| Year |
Citation |
Score |
| 2023 |
Meng Q, Zhu R, Mao Y, Zhu S, Wu Y, Huang LSM, Ciechanover A, An J, Xu Y, Huang Z. Biological and mutational analyses of CXCR4-antagonist interactions and design of new antagonistic analogs. Bioscience Reports. 43. PMID 38131305 DOI: 10.1042/BSR20230981 |
0.334 |
|
| 2023 |
Zhu R, Sang X, Zhou J, Meng Q, Huang LSM, Xu Y, An J, Huang Z. CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120. Viruses. 15. PMID 37243169 DOI: 10.3390/v15051084 |
0.344 |
|
| 2022 |
Zhu R, Meng Q, Zhang H, Zhang G, Huang LSM, Xu Y, Schooley RT, An J, Huang Z. IV-1 gp120-CXCR4 recognition probed with synthetic nanomolar affinity D-peptides containing fragments of gp120 V3 loop. European Journal of Medicinal Chemistry. 244: 114797. PMID 36270088 DOI: 10.1016/j.ejmech.2022.114797 |
0.376 |
|
| 2022 |
Fan T, Liang B, Nie L, Wang J, Zhang H, Ciechanover A, Xu Y, An J, Huang Z. A synthetic bivalent peptide ligand of EphB4 with potent agonistic activity. European Journal of Medicinal Chemistry. 244: 114804. PMID 36208510 DOI: 10.1016/j.ejmech.2022.114804 |
0.345 |
|
| 2022 |
Fang X, Meng Q, Zhang H, Fang X, Huang LS, Zhang X, Schooley RT, Ciechanover A, An J, Xu Y, Huang Z. A fragment integrational approach to GPCR inhibition: Identification of a high affinity small molecule CXCR4 antagonist. European Journal of Medicinal Chemistry. 231: 114150. PMID 35124530 DOI: 10.1016/j.ejmech.2022.114150 |
0.389 |
|
| 2020 |
Fang X, Meng Q, Zhang H, Liang B, Zhu S, Wang J, Zhang C, Huang LS, Zhang X, Schooley RT, An J, Xu Y, Huang Z. Design, synthesis, and biological characterization of a new class of symmetrical polyamine-based small molecule CXCR4 antagonists. European Journal of Medicinal Chemistry. 200: 112410. PMID 32492596 DOI: 10.1016/J.Ejmech.2020.112410 |
0.384 |
|
| 2020 |
Zhang C, Zhu R, Cao Q, Yang X, Huang Z, An J. Discoveries and developments of CXCR4-targeted HIV-1 entry inhibitors. Experimental Biology and Medicine (Maywood, N.J.). 1535370220901498. PMID 32019336 DOI: 10.1177/1535370220901498 |
0.425 |
|
| 2019 |
Zhu S, Meng Q, Schooley RT, An J, Xu Y, Huang Z. Structural and Biological Characterizations of Novel High-Affinity Fluorescent Probes with Overlapped and Distinctive Binding Regions on CXCR4. Molecules (Basel, Switzerland). 24. PMID 31412600 DOI: 10.3390/Molecules24162928 |
0.366 |
|
| 2019 |
Yang S, Mao Y, Zhang H, Xu Y, An J, Huang Z. The chemical biology of apoptosis: Revisited after 17 years. European Journal of Medicinal Chemistry. 177: 63-75. PMID 31129454 DOI: 10.1016/J.Ejmech.2019.05.019 |
0.357 |
|
| 2019 |
Zhang C, Huang LS, Zhu R, Meng Q, Zhu S, Xu Y, Zhang H, Fang X, Zhang X, Zhou J, Schooley RT, Yang X, Huang Z, An J. High affinity CXCR4 inhibitors generated by linking low affinity peptides. European Journal of Medicinal Chemistry. 172: 174-185. PMID 30978562 DOI: 10.1016/J.Ejmech.2019.03.056 |
0.477 |
|
| 2018 |
Zhang C, Zhang H, Huang LS, Zhu S, Xu Y, Zhang XQ, Schooley RT, Yang X, Huang Z, An J. Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor. Molecules (Basel, Switzerland). 23. PMID 30463393 DOI: 10.3390/Molecules23113036 |
0.44 |
|
| 2018 |
