Asrar B. Malik - Publications

Affiliations: 
1995 Physiology and Cell Biology Albany Medical College of Union University 
 1995- Pharmacology University of Illinois at Chicago, Chicago, IL, United States 
Website:
https://2018.cmos.org.tr/speaker/asrar-b-malik/

228 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mukhopadhyay A, Tsukasaki Y, Chan WC, Le JP, Kwok ML, Zhou J, Natarajan V, Mostafazadeh N, Maienschein-Cline M, Papautsky I, Tiruppathi C, Peng Z, Rehman J, Ganesh B, Komarova Y, ... Malik AB, et al. trans-Endothelial neutrophil migration activates bactericidal function via Piezo1 mechanosensing. Immunity. PMID 38091995 DOI: 10.1016/j.immuni.2023.11.007  0.335
2023 Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB. Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions. Nature Communications. 14: 6582. PMID 37852964 DOI: 10.1038/s41467-023-42225-2  0.343
2022 Waters SB, Dominguez JR, Cho HD, Sarich NA, Malik AB, Yamada KH. KIF13B-mediated VEGFR2 trafficking is essential for vascular leakage and metastasis in vivo. Life Science Alliance. 5. PMID 34670814 DOI: 10.26508/lsa.202101170  0.31
2021 Akhter MZ, Joshi JC, Balaji Ragunathrao VA, Maienschein-Cline M, Proia RL, Malik AB, Mehta D. Programming to S1PR1 Endothelial Cells Promote Restoration of Vascular Integrity. Circulation Research. PMID 33926208 DOI: 10.1161/CIRCRESAHA.120.318412  0.359
2020 Jones JH, Friedrich E, Hong Z, Minshall RD, Malik AB. Plasmalemmal Vesicle Associated Protein (PV1) in Caveolae Controls Lung Endothelial Permeability. American Journal of Respiratory Cell and Molecular Biology. PMID 32663411 DOI: 10.1165/rcmb.2020-0102OC  0.398
2020 Fu P, Ramchandran R, Shaaya M, Huang L, Ebenezer DL, Jiang Y, Komarova Y, Vogel SM, Malik AB, Minshall RD, Du G, Tonks NK, Natarajan V. Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation. The Journal of Biological Chemistry. PMID 32327488 DOI: 10.1074/Jbc.Ra119.011801  0.418
2020 Xiong S, Hong Z, Huang LS, Tsukasaki Y, Nepal S, Di A, Zhong M, Wu W, Ye Z, Gao X, Rao G, Mehta D, Rehman J, Malik AB. IL-1β Suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury. The Journal of Clinical Investigation. PMID 32298238 DOI: 10.1172/Jci136908  0.321
2020 Collins KB, Kang H, Matsche J, Klomp JE, Rehman J, Malik AB, Karginov AV. Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis. The Journal of Cell Biology. 219. PMID 31865373 DOI: 10.1083/Jcb.201903023  0.317
2019 Zhong M, Wu W, Kang H, Hong Z, Xiong S, Gao X, Rehman J, Komarova YA, Malik AB. Alveolar Stretch Activation of Endothelial Piezo1 Protects Adherens Junctions and Lung Vascular Barrier. American Journal of Respiratory Cell and Molecular Biology. PMID 31409093 DOI: 10.1165/Rcmb.2019-0024Oc  0.413
2019 Friedrich EE, Hong Z, Xiong S, Zhong M, Di A, Rehman J, Komarova YA, Malik AB. Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31186359 DOI: 10.1073/Pnas.1902165116  0.398
2019 Klomp JE, Shaaya M, Matsche J, Rebiai R, Aaron JS, Collins KB, Huyot V, Gonzalez AM, Muller WA, Chew TL, Malik AB, Karginov AV. Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response. Cell Chemical Biology. PMID 31130521 DOI: 10.1016/J.Chembiol.2019.04.007  0.346
2019 Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth PT, Benevolenskaya EV, Rehman J, Malik AB. Sox17 is required for endothelial regeneration following inflammation-induced vascular injury. Nature Communications. 10: 2126. PMID 31073164 DOI: 10.1038/S41467-019-10134-Y  0.341
2019 Juettner VV, Kruse K, Dan A, Vu VH, Khan Y, Le J, Leckband D, Komarova Y, Malik AB. VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism. The Journal of Cell Biology. PMID 30948425 DOI: 10.1083/Jcb.201807210  0.343
2018 Kruse K, Lee QS, Sun Y, Klomp J, Yang X, Huang F, Sun MY, Zhao S, Hong Z, Vogel SM, Shin JW, Leckband DE, Tai LM, Malik AB, Komarova YA. N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability. The Journal of Cell Biology. PMID 30463880 DOI: 10.1083/Jcb.201802076  0.359
2018 Kang H, Hong Z, Zhong M, Klomp J, Bayless KJ, Mehta D, Karginov AV, Hu G, Malik AB. Piezo1 mediates angiogenesis through activation of MT1-MMP signaling. American Journal of Physiology. Cell Physiology. PMID 30427721 DOI: 10.1152/Ajpcell.00346.2018  0.303
2018 Lv Y, Kim K, Sheng Y, Cho J, Qain Z, Zhao YY, Hu G, Pan D, Malik AB, Hu G. YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6. Circulation Research. PMID 29794022 DOI: 10.1161/Circresaha.118.313143  0.367
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Tiruppathi C, Malik AB, Rehman J. Response by Mittal et al to Letter Regarding Article, "Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury". Circulation Research. 121: e87. PMID 29217714 DOI: 10.1161/Circresaha.117.312146  0.351
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Rehman J, Tiruppathi C, Malik AB. Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury. Circulation Research. PMID 28790198 DOI: 10.1161/Circresaha.117.311747  0.31
2017 Soni D, Regmi SC, Wang DM, DebRoy A, Zhao YY, Vogel SM, Malik AB, Tiruppathi C. Pyk2 Phosphorylation of VE-PTP Downstream of STIM1 induced Ca2+ entry Regulates Disassembly of Adherens Junctions. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00008.2017. PMID 28385807 DOI: 10.1152/Ajplung.00008.2017  0.373
2017 Komarova YA, Kruse K, Mehta D, Malik AB. Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability. Circulation Research. 120: 179-206. PMID 28057793 DOI: 10.1161/CIRCRESAHA.116.306534  0.326
2016 Di A, Mehta D, Malik AB. ROS-activated calcium signaling mechanisms regulating endothelial barrier function. Cell Calcium. PMID 26905827 DOI: 10.1016/j.ceca.2016.02.002  0.335
2015 Yan Z, Wang ZG, Segev N, Hu S, Minshall RD, Dull RO, Zhang M, Malik AB, Hu G. Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier Function. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26663395 DOI: 10.1161/Atvbaha.115.306549  0.337
2015 Geyer M, Huang F, Sun Y, Vogel SM, Malik AB, Taylor CW, Komarova YA. Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells. Cell Reports. PMID 26119739 DOI: 10.1016/j.celrep.2015.06.001  0.302
2015 Gong H, Rehman J, Tang H, Wary K, Mittal M, Chaturvedi P, Zhao YY, Chatturvedi P, Zhao Y, Komarova YA, Komorova YA, Vogel SM, Malik AB. HIF2α signaling inhibits adherens junctional disruption in acute lung injury. The Journal of Clinical Investigation. 125: 652-64. PMID 25574837 DOI: 10.1172/Jci77701  0.4
2015 Daneshjou N, Sieracki N, van Nieuw Amerongen GP, Schwartz MA, Komarova YA, Malik AB, Conway DE. Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction. The Journal of Cell Biology. 208: 23-32. PMID 25559184 DOI: 10.1083/Jcb.201409108  0.309
