Year |
Citation |
Score |
2022 |
Fan Z, Ma J, Pan X, Zhao L, Wu Y, Lin H, Zhao Y, Jiang H, Pan T, Li X, Wang F, Wang C. Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells. International Journal of Cancer. PMID 34985768 DOI: 10.1002/ijc.33922 |
0.323 |
|
2020 |
Wang F, Li X, Wang C. Editorial: Resident and Ectopic FGF Signaling in Development and Disease. Frontiers in Cell and Developmental Biology. 8: 720. PMID 32984306 DOI: 10.3389/Fcell.2020.00720 |
0.32 |
|
2020 |
Labanca E, Vazquez ES, Corn PG, Roberts JM, Wang F, Logothetis CJ, Navone NM. Fibroblast growth factors signaling in bone metastasis. Endocrine-Related Cancer. PMID 32369771 DOI: 10.1530/Erc-19-0472 |
0.332 |
|
2020 |
Jiang G, Liang X, Huang Y, Lan Z, Zhang Z, Su Z, Fang Z, Lai Y, Yao W, Liu T, Hu, Wang F, Huang H, Liu L, Jiang X. p62 promotes proliferation, apoptosis‑resistance and invasion of prostate cancer cells through the Keap1/Nrf2/ARE axis. Oncology Reports. PMID 32323805 DOI: 10.3892/Or.2020.7527 |
0.383 |
|
2020 |
Chen G, Cai ZD, Lin ZY, Wang C, Liang YX, Han ZD, He HC, Mo RJ, Lu JM, Pan B, Wu CL, Wang F, Zhong WD. ARNT-dependent CCR8 reprogrammed LDH isoform expression correlates with poor clinical outcomes of prostate cancer. Molecular Carcinogenesis. PMID 32319143 DOI: 10.1002/Mc.23201 |
0.394 |
|
2020 |
Li W, Dai Y, Shi B, Yue F, Zou J, Xu G, Jiang X, Wang F, Zhou X, Liu L. LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas. Oncogene. PMID 32203162 DOI: 10.1038/S41388-020-1257-9 |
0.327 |
|
2019 |
Riaz SK, Ke Y, Wang F, Kayani MA, Malik MFA. Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells. Scientific Reports. 9: 6620. PMID 31036836 DOI: 10.1038/S41598-019-43093-X |
0.317 |
|
2019 |
Wang C, Liu Z, Ke Y, Wang F. Intrinsic FGFR2 and Ectopic FGFR1 Signaling in the Prostate and Prostate Cancer. Frontiers in Genetics. 10: 12. PMID 30761180 DOI: 10.3389/Fgene.2019.00012 |
0.463 |
|
2019 |
Ji S, Liu Q, Zhang S, Chen Q, Wang C, Zhang W, Xiao C, Li Y, Nian C, Li J, Li J, Geng J, Hong L, Xie C, He Y, ... ... Wang F, et al. FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis. Developmental Cell. PMID 30745141 DOI: 10.1016/J.Devcel.2018.12.021 |
0.363 |
|
2019 |
Li H, Mao Y, Bouaziz M, Yu H, Qu X, Wang F, Feng GS, Shawber C, Zhang X. Lens differentiation is controlled by the balance between PDGF and FGF signaling. Plos Biology. 17: e3000133. PMID 30716082 DOI: 10.1371/Journal.Pbio.3000133 |
0.437 |
|
2018 |
Wang C, Ke Y, Liu S, Pan S, Liu Z, Zhang H, Fan Z, Zhou C, Liu J, Wang F. Ectopic fibroblast growth factor receptor 1 promotes inflammation by promoting nuclear factor-κB signaling in prostate cancer cells. The Journal of Biological Chemistry. PMID 30093411 DOI: 10.1074/Jbc.Ra118.002907 |
0.448 |
|
2018 |
Liu J, Chen G, Liu Z, Liu S, Cai Z, You P, Ke Y, Lai L, Huang Y, Gao H, Zhao L, Pelicano H, Huang P, McKeehan WL, Wu CL, ... ... Wang F, et al. Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer. Cancer Research. PMID 29891507 DOI: 10.1158/0008-5472.Can-17-3226 |
0.583 |
|
2018 |
Li Q, Alsaidan OA, Ma Y, Kim S, Liu J, Albers T, Liu K, Beharry Z, Zhao S, Wang F, Lebedyeva I, Cai H. Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression. The Journal of Biological Chemistry. PMID 29540482 DOI: 10.1074/Jbc.Ra117.000940 |
0.436 |
|
2018 |
Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 7. PMID 29360039 DOI: 10.7554/Elife.32586 |
0.391 |
|
2017 |
Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X. Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. Plos Genetics. 13: e1007047. PMID 29028795 DOI: 10.1371/Journal.Pgen.1007047 |
