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Hongbing Shu - Publications

Affiliations: 
1990-1992 University of Michigan, Ann Arbor, Ann Arbor, MI 
 1992-1995 Emory University, Atlanta, GA 
 1998- National Jewish Health 
 1999- Peking University, Beijing, Beijing Shi, China 
 2004- Wuhan University, Wuhan Shi, Hubei Sheng, China 
 2011- Chinese Academy of Sciences, Beijing, China 
Area:
immunology, TNF
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Year Citation  Score
2023 Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, Xie J, Zhou Y, Tian M, Zhang C, Sun X, Wang S, Cheng X, Zhang Y, Wei W, ... ... Shu HB, et al. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2. Nature Cell Biology. PMID 37443289 DOI: 10.1038/s41556-023-01185-x  0.3
2023 Guo Y, Zhang XN, Su S, Ruan ZL, Hu MM, Shu HB. β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response. Cellular & Molecular Immunology. PMID 36600052 DOI: 10.1038/s41423-022-00967-x  0.584
2022 Yang YL, Cao LB, He WR, Zhong L, Guo Y, Yang Q, Shu HB, Hu MM. Endocytosis triggers V-ATPase-SYK-mediated priming of cGAS activation and innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207280119. PMID 36252040 DOI: 10.1073/pnas.2207280119  0.441
2022 Zhong B, Shu HB. MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention. Current Opinion in Immunology. 78: 102248. PMID 36193584 DOI: 10.1016/j.coi.2022.102248  0.341
2022 Su S, Hua D, Li JP, Zhang XN, Bai L, Cao LB, Guo Y, Zhang M, Dong JZ, Liang XW, Lan K, Hu MM, Shu HB. Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone. Signal Transduction and Targeted Therapy. 7: 137. PMID 35468896 DOI: 10.1038/s41392-022-00981-5  0.525
2021 Li C, Feng L, Luo WW, Lei CQ, Li M, Shu HB. The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response. Cell Discovery. 7: 46. PMID 34155193 DOI: 10.1038/s41421-021-00277-y  0.541
2021 Guo W, Wei J, Zhong X, Zang R, Lian H, Hu MM, Li S, Shu HB, Yang Q. Correction to: SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. Cellular & Molecular Immunology. PMID 33958747 DOI: 10.1038/s41423-021-00682-z  0.438
2021 He WR, Cao LB, Yang YL, Hua D, Hu MM, Shu HB. VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release. Cellular & Molecular Immunology. PMID 33785841 DOI: 10.1038/s41423-021-00673-0  0.41
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Shu HB, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.469
2020 Sun X, Liu T, Zhao J, Xia H, Xie J, Guo Y, Zhong L, Li M, Yang Q, Peng C, Rouvet I, Belot A, Shu HB, Feng P, Zhang J. DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity. Nature Communications. 11: 6182. PMID 33273464 DOI: 10.1038/s41467-020-19941-0  0.311
2020 Song ZM, Lin H, Yi XM, Guo W, Hu MM, Shu HB. KAT5 acetylates cGAS to promote innate immune response to DNA virus. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817552 DOI: 10.1073/pnas.1922330117  0.39
2020 Li M, Shu HB. Dephosphorylation of cGAS by PPP6C impairs its substrate binding activity and innate antiviral response. Protein & Cell. PMID 32474700 DOI: 10.1007/s13238-020-00729-3  0.424
2020 Liao CY, Lei CQ, Shu HB. PCBP1 modulates the innate immune response by facilitating the binding of cGAS to DNA. Cellular & Molecular Immunology. PMID 32415261 DOI: 10.1038/S41423-020-0462-3  0.33
2020 Zhong X, Feng L, Zang R, Lei CQ, Yang Q, Shu HB. ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response. Plos Pathogens. 16: e1008457. PMID 32251420 DOI: 10.1371/Journal.Ppat.1008457  0.492
2020 Gao P, Hu MM, Shu HB. CSK promotes innate immune response to DNA virus by phosphorylating MITA. Biochemical and Biophysical Research Communications. PMID 32201077 DOI: 10.1016/j.bbrc.2020.03.069  0.461
2020 Zang R, Lian H, Zhong X, Yang Q, Shu HB. ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3. Journal of Molecular Cell Biology. PMID 32133501 DOI: 10.1093/jmcb/mjaa004  0.378
2020 Yang Q, Shu HB. Deciphering the pathways to antiviral innate immunity and inflammation. Advances in Immunology. 145: 1-36. PMID 32081195 DOI: 10.1016/bs.ai.2019.11.001  0.491
2020 Chuan G, Chen L, Tang SB, Long QY, He JL, Zhang NA, Shu HB, Chen ZX, Wu M, Li LY. The epigenetic landscapes of histone modifications on HSV-1 genome in human THP-1 cells. Antiviral Research. 104730. PMID 32014498 DOI: 10.1016/j.antiviral.2020.104730  0.315
2019 Xia T, Yi XM, Wu X, Shang J, Shu HB. PTPN1/2-mediated dephosphorylation of MITA/STING promotes its 20S proteasomal degradation and attenuates innate antiviral response. Proceedings of the National Academy of Sciences of the United States of America. PMID 31527250 DOI: 10.1073/pnas.1906431116  0.527
2019 Guo W, Wei J, Zhong X, Zang R, Lian H, Hu MM, Li S, Shu HB, Yang Q. SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA. Cellular & Molecular Immunology. PMID 31511639 DOI: 10.1038/s41423-019-0285-2  0.559
2019 Wu X, Lei C, Xia T, Zhong X, Yang Q, Shu HB. Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination. Nature Communications. 10: 4115. PMID 31511519 DOI: 10.1038/S41467-019-12145-1  0.376
2019 Lin H, Li S, Shu HB. The Membrane-Associated MARCH E3 Ligase Family: Emerging Roles in Immune Regulation. Frontiers in Immunology. 10: 1751. PMID 31404274 DOI: 10.3389/fimmu.2019.01751  0.353
