| Year |
Citation |
Score |
| 2023 |
Hwang SM, Awasthi D, Jeong J, Sandoval TA, Chae CS, Ramos Y, Tan C, Falco MM, McBain IT, Mishra B, Ivashkiv LB, Zamarin D, Cantillo E, Chapman-Davis E, Holcomb K, ... ... Cubillos-Ruiz JR, et al. Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function. Research Square. PMID 38168227 DOI: 10.21203/rs.3.rs-3683989/v1 |
0.711 |
|
| 2023 |
Smolgovsky S, Bayer AL, Kaur K, Sanders E, Aronovitz M, Filipp ME, Thorp EB, Schiattarella GG, Hill JA, Blanton RM, Cubillos-Ruiz JR, Alcaide P. Impaired T cell IRE1α-XBP1 signaling directs inflammation in experimental Heart Failure with Preserved Ejection Fraction. The Journal of Clinical Investigation. PMID 37874641 DOI: 10.1172/JCI171874 |
0.308 |
|
| 2023 |
Markowitz GJ, Ban Y, Tavarez DA, Yoffe L, Podaza E, He Y, Martin MT, Crowley MJP, Sandoval TA, Gao D, Martin ML, Elemento O, Cubillos-Ruiz JR, McGraw TE, Altorki NK, et al. Deficiency of metabolic regulator PKM2 activates the pentose phosphate pathway and generates TCF1+ progenitor CD8+ T cells to improve checkpoint blockade. Research Square. PMID 37790365 DOI: 10.21203/rs.3.rs-3356477/v1 |
0.457 |
|
| 2023 |
Di Conza G, Ho PC, Cubillos-Ruiz JR, Huang SC. Control of immune cell function by the unfolded protein response. Nature Reviews. Immunology. PMID 36755160 DOI: 10.1038/s41577-023-00838-0 |
0.333 |
|
| 2023 |
Crowley MJP, Bhinder B, Markowitz GJ, Martin M, Verma A, Sandoval TA, Chae CS, Yomtoubian S, Hu Y, Chopra S, Tavarez DA, Giovanelli P, Gao D, McGraw TE, Altorki NK, ... ... Cubillos-Ruiz JR, et al. Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer. Nature Communications. 14: 120. PMID 36624093 DOI: 10.1038/s41467-022-35584-9 |
0.504 |
|
| 2022 |
Mandula JK, Chang S, Mohamed E, Jimenez R, Sierra-Mondragon RA, Chang DC, Obermayer AN, Moran-Segura CM, Das S, Vazquez-Martinez JA, Prieto K, Chen A, Smalley KSM, Czerniecki B, Forsyth P, ... ... Cubillos-Ruiz JR, et al. Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses. Cancer Cell. PMID 36150390 DOI: 10.1016/j.ccell.2022.08.016 |
0.745 |
|
| 2022 |
Salvagno C, Mandula JK, Rodriguez PC, Cubillos-Ruiz JR. Decoding endoplasmic reticulum stress signals in cancer cells and antitumor immunity. Trends in Cancer. PMID 35817701 DOI: 10.1016/j.trecan.2022.06.006 |
0.38 |
|
| 2022 |
Chae CS, Sandoval TA, Hwang SM, Park ES, Giovanelli P, Awasthi D, Salvagno C, Emmanuelli A, Tan C, Chaudhary V, Casado J, Kossenkov AV, Song M, Barrat FJ, Holcomb K, ... ... Cubillos-Ruiz JR, et al. Tumor-derived Lysophosphatidic Acid Blunts Protective Type-I Interferon Responses in Ovarian Cancer. Cancer Discovery. PMID 35552618 DOI: 10.1158/2159-8290.CD-21-1181 |
0.487 |
|
| 2022 |
Paffenholz SV, Salvagno C, Ho YJ, Limjoco M, Baslan T, Tian S, Kulick A, de Stanchina E, Wilkinson JE, Barriga FM, Zamarin D, Cubillos-Ruiz JR, Leibold J, Lowe SW. Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35082152 DOI: 10.1073/pnas.2117754119 |
0.409 |
|
| 2022 |
Cubillos-Ruiz JR, Cubillos-Ruiz A. Engineered bacteria recycle tumor metabolic waste to boost immunotherapy. Cell Host & Microbe. 29: 1725-1727. PMID 34883059 DOI: 10.1016/j.chom.2021.11.008 |
0.422 |
|
| 2021 |
Salvagno C, Cubillos-Ruiz JR. Optineurin Guards IFNγ Signaling in Cancer Cells. Cancer Discovery. 11: 1623-1625. PMID 34284996 DOI: 10.1158/2159-8290.CD-21-0362 |
0.384 |
|
| 2020 |
Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, ... ... Cubillos-Ruiz JR, et al. BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. Science (New York, N.Y.). 369: 942-949. PMID 32820120 DOI: 10.1126/Science.Aay2767 |
0.762 |
|
| 2020 |
Mohamed E, Sierra RA, Trillo-Tinoco J, Cao Y, Innamarato P, Payne KK, de Mingo Pulido A, Mandula J, Zhang S, Thevenot P, Biswas S, Abdalla SK, Costich TL, Hänggi K, Anadon CM, ... ... Cubillos-Ruiz JR, et al. The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 52: 668-682.e7. PMID 32294407 DOI: 10.1016/J.Immuni.2020.03.004 |
0.75 |
|
| 2020 |
Cubillos-Ruiz JR. Abstract IA16: ER stress responses shape the ovarian cancer immune-microenvironment Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-Ia16 |
0.612 |
|
| 2020 |
Zhou ZN, Sandoval TA, Chae CS, Cubillos-Ruiz JR. IRE1α-XBP1 Signaling as a Mechanism of Resistance to Immunotherapy in Ovarian Cancer Gynecologic Oncology. 158. DOI: 10.1016/J.Ygyno.2020.04.003 |
0.338 |
|
| 2019 |
Salvagno C, Cubillos-Ruiz JR. The impact of endoplasmic reticulum stress responses in dendritic cell immunobiology. International Review of Cell and Molecular Biology. 349: 153-176. PMID 31759430 DOI: 10.1016/Bs.Ircmb.2019.08.004 |
0.526 |
|
| 2019 |
Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, ... Cubillos-Ruiz JR, et al. Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 3680. PMID 31417079 DOI: 10.1038/S41467-019-11563-5 |
0.662 |
|
| 2019 |
Giovanelli P, Sandoval TA, Cubillos-Ruiz JR. Dendritic Cell Metabolism and Function in Tumors. Trends in Immunology. 40: 699-718. PMID 31301952 DOI: 10.1016/J.It.2019.06.004 |
0.592 |
|
| 2019 |
Nam AS, Kim KT, Chaligne R, Izzo F, Ang C, Taylor J, Myers RM, Abu-Zeinah G, Brand R, Omans ND, Alonso A, Sheridan C, Mariani M, Dai X, Harrington E, ... ... Cubillos-Ruiz JR, et al. Somatic mutations and cell identity linked by Genotyping of Transcriptomes. Nature. PMID 31270458 DOI: 10.1038/S41586-019-1367-0 |
0.377 |
|
| 2019 |
Márquez S, Fernández JJ, Mancebo C, Herrero-Sánchez C, Alonso S, Sandoval TA, Rodríguez Prados M, Cubillos-Ruiz JR, Montero O, Fernández N, Sánchez Crespo M. Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns. Cell Reports. 27: 525-536.e4. PMID 30970255 DOI: 10.1016/J.Celrep.2019.03.033 |
0.305 |
|
| 2019 |
Cao Y, Trillo-Tinoco J, Sierra RA, Anadon C, Dai W, Mohamed E, Cen L, Costich TL, Magliocco A, Marchion D, Klar R, Michel S, Jaschinski F, Reich RR, Mehrotra S, ... Cubillos-Ruiz JR, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nature Communications. 10: 1280. PMID 30894532 DOI: 10.1038/S41467-019-09263-1 |
0.751 |
|
| 2019 |
Song M, Cubillos-Ruiz JR. Endoplasmic Reticulum Stress Responses in Intratumoral Immune Cells: Implications for Cancer Immunotherapy. Trends in Immunology. 40: 128-141. PMID 30612925 DOI: 10.1016/J.It.2018.12.001 |
0.57 |
|
| 2019 |
Cubillos-Ruiz JR. Abstract TMIM-068: TARGETING ER STRESS RESPONSES TO UNLEASH THERAPEUTIC IMMUNITY AGAINST OVARIAN CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Tmim-068 |
0.615 |
|
| 2019 |
Kahn RM, Matrai C, Quinn AS, Talukdar N, McIntire P, Cubillos-Ruiz JR, Frey MK, Caputo TA, Holcomb KM, Chapman-Davis E. CD3+ and CD8+ tumor-infiltrating lymphocytes (TILs) as markers of improved prognosis in high-grade serous ovarian cancer Gynecologic Oncology. 154: 68. DOI: 10.1016/J.Ygyno.2019.04.162 |
0.531 |
|
| 2018 |
Song M, Sandoval TA, Chae CS, Chopra S, Tan C, Rutkowski MR, Raundhal M, Chaurio RA, Payne KK, Konrad C, Bettigole SE, Shin HR, Crowley MJP, Cerliani JP, Kossenkov AV, ... ... Cubillos-Ruiz JR, et al. IRE1α-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity. Nature. PMID 30305738 DOI: 10.1038/S41586-018-0597-X |