0.415 |
|
2017 |
Nandi S, Gutin G, Blackwood CA, Kamatkar NG, Lee KW, Fishell G, Wang F, Goldfarb M, Hébert JM. FGF-dependent, context-driven role for FRS adapters in the early telencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28483978 DOI: 10.1523/Jneurosci.2931-16.2017 |
0.387 |
|
2017 |
Lin H, Fang Z, Su Y, Li P, Wang J, Liao H, Hu Q, Ye C, Fang Y, Luo Q, Lin Z, Pan C, Wang F, Zhang ZY. DHX32 Promotes Angiogenesis in Colorectal Cancer Through Augmenting β-catenin Signaling to Induce Expression of VEGFA. Ebiomedicine. PMID 28330603 DOI: 10.1016/J.Ebiom.2017.03.012 |
0.325 |
|
2016 |
Mathew G, Hannan A, Hertzler-Schaefer K, Wang F, Feng GS, Zhong J, Zhao JJ, Downward J, Zhang X. Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799550 DOI: 10.1073/Pnas.1604450113 |
0.337 |
|
2016 |
Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. PMID 27374105 DOI: 10.18632/Oncotarget.10294 |
0.389 |
|
2016 |
Li X, Wang C, Xiao J, McKeehan WL, Wang F. Fibroblast growth factors, old kids on the new block. Seminars in Cell & Developmental Biology. PMID 26768548 DOI: 10.1016/J.Semcdb.2015.12.014 |
0.585 |
|
2016 |
Li W, Zou J, Yue F, Song K, Chen Q, McKeehan WL, Wang F, Xu G, Huang H, Yi J, Liu L. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. PMID 26750654 DOI: 10.1111/Acel.12441 |
0.487 |
|
2015 |
Shi M, Zhang Y, Liu L, Zhang T, Han F, Cleveland J, Wang F, McKeehan WL, Li Y, Zhang D. MAP1S regulates the phagocytosis of bacteria and TLR signaling. The Journal of Biological Chemistry. PMID 26565030 DOI: 10.1074/Jbc.M115.687376 |
0.411 |
|
2015 |
Yue F, Li W, Zou J, Chen Q, Xu G, Huang H, Xu Z, Zhang S, Gallinari P, Wang F, McKeehan WL, Liu L. Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin. Aging. 7: 839-853. PMID 26540094 |
0.383 |
|
2015 |
Lin L, Fang Z, Lin H, You H, Wang J, Su Y, Wang F, Zhang ZY. Depletion of Cks1 and Cks2 expression compromises cell proliferation and enhance chemotherapy-induced apoptosis in HepG2 cells. Oncology Reports. PMID 26531156 DOI: 10.3892/Or.2015.4372 |
0.35 |
|
2015 |
Huang Y, Jin C, Hamana T, Liu J, Wang C, An L, McKeehan WL, Wang F. Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression. International Journal of Biological Sciences. 11: 948-60. PMID 26157349 DOI: 10.7150/Ijbs.12468 |
0.586 |
|
2015 |
Liu J, You P, Chen G, Fu X, Zeng X, Wang C, Huang Y, An L, Wan X, Navone N, Wu CL, McKeehan WL, Zhang Z, Zhong W, Wang F. Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients. Oncogene. PMID 26096936 DOI: 10.1038/Onc.2015.239 |
0.591 |
|
2015 |
Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, McKeehan WL, Wang F. Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment. The Journal of Biological Chemistry. 290: 17745-52. PMID 26032419 DOI: 10.1074/Jbc.M115.661033 |
0.533 |
|
2015 |
Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, Jin C, Zhang Z, McKeehan WL, Wang F. Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment. The Journal of Biological Chemistry. 290: 17753-61. PMID 26032417 DOI: 10.1074/Jbc.M115.661066 |
0.546 |
|
2015 |
Ho TH, Liu XD, Huang Y, Warneke CL, Johnson MM, Hoang A, Tamboli P, Wang F, Jonasch E. The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma. Bmc Cancer. 15: 304. PMID 25900027 DOI: 10.1186/S12885-015-1302-1 |
0.376 |
|
2015 |
Lin H, Liu W, Fang Z, Liang X, Li J, Bai Y, Lin L, You H, Pei Y, Wang F, Zhang ZY. Overexpression of DHX32 contributes to the growth and metastasis of colorectal cancer. Scientific Reports. 5: 9247. PMID 25782664 DOI: 10.1038/Srep09247 |
0.312 |
|
2015 |
