Fen Wang, PhD - Publications

Affiliations: 
Center for Cancer and Stem Cell Biology Texas A & M Health Science Center, Bryan, TX, United States 

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fan Z, Ma J, Pan X, Zhao L, Wu Y, Lin H, Zhao Y, Jiang H, Pan T, Li X, Wang F, Wang C. Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells. International Journal of Cancer. PMID 34985768 DOI: 10.1002/ijc.33922  0.323
2020 Wang F, Li X, Wang C. Editorial: Resident and Ectopic FGF Signaling in Development and Disease. Frontiers in Cell and Developmental Biology. 8: 720. PMID 32984306 DOI: 10.3389/Fcell.2020.00720  0.32
2020 Labanca E, Vazquez ES, Corn PG, Roberts JM, Wang F, Logothetis CJ, Navone NM. Fibroblast growth factors signaling in bone metastasis. Endocrine-Related Cancer. PMID 32369771 DOI: 10.1530/Erc-19-0472  0.332
2020 Jiang G, Liang X, Huang Y, Lan Z, Zhang Z, Su Z, Fang Z, Lai Y, Yao W, Liu T, Hu, Wang F, Huang H, Liu L, Jiang X. p62 promotes proliferation, apoptosis‑resistance and invasion of prostate cancer cells through the Keap1/Nrf2/ARE axis. Oncology Reports. PMID 32323805 DOI: 10.3892/Or.2020.7527  0.383
2020 Chen G, Cai ZD, Lin ZY, Wang C, Liang YX, Han ZD, He HC, Mo RJ, Lu JM, Pan B, Wu CL, Wang F, Zhong WD. ARNT-dependent CCR8 reprogrammed LDH isoform expression correlates with poor clinical outcomes of prostate cancer. Molecular Carcinogenesis. PMID 32319143 DOI: 10.1002/Mc.23201  0.394
2020 Li W, Dai Y, Shi B, Yue F, Zou J, Xu G, Jiang X, Wang F, Zhou X, Liu L. LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas. Oncogene. PMID 32203162 DOI: 10.1038/S41388-020-1257-9  0.327
2019 Riaz SK, Ke Y, Wang F, Kayani MA, Malik MFA. Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells. Scientific Reports. 9: 6620. PMID 31036836 DOI: 10.1038/S41598-019-43093-X  0.317
2019 Wang C, Liu Z, Ke Y, Wang F. Intrinsic FGFR2 and Ectopic FGFR1 Signaling in the Prostate and Prostate Cancer. Frontiers in Genetics. 10: 12. PMID 30761180 DOI: 10.3389/Fgene.2019.00012  0.463
2019 Ji S, Liu Q, Zhang S, Chen Q, Wang C, Zhang W, Xiao C, Li Y, Nian C, Li J, Li J, Geng J, Hong L, Xie C, He Y, ... ... Wang F, et al. FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis. Developmental Cell. PMID 30745141 DOI: 10.1016/J.Devcel.2018.12.021  0.363
2019 Li H, Mao Y, Bouaziz M, Yu H, Qu X, Wang F, Feng GS, Shawber C, Zhang X. Lens differentiation is controlled by the balance between PDGF and FGF signaling. Plos Biology. 17: e3000133. PMID 30716082 DOI: 10.1371/Journal.Pbio.3000133  0.437
2018 Wang C, Ke Y, Liu S, Pan S, Liu Z, Zhang H, Fan Z, Zhou C, Liu J, Wang F. Ectopic fibroblast growth factor receptor 1 promotes inflammation by promoting nuclear factor-κB signaling in prostate cancer cells. The Journal of Biological Chemistry. PMID 30093411 DOI: 10.1074/Jbc.Ra118.002907  0.448
2018 Liu J, Chen G, Liu Z, Liu S, Cai Z, You P, Ke Y, Lai L, Huang Y, Gao H, Zhao L, Pelicano H, Huang P, McKeehan WL, Wu CL, ... ... Wang F, et al. Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer. Cancer Research. PMID 29891507 DOI: 10.1158/0008-5472.Can-17-3226  0.583
2018 Li Q, Alsaidan OA, Ma Y, Kim S, Liu J, Albers T, Liu K, Beharry Z, Zhao S, Wang F, Lebedyeva I, Cai H. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression. The Journal of Biological Chemistry. PMID 29540482 DOI: 10.1074/Jbc.Ra117.000940  0.436
2018 Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/Elife.32586  0.391