Zhang H, Fang X, Meng Q, Mao Y, Xu Y, Fan T, An J, Huang Z. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. European Journal of Medicinal Chemistry. 157: 380-396. PMID 30099258 DOI: 10.1016/J.Ejmech.2018.07.043 |
0.32 |
|
| 2018 |
Mao Y, Meng Q, Song P, Zhu S, Xu Y, Snyder EY, An J, Huang Z. Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice. Cell Transplantation. 963689718784957. PMID 29991278 DOI: 10.1177/0963689718784957 |
0.429 |
|
| 2016 |
Yang Y, Gao M, Zhang Q, Zhang C, Yang X, Huang Z, An J. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorganic & Medicinal Chemistry. PMID 27658790 DOI: 10.1016/J.Bmc.2016.08.062 |
0.444 |
|
| 2014 |
Yang Y, Zhang Q, Gao M, Yang X, Huang Z, An J. A novel CXCR4-selective high-affinity fluorescent probe and its application in competitive binding assays. Biochemistry. 53: 4881-3. PMID 25058910 DOI: 10.1021/Bi500500H |
0.356 |
|
| 2013 |
Han X, Xu Y, Yang Y, Xi J, Tian W, Duggineni S, Huang Z, An J. Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity. Plos One. 8: e80183. PMID 24265799 DOI: 10.1371/Journal.Pone.0080183 |
0.459 |
|
| 2013 |
Duggineni S, Mitra S, Lamberto I, Han X, Xu Y, An J, Pasquale EB, Huang Z. Design and Synthesis of Potent Bivalent Peptide Agonists Targeting the EphA2 Receptor. Acs Medicinal Chemistry Letters. 4. PMID 24167659 DOI: 10.1021/Ml3004523 |
0.449 |
|
| 2013 |
Xu Y, Duggineni S, Espitia S, Richman DD, An J, Huang Z. A synthetic bivalent ligand of CXCR4 inhibits HIV infection. Biochemical and Biophysical Research Communications. 435: 646-50. PMID 23688427 DOI: 10.1016/J.Bbrc.2013.05.038 |
0.513 |
|
| 2013 |
Xi J, Zhu X, Feng Y, Huang N, Luo G, Mao Y, Han X, Tian W, Wang G, Han X, Luo R, Huang Z, An J. Development of a novel class of tubulin inhibitors with promising anticancer activities. Molecular Cancer Research : McR. 11: 856-64. PMID 23666368 DOI: 10.1158/1541-7786.Mcr-12-0177 |
0.337 |
|
| 2013 |
Duggineni S, Mitra S, Noberini R, Han X, Lin N, Xu Y, Tian W, An J, Pasquale EB, Huang Z. Design, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4. Biochemical Pharmacology. 85: 507-13. PMID 23253822 DOI: 10.1016/J.Bcp.2012.12.005 |
0.441 |
|
| 2012 |
Choi WT, Kumar S, Madani N, Han X, Tian S, Dong CZ, Liu D, Duggineni S, Yuan J, Sodroski JG, Huang Z, An J. A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry. Biochemistry. 51: 7078-86. PMID 22897429 DOI: 10.1021/Bi2016712 |
0.725 |
|
| 2012 |
Dong CZ, Tian S, Choi WT, Kumar S, Liu D, Xu Y, Han X, Huang Z, An J. Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1α probed by novel N-methylated synthetically and modularly modified chemokine analogues. Biochemistry. 51: 5951-7. PMID 22779681 DOI: 10.1021/Bi3003742 |
0.68 |
|
| 2012 |
Mao Y, Lin N, Tian W, Han X, Han X, Huang Z, An J. Design, synthesis, and biological evaluation of new diaminoquinazolines as β-catenin/Tcf4 pathway inhibitors. Journal of Medicinal Chemistry. 55: 1346-59. PMID 22229647 DOI: 10.1021/Jm201494A |
0.322 |
|
| 2012 |
Tian W, Han X, Yan M, Xu Y, Duggineni S, Lin N, Luo G, Li YM, Han X, Huang Z, An J. Structure-based discovery of a novel inhibitor targeting the β-catenin/Tcf4 interaction. Biochemistry. 51: 724-31. PMID 22224445 DOI: 10.1021/Bi201428H |
0.313 |
|
| 2012 |
