Shom Goel, M.D., Ph.D. - Publications

Affiliations: 
Cancer Biology Dana-Farber Cancer Institute, Boston, MA, United States 

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dietrich C, Trub A, Ahn A, Taylor M, Ambani K, Chan KT, Lu KH, Mahendra CA, Blyth C, Coulson R, Ramm S, Watt AC, Matsa SK, Bisi J, Strum J, ... ... Goel S, et al. INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors. Cancer Discovery. PMID 38047585 DOI: 10.1158/2159-8290.CD-23-0954  0.422
2023 Tolaney SM, Goel S, Nadal J, Denys H, Borrego MR, Litchfield LM, Liu J, Appiah AK, Chen Y, Andre F. Overall survival and exploratory biomarker analyses of abemaciclib plus trastuzumab with or without fulvestrant vs trastuzumab plus chemotherapy in HR+, HER2+ metastatic breast cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 37906649 DOI: 10.1158/1078-0432.CCR-23-1209  0.337
2023 Tolaney SM, Goel S, Appiah AK, Huynh T, Chen Y, André F. Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with HR+, HER2+ advanced breast cancer: plain language summary of the monarcHER study. Future Oncology (London, England). PMID 37788154 DOI: 10.2217/fon-2023-0078  0.349
2023 Ali LR, Garrido-Castro AC, Lenehan PJ, Bollenrucher N, Stump CT, Dougan M, Goel S, Shapiro GI, Tolaney SM, Dougan SK. PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of Experimental Medicine. 220. PMID 36688919 DOI: 10.1084/jem.20220729  0.305
2022 Goel S, Chandarlapaty S. Emerging Therapies for Breast Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 36617643 DOI: 10.1101/cshperspect.a041333  0.386
2022 Goel S, Tan AR, Rugo HS, Aftimos P, Andrić Z, Beelen A, Zhang J, Yi JS, Malik R, O'Shaughnessy J. Trilaciclib prior to gemcitabine plus carboplatin for metastatic triple-negative breast cancer: phase III PRESERVE 2. Future Oncology (London, England). PMID 36135712 DOI: 10.2217/fon-2022-0773  0.345
2022 Pernas S, Guerriero JL, Naumenko S, Goel S, Regan MM, Hu J, Harrison BT, Lynce F, Lin NU, Partridge A, Morikawa A, Hutchinson J, Mittendorf EA, Sokolov A, Overmoyer B. Early on-treatment transcriptional profiling as a tool for improving pathological response prediction in HER2-positive inflammatory breast cancer. Therapeutic Advances in Medical Oncology. 14: 17588359221113269. PMID 35923923 DOI: 10.1177/17588359221113269  0.344
2022 Wander SA, O'Brien N, Litchfield LM, O'Dea D, Morato Guimaraes C, Slamon DJ, Goel S. Targeting CDK4 and 6 in Cancer Therapy: Emerging Preclinical Insights Related to Abemaciclib. The Oncologist. PMID 35917168 DOI: 10.1093/oncolo/oyac138  0.394
2022 Goel S, Bergholz JS, Zhao JJ. Targeting CDK4 and CDK6 in cancer. Nature Reviews. Cancer. PMID 35304604 DOI: 10.1038/s41568-022-00456-3  0.631
2022 Watt AC, Goel S. Cellular mechanisms underlying response and resistance to CDK4/6 inhibitors in the treatment of hormone receptor-positive breast cancer. Breast Cancer Research : Bcr. 24: 17. PMID 35248122 DOI: 10.1186/s13058-022-01510-6  0.419
2021 Bergholtz H, Carter JM, Cesano A, Cheang MCU, Church SE, Divakar P, Fuhrman CA, Goel S, Gong J, Guerriero JL, Hoang ML, Hwang ES, Kuasne H, Lee J, Liang Y, et al. Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx Digital Spatial Profiler. Cancers. 13. PMID 34503266 DOI: 10.3390/cancers13174456  0.346
2021 Watt AC, Cejas P, DeCristo MJ, Metzger-Filho O, Lam EYN, Qiu X, BrinJones H, Kesten N, Coulson R, Font-Tello A, Lim K, Vadhi R, Daniels VW, Montero J, Taing L, ... ... Goel S, et al. CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nature Cancer. 2: 34-48. PMID 33997789 DOI: 10.1038/s43018-020-00135-y  0.626