2017 Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X. Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. Plos Genetics. 13: e1007047. PMID 29028795 DOI: 10.1371/Journal.Pgen.1007047  0.415
2017 Nandi S, Gutin G, Blackwood CA, Kamatkar NG, Lee KW, Fishell G, Wang F, Goldfarb M, Hébert JM. FGF-dependent, context-driven role for FRS adapters in the early telencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28483978 DOI: 10.1523/Jneurosci.2931-16.2017  0.387
2017 Lin H, Fang Z, Su Y, Li P, Wang J, Liao H, Hu Q, Ye C, Fang Y, Luo Q, Lin Z, Pan C, Wang F, Zhang ZY. DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting β-catenin Signaling to Induce Expression of VEGFA. Ebiomedicine. PMID 28330603 DOI: 10.1016/J.Ebiom.2017.03.012  0.325
2016 Mathew G, Hannan A, Hertzler-Schaefer K, Wang F, Feng GS, Zhong J, Zhao JJ, Downward J, Zhang X. Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799550 DOI: 10.1073/Pnas.1604450113  0.337
2016 Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. PMID 27374105 DOI: 10.18632/Oncotarget.10294  0.389
2016 Li X, Wang C, Xiao J, McKeehan WL, Wang F. Fibroblast growth factors, old kids on the new block. Seminars in Cell & Developmental Biology. PMID 26768548 DOI: 10.1016/J.Semcdb.2015.12.014  0.585
2016 Li W, Zou J, Yue F, Song K, Chen Q, McKeehan WL, Wang F, Xu G, Huang H, Yi J, Liu L. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. PMID 26750654 DOI: 10.1111/Acel.12441  0.487
2015 Shi M, Zhang Y, Liu L, Zhang T, Han F, Cleveland J, Wang F, McKeehan WL, Li Y, Zhang D. MAP1S regulates the phagocytosis of bacteria and TLR signaling. The Journal of Biological Chemistry. PMID 26565030 DOI: 10.1074/Jbc.M115.687376  0.411
2015 Yue F, Li W, Zou J, Chen Q, Xu G, Huang H, Xu Z, Zhang S, Gallinari P, Wang F, McKeehan WL, Liu L. Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin. Aging. 7: 839-853. PMID 26540094  0.383
2015 Lin L, Fang Z, Lin H, You H, Wang J, Su Y, Wang F, Zhang ZY. Depletion of Cks1 and Cks2 expression compromises cell proliferation and enhance chemotherapy-induced apoptosis in HepG2 cells. Oncology Reports. PMID 26531156 DOI: 10.3892/Or.2015.4372  0.35
2015 Huang Y, Jin C, Hamana T, Liu J, Wang C, An L, McKeehan WL, Wang F. Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression. International Journal of Biological Sciences. 11: 948-60. PMID 26157349 DOI: 10.7150/Ijbs.12468  0.586
2015 Liu J, You P, Chen G, Fu X, Zeng X, Wang C, Huang Y, An L, Wan X, Navone N, Wu CL, McKeehan WL, Zhang Z, Zhong W, Wang F. Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients. Oncogene. PMID 26096936 DOI: 10.1038/Onc.2015.239  0.591
2015 Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, McKeehan WL, Wang F. Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment. The Journal of Biological Chemistry. 290: 17745-52. PMID 26032419 DOI: 10.1074/Jbc.M115.661033  0.533
2015 Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, Jin C, Zhang Z, McKeehan WL, Wang F. Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment. The Journal of Biological Chemistry. 290: 17753-61. PMID 26032417 DOI: 10.1074/Jbc.M115.661066  0.546
2015 Ho TH, Liu XD, Huang Y, Warneke CL, Johnson MM, Hoang A, Tamboli P, Wang F, Jonasch E. The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma. Bmc Cancer. 15: 304. PMID 25900027 DOI: 10.1186/S12885-015-1302-1  0.376
