Waldemar Debinski - Publications

Affiliations: 
Molecular Genetics & Genomics Wake Forest University, Winston-Salem, NC, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Abdulhaleem M, Ruiz J, O'Neill S, Hughes RT, Qasem S, Strowd RE, Furdui C, Watabe K, Miller LD, Debinski W, Tatter S, Metheny-Barlow L, White JJ, Lee J, McTyre ER, et al. Collagen deposition within brain metastases is associated with leptomeningeal failure after 
cavity-directed radiosurgery. Neuro-Oncology Advances. 5: vdac186. PMID 36789023 DOI: 10.1093/noajnl/vdac186  0.435
2022 Lyu Q, Namjoshi SV, McTyre E, Topaloglu U, Barcus R, Chan MD, Cramer CK, Debinski W, Gurcan MN, Lesser GJ, Lin HK, Munden RF, Pasche BC, Sai KKS, Strowd RE, et al. A transformer-based deep-learning approach for classifying brain metastases into primary organ sites using clinical whole-brain MRI images. Patterns (New York, N.Y.). 3: 100613. PMID 36419451 DOI: 10.1016/j.patter.2022.100613  0.457
2022 Helis CA, Prim SN, Cramer CK, Strowd R, Lesser GJ, White JJ, Tatter SB, Laxton AW, Whitlow C, Lo HW, Debinski W, Ververs JD, Black PJ, Chan MD. Clinical outcomes of dose-escalated re-irradiation in patients with recurrent high-grade glioma. Neuro-Oncology Practice. 9: 390-401. PMID 36134018 DOI: 10.1093/nop/npac032  0.437
2020 Sharma P, Sonawane P, Herpai D, D'Agostino R, Rossmeisl J, Tatter S, Debinski W. Multireceptor targeting of glioblastoma. Neuro-Oncology Advances. 2: vdaa107. PMID 33150335 DOI: 10.1093/noajnl/vdaa107  0.537
2020 Renfrow JJ, Soike MH, West JL, Ramkissoon SH, Metheny-Barlow L, Mott RT, Kittel CA, D'Agostino RB, Tatter SB, Laxton AW, Frenkel MB, Hawkins GA, Herpai D, Sanders S, Sarkaria JN, ... ... Debinski W, et al. Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor. Scientific Reports. 10: 15195. PMID 32938997 DOI: 10.1038/S41598-020-72290-2  0.553
2020 Hassan MS, Pullikuth A, Nelson KC, Flores A, Karpova Y, Baiz D, Zhu S, Sui G, Huang Y, D'Agostino R, Hemal A, von Holzen U, Debinski W, Kulik G. Beta2-adrenoreceptor signaling increases therapy-resistance in prostate cancer by upregulating MCL1. Molecular Cancer Research : McR. PMID 32928910 DOI: 10.1158/1541-7786.Mcr-19-1037  0.328
2020 Rossmeisl JH, Herpai D, Quigley M, Cecere TE, Robertson JL, D'Agostino RB, Hinckley J, Tatter SB, Dickinson PJ, Debinski W. Phase I trial of convection-enhanced delivery of IL13RA2 and EPHA2 receptor targeted cytotoxins in dogs with spontaneous intracranial gliomas. Neuro-Oncology. PMID 32812637 DOI: 10.1093/Neuonc/Noaa196  0.569
2020 Werner CK, Nna UJ, Sun H, Wilder-Romans K, Dresser J, Kothari AU, Zhou W, Yao Y, Rao A, Stallard S, Koschmann C, Bor T, Debinski W, Hegedus AM, Morgan MA, et al. Expression of the of the androgen receptor governs radiation resistance in a subset of glioblastomas vulnerable to anti-androgen therapy. Molecular Cancer Therapeutics. PMID 32796101 DOI: 10.1158/1535-7163.Mct-20-0095  0.344
2020 Sharma P, Roberts C, Herpai D, Fokt ID, Priebe W, Debinski W. Drug Conjugates for Targeting Eph Receptors in Glioblastoma. Pharmaceuticals (Basel, Switzerland). 13. PMID 32340173 DOI: 10.3390/Ph13040077  0.426
2020 Sanders S, Debinski W. Challenges to Successful Implementation of the Immune Checkpoint Inhibitors for Treatment of Glioblastoma. International Journal of Molecular Sciences. 21. PMID 32316096 DOI: 10.3390/Ijms21082759  0.311
2019 Soike MH, Logue J, Qasem S, Hughes RT, McTyre E, Su J, Triozzi P, Bendandi M, Lo HW, Ahmed T, O'Neill SS, Debinski W, Pasche B, Watabe K, Miller LD, et al. CD138 plasma cells may predict brain metastasis recurrence following resection and stereotactic radiosurgery. Scientific Reports. 9: 14385. PMID 31591443 DOI: 10.1038/S41598-019-50298-7  0.318
2019 Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Regua AT, Arrigo A, Anguelov M, ... ... Debinski W, et al. TGLI1 transcription factor mediates breast cancer brain metastasis via activating metastasis-initiating cancer stem cells and astrocytes in the tumor microenvironment. Oncogene. PMID 31462709 DOI: 10.1038/S41388-019-0959-3  0.349
