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Jakob Helmuth von Moltke - Publications

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, Chen Z, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Wu C, ... ... von Moltke J, et al. Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance. Immunity. PMID 38744291 DOI: 10.1016/j.immuni.2024.03.023  0.505
2024 Kasal DN, Warner L, Bryant A, Tait-Wojno E, von Moltke J. Systemic Immune Modulation by Gastrointestinal Nematodes. Annual Review of Immunology. PMID 38277692 DOI: 10.1146/annurev-immunol-090222-101331  0.342
2023 Nadjsombati MS, Niepoth N, Webeck LM, Kennedy EA, Jones DL, Billipp TE, Baldridge MT, Bendesky A, von Moltke J. Genetic mapping reveals OCA-T1-dependent tuning of tuft cell differentiation and intestinal type 2 immunity. Science Immunology. 8: eade5019. PMID 37172102 DOI: 10.1126/sciimmunol.ade5019  0.456
2023 Billipp TE, Fung C, Webeck LM, Sargent DB, Gologorsky MB, McDaniel MM, Kasal DN, McGinty JW, Barrow KA, Rich LM, Barilli A, Sabat M, Debley JS, Myers R, Howitt MR, ... von Moltke J, et al. Tuft cell-derived acetylcholine regulates epithelial fluid secretion. Biorxiv : the Preprint Server For Biology. PMID 36993541 DOI: 10.1101/2023.03.17.533208  0.492
2023 McDaniel MM, Lara HI, von Moltke J. Initiation of type 2 immunity at barrier surfaces. Mucosal Immunology. PMID 36642383 DOI: 10.1016/j.mucimm.2022.11.002  0.345
2022 Barr J, Gentile ME, Lee S, Kotas ME, Fernanda de Mello Costa M, Holcomb NP, Jaquish A, Palashikar G, Soewignjo M, McDaniel M, Matsumoto I, Margolskee R, Von Moltke J, Cohen NA, Sun X, et al. Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair. Elife. 11. PMID 36073526 DOI: 10.7554/eLife.78074  0.341
2022 Karo-Atar D, Ouladan S, Javkar T, Joumier L, Matheson MK, Merritt S, Westfall S, Rochette A, Gentile ME, Fontes G, Fonseca GJ, Parisien M, Diatchenko L, von Moltke J, Malleshaiah M, et al. Helminth-induced reprogramming of the stem cell compartment inhibits type 2 immunity. The Journal of Experimental Medicine. 219. PMID 35938990 DOI: 10.1084/jem.20212311  0.37
2022 Zhao M, Ren K, Xiong X, Xin Y, Zou Y, Maynard JC, Kim A, Battist AP, Koneripalli N, Wang Y, Chen Q, Xin R, Yang C, Huang R, Yu J, ... ... von Moltke J, et al. Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. Immunity. 55: 623-638.e5. PMID 35385697 DOI: 10.1016/j.immuni.2022.03.009  0.448
2022 O'Leary CE, Sbierski-Kind J, Kotas ME, Wagner JC, Liang HE, Schroeder AW, de Tenorio JC, von Moltke J, Ricardo-Gonzalez RR, Eckalbar WL, Molofsky AB, Schneider C, Locksley RM. Bile acid-sensitive tuft cells regulate biliary neutrophil influx. Science Immunology. 7: eabj1080. PMID 35245089 DOI: 10.1126/sciimmunol.abj1080  0.601
2021 Oyesola OO, Shanahan MT, Kanke M, Mooney BM, Webb LM, Smita S, Matheson MK, Campioli P, Pham D, Früh SP, McGinty JW, Churchill MJ, Cahoon JL, Sundaravaradan P, Flitter BA, ... ... von Moltke J, et al. PGD2 and CRTH2 counteract Type 2 cytokine-elicited intestinal epithelial responses during helminth infection. The Journal of Experimental Medicine. 218. PMID 34283207 DOI: 10.1084/jem.20202178  0.77
2020 Billipp TE, Nadjsombati MS, von Moltke J. Tuning tuft cells: new ligands and effector functions reveal tissue-specific function. Current Opinion in Immunology. 68: 98-106. PMID 33166855 DOI: 10.1016/j.coi.2020.09.006  0.43
2020 McGinty JW, Ting HA, Billipp TE, Nadjsombati MS, Khan DM, Barrett NA, Liang HE, Matsumoto I, von Moltke J. Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity. PMID 32160525 DOI: 10.1016/j.immuni.2020.02.005  0.548
2019 McGinty JW, von Moltke J. A three course menu for ILC and bystander T cell activation. Current Opinion in Immunology. 62: 15-21. PMID 31830683 DOI: 10.1016/j.coi.2019.11.005  0.307
2019 Forero A, Ozarkar S, Li H, Lee CH, Hemann EA, Nadjsombati MS, Hendricks MR, So L, Green R, Roy CN, Sarkar SN, von Moltke J, Anderson SK, Gale M, Savan R. Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons. Immunity. PMID 31471108 DOI: 10.1016/J.Immuni.2019.07.007  0.359