2015 Lin H, Liu W, Fang Z, Liang X, Li J, Bai Y, Lin L, You H, Pei Y, Wang F, Zhang ZY. Overexpression of DHX32 contributes to the growth and metastasis of colorectal cancer. Scientific Reports. 5: 9247. PMID 25782664 DOI: 10.1038/Srep09247  0.312
2015 Xu C, Li W, Qiu P, Xia Y, Du X, Wang F, Shen L, Chen Q, Zhao Y, Jin R, Wu J, Liang G, Li X. The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. Anti-Cancer Drugs. 26: 379-87. PMID 25521558 DOI: 10.1097/Cad.0000000000000195  0.327
2015 Wang F, Luo Y, McKeehan WL. The FGF signaling axis in prostate tumorigenesis Molecular Oncology: Causes of Cancer and Targets For Treatment. 190-203. DOI: 10.1017/CBO9781139046947.017  0.488
2014 Tien JC, Liao L, Liu Y, Liu Z, Lee DK, Wang F, Xu J. The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. International Journal of Biological Sciences. 10: 1116-27. PMID 25332686 DOI: 10.7150/Ijbs.10236  0.408
2014 Wan X, Corn PG, Yang J, Palanisamy N, Starbuck MW, Efstathiou E, Tapia EM, Tapia EM, Zurita AJ, Aparicio A, Ravoori MK, Vazquez ES, Robinson DR, Wu YM, Cao X, ... ... Wang F, et al. Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases. Science Translational Medicine. 6: 252ra122. PMID 25186177 DOI: 10.1126/Scitranslmed.3009332  0.539
2014 Zhao S, Zhang Y, Zhang Q, Wang F, Zhang D. Toll-like receptors and prostate cancer. Frontiers in Immunology. 5: 352. PMID 25101092 DOI: 10.3389/Fimmu.2014.00352  0.337
2014 Wang C, Yang C, Chang JY, You P, Li Y, Jin C, Luo Y, Li X, McKeehan WL, Wang F. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity. Current Molecular Medicine. 14: 703-11. PMID 25056539 DOI: 10.2174/1566524014666140724095112  0.57
2014 Jiang X, Zhong W, Huang H, He H, Jiang F, Chen Y, Yue F, Zou J, Li X, He Y, You P, Yang W, Lai Y, Wang F, Liu L. Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients. Molecular Carcinogenesis. PMID 25043940 DOI: 10.1002/Mc.22193  0.321
2014 Yin Y, Wang H, Liu K, Wang F, Ye X, Liu M, Xiang R, Liu N, Liu L. Knockdown of H19 enhances differentiation capacity to epidermis of parthenogenetic embryonic stem cells. Current Molecular Medicine. 14: 737-748. PMID 24894171 DOI: 10.2174/1566524014666140724101035  0.308
2014 Jiang X, Li X, Huang H, Jiang F, Lin Z, He H, Chen Y, Yue F, Zou J, He Y, You P, Wang W, Yang W, Zhao H, Lai Y, ... Wang F, et al. Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer. Cancer. 120: 1228-36. PMID 24390809 DOI: 10.1002/Cncr.28551  0.341
2014 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X. Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development. Journal of Cell Science. 127: 571-82. PMID 24284065 DOI: 10.1242/Jcs.134478  0.38
2013 Warneke CL, Hoang A, Tamboli P, Wang F, Jonasch E. The role of FGF signaling in VEGF-pathway targeted therapy resistance: Data from patients and model systems. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 386. PMID 28136881 DOI: 10.1200/Jco.2013.31.6_Suppl.386  0.358
2013 Yang Z, Hai B, Qin L, Ti X, Shangguan L, Zhao Y, Wiggins L, Liu Y, Feng JQ, Chang JY, Wang F, Liu F. Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner. Molecular and Cellular Biology. 33: 4732-44. PMID 24081330 DOI: 10.1128/Mcb.00456-13  0.332
2013 Corn PG, Wang F, McKeehan WL, Navone N. Targeting fibroblast growth factor pathways in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5856-66. PMID 24052019 DOI: 10.1158/1078-0432.Ccr-13-1550  0.575
2013 Chang JY, Wang C, Liu J, Huang Y, Jin C, Yang C, Hai B, Liu F, D'Souza RN, McKeehan WL, Wang F. Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells. The Journal of Biological Chemistry. 288: 28952-61. PMID 23979135 DOI: 10.1074/Jbc.M113.506873  0.568
