James West - Publications

Affiliations: 
Chemistry College of Wooster 

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Liu B, Azfar M, Legchenko E, West JA, Martin S, Van den Haute C, Baekelandt V, Wharton J, Howard L, Wilkins MR, Vangheluwe P, Morrell NW, Upton PD. ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport. Cardiovascular Research. PMID 38626311 DOI: 10.1093/cvr/cvae068  0.315
2023 Talati M, Brittain E, Agrawal V, Fortune N, Simon K, Shay S, Zeng X, Freeman ML, West J, Hemnes A. A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific. Frontiers in Medicine. 10: 1276422. PMID 37869164 DOI: 10.3389/fmed.2023.1276422  0.317
2022 Suzuki T, Kropski JA, Chen J, Carrier EJ, Chen X, Sherrill TP, Winters NI, Camarata JE, Polosukhin VV, Han W, Rathinasabapathy A, Gutor S, Gulleman P, Sabusap C, Banovich NE, ... ... West JD, et al. Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 35728047 DOI: 10.1164/rccm.202106-1503OC  0.3
2021 West J, Rathinasabapathy A, Chen X, Shay S, Gladson S, Talati M. Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury. Cells. 10. PMID 34571956 DOI: 10.3390/cells10092306  0.39
2021 West JD, Austin ED, Rizzi EM, Yan L, Tanjore H, Crabtree AL, Moore CS, Muthian G, Carrier EJ, Jacobson DA, Hamid R, Kendall PL, Majka S, Rathinasabapathy A. KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models. International Journal of Molecular Sciences. 22. PMID 34065088 DOI: 10.3390/ijms22095014  0.327
2020 Halliday SJ, Matthews DT, Talati MH, Austin ED, Su YR, Absi TS, Fortune NL, Gailani D, Matafonov A, West JD, Hemnes AR. A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis. Jrsm Cardiovascular Disease. 9: 2048004020906994. PMID 32110389 DOI: 10.1177/2048004020906994  0.324
2019 Agrawal V, Fortune N, Yu S, Fuentes J, Shi F, Nichols D, Gleaves L, Poovey E, Wang TJ, Brittain EL, Collins S, West JD, Hemnes AR. Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension. Pulmonary Circulation. 9: 2045894019878599. PMID 31903184 DOI: 10.1177/2045894019895452  0.3
2019 West JD, Chen X, Ping L, Gladson S, Hamid R, Lloyd JE, Talati M. Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension. Pulmonary Circulation. 2045894019856483. PMID 31124398 DOI: 10.1177/2045894019856483  0.45
2019 Nickel N, Perez VAJ, Fessel JP, Cogan J, Hamid R, West JD, de Caestecker M, Yang H, Zamanian RT, Austin E. EXPRESS: Low-Grade Albuminuria in Pulmonary Arterial Hypertension. Pulmonary Circulation. 2045894018824564. PMID 30632900 DOI: 10.1177/2045894018824564  0.315
2019 Hemnes AR, Luther JM, Rhodes CJ, Burgess JP, Carlson J, Fan R, Fessel JP, Fortune N, Gerszten RE, Halliday SJ, Hekmat R, Howard L, Newman JH, Niswender KD, Pugh ME, ... ... West J, et al. Human PAH is characterized by a pattern of lipid-related insulin resistance. Jci Insight. 4. PMID 30626738 DOI: 10.1172/Jci.Insight.123611  0.323
2019 Kamely M, Karimi Torshizi MA, Wideman RF, West J. Upregulation of SERT and ADORA1 in broilers with acute right ventricular failure. Research in Veterinary Science. 125: 397-400. PMID 29174607 DOI: 10.1016/J.Rvsc.2017.09.030  0.378
2018 Bloodworth NC, Clark CR, West JD, Snider JC, Gaskill C, Shay S, Scott C, Bastarache J, Gladson S, Moore C, D'Amico R, Brittain EL, Tanjore H, Blackwell TS, Majka SM, et al. Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism. Circulation Research. 123: e51-e64. PMID 30566041 DOI: 10.1161/Circresaha.118.313397  0.353