2021 Alomran R, White M, Bruce M, Bressel M, Roache S, Karroum L, Hanna GG, Siva S, Goel S, David S. Stereotactic radiotherapy for oligoprogressive ER-positive breast cancer (AVATAR). Bmc Cancer. 21: 303. PMID 33757458 DOI: 10.1186/s12885-021-08042-w  0.394
2020 Tolaney SM, Wardley AM, Zambelli S, Hilton JF, Troso-Sandoval TA, Ricci F, Im SA, Kim SB, Johnston SR, Chan A, Goel S, Catron K, Chapman SC, Price GL, Yang Z, et al. Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with hormone receptor-positive, HER2-positive advanced breast cancer (monarcHER): a randomised, open-label, phase 2 trial. The Lancet. Oncology. PMID 32353342 DOI: 10.1016/S1470-2045(20)30112-1  0.446
2020 Bui KT, Willson ML, Goel S, Beith J, Goodwin A. Ovarian suppression for adjuvant treatment of hormone receptor-positive early breast cancer. The Cochrane Database of Systematic Reviews. 3: CD013538. PMID 32141074 DOI: 10.1002/14651858.Cd013538  0.4
2020 Goel S, Brauer HA, Ren Y, Gorman K, Osmani W, Pittenger J, Andrews C, Richardson ET, Mittendorf EA, Winer EP, Schnitt S, Tolaney SM. Abstract P4-06-01: Using multi-omic profiling to unravel the complexity of triple-negative breast cancer (TNBC) Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-06-01  0.425
2020 Herold CI, Trippa L, Li T, Do K, Bardia A, Anderson L, Montazeri K, Pittenger J, Andrews C, Mittendorf EA, Goel S, Winer EP, Shapiro GI, Tolaney SM. Abstract P3-14-03: A phase 1b study of the CDK4/6 inhibitor ribociclib in combination with the PD-1 inhibitor spartalizumab in patients with hormone receptor-positive metastatic breast cancer (HR+ MBC) and metastatic ovarian cancer (MOC) Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-14-03  0.425
2020 Tolaney S, Wardley AM, Zambelli S, Hilton J, Troso-Sandoval T, Ricci F, Im S, Kim S, Johnston S, Chan A, Goel S, Catron K, Yang Z, Gianford M, Price G, et al. Abstract P3-11-10: Health-related quality of life (HRQoL) in monarcHER: Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in HR+, HER2+ advanced breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P3-11-10  0.381
2019 Goel S, Tolaney SM. CDK4/6 inhibitors in breast cancer: a role in triple-negative disease? The Lancet. Oncology. PMID 31575504 DOI: 10.1016/S1470-2045(19)30627-8  0.465
2019 Goel S, Pernas S, Tan-Wasielewski Z, Barry WT, Bardia A, Rees R, Andrews C, Tahara RK, Trippa L, Mayer EL, Winer EP, Spring LM, Tolaney SM. Ribociclib Plus Trastuzumab in Advanced HER2-Positive Breast Cancer: Results of a Phase 1b/2 Trial. Clinical Breast Cancer. PMID 31235441 DOI: 10.1016/J.Clbc.2019.05.010  0.496
2019 Spring L, Goel S, Sutherland S, Supko JG, Juric D, Isakoff SJ, Mayer EL, Moy B, Tolaney SM, Bardia A. Trastuzumab emtansine (T-DM1) and ribociclib, an oral inhibitor of cyclin dependent kinase 4 and 6 (CDK 4/6), for patients with metastatic HER2-positive breast cancer. Journal of Clinical Oncology. 37: 1028-1028. DOI: 10.1200/Jco.2019.37.15_Suppl.1028  0.462
2019 Pernas S, Goel S, Harrison B, Hu J, Johnson N, Regan M, Chichester L, Nakhlis F, Schlosnagle E, Winship G, Guerriero J, Parsons H, Mittendorf E, Overmoyer B. Abstract PD3-08: Assessment of the tumor immune environment in inflammatory breast cancer treated with neoadjuvant dual-HER2 blockade Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-Pd3-08  0.405
2019 Goel S, Spring L, Rees R, Andrews C, Tahara R, Mayer E, Bardia A, Winer E, Tolaney S. Abstract P6-18-10: A phase 1b/2 study of ribociclib plus trastuzumab for the treatment of advanced, treatment-refractory HER2-positive breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P6-18-10  0.469
2019 Pernas S, Goel S, Johnson NT, Harrison BT, Guerriero JL, Hu J, Winship G, Sokolov A, Regan MM, Mittendorf EA, Overmoyer B. Early on-treatment vs pre-treatment tumour transcriptomes as predictors of response to neoadjuvant therapy for HER2-positive inflammatory breast cancer Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz239.031  0.419