2013 Chang JY, Wang C, Jin C, Yang C, Huang Y, Liu J, McKeehan WL, D'Souza RN, Wang F. Self-renewal and multilineage differentiation of mouse dental epithelial stem cells. Stem Cell Research. 11: 990-1002. PMID 23906788 DOI: 10.1016/J.Scr.2013.06.008  0.526
2013 Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li X. Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. The Journal of Biological Chemistry. 288: 22174-83. PMID 23754280 DOI: 10.1074/Jbc.M113.463620  0.575
2013 Gay D, Kwon O, Zhang Z, Spata M, Plikus MV, Holler PD, Ito M, Yang Z, Treffeisen E, Kim CD, Nace A, Zhang X, Baratono S, Wang F, Ornitz DM, et al. Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding. Nature Medicine. 19: 916-23. PMID 23727932 DOI: 10.1038/Nm.3181  0.342
2013 Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X. Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development (Cambridge, England). 140: 2711-23. PMID 23720040 DOI: 10.1242/Dev.089987  0.333
2013 Tien JC, Liu Z, Liao L, Wang F, Xu Y, Wu YL, Zhou N, Ittmann M, Xu J. The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer. Cancer Research. 73: 3997-4008. PMID 23650284 DOI: 10.1158/0008-5472.Can-12-3929  0.421
2013 Yang C, Lu W, Lin T, You P, Ye M, Huang Y, Jiang X, Wang C, Wang F, Lee MH, Yeung SC, Johnson RL, Wei C, Tsai RY, Frazier ML, et al. Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress. Bmc Gastroenterology. 13: 67. PMID 23590285 DOI: 10.1186/1471-230X-13-67  0.486
2013 Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR. FGFR1 is essential for prostate cancer progression and metastasis. Cancer Research. 73: 3716-24. PMID 23576558 DOI: 10.1158/0008-5472.Can-12-3274  0.421
2013 Guan JL, Simon AK, Prescott M, Menendez JA, Liu F, Wang F, Wang C, Wolvetang E, Vazquez-Martin A, Zhang J. Autophagy in stem cells. Autophagy. 9: 830-49. PMID 23486312 DOI: 10.4161/Auto.24132  0.325
2013 Zhang T, Liu J, Zhang J, Thekkethottiyil EB, Macatee TL, Ismat FA, Wang F, Stoller JZ. Jun is required in Isl1-expressing progenitor cells for cardiovascular development. Plos One. 8: e57032. PMID 23437302 DOI: 10.1371/Journal.Pone.0057032  0.323
2013 Wan X, Corn P, Yang J, Efstathiou E, Tapia EMLN, Wang F, McKeehan W, Logothetis C, Troncoso P, Navone NM. Abstract 2436: Fibroblast growth factor receptor blockade in prostate cancer bone metastases. Cancer Research. 73: 2436-2436. DOI: 10.1158/1538-7445.Am2013-2436  0.543
2012 Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, ... ... Wang F, et al. Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex. Science Translational Medicine. 4: 162ra153. PMID 23197570 DOI: 10.1126/Scitranslmed.3004690  0.515
2012 Madakashira BP, Kobrinski DA, Hancher AD, Arneman EC, Wagner BD, Wang F, Shin H, Lovicu FJ, Reneker LW, Robinson ML. Frs2α enhances fibroblast growth factor-mediated survival and differentiation in lens development. Development (Cambridge, England). 139: 4601-12. PMID 23136392 DOI: 10.1242/Dev.081737  0.396
2012 Yang C, Wang C, Ye M, Jin C, He W, Wang F, McKeehan WL, Luo Y. Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress. Nutrition & Metabolism. 9: 94. PMID 23106963 DOI: 10.1186/1743-7075-9-94  0.522
2012 Zhou J, Qin L, Tien JC, Gao L, Chen X, Wang F, Hsieh JT, Xu J. Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner. The Journal of Biological Chemistry. 287: 17248-56. PMID 22465996 DOI: 10.1074/Jbc.M111.336909  0.406