2019 Sirkisoon SR, Carpenter RL, Rimkus T, Doheny D, Zhu D, Aguayo NR, Anguelov M, Arrigo A, Xing F, Chan M, Ruiz J, Metheny-Barlow LJ, Strowd R, Lin J, Pasche BC, ... Debinski W, et al. Abstract 3689: Tumor-specific gain-of-function tGLI1 transcription factor is a novel mediator of breast cancer stem cells and a novel transcriptional activator of cancer stemness genes Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3689  0.3
2019 Rimkus TK, Zhu D, Carpenter RL, Paw I, Arrigo A, Sirkisoon S, Doheny D, Aguayo N, Lee J, Jin G, Spooner E, Pasche B, Debinski W, Lo H. Abstract 3481: Roles of tumor suppressor candidate 2 (TUSC2) in glioblastoma progression and gliomagenesis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3481  0.312
2019 Sharma P, Herpai D, Rossmeisl J, Tatter S, Debinski W. Exth-54. Multivalent Targeted Proteins For Glioblastoma Treatment Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.385  0.509
2019 Sanders S, Herpai D, Miller L, Debinski W. TMIC-36. ALDH1A2 AS A NOVEL PUTATIVE MARKER OF MACROPHAGE DIFFERENTIATION IN GBM Neuro-Oncology. 21: vi255-vi255. DOI: 10.1093/Neuonc/Noz175.1070  0.323
2018 Mao C, Li F, Zhao Y, Debinski W, Ming X. P-glycoprotein-targeted photodynamic therapy boosts cancer nanomedicine by priming tumor microenvironment. Theranostics. 8: 6274-6290. PMID 30613297 DOI: 10.7150/Thno.29580  0.409
2018 Sharma P, Debinski W. Receptor-Targeted Glial Brain Tumor Therapies. International Journal of Molecular Sciences. 19. PMID 30366424 DOI: 10.3390/Ijms19113326  0.417
2018 Soike MH, McTyre ER, Shah N, Puchalski RB, Holmes JA, Paulsson AK, Miller LD, Cramer CK, Lesser GJ, Strowd RE, Hinson WH, Mott RT, Johnson AJ, Lo HW, Laxton AW, ... ... Debinski W, et al. Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns? Neuroradiology. PMID 30094640 DOI: 10.1007/S00234-018-2060-Y  0.503
2018 Renfrow JJ, Soike MH, Debinski W, Ramkissoon SH, Mott RT, Frenkel MB, Sarkaria JN, Lesser GJ, Strowd RE. Hypoxia-inducible factor 2α: a novel target in gliomas. Future Medicinal Chemistry. PMID 30089425 DOI: 10.4155/Fmc-2018-0163  0.345
2018 Mao C, Zhao Y, Li F, Li Z, Tian S, Debinski W, Ming X. P-glycoprotein targeted and near-infrared light-guided depletion of chemoresistant tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30081143 DOI: 10.1016/J.Jconrel.2018.08.005  0.37
2018 Xing F, Liu Y, Wu SY, Wu K, Sharma S, Mo YY, Feng J, Sanders S, Jin G, Singh R, Vidi PA, Tyagi A, Chan MD, Ruiz J, Debinski W, et al. Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis. Cancer Research. PMID 30026327 DOI: 10.1158/0008-5472.Can-18-1102  0.366
2018 Rimkus TK, Carpenter RL, Sirkisoon SR, Zhu D, Pasche B, Chan MD, Lesser GJ, Tatter SB, Watabe K, Debinski W, Lo HW. Truncated glioma-associated oncogene homolog 1 (tGLI1) mediates mesenchymal glioblastoma via transcriptional activation of CD44. Cancer Research. PMID 29463580 DOI: 10.1158/0008-5472.Can-17-2933  0.552
2018 Jimenez H, Blackman C, Lesser G, Debinski W, Chan M, Sharma S, Watabe K, Lo HW, Thomas A, Godwin D, Blackstock W, Mudry A, Posey J, O'Connor R, Brezovich I, et al. Use of non-ionizing electromagnetic fields for the treatment of cancer. Frontiers in Bioscience (Landmark Edition). 23: 284-297. PMID 28930547 DOI: 10.2741/4591  0.357
2018 Zielinski R, Tworowska I, Skora S, Rusin A, Venugopal R, Jayakumar A, Fokt I, Kang Y, Fleming J, Huang Y, Herpai D, Debinski W, Priebe W. Abstract 1927: Targeting IL-13RA2 in melanoma and pancreatic cancer Cancer Research. 78: 1927-1927. DOI: 10.1158/1538-7445.Am2018-1927  0.37
2018 Rossmeisl J, Herpai D, Robertson J, Dickinson P, Tatter S, Debinski W. EXTH-43. EFFECTIVE TREATMENT OF CANINE SPONTANEOUS GLIOMAS WITH A CYTOTOXIC COCKTAIL TARGETING IL-13RA2 AND EphA2 RECEPTORS Neuro-Oncology. 20: vi94-vi94. DOI: 10.1093/Neuonc/Noy148.391  0.546
2018 Sharma P, Herpai D, Rossmeisl J, Tatter S, Debinski W. EXTH-29. MULTI-RECEPTOR TARGETING IN GBM Neuro-Oncology. 20: vi91-vi91. DOI: 10.1093/Neuonc/Noy148.378  0.526
2017 Carpenter RL, Sirkisoon S, Zhu D, Rimkus T, Harrison A, Anderson A, Paw I, Qasem S, Xing F, Liu Y, Chan M, Metheny-Barlow L, Pasche BC, Debinski W, Watabe K, et al. Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth. Oncotarget. 8: 73947-73963. PMID 29088759 DOI: 10.18632/Oncotarget.18166  0.305