2018 Bryant A, Fu C, Lu Y, Brantly M, Moldawer L, Brusko T, Brittain E, West JD, Austin E, Hamid R. EXPRESS: A Checkpoint on Innate Myeloid Cells in Pulmonary Arterial Hypertension. Pulmonary Circulation. 2045894018823528. PMID 30562157 DOI: 10.1177/2045894018823528  0.344
2018 Brittain E, Talati M, Penner N, Agrawal V, Meoli DF, West JD, Hemnes A. EXPRESS: Adverse Physiologic Effects of Western Diet on Right Ventricular Structure and Function: Role of Lipid Accumulation and Metabolic Therapy. Pulmonary Circulation. 2045894018817741. PMID 30451070 DOI: 10.1177/2045894018817741  0.331
2018 D'Amico RW, Faley S, Shim HN, Prosser JR, Agrawal V, Bellan LM, West JD. Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in Associated Pulmonary Arterial Hypertension. International Journal of Molecular Sciences. 19. PMID 30158434 DOI: 10.3390/Ijms19092561  0.341
2018 Halliday SJ, Xu M, Thayer TE, Mosley JD, Sheng Q, Ye F, Farber-Eger E, Pugh M, Robbins I, Assad TR, West JD, Brittain E, Hemnes A. EXPRESS: Clinical and Genetic Associations with Prostacyclin Response in Pulmonary Arterial Hypertension. Pulmonary Circulation. 2045894018800544. PMID 30142026 DOI: 10.1177/2045894018800544  0.313
2018 Bryant AJ, Mehrad B, Brusko TM, West JD, Moldawer LL. Myeloid-Derived Suppressor Cells and Pulmonary Hypertension. International Journal of Molecular Sciences. 19. PMID 30081463 DOI: 10.3390/Ijms19082277  0.367
2018 Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE, Johnson JA, Kaplowitz M, Newman JH, Piana R, ... ... West J, et al. A potential therapeutic role for Angiotensin Converting Enzyme 2 in human pulmonary arterial hypertension. The European Respiratory Journal. PMID 29903860 DOI: 10.1183/13993003.02638-2017  0.449
2018 Rathinasabapathy A, Bryant AJ, Suzuki T, Moore C, Shay S, Gladson S, West JD, Carrier EJ. rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling. Frontiers in Physiology. 9: 271. PMID 29731719 DOI: 10.3389/Fphys.2018.00271  0.371
2018 Das M, Zawada WM, West JD, Stenmark KR. EXPRESS: JNK2 Regulates Vascular Remodeling in Pulmonary Hypertension. Pulmonary Circulation. 2045894018778156. PMID 29718758 DOI: 10.1177/2045894018778156  0.38
2018 Rathinasabapathy A, Horowitz A, Horton K, Kumar A, Gladson S, Unger T, Martinez D, Bedse G, West J, Raizada MK, Steckelings UM, Sumners C, Katovich MJ, Shenoy V. The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury. Frontiers in Physiology. 9: 180. PMID 29636695 DOI: 10.3389/Fphys.2018.00180  0.411
2018 West JD, Carrier EJ. Precision Modeling of Pulmonary Hypertension Pathology with iPSC-derived Cells. American Journal of Respiratory and Critical Care Medicine. PMID 29596760 DOI: 10.1164/Rccm.201803-0480Ed  0.313
2018 Colbert R, Huang S, Assad T, Halliday S, D'Amico R, West J, Brittain E. Pulmonary Arterial Hypertension Clinical Profiles And Survival Using Latent Class Analysis Journal of the American College of Cardiology. 71. DOI: 10.1016/S0735-1097(18)32488-4  0.416
2017 Suzuki T, Tada Y, Gladson S, Nishimura R, Shimomura I, Karasawa S, Tatsumi K, West J. Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition. Respiratory Research. 18: 177. PMID 29037205 DOI: 10.1186/S12931-017-0660-4  0.378