2014 Yamada KH, Nakajima Y, Geyer M, Wary KK, Ushio-Fukai M, Komarova Y, Malik AB. KIF13B regulates angiogenesis through Golgi to plasma membrane trafficking of VEGFR2. Journal of Cell Science. 127: 4518-30. PMID 25128562 DOI: 10.1242/jcs.156109  0.312
2014 Hecquet CM, Zhang M, Mittal M, Vogel SM, Di A, Gao X, Bonini MG, Malik AB. Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis. Circulation Research. 114: 469-79. PMID 24337049 DOI: 10.1161/Circresaha.114.302414  0.306
2014 Marsboom G, Theriault K, Debroy A, Mao M, Baig S, Tiruppathi C, Bonini M, Rehman J, Austin E, Malik A. Newly identified caveolin-1 mutation associated with heritable human pulmonary arterial hypertension mediates hyperproliferation via augmented calcium signaling (1089.10) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1089.10  0.333
2013 Jiao H, Zhang Y, Yan Z, Wang ZG, Liu G, Minshall RD, Malik AB, Hu G. Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 191: 6191-9. PMID 24244013 DOI: 10.4049/jimmunol.1300873  0.31
2013 Han J, Zhang G, Welch EJ, Liang Y, Fu J, Vogel SM, Lowell CA, Du X, Cheresh DA, Malik AB, Li Z. A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood. 122: 4140-9. PMID 24108461 DOI: 10.1182/Blood-2013-03-491423  0.338
2012 Vogel SM, Malik AB. Cytoskeletal dynamics and lung fluid balance. Comprehensive Physiology. 2: 449-78. PMID 23728978 DOI: 10.1002/cphy.c100006  0.39
2012 Komarova YA, Huang F, Geyer M, Daneshjou N, Garcia A, Idalino L, Kreutz B, Mehta D, Malik AB. VE-cadherin signaling induces EB3 phosphorylation to suppress microtubule growth and assemble adherens junctions. Molecular Cell. 48: 914-25. PMID 23159740 DOI: 10.1016/J.Molcel.2012.10.011  0.341
2012 Tauseef M, Knezevic N, Chava KR, Smith M, Sukriti S, Gianaris N, Obukhov AG, Vogel SM, Schraufnagel DE, Dietrich A, Birnbaumer L, Malik AB, Mehta D. TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. The Journal of Experimental Medicine. 209: 1953-68. PMID 23045603 DOI: 10.1085/Jgp1405Oia9  0.369
2012 Naikawadi RP, Cheng N, Vogel SM, Qian F, Wu D, Malik AB, Ye RD. A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability. Circulation Research. 111: 1517-27. PMID 22965143 DOI: 10.1161/Circresaha.112.273078  0.343
2012 Liu G, Place AT, Chen Z, Brovkovych VM, Vogel SM, Muller WA, Skidgel RA, Malik AB, Minshall RD. ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration. Blood. 120: 1942-52. PMID 22806890 DOI: 10.1182/Blood-2011-12-397430  0.377
2012 Chen Z, Bakhshi FR, Shajahan AN, Sharma T, Mao M, Trane A, Bernatchez P, van Nieuw Amerongen GP, Bonini MG, Skidgel RA, Malik AB, Minshall RD. Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition. Molecular Biology of the Cell. 23: 1388-98. PMID 22323292 DOI: 10.1091/Mbc.E11-09-0811  0.348
2011 Siddiqui MR, Komarova YA, Vogel SM, Gao X, Bonini MG, Rajasingh J, Zhao YY, Brovkovych V, Malik AB. Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability. The Journal of Cell Biology. 193: 841-50. PMID 21624953 DOI: 10.1083/Jcb.201012129  0.372
2011 Liu G, Vogel SM, Gao X, Javaid K, Hu G, Danilov SM, Malik AB, Minshall RD. Src phosphorylation of endothelial cell surface intercellular adhesion molecule-1 mediates neutrophil adhesion and contributes to the mechanism of lung inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1342-50. PMID 21474822 DOI: 10.1161/ATVBAHA.110.222208  0.312
2011 McLaughlin J, Ramachandran R, Kaynar A, Shapiro S, Angus D, Malik A. Regulation of endothelial function by coagulation proteases in sepsis Critical Care. 15: 251. DOI: 10.1186/Cc9671  0.431
2011 Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Cα phosphorylates the TRPC1 channel and regulates store-operated Ca2+entry in endothelial cells. Journal of Biological Chemistry. 286: 36162-36162. DOI: 10.1074/Jbc.A111.313975  0.58
2010 Cowan CE, Kohler EE, Dugan TA, Mirza MK, Malik AB, Wary KK. Kruppel-like factor-4 transcriptionally regulates VE-cadherin expression and endothelial barrier function. Circulation Research. 107: 959-66. PMID 20724706 DOI: 10.1161/CIRCRESAHA.110.219592  0.305
2010 Mirza MK, Sun Y, Zhao YD, Potula HH, Frey RS, Vogel SM, Malik AB, Zhao YY. FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression. The Journal of Experimental Medicine. 207: 1675-85. PMID 20660612 DOI: 10.1084/jem.20091857  0.329
2010 Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvascular Research. 80: 240-9. PMID 20417648 DOI: 10.1016/J.Mvr.2010.04.007  0.659
2010 Mirza MK, Yuan J, Gao XP, Garrean S, Brovkovych V, Malik AB, Tiruppathi C, Zhao YY. Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation. The American Journal of Pathology. 176: 2344-51. PMID 20304961 DOI: 10.2353/Ajpath.2010.091088  0.321
2010 Hecquet CM, Ahmmed GU, Malik AB. TRPM2 channel regulates endothelial barrier function. Advances in Experimental Medicine and Biology. 661: 155-67. PMID 20204729 DOI: 10.1007/978-1-60761-500-2_10  0.35
2010 Zhao YD, Ohkawara H, Vogel SM, Malik AB, Zhao YY. Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L36-44. PMID 19880506 DOI: 10.1152/ajplung.00064.2009  0.403
2009 Zhao YY, Malik AB. A novel insight into the mechanism of pulmonary hypertension involving caveolin-1 deficiency and endothelial nitric oxide synthase activation. Trends in Cardiovascular Medicine. 19: 238-42. PMID 20382348 DOI: 10.1016/j.tcm.2010.02.003  0.361
2009 Gorovoy M, Han J, Pan H, Welch E, Neamu R, Jia Z, Predescu D, Vogel S, Minshall RD, Ye RD, Malik AB, Voyno-Yasenetskaya T. LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs. Circulation Research. 105: 549-56. PMID 19679840 DOI: 10.1161/Circresaha.109.195883  0.34
2009 Klein IK, Predescu DN, Sharma T, Knezevic I, Malik AB, Predescu S. Intersectin-2L regulates caveola endocytosis secondary to Cdc42-mediated actin polymerization. The Journal of Biological Chemistry. 284: 25953-61. PMID 19622753 DOI: 10.1074/Jbc.M109.035071  0.75
2009 Knezevic II, Predescu SA, Neamu RF, Gorovoy MS, Knezevic NM, Easington C, Malik AB, Predescu DN. Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability. The Journal of Biological Chemistry. 284: 5381-94. PMID 19095647 DOI: 10.1074/jbc.M808958200  0.398
2009 Bair AM, Thippegowda PB, Freichel M, Cheng N, Ye RD, Vogel SM, Yu Y, Flockerzi V, Malik AB, Tiruppathi C. Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta. The Journal of Biological Chemistry. 284: 563-74. PMID 18990707 DOI: 10.1074/Jbc.M803984200  0.307
2008 Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D. Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circulation Research. 103: 1164-72. PMID 18849324 DOI: 10.1161/01.RES.0000338501.84810.51  0.403
2008 Ramchandran R, Mehta D, Vogel SM, Mirza MK, Kouklis P, Malik AB. Critical role of Cdc42 in mediating endothelial barrier protection in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L363-9. PMID 18515405 DOI: 10.1152/ajplung.90241.2008  0.404