2017 Sai KKS, Sattiraju A, Almaguel FG, Xuan A, Rideout S, Krishnaswamy RS, Zhang J, Herpai DM, Debinski W, Mintz A. Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker. Oncotarget. 8: 50997-51007. PMID 28881623 DOI: 10.18632/Oncotarget.16549  0.376
2017 Sonawane P, Choi YA, Pandya H, Herpai DM, Fokt I, Priebe W, Debinski W. Novel Molecular Multilevel Targeted Antitumor Agents. Cancer Translational Medicine. 3: 69-79. PMID 28825042 DOI: 10.4103/Ctm.Ctm_12_17  0.612
2017 Ivey JW, Latouche EL, Richards ML, Lesser GJ, Debinski W, Davalos RV, Verbridge SS. Enhancing Irreversible Electroporation by Manipulating Cellular Biophysics with a Molecular Adjuvant. Biophysical Journal. 113: 472-480. PMID 28746857 DOI: 10.1016/J.Bpj.2017.06.014  0.348
2017 Sattiraju A, Sai KKS, Xuan A, Pandya DN, Almaguel FG, Wadas TJ, Herpai DM, Debinski W, Mintz A. IL13RA2 targeted alpha particle therapy against glioblastomas. Oncotarget. PMID 28562337 DOI: 10.18632/Oncotarget.17792  0.349
2017 Rossmeisl JH, Hall-Manning K, Robertson JL, King JN, Davalos RV, Debinski W, Elankumaran S. Expression and activity of the urokinase plasminogen activator system in canine primary brain tumors. Oncotargets and Therapy. 10: 2077-2085. PMID 28442916 DOI: 10.2147/Ott.S132964  0.361
2017 McTyre E, Lucas JT, Helis C, Farris M, Soike M, Mott R, Laxton AW, Tatter SB, Lesser GJ, Strowd RE, Lo HW, Debinski W, Chan MD. Outcomes for Anaplastic Glioma Treated With Radiation Therapy With or Without Concurrent Temozolomide. American Journal of Clinical Oncology. PMID 28301347 DOI: 10.1097/Coc.0000000000000380  0.49
2017 Renfrow J, Mott R, Huang Y, Wong T, Lesser GJ, Debinski W, Strowd RE. In situ expression of hypoxia inducible factor 2-alpha in gliomas. Journal of Clinical Oncology. 35: e13534-e13534. DOI: 10.1200/Jco.2017.35.15_Suppl.E13534  0.313
2017 Sattiraju A, Xuan A, Almaguel F, Herpai D, Debinski W, Mintz A, Sai KKS. Abstract 1831: PET/CT imaging of interleukin-13 receptor alpha-2-targeted peptide to glioblastoma after locoregional delivery Cancer Research. 77: 1831-1831. DOI: 10.1158/1538-7445.Am2017-1831  0.35
2017 Sonawane P, Herpai D, Ferluga S, Tatter SB, Debinski W. P08.13 A single pharmaceutic agent for molecular resection of Glioblastoma Neuro-Oncology. 19: iii56-iii56. DOI: 10.1093/Neuonc/Nox036.203  0.474
2017 Rossmeisl JH, Herpai D, Robertson JL, Dickinson PJ, Tatter SB, Debinski W. P08.12 Tolerability and initial efficacy of convection-enhanced delivery of combinatorial IL-13RA2 and EphA2 targeted cytotoxins to dogs with spontaneous intracranial malignant gliomas Neuro-Oncology. 19: iii56-iii56. DOI: 10.1093/Neuonc/Nox036.202  0.535
2016 Hughes RT, Black PJ, Page BR, Lucas JT, Qasem SA, Watabe K, Ruiz J, Laxton AW, Tatter SB, Debinski W, Chan MD. Local control of brain metastases after stereotactic radiosurgery: the impact of whole brain radiotherapy and treatment paradigm. Journal of Radiosurgery and Sbrt. 4: 89-96. PMID 29296433  0.435
2016 Stuart CH, Riley KR, Boyacioglu O, Herpai DM, Debinski W, Qasem S, Marini FC, Colyer CL, Gmeiner WH. Selection of a Novel Aptamer Against Vitronectin Using Capillary Electrophoresis and Next Generation Sequencing. Molecular Therapy. Nucleic Acids. 5: e386. PMID 27845768 DOI: 10.1038/Mtna.2016.91  0.324
2016 Randolph DM, McTyre ER, Paulsson AK, Holmes JA, Hinson WH, Lesser GJ, Strowd R, Lo HW, Laxton AW, Tatter SB, Debinski W, Chan MD. Impact of timing of radiotherapy in patients with newly diagnosed glioblastoma. Clinical Neurology and Neurosurgery. 151: 73-78. PMID 27816029 DOI: 10.1016/J.Clineuro.2016.10.012  0.489
2016 Soike M, McTyre E, Holmes JA, Paulsson AK, Miller L, Lesser GJ, Strowd RE, Johnson A, Lo HW, Laxton AW, Tatter SB, Debinski W, Chan MD. Genomic Predictors of Imaging Response and Survival in Glioblastoma. International Journal of Radiation Oncology, Biology, Physics. 96: E121-E122. PMID 27673833 DOI: 10.1016/J.Ijrobp.2016.06.895  0.463
