| Year |
Citation |
Score |
| 2019 |
Goodrum JM, Lever AR, Coody TK, Gottschling DE, Hughes AL. Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress. Molecular Biology of the Cell. mbcE19020094. PMID 31141470 DOI: 10.1091/Mbc.E19-02-0094 |
0.326 |
|
| 2016 |
Hughes AL, Hughes CE, Henderson KA, Yazvenko N, Gottschling DE. Author response: Selective sorting and destruction of mitochondrial membrane proteins in aged yeast Elife. DOI: 10.7554/Elife.13943.023 |
0.303 |
|
| 2014 |
Thayer NH, Leverich CK, Fitzgibbon MP, Nelson ZW, Henderson KA, Gafken PR, Hsu JJ, Gottschling DE. Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions. Proceedings of the National Academy of Sciences of the United States of America. 111: 14019-26. PMID 25228775 DOI: 10.1073/Pnas.1416079111 |
0.389 |
|
| 2014 |
Dillin A, Gottschling DE, Nyström T. The good and the bad of being connected: the integrons of aging. Current Opinion in Cell Biology. 26: 107-12. PMID 24529252 DOI: 10.1016/J.Ceb.2013.12.003 |
0.319 |
|
| 2012 |
Hughes AL, Gottschling DE. An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature. 492: 261-5. PMID 23172144 DOI: 10.1038/Nature11654 |
0.351 |
|
| 2011 |
Dymond JS, Richardson SM, Coombes CE, Babatz T, Muller H, Annaluru N, Blake WJ, Schwerzmann JW, Dai J, Lindstrom DL, Boeke AC, Gottschling DE, Chandrasegaran S, Bader JS, Boeke JD. Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 477: 471-6. PMID 21918511 DOI: 10.1038/Nature10403 |
0.396 |
|
| 2011 |
Lindstrom DL, Leverich CK, Henderson KA, Gottschling DE. Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. Plos Genetics. 7: e1002015. PMID 21436897 DOI: 10.1371/Journal.Pgen.1002015 |
0.479 |
|
| 2010 |
Verzijlbergen KF, Menendez-Benito V, van Welsem T, van Deventer SJ, Lindstrom DL, Ovaa H, Neefjes J, Gottschling DE, van Leeuwen F. Recombination-induced tag exchange to track old and new proteins. Proceedings of the National Academy of Sciences of the United States of America. 107: 64-8. PMID 20018668 DOI: 10.1073/Pnas.0911164107 |
0.303 |
|
| 2009 |
Lindstrom DL, Gottschling DE. The mother enrichment program: a genetic system for facile replicative life span analysis in Saccharomyces cerevisiae. Genetics. 183: 413-22, 1SI-13SI. PMID 19652178 DOI: 10.1534/Genetics.109.106229 |
0.366 |
|
| 2009 |
Dimitrov LN, Brem RB, Kruglyak L, Gottschling DE. Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics. 183: 365-83. PMID 19581448 DOI: 10.1534/Genetics.109.104497 |
0.339 |
|
| 2009 |
Veatch JR, McMurray MA, Nelson ZW, Gottschling DE. Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell. 137: 1247-58. PMID 19563757 DOI: 10.1016/J.Cell.2009.04.014 |
0.655 |
|
| 2008 |
Henderson KA, Gottschling DE. A mother's sacrifice: what is she keeping for herself? Current Opinion in Cell Biology. 20: 723-8. PMID 18848886 DOI: 10.1016/J.Ceb.2008.09.004 |
0.391 |
|
| 2008 |
Andersen MP, Nelson ZW, Hetrick ED, Gottschling DE. A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae. Genetics. 179: 1179-95. PMID 18562670 DOI: 10.1534/Genetics.108.089250 |
0.407 |
|
| 2008 |
van Welsem T, Frederiks F, Verzijlbergen KF, Faber AW, Nelson ZW, Egan DA, Gottschling DE, van Leeuwen F. Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core. Molecular and Cellular Biology. 28: 3861-72. PMID 18391024 DOI: 10.1128/Mcb.02050-07 |
0.36 |
|
| 2008 |
Carr LL, Gottschling DE. Does age influence loss of heterozygosity? Experimental Gerontology. 43: 123-9. PMID 18054191 DOI: 10.1016/J.Exger.2007.10.010 |
0.412 |
|
| 2006 |
Gottschling DE. DNA repair: corrections in the golden years. Current Biology : Cb. 16: R956-8. PMID 17113375 DOI: 10.1016/J.Cub.2006.10.016 |
0.388 |
|
| 2005 |
Gardner RG, Nelson ZW, Gottschling DE. Ubp10/Dot4p regulates the persistence of ubiquitinated histone H2B: distinct roles in telomeric silencing and general chromatin. Molecular and Cellular Biology. 25: 6123-39. PMID 15988024 DOI: 10.1128/Mcb.25.14.6123-6139.2005 |
