| Year |
Citation |
Score |
| 2021 |
Mohan V, Gaffney JP, Solomonov I, Levin M, Klepfish M, Akbareian S, Grünwald B, Dym O, Eisenstein M, Yu KH, Kelsen DP, Krüger A, Edwards DR, Sagi I. Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill. Cancers. 13. PMID 33918254 DOI: 10.3390/cancers13071679 |
0.379 |
|
| 2020 |
Lambert J, Makin K, Akbareian S, Johnson R, Alghamdi AAA, Robinson SD, Edwards DR. ADAMTS-1 and syndecan-4 intersect in the regulation of cell migration and angiogenesis. Journal of Cell Science. 133. PMID 32269093 DOI: 10.1242/Jcs.235762 |
0.493 |
|
| 2020 |
Lambert J, Edwards DR. Analysis of ADAMTS Effects on Cell Adhesion and Migration. Methods in Molecular Biology (Clifton, N.J.). 2043: 179-193. PMID 31463912 DOI: 10.1007/978-1-4939-9698-8_15 |
0.39 |
|
| 2019 |
Mattern J, Roghi CS, Hurtz M, Knäuper V, Edwards DR, Poghosyan Z. ADAM15 mediates upregulation of Claudin-1 expression in breast cancer cells. Scientific Reports. 9: 12540. PMID 31467400 DOI: 10.1038/S41598-019-49021-3 |
0.42 |
|
| 2018 |
Desanlis I, Felstead HL, Edwards DR, Wheeler GN. ADAMTS9, a member of the ADAMTS family, in Xenopus development. Gene Expression Patterns : Gep. PMID 29935379 DOI: 10.1016/J.Gep.2018.06.001 |
0.421 |
|
| 2018 |
Atkinson SJ, Gontarczyk AM, Alghamdi AA, Ellison TS, Johnson RT, Fowler WJ, Kirkup BM, Silva BC, Harry BE, Schneider JG, Weilbaecher KN, Mogensen MM, Bass MD, Parsons M, Edwards DR, et al. The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration. Embo Reports. PMID 29794156 DOI: 10.15252/Embr.201744578 |
0.317 |
|
| 2017 |
Sarper M, Allen MD, Gomm J, Haywood L, Decock J, Thirkettle S, Ustaoglu A, Sarker SJ, Marshall J, Edwards DR, Jones JL. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Research : Bcr. 19: 33. PMID 28330493 DOI: 10.1186/S13058-017-0822-9 |
0.497 |
|
| 2017 |
Piddock RE, Loughran N, Marlein CR, Robinson SD, Edwards DR, Yu S, Pillinger GE, Zhou Z, Zaitseva L, Auger MJ, Rushworth SA, Bowles KM. PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment. Blood Cancer Journal. 7: e539. PMID 28282033 DOI: 10.1038/Bcj.2017.16 |
0.342 |
|
| 2017 |
Rice T, Larsen JE, Li H, Nuttall RK, Larsen PH, Casha S, Hurlbert J, Edwards DR, Yong VW. Neuroprotection by minocycline in murine traumatic spinal cord injury: analyses of matrix metalloproteinases Neuroimmunology and Neuroinflammation. 4: 243. DOI: 10.20517/2347-8659.2017.51 |
0.348 |
|
| 2017 |
Shafat M, Oellerich T, Mohr S, Robinson S, Edwards D, Piddock R, Abdul-Aziz A, Marlein C, Fenech M, Turner J, Lawes M, Zaitseva L, Watkins J, Bowles K, Rushworth S. Abstract 4327: Bone marrow adipocytes drive transcriptional changes in leukemic blasts to enhance their capacity to derive energy from free fatty acid metabolism Cancer Research. 77: 4327-4327. DOI: 10.1158/1538-7445.Am2017-4327 |
0.305 |
|
| 2016 |
Grunwald B, Vandooren J, Gerg M, Ahomaa K, Hunger A, Berchtold S, Akbareian S, Schaten S, Knolle P, Edwards DR, Opdenakker G, Kruger A. Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow. Molecular Cancer Research : McR. PMID 27489361 DOI: 10.1158/1541-7786.Mcr-16-0180 |
0.525 |
|
| 2015 |
Ellison TS, Atkinson SJ, Steri V, Kirkup BM, Preedy ME, Johnson RT, Ruhrberg C, Edwards DR, Schneider JG, Weilbaecher K, Robinson SD. Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Disease Models & Mechanisms. 8: 1105-19. PMID 26159543 DOI: 10.1242/Dmm.019927 |
0.339 |
|
| 2015 |
Kelwick R, Desanlis I, Wheeler GN, Edwards DR. The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family. Genome Biology. 16: 113. PMID 26025392 DOI: 10.1186/S13059-015-0676-3 |
0.403 |
|
| 2015 |
Decock J, Hendrickx W, Thirkettle S, Gutiérrez-Fernández A, Robinson SD, Edwards DR. Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Research : Bcr. 17: 38. PMID 25848906 DOI: 10.1186/S13058-015-0545-8 |
0.458 |
|
| 2015 |
Kelwick R, Wagstaff L, Decock J, Roghi C, Cooley LS, Robinson SD, Arnold H, Gavrilović J, Jaworski DM, Yamamoto K, Nagase H, Seubert B, Krüger A, Edwards DR. Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15. International Journal of Cancer. Journal International Du Cancer. 136: E14-26. PMID 25099234 DOI: 10.1002/Ijc.29129 |