2016 Ferluga S, Tomé CM, Herpai DM, D'Agostino R, Debinski W. Simultaneous targeting of Eph receptors in glioblastoma. Oncotarget. PMID 27494882 DOI: 10.18632/Oncotarget.10978  0.422
2016 Jimenez H, Wang M, Sharma S, Herpai D, Lesser GJ, Debinski W, Costa F, Barbault A, Blackman C, Pasche B. EXTH-41. THE ANTI-PROLIFERATIVE EFFECTS OF RF EMF AMPLITUDE-MODULATED (AM RF EMF) AT TUMOR SPECIFIC FREQUENCIES ON GLIOBLASTOMA CELLS Neuro-Oncology. 18: vi68-vi68. DOI: 10.1093/Neuonc/Now212.285  0.304
2015 Rodriguez A, Tatter SB, Debinski W. Neurosurgical Techniques for Disruption of the Blood-Brain Barrier for Glioblastoma Treatment. Pharmaceutics. 7: 175-87. PMID 26247958 DOI: 10.3390/Pharmaceutics7030175  0.509
2015 Holmes JA, Paulsson AK, Page BR, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD. Genomic predictors of patterns of progression in glioblastoma and possible influences on radiation field design. Journal of Neuro-Oncology. 124: 447-53. PMID 26186902 DOI: 10.1007/S11060-015-1858-2  0.486
2015 Johnson AG, Ruiz J, Hughes R, Page BR, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, et al. Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases. Oncotarget. PMID 26087184 DOI: 10.18632/Oncotarget.4153  0.536
2015 Paw I, Carpenter RC, Watabe K, Debinski W, Lo HW. Mechanisms regulating glioma invasion. Cancer Letters. 362: 1-7. PMID 25796440 DOI: 10.1016/J.Canlet.2015.03.015  0.369
2015 Carpenter RL, Paw I, Sirkisoon S, Xing F, Gibo D, Watabe K, Debinski W, Lo H. Abstract 4165: The gain-of-function truncated GLI1 (TGLI1) promotes glioblastoma angiogenesis by direct upregulation of VEGF-C and TEM7 expression Cancer Research. 75: 4165-4165. DOI: 10.1158/1538-7445.Am2015-4165  0.341
2015 Sonawane P, Ferluga S, Herpai D, Debinski W. ATPS-81SINGLE-AGENT TARGETING OF Eph RECEPTORS A2, A3, B2 AND INTERLUKIN-13 RECEPTOR ALPHA 2 IN GLIOBLASTOMA Neuro-Oncology. 17: v36.2-v36. DOI: 10.1093/Neuonc/Nov204.81  0.436
2015 Herpai D, Ferluga S, Debinski W. ATPS-24MULTI-COMPARTMENTAL TARGETING OF GLIOBLASTOMA THROUGH THE EphA3 RECEPTOR Neuro-Oncology. 17: v23.2-v23. DOI: 10.1093/Neuonc/Nov204.24  0.434
2015 Holmes JA, Paulsson AK, Page BR, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD. Genomic predictors of patterns of progression in glioblastoma and possible influences on radiation field design Journal of Neuro-Oncology. DOI: 10.1007/s11060-015-1858-2  0.404
2015 Johnson AG, Ruiz J, Hughes R, Brandi RP, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, et al. Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases Oncotarget. 6: 18945-18955.  0.452
2014 Ferluga S, Debinski W. Ephs and Ephrins in malignant gliomas. Growth Factors (Chur, Switzerland). 32: 190-201. PMID 25418012 DOI: 10.3109/08977194.2014.985787  0.395
2014 Paulsson AK, Holmes JA, Peiffer AM, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD. Comparison of clinical outcomes and genomic characteristics of single focus and multifocal glioblastoma. Journal of Neuro-Oncology. 119: 429-35. PMID 24990827 DOI: 10.1007/S11060-014-1515-1  0.516
2014 Rossmeisl JH, Garcia PA, Daniel GB, Bourland JD, Debinski W, Dervisis N, Klahn S. Invited review--neuroimaging response assessment criteria for brain tumors in veterinary patients. Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. 55: 115-32. PMID 24219161 DOI: 10.1111/Vru.12118  0.334
2014 Paulsson AK, McMullen KP, Peiffer AM, Hinson WH, Kearns WT, Johnson AJ, Lesser GJ, Ellis TL, Tatter SB, Debinski W, Shaw EG, Chan MD. Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma. American Journal of Clinical Oncology. 37: 177-81. PMID 23211224 DOI: 10.1097/Coc.0B013E318271Ae03  0.495
2014 Rodriguez A, Gibo D, Debinski W. ME-18 * INDUCTION OF M2 TYPE MACROPHAGES BY GBM CELLS Neuro-Oncology. 16: v123-v123. DOI: 10.1093/Neuonc/Nou261.17  0.347
2014 Ferluga S, Gibo D, Debinski W. BI-09 * EphA3 RECEPTOR IS A MOLECULAR TARGET EXPRESSED IN MULTIPLE COMPARTMENTS OF GBM Neuro-Oncology. 16: v25-v25. DOI: 10.1093/Neuonc/Nou239.9  0.415
2014 Debinski W, Rodriguez A, Gibo D, Tatter SB, Mott R, Lively M, Miller L, Seals DF. FUNCTIONAL PRESENCE OF M2 MACROPHAGE MARKERS IN GBM TUMOR CELLS Neuro-Oncology. 16: iii40-iii41. DOI: 10.1093/Neuonc/Nou208.66  0.536