2012 Yang C, Jin C, Li X, Wang F, McKeehan WL, Luo Y. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB. Plos One. 7: e33870. PMID 22442730 DOI: 10.1371/Journal.Pone.0033870  0.529
2012 Zhang J, Liu J, Liu L, McKeehan WL, Wang F. The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy. Autophagy. 8: 690-1. PMID 22302007 DOI: 10.4161/Auto.19290  0.555
2012 Liu L, McKeehan WL, Wang F, Xie R. MAP1S enhances autophagy to suppress tumorigenesis. Autophagy. 8: 278-80. PMID 22301994 DOI: 10.4161/Auto.8.2.18939  0.456
2012 Yang X, Li Q, Lin X, Ma Y, Yue X, Tao Z, Wang F, Mckeehan WL, Wei L, Schwartz RJ, Chang J. Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2105-16. PMID 22278938 DOI: 10.1096/Fj.11-201319  0.511
2012 Zhang J, Liu J, Huang Y, Chang JY, Liu L, McKeehan WL, Martin JF, Wang F. FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity. Circulation Research. 110: e29-39. PMID 22207710 DOI: 10.1161/Circresaha.111.255950  0.568
2011 Ho TH, Wang F, Hoang A, Tamboli P, Jonasch E. Fibroblast growth factor receptor 1 (FGFR1) expression and activation in clear cell renal cell carcinoma (ccRCC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e15015. PMID 28020567 DOI: 10.1200/Jco.2011.29.15_Suppl.E15015  0.391
2011 Xie R, Wang F, McKeehan WL, Liu L. Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. Cancer Research. 71: 7537-46. PMID 22037873 DOI: 10.1158/0008-5472.Can-11-2170  0.454
2011 Lin X, Zhang Y, Liu L, McKeehan WL, Shen Y, Song S, Wang F. FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts. International Journal of Biological Sciences. 7: 1114-21. PMID 21927580 DOI: 10.7150/Ijbs.7.1114  0.573
2011 Yin Y, Wang F, Ornitz DM. Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development. Development (Cambridge, England). 138: 3169-77. PMID 21750028 DOI: 10.1242/Dev.065110  0.375
2011 Jin C, Yang C, Wu X, Wang F, McKeehan WL. FGFR3-expressing smooth muscle-like stromal cells differentiate in response to FGFR2IIIb-expressing prostate tumor cells and delay tumor progression. In Vitro Cellular & Developmental Biology. Animal. 47: 500-5. PMID 21691921 DOI: 10.1007/S11626-011-9432-5  0.543
2011 Valiyeva F, Jiang F, Elmaadawi A, Moussa M, Yee SP, Raptis L, Izawa JI, Yang BB, Greenberg NM, Wang F, Xuan JW. Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models. Molecular Cancer Therapeutics. 10: 1229-40. PMID 21593385 DOI: 10.1158/1535-7163.Mct-11-0077  0.394
2011 Kobayashi M, Huang Y, Jin C, Luo Y, Okamoto T, Wang F, McKeehan WL. FGFR1 abrogates inhibitory effect of androgen receptor concurrent with induction of androgen-receptor variants in androgen receptor-negative prostate tumor epithelial cells. The Prostate. 71: 1691-700. PMID 21446013 DOI: 10.1002/Pros.21386  0.521
2011 Wang F. Modeling human prostate cancer in genetically engineered mice Progress in Molecular Biology and Translational Science. 100: 1-49. PMID 21377623 DOI: 10.1016/B978-0-12-384878-9.00001-7  0.335
2011 Xie R, Nguyen S, McKeehan K, Wang F, McKeehan WL, Liu L. Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. The Journal of Biological Chemistry. 286: 10367-77. PMID 21262964 DOI: 10.1074/Jbc.M110.206532  0.458
2011 Wang F, McKeehan WL, Shen MM, Abate-Shen C. Genetically engineered mouse models in prostate cancer research Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances. 219-282. DOI: 10.1142/9789814329460_0009  0.624