2017 Chen X, Austin ED, Talati M, Fessel JP, Farber-Eger EH, Brittain EL, Hemnes AR, Loyd JE, West J. Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects. The European Respiratory Journal. 50. PMID 28775043 DOI: 10.1183/13993003.02337-2016  0.424
2017 Sakurai-Iesato Y, Kawata N, Tada Y, Iesato K, Matsuura Y, Yahaba M, Suzuki T, Ikari J, Yanagawa N, Kasahara Y, West J, Tatsumi K. The Relationship of Bone Mineral Density in Men with Chronic Obstructive Pulmonary Disease Classified According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Combined Chronic Obstructive Pulmonary Disease (COPD) Assessment System. Internal Medicine (Tokyo, Japan). 56: 1781-1790. PMID 28717072 DOI: 10.2169/Internalmedicine.56.6910  0.364
2017 Trammell AW, Talati M, Blackwell TR, Fortune NL, Niswender KD, Fessel JP, Newman JH, West JD, Hemnes AR. EXPRESS: Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension. Pulmonary Circulation. 689908. PMID 28704134 DOI: 10.1086/689908  0.334
2017 Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, ... ... West J, et al. Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension. Pulmonary Circulation. 7: 186-199. PMID 28680578 DOI: 10.1086/690236  0.355
2016 Frump AL, Datta A, Ghose S, West J, de Caestecker MP. Genotype-phenotype effects of Bmpr2 mutations on disease severity in mouse models of pulmonary hypertension. Pulmonary Circulation. 6: 597-607. PMID 28090303 DOI: 10.1086/688930  0.405
2016 Awad KS, West JD, de Jesus Perez V, MacLean M. Novel signaling pathways in pulmonary arterial hypertension (2015 Grover Conference Series). Pulmonary Circulation. 6: 285-94. PMID 27683605 DOI: 10.1086/688034  0.309
2016 Yan L, West J, Hamid R. Reply: Expanded Role for Bone Marrow-derived Hematopoietic Stem and Progenitor Cells in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. 194: 384-5. PMID 27479065 DOI: 10.1164/Rccm.201603-0611Le  0.381
2016 Austin ED, West J, Loyd JE, Hemnes AR. Molecular Medicine of Pulmonary Arterial Hypertension: From Population Genetics to Precision Medicine and Gene Editing. American Journal of Respiratory and Critical Care Medicine. PMID 27398627 DOI: 10.1164/Rccm.201605-0905Pp  0.404
2016 West JD, Voss BM, Pavliv L, de Caestecker M, Hemnes AR, Carrier EJ. Antagonism of the thromboxane-prostanoid receptor is cardioprotective against right ventricular pressure overload. Pulmonary Circulation. 6: 211-23. PMID 27252848 DOI: 10.1086/686140  0.309
2016 Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR. Mechanisms of Lipid Accumulation in the Bone Morphogenic Protein Receptor 2 Mutant Right Ventricle. American Journal of Respiratory and Critical Care Medicine. PMID 27077479 DOI: 10.1164/Rccm.201507-1444Oc  0.388
2016 Kapitsinou PP, Rajendran G, Astleford L, Michael M, Schonfeld MP, Fields T, Shay S, French JL, West J, Haase VH. The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice. Molecular and Cellular Biology. 36: 1584-94. PMID 26976644 DOI: 10.1128/Mcb.01055-15  0.439
2016 Hemnes AR, Zhao M, West J, Newman JH, Rich S, Archer SL, Robbins IM, Blackwell TS, Cogan J, Loyd JE, Zhao Z, Gaskill C, Jetter C, Kropski JA, Majka SM, et al. Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 26926454 DOI: 10.1164/Rccm.201508-1678Oc  0.417
2016 West JD, Carrier EJ, Bloodworth NC, Schroer AK, Chen P, Ryzhova LM, Gladson S, Shay S, Hutcheson JD, Merryman WD. Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. Plos One. 11: e0148657. PMID 26863209 DOI: 10.1371/Journal.Pone.0148657  0.327