2019 Zhong X, Feng L, Xu WH, Wu X, Ding YD, Zhou Y, Lei CQ, Shu HB. The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding. Cellular & Molecular Immunology. PMID 31388100 DOI: 10.1038/S41423-019-0265-6  0.307
2019 Li D, Fu S, Wu Z, Yang W, Ru Y, Shu H, Liu X, Zheng H. DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. Journal of Cell Science. 133. PMID 31340999 DOI: 10.1242/jcs.230409  0.47
2019 Hu MM, He WR, Gao P, Yang Q, He K, Cao LB, Li S, Feng YQ, Shu HB. Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity. Cell Research. PMID 30651583 DOI: 10.1038/s41422-018-0136-1  0.523
2018 Sun MS, Zhang J, Jiang LQ, Pan YX, Tan JY, Yu F, Guo L, Yin L, Shen C, Shu HB, Liu Y. TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. Cell Reports. 25: 3086-3098.e3. PMID 30540941 DOI: 10.1016/j.celrep.2018.11.048  0.452
2018 Xie T, Chen T, Li C, Wang W, Cao L, Rao H, Yang Q, Shu HB, Xu LG. RACK1 attenuates RLR antiviral signaling by targeting VISA-TRAF complexes. Biochemical and Biophysical Research Communications. PMID 30527812 DOI: 10.1016/j.bbrc.2018.11.203  0.507
2018 Ling T, Li SN, Weng GX, Wang W, Li C, Cao L, Rao H, Shu HB, Xu LG. TARBP2 negatively regulates IFN-β production and innate antiviral response by targeting MAVS. Molecular Immunology. 104: 1-10. PMID 30390472 DOI: 10.1016/j.molimm.2018.10.017  0.523
2018 Wei J, Lian H, Guo W, Chen YD, Zhang XN, Zang R, Zhong L, Yang Q, Hu MM, Luo WW, Shu HB, Li S. SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA. Plos Pathogens. 14: e1007336. PMID 30321235 DOI: 10.1371/journal.ppat.1007336  0.423
2018 Lian H, Zang R, Wei J, Ye W, Hu MM, Chen YD, Zhang XN, Guo Y, Lei CQ, Yang Q, Luo WW, Li S, Shu HB. The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors. Immunity. PMID 30193849 DOI: 10.1016/J.Immuni.2018.08.014  0.507
2018 Lian H, Wei J, Zang R, Ye W, Yang Q, Zhang XN, Chen YD, Fu YZ, Hu MM, Lei CQ, Luo WW, Li S, Shu HB. ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response. Nature Communications. 9: 3349. PMID 30135424 DOI: 10.1038/S41467-018-05559-W  0.459
2018 Hu MM, Shu HB. Cytoplasmic Mechanisms of Recognition and Defense of Microbial Nucleic Acids. Annual Review of Cell and Developmental Biology. PMID 30095291 DOI: 10.1146/annurev-cellbio-100617-062903  0.303
2018 Wang J, Zeng Y, Xu S, Yang J, Wang W, Zhong B, Ge J, Yin L, Bu Z, Shu HB, Chen H, Lei CQ, Zhu Q. A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity. Journal of Virology. PMID 29563291 DOI: 10.1128/Jvi.00149-18  0.459
2018 Luo WW, Shu HB. Delicate regulation of the cGAS-MITA-mediated innate immune response. Cellular & Molecular Immunology. PMID 29456253 DOI: 10.1038/cmi.2016.51  0.345
2018 Liu Y, Zhou Q, Zhong L, Lin H, Hu MM, Zhou Y, Shu HB, Li S. ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association. Cellular & Molecular Immunology. PMID 29429998 DOI: 10.1038/cmi.2017.146  0.484
2017 Shang J, Xia T, Han QQ, Zhao X, Hu MM, Shu HB, Guo L. Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-induced Innate Immunity. Proteomics. PMID 29251827 DOI: 10.1002/pmic.201700403  0.373
2017 Wei J, Guo W, Lian H, Yang Q, Lin H, Li S, Shu HB. SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes. Proceedings of the National Academy of Sciences of the United States of America. 114: 13000-13005. PMID 29180417 DOI: 10.1073/pnas.1713462114  0.38
2017 Luo WW, Li S, Li C, Zheng ZQ, Cao P, Tong Z, Lian H, Wang SY, Shu HB, Wang YY. iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA. Plos Pathogens. 13: e1006693. PMID 29155878 DOI: 10.1371/journal.ppat.1006693  0.565
2017 Yan BR, Zhou L, Hu MM, Li M, Lin H, Yang Y, Wang YY, Shu HB. PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation. Plos Pathogens. 13: e1006648. PMID 28934360 DOI: 10.1371/journal.ppat.1006648  0.361
2017 Yang Q, Liu TT, Lin H, Zhang M, Wei J, Luo WW, Hu YH, Zhong B, Hu MM, Shu HB. TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses. Plos Pathogens. 13: e1006600. PMID 28898289 DOI: 10.1371/journal.ppat.1006600  0.413
2017 Qin Y, Li M, Zhou SL, Yin W, Bian Z, Shu HB. SPI-2/CrmA inhibits IFN-β induction by targeting TBK1/IKKε. Scientific Reports. 7: 10495. PMID 28874755 DOI: 10.1038/s41598-017-11016-3  0.491
2017 Luo WW, Shu HB. Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses. Febs Letters. PMID 28815577 DOI: 10.1002/1873-3468.12796  0.359
2017 Ye W, Hu MM, Lei CQ, Zhou Q, Lin H, Sun MS, Shu HB. TRIM8 Negatively Regulates TLR3/4-Mediated Innate Immune Response by Blocking TRIF-TBK1 Interaction. Journal of Immunology (Baltimore, Md. : 1950). PMID 28747347 DOI: 10.4049/Jimmunol.1601647  0.393
2017 Sun H, Zhang Q, Jing YY, Zhang M, Wang HY, Cai Z, Liuyu T, Zhang ZD, Xiong TC, Wu Y, Zhu QY, Yao J, Shu HB, Lin D, Zhong B. USP13 negatively regulates antiviral responses by deubiquitinating STING. Nature Communications. 8: 15534. PMID 28534493 DOI: 10.1038/ncomms15534  0.499
2017 Jiang LQ, Xia T, Hu YH, Sun MS, Yan S, Lei CQ, Shu HB, Guo JH, Liu Y. IFITM3 inhibits virus-triggered induction of type I interferon by mediating autophagosome-dependent degradation of IRF3. Cellular & Molecular Immunology. PMID 28435159 DOI: 10.1038/Cmi.2017.15  0.538
2017 Hu MM, Liao CY, Yang Q, Xie XQ, Shu HB. Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5. The Journal of Experimental Medicine. PMID 28250012 DOI: 10.1084/jem.20161015  0.505