0.697 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Cubillos-Ruiz JR, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.325 |
|
| 2018 |
Cubillos-Ruiz JR. Abstract IA07: ER stress responses as new immune checkpoints in cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-Ia07 |
0.552 |
|
| 2018 |
Buskwofie A, Teran-Cabanillas E, Medina TS, Cubillos-Ruiz JR. Adoptive dendritic cell transfer following platinum-based chemotherapy extends overall host survival in a preclinical model of metastatic ovarian cancer Gynecologic Oncology. 149: 41-42. DOI: 10.1016/J.Ygyno.2018.04.091 |
0.404 |
|
| 2017 |
Márquez S, Fernández JJ, Terán-Cabanillas E, Herrero C, Alonso S, Azogil A, Montero O, Iwawaki T, Cubillos-Ruiz JR, Fernández N, Crespo MS. Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells. Frontiers in Immunology. 8: 639. PMID 28674530 DOI: 10.3389/Fimmu.2017.00639 |
0.363 |
|
| 2017 |
Chae CS, Teran-Cabanillas E, Cubillos-Ruiz JR. Dendritic cell rehab: new strategies to unleash therapeutic immunity in ovarian cancer. Cancer Immunology, Immunotherapy : Cii. PMID 28214928 DOI: 10.1007/S00262-017-1958-2 |
0.607 |
|
| 2017 |
Cubillos-Ruiz JR, Bettigole SE, Glimcher LH. Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer. Cell. 168: 692-706. PMID 28187289 DOI: 10.1016/J.Cell.2016.12.004 |
0.473 |
|
| 2017 |
Cubillos-Ruiz JR, Mohamed E, Rodriguez PC. Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer. Journal For Immunotherapy of Cancer. 5: 5. PMID 28105371 DOI: 10.1186/S40425-016-0203-4 |
0.585 |
|
| 2017 |
Crowley MJ, Yomtoubian S, Markowitz G, Altorki NK, Gao D, Cubillos-Ruiz J, Mittal V. Abstract 4498: Targeting IRE1a-XBP1 signaling in lung cancer Cancer Research. 77: 4498-4498. DOI: 10.1158/1538-7445.Am2017-4498 |
0.512 |
|
| 2016 |
Cubillos-Ruiz JR, Glimcher LH. Targeting abnormal ER stress responses in tumors: A new approach to cancer immunotherapy. Oncoimmunology. 5: e1098802. PMID 27141359 DOI: 10.1080/2162402X.2015.1098802 |
0.589 |
|
| 2016 |
Conejo-Garcia JR, Rutkowski MR, Cubillos-Ruiz JR. State-of-the-art of regulatory dendritic cells in cancer. Pharmacology & Therapeutics. PMID 27118338 DOI: 10.1016/J.Pharmthera.2016.04.003 |
0.728 |
|
| 2016 |
Cubillos-Ruiz JR, Bettigole SE, Glimcher LH. Molecular Pathways: Immunosuppressive Roles of IRE1α-XBP1 Signaling in Dendritic Cells of the Tumor Microenvironment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26979393 DOI: 10.1158/1078-0432.Ccr-15-1570 |
0.55 |
|
| 2015 |
Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161: 1527-38. PMID 26073941 DOI: 10.1016/J.Cell.2015.05.025 |
0.762 |
|
| 2013 |
Cubillos-Ruiz JR, Rutkowski MR, Tchou J, Conejo-Garcia JR. Reprogramming immune responses via microRNA modulation. Microrna Diagnostics and Therapeutics. 1. PMID 25285232 DOI: 10.2478/Micrnat-2013-0001 |
0.581 |
|
| 2013 |
Baird JR, Fox BA, Sanders KL, Lizotte PH, Cubillos-Ruiz JR, Scarlett UK, Rutkowski MR, Conejo-Garcia JR, Fiering S, Bzik DJ. Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Research. 73: 3842-51. PMID 23704211 DOI: 10.1158/0008-5472.Can-12-1974 |
0.794 |
|
| 2012 |
Cubillos-Ruiz JR, Sempere LF, Conejo-Garcia JR. Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles. Oncoimmunology. 1: 968-970. PMID 23162774 DOI: 10.4161/Onci.20020 |
0.686 |
|
| 2012 |