2019 Ting HA, von Moltke J. The Immune Function of Tuft Cells at Gut Mucosal Surfaces and Beyond. Journal of Immunology (Baltimore, Md. : 1950). 202: 1321-1329. PMID 30782851 DOI: 10.4049/jimmunol.1801069  0.424
2018 Bankova LG, Dwyer DF, Yoshimoto E, Ualiyeva S, McGinty JW, Raff H, von Moltke J, Kanaoka Y, Frank Austen K, Barrett NA. The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation. Science Immunology. 3. PMID 30291131 DOI: 10.1126/sciimmunol.aat9453  0.43
2018 Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, et al. Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. PMID 30022164 DOI: 10.1038/S41586-018-0345-2  0.616
2018 Nadjsombati MS, McGinty JW, Lyons-Cohen MR, Jaffe JB, DiPeso L, Schneider C, Miller CN, Pollack JL, Nagana Gowda GA, Fontana MF, Erle DJ, Anderson MS, Locksley RM, Raftery D, von Moltke J. Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit. Immunity. 49: 33-41.e7. PMID 30021144 DOI: 10.1016/J.Immuni.2018.06.016  0.794
2018 Schneider C, O'Leary CE, von Moltke J, Liang HE, Ang QY, Turnbaugh PJ, Radhakrishnan S, Pellizzon M, Ma A, Locksley RM. A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling. Cell. PMID 29887373 DOI: 10.1016/J.Cell.2018.05.014  0.648
2018 Banerjee A, McKinley ET, von Moltke J, Coffey RJ, Lau KS. Interpreting heterogeneity in intestinal tuft cell structure and function. The Journal of Clinical Investigation. 128: 1711-1719. PMID 29714721 DOI: 10.1172/JCI120330  0.423
2018 von Moltke J, Pepper M. Sentinels of the Type 2 Immune Response. Trends in Immunology. 39: 99-111. PMID 29122456 DOI: 10.1016/J.It.2017.10.004  0.42
2017 Nichols RD, von Moltke J, Vance RE. NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease. Nature Communications. 8: 2209. PMID 29263322 DOI: 10.1038/S41467-017-02266-W  0.7
2017 Singh PB, Pua HH, Happ HC, Schneider C, von Moltke J, Locksley RM, Baumjohann D, Ansel KM. MicroRNA regulation of type 2 innate lymphoid cell homeostasis and function in allergic inflammation. The Journal of Experimental Medicine. PMID 29122948 DOI: 10.1084/Jem.20170545  0.55
2017 Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. PMID 28410991 DOI: 10.1016/J.Immuni.2017.03.016  0.646
2016 von Moltke J, O'Leary CE, Barrett NA, Kanaoka Y, Austen KF, Locksley RM. Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. The Journal of Experimental Medicine. PMID 28011865 DOI: 10.1084/Jem.20161274  0.639
2015 von Moltke J, Ji M, Liang HE, Locksley RM. Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature. PMID 26675736 DOI: 10.1038/Nature16161  0.704
2014 von Moltke J, Locksley RM. I-L-C-2 it: type 2 immunity and group 2 innate lymphoid cells in homeostasis. Current Opinion in Immunology. 31: 58-65. PMID 25458996 DOI: 10.1016/J.Coi.2014.09.009  0.666
2013 Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 502: 245-8. PMID 24037376 DOI: 10.1038/Nature12526  0.775
2013 von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. Recognition of bacteria by inflammasomes. Annual Review of Immunology. 31: 73-106. PMID 23215645 DOI: 10.1146/Annurev-Immunol-032712-095944  0.741
2012 von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, Vance RE. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature. 490: 107-11. PMID 22902502 DOI: 10.1038/Nature11351  0.742
2011 Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infection and Immunity. 79: 688-94. PMID 21098106 DOI: 10.1128/Iai.00999-10  0.788
2010 Broz P, von Moltke J, Jones JW, Vance RE, Monack DM. Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host & Microbe. 8: 471-83. PMID 21147462 DOI: 10.1016/J.Chom.2010.11.007  0.745
2008 Lightfield KL, Persson J, Brubaker SW, Witte CE, von Moltke J, Dunipace EA, Henry T, Sun YH, Cado D, Dietrich WF, Monack DM, Tsolis RM, Vance RE. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nature Immunology. 9: 1171-8. PMID 18724372 DOI: 10.1038/Ni.1646  0.684
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