2017 Hu MM, Shu HB. Multifaceted roles of TRIM38 in innate immune and inflammatory responses. Cellular & Molecular Immunology. PMID 28194022 DOI: 10.1038/cmi.2016.66  0.426
2017 Fu YZ, Su S, Gao YQ, Wang PP, Huang ZF, Hu MM, Luo WW, Li S, Luo MH, Wang YY, Shu HB. Human Cytomegalovirus Tegument Protein UL82 Inhibits STING-Mediated Signaling to Evade Antiviral Immunity. Cell Host & Microbe. PMID 28132838 DOI: 10.1016/j.chom.2017.01.001  0.47
2016 Wang J, Lei CQ, Ji Y, Zhou H, Ren Y, Peng Q, Zeng Y, Jia Y, Ge J, Zhong B, Li Y, Wei J, Shu HB, Zhu Q. Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA. Journal of Immunology (Baltimore, Md. : 1950). PMID 27821666 DOI: 10.4049/Jimmunol.1502317  0.505
2016 Zhang M, Zhang MX, Zhang Q, Zhu GF, Yuan L, Zhang DE, Zhu Q, Yao J, Shu HB, Zhong B. USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA. Cell Research. PMID 27801882 DOI: 10.1038/cr.2016.125  0.494
2016 Zhu Z, Wang G, Yang F, Cao W, Mao R, Du X, Zhang X, Li C, Li D, Zhang K, Shu H, Liu X, Zheng H. Foot-and-mouth disease virus viroporin 2B antagonizes RIG-I mediated antiviral effects by inhibition of its protein expression. Journal of Virology. PMID 27707918 DOI: 10.1128/JVI.01310-16  0.36
2016 Hu MM, Yang Q, Xie XQ, Liao CY, Lin H, Liu TT, Yin L, Shu HB. Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus. Immunity. PMID 27637147 DOI: 10.1016/j.immuni.2016.08.014  0.483
2016 Luo WW, Li S, Li C, Lian H, Yang Q, Zhong B, Shu HB. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nature Immunology. PMID 27428826 DOI: 10.1038/ni.3510  0.447
2016 Chen LT, Hu MM, Xu ZS, Liu Y, Shu HB. MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes. Journal of Immunology (Baltimore, Md. : 1950). PMID 27194789 DOI: 10.4049/jimmunol.1600039  0.534
2016 Liu TT, Yang Q, Li M, Zhong B, Ran Y, Liu LL, Yang Y, Wang YY, Shu HB. LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner. Journal of Immunology (Baltimore, Md. : 1950). PMID 27183626 DOI: 10.4049/jimmunol.1600212  0.533
2016 Ren Y, Zhao Y, Lin D, Xu X, Zhu Q, Yao J, Shu HB, Zhong B. The type I interferon-IRF7 axis mediates transcriptional expression of Usp25. The Journal of Biological Chemistry. PMID 27129230 DOI: 10.1074/jbc.M116.718080  0.439
2016 Li D, Wei J, Yang F, Liu HN, Zhu ZX, Cao WJ, Li S, Liu XT, Zheng HX, Shu HB. Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways. Cell Cycle (Georgetown, Tex.). 0. PMID 26901336 DOI: 10.1080/15384101.2016.1151584  0.423
2016 Li D, Lei C, Xu Z, Yang F, Liu H, Zhu Z, Li S, Liu X, Shu H, Zheng H. Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-β signaling pathway. Scientific Reports. 6: 21888. PMID 26883855 DOI: 10.1038/Srep21888  0.302
2016 Li D, Yang W, Yang F, Liu H, Zhu Z, Lian K, Lei C, Li S, Liu X, Zheng H, Shu H. The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-β signaling pathway. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26813975 DOI: 10.1096/Fj.15-281410  0.439
2015 Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S, Zhao X, Lei CQ, Guo L, Chen Y, Li CM, Jokitalo E, Yin Y, Shu HB, Guo D. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nature Immunology. PMID 26692175 DOI: 10.1038/Ni.3311  0.369
2015 An T, Li S, Pan W, Tien P, Zhong B, Shu HB, Wu S. DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation. Plos Pathogens. 11: e1005179. PMID 26407194 DOI: 10.1371/journal.ppat.1005179  0.563
2015 Hu MM, Xie XQ, Yang Q, Liao CY, Ye W, Lin H, Shu HB. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. Journal of Immunology (Baltimore, Md. : 1950). PMID 26392463 DOI: 10.4049/jimmunol.1500859  0.423
2015 Lin D, Zhang M, Zhang MX, Ren Y, Zhao Q, Jin J, Pan Z, Wu M, Shu HB, Dong C, Zhong B. Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6. Proceedings of the National Academy of Sciences of the United States of America. PMID 26305951 DOI: 10.1073/pnas.1509968112  0.523
2015 Wei J, Lian H, Zhong B, Shu HB. Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1. Journal of Immunology (Baltimore, Md. : 1950). 195: 2870-8. PMID 26232434 DOI: 10.4049/jimmunol.1501111  0.376
2015 Zhou MT, Qin Y, Li M, Chen C, Chen X, Shu HB, Guo L. Quantitative proteomics reveals the roles of peroxisome-associated proteins in anti-viral innate immune responses. Molecular & Cellular Proteomics : McP. PMID 26124285 DOI: 10.1074/mcp.M115.048413  0.377
2015 Lei CQ, Zhang Y, Li M, Jiang LQ, Zhong B, Kim YH, Shu HB. ECSIT bridges RIG-I-like receptors to VISA in signaling events of innate antiviral responses. Journal of Innate Immunity. 7: 153-64. PMID 25228397 DOI: 10.1159/000365971  0.535
2014 Luo WW, Lian H, Zhong B, Shu HB, Li S. Krüppel-like factor 4 negatively regulates cellular antiviral immune response. Cellular & Molecular Immunology. PMID 25531393 DOI: 10.1038/cmi.2014.125  0.378
2014 Zhou Q, Lin H, Wang S, Wang S, Ran Y, Liu Y, Ye W, Xiong X, Zhong B, Shu HB, Wang YY. The ER-associated protein ZDHHC1 is a positive regulator of DNA virus-triggered, MITA/STING-dependent innate immune signaling. Cell Host & Microbe. 16: 450-61. PMID 25299331 DOI: 10.1016/j.chom.2014.09.006  0.51
2014 Qin Y, Zhou MT, Hu MM, Hu YH, Zhang J, Guo L, Zhong B, Shu HB. RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms. Plos Pathogens. 10: e1004358. PMID 25254379 DOI: 10.1371/Journal.Ppat.1004358  0.568
