Srinivas Tekkam, Ph.D. - Publications

Affiliations: 
2014 Chemistry Indiana University, Bloomington, Bloomington, IN, United States 
Area:
identification of novel antibacterial agents that function via inhibition of bacterial cell wall (peptidoglycan) biosynthesis, synthesis and biological study of novel agents for use in cancer chemotherapy

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 De Pascalis L, Tekkam S, Finn MG. Azanorbornadienes as Thiol-Reactive Cleavable Linkers. Organic Letters. 22: 6248-6251. PMID 32806178 DOI: 10.1021/Acs.Orglett.0C01912  0.323
2017 Hsu YP, Rittichier J, Kuru E, Yablonowski J, Pasciak E, Tekkam S, Hall E, Murphy B, Lee TK, Garner EC, Huang KC, Brun YV, VanNieuwenhze MS. Full color palette of fluorescent d-amino acids for in situ labeling of bacterial cell walls. Chemical Science. 8: 6313-6321. PMID 28989665 DOI: 10.1039/C7Sc01800B  0.659
2016 Liechti G, Kuru E, Packiam M, Hsu YP, Tekkam S, Hall E, Rittichier JT, VanNieuwenhze M, Brun YV, Maurelli AT. Pathogenic Chlamydia Lack a Classical Sacculus but Synthesize a Narrow, Mid-cell Peptidoglycan Ring, Regulated by MreB, for Cell Division. Plos Pathogens. 12: e1005590. PMID 27144308 DOI: 10.1371/Journal.Ppat.1005590  0.629
2015 Kuru E, Tekkam S, Hall E, Brun YV, Van Nieuwenhze MS. Synthesis of fluorescent D-amino acids and their use for probing peptidoglycan synthesis and bacterial growth in situ. Nature Protocols. 10: 33-52. PMID 25474031 DOI: 10.1038/Nprot.2014.197  0.757
2013 Tekkam S, Alam MA, Just MJ, Berry SM, Johnson JL, Jonnalagadda SC, Mereddy VR. Stereoselective synthesis of pyroglutamate natural product analogs from α- aminoacids and their anti-cancer evaluation. Anti-Cancer Agents in Medicinal Chemistry. 13: 1514-30. PMID 23848201 DOI: 10.2174/18715206113139990097  0.354
2013 Tekkam S, Johnson JL, Jonnalagadda SC, Mereddy VR. Concise synthesis of α-methylene-β-hydroxy-γ-carboxy- γ-lactams Journal of Heterocyclic Chemistry. 50: 955-958. DOI: 10.1002/Jhet.1578  0.35
2013 Tekkam S, Johnson JL, Jonnalagadda SC, Mereddy VR. An efficient synthesis of [2.2.1] heterobicyclic pyroglutamates Journal of Heterocyclic Chemistry. 50: 969-972. DOI: 10.1002/Jhet.1097  0.455
2012 Kuru E, Hughes HV, Brown PJ, Hall E, Tekkam S, Cava F, de Pedro MA, Brun YV, VanNieuwenhze MS. In Situ probing of newly synthesized peptidoglycan in live bacteria with fluorescent D-amino acids. Angewandte Chemie (International Ed. in English). 51: 12519-23. PMID 23055266 DOI: 10.1002/Anie.201206749  0.766
2012 Kuru E, Hughes HV, Brown PJ, Hall E, Tekkam S, Cava F, de Pedro MA, Brun YV, VanNieuwenhze MS. Inside Cover: In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with FluorescentD-Amino Acids (Angew. Chem. Int. Ed. 50/2012) Angewandte Chemie International Edition. 51: 12378-12378. DOI: 10.1002/Anie.201209051  0.749
2012 Kuru E, Hughes HV, Brown PJ, Hall E, Tekkam S, Cava F, de Pedro MA, Brun YV, VanNieuwenhze MS. Innentitelbild: In Situ Probing of Newly Synthesized Peptidoglycan in Live Bacteria with FluorescentD-Amino Acids (Angew. Chem. 50/2012) Angewandte Chemie. 124: 12546-12546. DOI: 10.1002/Ange.201209051  0.752
2011 Tekkam S, Alam MA, Jonnalagadda SC, Mereddy VR. Novel methodologies for the synthesis of functionalized pyroglutamates. Chemical Communications (Cambridge, England). 47: 3219-21. PMID 21318205 DOI: 10.1039/C0Cc05609J  0.369
2011 Just MJ, Tekkam S, Alam MA, Jonnalagadda SC, Johnson JL, Mereddy VR. Stereoselective synthesis of functionalized pyroglutamates Tetrahedron Letters. 52: 5349-5351. DOI: 10.1016/J.Tetlet.2011.08.029  0.331
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