2008 Hu G, Vogel SM, Schwartz DE, Malik AB, Minshall RD. Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circulation Research. 102: e120-31. PMID 18511851 DOI: 10.1161/CIRCRESAHA.107.167486  0.461
2008 Vandenbroucke E, Mehta D, Minshall R, Malik AB. Regulation of endothelial junctional permeability. Annals of the New York Academy of Sciences. 1123: 134-45. PMID 18375586 DOI: 10.1196/annals.1420.016  0.371
2008 Maniatis NA, Shinin V, Schraufnagel DE, Okada S, Vogel SM, Malik AB, Minshall RD. Increased pulmonary vascular resistance and defective pulmonary artery filling in caveolin-1-/- mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L865-73. PMID 18192592 DOI: 10.1152/ajplung.00079.2007  0.302
2008 Hecquet CM, Ahmmed GU, Vogel SM, Malik AB. Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. Circulation Research. 102: 347-55. PMID 18048770 DOI: 10.1161/Circresaha.107.160176  0.301
2008 Hu G, Ye RD, Dinauer MC, Malik AB, Minshall RD. Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L178-86. PMID 17993589 DOI: 10.1152/Ajplung.00263.2007  0.375
2008 Zhao Y, Ohkawara H, Malik A. Bone Marrow‐Derived Endothelial Progenitor Cells Strengthen the Endothelial Barrier by a Rac1/Cdc42‐Mediated Adherens Junction Assembly The Faseb Journal. 22: 660-660. DOI: 10.1096/Fasebj.22.2_Supplement.660  0.365
2007 Komarova YA, Mehta D, Malik AB. Dual regulation of endothelial junctional permeability. Science's Stke : Signal Transduction Knowledge Environment. 2007: re8. PMID 18000237 DOI: 10.1126/stke.4122007re8  0.305
2007 Predescu SA, Predescu DN, Malik AB. Molecular determinants of endothelial transcytosis and their role in endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L823-42. PMID 17644753 DOI: 10.1152/AJPLUNG.00436.2006  0.302
2007 Knezevic N, Roy A, Timblin B, Konstantoulaki M, Sharma T, Malik AB, Mehta D. GDI-1 phosphorylation switch at serine 96 induces RhoA activation and increased endothelial permeability. Molecular and Cellular Biology. 27: 6323-33. PMID 17636025 DOI: 10.1128/Mcb.00523-07  0.796
2007 Broman MT, Mehta D, Malik AB. Cdc42 regulates the restoration of endothelial adherens junctions and permeability. Trends in Cardiovascular Medicine. 17: 151-6. PMID 17574122 DOI: 10.1016/j.tcm.2007.03.004  0.351
2007 Gorovoy M, Neamu R, Niu J, Vogel S, Predescu D, Miyoshi J, Takai Y, Kini V, Mehta D, Malik AB, Voyno-Yasenetskaya T. RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circulation Research. 101: 50-8. PMID 17525371 DOI: 10.1161/Circresaha.106.145847  0.399
2007 Predescu SA, Predescu DN, Knezevic I, Klein IK, Malik AB. Intersectin-1s regulates the mitochondrial apoptotic pathway in endothelial cells. The Journal of Biological Chemistry. 282: 17166-78. PMID 17405881 DOI: 10.1074/Jbc.M608996200  0.746
2007 McLaughlin JN, Patterson MM, Malik AB. Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. Proceedings of the National Academy of Sciences of the United States of America. 104: 5662-7. PMID 17376866 DOI: 10.1073/Pnas.0700763104  0.306
2007 Siddiqui SS, Siddiqui ZK, Uddin S, Minshall RD, Malik AB. p38 MAPK activation coupled to endocytosis is a determinant of endothelial monolayer integrity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L114-24. PMID 16891390 DOI: 10.1152/Ajplung.00257.2005  0.353
2006 Singh I, Knezevic N, Ahmmed GU, Kini V, Malik AB, Mehta D. Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin. The Journal of Biological Chemistry. 282: 7833-43. PMID 17197445 DOI: 10.1074/jbc.M608288200  0.356
2006 Tiruppathi C, Ahmmed GU, Vogel SM, Malik AB. Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (New York, N.Y. : 1994). 13: 693-708. PMID 17085428 DOI: 10.1080/10739680600930347  0.35
2006 Maniatis NA, Brovkovych V, Allen SE, John TA, Shajahan AN, Tiruppathi C, Vogel SM, Skidgel RA, Malik AB, Minshall RD. Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circulation Research. 99: 870-7. PMID 16973909 DOI: 10.1161/01.Res.0000245187.08026.47  0.373
2006 Zhao YY, Gao XP, Zhao YD, Mirza MK, Frey RS, Kalinichenko VV, Wang IC, Costa RH, Malik AB. Endothelial cell-restricted disruption of FoxM1 impairs endothelial repair following LPS-induced vascular injury. The Journal of Clinical Investigation. 116: 2333-43. PMID 16955137 DOI: 10.1172/JCI27154  0.361
2006 Orrington-Myers J, Gao X, Kouklis P, Broman M, Rahman A, Vogel SM, Malik AB. Regulation of lung neutrophil recruitment by VE-cadherin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L764-71. PMID 16782751 DOI: 10.1152/ajplung.00502.2005  0.339
2006 Vogel SM, Orrington-Myers J, Broman M, Malik AB. De novo ICAM-1 synthesis in the mouse lung: model of assessment of protein expression in lungs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L496-501. PMID 16714332 DOI: 10.1152/ajplung.00353.2005  0.302
2006 Paria BC, Bair AM, Xue J, Yu Y, Malik AB, Tiruppathi C. Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells. The Journal of Biological Chemistry. 281: 20715-27. PMID 16709572 DOI: 10.1074/Jbc.M600722200  0.305
2006 Frey RS, Gao X, Javaid K, Siddiqui SS, Rahman A, Malik AB. Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. The Journal of Biological Chemistry. 281: 16128-38. PMID 16527821 DOI: 10.1074/Jbc.M508810200  0.309
2006 Holinstat M, Knezevic N, Broman M, Samarel AM, Malik AB, Mehta D. Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. The Journal of Biological Chemistry. 281: 2296-305. PMID 16308318 DOI: 10.1074/Jbc.M511248200  0.679
2005 Broman MT, Kouklis P, Gao X, Ramchandran R, Neamu RF, Minshall RD, Malik AB. Cdc42 regulates adherens junction stability and endothelial permeability by inducing alpha-catenin interaction with the vascular endothelial cadherin complex. Circulation Research. 98: 73-80. PMID 16322481 DOI: 10.1161/01.RES.0000198387.44395.e9  0.353
2005 Miyawaki-Shimizu K, Predescu D, Shimizu J, Broman M, Predescu S, Malik AB. siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L405-13. PMID 16183667 DOI: 10.1152/ajplung.00292.2005  0.387
2005 Predescu SA, Predescu DN, Shimizu K, Klein IK, Malik AB. Cholesterol-dependent syntaxin-4 and SNAP-23 clustering regulates caveolar fusion with the endothelial plasma membrane. The Journal of Biological Chemistry. 280: 37130-8. PMID 16118213 DOI: 10.1074/Jbc.M505659200  0.738
2005 Predescu D, Predescu S, Shimizu J, Miyawaki-Shimizu K, Malik AB. Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L371-81. PMID 16093363 DOI: 10.1152/ajplung.00175.2004  0.318
2005 Jho D, Mehta D, Ahmmed G, Gao XP, Tiruppathi C, Broman M, Malik AB. Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circulation Research. 96: 1282-90. PMID 15920022 DOI: 10.1161/01.Res.0000171894.03801.03  0.742