2014 Ran Y, Shu HB, Wang YY. MITA/STING: a central and multifaceted mediator in innate immune response. Cytokine & Growth Factor Reviews. 25: 631-9. PMID 24929887 DOI: 10.1016/j.cytogfr.2014.05.003  0.382
2014 Yan J, Li Q, Mao AP, Hu MM, Shu HB. TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination. Journal of Molecular Cell Biology. 6: 154-63. PMID 24755855 DOI: 10.1093/jmcb/mju005  0.537
2014 Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM, Zhang Z, Schneider M, Jiang Y, Fitzgerald KA, Ouyang S, Liu ZJ, Damania B, Shu HB, Duncan JA, et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity. 40: 329-41. PMID 24560620 DOI: 10.1016/J.Immuni.2014.01.010  0.414
2014 Zhang J, Hu MM, Shu HB, Li S. Death-associated protein kinase 1 is an IRF3/7-interacting protein that is involved in the cellular antiviral immune response. Cellular & Molecular Immunology. 11: 245-52. PMID 24531619 DOI: 10.1038/Cmi.2013.65  0.567
2013 Liu Z, Wu SW, Lei CQ, Zhou Q, Li S, Shu HB, Wang YY. Heat shock cognate 71 (HSC71) regulates cellular antiviral response by impairing formation of VISA aggregates. Protein & Cell. 4: 373-82. PMID 23636689 DOI: 10.1007/S13238-013-3902-3  0.507
2013 Ding Q, Cao X, Lu J, Huang B, Liu YJ, Kato N, Shu HB, Zhong J. Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity. Journal of Hepatology. 59: 52-8. PMID 23542348 DOI: 10.1016/j.jhep.2013.03.019  0.334
2013 Lei CQ, Zhang Y, Xia T, Jiang LQ, Zhong B, Shu HB. FoxO1 negatively regulates cellular antiviral response by promoting degradation of IRF3. The Journal of Biological Chemistry. 288: 12596-604. PMID 23532851 DOI: 10.1074/Jbc.M112.444794  0.533
2013 Yang Y, Liao B, Wang S, Yan B, Jin Y, Shu HB, Wang YY. E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5115-20. PMID 23479606 DOI: 10.1073/pnas.1220271110  0.431
2013 Chen H, Li Y, Zhang J, Ran Y, Wei J, Yang Y, Shu HB. RAVER1 is a coactivator of MDA5-mediated cellular antiviral response. Journal of Molecular Cell Biology. 5: 111-9. PMID 23390309 DOI: 10.1093/Jmcb/Mjt006  0.528
2013 Zheng H, Li Q, Chen R, Zhang J, Ran Y, He X, Li S, Shu HB. The dual-specificity phosphatase DUSP14 negatively regulates tumor necrosis factor- and interleukin-1-induced nuclear factor-κB activation by dephosphorylating the protein kinase TAK1. The Journal of Biological Chemistry. 288: 819-25. PMID 23229544 DOI: 10.1074/Jbc.M112.412643  0.334
2012 Li Y, He X, Wang S, Shu HB, Liu Y. USP2a positively regulates TCR-induced NF-κB activation by bridging MALT1-TRAF6. Protein & Cell. 4: 62-70. PMID 23264041 DOI: 10.1007/s13238-012-2120-8  0.313
2012 Wang YY, Ran Y, Shu HB. Linear ubiquitination of NEMO brakes the antiviral response. Cell Host & Microbe. 12: 129-31. PMID 22901534 DOI: 10.1016/j.chom.2012.07.006  0.406
2012 Li Y, Chen R, Zhou Q, Xu Z, Li C, Wang S, Mao A, Zhang X, He W, Shu HB. LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 11770-5. PMID 22745163 DOI: 10.1073/pnas.1203405109  0.349
2012 Zhang J, Hu M, Wang Y, Shu H. TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination Journal of Biological Chemistry. 287: 28646-28655. PMID 22745133 DOI: 10.1074/Jbc.M112.362608  0.511
2012 He X, Li Y, Li C, Liu LJ, Zhang XD, Liu Y, Shu HB. USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6. Journal of Molecular Cell Biology. 5: 39-47. PMID 22611252 DOI: 10.1093/jmcb/mjs024  0.318
2012 Liu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB. Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosome. The Journal of Biological Chemistry. 287: 20081-7. PMID 22528498 DOI: 10.1074/jbc.M111.335463  0.345
2011 Li Q, Yan J, Mao AP, Li C, Ran Y, Shu HB, Wang YY. Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 108: 19341-6. PMID 22084099 DOI: 10.1073/pnas.1110946108  0.364
2011 Ran Y, Liu TT, Zhou Q, Li S, Mao AP, Li Y, Liu LJ, Cheng JK, Shu HB. SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. Journal of Molecular Cell Biology. 3: 283-92. PMID 22028379 DOI: 10.1093/jmcb/mjr020  0.498
2010 Zhong B, Wang YY, Shu HB. Regulation of virus-triggered type I interferon signaling by cellular and viral proteins. Frontiers in Biology. 5: 12-31. PMID 32215003 DOI: 10.1007/s11515-010-0013-x  0.421
2010 Lei CQ, Zhong B, Zhang Y, Zhang J, Wang S, Shu HB. Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1. Immunity. 33: 878-89. PMID 21145761 DOI: 10.1016/J.Immuni.2010.11.021  0.536
2010 Zhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB. The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. Journal of Immunology (Baltimore, Md. : 1950). 184: 6249-55. PMID 20483786 DOI: 10.4049/jimmunol.0903748  0.511
2010 Chen R, Zhang L, Zhong B, Tan B, Liu Y, Shu HB. The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling. Cell Research. 20: 802-11. PMID 20368735 DOI: 10.1038/cr.2010.41  0.444
2010 Han KJ, Yang Y, Xu LG, Shu HB. Analysis of a TIR-less splice variant of TRIF reveals an unexpected mechanism of TLR3-mediated signaling Journal of Biological Chemistry. 285: 12543-12550. PMID 20200155 DOI: 10.1074/jbc.M109.072231  0.346
2010 Mao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB. Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response. The Journal of Biological Chemistry. 285: 9470-6. PMID 20097753 DOI: 10.1074/jbc.M109.071043  0.529