Choi WT, Duggineni S, Xu Y, Huang Z, An J. Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4). Journal of Medicinal Chemistry. 55: 977-94. PMID 22085380 DOI: 10.1021/Jm200568C |
0.69 |
|
| 2011 |
Noberini R, Mitra S, Salvucci O, Valencia F, Duggineni S, Prigozhina N, Wei K, Tosato G, Huang Z, Pasquale EB. PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity. Plos One. 6: e28611. PMID 22194865 DOI: 10.1371/Journal.Pone.0028611 |
0.417 |
|
| 2011 |
Dong CZ, Tian S, Madani N, Choi WT, Kumar S, Liu D, Sodroski JG, Huang Z, An J. Role of CXCR4 internalization in the anti-HIV activity of stromal cell-derived factor-1α probed by a novel synthetically and modularly modified-chemokine analog. Experimental Biology and Medicine (Maywood, N.J.). 236: 1413-9. PMID 22101518 DOI: 10.1258/Ebm.2011.011260 |
0.703 |
|
| 2011 |
Kawatkar SP, Yan M, Gevariya H, Lim MY, Eisold S, Zhu X, Huang Z, An J. Computational analysis of the structural mechanism of inhibition of chemokine receptor CXCR4 by small molecule antagonists. Experimental Biology and Medicine (Maywood, N.J.). 236: 844-50. PMID 21697335 DOI: 10.1258/Ebm.2011.010345 |
0.428 |
|
| 2011 |
Hu Q, Nie A, Welsh K, Pinacho Crisóstomo FR, Zhu X, Li Z, An J, Reed JC, Zhang L, Huang Z. Novel X-linked inhibitor of apoptosis protein inhibitors as probes of apoptosis in biology and medicine. Experimental Biology and Medicine (Maywood, N.J.). 236: 247-51. PMID 21321323 DOI: 10.1258/Ebm.2010.010284 |
0.409 |
|
| 2011 |
Garrison JB, Correa RG, Gerlic M, Yip KW, Krieg A, Tamble CM, Shi R, Welsh K, Duggineni S, Huang Z, Ren K, Du C, Reed JC. ARTS and Siah collaborate in a pathway for XIAP degradation. Molecular Cell. 41: 107-16. PMID 21185211 DOI: 10.1016/J.Molcel.2010.12.002 |
0.368 |
|
| 2010 |
Mitra S, Duggineni S, Koolpe M, Zhu X, Huang Z, Pasquale EB. Structure-activity relationship analysis of peptides targeting the EphA2 receptor. Biochemistry. 49: 6687-95. PMID 20677833 DOI: 10.1021/Bi1006223 |
0.446 |
|
| 2010 |
Carter B, Mak DH, Schober WD, Konopleva M, Cortes JE, Kantarjian HM, Koller E, Huang Z, Reed JC, Andreeff M. Targeting XIAP and ARC (apoptosis repressor with caspase recruitment domain) Overcomes Imatinib Resitance In Blast Crisis CML Cells. Blood. 116: 3415-3415. DOI: 10.1182/Blood.V116.21.3415.3415 |
0.327 |
|
| 2009 |
Crisóstomo FR, Feng Y, Zhu X, Welsh K, An J, Reed JC, Huang Z. Design and synthesis of a simplified inhibitor for XIAP-BIR3 domain. Bioorganic & Medicinal Chemistry Letters. 19: 6413-8. PMID 19819692 DOI: 10.1016/J.Bmcl.2009.09.058 |
0.363 |
|
| 2009 |
Krieg A, Correa RG, Garrison JB, Le Negrate G, Welsh K, Huang Z, Knoefel WT, Reed JC. XIAP mediates NOD signaling via interaction with RIP2. Proceedings of the National Academy of Sciences of the United States of America. 106: 14524-9. PMID 19667203 DOI: 10.1073/Pnas.0907131106 |
0.381 |
|
| 2009 |
Wu D, Pang Y, Ke Y, Yu J, He Z, Tautz L, Mustelin T, Ding S, Huang Z, Feng GS. A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. Plos One. 4: e4914. PMID 19290061 DOI: 10.1371/Journal.Pone.0004914 |
0.311 |
|
| 2009 |
Mitra S, Duggineni S, Koolpe M, Dail M, Zhu X, Huang Z, Pasquale EB. Abstract B201: Selective peptides for targeting EphA2 in cancer cells Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B201 |
0.399 |
|
| 2008 |
