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Sofiia Karchugina - Publications

Affiliations: 
2017- Pirogov Russian National Research Medical University 
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chow HY, Karchugina S, Groendyke BJ, Toenjes S, Hatcher J, Donovan KA, Fischer ES, Abalakov G, Faezov B, Dunbrack R, Gray NS, Chernoff J. Development and Utility of a PAK1-Selective Degrader. Journal of Medicinal Chemistry. 65: 15627-15641. PMID 36416208 DOI: 10.1021/acs.jmedchem.2c00756  0.572
2022 Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling. Molecular Cancer Research : McR. PMID 35082167 DOI: 10.1158/1541-7786.MCR-21-0837  0.637
2021 Hawley E, Gehlhausen J, Karchugina S, Chow HY, Araiza-Olivera D, Radu M, Smith A, Burks C, Jiang L, Li X, Bessler W, Masters A, Edwards D, Burgin C, Jones D, et al. PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2). Human Molecular Genetics. PMID 34075397 DOI: 10.1093/hmg/ddab106  0.607
2021 Karchugina S, Benton D, Chernoff J. Regulation of MST complexes and activity via SARAH domain modifications. Biochemical Society Transactions. 49: 675-683. PMID 33860801 DOI: 10.1042/BST20200559  0.582
2019 Shen YC, Arellano-Garcia C, Menjivar RE, Jewett EM, Dohle W, Karchugina S, Chernoff J, Potter BVL, Barald KF. Nonsteroidal sulfamate derivatives as new therapeutic approaches for Neurofibromatosis 2 (NF2). Bmc Pharmacology & Toxicology. 20: 67. PMID 31730023 DOI: 10.1186/S40360-019-0369-8  0.595
2018 Karchugina S, Chernoff J. Detection of Heterodimerization of Protein Isoforms Using an in Situ Proximity Ligation Assay. Journal of Visualized Experiments : Jove. PMID 30394375 DOI: 10.3791/57755  0.534
2018 Semenova G, Stepanova D, Karchugina S, Dubyk C, Deyev S, Lazar A, Chernoff J. Abstract B066: Unique roles of group I PAK isoforms in regulating MPNST cell viability Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B066  0.432
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