 10.1006/Exnr.1994.1068  0.672
1994 Horger BA, Taylor JR, Elsworth JD, Roth RH. Preexposure to, but not cotreatment with, the neurotensin antagonist SR 48692 delays the development of cocaine sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 11: 215-22. PMID 7865101 DOI: 10.1038/Sj.Npp.1380108  0.608
1994 Collier TJ, Elsworth JD, Taylor JR, Sladek JR, Roth RH, Redmond DE. Peripheral nerve-dopamine neuron co-grafts in MPTP-treated monkeys: augmentation of tyrosine hydroxylase-positive fiber staining and dopamine content in host systems. Neuroscience. 61: 875-89. PMID 7838385 DOI: 10.1016/0306-4522(94)90410-3  0.641
1994 Tam S, Elsworth JD, Redmond DE, Roth RH. Expression Of A Novel TRK C Receptor Isoform With Truncated Extracellular Domain In Fetal And Adult Monkey Brains Neuropsychopharmacology. 11: 286-286. DOI: 10.1038/Sj.Npp.1380219  0.585
1993 Bradberry CW, Nobiletti JB, Elsworth JD, Murphy B, Jatlow P, Roth RH. Cocaine and cocaethylene: microdialysis comparison of brain drug levels and effects on dopamine and serotonin. Journal of Neurochemistry. 60: 1429-35. PMID 8455033 DOI: 10.1111/J.1471-4159.1993.Tb03305.X  0.765
1993 Elsworth JD, Taylor JR, Berger P, Roth RH. Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum. Neurochemistry International. 23: 61-9. PMID 8369733 DOI: 10.1016/0197-0186(93)90144-T  0.674
1993 Sladek JR, Collier TJ, Elsworth JD, Taylor JR, Roth RH, Redmond DE. Can graft-derived neurotrophic activity be used to direct axonal outgrowth of grafted dopamine neurons for circuit reconstruction in primates? Experimental Neurology. 124: 134-9. PMID 8282070 DOI: 10.1006/exnr.1993.1184  0.589
1993 Redmond DE, Roth RH, Spencer DD, Naftolin F, Leranth C, Robbins RJ, Marek KL, Elsworth JD, Taylor JR, Sass KJ. Neural transplantation for neurodegenerative diseases: past, present, and future. Annals of the New York Academy of Sciences. 695: 258-66. PMID 8239293 DOI: 10.1111/J.1749-6632.1993.Tb23064.X  0.677
1993 Sladek JR, Elsworth JD, Roth RH, Evans LE, Collier TJ, Cooper SJ, Taylor JR, Redmond DE. Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates. Experimental Neurology. 122: 16-27. PMID 8101820 DOI: 10.1006/exnr.1993.1103  0.642
1993 Elsworth JD, Taylor JR, Jatlow P, Roth RH. Serotonin involvement in cocaine sensitization: Clues from studies with cocaine analogs Drug Development Research. 30: 189-200. DOI: 10.1002/Ddr.430300311  0.633
1993 Spencer DD, Robbins RJ, Naftolin F, Marek KL, Vollmer T, Leranth C, Roth RH, Price LH, Gjedde A, Bunney BS, Sass KJ, Elsworth JD, Kier EL, Makuch R, Hoffer PB, et al. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with parkinson’s disease Obstetrical and Gynecological Survey. 48: 413-415.  0.556
1993 Elsworth JD, Roth RH. Deprenyl: Pharmacological aspects of its clinical effects Biogenic Amines. 9: 381-394.  0.5
1992 Innis RB, Malison RT, Al-Tikriti M, Hoffer PB, Sybirska EH, Seibyl JP, Zoghbi SS, Baldwin RM, Laruelle M, Smith EO, Charney DS, Heninger G, Elsworth JD, Roth RH. Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates Synapse. 10: 177-184. PMID 1532675 DOI: 10.1002/Syn.890100302  0.651
1992 Fetting JH, Stefanek ME, Sheidler VR, Elsworth JD, Piantadosi S, Roth RH. Noradrenergic activity in anticipatory nausea. Psychosomatic Medicine. 54: 641-7. PMID 1333617 DOI: 10.1097/00006842-199211000-00003  0.523
1992 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Collier TJ, Redmond DE. Quantitative behavioral assessment methods for the analysis of graft-induced motor and cognitive function in the MPTP-treated Parkinsonian monkey Journal of Neural Transplantation and Plasticity. 3: 227-228. DOI: 10.1155/Np.1992.227  0.622
1992 Elsworth JD, Sladek JR, Redmond DE, Taylor JR, Collier RJ, Roth RH. Biochemical changes induced by emblyonic substantia nigra transplanted to the striatum of Parkinsonian monkeys Journal of Neural Transplantation and Plasticity. 3: 216-217. DOI: 10.1155/Np.1992.216  0.619