Zhai D, Jin C, Huang Z, Satterthwait AC, Reed JC. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. The Journal of Biological Chemistry. 283: 9580-6. PMID 18178565 DOI: 10.1074/Jbc.M708426200 |
0.328 |
|
| 2008 |
Drag M, Mikolajczyk J, Krishnakumar IM, Huang Z, Salvesen GS. Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family. The Biochemical Journal. 409: 461-9. PMID 17916063 DOI: 10.1042/Bj20070940 |
0.33 |
|
| 2007 |
Liu D, Madani N, Li Y, Cao R, Choi WT, Kawatkar SP, Lim MY, Kumar S, Dong CZ, Wang J, Russell JD, Lefebure CR, An J, Wilson S, Gao YG, ... ... Huang Z, et al. Crystal structure and structural mechanism of a novel anti-human immunodeficiency virus and D-amino acid-containing chemokine. Journal of Virology. 81: 11489-98. PMID 17686848 DOI: 10.1128/Jvi.02845-06 |
0.704 |
|
| 2007 |
Li Y, Liu D, Cao R, Kumar S, Dong C, An J, Wilson SR, Gao YG, Huang Z. Crystal structure of chemically synthesized vMIP-II. Proteins. 67: 243-6. PMID 17243149 DOI: 10.1002/Prot.21172 |
0.451 |
|
| 2007 |
Choi WT, Kaul M, Kumar S, Wang J, Kumar IM, Dong CZ, An J, Lipton SA, Huang Z. Neuronal apoptotic signaling pathways probed and intervened by synthetically and modularly modified (SMM) chemokines. The Journal of Biological Chemistry. 282: 7154-63. PMID 17218311 DOI: 10.1074/Jbc.M611599200 |
0.688 |
|
| 2007 |
An J, Chervin AS, Nie A, Ducoff HS, Huang Z. Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. Oncogene. 26: 652-61. PMID 16909121 DOI: 10.1038/Sj.Onc.1209830 |
0.303 |
|
| 2006 |
Zeng Z, Samudio IJ, Munsell M, An J, Huang Z, Estey E, Andreeff M, Konopleva M. Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias. Molecular Cancer Therapeutics. 5: 3113-21. PMID 17172414 DOI: 10.1158/1535-7163.Mct-06-0228 |
0.415 |
|
| 2006 |
Wang J, Kumar S, Choi WT, Dong C, Huang Z. Design and synthesis of novel chemokine analogs derived from vMIP-II. Protein and Peptide Letters. 13: 499-501. PMID 16800805 DOI: 10.2174/092986606776819574 |
0.662 |
|
| 2006 |
Ghosh S, Nie A, An J, Huang Z. Structure-based virtual screening of chemical libraries for drug discovery. Current Opinion in Chemical Biology. 10: 194-202. PMID 16675286 DOI: 10.1016/J.Cbpa.2006.04.002 |
0.324 |
|
| 2006 |
Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, ... Huang Z, et al. SMM-chemokines: A class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development Chemistry and Biology. 13: 69-79. PMID 16426973 DOI: 10.1016/J.Chembiol.2005.10.012 |
0.702 |
|
| 2006 |
Shiryaev SA, Ratnikov BI, Chekanov AV, Sikora S, Rozanov DV, Godzik A, Wang J, Smith JW, Huang Z, Lindberg I, Samuel MA, Diamond MS, Strongin AY. Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. The Biochemical Journal. 393: 503-11. PMID 16229682 DOI: 10.1042/Bj20051374 |
0.37 |
|
| 2005 |
Dong CZ, Kumar S, Choi WT, Madani N, Tian S, An J, Sodroski JG, Huang Z. Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand. Journal of Medicinal Chemistry. 48: 7923-4. PMID 16335916 DOI: 10.1021/Jm050829U |
0.714 |
|
| 2005 |
Choi WT, Tian S, Dong CZ, Kumar S, Liu D, Madani N, An J, Sodroski JG, Huang Z. Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. Journal of Virology. 79: 15398-404. PMID 16306611 DOI: 10.1128/Jvi.79.24.15398-15404.2005 |
0.71 |
|
| 2005 |