2016 Kapitsinou P, Rajendran G, Astleford L, Schonfeld M, Michael M, Shay S, French J, West J, Haase V, Fields T. ID: 113: THE ENDOTHELIAL PHD2/HIF-2 AXIS REGULATES PULMONARY ARTERY PRESSURE IN MICE Journal of Investigative Medicine. 64: 961.2-962. DOI: 10.1136/Jim-2016-000120.103  0.416
2015 Bryant AJ, Robinson LJ, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, McClellan LJ, Polosukhin VV, Tanjore H, McConaha ME, Gleaves LA, Talati MA, Hemnes AR, Fessel JP, ... ... West JD, et al. Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis. Pulmonary Circulation. 5: 681-90. PMID 26697175 DOI: 10.1086/683811  0.36
2015 Yan L, Chen X, Talati M, Nunley BW, Gladson S, Blackwell T, Cogan J, Austin E, Wheeler F, Loyd J, West J, Hamid R. Bone Marrow-derived Cells Contribute to Pathogenesis of Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 26651104 DOI: 10.1164/Rccm.201502-0407Oc  0.448
2015 Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, ... ... West JD, et al. ENDOTHELIAL HIF SIGNALING REGULATES PULMONARY FIBROSIS-ASSOCIATED PULMONARY HYPERTENSION. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00258.2015. PMID 26637636 DOI: 10.1152/Ajplung.00258.2015  0.336
2015 Huang J, Wolk JH, Gewitz MH, Loyd JE, West J, Austin ED, Mathew R. Enhanced caveolin-1 expression in smooth muscle cells: Possible prelude to neointima formation. World Journal of Cardiology. 7: 671-84. PMID 26516422 DOI: 10.4330/Wjc.V7.I10.671  0.338
2015 Chen X, Talati M, Fessel JP, Hemnes AR, Gladson S, French J, Shay S, Trammell A, Phillips JA, Hamid R, Cogan JD, Dawson EP, Womble KE, Hedges LK, Martinez EG, ... ... West J, et al. The Estrogen Metabolite 16αOHE Exacerbates BMPR2-Associated PAH Through miR-29-Mediated Modulation of Cellular Metabolism. Circulation. PMID 26487756 DOI: 10.1161/Circulationaha.115.016133  0.377
2015 Suzuki T, Tada Y, Kawata N, Ikari J, Kasahara Y, Sakurai Y, Iesato K, Nishimura R, West J, Tatsumi K. Influence of pulmonary emphysema on COPD assessment test-oriented categorization in GOLD document. International Journal of Chronic Obstructive Pulmonary Disease. 10: 1199-1205. PMID 26150711 DOI: 10.2147/Copd.S82910  0.36
2015 Newman JH, Holt TN, Cogan JD, Womack B, Phillips JA, Li C, Kendall Z, Stenmark KR, Thomas MG, Brown RD, Riddle SR, West JD, Hamid R. Increased prevalence of EPAS1 variant in cattle with high-altitude pulmonary hypertension. Nature Communications. 6: 6863. PMID 25873470 DOI: 10.1038/ncomms7863  0.338
2015 Bloodworth NC, West JD, Merryman WD. Microvessel mechanobiology in pulmonary arterial hypertension: cause and effect. Hypertension. 65: 483-9. PMID 25534705 DOI: 10.1161/HYPERTENSIONAHA.114.04652  0.336
2015 Hemnes AR, Trammell AW, Archer SL, Rich S, Yu C, Nian H, Penner N, Funke M, Wheeler L, Robbins IM, Austin ED, Newman JH, West J. Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension. Circulation. 131: 401-9; discussion 40. PMID 25361553 DOI: 10.1161/Circulationaha.114.013317  0.413
2014 West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, et al. Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension. American Journal of Physiology. Cell Physiology. 307: C415-30. PMID 24871858 DOI: 10.1152/Ajpcell.00057.2014  0.317
2014 West J, Austin E, Fessel JP, Loyd J, Hamid R. Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension. Drug Discovery Today. 19: 1241-5. PMID 24794464 DOI: 10.1016/J.Drudis.2014.04.015  0.474