2005 Gao XP, Liu Q, Broman M, Predescu D, Frey RS, Malik AB. Inactivation of CD11b in a mouse transgenic model protects against sepsis-induced lung PMN infiltration and vascular injury. Physiological Genomics. 21: 230-42. PMID 15831844 DOI: 10.1152/physiolgenomics.00291.2004  0.313
2005 Lin P, Welch EJ, Gao XP, Malik AB, Ye RD. Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP. Journal of Immunology (Baltimore, Md. : 1950). 174: 2981-9. PMID 15728511 DOI: 10.4049/Jimmunol.174.5.2981  0.332
2005 Mehta D, Konstantoulaki M, Ahmmed GU, Malik AB. Sphingosine 1-phosphate-induced mobilization of intracellular Ca2+ mediates rac activation and adherens junction assembly in endothelial cells. The Journal of Biological Chemistry. 280: 17320-8. PMID 15728185 DOI: 10.1074/Jbc.M411674200  0.773
2005 Fu J, Naren AP, Gao X, Ahmmed GU, Malik AB. Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. The Journal of Biological Chemistry. 280: 3178-84. PMID 15576373 DOI: 10.1074/Jbc.M410044200  0.372
2005 Mehta D, Bhattacharya J, Matthay MA, Malik AB. Integrated control of lung fluid balance. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L1081-90. PMID 15531757 DOI: 10.1152/ajplung.00268.2004  0.363
2004 Paria BC, Vogel SM, Ahmmed GU, Alamgir S, Shroff J, Malik AB, Tiruppathi C. Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L1303-13. PMID 15347566 DOI: 10.1152/Ajplung.00240.2004  0.305
2004 Shajahan AN, Tiruppathi C, Smrcka AV, Malik AB, Minshall RD. Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. The Journal of Biological Chemistry. 279: 48055-62. PMID 15345719 DOI: 10.1074/Jbc.M405837200  0.322
2004 Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. The Journal of Biological Chemistry. 279: 20941-9. PMID 15016832 DOI: 10.1074/Jbc.M313975200  0.603
2004 Kouklis P, Konstantoulaki M, Vogel S, Broman M, Malik AB. Cdc42 regulates the restoration of endothelial barrier function. Circulation Research. 94: 159-66. PMID 14656933 DOI: 10.1161/01.Res.0000110418.38500.31  0.803
2003 Minshall RD, Sessa WC, Stan RV, Anderson RG, Malik AB. Caveolin regulation of endothelial function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1179-83. PMID 14604847 DOI: 10.1152/Ajplung.00242.2003  0.351
2003 Ong ES, Gao XP, Xu N, Predescu D, Rahman A, Broman MT, Jho DH, Malik AB. E. coli pneumonia induces CD18-independent airway neutrophil migration in the absence of increased lung vascular permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L879-88. PMID 12818890 DOI: 10.1152/Ajplung.00134.2003  0.719
2003 Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB. RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. The Journal of Biological Chemistry. 278: 33492-500. PMID 12766172 DOI: 10.1074/Jbc.M302401200  0.627
2003 Holinstat M, Mehta D, Kozasa T, Minshall RD, Malik AB. Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement. The Journal of Biological Chemistry. 278: 28793-8. PMID 12754211 DOI: 10.1074/Jbc.M303900200  0.622
2003 Konstantoulaki M, Kouklis P, Malik AB. Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L434-42. PMID 12740216 DOI: 10.1152/Ajplung.00075.2003  0.785
2003 Javaid K, Rahman A, Anwar KN, Frey RS, Minshall RD, Malik AB. Tumor necrosis factor-alpha induces early-onset endothelial adhesivity by protein kinase Czeta-dependent activation of intercellular adhesion molecule-1. Circulation Research. 92: 1089-97. PMID 12714560 DOI: 10.1161/01.RES.0000072971.88704.CB  0.307
2003 Kouklis P, Konstantoulaki M, Malik AB. VE-cadherin-induced Cdc42 signaling regulates formation of membrane protrusions in endothelial cells. The Journal of Biological Chemistry. 278: 16230-6. PMID 12595527 DOI: 10.1074/Jbc.M212591200  0.774
2002 Tiruppathi C, Minshall RD, Paria BC, Vogel SM, Malik AB. Role of Ca2+ signaling in the regulation of endothelial permeability. Vascular Pharmacology. 39: 173-85. PMID 12747958 DOI: 10.1016/S1537-1891(03)00007-7  0.327
2002 Skidgel RA, Gao XP, Brovkovych V, Rahman A, Jho D, Predescu S, Standiford TJ, Malik AB. Nitric oxide stimulates macrophage inflammatory protein-2 expression in sepsis. Journal of Immunology (Baltimore, Md. : 1950). 169: 2093-101. PMID 12165537 DOI: 10.4049/Jimmunol.169.4.2093  0.72
2002 Tiruppathi C, Freichel M, Vogel SM, Paria BC, Mehta D, Flockerzi V, Malik AB. Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circulation Research. 91: 70-6. PMID 12114324 DOI: 10.1161/01.Res.0000023391.40106.A8  0.307
2002 Vanhauwe JF, Thomas TO, Minshall RD, Tiruppathi C, Li A, Gilchrist A, Yoon EJ, Malik AB, Hamm HE. Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes. The Journal of Biological Chemistry. 277: 34143-9. PMID 12039967 DOI: 10.1074/Jbc.M204477200  0.485
2002 Frey RS, Rahman A, Kefer JC, Minshall RD, Malik AB. PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circulation Research. 90: 1012-9. PMID 12016268 DOI: 10.1161/01.RES.0000017631.28815.8E  0.304
2002 Minshall RD, Tiruppathi C, Vogel SM, Malik AB. Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochemistry and Cell Biology. 117: 105-12. PMID 11935286 DOI: 10.1007/S00418-001-0367-X  0.324
2002 Mehta D, Tiruppathi C, Sandoval R, Minshall RD, Holinstat M, Malik AB. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. The Journal of Physiology. 539: 779-89. PMID 11897849 DOI: 10.1113/Jphysiol.2001.013289  0.671
2002 Xu N, Gao XP, Minshall RD, Rahman A, Malik AB. Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L796-802. PMID 11880306 DOI: 10.1152/ajplung.00298.2001  0.306
2001 Sandoval R, Malik AB, Minshall RD, Kouklis P, Ellis CA, Tiruppathi C. Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions. The Journal of Physiology. 533: 433-45. PMID 11389203 DOI: 10.1111/J.1469-7793.2001.0433A.X  0.318
2001 Mehta D, Rahman A, Malik AB. Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function. The Journal of Biological Chemistry. 276: 22614-20. PMID 11309397 DOI: 10.1074/jbc.M101927200  0.318
2001 Sandoval R, Malik AB, Naqvi T, Mehta D, Tiruppathi C. Requirement for Ca2+ signaling in the mechanism of thrombin-induced increase in endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L239-47. PMID 11159002 DOI: 10.1152/Ajplung.2001.280.2.L239  0.335
2000 Gao X, Kouklis P, Xu N, Minshall RD, Sandoval R, Vogel SM, Malik AB. Reversibility of increased microvessel permeability in response to VE-cadherin disassembly. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L1218-25. PMID 11076812 DOI: 10.1152/Ajplung.2000.279.6.L1218  0.313
2000 Minshall RD, Tiruppathi C, Vogel SM, Niles WD, Gilchrist A, Hamm HE, Malik AB. Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway. The Journal of Cell Biology. 150: 1057-70. PMID 10973995 DOI: 10.1083/Jcb.150.5.1057  0.512