Tian S, Choi WT, Liu D, Pesavento J, Wang Y, An J, Sodroski JG, Huang Z. Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1α on CXCR4 transmembrane helical domains Journal of Virology. 79: 12667-12673. PMID 16188969 DOI: 10.1128/Jvi.79.20.12667-12673.2005 |
0.69 |
|
| 2005 |
Liu D, Yang B, Cao R, Huang Z. A chemical strategy to promote helical peptide-protein interactions involved in apoptosis. Bioorganic & Medicinal Chemistry Letters. 15: 4467-9. PMID 16137879 DOI: 10.1016/J.Bmcl.2005.07.031 |
0.372 |
|
| 2005 |
Mori M, Liu D, Kumar S, Huang Z. NMR structures of anti-HIV D-peptides derived from the N-terminus of viral chemokine vMIP-II. Biochemical and Biophysical Research Communications. 335: 651-8. PMID 16115468 DOI: 10.1016/J.Bbrc.2005.07.137 |
0.459 |
|
| 2004 |
Khan MZ, Brandimarti R, Patel JP, Huynh N, Wang J, Huang Z, Fatatis A, Meucci O. Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. Aids Research and Human Retroviruses. 20: 1063-71. PMID 15585097 DOI: 10.1089/Aid.2004.20.1063 |
0.415 |
|
| 2004 |
Yang B, Liu D, Huang Z. Synthesis and helical structure of lactam bridged BH3 peptides derived from pro-apoptotic Bcl-2 family proteins. Bioorganic & Medicinal Chemistry Letters. 14: 1403-6. PMID 15006371 DOI: 10.1016/J.Bmcl.2003.09.101 |
0.372 |
|
| 2004 |
Huang Z, Liu D, Madani N, Kumar S, Choi W, Cao R, Li Y, Gao Y, Dong C, Wang J, An J, Sodroski JG. A Novel Synthetic Chemokine Containing D-Amino Acids That Binds to the CXCR4 Receptor and Inhibits HIV-1 Infection. Blood. 104: 603-603. DOI: 10.1182/Blood.V104.11.603.603 |
0.689 |
|
| 2004 |
Huang Z, Kumar S, Choi W, Madani N, Dong C, Liu D, Wang J, An J, Sodroski JG. A New Class of Chemokine Analogs as Useful Research Tools to Study Chemokine Receptor Function and Promising Therapeutic Agents. Blood. 104: 3839-3839. DOI: 10.1182/Blood.V104.11.3839.3839 |
0.698 |
|
| 2002 |
Huang Z. The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules. Chemistry & Biology. 9: 1059-72. PMID 12401491 DOI: 10.1016/S1074-5521(02)00247-8 |
0.345 |
|
| 2002 |
Huang Z. Structure, function and modulation of chemokine receptors: members of the g-protein-coupled receptor superfamily. Mini Reviews in Medicinal Chemistry. 2: 373-83. PMID 12370058 |
0.376 |
|
| 2002 |
Milella M, Estrov Z, Kornblau SM, Carter BZ, Konopleva M, Tari A, Schober WD, Harris D, Leysath CE, Lopez-Berestein G, Huang Z, Andreeff M. Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia. Blood. 99: 3461-4. PMID 11964319 DOI: 10.1182/Blood.V99.9.3461 |
0.314 |
|
| 2002 |
Zhou N, Luo Z, Luo J, Fan X, Cayabyab M, Hiraoka M, Liu D, Han X, Pesavento J, Dong CZ, Wang Y, An J, Kaji H, Sodroski JG, Huang Z. Exploring the stereochemistry of CXCR4-peptide recognition and inhibiting HIV-1 entry with D-peptides derived from chemokines Journal of Biological Chemistry. 277: 17476-17485. PMID 11880384 DOI: 10.1074/Jbc.M202063200 |
0.475 |
|
| 2001 |
Zhou N, Luo Z, Luo J, Liu D, Hall JW, Pomerantz RJ, Huang Z. Structural and Functional Characterization of Human CXCR4 as a Chemokine Receptor and HIV-1 Co-receptor by Mutagenesis and Molecular Modeling Studies Journal of Biological Chemistry. 276: 42826-42833. PMID 11551942 DOI: 10.1074/Jbc.M106582200 |
0.524 |
|
| 2000 |