2010 Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu HB. Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. The Journal of Biological Chemistry. 285: 4291-7. PMID 19996094 DOI: 10.1074/jbc.M109.074971  0.485
2009 Li Y, Li C, Xue P, Zhong B, Mao AP, Ran Y, Chen H, Wang YY, Yang F, Shu HB. ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response. Proceedings of the National Academy of Sciences of the United States of America. 106: 7945-50. PMID 19416887 DOI: 10.1073/pnas.0900818106  0.473
2009 Zhong B, Zhang L, Lei C, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB. The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity. 30: 397-407. PMID 19285439 DOI: 10.1016/J.Immuni.2009.01.008  0.52
2008 Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity. 29: 538-50. PMID 18818105 DOI: 10.1016/J.Immuni.2008.09.003  0.506
2008 Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, Chen DY, Zhai ZH, Shu HB. Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. Cell Research. 18: 1096-104. PMID 18711448 DOI: 10.1038/cr.2008.277  0.518
2007 Diao F, Li S, Tian Y, Zhang M, Xu LG, Zhang Y, Wang RP, Chen D, Zhai Z, Zhong B, Tien P, Shu HB. Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase. Proceedings of the National Academy of Sciences of the United States of America. 104: 11706-11. PMID 17600090 DOI: 10.1073/pnas.0700544104  0.49
2006 Zhong B, Tien P, Shu HB. Innate immune responses: crosstalk of signaling and regulation of gene transcription. Virology. 352: 14-21. PMID 16753195 DOI: 10.1016/j.virol.2006.04.029  0.377
2006 Zha J, Han KJ, Xu LG, He W, Zhou Q, Chen D, Zhai Z, Shu HB. The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members. Journal of Immunology (Baltimore, Md. : 1950). 176: 1072-80. PMID 16393995 DOI: 10.4049/Jimmunol.176.2.1072  0.422
2006 Su X, Li S, Meng M, Qian W, Xie W, Chen D, Zhai Z, Shu HB. TNF receptor-associated factor-1 (TRAF1) negatively regulates Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling. European Journal of Immunology. 36: 199-206. PMID 16323247 DOI: 10.1002/Eji.200535415  0.426
2005 Huang J, Liu T, Xu LG, Chen D, Zhai Z, Shu HB. SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. The Embo Journal. 24: 4018-28. PMID 16281057 DOI: 10.1038/sj.emboj.7600863  0.446
2005 Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Molecular Cell. 19: 727-40. PMID 16153868 DOI: 10.1016/j.molcel.2005.08.014  0.43
2005 Li L, Bin LH, Li F, Liu Y, Chen D, Zhai Z, Shu HB. TRIP6 is a RIP2-associated common signaling component of multiple NF-kappaB activation pathways. Journal of Cell Science. 118: 555-63. PMID 15657077 DOI: 10.1242/jcs.01641  0.317
2004 Wang YY, Li L, Han KJ, Zhai Z, Shu HB. A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter. Febs Letters. 576: 86-90. PMID 15474016 DOI: 10.1016/j.febslet.2004.08.071  0.394
2004 Han KJ, Su X, Xu LG, Bin LH, Zhang J, Shu HB. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. The Journal of Biological Chemistry. 279: 15652-61. PMID 14739303 DOI: 10.1074/jbc.M311629200  0.416
2002 Zhou J, Shu HB, Joshi HC. Regulation of tubulin synthesis and cell cycle progression in mammalian cells by gamma-tubulin-mediated microtubule nucleation. Journal of Cellular Biochemistry. 84: 472-83. PMID 11813253 DOI: 10.1002/Jcb.10033  0.458
Low-probability matches (unlikely to be authored by this person)
2013 Wang S, Li Y, Hu YH, Song R, Gao Y, Liu HY, Shu HB, Liu Y. STUB1 is essential for T-cell activation by ubiquitinating CARMA1. European Journal of Immunology. 43: 1034-41. PMID 23322406 DOI: 10.1002/eji.201242554  0.29
2015 Hu YH, Zhang Y, Jiang LQ, Wang S, Lei CQ, Sun MS, Shu HB, Liu Y. WDFY1 mediates TLR3/4 signaling by recruiting TRIF. Embo Reports. 16: 447-55. PMID 25736436 DOI: 10.15252/Embr.201439637  0.287
2004 Zhang J, Xu LG, Han KJ, Wei X, Shu HB. PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis. Febs Letters. 570: 97-101. PMID 15251447 DOI: 10.1016/j.febslet.2004.05.081  0.282
2012 Yang Z, Liang H, Zhou Q, Li Y, Chen H, Ye W, Chen D, Fleming J, Shu H, Liu Y. Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. Cell Research. 22: 1328-38. PMID 22825553 DOI: 10.1038/cr.2012.111  0.281
2003 Huang J, Teng L, Liu T, Li L, Chen D, Li F, Xu LG, Zhai Z, Shu HB. Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced transcription. Biochemical and Biophysical Research Communications. 309: 774-8. PMID 13679039 DOI: 10.1016/J.BBRC.2003.08.069  0.279
2023 Hu MM, Shu HB. Mitochondrial DNA-triggered innate immune response: mechanisms and diseases. Cellular & Molecular Immunology. PMID 37932533 DOI: 10.1038/s41423-023-01086-x  0.277
2016 Xu ZS, Zhang HX, Zhang YL, Liu TT, Ran Y, Chen LT, Wang YY, Shu HB. PASD1 promotes STAT3 activity and tumor growth by inhibiting TC45-mediated dephosphorylation of STAT3 in the nucleus. Journal of Molecular Cell Biology. PMID 26892021 DOI: 10.1093/jmcb/mjw005  0.276
2010 Wang YY, Liu LJ, Zhong B, Liu TT, Li Y, Yang Y, Ran Y, Li S, Tien P, Shu HB. WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation. Proceedings of the National Academy of Sciences of the United States of America. 107: 815-20. PMID 20080758 DOI: 10.1073/pnas.0908967107  0.275