1991 Taylor JR, Lewis VO, Elsworth JD, Pivirotto P, Roth RH, Redmond DE. Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats. Psychopharmacology. 103: 407-14. PMID 2057541 DOI: 10.1007/Bf02244297  0.571
1991 Jatlow P, Elsworth JD, Bradberry CW, Winger G, Taylor JR, Russell R, Roth RH. Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life Sciences. 48: 1787-94. PMID 2020260 DOI: 10.1016/0024-3205(91)90217-Y  0.759
1991 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Collier TJ, Redmond DE. Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls. Experimental Brain Research. 85: 335-48. PMID 1893983 DOI: 10.1007/Bf00229411  0.636
1991 Lawrence MS, Redmond DE, Elsworth JD, Taylor JR, Roth RH. The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys. Life Sciences. 49: PL229-34. PMID 1836030 DOI: 10.1016/0024-3205(91)90299-Q  0.623
1991 Ida Y, Elsworth JD, Roth RH. Anxiogenic beta-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats. Pharmacology, Biochemistry, and Behavior. 39: 791-3. PMID 1784607 DOI: 10.1016/0091-3057(91)90166-Y  0.631
1991 Elsworth JD, Lawrence MS, Roth RH, Taylor JR, Mailman RB, Nichols DE, Lewis MH, Redmond DE. D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey. The Journal of Pharmacology and Experimental Therapeutics. 259: 595-600. PMID 1682479  0.571
1991 Taylor JR, Lawrence MS, Redmond DE, Elsworth JD, Roth RH, Nichols DE, Mailman RB. Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys. European Journal of Pharmacology. 199: 389-91. PMID 1680717 DOI: 10.1016/0014-2999(91)90508-N  0.628
1990 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate. Neuroscience Letters. 114: 316-22. PMID 2402341 DOI: 10.1016/0304-3940(90)90583-U  0.772
1990 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Redmond DE. Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys. Brain : a Journal of Neurology. 113: 617-37. PMID 2364263 DOI: 10.1093/Brain/113.3.617  0.611
1990 Tam SY, Elsworth JD, Bradberry CW, Roth RH. Mesocortical dopamine neurons: high basal firing frequency predicts tyrosine dependence of dopamine synthesis. Journal of Neural Transmission. General Section. 81: 97-110. PMID 2363911 DOI: 10.1007/Bf01245830  0.782
1990 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys. Brain Research. 513: 320-4. PMID 2350702 DOI: 10.1016/0006-8993(90)90474-P  0.767
1990 Berger P, Elsworth JD, Reith ME, Tanen D, Roth RH. Complex interaction of cocaine with the dopamine uptake carrier. European Journal of Pharmacology. 176: 251-2. PMID 2311671 DOI: 10.1016/0014-2999(90)90540-M  0.613
1990 Taylor JR, Elsworth JD, Roth RH, Collier TJ, Sladek JR, Redmond DE. Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys. Progress in Brain Research. 82: 543-59. PMID 2290957 DOI: 10.1016/S0079-6123(08)62645-X  0.663
1990 Gruen RJ, Elsworth JD, Roth RH. Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam. Brain Research. 514: 151-4. PMID 2162709 DOI: 10.1016/0006-8993(90)90449-L  0.576
1990 Deutch AY, Elsworth JD, Roth RH, Goldstein M, Deutsch AY. 3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation. Brain Research. 527: 96-102. PMID 2126479 DOI: 10.1016/0006-8993(90)91065-O  0.661
1990 Berger P, Elsworth JD, Arroyo J, Roth RH. Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens. European Journal of Pharmacology. 177: 91-4. PMID 1967129 DOI: 10.1016/0014-2999(90)90554-J  0.661
1990 Jatlow P, Hearn WL, Elsworth JD, Roth RH, Bradberry CW, Taylor JR. Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use. Nida Research Monograph. 105: 572-3. PMID 1876124  0.731
1989 Sladek JR, Redmond DE, Collier TJ, Elsworth JD, Roth RH. Transplantation advances in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 4: S120-5. PMID 2786143 DOI: 10.1002/Mds.870040513  0.592
1989 Elsworth JD, Deutch AY, Redmond DE, Taylor JR, Sladek JR, Roth RH. Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions. Neuroscience. 33: 323-31. PMID 2622529 DOI: 10.1016/0306-4522(89)90212-1  0.754