2010 Zhang J, Chang JY, Huang Y, Lin X, Luo Y, Schwartz RJ, Martin JF, Wang F. The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circulation Research. 107: 1209-19. PMID 20847311 DOI: 10.1161/Circresaha.110.225318  0.348
2010 Luo Y, Yang C, Lu W, Xie R, Jin C, Huang P, Wang F, McKeehan WL. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. The Journal of Biological Chemistry. 285: 30069-78. PMID 20657013 DOI: 10.1074/Jbc.M110.148288  0.593
2010 Zhang L, Zhang B, Valdez JM, Wang F, Ittmann M, Xin L. Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells (Dayton, Ohio). 28: 1260-9. PMID 20517984 DOI: 10.1002/Stem.455  0.39
2010 Lin Y, Wang F. FGF signalling in prostate development, tissue homoeostasis and tumorigenesis. Bioscience Reports. 30: 285-91. PMID 20406196 DOI: 10.1042/BSR20100020  0.321
2010 Wan X, Yang J, Starbuck MW, Ravoori MK, Lu J, Kundra V, Maity S, Wang F, Navone NM. Abstract 344: Targeting fibroblast growth factor signaling in prostate cancer Cancer Research. 70: 344-344. DOI: 10.1158/1538-7445.Am10-344  0.397
2010 Tien J, Liu Z, Liao L, Wang F, Xu J. Abstract 3245: SRC-3: A prostate cancer oncogene with the same modus operandi in different niches Cancer Research. 70: 3245-3245. DOI: 10.1158/1538-7445.Am10-3245  0.384
2010 McKeehan WL, Wang F, Luo Y. The fibroblast growth factor (fgf) signaling complex Handbook of Cell Signaling, 2/E. 1: 253-259. DOI: 10.1016/B978-0-12-374145-5.00038-3  0.468
2009 Cai Z, Shi Z, Sanchez A, Zhang T, Liu M, Yang J, Wang F, Zhang D. Transcriptional regulation of Tlr11 gene expression in epithelial cells. The Journal of Biological Chemistry. 284: 33088-96. PMID 19801549 DOI: 10.1074/Jbc.M109.050757  0.315
2009 Xuan JW, Bygrave M, Valiyeva F, Moussa M, Izawa JI, Bauman GS, Klibanov A, Wang F, Greenberg NM, Fenster A. Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer model. Molecular Imaging. 8: 209-20. PMID 19728975 DOI: 10.2310/7290.2009.00020  0.351
2009 Luo Y, Yang C, Jin C, Xie R, Wang F, McKeehan WL. Novel phosphotyrosine targets of FGFR2IIIb signaling. Cellular Signalling. 21: 1370-8. PMID 19410646 DOI: 10.1016/J.Cellsig.2009.04.004  0.59
2009 Lin Y, Chen L, Lin C, Luo Y, Tsai RYL, Wang F. Neuron-derived FGF9 is Essential for Scaffold Formation of Bergmann Radial Fibers and Migration of Granule Neurons in the Cerebellum Developmental Biology. 329: 44-54. PMID 19232523 DOI: 10.1016/J.Ydbio.2009.02.011  0.354
2009 Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Molecular Carcinogenesis. 48: 553-62. PMID 19009564 DOI: 10.1002/Mc.20494  0.589
2009 Lin Y, Cheng YS, Qin C, Lin C, D'Souza R, Wang F. FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 324-30. PMID 18985768 DOI: 10.1002/Dvdy.21778  0.359
2008 Zhang J, Lin Y, Zhang Y, Lan Y, Lin C, Moon AM, Schwartz RJ, Martin JF, Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development (Cambridge, England). 135: 3611-22. PMID 18832393 DOI: 10.1242/Dev.025361  0.398
2008 Lan Y, Zhang Y, Wang J, Lin C, Ittmann MM, Wang F. Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. International Journal of Cancer. 123: 543-551. PMID 18498131 DOI: 10.1002/Ijc.23548  0.416
2008 Sutherland BW, Knoblaugh SE, Kaplan-Lefko PJ, Wang F, Holzenberger M, Greenberg NM. Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium. Cancer Research. 68: 3495-504. PMID 18451178 DOI: 10.1158/0008-5472.Can-07-6531  0.41