2003 Wu M, Xu LG, Zhai Z, Shu HB. SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription. The Journal of Biological Chemistry. 278: 27072-9. PMID 12736262 DOI: 10.1074/jbc.M209814200  0.272
2003 Chen D, Xu LG, Chen L, Li L, Zhai Z, Shu HB. NIK is a component of the EGF/heregulin receptor signaling complexes. Oncogene. 22: 4348-55. PMID 12853971 DOI: 10.1038/sj.onc.1206532  0.271
2003 Chen D, Li Z, Yang Q, Zhang J, Zhai Z, Shu HB. Identification of a nuclear protein that promotes NF-kappaB activation. Biochemical and Biophysical Research Communications. 310: 720-4. PMID 14550261 DOI: 10.1016/j.bbrc.2003.09.074  0.271
2011 Zha J, Shu H. Molecular mechanism of signaling by tumor necrosis factor. Science in China. Series C, Life Sciences. 45: 113-9. PMID 18763070 DOI: 10.1360/02yc9013  0.269
2008 Han KJ, Jiang L, Shu HB. Regulation of IRF2 transcriptional activity by its sumoylation Biochemical and Biophysical Research Communications. 372: 772-778. PMID 18514056 DOI: 10.1016/j.bbrc.2008.05.103  0.264
2019 Lei CQ, Wu X, Zhong X, Jiang L, Zhong B, Shu HB. USP19 Inhibits TNF-α- and IL-1β-Triggered NF-κB Activation by Deubiquitinating TAK1. Journal of Immunology (Baltimore, Md. : 1950). PMID 31127032 DOI: 10.4049/Jimmunol.1900083  0.257
2020 Gong K, Zhang Z, Chen Y, Shu HB, Li W. Corrigendum to 'Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma' [Eur. J. Pharmacol. 738 (2014) 142-152]. European Journal of Pharmacology. 173462. PMID 32838984 DOI: 10.1016/j.ejphar.2020.173462  0.255
2007 Tian Y, Zhang Y, Zhong B, Wang YY, Diao FC, Wang RP, Zhang M, Chen DY, Zhai ZH, Shu HB. RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. The Journal of Biological Chemistry. 282: 16776-82. PMID 17449468 DOI: 10.1074/jbc.M701913200  0.252
2023 Cao LB, Ruan ZL, Yang YL, Zhang NC, Gao C, Cai C, Zhang J, Hu MM, Shu HB. Estrogen receptor α-mediated signaling inhibits type I interferon response to promote breast cancer. Journal of Molecular Cell Biology. PMID 37442610 DOI: 10.1093/jmcb/mjad047  0.252
2014 Hu MM, Yang Q, Zhang J, Liu SM, Zhang Y, Lin H, Huang ZF, Wang YY, Zhang XD, Zhong B, Shu HB. TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3. Proceedings of the National Academy of Sciences of the United States of America. 111: 1509-14. PMID 24434549 DOI: 10.1073/Pnas.1318227111  0.251
2004 Xu LG, Li LY, Shu HB. TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis. The Journal of Biological Chemistry. 279: 17278-82. PMID 15001576 DOI: 10.1074/jbc.C400063200  0.251
2018 Zhang HX, Xu ZS, Lin H, Li M, Xia T, Cui K, Wang SY, Li Y, Shu HB, Wang YY. TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis. Nature Communications. 9: 3441. PMID 30143645 DOI: 10.1038/s41467-018-05796-z  0.247
2021 Kang X, Chen X, He Y, Guo D, Guo L, Zhong J, Shu HB. Corrigendum to "DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication" [Virology 435 (2013) 385-394]. Virology. PMID 33573866 DOI: 10.1016/j.virol.2021.01.013  0.246
2004 Zha J, Zhou Q, Xu LG, Chen D, Li L, Zhai Z, Shu HB. RIP5 is a RIP-homologous inducer of cell death. Biochemical and Biophysical Research Communications. 319: 298-303. PMID 15178406 DOI: 10.1016/J.Bbrc.2004.04.194  0.246
2012 Chen R, Li M, Zhang Y, Zhou Q, Shu HB. The E3 ubiquitin ligase MARCH8 negatively regulates IL-1β-induced NF-κB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation. Proceedings of the National Academy of Sciences of the United States of America. 109: 14128-33. PMID 22904187 DOI: 10.1073/pnas.1205246109  0.244
2012 Xu LG, Jin L, Zhang BC, Akerlund LJ, Shu HB, Cambier JC. VISA is required for B cell expression of TLR7. Journal of Immunology (Baltimore, Md. : 1950). 188: 248-58. PMID 22105994 DOI: 10.4049/Jimmunol.1100918  0.243
2021 Zhong L, Shu HB. Mitotic inactivation of the cGAS‒MITA/STING pathways. Journal of Molecular Cell Biology. PMID 34609492 DOI: 10.1093/jmcb/mjab061  0.241
2019 Xu ZS, Zhang HX, Li WW, Ran Y, Liu TT, Xiong MG, Li QL, Wang SY, Wu M, Shu HB, Xia H, Wang YY. FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31061131 DOI: 10.1073/pnas.1814336116  0.24
2004 Huang J, Teng L, Li L, Liu T, Li L, Chen D, Xu LG, Zhai Z, Shu HB. ZNF216 Is an A20-like and IkappaB kinase gamma-interacting inhibitor of NFkappaB activation. The Journal of Biological Chemistry. 279: 16847-53. PMID 14754897 DOI: 10.1074/jbc.M309491200  0.234
2019 Hu MM, Shu HB. Innate Immune Response to Cytoplasmic DNA: Mechanisms and Diseases. Annual Review of Immunology. PMID 31800327 DOI: 10.1146/annurev-immunol-070119-115052  0.232
2002 Chen D, Li X, Zhai Z, Shu HB. A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1-induced NF-kappa B activation. The Journal of Biological Chemistry. 277: 15985-91. PMID 11854271 DOI: 10.1074/jbc.M108675200  0.232
2021 Liu R, Zeng LW, Gong R, Yuan F, Shu HB, Li S. mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis. Nature Communications. 12: 4227. PMID 34244482 DOI: 10.1038/s41467-021-24321-3  0.229
2009 ZHANG M, WANG R, WANG Y, DIAO F, LU F, GAO D, CHEN D, ZHAI Z, SHU H. The CXXC finger 5 protein is required for DNA damage-induced p53 activation. Science in China. Series C, Life Sciences. 52: 528-38. PMID 19557330 DOI: 10.1007/s11427-009-0083-7  0.228
2014 Zhang Y, Lei CQ, Hu YH, Xia T, Li M, Zhong B, Shu HB. Krüppel-like factor 6 is a co-activator of NF-κB that mediates p65-dependent transcription of selected downstream genes. The Journal of Biological Chemistry. 289: 12876-85. PMID 24634218 DOI: 10.1074/Jbc.M113.535831  0.224