Huang Z. Bcl-2 family proteins as targets for anticancer drug design Oncogene. 19: 6627-6631. PMID 11426648 DOI: 10.1038/Sj.Onc.1204087 |
0.333 |
|
| 2000 |
Luo Z, Fan X, Zhou N, Hiraoka M, Luo J, Kaji H, Huang Z. Structure-function study and anti-HIV activity of synthetic peptide analogues derived from viral chemokine vMIP-II. Biochemistry. 39: 13545-50. PMID 11063591 DOI: 10.1021/Bi000633Q |
0.477 |
|
| 2000 |
Srinivasula SM, Datta P, Fan XJ, Fernandes-Alnemri T, Huang Z, Alnemri ES. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. The Journal of Biological Chemistry. 275: 36152-7. PMID 10950947 DOI: 10.1074/Jbc.C000533200 |
0.337 |
|
| 2000 |
Wang JL, Liu D, Zhang ZJ, Shan S, Han X, Srinivasula SM, Croce CM, Alnemri ES, Huang Z. Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7124-9. PMID 10860979 DOI: 10.1073/Pnas.97.13.7124 |
0.381 |
|
| 2000 |
Zhou N, Luo Z, Luo J, Hall JW, Huang Z. A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II Biochemistry. 39: 3782-3787. PMID 10736178 DOI: 10.1021/Bi992750V |
0.495 |
|
| 2000 |
Sarmiento M, Wu L, Keng YF, Song L, Luo Z, Huang Z, Wu GZ, Yuan AK, Zhang ZY. Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B. Journal of Medicinal Chemistry. 43: 146-55. PMID 10649970 DOI: 10.1021/Jm990329Z |
0.372 |
|
| 2000 |
Zhou N, Luo Z, Hall JW, Luo J, Han X, Huang Z. Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction European Journal of Immunology. 30: 164-173. PMID 10602038 DOI: 10.1002/1521-4141(200001)30:1<164::Aid-Immu164>3.0.Co;2-X |
0.499 |
|
| 2000 |
Yu N, Aramini JM, Germann MW, Huang Z. Reactions of salicylaldehydes with alkyl cyanoacetates on the surface of solid catalysts: Syntheses of 4H-chromene derivatives Tetrahedron Letters. 41: 6993-6996. DOI: 10.1016/S0040-4039(00)01195-3 |
0.309 |
|
| 1999 |
Butcher DJ, Luo Z, Huang Z. The Roles Of Side Chain And Backbone In Protein Structure Probed With Glycine- And Sarcosine-Rich Synthetic Leucine Zipper Peptides Biochemical and Biophysical Research Communications. 265: 350-355. PMID 10558870 DOI: 10.1006/Bbrc.1999.1687 |
0.361 |
|
| 1999 |
Luo J, Luo Z, Zhou N, Hall JW, Huang Z. Attachment of C-terminus of SDF-1 enhances the biological activity of its N-terminal peptide Biochemical and Biophysical Research Communications. 264: 42-47. PMID 10527838 DOI: 10.1006/Bbrc.1999.1476 |
0.401 |
|
| 1999 |
Luo Z, Zhou N, Luo J, Hall JW, Huang Z. The role of positively charged residues in CXCR4 recognition probed with synthetic peptides Biochemical and Biophysical Research Communications. 263: 691-695. PMID 10512741 DOI: 10.1006/Bbrc.1999.1441 |
0.402 |
|
| 1999 |
Reiss K, Yumet G, Shan S, Huang Z, Alnemri E, Srinivasula SM, Wang JY, Morrione A, Baserga R. Synthetic peptide sequence from the C-terminus of the insulin-like growth factor-I receptor that induces apoptosis and inhibition of tumor growth. Journal of Cellular Physiology. 181: 124-35. PMID 10457360 DOI: 10.1002/(Sici)1097-4652(199910)181:1<124::Aid-Jcp13>3.0.Co;2-0 |
0.365 |
|
| 1999 |
Rubini M, D'Ambrosio C, Carturan S, Yumet G, Catalano E, Shan S, Huang Z, Criscuolo M, Pifferi M, Baserga R. Characterization Of An Antibody That Can Detect An Activated Igf-I Receptor In Human Cancers Experimental Cell Research. 251: 22-32. PMID 10438568 DOI: 10.1006/Excr.1999.4562 |