2014 Randolph D, Peiffer A, Paulsson A, Hinson W, Laxton A, Tatter S, Debinski W, Chan M. Does Delay of Start of Radiation Affect Clinical Outcomes of Glioblastoma International Journal of Radiation Oncology*Biology*Physics. 90: S295. DOI: 10.1016/J.Ijrobp.2014.05.994  0.468
2014 Holmes J, Paulsson A, Peiffer A, Miller L, Xu J, Hinson W, Lesser G, Tatter S, Debinski W, Chan M. Genomic Predictors of Infield and Marginal Failure for Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide: A Step Towards Personalized Radiation Fields? International Journal of Radiation Oncology*Biology*Physics. 90: S291-S292. DOI: 10.1016/J.Ijrobp.2014.05.985  0.475
2013 Baiz D, Hassan S, Choi YA, Flores A, Karpova Y, Yancey D, Pullikuth A, Sui G, Sadelain M, Debinski W, Kulik G. Combination of the PI3K inhibitor ZSTK474 with a PSMA-targeted immunotoxin accelerates apoptosis and regression of prostate cancer. Neoplasia (New York, N.Y.). 15: 1172-83. PMID 24204196 DOI: 10.1593/Neo.13986  0.339
2013 Debinski W, Dickinson P, Rossmeisl JH, Robertson J, Gibo DM. New agents for targeting of IL-13RA2 expressed in primary human and canine brain tumors. Plos One. 8: e77719. PMID 24147065 DOI: 10.1371/Journal.Pone.0077719  0.379
2013 Nguyen V, Zhu D, Conyers JM, Debinski W, Mintz A. Abstract 2150: Therapeutic efficacy of an optimized quadruply mutated IL13-based bacterial cytotoxin in an orthotopic murine glioma model. Cancer Research. 73: 2150-2150. DOI: 10.1158/1538-7445.Am2013-2150  0.442
2013 Campian J, Gladstone D, Ambady P, Ye X, King K, Borrello I, Petrik S, Golightly M, Holdhoff M, Grossman S, Bhardwaj R, Chakravadhanula M, Ozols V, Georges J, Carlson E, ... ... Debinski W, et al. IMMUNOTHERAPY/BIOLOGICAL THERAPIES Neuro-Oncology. 15: iii68-iii74. DOI: 10.1093/Neuonc/Not178  0.546
2013 Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Debinski W, ... ... Debinski W, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176  0.55
2012 Nguyen V, Conyers JM, Zhu D, Gibo DM, Hantgan RR, Larson SM, Debinski W, Mintz A. A novel ligand delivery system to non-invasively visualize and therapeutically exploit the IL13Rα2 tumor-restricted biomarker. Neuro-Oncology. 14: 1239-53. PMID 22952195 DOI: 10.1093/Neuonc/Nos211  0.427
2012 Beauchamp A, Lively MO, Mintz A, Gibo D, Wykosky J, Debinski W. EphrinA1 is released in three forms from cancer cells by matrix metalloproteases. Molecular and Cellular Biology. 32: 3253-64. PMID 22688511 DOI: 10.1128/Mcb.06791-11  0.75
2012 Pandya H, Debinski W. Toward intracellular targeted delivery of cancer therapeutics: progress and clinical outlook for brain tumor therapy. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 26: 235-44. PMID 22671766 DOI: 10.2165/11631600-000000000-00000  0.642
2012 Lema Tomé CM, Palma E, Ferluga S, Lowther WT, Hantgan R, Wykosky J, Debinski W. Structural and functional characterization of monomeric EphrinA1 binding site to EphA2 receptor. The Journal of Biological Chemistry. 287: 14012-22. PMID 22362770 DOI: 10.1074/Jbc.M111.311670  0.352
2012 Beauchamp A, Debinski W. Ephs and ephrins in cancer: ephrin-A1 signalling. Seminars in Cell & Developmental Biology. 23: 109-15. PMID 22040911 DOI: 10.1016/J.Semcdb.2011.10.019  0.749
2012 Pandya H, Gibo DM, Garg S, Kridel S, Debinski W. An interleukin 13 receptor α 2-specific peptide homes to human Glioblastoma multiforme xenografts. Neuro-Oncology. 14: 6-18. PMID 21946118 DOI: 10.1093/Neuonc/Nor141  0.622
2012 Debinski W. Opinion and Evidence in Cancer American Journal of Cancer. 1: 435-440. DOI: 10.2165/00024669-200201060-00006  0.3
2012 Ferluga S, Debinski W. Abstract 3860: Glycosylation is indispensable for ephrin A1 activity Cancer Research. 72: 3860-3860. DOI: 10.1158/1538-7445.Am2012-3860  0.424
2012 Brognaro E, Ghods A, Feinstein D, Glick R, Connolly KJ, Meetze K, Boudrow A, Gyuris J, Han M, Hingtgen S, Figueiredo J, Farrar C, Farrar C, Deubgen M, Martinez-Quintanilla J, ... ... Debinski W, et al. LAB-TUMOR MODELS (IN VIVO/IN VITRO) Neuro-Oncology. 14: vi160-vi164. DOI: 10.1093/Neuonc/Nos241  0.301