2018 Goel S, DeCristo MJ, McAllister SS, Zhao JJ. CDK4/6 Inhibition in Cancer: Beyond Cell Cycle Arrest. Trends in Cell Biology. PMID 30061045 DOI: 10.1016/J.Tcb.2018.07.002  0.659
2018 Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, et al. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. Elife. 7. PMID 30059005 DOI: 10.7554/Elife.37184  0.601
2018 Pernas S, Tolaney SM, Winer EP, Goel S. CDK4/6 inhibition in breast cancer: current practice and future directions. Therapeutic Advances in Medical Oncology. 10: 1758835918786451. PMID 30038670 DOI: 10.1177/1758835918786451  0.536
2018 Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, et al. Author response: An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer Elife. DOI: 10.7554/Elife.37184.034  0.414
2018 DeCristo MJ, Goel S, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma C, Ramm S, Krop IE, et al. Abstract B04: CDK4/6 inhibition triggers an antitumor immune response Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-B04  0.465
2017 Goel S, DeCristo MJ, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma CX, Ramm S, Krop IE, et al. CDK4/6 inhibition triggers anti-tumour immunity. Nature. PMID 28813415 DOI: 10.1038/Nature23465  0.621
2017 Zhao Y, Ting K, Li J, Cogger VC, Chen J, Johansson-Percival A, Ngiow SF, Holst J, Grau GER, Goel S, Moller T, Dejana E, McCaughan GW, Smyth MJ, Ganss R, et al. Targeting vascular endothelial-cadherin in tumor-associated blood vessels  promotes T cell-mediated immunotherapy. Cancer Research. PMID 28655790 DOI: 10.1158/0008-5472.Can-16-3129  0.337
2017 Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, et al. The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Science Translational Medicine. 9. PMID 28539475 DOI: 10.1126/Scitranslmed.Aal4682  0.443
2017 Garrido-Castro AC, Goel S. CDK4/6 Inhibition in Breast Cancer: Mechanisms of Response and Treatment Failure. Current Breast Cancer Reports. 9: 26-33. PMID 28479958 DOI: 10.1007/S12609-017-0232-0  0.474
2017 Hydbring P, Wang Y, Fassl A, Li X, Matia V, Otto T, Choi YJ, Sweeney KE, Suski JM, Yin H, Bogorad RL, Goel S, Yuzugullu H, Kauffman KJ, Yang J, et al. Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers. Cancer Cell. 31: 576-590.e8. PMID 28399412 DOI: 10.1016/J.Ccell.2017.03.004  0.591
2017 Tolaney SM, Bourayou N, Goel S, Hossain A, Andre F. A phase II randomized study to compare abemaciclib plus trastuzumab with or without fulvestrant to standard of care chemotherapy plus trastuzumab in hormone receptor positive, HER2-positive advanced breast cancer (monarcHER). Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.Tps1109  0.526
2017 Spring L, Goel S, Juric D, Isakoff SJ, Haddad S, Habin KR, Krop IE, Moy B, Tolaney SM, Bardia A. Trastuzumab emtansine (T-DM1) and ribociclib, an oral inhibitor of cyclin dependent kinase 4 and 6 (CDK 4/6), for patients with metastatic HER2-positive breast cancer: Phase 1b clinical trial. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.Tps1106  0.517
2017 Filho OM, Goel S, Barry WT, Hamilton EP, Tolaney SM, Yardley DA, Rees R, Demeo M, Mills C, Hafner M, Winer EP, Zhao J, Krop IE. A mouse-human phase I co-clinical trial of taselisib in combination with TDM1 in advanced HER2-positive breast cancer (MBC). Journal of Clinical Oncology. 35: 1030-1030. DOI: 10.1200/Jco.2017.35.15_Suppl.1030  0.606