Xu C, Li W, Qiu P, Xia Y, Du X, Wang F, Shen L, Chen Q, Zhao Y, Jin R, Wu J, Liang G, Li X. The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. Anti-Cancer Drugs. 26: 379-87. PMID 25521558 DOI: 10.1097/Cad.0000000000000195 |
0.327 |
|
2015 |
Wang F, Luo Y, McKeehan WL. The FGF signaling axis in prostate tumorigenesis Molecular Oncology: Causes of Cancer and Targets For Treatment. 190-203. DOI: 10.1017/CBO9781139046947.017 |
0.488 |
|
2014 |
Tien JC, Liao L, Liu Y, Liu Z, Lee DK, Wang F, Xu J. The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. International Journal of Biological Sciences. 10: 1116-27. PMID 25332686 DOI: 10.7150/Ijbs.10236 |
0.408 |
|
2014 |
Wan X, Corn PG, Yang J, Palanisamy N, Starbuck MW, Efstathiou E, Tapia EM, Tapia EM, Zurita AJ, Aparicio A, Ravoori MK, Vazquez ES, Robinson DR, Wu YM, Cao X, ... ... Wang F, et al. Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases. Science Translational Medicine. 6: 252ra122. PMID 25186177 DOI: 10.1126/Scitranslmed.3009332 |
0.539 |
|
2014 |
Zhao S, Zhang Y, Zhang Q, Wang F, Zhang D. Toll-like receptors and prostate cancer. Frontiers in Immunology. 5: 352. PMID 25101092 DOI: 10.3389/Fimmu.2014.00352 |
0.337 |
|
2014 |
Wang C, Yang C, Chang JY, You P, Li Y, Jin C, Luo Y, Li X, McKeehan WL, Wang F. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity. Current Molecular Medicine. 14: 703-11. PMID 25056539 DOI: 10.2174/1566524014666140724095112 |
0.57 |
|
2014 |
Jiang X, Zhong W, Huang H, He H, Jiang F, Chen Y, Yue F, Zou J, Li X, He Y, You P, Yang W, Lai Y, Wang F, Liu L. Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients. Molecular Carcinogenesis. PMID 25043940 DOI: 10.1002/Mc.22193 |
0.321 |
|
2014 |
Yin Y, Wang H, Liu K, Wang F, Ye X, Liu M, Xiang R, Liu N, Liu L. Knockdown of H19 enhances differentiation capacity to epidermis of parthenogenetic embryonic stem cells. Current Molecular Medicine. 14: 737-748. PMID 24894171 DOI: 10.2174/1566524014666140724101035 |
0.308 |
|
2014 |
Jiang X, Li X, Huang H, Jiang F, Lin Z, He H, Chen Y, Yue F, Zou J, He Y, You P, Wang W, Yang W, Zhao H, Lai Y, ... Wang F, et al. Elevated levels of mitochondrion-associated autophagy inhibitor LRPPRC are associated with poor prognosis in patients with prostate cancer. Cancer. 120: 1228-36. PMID 24390809 DOI: 10.1002/Cncr.28551 |
0.341 |
|
2014 |
Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X. Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development. Journal of Cell Science. 127: 571-82. PMID 24284065 DOI: 10.1242/Jcs.134478 |
0.38 |
|
2013 |
Warneke CL, Hoang A, Tamboli P, Wang F, Jonasch E. The role of FGF signaling in VEGF-pathway targeted therapy resistance: Data from patients and model systems. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 386. PMID 28136881 DOI: 10.1200/Jco.2013.31.6_Suppl.386 |
0.358 |
|
2013 |
Yang Z, Hai B, Qin L, Ti X, Shangguan L, Zhao Y, Wiggins L, Liu Y, Feng JQ, Chang JY, Wang F, Liu F. Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner. Molecular and Cellular Biology. 33: 4732-44. PMID 24081330 DOI: 10.1128/Mcb.00456-13 |
0.332 |
|
2013 |
Corn PG, Wang F, McKeehan WL, Navone N. Targeting fibroblast growth factor pathways in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5856-66. PMID 24052019 DOI: 10.1158/1078-0432.Ccr-13-1550 |
0.575 |
|
2013 |
Chang JY, Wang C, Liu J, Huang Y, Jin C, Yang C, Hai B, Liu F, D'Souza RN, McKeehan WL, Wang F. Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells. The Journal of Biological Chemistry. 288: 28952-61. PMID 23979135 DOI: 10.1074/Jbc.M113.506873 |
0.568 |
|
2013 |