2012 Kijima N, Hosen N, Kagawa N, Hashimoto N, Chiba Y, Kinoshita M, Sugiyama H, Yoshimine T, Kim YZ, Kim KH, Lee EH, Hu B, Sim H, Mohan N, Agudelo-Garcia P, ... ... Debinski W, ... ... Debinski W, et al. LAB-CELL BIOLOGY AND SIGNALING Neuro-Oncology. 14: vi7-vi20. DOI: 10.1093/Neuonc/Nos220  0.739
2012 Proescholdt MA, Merrill MJ, Stoerr E, Lohmeier A, Brawanski A, Sim H, Hu B, Pineda CA, Yoon S, Viapiano MS, Rajappa P, Cobb WS, Huang Y, Lyden DC, Bromberg J, ... ... Debinski W, et al. LAB-ANGIOGENESIS AND INVASION Neuro-Oncology. 14: vi1-vi6. DOI: 10.1093/Neuonc/Nos219  0.317
2012 Pandya H, Debinski W. Toward Intracellular Targeted Delivery of Cancer Therapeutics Biodrugs. 26: 235-244. DOI: 10.1007/Bf03261882  0.634
2011 Nguyen V, Conyers JM, Zhu D, Gibo DM, Dorsey JF, Debinski W, Mintz A. IL-13Rα2-Targeted Therapy Escapees: Biologic and Therapeutic Implications. Translational Oncology. 4: 390-400. PMID 22191003 DOI: 10.1593/Tlo.11175  0.422
2011 Debinski W, Gibo DM. Fos-related antigen 1 (Fra-1) pairing with and transactivation of JunB in GBM cells. Cancer Biology & Therapy. 11: 254-62. PMID 21088499 DOI: 10.4161/Cbt.11.2.13953  0.355
2011 Gonzalez OA, Seals D, Debinski W. Abstract LB-115: EphA2/ephrinA1 system may regulate invadopodia formation of glioblastoma multiforme (GBM) cells Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-115  0.318
2011 Pandya H, Garg S, Gibo DM, Kridel SJ, Debinski W. Abstract 4141: A heptapeptide specific for Interleukin 13 receptor alpha 2 homes to the receptor-positive human GBM xenografts Cancer Research. 71: 4141-4141. DOI: 10.1158/1538-7445.Am2011-4141  0.606
2011 Nguyen V, Conyers JM, Zhu D, Hantgan RR, Debinski W, Mintz A. Abstract 3639: In vivo targeting of a Glioblastoma Multiforme restricted biomarker Cancer Research. 71: 3639-3639. DOI: 10.1158/1538-7445.Am2011-3639  0.418
2011 Baiz D, Yancey D, Choi YA, Baurin V, Karpova Y, Hassan S, Debinski W, Kulik G. Abstract 183: Loss of Bad phosphorylation and Mcl-1 expression is necessary for rapid apoptosisinduced by combination of TGFα-PE and ZSTK474 in prostate cancer cells Cancer Research. 71: 183-183. DOI: 10.1158/1538-7445.Am2011-183  0.312
2011 Conyers JM, Nguyen V, Murphy T, Beauchamp AS, Hantgan RR, Debinski W, Mintz A. Abstract 1650: Combinatorial targeting of GBM: A means of therapeutically overcoming tumor heterogeneity Cancer Research. 71: 1650-1650. DOI: 10.1158/1538-7445.Am2011-1650  0.768
2011 Beauchamp A, Wykosky J, Mintz A, Gibo D, Debinski W. Abstract 1218: Investigation of the mechanism and form of ephrinA1 released from cancer cells Cancer Research. 71: 1218-1218. DOI: 10.1158/1538-7445.Am2011-1218  0.759
2011 Nguyen V, Conyers JM, Zhu D, Hantgan R, Larson SM, Debinski W, Mintz A. Abstract B112: Personalizing anti-IL13R 2 therapy with real-time immunoPET visualization of biomarker expression. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B112  0.437
2010 Debinski W, Tatter SB. Convection-enhanced delivery to achieve widespread distribution of viral vectors: Predicting clinical implementation. Current Opinion in Molecular Therapeutics. 12: 647-53. PMID 21154156  0.499
2010 Candolfi M, Xiong W, Yagiz K, Liu C, Muhammad AK, Puntel M, Foulad D, Zadmehr A, Ahlzadeh GE, Kroeger KM, Tesarfreund M, Lee S, Debinski W, Sareen D, Svendsen CN, et al. Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proceedings of the National Academy of Sciences of the United States of America. 107: 20021-6. PMID 21030678 DOI: 10.1073/Pnas.1008261107  0.414
2010 Pandya H, Gibo DM, Debinski W. Molecular targeting of intracellular compartments specifically in cancer cells. Genes & Cancer. 1: 421-33. PMID 20740056 DOI: 10.1177/1947601910375274  0.63
2010 Nguyen V, Hollingsworth C, Debinski W, Mintz A. Abstract 5525: Targeting the IL13Rα2 tumor-restricted biomarker with a novel ligand delivery system Cancer Research. 70: 5525-5525. DOI: 10.1158/1538-7445.Am10-5525  0.351
2010 Pandya H, Gibo D, Debinski W. Abstract 5519: Development of ‘multiple-specificity’ vectors for targeted delivery to intracellular organelles of the glioblastoma multiforme tumor cells Cancer Research. 70: 5519-5519. DOI: 10.1158/1538-7445.Am10-5519  0.633