2017 Jacene H, Overmoyer B, Schlosnagle E, Abbott A, Yeh E, Paolino J, Goel S, Culhane A, Bellon J, Nakhlis F, Hirshfield-Bartek J, Abbeele AVd. Abstract OT2-02-03: Pilot study of zirconium-89 bevacizumab positron emission tomography for imaging angiogenesis in patients with inflammatory breast carcinoma receiving preoperative chemotherapy Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Ot2-02-03  0.404
2017 Overmoyer B, Goel S, Regan M, Hirshfield-Bartek J, Schlosnagel E, Yeh E, Qin L, Bellon J, Nakhlis F, Jacene H, Winer E. Abstract OT1-01-07: A phase 2 study of eribulin followed by doxorubicin and cyclophosphamide as preoperative therapy for HER2-negative inflammatory breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Ot1-01-07  0.439
2017 Ferraro GB, Kodack DP, Askoxylakis V, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao AZ, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, et al. Abstract 5008: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation Cancer Research. 77: 5008-5008. DOI: 10.1158/1538-7445.Am2017-5008  0.458
2017 DeCristo MJ, Goel S, Watt AC, BrinJones H, Sceneay J, Li B, Ubellacker JM, Xie S, Ramm S, Kim H, McAllister SS, Zhao JJ. Abstract 1634: CDK4/6 inhibition directly enhances an anti-tumor immune response in breast cancer Cancer Research. 77: 1634-1634. DOI: 10.1158/1538-7445.Am2017-1634  0.47
2016 Goel S, Zhao JJ. CDK4/6 inhibition: the late harvest cycle begins. Oncotarget. PMID 27391058 DOI: 10.18632/Oncotarget.9576  0.635
2016 Goel S, Krop IE. PIK3CA mutations in HER2-positive breast cancer - an ongoing conundrum. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 27358378 DOI: 10.1093/Annonc/Mdw246  0.412
2016 Ni J, Ramkissoon SH, Xie S, Goel S, Stover DG, Guo H, Luu V, Marco E, Ramkissoon LA, Kang YJ, Hayashi M, Nguyen QD, Ligon AH, Du R, Claus EB, et al. Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases. Nature Medicine. PMID 27270588 DOI: 10.1038/Nm.4120  0.667
2016 Goel S, Wang Q, Watt AC, Tolaney SM, Dillon DA, Li W, Ramm S, Palmer AC, Yuzugullu H, Varadan V, Tuck D, Harris LN, Wong KK, Liu XS, Sicinski P, et al. Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors. Cancer Cell. 29: 255-269. PMID 26977878 DOI: 10.1016/J.Ccell.2016.02.006  0.674
2016 Tolaney SM, Bourayou N, Goel S, Forrester T, André F. monarcHER: A phase 2 randomized open-label study of abemaciclib plus trastuzumab (T) with or without fulvestrant (F) compared to standard-of-care chemotherapy of physician's choice plus T in women with HR + , HER2+ advanced breast cancer Annals of Oncology. 27. DOI: 10.1093/Annonc/Mdw365.93  0.382
2015 Tolaney SM, Boucher Y, Duda DG, Martin JD, Seano G, Ancukiewicz M, Barry WT, Goel S, Lahdenrata J, Isakoff SJ, Yeh ED, Jain SR, Golshan M, Brock J, Snuderl M, et al. Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients. Proceedings of the National Academy of Sciences of the United States of America. 112: 14325-14330. PMID 26578779 DOI: 10.1073/Pnas.1518808112  0.419
2015 Goel S, Winer EP. POINT: HER2-Targeted Combinations in Advanced HER2-Positive Breast Cancer. Oncology (Williston Park, N.Y.). 29. PMID 26573058  0.351
2015 Tiwari V, Pande SC, Verma K, Goel S. Spinal metastasis of breast cancer presenting after 25 years: An extremely rare presentation. The Gulf Journal of Oncology. 1: 24-7. PMID 26499826  0.346
2015 Swami U, Shah U, Goel S. Eribulin in Cancer Treatment. Marine Drugs. 13: 5016-58. PMID 26262627 DOI: 10.3390/md13085016  0.354
2015 Tiwari R, Pandey SK, Goel S, Bhatia V, Shukla S, Jing X, Dhanasekaran SM, Ateeq B. SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression. Oncogenesis. 4: e162. PMID 26258891 DOI: 10.1038/oncsis.2015.23  0.352
2015 Goel S, Krop IE. Deciphering the role of phosphatidylinositol 3-kinase mutations in human epidermal growth factor receptor 2-positive breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1407-9. PMID 25800754 DOI: 10.1200/Jco.2014.60.0742  0.506