Chang JY, Wang C, Jin C, Yang C, Huang Y, Liu J, McKeehan WL, D'Souza RN, Wang F. Self-renewal and multilineage differentiation of mouse dental epithelial stem cells. Stem Cell Research. 11: 990-1002. PMID 23906788 DOI: 10.1016/J.Scr.2013.06.008 |
0.526 |
|
2013 |
Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li X. Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. The Journal of Biological Chemistry. 288: 22174-83. PMID 23754280 DOI: 10.1074/Jbc.M113.463620 |
0.575 |
|
2013 |
Gay D, Kwon O, Zhang Z, Spata M, Plikus MV, Holler PD, Ito M, Yang Z, Treffeisen E, Kim CD, Nace A, Zhang X, Baratono S, Wang F, Ornitz DM, et al. Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding. Nature Medicine. 19: 916-23. PMID 23727932 DOI: 10.1038/Nm.3181 |
0.342 |
|
2013 |
Cai Z, Tao C, Li H, Ladher R, Gotoh N, Feng GS, Wang F, Zhang X. Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma. Development (Cambridge, England). 140: 2711-23. PMID 23720040 DOI: 10.1242/Dev.089987 |
0.333 |
|
2013 |
Tien JC, Liu Z, Liao L, Wang F, Xu Y, Wu YL, Zhou N, Ittmann M, Xu J. The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer. Cancer Research. 73: 3997-4008. PMID 23650284 DOI: 10.1158/0008-5472.Can-12-3929 |
0.421 |
|
2013 |
Yang C, Lu W, Lin T, You P, Ye M, Huang Y, Jiang X, Wang C, Wang F, Lee MH, Yeung SC, Johnson RL, Wei C, Tsai RY, Frazier ML, et al. Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress. Bmc Gastroenterology. 13: 67. PMID 23590285 DOI: 10.1186/1471-230X-13-67 |
0.486 |
|
2013 |
Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR. FGFR1 is essential for prostate cancer progression and metastasis. Cancer Research. 73: 3716-24. PMID 23576558 DOI: 10.1158/0008-5472.Can-12-3274 |
0.421 |
|
2013 |
Guan JL, Simon AK, Prescott M, Menendez JA, Liu F, Wang F, Wang C, Wolvetang E, Vazquez-Martin A, Zhang J. Autophagy in stem cells. Autophagy. 9: 830-49. PMID 23486312 DOI: 10.4161/Auto.24132 |
0.325 |
|
2013 |
Zhang T, Liu J, Zhang J, Thekkethottiyil EB, Macatee TL, Ismat FA, Wang F, Stoller JZ. Jun is required in Isl1-expressing progenitor cells for cardiovascular development. Plos One. 8: e57032. PMID 23437302 DOI: 10.1371/Journal.Pone.0057032 |
0.323 |
|
2013 |
Wan X, Corn P, Yang J, Efstathiou E, Tapia EMLN, Wang F, McKeehan W, Logothetis C, Troncoso P, Navone NM. Abstract 2436: Fibroblast growth factor receptor blockade in prostate cancer bone metastases. Cancer Research. 73: 2436-2436. DOI: 10.1158/1538-7445.Am2013-2436 |
0.543 |
|
2012 |
Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, Gupte J, Komorowski R, Sekirov L, Hager T, Arora T, ... ... Wang F, et al. Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex. Science Translational Medicine. 4: 162ra153. PMID 23197570 DOI: 10.1126/Scitranslmed.3004690 |
0.515 |
|
2012 |
Madakashira BP, Kobrinski DA, Hancher AD, Arneman EC, Wagner BD, Wang F, Shin H, Lovicu FJ, Reneker LW, Robinson ML. Frs2α enhances fibroblast growth factor-mediated survival and differentiation in lens development. Development (Cambridge, England). 139: 4601-12. PMID 23136392 DOI: 10.1242/Dev.081737 |
0.396 |
|
2012 |
Yang C, Wang C, Ye M, Jin C, He W, Wang F, McKeehan WL, Luo Y. Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress. Nutrition & Metabolism. 9: 94. PMID 23106963 DOI: 10.1186/1743-7075-9-94 |
0.522 |
|
2012 |
Zhou J, Qin L, Tien JC, Gao L, Chen X, Wang F, Hsieh JT, Xu J. Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner. The Journal of Biological Chemistry. 287: 17248-56. PMID 22465996 DOI: 10.1074/Jbc.M111.336909 |
0.406 |
|
2012 |