2014 Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K. BMP pathway regulation of and by macrophages Plos One. 9. PMID 24713633 DOI: 10.1371/Journal.Pone.0094119  0.411
2014 Hemnes AR, Brittain EL, Trammell AW, Fessel JP, Austin ED, Penner N, Maynard KB, Gleaves L, Talati M, Absi T, Disalvo T, West J. Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine. 189: 325-34. PMID 24274756 DOI: 10.1164/Rccm.201306-1086Oc  0.429
2014 Talati M, Mutlak H, Lane K, Han W, Hemnes A, Mutlak O, Blackwell T, Zaynagetdinov R, Blackwell T, West J. NF-κB Activation Exacerbates, but Is not Required for Murine Bmpr2-Related Pulmonary Hypertension Diseases. 2: 148-167. DOI: 10.3390/Diseases2020148  0.369
2013 Fessel JP, Chen X, Frump A, Gladson S, Blackwell T, Kang C, Johnson J, Loyd JE, Hemnes A, Austin E, West J. Interaction between bone morphogenetic protein receptor type 2 and estrogenic compounds in pulmonary arterial hypertension. Pulmonary Circulation. 3: 564-77. PMID 24618541 DOI: 10.1086/674312  0.427
2013 Brittain E, Penner NL, West J, Hemnes A. Echocardiographic assessment of the right heart in mice. Journal of Visualized Experiments. PMID 24326586 DOI: 10.3791/50912  0.438
2013 Austin ED, Lahm T, West J, Tofovic SP, Johansen AK, Maclean MR, Alzoubi A, Oka M. Gender, sex hormones and pulmonary hypertension. Pulmonary Circulation. 3: 294-314. PMID 24015330 DOI: 10.4103/2045-8932.114756  0.405
2013 Fessel JP, Flynn CR, Robinson LJ, Penner NL, Gladson S, Kang CJ, Wasserman DH, Hemnes AR, West JD. Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. American Journal of Respiratory Cell and Molecular Biology. 49: 778-87. PMID 23742019 DOI: 10.1165/Rcmb.2012-0463Oc  0.304
2013 Park SH, Chen WC, Hoffman C, Marsh LM, West J, Grunig G. Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene. Plos One. 8: e55180. PMID 23383100 DOI: 10.1371/Journal.Pone.0055180  0.43
2013 Chen WC, Park SH, Hoffman C, Philip C, Robinson L, West J, Grunig G. Right ventricular systolic pressure measurements in combination with harvest of lung and immune tissue samples in mice. Journal of Visualized Experiments : Jove. e50023. PMID 23354416 DOI: 10.3791/50023  0.401
2013 West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR. A potential role for insulin resistance in experimental pulmonary hypertension. The European Respiratory Journal. 41: 861-71. PMID 22936709 DOI: 10.1183/09031936.00030312  0.394
2012 Das M, Fessel J, Tang H, West J. A Process-Based Review of Mouse Models of Pulmonary Hypertension Pulmonary Circulation. 2: 415-433. PMID 23372926 DOI: 10.4103/2045-8932.105030  0.394
2012 Hemnes AR, Maynard KB, Champion HC, Gleaves L, Penner N, West J, Newman JH. Testosterone negatively regulates right ventricular load stress responses in mice. Pulmonary Circulation. 2: 352-8. PMID 23130103 DOI: 10.4103/2045-8932.101647  0.383
2012 Cogan J, Austin E, Hedges L, Womack B, West J, Loyd J, Hamid R. Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance. Circulation. 126: 1907-16. PMID 22923426 DOI: 10.1161/Circulationaha.112.106245  0.461
2012 Fessel JP, Hamid R, Wittmann BM, Robinson LJ, Blackwell T, Tada Y, Tanabe N, Tatsumi K, Hemnes AR, West JD. Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming. Pulmonary Circulation. 2: 201-13. PMID 22837861 DOI: 10.4103/2045-8932.97606  0.342