2015 Ager EI, Kozin SV, Kirkpatrick ND, Seano G, Kodack DP, Askoxylakis V, Huang Y, Goel S, Snuderl M, Muzikansky A, Finkelstein DM, Dransfield DT, Devy L, Boucher Y, Fukumura D, et al. Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy. Journal of the National Cancer Institute. 107. PMID 25710962 DOI: 10.1093/Jnci/Djv017  0.311
2015 Goel S, Guo H, Barry W, Murray B, Lynch J, Bastick P, Chantrill L, Kiely B, Bell R, Abdi E, Rutovitz J, Asghari R, Sullivan A, Harrison M, Kohonen-Corish M, et al. Abstract P4-15-02: Clinical, biochemical, and genomic predictors of trastuzumab-related cardiotoxicity: Results of CATS Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-15-02  0.375
2015 Goel S, Tolaney S. Optimizing the Management of Metastatic HER2-Positive Breast Cancer Current Breast Cancer Reports. 7: 190-202. DOI: 10.1007/S12609-015-0191-2  0.426
2015 Lim E, Goel S, Winer EP. Adjuvant chemotherapy in breast cancer Breast Disease: Comprehensive Management. 335-351. DOI: 10.1007/978-1-4939-1145-5_23  0.347
2013 Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, et al. Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. Journal of the National Cancer Institute. 105: 1188-201. PMID 23899555 DOI: 10.1093/Jnci/Djt164  0.374
2013 Huang Y, Goel S, Duda DG, Fukumura D, Jain RK. Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Cancer Research. 73: 2943-8. PMID 23440426 DOI: 10.1158/0008-5472.Can-12-4354  0.356
2013 Boucher Y, Martin JD, Tolaney SM, Ancukiewicz M, Seano G, Goel S, Yeh E, Meyer JE, Isakoff SJ, Duda DG, Winer EP, Krop IE, Jain RK. Differential changes in tissue biomarkers after bevacizumab (BEV) alone in a neoadjuvant study of BEV and chemotherapy in ER+ breast cancer (BC) versus triple-negative breast cancer (TNBC) patients (pts). Journal of Clinical Oncology. 31: 1065-1065. DOI: 10.1200/Jco.2013.31.15_Suppl.1065  0.387
2013 Boucher Y, Martin JD, Tolaney SM, Seano G, Goel S, Ancukiewicz M, Isakoff SJ, Winer EP, Krop IE, Jain RK. Abstract LB-76: Tissue biomarkers and interstitial fluid pressure in a phase II study of preoperative (preop) bevacizumab (bev) followed by dose-dense doxorubicin (A)/cyclophosphamide (C)/paclitaxel (T) in combination with bev in HER2-negative operable breast cancer (BC) Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-76  0.372
2013 Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK. Abstract C1: Functional normalization of the breast cancer vasculature through activation of Tie2 using a vascular-endothelial protein tyrosine phosphatase inhibitor. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C1  0.466
2012 Kodack DP, Chung E, Yamashita H, Incio J, Duyverman AM, Song Y, Farrar CT, Huang Y, Ager E, Kamoun W, Goel S, Snuderl M, Lussiez A, Hiddingh L, Mahmood S, et al. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proceedings of the National Academy of Sciences of the United States of America. 109: E3119-27. PMID 23071298 DOI: 10.1073/Pnas.1216078109  0.45
2012 Goel S, Fukumura D, Jain RK. Normalization of the tumor vasculature through oncogenic inhibition: an emerging paradigm in tumor biology. Proceedings of the National Academy of Sciences of the United States of America. 109: E1214. PMID 22550180 DOI: 10.1073/Pnas.1203794109  0.309
2012 Goel S, Wong AH, Jain RK. Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease. Cold Spring Harbor Perspectives in Medicine. 2: a006486. PMID 22393532 DOI: 10.1101/Cshperspect.A006486  0.322