Yang C, Jin C, Li X, Wang F, McKeehan WL, Luo Y. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB. Plos One. 7: e33870. PMID 22442730 DOI: 10.1371/Journal.Pone.0033870 |
0.529 |
|
2012 |
Zhang J, Liu J, Liu L, McKeehan WL, Wang F. The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy. Autophagy. 8: 690-1. PMID 22302007 DOI: 10.4161/Auto.19290 |
0.555 |
|
2012 |
Liu L, McKeehan WL, Wang F, Xie R. MAP1S enhances autophagy to suppress tumorigenesis. Autophagy. 8: 278-80. PMID 22301994 DOI: 10.4161/Auto.8.2.18939 |
0.456 |
|
2012 |
Yang X, Li Q, Lin X, Ma Y, Yue X, Tao Z, Wang F, Mckeehan WL, Wei L, Schwartz RJ, Chang J. Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2105-16. PMID 22278938 DOI: 10.1096/Fj.11-201319 |
0.511 |
|
2012 |
Zhang J, Liu J, Huang Y, Chang JY, Liu L, McKeehan WL, Martin JF, Wang F. FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity. Circulation Research. 110: e29-39. PMID 22207710 DOI: 10.1161/Circresaha.111.255950 |
0.568 |
|
2011 |
Ho TH, Wang F, Hoang A, Tamboli P, Jonasch E. Fibroblast growth factor receptor 1 (FGFR1) expression and activation in clear cell renal cell carcinoma (ccRCC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e15015. PMID 28020567 DOI: 10.1200/Jco.2011.29.15_Suppl.E15015 |
0.391 |
|
2011 |
Xie R, Wang F, McKeehan WL, Liu L. Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. Cancer Research. 71: 7537-46. PMID 22037873 DOI: 10.1158/0008-5472.Can-11-2170 |
0.454 |
|
2011 |
Lin X, Zhang Y, Liu L, McKeehan WL, Shen Y, Song S, Wang F. FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts. International Journal of Biological Sciences. 7: 1114-21. PMID 21927580 DOI: 10.7150/Ijbs.7.1114 |
0.573 |
|
2011 |
Yin Y, Wang F, Ornitz DM. Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development. Development (Cambridge, England). 138: 3169-77. PMID 21750028 DOI: 10.1242/Dev.065110 |
0.375 |
|
2011 |
Jin C, Yang C, Wu X, Wang F, McKeehan WL. FGFR3-expressing smooth muscle-like stromal cells differentiate in response to FGFR2IIIb-expressing prostate tumor cells and delay tumor progression. In Vitro Cellular & Developmental Biology. Animal. 47: 500-5. PMID 21691921 DOI: 10.1007/S11626-011-9432-5 |
0.543 |
|
2011 |
Valiyeva F, Jiang F, Elmaadawi A, Moussa M, Yee SP, Raptis L, Izawa JI, Yang BB, Greenberg NM, Wang F, Xuan JW. Characterization of the oncogenic activity of the novel TRIM59 gene in mouse cancer models. Molecular Cancer Therapeutics. 10: 1229-40. PMID 21593385 DOI: 10.1158/1535-7163.Mct-11-0077 |
0.394 |
|
2011 |
Kobayashi M, Huang Y, Jin C, Luo Y, Okamoto T, Wang F, McKeehan WL. FGFR1 abrogates inhibitory effect of androgen receptor concurrent with induction of androgen-receptor variants in androgen receptor-negative prostate tumor epithelial cells. The Prostate. 71: 1691-700. PMID 21446013 DOI: 10.1002/Pros.21386 |
0.521 |
|
2011 |
Wang F. Modeling human prostate cancer in genetically engineered mice Progress in Molecular Biology and Translational Science. 100: 1-49. PMID 21377623 DOI: 10.1016/B978-0-12-384878-9.00001-7 |
0.335 |
|
2011 |
Xie R, Nguyen S, McKeehan K, Wang F, McKeehan WL, Liu L. Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. The Journal of Biological Chemistry. 286: 10367-77. PMID 21262964 DOI: 10.1074/Jbc.M110.206532 |
0.458 |
|
2011 |
Wang F, McKeehan WL, Shen MM, Abate-Shen C. Genetically engineered mouse models in prostate cancer research Recent Advances in Prostate Cancer: Basic Science Discoveries and Clinical Advances. 219-282. DOI: 10.1142/9789814329460_0009 |
0.624 |
|
2010 |