2000 Xu N, Rahman A, Minshall RD, Tiruppathi C, Malik AB. beta(2)-Integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice. Circulation Research. 87: 254-60. PMID 10926878 DOI: 10.1161/01.Res.87.3.254  0.389
2000 Tiruppathi C, Yan W, Sandoval R, Naqvi T, Pronin AN, Benovic JL, Malik AB. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7440-5. PMID 10861009 DOI: 10.1073/Pnas.97.13.7440  0.378
1999 Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 274: 13718-27. PMID 10224146 DOI: 10.1074/Jbc.274.19.13718  0.552
1998 Zhou MY, Lo SK, Bergenfeldt M, Tiruppathi C, Jaffe A, Xu N, Malik AB. In vivo expression of neutrophil inhibitory factor via gene transfer prevents lipopolysaccharide-induced lung neutrophil infiltration and injury by a beta2 integrin-dependent mechanism. The Journal of Clinical Investigation. 101: 2427-37. PMID 9616214 DOI: 10.1172/Jci407  0.368
1997 Aschner JL, Lum H, Fletcher PW, Malik AB. Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation. Journal of Cellular Physiology. 173: 387-96. PMID 9369952 DOI: 10.1002/(Sici)1097-4652(199712)173:3<387::Aid-Jcp11>3.0.Co;2-9  0.352
1997 Ohno S, Malik AB. Polymorphonuclear leucocyte (PMN) inhibitory factor prevents PMN-dependent endothelial cell injury by an anti-adhesive mechanism. Journal of Cellular Physiology. 171: 212-6. PMID 9130469 DOI: 10.1002/(SICI)1097-4652(199705)171:2<212::AID-JCP12>3.0.CO;2-F  0.33
1997 Lum H, Malik AB. Mechanisms of increased endothelial permeability. Canadian Journal of Physiology and Pharmacology. 74: 787-800. PMID 8946065 DOI: 10.1139/Y96-081  0.329
1994 Lum H, Andersen TT, Fenton JW, Malik AB. Thrombin receptor activation peptide induces pulmonary vasoconstriction American Journal of Physiology - Cell Physiology. 266. PMID 8141259 DOI: 10.1152/Ajpcell.1994.266.2.C448  0.309
1994 Lum H, Malik AB. Regulation of vascular endothelial barrier function. The American Journal of Physiology. 267: L223-41. PMID 7943249 DOI: 10.1152/Ajplung.1994.267.3.L223  0.33
1994 Lum H, Gibbs L, Lai L, Malik AB. CD18 integrin-dependent endothelial injury: effects of opsonized zymosan and phorbol ester activation. Journal of Leukocyte Biology. 55: 58-63. PMID 7904295 DOI: 10.1002/Jlb.55.1.58  0.314
1994 Lo SK, Bevilacqua B, Malik AB. E-selectin ligands mediate tumor necrosis factor-induced neutrophil sequestration and pulmonary edema in guinea pig lungs. Circulation Research. 75: 955-60. PMID 7525105 DOI: 10.1161/01.RES.75.6.955  0.303
1993 Siflinger-Birnboim A, Malik AB. Neutrophil adhesion to endothelial cells impairs the effects of catalase and glutathione in preventing endothelial injury. Journal of Cellular Physiology. 155: 234-9. PMID 8482715 DOI: 10.1002/jcp.1041550203  0.317
1993 Lum H, Andersen TT, Siflinger-Birnboim A, Tiruppathi C, Goligorsky MS, Fenton JW, Malik AB. Thrombin receptor peptide inhibits thrombin-induced increase in endothelial permeability by receptor desensitization. The Journal of Cell Biology. 120: 1491-9. PMID 8383691 DOI: 10.1083/Jcb.120.6.1491  0.312
1993 Siflinger-Birnboim A, Bode DC, Malik AB. Adenosine 3',5'-cyclic monophosphate attenuates neutrophil-mediated increase in endothelial permeability. The American Journal of Physiology. 264: H370-5. PMID 8383454 DOI: 10.1152/ajpheart.1993.264.2.H370  0.327
1993 Kaslovsky RA, Lai L, Parker K, Malik AB. Mediation of endothelial injury following neutrophil adherence to extracellular matrix. The American Journal of Physiology. 264: L401-5. PMID 8097378 DOI: 10.1152/ajplung.1993.264.4.L401  0.322
1993 Del Vecchio PJ, Siflinger-Birnboim A, Belloni PN, Holleran LA, Lum H, Malik AB. Culture and characterization of pulmonary microvascular endothelial cells. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 711-5. PMID 1483962 DOI: 10.1007/BF02631058  0.301
1992 Lo SK, Del Vecchio PJ, Lum H, Malik AB. Fibrin contact increases endothelial permeability to albumin. Journal of Cellular Physiology. 151: 63-70. PMID 1560049 DOI: 10.1002/jcp.1041510111  0.347
1992 Paty PS, Sherman PF, Shepard JM, Malik AB, Kaplan JE. Role of adenosine in platelet-mediated reduction in pulmonary vascular permeability. The American Journal of Physiology. 262: H771-7. PMID 1558187 DOI: 10.1152/ajpheart.1992.262.3.H771  0.305
1992 Tiruppathi C, Malik AB, Del Vecchio PJ, Keese CR, Giaever I. Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. 89: 7919-23. PMID 1518814 DOI: 10.1073/Pnas.89.17.7919  0.35
1992 Sugama Y, Malik AB. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circulation Research. 71: 1015-9. PMID 1381292 DOI: 10.1161/01.RES.71.4.1015  0.325
1992 Lo SK, Everitt J, Gu J, Malik AB. Tumor necrosis factor mediates experimental pulmonary edema by ICAM-1 and CD18-dependent mechanisms. The Journal of Clinical Investigation. 89: 981-8. PMID 1347298 DOI: 10.1172/JCI115681  0.34
1991 Horgan MJ, Pinheiro JM, Malik AB. Mechanism of endothelin-1-induced pulmonary vasoconstriction. Circulation Research. 69: 157-64. PMID 2054931 DOI: 10.1161/01.RES.69.1.157  0.313
1991 Horgan MJ, Ge M, Gu J, Rothlein R, Malik AB. Role of ICAM-1 in neutrophil-mediated lung vascular injury after occlusion and reperfusion. The American Journal of Physiology. 261: H1578-84. PMID 1683173 DOI: 10.1152/ajpheart.1991.261.5.H1578  0.324
1991 Fisher MA, Del Vecchio PJ, Palace GP, Denholm EM, Lai L, Malik AB. Thrombin-mediated release of lipids from pulmonary artery endothelial cells promotes neutrophil adherence. Circulation Research. 68: 930-9. PMID 1672631 DOI: 10.1161/01.RES.68.4.930  0.364
1990 Lo SK, Garcia-Szabo RR, Malik AB. Leukocyte repletion reverses protective effect of neutropenia in thrombin-induced increase in lung vascular permeability. The American Journal of Physiology. 259: H149-55. PMID 2375401 DOI: 10.1152/ajpheart.1990.259.1.H149  0.408
1990 Lynch JJ, Ferro TJ, Blumenstock FA, Brockenauer AM, Malik AB. Increased endothelial albumin permeability mediated by protein kinase C activation. The Journal of Clinical Investigation. 85: 1991-8. PMID 2347922 DOI: 10.1172/JCI114663  0.383
1990 Malik AB. Pulmonary microembolism and lung vascular injury The European Respiratory Journal. Supplement. 11. PMID 2278611  0.381
1990 Burgess CA, McCandless BK, Cooper JA, Malik AB. Leukotriene B4 increases pulmonary transvascular filtration by a neutrophil-independent mechanism. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1260-4. PMID 2160448 DOI: 10.1152/jappl.1990.68.3.1260  0.381
1990 Gibbs LS, Lai L, Malik AB. Tumor necrosis factor enhances the neutrophil-dependent increase in endothelial permeability Journal of Cellular Physiology. 145: 496-500. PMID 1980275 DOI: 10.1002/jcp.1041450315  0.377