Rodriguez DA, Zamorano S, Lisbona F, Rojas-Rivera D, Urra H, Cubillos-Ruiz JR, Armisen R, Henriquez DR, Cheng EH, Letek M, Vaisar T, Irrazabal T, Gonzalez-Billault C, Letai A, Pimentel-Muiños FX, et al. BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α. The Embo Journal. 31: 2322-35. PMID 22510886 DOI: 10.1038/Emboj.2012.84 |
0.3 |
|
| 2012 |
Scarlett UK, Rutkowski MR, Rauwerdink AM, Fields J, Escovar-Fadul X, Baird J, Cubillos-Ruiz JR, Jacobs AC, Gonzalez JL, Weaver J, Fiering S, Conejo-Garcia JR. Ovarian cancer progression is controlled by phenotypic changes in dendritic cells. The Journal of Experimental Medicine. 209: 495-506. PMID 22351930 DOI: 10.1084/Jem.20111413 |
0.749 |
|
| 2012 |
Cubillos-Ruiz JR, Baird JR, Tesone AJ, Rutkowski MR, Scarlett UK, Camposeco-Jacobs AL, Anadon-Arnillas J, Harwood NM, Korc M, Fiering SN, Sempere LF, Conejo-Garcia JR. Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Research. 72: 1683-93. PMID 22307839 DOI: 10.1158/0008-5472.Can-11-3160 |
0.628 |
|
| 2011 |
Cubillos-Ruiz JR, Conejo-Garcia JR. It never rains but it pours: potential role of butyrophilins in inhibiting anti-tumor immune responses. Cell Cycle (Georgetown, Tex.). 10: 368-9. PMID 21270530 DOI: 10.4161/Cc.10.3.14565 |
0.776 |
|
| 2010 |
Cubillos-Ruiz JR, Martinez D, Scarlett UK, Rutkowski MR, Nesbeth YC, Camposeco-Jacobs AL, Conejo-Garcia JR. CD277 is a negative co-stimulatory molecule universally expressed by ovarian cancer microenvironmental cells. Oncotarget. 1: 329-38. PMID 21113407 DOI: 10.18632/Oncotarget.165 |
0.81 |
|
| 2010 |
Nesbeth YC, Martinez DG, Toraya S, Scarlett UK, Cubillos-Ruiz JR, Rutkowski MR, Conejo-Garcia JR. CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 5654-62. PMID 20400704 DOI: 10.4049/Jimmunol.0903247 |
0.826 |
|
| 2010 |
Cubillos-Ruiz JR, Rutkowski M, Conejo-Garcia JR. Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes. Cell Cycle (Georgetown, Tex.). 9: 260-8. PMID 20023378 DOI: 10.4161/Cc.9.2.10430 |
0.726 |
|
| 2009 |
Cubillos-Ruiz JR, Fiering S, Conejo-Garcia JR. Nanomolecular targeting of dendritic cells for ovarian cancer therapy. Future Oncology (London, England). 5: 1189-92. PMID 19852731 DOI: 10.2217/Fon.09.101 |
0.672 |
|
| 2009 |
Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, Martinez DG, Engle X, Gewirtz AT, Ahonen CL, Conejo-Garcia JR. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Research. 69: 7329-37. PMID 19738057 DOI: 10.1158/0008-5472.Can-09-0835 |
0.828 |
|
| 2009 |
Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/Jci37716 |
0.797 |
|
| 2009 |
Nesbeth Y, Scarlett U, Cubillos-Ruiz J, Martinez D, Engle X, Turk MJ, Conejo-Garcia JR. CCL5-mediated endogenous antitumor immunity elicited by adoptively transferred lymphocytes and dendritic cell depletion. Cancer Research. 69: 6331-8. PMID 19602595 DOI: 10.1158/0008-5472.Can-08-4329 |
0.82 |
|
| 2008 |
Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Buckanovich RJ, Benencia F, Stan RV, Keler T, Sarobe P, Sentman CL, Conejo-Garcia JR. Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity. Cancer Research. 68: 7684-91. PMID 18768667 DOI: 10.1158/0008-5472.Can-08-1167 |
0.803 |
|
| 2008 |
Huarte E, Cubillos-Ruiz JR, Nesbeth YC, Scarlett UK, Martinez DG, Engle XA, Rigby WF, Pioli PA, Guyre PM, Conejo-Garcia JR. PILAR is a novel modulator of human T-cell expansion. Blood. 112: 1259-68. PMID 18550855 DOI: 10.1182/Blood-2007-12-130773 |
0.785 |
|
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