2010 Tome CML, Palma E, Wykoski J, Debinski W. Abstract 5465: Functional and structural characterization of the high-affinity EphA2-binding site of ephrinA1 Cancer Research. 70: 5465-5465. DOI: 10.1158/1538-7445.Am10-5465  0.413
2010 Calipari ES, Tallant EA, Lesser G, Debinski W, Gallagher PE. Abstract 3575: Angiotensin-(1-7) and temozolomide provide combinatorial inhibition of glioblastoma cell growth Cancer Research. 70: 3575-3575. DOI: 10.1158/1538-7445.Am10-3575  0.395
2009 Debinski W, Tatter SB. Convection-enhanced delivery for the treatment of brain tumors. Expert Review of Neurotherapeutics. 9: 1519-27. PMID 19831841 DOI: 10.1586/Ern.09.99  0.555
2009 Liu TF, Cai J, Gibo DM, Debinski W. Reoxygenation of hypoxic glioblastoma multiforme cells potentiates the killing effect of an interleukin-13-based cytotoxin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 160-8. PMID 19118043 DOI: 10.1158/1078-0432.Ccr-08-2151  0.398
2008 Chen J, Zhuang G, Frieden L, Debinski W. Eph receptors and Ephrins in cancer: common themes and controversies. Cancer Research. 68: 10031-3. PMID 19074866 DOI: 10.1158/0008-5472.Can-08-3010  0.345
2008 Wykosky J, Debinski W. The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting. Molecular Cancer Research : McR. 6: 1795-806. PMID 19074825 DOI: 10.1158/1541-7786.Mcr-08-0244  0.409
2008 Mintz A, Gibo DM, Madhankumar AB, Cladel NM, Christensen ND, Debinski W. Protein- and DNA-based active immunotherapy targeting interleukin-13 receptor alpha2. Cancer Biotherapy & Radiopharmaceuticals. 23: 581-9. PMID 18976118 DOI: 10.1089/Cbr.2008.0462  0.36
2008 Wykosky J, Palma E, Gibo DM, Ringler S, Turner CP, Debinski W. Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor Oncogene. 27: 7260-7273. PMID 18794797 DOI: 10.1038/Onc.2008.328  0.382
2008 Wykosky J, Gibo DM, Stanton C, Debinski W. Interleukin-13 receptor alpha 2, EphA2, and Fos-related antigen 1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 199-208. PMID 18172271 DOI: 10.1158/1078-0432.Ccr-07-1990  0.338
2008 Debinski W. Molecular targeting with recombinant cytotoxins for the treatment of brain tumors Drug Development Research. 69: 407-414. DOI: 10.1002/Ddr.20272  0.393
2007 Wykosky J, Gibo DM, Debinski W. A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells. Molecular Cancer Therapeutics. 6: 3208-18. PMID 18089715 DOI: 10.1158/1535-7163.Mct-07-0200  0.426
2006 Debinski W. Naturally occurring, unmodified bacterial toxin for the treatment of glioblastoma multiforme? Cancer Biology & Therapy. 5: 1569-70. PMID 17204857 DOI: 10.4161/Cbt.5.11.3656  0.324
2005 Couture D, Wykosky J, Gibo DM, Debinski W. 866 EphA2 Receptor Represents a New Marker and Therapeutic Target in Pediatric Malignancies. Neurosurgery. 57: 418-419. PMID 28184793 DOI: 10.1093/Neurosurgery/57.2.418C  0.329
2005 Wykosky J, Gibo DM, Stanton C, Debinski W. EphA2 as a novel molecular marker and target in glioblastoma multiforme. Molecular Cancer Research : McR. 3: 541-51. PMID 16254188 DOI: 10.1158/1541-7786.Mcr-05-0056  0.41
2005 Debinski W, Gibo DM. Fos-related antigen 1 modulates malignant features of glioma cells. Molecular Cancer Research : McR. 3: 237-49. PMID 15831677 DOI: 10.1158/1541-7786.Mcr-05-0004  0.377
2004 Madhankumar AB, Mintz A, Debinski W. Interleukin 13 mutants of enhanced avidity toward the glioma-associated receptor, IL13Ralpha2. Neoplasia (New York, N.Y.). 6: 15-22. PMID 15068667 DOI: 10.1016/S1476-5586(04)80049-6  0.32
2003 Mintz A, Gibo DM, Madhankumar AB, Debinski W. Molecular targeting with recombinant cytotoxins of interleukin-13 receptor alpha2-expressing glioma. Journal of Neuro-Oncology. 64: 117-23. PMID 12952292 DOI: 10.1007/Bf02700026  0.323
2003 Debinski W, Gibo D, Mintz A. Epigenetics in high-grade astrocytomas: opportunities for prevention and detection of brain tumors. Annals of the New York Academy of Sciences. 983: 232-42. PMID 12724228 DOI: 10.1111/J.1749-6632.2003.Tb05978.X  0.402
2002 Zhou G, Ye GJ, Debinski W, Roizman B. Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction. Proceedings of the National Academy of Sciences of the United States of America. 99: 15124-9. PMID 12417744 DOI: 10.1073/Pnas.232588699  0.349