0.317 |
|
| 1999 |
Marcinkiewicz C, Calvete JJ, Marcinkiewicz MM, Raida M, Vijay-Kumar S, Huang Z, Lobb RR, Niewiarowski S. EC3, a Novel Heterodimeric Disintegrin from Echis carinatus Venom, Inhibits α4 and α5 Integrins in an RGD-independent Manner Journal of Biological Chemistry. 274: 12468-12473. PMID 10212222 DOI: 10.1074/Jbc.274.18.12468 |
0.334 |
|
| 1998 |
Li S, Choksi S, Shan S, Hu X, Gao J, Korngold R, Huang Z. Identification of the CD8 DE loop as a surface functional epitope. Implications for major histocompatibility complex class I binding and CD8 inhibitor design. The Journal of Biological Chemistry. 273: 16442-5. PMID 9632710 DOI: 10.1074/Jbc.273.26.16442 |
0.352 |
|
| 1998 |
Luo Z, Butcher DJ, Murali R, Srinivasan A, Huang Z. Structural Studies of Synthetic Peptide Fragments Derived from the HIV-1 Vpr Protein Biochemical and Biophysical Research Communications. 244: 732-736. PMID 9535734 DOI: 10.1006/Bbrc.1998.8330 |
0.433 |
|
| 1997 |
Huang Z, Li S, Korngold R. Immunoglobulin superfamily proteins: Structure, mechanisms, and drug discovery Biopolymers. 43: 367-382. PMID 9566118 DOI: 10.1002/(Sici)1097-0282(1997)43:5<367::Aid-Bip3>3.0.Co;2-T |
0.369 |
|
| 1997 |
Resnicoff M, Huang Z, Herbert D, Abraham D, Baserga R. A Novel Class of Peptides That Induce Apoptosis and Abrogate Tumorigenesisin Vivo Biochemical and Biophysical Research Communications. 240: 208-212. PMID 9367911 DOI: 10.1006/Bbrc.1997.7640 |
0.339 |
|
| 1997 |
Butcher DJ, Kowalska MA, Li S, Luo Z, Shan S, Lu Z, Niewiarowski S, Huang Z. A natural motif approach to protein design: a synthetic leucine zipper peptide mimics the biological function of the platelet factor 4 protein. Febs Letters. 409: 183-7. PMID 9202142 DOI: 10.1016/S0014-5793(97)00504-8 |
0.384 |
|
| 1997 |
Satoh T, Aramini JM, Li S, Friedman TM, Gao J, Edling AE, Townsend R, Koch U, Choksi S, Germann MW, Korngold R, Huang Z. Bioactive peptide design based on protein surface epitopes. A cyclic heptapeptide mimics CD4 domain 1 CC' loop and inhibits CD4 biological function. The Journal of Biological Chemistry. 272: 12175-80. PMID 9115290 DOI: 10.1074/Jbc.272.18.12175 |
0.372 |
|
| 1997 |
Li S, Gao J, Satoh T, Friedman TM, Edling AE, Koch U, Choksi S, Han X, Korngold R, Huang Z. A computer screening approach to immunoglobulin superfamily structures and interactions: discovery of small non-peptidic CD4 inhibitors as novel immunotherapeutics. Proceedings of the National Academy of Sciences of the United States of America. 94: 73-8. PMID 8990163 DOI: 10.1073/Pnas.94.1.73 |
0.37 |
|
| 1996 |
Satoh T, Li S, Friedman TM, Wiaderkiewicz R, Korngold R, Huang Z. Synthetic peptides derived from the fourth domain of CD4 antagonize off function and inhibit T cell activation. Biochemical and Biophysical Research Communications. 224: 438-43. PMID 8702407 DOI: 10.1006/Bbrc.1996.1045 |
0.339 |
|
| 1994 |
Huang Z, Pröbstl A, Spencer JR, Yamazaki T, Goodman M. Cyclic hexapeptide analogs of somatostatin containing bridge modifications. Syntheses and conformational analyses. International Journal of Peptide and Protein Research. 42: 352-65. PMID 7902342 DOI: 10.1111/J.1399-3011.1993.Tb00505.X |
0.373 |
|
| Show low-probability matches. |