1990 Horgan MJ, Wright SD, Malik AB. Antibody against leukocyte integrin (CD18) prevents reperfusion-induced lung vascular injury American Journal of Physiology - Lung Cellular and Molecular Physiology. 259. PMID 1977323 DOI: 10.1152/ajplung.1990.259.4.l315  0.316
1990 Lum H, Barr DA, Shaffer JR, Gordon RJ, Ezrin AM, Malik AB. Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms Circulation Research. 70: 991-998. PMID 1568306 DOI: 10.1161/01.RES.70.5.991  0.349
1990 Malik AB. Mechanisms of lung vascular injury and edema induced by pulmonary microembolism Medical Principles and Practice. 2: 1-9. DOI: 10.1159/000157326  0.416
1989 Siflinger-Birnboim A, Cooper JA, del Vecchio PJ, Lum H, Malik AB. Selectivity of the endothelial monolayer: effects of increased permeability. Microvascular Research. 36: 216-27. PMID 3231121 DOI: 10.1016/0026-2862(88)90023-4  0.344
1989 Horgan MJ, Lum H, Malik AB. Pulmonary edema after pulmonary artery occlusion and reperfusion. The American Review of Respiratory Disease. 140: 1421-8. PMID 2817606 DOI: 10.1164/ajrccm/140.5.1421  0.318
1989 Garcia-Szabo RR, Fenton JW, Lo SK, Hussain M, Malik AB. Increased transvascular protein transport in lungs induced by nonthrombogenic gamma-thrombin. The American Journal of Physiology. 256: H1690-6. PMID 2735438 DOI: 10.1152/ajpheart.1989.256.6.H1690  0.31
1989 Ferro TJ, Lynch JJ, Malik AB. Macrophages activated by fibrin increase albumin permeability across pulmonary artery endothelial monolayers. The American Review of Respiratory Disease. 139: 940-5. PMID 2539036 DOI: 10.1164/ajrccm/139.4.940  0.382
1989 Perlman MB, Johnson A, Jubiz W, Malik AB. Lipoxygenase products induce neutrophil activation and increase endothelial permeability after thrombin-induced pulmonary microembolism. Circulation Research. 64: 62-73. PMID 2491795 DOI: 10.1161/01.RES.64.1.62  0.661
1989 Ferro TJ, Malik AB. Mechanisms of lung vascular injury and edema after pulmonary microembolism Journal of Critical Care. 4: 118-126. DOI: 10.1016/0883-9441(89)90127-5  0.313
1988 Horgan MJ, Fenton JW, Malik AB. Alpha-thrombin-induced pulmonary vasoconstriction. Journal of Applied Physiology (Bethesda, Md. : 1985). 63: 1993-2000. PMID 3693233 DOI: 10.1152/jappl.1987.63.5.1993  0.339
1988 Garcia-Szabo R, Johnson A, Malik AB. Thromboxane increases pulmonary vascular resistance and transvascular fluid and protein exchange after pulmonary microembolism. Prostaglandins. 35: 707-21. PMID 3399679 DOI: 10.1016/0090-6980(88)90144-X  0.622
1988 Lo SK, Burhop KE, Kaplan JE, Malik AB. Role of platelets in maintenance of pulmonary vascular permeability to protein. The American Journal of Physiology. 254: H763-71. PMID 3354701 DOI: 10.1152/ajpheart.1988.254.4.H763  0.355
1988 Burhop KE, Selig WM, Malik AB. Monohydroxyeicosatetraenoic acids (5-HETE and 15-HETE) induce pulmonary vasoconstriction and edema. Circulation Research. 62: 687-98. PMID 3349572 DOI: 10.1161/01.RES.62.4.687  0.346
1988 Kaplan JE, Malik AB. Thrombin-induced intravascular coagulation: role in vascular injury. Seminars in Thrombosis and Hemostasis. 13: 398-415. PMID 3321435 DOI: 10.1055/S-2007-1003517  0.364
1988 Bizios R, Lai LC, Cooper JA, Del Vecchio PJ, Malik AB. Thrombin-induced adherence of neutrophils to cultured endothelial monolayers: Increased endothelial adhesiveness Journal of Cellular Physiology. 134: 275-280. PMID 3279059 DOI: 10.1002/Jcp.1041340214  0.326
1988 Cooper JA, Lo SK, Malik AB. Fibrin is a determinant of neutrophil sequestration in the lung. Circulation Research. 63: 735-41. PMID 3168176 DOI: 10.1161/01.RES.63.4.735  0.318
1988 Horvath CJ, Ferro TJ, Jesmok G, Malik AB. Recombinant tumor necrosis factor increases pulmonary vascular permeability independent of neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 85: 9219-23. PMID 3143114 DOI: 10.1073/pnas.85.23.9219  0.361
1988 Noonan TC, Selig WM, Burhop KE, Burgess CA, Malik AB. Pulmonary microvascular response to LTB4: Effects of perfusate composition Journal of Applied Physiology. 64: 1989-1996. PMID 2839452 DOI: 10.1152/jappl.1988.64.5.1989  0.351
1988 Garcia JG, Perlman MB, Ferro TJ, Johnson A, Jubiz W, Malik AB. Inflammatory events after fibrin microembolization. Alterations in alveolar macrophage and neutrophil function. The American Review of Respiratory Disease. 137: 630-5. PMID 2830812 DOI: 10.1164/ajrccm/137.3.630  0.537
1988 Selig WM, Burhop KE, Garcia JG, Malik AB. Substance P-induced pulmonary vasoreactivity in isolated perfused guinea pig lung. Circulation Research. 62: 196-203. PMID 2448056 DOI: 10.1161/01.RES.62.2.196  0.322
1987 Malik AB, Lo SK. Thrombin-endothelial interactions: role in lung vascular permeability. Molecular Aspects of Medicine. 8: 515-54. PMID 3916278 DOI: 10.1016/0098-2997(85)90013-5  0.334
1987 Burhop KE, Garcia JG, Selig WM, Lo SK, van der Zee H, Kaplan JE, Malik AB. Platelet-activating factor increases lung vascular permeability to protein. Journal of Applied Physiology (Bethesda, Md. : 1985). 61: 2210-7. PMID 3804927 DOI: 10.1152/jappl.1986.61.6.2210  0.424
1987 Shepard JM, Goderie SK, Brzyski N, Del Vecchio PJ, Malik AB, Kimelberg HK. Effects of alterations in endothelial cell volume on transendothelial albumin permeability. Journal of Cellular Physiology. 133: 389-94. PMID 3680396 DOI: 10.1002/jcp.1041330226  0.334
1987 Minnear FL, Martin D, Hill L, Taylor AE, Malik AB. Lung morphological and permeability changes induced by intravascular coagulation in dogs. The American Journal of Physiology. 253: H634-44. PMID 3631298 DOI: 10.1152/ajpheart.1987.253.3.h634  0.402
1987 Malik AB, Horgan MJ. Mechanisms of thrombin-induced lung vascular injury and edema. The American Review of Respiratory Disease. 136: 467-70. PMID 3619210 DOI: 10.1164/ajrccm/136.2.467  0.39
1987 Malik AB. Role of fibrin-neutrophil interactions in lung vascular injury Progress in Clinical and Biological Research. 236: 33-42. PMID 3615438  0.326
1987 Burhop KE, Selig WM, Beeler DA, Malik AB. Effect of heparin on increased pulmonary microvascular permeability after bone marrow embolism in awake sheep. The American Review of Respiratory Disease. 136: 134-41. PMID 3300440 DOI: 10.1164/ajrccm/136.1.134  0.335
1987 Johnson A, Lo SK, Blumenstock FB, Malik AB. CVF-induced decomplementation: effect on lung transvascular protein flux after thrombin. Journal of Applied Physiology (Bethesda, Md. : 1985). 62: 863-9. PMID 3032888 DOI: 10.1152/jappl.1987.62.3.863  0.625
1987 Perlman MB, Johnson A, Malik AB. Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. The American Journal of Physiology. 252: H605-14. PMID 3030141 DOI: 10.1152/ajpheart.1987.252.3.H605  0.635
1987 Johnson A, Cooper JA, Malik AB. Effect of complement activation with cobra venom factor on pulmonary vascular permeability. Journal of Applied Physiology (Bethesda, Md. : 1985). 61: 2202-9. PMID 3027023 DOI: 10.1152/jappl.1986.61.6.2202  0.655