2021 Lian H, Wei J, Zang R, Ye W, Yang Q, Zhang XN, Chen YD, Fu YZ, Hu MM, Lei CQ, Luo WW, Li S, Shu HB. Author Correction: ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response. Nature Communications. 12: 5526. PMID 34521835 DOI: 10.1038/s41467-021-25397-7  0.222
2021 Wang Z, Chen J, Gao C, Xiao Q, Wang XW, Tang SB, Li QL, Zhong B, Song ZY, Shu HB, Li LY, Wu M. Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100779. PMID 34363353 DOI: 10.1002/advs.202100779  0.22
2006 Cusick JK, Xu LG, Bin LH, Han KJ, Shu HB. Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1. Biochemical and Biophysical Research Communications. 340: 535-43. PMID 16389068 DOI: 10.1016/j.bbrc.2005.12.033  0.217
2021 Zhu Z, Wang G, Yang F, Cao W, Mao R, Du X, Zhang X, Li C, Li D, Zhang K, Shu H, Liu X, Zheng H. Erratum for Zhu et al., "Foot-and-Mouth Disease Virus Viroporin 2B Antagonizes RIG-I-Mediated Antiviral Effects by Inhibition of Its Protein Expression". Journal of Virology. 95: e0054521. PMID 34110266 DOI: 10.1128/JVI.00545-21  0.207
2008 Chen F, Du Y, Zhang Z, Chen G, Zhang M, Shu HB, Zhai Z, Chen D. Syntenin negatively regulates TRAF6-mediated IL-1R/TLR4 signaling. Cellular Signalling. 20: 666-74. PMID 18234474 DOI: 10.1016/J.Cellsig.2007.12.002  0.206
2004 Zhang J, Xu LG, Han KJ, Shu HB. Identification of a ZU5 and Death Domain-containing Inhibitor of NF-κB Journal of Biological Chemistry. 279: 17819-17825. PMID 14769797 DOI: 10.1074/jbc.M310737200  0.206
2017 Moua P, Checketts M, Xu LG, Shu HB, Reyland ME, Cusick J. RELT family members activate p38 and induce apoptosis by a mechanism distinct from TNFR1. Biochemical and Biophysical Research Communications. PMID 28688764 DOI: 10.1016/J.Bbrc.2017.07.022  0.203
2003 Li Z, Zhang J, Chen D, Shu HB. Casper/c-FLIP is physically and functionally associated with NF-kappaB1 p105. Biochemical and Biophysical Research Communications. 309: 980-5. PMID 13679070 DOI: 10.1016/j.bbrc.2003.08.104  0.202
2013 Kang X, Chen X, He Y, Guo D, Guo L, Zhong J, Shu HB. DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication. Virology. 435: 385-94. PMID 23137809 DOI: 10.1016/j.virol.2012.10.025  0.202
2012 Wang X, Zhu K, Li S, Liao Y, Du R, Zhang X, Shu HB, Guo AY, Li L, Wu M. MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB. Journal of Cell Science. 125: 4058-66. PMID 22623725 DOI: 10.1242/jcs.103531  0.201
2002 Xu LG, Wu M, Hu J, Zhai Z, Shu HB. Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1. Journal of Leukocyte Biology. 72: 410-6. PMID 12149433 DOI: 10.1189/Jlb.72.2.410  0.2
2014 Gong K, Zhang Z, Chen Y, Shu HB, Li W. Extracellular signal-regulated kinase, receptor interacting protein, and reactive oxygen species regulate shikonin-induced autophagy in human hepatocellular carcinoma European Journal of Pharmacology. 738: 142-152. PMID 24886888 DOI: 10.1016/j.ejphar.2014.05.034  0.2
2011 Wang L, Guo D, Xing B, Zhang JJ, Shu HB, Guo L, Huang XY. Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization. The Journal of Biological Chemistry. 286: 31055-61. PMID 21771786 DOI: 10.1074/Jbc.M111.253427  0.2
2020 Zhong L, Hu MM, Bian LJ, Liu Y, Chen Q, Shu HB. Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis. Cell Discovery. 6: 26. PMID 32351706 DOI: 10.1038/s41421-020-0162-2  0.198
2003 Bin LH, Xu LG, Shu HB. TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. The Journal of Biological Chemistry. 278: 24526-32. PMID 12721283 DOI: 10.1074/jbc.M303451200  0.192
2012 Liu LJ, Liu TT, Ran Y, Li Y, Zhang XD, Shu HB, Wang YY. The E3 ubiquitin ligase MIB1 negatively regulates basal IκBα level and modulates NF-κB activation. Cell Research. 22: 603-6. PMID 22184009 DOI: 10.1038/cr.2011.199  0.192
2018 Lin H, Gao D, Hu MM, Zhang M, Wu XX, Feng L, Xu WH, Yang Q, Zhong X, Wei J, Xu ZS, Zhang HX, Song ZM, Zhou Q, Ye W, ... ... Shu HB, et al. MARCH3 attenuates IL-1β-triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI. Proceedings of the National Academy of Sciences of the United States of America. PMID 30442668 DOI: 10.1073/pnas.1806217115  0.191
2023 Liu R, Zeng LW, Li HF, Shi JG, Zhong B, Shu HB, Li S. PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity. Cell Research. PMID 37932447 DOI: 10.1038/s41422-023-00890-4  0.191
2022 Yi XM, Li M, Chen YD, Shu HB, Li S. Reciprocal regulation of IL-33 receptor-mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38. Proceedings of the National Academy of Sciences of the United States of America. 119: e2116279119. PMID 35238669 DOI: 10.1073/pnas.2116279119  0.183
2008 Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB. GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Research. 18: 900-10. PMID 18591963 DOI: 10.1038/Cr.2008.75  0.181
2022 Zeng LW, Feng L, Liu R, Lin H, Shu HB, Li S. The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation. Cellular & Molecular Immunology. PMID 35982175 DOI: 10.1038/s41423-022-00907-9  0.178
2006 Huang J, Xu LG, Liu T, Zhai Z, Shu HB. The p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosis. Febs Letters. 580: 940-7. PMID 16427630 DOI: 10.1016/j.febslet.2005.09.105  0.176