2012 Shigeta A, Tada Y, Wang JY, Ishizaki S, Tsuyusaki J, Yamauchi K, Kasahara Y, Iesato K, Tanabe N, Takiguchi Y, Sakamoto A, Tokuhisa T, Shibuya K, Hiroshima K, West J, et al. CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L141-51. PMID 22610351 DOI: 10.1152/Ajplung.00337.2011  0.304
2012 Austin ED, Ma L, LeDuc C, Berman Rosenzweig E, Borczuk A, Phillips JA, Palomero T, Sumazin P, Kim HR, Talati MH, West J, Loyd JE, Chung WK. Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension. Circulation. Cardiovascular Genetics. 5: 336-43. PMID 22474227 DOI: 10.1161/Circgenetics.111.961888  0.438
2012 Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2546-57. PMID 22415303 DOI: 10.1096/Fj.11-200907  0.317
2012 Austin ED, Hamid R, Hemnes AR, Loyd JE, Blackwell T, Yu C, Phillips Iii JA, Gaddipati R, Gladson S, Gu E, West J, Lane KB. BMPR2 expression is suppressed by signaling through the estrogen receptor. Biology of Sex Differences. 3: 6. PMID 22348410 DOI: 10.1186/2042-6410-3-6  0.384
2012 Flynn C, Zheng S, Yan L, Hedges L, Womack B, Fessel J, Cogan J, Austin E, Loyd J, West J, Zhao Z, Hamid R. Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance. American Journal of Respiratory Cell and Molecular Biology. 47: 20-7. PMID 22312021 DOI: 10.1165/Rcmb.2011-0251Oc  0.418
2012 Johnson JA, Hemnes AR, Perrien DS, Schuster M, Robinson LJ, Gladson S, Loibner H, Bai S, Blackwell TR, Tada Y, Harral JW, Talati M, Lane KB, Fagan KA, West J. Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L474-84. PMID 22180660 DOI: 10.1152/Ajplung.00202.2011  0.466
2012 Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proceedings of the National Academy of Sciences of the United States of America. 109: 2814-9. PMID 21576484 DOI: 10.1073/Pnas.1101139108  0.306
2011 West J, Hemnes A. Experimental and Transgenic Models of Pulmonary Hypertension Comprehensive Physiology. 1: 769-782. PMID 23737202 DOI: 10.1002/Cphy.C100003  0.433
2011 Austin ED, Menon S, Hemnes AR, Robinson LR, Talati M, Fox KL, Cogan JD, Hamid R, Hedges LK, Robbins I, Lane K, Newman JH, Loyd JE, West J. Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression. Pulmonary Circulation. 1: 389-98. PMID 22140629 DOI: 10.4103/2045-8932.87308  0.39
2011 Lane KL, Talati M, Austin E, Hemnes AR, Johnson JA, Fessel JP, Blackwell T, Mernaugh RL, Robinson L, Fike C, Roberts LJ, West J. Oxidative injury is a common consequence of BMPR2 mutations. Pulmonary Circulation. 1: 72-83. PMID 21904662 DOI: 10.4103/2045-8932.78107  0.364
2011 Yasuda T, Tada Y, Tanabe N, Tatsumi K, West J. Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L667-74. PMID 21856816 DOI: 10.1152/Ajplung.00423.2010  0.464
2011 West J. Are Obliterative Pulmonary Vascular Lesions Reversible American Journal of Respiratory and Critical Care Medicine. 184: 397-398. PMID 21844514 DOI: 10.1164/Rccm.201106-1095Ed  0.337
2011 Majka S, Hagen M, Blackwell T, Harral J, Johnson JA, Gendron R, Paradis H, Crona D, Loyd JE, Nozik-Grayck E, Stenmark KR, West J. Physiologic and molecular consequences of endothelial Bmpr2 mutation. Respiratory Research. 12: 84. PMID 21696628 DOI: 10.1186/1465-9921-12-84  0.426
2011 Johnson JA, West J, Maynard KB, Hemnes AR. ACE2 improves right ventricular function in a pressure overload model. Plos One. 6: e20828. PMID 21695173 DOI: 10.1371/Journal.Pone.0020828  0.414