2008 Zhang Y, Zhang J, Lin Y, Lan Y, Lin C, Xuan JW, Shen MM, McKeehan WL, Greenberg NM, Wang F. Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis. Development (Cambridge, England). 135: 775-84. PMID 18184727 DOI: 10.1242/Dev.009910  0.578
2008 Zhang Y, McKeehan K, Lin Y, Zhang J, Wang F. Fibroblast Growth Factor Receptor 1 (FGFR1) Tyrosine Phosphorylation Regulates Binding of FGFR Substrate 2α (FRS2α) But Not FRS2β to the Receptor Molecular Endocrinology. 22: 167-175. PMID 17901128 DOI: 10.1210/Me.2007-0140  0.364
2007 Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell. 12: 559-71. PMID 18068632 DOI: 10.1016/J.Ccr.2007.11.004  0.412
2007 Lin Y, Zhang J, Zhang Y, Wang F. Generation of an Fgf9 conditional null allele. Genesis. 45: 554-559. PMID 17868091 DOI: 10.1002/Dvg.20327  0.373
2007 Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL. FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. Diabetes. 56: 2501-10. PMID 17664243 DOI: 10.2337/Db07-0648  0.542
2007 Lin Y, Liu G, Zhang Y, Hu YP, Yu K, Lin C, McKeehan K, Xuan JW, Ornitz DM, Shen MM, Greenberg N, McKeehan WL, Wang F. Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis. Development (Cambridge, England). 134: 723-34. PMID 17215304 DOI: 10.1242/Dev.02765  0.551
2006 Huang X, Yu C, Jin C, Yang C, Xie R, Cao D, Wang F, McKeehan WL. Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis. Molecular Carcinogenesis. 45: 934-42. PMID 16929488 DOI: 10.1002/mc.20241  0.508
2006 Huang X, Yu C, Jin C, Kobayashi M, Bowles CA, Wang F, McKeehan WL. Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis. Cancer Research. 66: 1481-90. PMID 16452204 DOI: 10.1158/0008-5472.Can-05-2412  0.555
2006 Weng J, Wang J, Hu X, Wang F, Ittmann M, Liu M. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. International Journal of Cancer. 118: 1471-80. PMID 16206286 DOI: 10.1002/Ijc.21527  0.371
2005 Yu C, Wang F, Jin C, Huang X, McKeehan WL. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. The Journal of Biological Chemistry. 280: 17707-14. PMID 15750181 DOI: 10.1074/Jbc.M411771200  0.531
2004 Zhang Y, Lin Y, Bowles C, Wang F. Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2. The Journal of Biological Chemistry. 279: 55348-54. PMID 15513912 DOI: 10.1074/Jbc.M409230200  0.378
2004 Jin C, Wang F, Wu X, Yu C, Luo Y, McKeehan WL. Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors. Cancer Research. 64: 4555-62. PMID 15231666 DOI: 10.1158/0008-5472.Can-03-3752  0.606
2004 Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL. Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia. The Prostate. 58: 1-12. PMID 14673947 DOI: 10.1002/pros.10311  0.538
2003 Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F. Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Research. 63: 8784-90. PMID 14695195  0.492
2003 Yu C, Wang F, Jin C, Huang X, Miller DL, Basilico C, McKeehan WL. Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis. The American Journal of Pathology. 163: 1653-62. PMID 14507672 DOI: 10.1016/S0002-9440(10)63522-5  0.48
2003 Wu X, Jin C, Wang F, Yu C, McKeehan WL. Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors. Cancer Research. 63: 4936-44. PMID 12941818  0.542
2002 Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. The American Journal of Pathology. 161: 2003-10. PMID 12466116 DOI: 10.1016/S0002-9440(10)64478-1  0.425
2002 Wang F, McKeehan K, Yu C, McKeehan WL. Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy. Cancer Research. 62: 1898-903. PMID 11912171  0.53