Zhang J, Chang JY, Huang Y, Lin X, Luo Y, Schwartz RJ, Martin JF, Wang F. The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circulation Research. 107: 1209-19. PMID 20847311 DOI: 10.1161/Circresaha.110.225318 |
0.348 |
|
2010 |
Luo Y, Yang C, Lu W, Xie R, Jin C, Huang P, Wang F, McKeehan WL. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. The Journal of Biological Chemistry. 285: 30069-78. PMID 20657013 DOI: 10.1074/Jbc.M110.148288 |
0.593 |
|
2010 |
Zhang L, Zhang B, Valdez JM, Wang F, Ittmann M, Xin L. Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells (Dayton, Ohio). 28: 1260-9. PMID 20517984 DOI: 10.1002/Stem.455 |
0.39 |
|
2010 |
Lin Y, Wang F. FGF signalling in prostate development, tissue homoeostasis and tumorigenesis. Bioscience Reports. 30: 285-91. PMID 20406196 DOI: 10.1042/BSR20100020 |
0.321 |
|
2010 |
Wan X, Yang J, Starbuck MW, Ravoori MK, Lu J, Kundra V, Maity S, Wang F, Navone NM. Abstract 344: Targeting fibroblast growth factor signaling in prostate cancer Cancer Research. 70: 344-344. DOI: 10.1158/1538-7445.Am10-344 |
0.397 |
|
2010 |
Tien J, Liu Z, Liao L, Wang F, Xu J. Abstract 3245: SRC-3: A prostate cancer oncogene with the same modus operandi in different niches Cancer Research. 70: 3245-3245. DOI: 10.1158/1538-7445.Am10-3245 |
0.384 |
|
2010 |
McKeehan WL, Wang F, Luo Y. The fibroblast growth factor (fgf) signaling complex Handbook of Cell Signaling, 2/E. 1: 253-259. DOI: 10.1016/B978-0-12-374145-5.00038-3 |
0.468 |
|
2009 |
Cai Z, Shi Z, Sanchez A, Zhang T, Liu M, Yang J, Wang F, Zhang D. Transcriptional regulation of Tlr11 gene expression in epithelial cells. The Journal of Biological Chemistry. 284: 33088-96. PMID 19801549 DOI: 10.1074/Jbc.M109.050757 |
0.315 |
|
2009 |
Xuan JW, Bygrave M, Valiyeva F, Moussa M, Izawa JI, Bauman GS, Klibanov A, Wang F, Greenberg NM, Fenster A. Molecular targeted enhanced ultrasound imaging of flk1 reveals diagnosis and prognosis potential in a genetically engineered mouse prostate cancer model. Molecular Imaging. 8: 209-20. PMID 19728975 DOI: 10.2310/7290.2009.00020 |
0.351 |
|
2009 |
Luo Y, Yang C, Jin C, Xie R, Wang F, McKeehan WL. Novel phosphotyrosine targets of FGFR2IIIb signaling. Cellular Signalling. 21: 1370-8. PMID 19410646 DOI: 10.1016/J.Cellsig.2009.04.004 |
0.59 |
|
2009 |
Lin Y, Chen L, Lin C, Luo Y, Tsai RYL, Wang F. Neuron-derived FGF9 is Essential for Scaffold Formation of Bergmann Radial Fibers and Migration of Granule Neurons in the Cerebellum Developmental Biology. 329: 44-54. PMID 19232523 DOI: 10.1016/J.Ydbio.2009.02.011 |
0.354 |
|
2009 |
Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Molecular Carcinogenesis. 48: 553-62. PMID 19009564 DOI: 10.1002/Mc.20494 |
0.589 |
|
2009 |
Lin Y, Cheng YS, Qin C, Lin C, D'Souza R, Wang F. FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 324-30. PMID 18985768 DOI: 10.1002/Dvdy.21778 |
0.359 |
|
2008 |
Zhang J, Lin Y, Zhang Y, Lan Y, Lin C, Moon AM, Schwartz RJ, Martin JF, Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development (Cambridge, England). 135: 3611-22. PMID 18832393 DOI: 10.1242/Dev.025361 |
0.398 |
|
2008 |
Lan Y, Zhang Y, Wang J, Lin C, Ittmann MM, Wang F. Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. International Journal of Cancer. 123: 543-551. PMID 18498131 DOI: 10.1002/Ijc.23548 |
0.416 |
|
2008 |
Sutherland BW, Knoblaugh SE, Kaplan-Lefko PJ, Wang F, Holzenberger M, Greenberg NM. Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium. Cancer Research. 68: 3495-504. PMID 18451178 DOI: 10.1158/0008-5472.Can-07-6531 |
0.41 |
|
2008 |