2002 Debinski W. Local treatment of brain tumors with targeted chimera cytotoxic proteins. Cancer Investigation. 20: 801-9. PMID 12197239 DOI: 10.1081/Cnv-120003545  0.367
2002 Mintz A, Gibo DM, Slagle-Webb B, Christensen ND, Debinski W. IL-13Ralpha2 is a glioma-restricted receptor for interleukin-13. Neoplasia (New York, N.Y.). 4: 388-99. PMID 12192597 DOI: 10.1038/Sj.Neo.7900234  0.332
2002 Madhankumar AB, Mintz A, Debinski W. Alanine-scanning mutagenesis of alpha-helix D segment of interleukin-13 reveals new functionally important residues of the cytokine. The Journal of Biological Chemistry. 277: 43194-205. PMID 12189139 DOI: 10.1074/Jbc.M205047200  0.321
2001 Debinski W, Slagle-Webb B, Achen MG, Stacker SA, Tulchinsky E, Gillespie GY, Gibo DM. VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme. Molecular Medicine (Cambridge, Mass.). 7: 598-608. PMID 11778649 DOI: 10.1007/Bf03401866  0.32
2001 Nash KT, Thompson JP, Debinski W. Molecular targeting of malignant gliomas with novel multiply-mutated interleukin 13-based cytotoxins Critical Reviews in Oncology/Hematology. 39: 87-98. PMID 11418305 DOI: 10.1016/S1040-8428(01)00124-X  0.319
2000 Debinski W, Slagle B, Gibo DM, Powers SK, Gillespie GY. Expression of a restrictive receptor for interleukin 13 is associated with glial transformation. Journal of Neuro-Oncology. 48: 103-11. PMID 11083073 DOI: 10.1023/A:1006446426611  0.384
2000 Debinski W, Gibo DM. Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen Molecular Medicine (Cambridge, Mass.). 6: 440-449. PMID 10952023 DOI: 10.1007/Bf03401786  0.344
2000 Mintz A, Debinski W. Cancer genetics/epigenetics and the X chromosome: Possible new links for malignant glioma pathogenesis and immune-based therapies Critical Reviews in Oncogenesis. 11: 77-95. PMID 10795628 DOI: 10.1615/Critrevoncog.V11.I1.40  0.372
1999 Debinski W. Recombinant cytotoxins specific for cancer cells Annals of the New York Academy of Sciences. 886: 297-299. PMID 10667244 DOI: 10.1111/J.1749-6632.1999.Tb09441.X  0.327
1999 Thompson JP, Debinski W. Mutants of interleukin 13 with altered reactivity toward interleukin 13 receptors Journal of Biological Chemistry. 274: 29944-29950. PMID 10514477 DOI: 10.1074/Jbc.274.42.29944  0.345
1999 Debinski W, Gibo DM, Slagle B, Powers SK, Gillespie GY. Receptor for interleukin 13 is abundantly and specifically over-expressed in patients with glioblastoma multiforme International Journal of Oncology. 15: 481-486. PMID 10427128 DOI: 10.3892/Ijo.15.3.481  0.377
1999 Debinski W, Gibo DM, Hulet SW, Connor JR, Gillespie GY. Receptor for interleukin 13 is a marker and therapeutic target for human high-grade gliomas Clinical Cancer Research. 5: 985-990. PMID 10353730  0.301
1998 Debinski W, Gibo DM, Obiri NI, Kealiher A, Puri RK. Novel anti-brain tumor cytotoxins specific for cancer cells Nature Biotechnology. 16: 449-453. PMID 9592393 DOI: 10.1038/Nbt0598-449  0.407
1998 Debinski W, Gibo DM, Puri RK. Novel way to increase targeting specificity to a human gliblastoma- associated receptor for interleukin 13 International Journal of Cancer. 76: 547-551. PMID 9590132 DOI: 10.1002/(Sici)1097-0215(19980518)76:4<547::Aid-Ijc17>3.0.Co;2-4  0.376
1997 Maini A, Hillman G, Haas GP, Wang CY, Montecillo E, Hamzavi F, Edson Pontes J, Leland P, Pastan I, Debinski W, Puri RK. Interleukin-13 receptors on human prostate carcinoma cell lines represent a novel target for a chimeric protein composed of IL-13 and a mutated form of pseudomonas exotoxin Journal of Urology. 158: 948-953. PMID 9258124 DOI: 10.1016/S0022-5347(01)64369-6  0.371
1995 Debinski W, Obiri NI, Powers SK, Pastan I, Puri RK. Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 1: 1253-8. PMID 9815919  0.304
1994 Debinski W, Puri RK, Pastan I. Interleukin-4 receptors expressed on tumor cells may serve as a target for anticancer therapy using chimeric Pseudomonas exotoxin International Journal of Cancer. 58: 744-748. PMID 8077061 DOI: 10.1002/Ijc.2910580520  0.313
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