2011 Nagayoshi M, Tada Y, West J, Ochiai E, Watanabe A, Toyotome T, Tanabe N, Takiguchi Y, Shigeta A, Yasuda T, Shibuya K, Kamei K, Tatsumi K. Inhalation of Stachybotrys chartarum evokes pulmonary arterial remodeling in mice, attenuated by Rho-kinase inhibitor. Mycopathologia. 172: 5-15. PMID 21505873 DOI: 10.1007/S11046-011-9400-3  0.435
2011 Jun D, Garat C, West J, Thorn N, Chow K, Cleaver T, Sullivan T, Torchia EC, Childs C, Shade T, Tadjali M, Lara A, Nozik-Grayck E, Malkoski S, Sorrentino B, et al. The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells (Dayton, Ohio). 29: 725-35. PMID 21312316 DOI: 10.1002/Stem.604  0.373
2011 Menon S, Fessel J, West J. Microarray studies in pulmonary arterial hypertension. International Journal of Clinical Practice. Supplement. 19-28. PMID 21176012 DOI: 10.1111/J.1742-1241.2010.02604.X  0.436
2010 Johnson J, Loyd J, West J. Effective treatments for PAH will require detailed knowledge of molecular aetiology. International Journal of Clinical Practice. 64: 3-4. PMID 20939840 DOI: 10.1111/J.1742-1241.2010.02526.X  0.383
2010 Talati M, West J, Blackwell TR, Loyd JE, Meyrick B. BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension American Journal of Physiology-Lung Cellular and Molecular Physiology. 299. PMID 20562228 DOI: 10.1152/Ajplung.00295.2009  0.422
2010 West J. Cross Talk Between Smad, MAPK, and Actin in the Etiology of Pulmonary Arterial Hypertension Advances in Experimental Medicine and Biology. 661: 265-278. PMID 20204736 DOI: 10.1007/978-1-60761-500-2_17  0.441
2009 Johnson JA, Vnencak-Jones CL, Cogan JD, Loyd JE, West J. Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension. Bmc Medical Genetics. 10: 58. PMID 19531247 DOI: 10.1186/1471-2350-10-58  0.427
2009 Takeda K, Okamoto M, de Langhe S, Dill E, Armstrong M, Reisdorf N, Irwin D, Koster M, Wilder J, Stenmark KR, West J, Klemm D, Gelfand EW, Nozik-Grayck E, Majka SM. Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease. Anatomical Record (Hoboken, N.J. : 2007). 292: 1045-61. PMID 19484746 DOI: 10.1002/Ar.20921  0.378
2009 Crona D, Harral J, Adnot S, Eddahibi S, West J. Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene Bmc Pulmonary Medicine. 9: 19-19. PMID 19426553 DOI: 10.1186/1471-2466-9-19  0.416
2008 West J, Cogan J, Geraci M, Robinson L, Newman J, Phillips JA, Lane K, Meyrick B, Loyd J. Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance. Bmc Medical Genomics. 1: 45-45. PMID 18823550 DOI: 10.1186/1755-8794-1-45  0.435
2008 West J, Harral J, Lane K, Deng Y, Ickes B, Crona D, Albu S, Stewart D, Fagan K. Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions American Journal of Physiology-Lung Cellular and Molecular Physiology. 295. PMID 18723761 DOI: 10.1152/Ajplung.90255.2008  0.434
2008 Saavedra MT, Hughes GJ, Sanders LA, Carr M, Rodman DM, Coldren CD, Geraci MW, Sagel SD, Accurso FJ, West J, Nick JA. Circulating RNA transcripts identify therapeutic response in cystic fibrosis lung disease. American Journal of Respiratory and Critical Care Medicine. 178: 929-38. PMID 18723435 DOI: 10.1164/Rccm.200803-387Oc  0.352
2008 Tada Y, Laudi S, Harral J, Carr M, Ivester C, Tanabe N, Takiguchi Y, Tatsumi K, Kuriyama T, Nichols WC, West J. Murine Pulmonary Response To Chronic Hypoxia Is Strain Specific Experimental Lung Research. 34: 313-323. PMID 18600498 DOI: 10.1080/01902140802093204  0.321