Zhang Y, Zhang J, Lin Y, Lan Y, Lin C, Xuan JW, Shen MM, McKeehan WL, Greenberg NM, Wang F. Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis. Development (Cambridge, England). 135: 775-84. PMID 18184727 DOI: 10.1242/Dev.009910 |
0.578 |
|
2008 |
Zhang Y, McKeehan K, Lin Y, Zhang J, Wang F. Fibroblast Growth Factor Receptor 1 (FGFR1) Tyrosine Phosphorylation Regulates Binding of FGFR Substrate 2α (FRS2α) But Not FRS2β to the Receptor Molecular Endocrinology. 22: 167-175. PMID 17901128 DOI: 10.1210/Me.2007-0140 |
0.364 |
|
2007 |
Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell. 12: 559-71. PMID 18068632 DOI: 10.1016/J.Ccr.2007.11.004 |
0.412 |
|
2007 |
Lin Y, Zhang J, Zhang Y, Wang F. Generation of an Fgf9 conditional null allele. Genesis. 45: 554-559. PMID 17868091 DOI: 10.1002/Dvg.20327 |
0.373 |
|
2007 |
Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL. FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. Diabetes. 56: 2501-10. PMID 17664243 DOI: 10.2337/Db07-0648 |
0.542 |
|
2007 |
Lin Y, Liu G, Zhang Y, Hu YP, Yu K, Lin C, McKeehan K, Xuan JW, Ornitz DM, Shen MM, Greenberg N, McKeehan WL, Wang F. Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis. Development (Cambridge, England). 134: 723-34. PMID 17215304 DOI: 10.1242/Dev.02765 |
0.551 |
|
2006 |
Huang X, Yu C, Jin C, Yang C, Xie R, Cao D, Wang F, McKeehan WL. Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis. Molecular Carcinogenesis. 45: 934-42. PMID 16929488 DOI: 10.1002/mc.20241 |
0.508 |
|
2006 |
Huang X, Yu C, Jin C, Kobayashi M, Bowles CA, Wang F, McKeehan WL. Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis. Cancer Research. 66: 1481-90. PMID 16452204 DOI: 10.1158/0008-5472.Can-05-2412 |
0.555 |
|
2006 |
Weng J, Wang J, Hu X, Wang F, Ittmann M, Liu M. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. International Journal of Cancer. 118: 1471-80. PMID 16206286 DOI: 10.1002/Ijc.21527 |
0.371 |
|
2005 |
Yu C, Wang F, Jin C, Huang X, McKeehan WL. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. The Journal of Biological Chemistry. 280: 17707-14. PMID 15750181 DOI: 10.1074/Jbc.M411771200 |
0.531 |
|
2004 |
Zhang Y, Lin Y, Bowles C, Wang F. Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2. The Journal of Biological Chemistry. 279: 55348-54. PMID 15513912 DOI: 10.1074/Jbc.M409230200 |
0.378 |
|
2004 |
Jin C, Wang F, Wu X, Yu C, Luo Y, McKeehan WL. Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors. Cancer Research. 64: 4555-62. PMID 15231666 DOI: 10.1158/0008-5472.Can-03-3752 |
0.606 |
|
2004 |
Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL. Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia. The Prostate. 58: 1-12. PMID 14673947 DOI: 10.1002/pros.10311 |
0.538 |
|
2003 |
Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F. Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Research. 63: 8784-90. PMID 14695195 |
0.492 |
|
2003 |
Yu C, Wang F, Jin C, Huang X, Miller DL, Basilico C, McKeehan WL. Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis. The American Journal of Pathology. 163: 1653-62. PMID 14507672 DOI: 10.1016/S0002-9440(10)63522-5 |
0.48 |
|
2003 |
Wu X, Jin C, Wang F, Yu C, McKeehan WL. Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors. Cancer Research. 63: 4936-44. PMID 12941818 |
0.542 |
|
2002 |
Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. The American Journal of Pathology. 161: 2003-10. PMID 12466116 DOI: 10.1016/S0002-9440(10)64478-1 |
0.425 |
|
2002 |
Wang F, McKeehan K, Yu C, McKeehan WL. Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy. Cancer Research. 62: 1898-903. PMID 11912171 |
0.53 |
|