2000 Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. The Journal of Biological Chemistry. 275: 15482-9. PMID 10809780 DOI: 10.1074/Jbc.275.20.15482  0.56
1999 Wang F, Lu W, McKeehan K, Mohamedali K, Gabriel JL, Kan M, McKeehan WL. Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex. Biochemistry. 38: 160-71. PMID 9890894 DOI: 10.1021/Bi981758M  0.52
1998 McKeehan WL, Wang F, Kan M. The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Progress in Nucleic Acid Research and Molecular Biology. 59: 135-76. PMID 9427842 DOI: 10.1016/S0079-6603(08)61031-4  0.566
1997 Jang JH, Wang F, Kan M. Heparan sulfate is required for interaction and activation of the epithelial cell fibroblast growth factor receptor-2IIIb with stromal-derived fibroblast growth factor-7 In Vitro Cellular & Developmental Biology – Animal. 33: 819-824. PMID 9466688 DOI: 10.1007/S11626-997-0162-7  0.438
1997 Wang F, Kan M, McKeehan K, Jang JH, Feng S, McKeehan WL. A homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor. The Journal of Biological Chemistry. 272: 23887-95. PMID 9295338 DOI: 10.1074/Jbc.272.38.23887  0.527
1996 Feng S, Xu J, Wang F, Kan M, McKeehan WL. Nuclear localization of a complex of fibroblast growth factor(FGF)-1 and an NH2-terminal fragment of FGF receptor isoforms R4 and R1alpha in human liver cells. Biochimica Et Biophysica Acta. 1310: 67-73. PMID 9244177 DOI: 10.1016/0167-4889(95)00146-8  0.533
1996 Luo Y, Gabriel JL, Wang F, Zhan X, Maciag T, Kan M, McKeehan WL. Molecular modeling and deletion mutagenesis implicate the nuclear translocation sequence in structural integrity of fibroblast growth factor-1. The Journal of Biological Chemistry. 271: 26876-83. PMID 8900171 DOI: 10.1074/Jbc.271.43.26876  0.534
1996 Kan M, Wang F, To B, Gabriel JL, McKeehan WL. Divalent cations and heparin/heparan sulfate cooperate to control assembly and activity of the fibroblast growth factor receptor complex. The Journal of Biological Chemistry. 271: 26143-8. PMID 8824259 DOI: 10.1074/Jbc.271.42.26143  0.539
1996 Wang F, McKeehan WL. Insulin-like growth factor-1 messenger RNA isoforms in rat prostate and prostate tumors. In Vitro Cellular & Developmental Biology. Animal. 32: 265-8. PMID 8792155 DOI: 10.1007/Bf02723058  0.508
1995 Wang F, Kan M, Yan G, Xu J, McKeehan WL. Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1. The Journal of Biological Chemistry. 270: 10231-5. PMID 7730327 DOI: 10.1074/Jbc.270.17.10231  0.52
1995 Wang F, Kan M, Xu J, Yan G, McKeehan WL. Ligand-specific structural domains in the fibroblast growth factor receptor Journal of Biological Chemistry. 270: 10222-10230. PMID 7730326 DOI: 10.1074/Jbc.270.17.10222  0.528
1994 Xu J, Matsuzaki K, Mckeehan K, Wang F, Kan M, Mckeehan WL. Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition Proceedings of the National Academy of Sciences of the United States of America. 91: 7957-7961. PMID 8058741 DOI: 10.1073/Pnas.91.17.7957  0.498
1994 Hou J, Wang F, McKeehan WL. Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2) In Vitro Cellular & Developmental Biology - Animal: Journal of the Society For in Vitro Biology. 30: 111-114. PMID 8012652 DOI: 10.1007/Bf02631402  0.461
1991 Yan G, Nikolaropoulos S, Wang F, McKeehan WL. Sequence of rat keratinocyte growth factor (heparin-binding growth factor type 7) [3] In Vitro Cellular and Developmental Biology - Animal. 27: 437-438. PMID 1869483 DOI: 10.1007/Bf02631140  0.416
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