2012 Tolaney SM, Duda DG, Boucher Y, Goel S, Martin J, Ancukiewicz M, Potler H, Incio J, Ligibel JA, Isakoff SJ, Fukumura D, Winer EP, Krop IE, Jain RK. A phase II study of preoperative (preop) bevacizumab (bev) followed by dose-dense (dd) doxorubicin (A)/cyclophosphamide (C)/paclitaxel (T) in combination with bev in HER2-negative operable breast cancer (BC). Journal of Clinical Oncology. 30: 1026-1026. DOI: 10.1200/Jco.2012.30.15_Suppl.1026  0.325
2012 Kodack D, Chung E, Yamashita H, Incio J, Peters A, Song Y, Ager E, Huang Y, Farrar C, Lussiez A, Goel S, Snuderl M, Kamoun W, Hiddingh L, Tannous B, et al. Abstract P3-12-03: Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-12-03  0.478
2011 Ghamande SA, Lin C, Cho DC, Coleman TA, Chaudhary I, Cleary JM, Silverman MH, Kuo M, Mach W, Tseng Y, Hsu SC, Goel S. A phase I study of the novel DNA topoisomerase-1 inhibitor, TLC388, administered intravenously to patients with advanced solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e13618. PMID 28023558 DOI: 10.1200/Jco.2011.29.15_Suppl.E13618  0.336
2011 Goel S, Lynch J, Chantrill LA, Rutovitz JJ, Murray B, Abdi EA, Bell R, Sullivan AL, Goldrick A, Hayes TM, Asghari G, Wilcken N, McCarthy NJ, Beith JM. Serum NT pro-BNP and individual genetic polymorphisms as predictors of trastuzumab-related cardiotoxicity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: TPS121. PMID 28022939 DOI: 10.1200/Jco.2011.29.15_Suppl.Tps121  0.356
2011 Goel S, Simes RJ, Beith JM. Exploratory analysis of cardiac biomarkers in women with normal cardiac function receiving trastuzumab for breast cancer. Asia-Pacific Journal of Clinical Oncology. 7: 276-80. PMID 21884439 DOI: 10.1111/J.1743-7563.2011.01422.X  0.303
2011 Goel S, Duda DG, Xu L, Munn LL, Boucher Y, Fukumura D, Jain RK. Normalization of the vasculature for treatment of cancer and other diseases. Physiological Reviews. 91: 1071-121. PMID 21742796 DOI: 10.1152/Physrev.00038.2010  0.374
2011 Hiratsuka S, Goel S, Kamoun WS, Maru Y, Fukumura D, Duda DG, Jain RK. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 108: 3725-30. PMID 21321210 DOI: 10.1073/Pnas.1100446108  0.355
2011 Goel S, Chirgwin J, Francis P, Stuart-Harris R, Dewar J, Mileshkin L, Snyder R, Michael M, Koczwara B. Rational use of trastuzumab in metastatic and locally advanced breast cancer: implications of recent research. Breast (Edinburgh, Scotland). 20: 101-10. PMID 21183347 DOI: 10.1016/J.Breast.2010.11.008  0.465
2011 Hiratsuka S, Duda DG, Huang Y, Goel S, Sugiyama T, Nagasawa T, Fukumura D, Jain RK. C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 302-7. PMID 21173223 DOI: 10.1073/Pnas.1016917108  0.351
2011 Liu J, Liao S, Diop B, Chen W, Goel S, Huang Y, Boucher Y, Jain RK, Xu L. Abstract 715: TGF-beta blockade improves the distribution and efficacy of chemotherapeutic agents in breast carcinoma Cancer Research. 71: 715-715. DOI: 10.1158/1538-7445.Am2011-715  0.339
2009 Goel S, Sharma R, Hamilton A, Beith J. LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women. The Cochrane Database of Systematic Reviews. CD004562. PMID 19821328 DOI: 10.1002/14651858.Cd004562.Pub4  0.412
2009 Goel S, Hamilton A. Cancer drugs in the real world Asia-Pacific Journal of Clinical Oncology. 5: 1-3. DOI: 10.1111/J.1743-7563.2009.01195.X  0.312
2009 Goel S, Abdi E, Lewis CR, Links M, Begbie S, Clingan P, Ganju V, Beith J. Phase II study of gemcitabine and docetaxel in combination for the treatment of metastatic breast cancer Asia-Pacific Journal of Clinical Oncology. 5: 32-38. DOI: 10.1111/J.1743-7563.2009.01189.X  0.416
2008 Goel S, Simes RJ, Beith JM. An exploratory analysis of cardiac biomarkers in women receiving trastuzumab Journal of Clinical Oncology. 26: 20557-20557. DOI: 10.1200/Jco.2008.26.15_Suppl.20557  0.36
Show low-probability matches.