2000 |
Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. The Journal of Biological Chemistry. 275: 15482-9. PMID 10809780 DOI: 10.1074/Jbc.275.20.15482 |
0.56 |
|
1999 |
Wang F, Lu W, McKeehan K, Mohamedali K, Gabriel JL, Kan M, McKeehan WL. Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex. Biochemistry. 38: 160-71. PMID 9890894 DOI: 10.1021/Bi981758M |
0.52 |
|
1998 |
McKeehan WL, Wang F, Kan M. The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Progress in Nucleic Acid Research and Molecular Biology. 59: 135-76. PMID 9427842 DOI: 10.1016/S0079-6603(08)61031-4 |
0.566 |
|
1997 |
Jang JH, Wang F, Kan M. Heparan sulfate is required for interaction and activation of the epithelial cell fibroblast growth factor receptor-2IIIb with stromal-derived fibroblast growth factor-7 In Vitro Cellular & Developmental Biology – Animal. 33: 819-824. PMID 9466688 DOI: 10.1007/S11626-997-0162-7 |
0.438 |
|
1997 |
Wang F, Kan M, McKeehan K, Jang JH, Feng S, McKeehan WL. A homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor. The Journal of Biological Chemistry. 272: 23887-95. PMID 9295338 DOI: 10.1074/Jbc.272.38.23887 |
0.527 |
|
1996 |
Feng S, Xu J, Wang F, Kan M, McKeehan WL. Nuclear localization of a complex of fibroblast growth factor(FGF)-1 and an NH2-terminal fragment of FGF receptor isoforms R4 and R1alpha in human liver cells. Biochimica Et Biophysica Acta. 1310: 67-73. PMID 9244177 DOI: 10.1016/0167-4889(95)00146-8 |
0.533 |
|
1996 |
Luo Y, Gabriel JL, Wang F, Zhan X, Maciag T, Kan M, McKeehan WL. Molecular modeling and deletion mutagenesis implicate the nuclear translocation sequence in structural integrity of fibroblast growth factor-1. The Journal of Biological Chemistry. 271: 26876-83. PMID 8900171 DOI: 10.1074/Jbc.271.43.26876 |
0.534 |
|
1996 |
Kan M, Wang F, To B, Gabriel JL, McKeehan WL. Divalent cations and heparin/heparan sulfate cooperate to control assembly and activity of the fibroblast growth factor receptor complex. The Journal of Biological Chemistry. 271: 26143-8. PMID 8824259 DOI: 10.1074/Jbc.271.42.26143 |
0.539 |
|
1996 |
Wang F, McKeehan WL. Insulin-like growth factor-1 messenger RNA isoforms in rat prostate and prostate tumors. In Vitro Cellular & Developmental Biology. Animal. 32: 265-8. PMID 8792155 DOI: 10.1007/Bf02723058 |
0.508 |
|
1995 |
Wang F, Kan M, Yan G, Xu J, McKeehan WL. Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1. The Journal of Biological Chemistry. 270: 10231-5. PMID 7730327 DOI: 10.1074/Jbc.270.17.10231 |
0.52 |
|
1995 |
Wang F, Kan M, Xu J, Yan G, McKeehan WL. Ligand-specific structural domains in the fibroblast growth factor receptor Journal of Biological Chemistry. 270: 10222-10230. PMID 7730326 DOI: 10.1074/Jbc.270.17.10222 |
0.528 |
|
1994 |
Xu J, Matsuzaki K, Mckeehan K, Wang F, Kan M, Mckeehan WL. Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition Proceedings of the National Academy of Sciences of the United States of America. 91: 7957-7961. PMID 8058741 DOI: 10.1073/Pnas.91.17.7957 |
0.498 |
|
1994 |
Hou J, Wang F, McKeehan WL. Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2) In Vitro Cellular & Developmental Biology - Animal: Journal of the Society For in Vitro Biology. 30: 111-114. PMID 8012652 DOI: 10.1007/Bf02631402 |
0.461 |
|
1991 |
Yan G, Nikolaropoulos S, Wang F, McKeehan WL. Sequence of rat keratinocyte growth factor (heparin-binding growth factor type 7) [3] In Vitro Cellular and Developmental Biology - Animal. 27: 437-438. PMID 1869483 DOI: 10.1007/Bf02631140 |
0.416 |
|
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