0.374 |
|
| 2005 |
Gardner RG, Nelson ZW, Gottschling DE. Degradation-mediated protein quality control in the nucleus. Cell. 120: 803-15. PMID 15797381 DOI: 10.1016/J.Cell.2005.01.016 |
0.311 |
|
| 2005 |
Xu EY, Bi X, Holland MJ, Gottschling DE, Broach JR. Mutations in the nucleosome core enhance transcriptional silencing. Molecular and Cellular Biology. 25: 1846-59. PMID 15713639 DOI: 10.1128/Mcb.25.5.1846-1859.2005 |
0.325 |
|
| 2005 |
Koschwanez J, Holl M, Carlson R, McMurray M, Gottschling D, Meldrum D. Automated lifetime analysis of a single yeast cell Proceedings of the 2005 Ieee Conference On Automation Science and Engineering, Ieee-Case 2005. 2005: 13-18. DOI: 10.1109/COASE.2005.1506738 |
0.62 |
|
| 2004 |
McMurray MA, Gottschling DE. Genetic instability in aging yeast: a metastable hyperrecombinational state. Cold Spring Harbor Symposia On Quantitative Biology. 69: 339-47. PMID 16117666 DOI: 10.1101/Sqb.2004.69.339 |
0.644 |
|
| 2004 |
McMurray MA, Gottschling DE. Aging and genetic instability in yeast. Current Opinion in Microbiology. 7: 673-9. PMID 15556042 DOI: 10.1016/J.Mib.2004.10.008 |
0.691 |
|
| 2004 |
Schübeler D, MacAlpine DM, Scalzo D, Wirbelauer C, Kooperberg C, van Leeuwen F, Gottschling DE, O'Neill LP, Turner BM, Delrow J, Bell SP, Groudine M. The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes & Development. 18: 1263-71. PMID 15175259 DOI: 10.1101/Gad.1198204 |
0.342 |
|
| 2004 |
Koschwanez J, Holl M, McMurray M, Gottschling D, Meldrum D. Automation of yeast pedigree analysis Proceedings - Ieee International Conference On Robotics and Automation. 2004: 1475-1480. |
0.616 |
|
| 2003 |
McMurray MA, Gottschling DE. An age-induced switch to a hyper-recombinational state. Science (New York, N.Y.). 301: 1908-11. PMID 14512629 DOI: 10.1126/Science.1087706 |
0.674 |
|
| 2003 |
Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes & Development. 17: 2384-95. PMID 12975323 DOI: 10.1101/Gad.1125903 |
0.407 |
|
| 2003 |
van Leeuwen F, Gottschling DE. The histone minority report: the variant shall not be silenced. Cell. 112: 591-3. PMID 12628179 DOI: 10.1016/S0092-8674(03)00152-1 |
0.314 |
|
| 2002 |
van Leeuwen F, Gottschling DE. Genome-wide histone modifications: gaining specificity by preventing promiscuity. Current Opinion in Cell Biology. 14: 756-62. PMID 12473351 DOI: 10.1016/S0955-0674(02)00393-9 |
0.367 |
|
| 2002 |
Smith CM, Haimberger ZW, Johnson CO, Wolf AJ, Gafken PR, Zhang Z, Parthun MR, Gottschling DE. Heritable chromatin structure: mapping "memory" in histones H3 and H4. Proceedings of the National Academy of Sciences of the United States of America. 99: 16454-61. PMID 12196632 DOI: 10.1073/Pnas.182424999 |
0.328 |
|
| 2002 |
van Leeuwen F, Gafken PR, Gottschling DE. Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell. 109: 745-56. PMID 12086673 DOI: 10.1016/S0092-8674(02)00759-6 |
0.309 |
|
| 2002 |
van Leeuwen F, Gottschling DE. Assays for gene silencing in yeast. Methods in Enzymology. 350: 165-86. PMID 12073311 DOI: 10.1016/S0076-6879(02)50962-9 |
0.453 |
|
| 2001 |
Bedalov A, Gatbonton T, Irvine WP, Gottschling DE, Simon JA. Identification of a small molecule inhibitor of Sir2p. Proceedings of the National Academy of Sciences of the United States of America. 98: 15113-8. PMID 11752457 DOI: 10.1073/Pnas.261574398 |
0.391 |
|
| 2001 |
Diede SJ, Gottschling DE. Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere. Current Biology : Cb. 11: 1336-40. PMID 11553326 DOI: 10.1016/S0960-9822(01)00400-6 |
0.393 |
|
| 2000 |
Gottschling DE. Gene silencing: two faces of SIR2. Current Biology : Cb. 10: R708-11. PMID 11050406 DOI: 10.1016/S0960-9822(00)00714-4 |
0.353 |
|
| 2000 |
Kelly TJ, Qin S, Gottschling DE, Parthun MR. Type B histone acetyltransferase Hat1p participates in telomeric silencing. Molecular and Cellular Biology. 20: 7051-8. PMID 10982821 DOI: 10.1128/Mcb.20.19.7051-7058.2000 |