2021 Lin H, Feng L, Cui KS, Zeng LW, Gao D, Zhang LX, Xu WH, Sun YH, Shu HB, Li S. The membrane-associated E3 ubiquitin ligase MARCH3 downregulates the IL-6 receptor and suppresses colitis-associated carcinogenesis. Cellular & Molecular Immunology. PMID 34785732 DOI: 10.1038/s41423-021-00799-1  0.172
2002 Bin L, Li X, Xu LG, Shu HB. The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis. Febs Letters. 510: 37-40. PMID 11755527  0.163
2020 Li D, Fu S, Wu Z, Yang W, Ru Y, Shu H, Liu X, Zheng H. Correction: DDX56 inhibits type I interferon by disrupting assembly of IRF3-IPO5 to inhibit IRF3 nucleus import. Journal of Cell Science. 133. PMID 32079732 DOI: 10.1242/jcs.244681  0.158
2003 Xu LG, Shu HB. TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production. Journal of Immunology (Baltimore, Md. : 1950). 169: 6883-9. PMID 12471121 DOI: 10.4049/jimmunol.169.12.6883  0.157
2008 Wang RP, Zhang M, Li Y, Diao FC, Chen D, Zhai Z, Shu HB. Differential regulation of IKK alpha-mediated activation of IRF3/7 by NIK. Molecular Immunology. 45: 1926-34. PMID 18068231 DOI: 10.1016/j.molimm.2007.10.034  0.156
2013 Li C, Wei J, Li Y, He X, Zhou Q, Yan J, Zhang J, Liu Y, Liu Y, Shu HB. Transmembrane Protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase 4 enzyme activation and apoptosis. The Journal of Biological Chemistry. 288: 17908-17. PMID 23661706 DOI: 10.1074/Jbc.M113.458836  0.154
2022 Yang Z, Liang H, Zhou Q, Li Y, Chen H, Ye W, Chen D, Fleming J, Shu H, Liu Y. Author Correction: Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. Cell Research. PMID 35585185 DOI: 10.1038/s41422-022-00660-8  0.153
2008 Li L, Hailey DW, Soetandyo N, Li W, Lippincott-Schwartz J, Shu HB, Ye Y. Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling. Biochimica Et Biophysica Acta. 1783: 1140-9. PMID 18329387 DOI: 10.1016/J.Bbamcr.2008.01.029  0.15
2009 Xiong L, Zhao T, Huang X, Liu ZH, Zhao H, Li MM, Wu LY, Shu HB, Zhu LL, Fan M. Heat shock protein 90 is involved in regulation of hypoxia-driven proliferation of embryonic neural stem/progenitor cells. Cell Stress & Chaperones. 14: 183-92. PMID 18726712 DOI: 10.1007/s12192-008-0071-z  0.145
2022 Feng L, Li C, Zeng LW, Gao D, Sun YH, Zhong L, Lin H, Shu HB, Li S. MARCH3 negatively regulates IL-3-triggered inflammatory response by mediating K48-linked polyubiquitination and degradation of IL-3Rα. Signal Transduction and Targeted Therapy. 7: 21. PMID 35075102 DOI: 10.1038/s41392-021-00834-7  0.143
2004 Wu M, Xu LG, Su T, Tian Y, Zhai Z, Shu HB. AMID is a p53-inducible gene downregulated in tumors. Oncogene. 23: 6815-9. PMID 15273740 DOI: 10.1038/sj.onc.1207909  0.142
2002 Wu M, Xu LG, Li X, Zhai Z, Shu HB. AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis. The Journal of Biological Chemistry. 277: 25617-23. PMID 11980907 DOI: 10.1074/jbc.M202285200  0.137
2004 Lesley R, Xu Y, Kalled SL, Hess DM, Schwab SR, Shu HB, Cyster JG. Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity. 20: 441-53. PMID 15084273 DOI: 10.1016/S1074-7613(04)00079-2  0.134
2003 Bin LH, Nielson LD, Liu X, Mason RJ, Shu HB. Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. Journal of Immunology (Baltimore, Md. : 1950). 171: 924-30. PMID 12847263 DOI: 10.4049/jimmunol.171.2.924  0.132
2020 Xie T, Chen T, Li C, Wang W, Cao L, Rao H, Yang Q, Shu HB, Xu LG. Corrigendum to "RACK1 attenuates RLR antiviral signaling by targeting VISA-TRAF complexes" [Biochem. Biophys. Res. Commun. 508(3) (2019) 667-674]. Biochemical and Biophysical Research Communications. PMID 33243463 DOI: 10.1016/j.bbrc.2020.11.045  0.131
2012 Wu M, Shu HB. MLL1/WDR5 complex in leukemogenesis and epigenetic regulation. Chinese Journal of Cancer. 30: 240-6. PMID 21439245 DOI: 10.5732/cjc.011.10055  0.129
2010 Yi H, Xue L, Guo MX, Ma J, Zeng Y, Wang W, Cai JY, Hu HM, Shu HB, Shi YB, Li WX. Gene expression atlas for human embryogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3341-50. PMID 20430792 DOI: 10.1096/fj.10-158782  0.122
2003 Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L, Pan CH, Martin WE, Murphy RC, Shu HB, Dai S, Zhang G. Ligand-receptor binding revealed by the TNF family member TALL-1 Nature. 423: 49-56. PMID 12721620 DOI: 10.1038/Nature01543  0.12
2022 Xiong W, Gao X, Zhang T, Jiang B, Hu MM, Bu X, Gao Y, Zhang LZ, Xiao BL, He C, Sun Y, Li H, Shi J, Xiao X, Xiang B, ... ... Shu HB, et al. USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy. Nature Communications. 13: 1700. PMID 35361799 DOI: 10.1038/s41467-022-29401-6  0.087
2016 Rong L, Zhang C, Lei Q, Hu MM, Feng J, Shu HB, Liu Y, Zhang XZ. Hydrogen peroxide detection with high specificity in living cells and inflamed tissues. Regenerative Biomaterials. 3: 217-22. PMID 27482463 DOI: 10.1093/Rb/Rbw022  0.081
2010 Ji Y, Qin Y, Shu H, Li X. Methylation analyses on promoters of mPer1, mPer2, and mCry1 during perinatal development. Biochemical and Biophysical Research Communications. 391: 1742-7. PMID 20043880 DOI: 10.1016/j.bbrc.2009.12.146  0.065
2022 Shu HB. Cell Insight: An exciting new channel looking into life and diseases. Cell Insight. 1: 100006. PMID 37192985 DOI: 10.1016/j.cellin.2022.100006  0.045
2014 Shu HB, Wang YY. Adding to the STING. Immunity. 41: 871-3. PMID 25526298 DOI: 10.1016/j.immuni.2014.12.002  0.01
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