1988 Sladek JR, Redmond DE, Collier TJ, Blount JP, Elsworth JD, Taylor JR, Roth RH. Fetal dopamine neural grafts: extended reversal of methylphenyltetrahydropyridine-induced parkinsonism in monkeys. Progress in Brain Research. 78: 497-506. PMID 3266802 DOI: 10.1016/S0079-6123(08)60323-4  0.659
1988 Taylor JR, Elsworth JD, Garcia EJ, Grant SJ, Roth RH, Redmond DE. Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal. Psychopharmacology. 96: 121-34. PMID 3147472 DOI: 10.1007/Bf02431544  0.622
1988 Goldstein M, Lieberman AN, Helmer E, Koslow M, Ransohoff J, Elsworth JD, Roth RH, Deutch AY. Biochemical analysis of caudate nucleus biopsy samples from parkinsonian patients. Annals of Neurology. 24: 685-8. PMID 2904793 DOI: 10.1002/Ana.410240517  0.755
1987 Elsworth JD, Leahy DJ, Roth RH, Redmond DE. Homovanillic acid concentrations in brain, CSF and plasma as indicators of central dopamine function in primates. Journal of Neural Transmission. 68: 51-62. PMID 3806086 DOI: 10.1007/Bf01244639  0.637
1987 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF. Brain Research. 415: 293-9. PMID 3496938 DOI: 10.1016/0006-8993(87)90211-3  0.771
1987 Sladek JR, Redmond DE, Collier TJ, Haber SN, Elsworth JD, Deutch AY, Roth RH. Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism. Progress in Brain Research. 71: 309-23. PMID 3495818 DOI: 10.1016/S0079-6123(08)61833-6  0.755
1987 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life Sciences. 40: 193-202. PMID 3491946 DOI: 10.1016/0024-3205(87)90359-6  0.766
1987 Sladek JR, Collier TJ, Haber SN, Deutch AY, Elsworth JD, Roth RH, Redmond DE. Reversal of parkinsonism by fetal nerve cell transplants in primate brain. Annals of the New York Academy of Sciences. 495: 641-57. PMID 2886092 DOI: 10.1111/J.1749-6632.1987.Tb23706.X  0.7
1986 Elsworth JD, Redmond DE, Roth RH. Effect of morphine treatment and withdrawal on endogenous methionine- and leucine-enkephalin levels in primate brain. Biochemical Pharmacology. 35: 3415-7. PMID 3768031 DOI: 10.1016/0006-2952(86)90447-8  0.586
1986 Deutch AY, Elsworth JD, Goldstein M, Fuxe K, Redmond DE, Sladek JR, Roth RH. Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience Letters. 68: 51-6. PMID 3487756 DOI: 10.1016/0304-3940(86)90228-4  0.75
1986 Redmond DE, Sladek JR, Roth RH, Collier TJ, Elsworth JD, Deutch AY, Haber S. Transplants of primate neurons. Lancet. 2: 1046. PMID 2877218 DOI: 10.1016/S0140-6736(86)92664-4  0.676
1983 Elsworth JD, Roth RH, Redmond DE. Relative importance of 3-methoxy-4-hydroxyphenylglycol and 3,4-dihydroxyphenylglycol as norepinephrine metabolites in rat, monkey, and humans. Journal of Neurochemistry. 41: 786-93. PMID 6875564 DOI: 10.1111/J.1471-4159.1983.Tb04809.X  0.594
1983 Ko GN, Elsworth JD, Roth RH, Rifkin BG, Leigh H, Redmond DE. Panic-induced elevation of plasma MHPG levels in phobic-anxious patients. Effects of clonidine and imipramine. Archives of General Psychiatry. 40: 425-30. PMID 6838322 DOI: 10.1001/Archpsyc.1983.01790040079011  0.561
1982 Elsworth JD, Redmond DE, Roth RH. Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates. Brain Research. 235: 115-24. PMID 7188317 DOI: 10.1016/0006-8993(82)90200-1  0.581
1982 Roth RH, Elsworth JD, Redmond DE. Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates. The Journal of Clinical Psychiatry. 43: 42-6. PMID 6806253  0.591
1982 Swann AC, Elsworth JD, Charney DS, Jablons DM, Roth RH, Redmond DE, Maas JW. Brain catecholamine metabolites and behavior in morphine withdrawal. European Journal of Pharmacology. 86: 167-75. PMID 6297931 DOI: 10.1016/0014-2999(82)90314-4  0.605
1980 Glover V, Elsworth JD, Sandler M. Dopamine oxidation and its inhibition by (-)-deprenyl in man Journal of Neural Transmission, Supplement. 163-172. PMID 6776235  0.307
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