1987 Johnson A, Perlman MB, Blumenstock FA, Malik AB. Superoxide dismutase prevents the thrombin-induced increase in lung vascular permeability: role of superoxide in mediating the alterations in lung fluid balance. Circulation Research. 59: 405-15. PMID 3024859 DOI: 10.1161/01.RES.59.4.405  0.662
1986 Noonan TC, Malik AB. Pulmonary vascular response to leukotriene D4 in unanesthetized sheep: role of thromboxane. Journal of Applied Physiology (Bethesda, Md. : 1985). 60: 765-9. PMID 3957828 DOI: 10.1152/jappl.1986.60.3.765  0.326
1986 Burhop KE, van Der Zee H, Bizios R, Kaplan JE, Malik AB. Pulmonary vascular response to platelet-activating factor in awake sheep and the role of cyclooxygenase metabolites American Review of Respiratory Disease. 134: 548-554. PMID 3752711 DOI: 10.1164/Arrd.1986.134.3.548  0.37
1986 Kern DF, Saldeen K, Saldeen T, Malik AB. Pulmonary vascular effects of a fibrin(ogen)-derived vasoactive peptide. Thrombosis Research. 42: 783-8. PMID 3726799 DOI: 10.1016/0049-3848(86)90114-3  0.313
1986 Perlman MB, Lo SK, Malik AB. Effect of prostacyclin on pulmonary vascular response to thrombin in awake sheep. Journal of Applied Physiology (Bethesda, Md. : 1985). 60: 546-53. PMID 3512510 DOI: 10.1152/jappl.1986.60.2.546  0.302
1986 Malik AB, Lo SK, Bizios R. Thrombin-induced alterations in endothelial permeability Annals of the New York Academy of Sciences. 293-309. PMID 3032047 DOI: 10.1111/J.1749-6632.1986.Tb34591.X  0.411
1986 Minnear FL, Johnson A, Malik AB. Beta-adrenergic modulation of pulmonary transvascular fluid and protein exchange. Journal of Applied Physiology (Bethesda, Md. : 1985). 60: 266-74. PMID 2867988 DOI: 10.1152/jappl.1986.60.1.266  0.61
1985 Garcia-Szabo R, Kern DF, Malik AB. Pulmonary vascular response to thrombin: effects of thromboxane synthetase inhibition with OKY-046 and OKY-1581. Prostaglandins. 28: 851-66. PMID 6543018 DOI: 10.1016/0090-6980(84)90039-X  0.393
1985 Lo SK, Perlman MB, Niehaus GD, Malik AB. Thrombin-induced alterations in lung fluid balance in awake sheep. Journal of Applied Physiology (Bethesda, Md. : 1985). 58: 1421-7. PMID 3997709 DOI: 10.1152/jappl.1985.58.5.1421  0.364
1985 Johnson A, Garcia-Szabo R, Kaplan JE, Malik AB. Fibrin degradation products increase lung transvascular fluid filtration after thrombin-induced pulmonary microembolism. Thrombosis Research. 37: 543-54. PMID 3983909 DOI: 10.1016/0049-3848(85)90100-8  0.612
1985 Malik AB, Selig WM, Burhop KE. Cellular and humoral mediators of pulmonary edema. Lung. 163: 193-219. PMID 3930896 DOI: 10.1007/BF02713821  0.308
1985 Johnson A, Malik AB. Pulmonary transvascular fluid and protein exchange after thrombin-induced microembolism. Differential effects of cyclooxygenase inhibitors. The American Review of Respiratory Disease. 132: 70-6. PMID 3925828 DOI: 10.1164/arrd.1985.132.1.70  0.555
1985 Kern DF, Malik AB. Microvascular albumin permeability in isolated perfused lung: effects of EDTA. Journal of Applied Physiology (Bethesda, Md. : 1985). 58: 372-5. PMID 3920186 DOI: 10.1152/jappl.1985.58.2.372  0.328
1985 Noonan TC, Kern DF, Malik AB. Pulmonary microcirculatory responses to leukotrienes B4, C4 and D4 in sheep. Prostaglandins. 30: 419-34. PMID 2997844 DOI: 10.1016/0090-6980(85)90116-9  0.345
1985 Malik AB. Mechanisms of neurogenic pulmonary edema Circulation Research. 57: 1-18. PMID 2988816 DOI: 10.1161/01.RES.57.1.1  0.352
1985 Perlman MB, Lo SK, Malik AB. 1815 PULMONARY VASCULAR PERMEABILITY TO PROTEINS INCREASES AFTER THROMBIN-INDUCED INTRAVASCULAR COAGULATION Pediatric Research. 19: 413A-413A. DOI: 10.1203/00006450-198504000-01833  0.412
1985 Perlman M, Johnson A, Malik A. 1814 MEDIATORS AFFECTING NEUTROPHIL (PMN) FUNCTION ARE RELEASED AFTER PULMONARY INTRAVASCULAR COAGULATION Pediatric Research. 19: 413A-413A. DOI: 10.1203/00006450-198504000-01832  0.367
1984 Neumann PH, Kivlen CM, Johnson A, Minnear FL, Malik AB. Effect of alveolar hypoxia on regional pulmonary perfusion. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 56: 338-42. PMID 6706746 DOI: 10.1152/jappl.1984.56.2.338  0.579
1984 Johnson A, Blumenstock FA, Malik AB. Effect of complement depletion on lung fluid balance after thrombin. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 55: 1480-5. PMID 6643185 DOI: 10.1152/jappl.1983.55.5.1480  0.63
1984 Garcia-Szabo RR, Kern DF, Bizios R, Fenton JW, Minnear FL, Lo SK, Malik AB. Comparison of α- and γ-thrombin on lung fluid balance in anesthetized sheep Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 57: 1375-1383. PMID 6549181 DOI: 10.1152/Jappl.1984.57.5.1375  0.339
1984 Cooper JA, Solano SJ, Bizios R, Kaplan JE, Malik AB. Pulmonary neutrophil kinetics after thrombin-induced intravascular coagulation Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 57: 826-832. PMID 6436212 DOI: 10.1152/Jappl.1984.57.3.826  0.329
1984 Perlman M, Cooper J, Malik A. EFFECTS OF CYCLOOXYGENASE INHIBITORS ON LUNG MICROVASCULAR INJURY FOLLOWING PULMONARY INTRAVASCULAR COAGULATION (PIC) Pediatric Research. 18: 401A-401A. DOI: 10.1203/00006450-198404001-01846  0.405
1983 Johnson A, Malik AB. Effect of defibrinogenation on lung fluid and protein exchange after glass bead embolization. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 53: 895-900. PMID 7153124 DOI: 10.1152/jappl.1982.53.4.895  0.548
1983 Barie PS, Tahamont MV, Malik AB. Prevention of increased pulmonary vascular permeability after pancreatitis by granulocyte depletion in sheep. The American Review of Respiratory Disease. 126: 904-8. PMID 7149457 DOI: 10.1164/arrd.1982.126.5.904  0.327
1983 Tahamont MV, Malik AB. Granulocytes mediate the increase in pulmonary vascular permeability after thrombin embolism. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 54: 1489-95. PMID 6874470 DOI: 10.1152/jappl.1983.54.6.1489  0.374
1983 Johnson A, Tahamont MV, Malik AB. Thrombin-induced lung vascular injury. Roles of fibrinogen and fibrinolysis. The American Review of Respiratory Disease. 128: 38-44. PMID 6870068 DOI: 10.1164/ARRD.1983.128.1.38  0.636
1983 Malik AB, Johnson A, Tahamont MV, van der Zee H, Blumenstock FA. Role of blood components in mediating lung vascular injury after pulmonary vascular thrombosis. Chest. 83: 21S-24S. PMID 6839843 DOI: 10.1378/chest.83.5_Supplement.21S  0.625
1983 van der Zee H, Neumann PH, Minnear FL, Malik AB. Effects of transient intracranial hypertension on lung fluid and protein exchange. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 54: 178-84. PMID 6826402 DOI: 10.1152/jappl.1983.54.1.178  0.344
1983 Malik AB, Johnson A, Blumenstock FA. Interaction between formed elements and the pulmonary endothelium. General Pharmacology. 14: 197-200. PMID 6826034 DOI: 10.1016/0306-3623(83)90102-7  0.553