2008 Saavedra MT, Patterson AD, West J, Randell SH, Riches DW, Malcolm KC, Cool CD, Nick JA, Dinarello CA. Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways. American Journal of Respiratory Cell and Molecular Biology. 38: 679-88. PMID 18218994 DOI: 10.1165/Rcmb.2007-0282Oc  0.343
2008 Trott A, West JD, Klai? L, Westerheide SD, Silverman RB, Morimoto RI, Morano KA. Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. Molecular Biology of the Cell. 19: 1104-12. PMID 18199679 DOI: 10.1091/Mbc.E07-10-1004  0.657
2007 Irwin D, Helm K, Campbell N, Imamura M, Fagan K, Harral J, Carr M, Young KA, Klemm D, Gebb S, Dempsey EC, West J, Majka S. Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L941-51. PMID 17693487 DOI: 10.1152/Ajplung.00054.2007  0.312
2007 Laudi S, Trump S, Schmitz V, West J, McMurtry IF, Mutlak H, Christians U, Weimann J, Kaisers U, Steudel W. Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L630-8. PMID 17575010 DOI: 10.1152/Ajplung.00110.2006  0.423
2007 Tada Y, Majka S, Carr M, Harral J, Crona D, Kuriyama T, West J. Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH. American Journal of Physiology-Lung Cellular and Molecular Physiology. 292. PMID 17369292 DOI: 10.1152/Ajplung.00305.2006  0.443
2007 Hagen M, Fagan K, Steudel W, Carr M, Lane K, Rodman DM, West J. Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle American Journal of Physiology-Lung Cellular and Molecular Physiology. 292. PMID 17322283 DOI: 10.1152/Ajplung.00197.2006  0.427
2006 Young KA, Ivester C, West J, Carr M, Rodman DM. BMP signaling controls PASMC KV channel expression in vitro and in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L841-8. PMID 16339782 DOI: 10.1152/Ajplung.00158.2005  0.398
2005 Golembeski SM, West J, Tada Y, Fagan KA. Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice. Chest. 128: 572S-573S. PMID 16373831 DOI: 10.1378/Chest.128.6_Suppl.572S-A  0.444
2005 West J, Tada Y, Fagan KA, Steudel W, Fouty BW, Harral JW, Miller M, Ozimek J, Tuder RM, Rodman DM. Suppression of type II bone morphogenic protein receptor in vascular smooth muscle induces pulmonary arterial hypertension in transgenic mice. Chest. 128: 553S. PMID 16373822 DOI: 10.1378/Chest.128.6_Suppl.553S  0.412
2005 Rodman DM, Reese K, Harral J, Fouty B, Wu S, West J, Hoedt-Miller M, Tada Y, Li KX, Cool C, Fagan K, Cribbs L. Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes. Circulation Research. 96: 864-72. PMID 15774856 DOI: 10.1161/01.Res.0000163066.07472.Ff  0.306
2004 West J, Buchholz M, Fiero A, Tada Y, Fagan K, Rodman D. Adenoviral gene transfer to the neonatal rat pulmonary circulation. Journal of Gene Medicine. 6: 734-739. PMID 15241780 DOI: 10.1002/Jgm.565  0.368
2004 West J, Fagan K, Steudel W, Fouty B, Lane K, Harral J, Hoedt-Miller M, Tada Y, Ozimek J, Tuder R, Rodman DM. Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle. Circulation Research. 94: 1109-14. PMID 15031260 DOI: 10.1161/01.Res.0000126047.82846.20  0.462
2004 Tada Y, West J, Fagan K, Rodman DM. 222 Gene Expression Patterns In The Lungs Of Dominant Negative Bone Morphogenic Protein Receptor 2 Transgenic Mice. Journal of Investigative Medicine. 52. DOI: 10.1136/Jim-52-Suppl1-222  0.331
2001 West J, Rodman DM. Gene Therapy for Pulmonary Diseases Chest. 119: 613-617. PMID 11171744 DOI: 10.1378/Chest.119.2.613  0.333
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