0.34 |
|
| 1999 |
Diede SJ, Gottschling DE. Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell. 99: 723-33. PMID 10619426 DOI: 10.1016/S0092-8674(00)81670-0 |
0.389 |
|
| 1999 |
Kahana A, Gottschling DE. DOT4 links silencing and cell growth in Saccharomyces cerevisiae. Molecular and Cellular Biology. 19: 6608-20. PMID 10490600 DOI: 10.1128/Mcb.19.10.6608 |
0.375 |
|
| 1999 |
Gottschling DE, Stoddard B. Telomeres: structure of a chromosome's aglet. Current Biology : Cb. 9: R164-7. PMID 10074444 DOI: 10.1016/S0960-9822(99)80103-1 |
0.372 |
|
| 1999 |
Stevenson JB, Gottschling DE. Telomeric chromatin modulates replication timing near chromosome ends. Genes & Development. 13: 146-51. PMID 9925638 DOI: 10.1101/Gad.13.2.146 |
0.431 |
|
| 1998 |
Gottschling DE, Berg BL. Chromosome dynamics: yeast pulls it apart. Current Biology : Cb. 8: R76-9. PMID 9443905 DOI: 10.1016/S0960-9822(98)70050-8 |
0.364 |
|
| 1997 |
Huang H, Kahana A, Gottschling DE, Prakash L, Liebman SW. The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae. Molecular and Cellular Biology. 17: 6693-9. PMID 9343433 DOI: 10.1128/Mcb.17.11.6693 |
0.394 |
|
| 1994 |
Sandell LL, Gottschling DE, Zakian VA. Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability. Proceedings of the National Academy of Sciences of the United States of America. 91: 12061-5. PMID 7991584 DOI: 10.1073/Pnas.91.25.12061 |
0.597 |
|
| 1994 |
Aparicio OM, Gottschling DE. Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. Genes & Development. 8: 1133-46. PMID 7926719 DOI: 10.1101/Gad.8.10.1133 |
0.392 |
|
| 1994 |
Singer MS, Gottschling DE. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science (New York, N.Y.). 266: 404-9. PMID 7545955 DOI: 10.1126/Science.7545955 |
0.42 |
|
| 1993 |
Renauld H, Aparicio OM, Zierath PD, Billington BL, Chhablani SK, Gottschling DE. Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes & Development. 7: 1133-45. PMID 8319906 DOI: 10.1101/Gad.7.7A.1133 |
0.409 |
|
| 1992 |
Wright JH, Gottschling DE, Zakian VA. Saccharomyces telomeres assume a non-nucleosomal chromatin structure. Genes & Development. 6: 197-210. PMID 1737616 DOI: 10.1101/Gad.6.2.197 |
0.612 |
|
| 1992 |
Gottschling DE. Telomere-proximal DNA in Saccharomyces cerevisiae is refractory to methyltransferase activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 89: 4062-5. PMID 1570334 DOI: 10.1073/Pnas.89.9.4062 |
0.432 |
|
| 1991 |
Aparicio OM, Billington BL, Gottschling DE. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell. 66: 1279-87. PMID 1913809 DOI: 10.1016/0092-8674(91)90049-5 |
0.41 |
|
| 1990 |
Gottschling DE, Aparicio OM, Billington BL, Zakian VA. Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell. 63: 751-62. PMID 2225075 DOI: 10.1016/0092-8674(90)90141-Z |
0.599 |
|
| 1988 |
Gottschling DE, Zakian VA. Dna-Protein Interactions at Telomeres in Ciliated Protozoans Advances in Molecular and Cell Biology. 2: 291-307. DOI: 10.1016/S1569-2558(08)60438-5 |
0.598 |
|
| 1986 |
Gottschling DE, Zakian VA. Telomere proteins: specific recognition and protection of the natural termini of Oxytricha macronuclear DNA. Cell. 47: 195-205. PMID 3094961 DOI: 10.1016/0092-8674(86)90442-3 |
0.583 |
|
| 1984 |
Gottschling DE, Cech TR. Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex. Cell. 38: 501-10. PMID 6432344 DOI: 10.1016/0092-8674(84)90505-1 |
0.522 |
|
| 1983 |
Gottschling DE, Palen TE, Cech TR. Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene in Tetrahymena thermophila. Nucleic Acids Research. 11: 2093-109. PMID 6835846 DOI: 10.1093/Nar/11.7.2093 |
0.524 |
|
| 1982 |
Kruger K, Grabowski PJ, Zaug AJ, Sands J, Gottschling DE, Cech TR. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell. 31: 147-57. PMID 6297745 DOI: 10.1016/0092-8674(82)90414-7 |
0.459 |
|
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