1983 Garcia-Szabo RR, Peterson MB, Watkins WD, Bizios R, Kong DL, Malik AB. Thromboxane generation after thrombin. Protective effect of thromboxane synthetase inhibition on lung fluid balance. Circulation Research. 53: 214-22. PMID 6684001 DOI: 10.1161/01.Res.53.2.214  0.333
1983 Garcia Szabo RR, Minnear FL, Bizios R, Johnson A, Malik AB. Role of thromboxane in the pulmonary response to pulmonary microembolization Chest. 83. PMID 6682370 DOI: 10.1378/Chest.83.5_Supplement.76S  0.638
1983 Minnear FL, Barie PS, Malik AB. Effects of transient pulmonary hypertension on pulmonary vascular permeability. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 55: 983-9. PMID 6629932 DOI: 10.1152/jappl.1983.55.3.983  0.347
1983 Bizios R, Minnear FL, Van Der Zeee H, Malik AB. Effects of cyclooxygenase and lipoxygenase inhibition on lung fluid balance after thrombin Journal of Applied Physiology Respiratory Environmental and Exercise Physiology. 55: 462-471. PMID 6413464 DOI: 10.1152/Jappl.1983.55.2.462  0.312
1983 Malik AB, Minnear FL, Popp AJ. Catecholamine-induced pulmonary edema. General Pharmacology. 14: 55-60. PMID 6337921 DOI: 10.1016/0306-3623(83)90063-0  0.31
1983 Minnear FL, Kivlen CM, Malik AB. Effect of bradykinin on lung vascular permeability in sheep. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 55: 1079-84. PMID 6313565 DOI: 10.1152/jappl.1983.55.4.1079  0.352
1983 Kivlen CM, Johnson A, Pittman T, Guile AJ, Malik AB. Effect of converting enzyme inhibition on pulmonary edema after microembolization. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 53: 1546-50. PMID 6295992 DOI: 10.1152/jappl.1982.53.6.1546  0.607
1982 Barie PS, Malik AB. Effect of pulmonary arterial occlusion on lung fluid and protein exchange. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 53: 543-8. PMID 7129975 DOI: 10.1152/jappl.1982.53.3.543  0.308
1982 Johnson A, Tahamont MV, Kaplan JE, Malik AB. Lung fluid balance after pulmonary embolization: effects of thrombin vs. fibrin aggregates. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 52: 1565-70. PMID 7107466 DOI: 10.1152/jappl.1982.52.6.1565  0.643
1982 Johnson A, Malik AB. Pulmonary edema after glass bead microembolization: protective effect of granulocytopenia. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 52: 155-61. PMID 7061261 DOI: 10.1152/jappl.1982.52.1.155  0.571
1982 Malik AB, Johnson A, Tahamont MV. Mechanisms of lung vascular injury after intravascular coagulation. Annals of the New York Academy of Sciences. 384: 213-34. PMID 6953821 DOI: 10.1111/j.1749-6632.1982.tb21374.x  0.632
1982 Minnear FL, Moon DG, Kaplan JE, Malik AB. Effect of ADP-induced platelet aggregation on lung fluid balance in sheep. The American Journal of Physiology. 242: H645-51. PMID 6802000 DOI: 10.1152/ajpheart.1982.242.4.H645  0.356
1982 Malik A, Tahamont M, Minnear F, Johnson A, Kaplan J. Lung Fluid and Protein Exchange after Pulmonary Vascular Thrombosis Chest. 81: 54-56. DOI: 10.1378/chest.81.5_Supplement.54S  0.341
1981 Johnson A, Malik AB. Effect of granulocytopenia on extravascular lung water content after microembolization. The American Review of Respiratory Disease. 122: 561-6. PMID 7436121 DOI: 10.1164/arrd.1980.122.4.561  0.583
1981 Johnson A, Malik AB. Effect of defibrinogenation on lung water accumulation after pulmonary microembolism in dogs. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 49: 841-5. PMID 7429906 DOI: 10.1152/jappl.1980.49.5.841  0.593
1981 Lee BC, Malik AB, Barie PS, Minnear FL. Effect of acute pancreatitis on pulmonary transvascular fluid and protein exchange. The American Review of Respiratory Disease. 123: 618-21. PMID 7271055 DOI: 10.1164/arrd.1981.123.6.618  0.324
1981 Johnson A, Malik AB. Effects of different-size microemboli on lung fluid and protein exchange. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 51: 461-4. PMID 7263452 DOI: 10.1152/jappl.1981.51.2.461  0.628
1981 Minnear FL, Barrie PS, Malik AB. Effects of epinephrine and norepinephrine infusion on lung fluid balance in sheep. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 50: 1353-7. PMID 7263398 DOI: 10.1152/jappl.1981.50.6.1353  0.318
1980 Malik AB, van der Zee H, Johnson A. Inhibition of microembolization-induced pulmonary edema by early heparin treatment in dogs. Thrombosis Research. 18: 139-47. PMID 7404496 DOI: 10.1016/0049-3848(80)90178-4  0.587
1980 Johnson A, Malik AB. Effect of heparin on pulmonary edema after microembolization in rats. Thrombosis Research. 16: 329-33. PMID 515998 DOI: 10.1016/0049-3848(79)90080-X  0.548
1979 Malik AB, van der Zee H. Lung vascular permeability following progressive pulmonary embolization. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 45: 590-97. PMID 711576 DOI: 10.1152/jappl.1978.45.4.590  0.352
1979 Malik AB, Lee BC, van der Zee H, Johnson A. The role of fibrin in the genesis of pulmonary edema after embolization in dogs. Circulation Research. 45: 120-5. PMID 445693 DOI: 10.1161/01.RES.45.1.120  0.585
1978 Malik AB, van der Zee H. Mechanism of pulmonary edema induced by microembolization in dogs. Circulation Research. 42: 73-9. PMID 618604 DOI: 10.1161/01.RES.42.1.73  0.309
1977 Malik AB, van der Zee H. Thrombin induced pulmonary insufficiency. Thrombosis Research. 11: 497-506. PMID 918908 DOI: 10.1016/0049-3848(77)90203-1  0.314
1977 Malik AB, van der Zee H. Time course of pulmonary vascular response to microembolization. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology. 43: 51-8. PMID 893266 DOI: 10.1152/jappl.1977.43.1.51  0.307
1976 Malik AB, Kidd BS. Pulmonary arterial wedge and left atrial pressures and the site of hypoxic pulmonary vasoconstriction. Respiration; International Review of Thoracic Diseases. 33: 123-32. PMID 935675 DOI: 10.1159/000193725  0.698
1974 Malik AB, Kidd BS. Adrenergic blockade and the pulmonary vascular response to hypoxia. Respiration Physiology. 19: 96-106. PMID 4754997 DOI: 10.1016/0034-5687(73)90093-5  0.723
1973 Malik AB, Kidd BS. The independent effects of changes in H + and CO 2 concentrations on pulmonary hemodynamics of intact dogs Canadian Journal of Physiology and Pharmacology. 51: 139-147. PMID 4697732 DOI: 10.1139/y73-018  0.683
1973 Malik AB, Kidd BS. Independent effects of changes in H+ and CO 2 concentrations on hypoxic pulmonary vasoconstriction Journal of Applied Physiology. 34: 318-323. PMID 4688120 DOI: 10.1152/jappl.1973.34.3.318  0.681
1973 Malik AB, Kidd BS. Time course of pulmonary vascular response to hypoxia in dogs The American Journal of Physiology. 224: 1-6. PMID 4683301 DOI: 10.1152/ajplegacy.1973.224.1.1  0.714
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