0.494 |
|
| 2014 |
Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, et al. Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 344-57. PMID 24150233 DOI: 10.1158/1078-0432.Ccr-13-1504 |
0.328 |
|
| 2014 |
Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards D, Fruttiger M, Hodivala-Dilke KM, Robinson SD. Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice. Circulation Research. 114: 79-91. PMID 24103390 DOI: 10.1161/Circresaha.114.301591 |
0.331 |
|
| 2013 |
Gerrard DT, Fricke C, Edward DA, Edwards DR, Chapman T. Genome-Wide Responses of Female Fruit Flies Subjected to Divergent Mating Regimes. Plos One. 8: e68136. PMID 23826372 DOI: 10.1371/Journal.Pone.0068136 |
0.307 |
|
| 2013 |
Thirkettle S, Decock J, Arnold H, Pennington CJ, Jaworski DM, Edwards DR. Matrix metalloproteinase 8 (collagenase 2) induces the expression of interleukins 6 and 8 in breast cancer cells. The Journal of Biological Chemistry. 288: 16282-94. PMID 23632023 DOI: 10.1074/Jbc.M113.464230 |
0.512 |
|
| 2013 |
Leivonen SK, Lazaridis K, Decock J, Chantry A, Edwards DR, Kähäri VM. TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2. Plos One. 8: e57474. PMID 23468994 DOI: 10.1371/Journal.Pone.0057474 |
0.422 |
|
| 2013 |
Decock J, Roghi C, Edwards DR. Matrix metalloproteinases: a dual role in breast cancer? Breast Cancer Management. 2: 353-356. DOI: 10.2217/Bmt.13.36 |
0.471 |
|
| 2012 |
Baren JP, Stewart GD, Stokes A, Gray K, Pennington CJ, O'Neill R, Deans DA, Paterson-Brown S, Riddick AC, Edwards DR, Fearon KC, Ross JA, Skipworth RJ. mRNA profiling of the cancer degradome in oesophago-gastric adenocarcinoma. British Journal of Cancer. 107: 143-9. PMID 22677901 DOI: 10.1038/Bjc.2012.239 |
0.495 |
|
| 2012 |
Eldred JA, Hodgkinson LM, Dawes LJ, Reddan JR, Edwards DR, Wormstone IM. MMP2 activity is critical for TGFβ2-induced matrix contraction--implications for fibrosis. Investigative Ophthalmology & Visual Science. 53: 4085-98. PMID 22618590 DOI: 10.1167/Iovs.12-9457 |
0.48 |
|
| 2012 |
Baren JP, Stewart GD, Stokes A, Gray K, Pennington CJ, Deans C, Paterson-Brown S, Riddick AC, Edwards DR, Fearon KC, Ross JA, Skipworth RJ. PMO-093 MRNA profiling of the cancer degradome in oesophago-gastric adenocarcinoma Gut. 61: A111.1-A111. DOI: 10.1136/Gutjnl-2012-302514B.93 |
0.505 |
|
| 2011 |
Elkington P, Shiomi T, Breen R, Nuttall RK, Ugarte-Gil CA, Walker NF, Saraiva L, Pedersen B, Mauri F, Lipman M, Edwards DR, Robertson BD, D'Armiento J, Friedland JS. MMP-1 drives immunopathology in human tuberculosis and transgenic mice. The Journal of Clinical Investigation. 121: 1827-33. PMID 21519144 DOI: 10.1172/Jci45666 |
0.475 |
|
| 2011 |
Decock J, Thirkettle S, Wagstaff L, Edwards DR. Matrix metalloproteinases: Protective roles in cancer Journal of Cellular and Molecular Medicine. 15: 1254-1265. PMID 21418514 DOI: 10.1111/J.1582-4934.2011.01302.X |
0.532 |
|
| 2011 |
Ramsay AK, McCracken SR, Soofi M, Fleming J, Yu AX, Ahmad I, Morland R, Machesky L, Nixon C, Edwards DR, Nuttall RK, Seywright M, Marquez R, Keller E, Leung HY. ERK5 signalling in prostate cancer promotes an invasive phenotype. British Journal of Cancer. 104: 664-72. PMID 21266977 DOI: 10.1038/Sj.Bjc.6606062 |
0.377 |
|
| 2011 |
Wagstaff L, Kelwick R, Decock J, Edwards DR. The roles of ADAMTS metalloproteinases in tumorigenesis and metastasis Frontiers in Bioscience. 16: 1861-1872. PMID 21196270 DOI: 10.2741/3827 |
0.381 |
|
| 2010 |
Hodgkinson LM, Wang L, Duncan G, Edwards DR, Wormstone IM. ADAM and ADAMTS gene expression in native and wound healing human lens epithelial cells. Molecular Vision. 16: 2765-76. PMID 21197111 |
0.352 |
|
| 2010 |
Cooley LS, Handsley MM, Zhou Z, Lafleur MA, Pennington CJ, Thompson EW, Pöschl E, Edwards DR. Reversible transdifferentiation of blood vascular endothelial cells to a lymphatic-like phenotype in vitro. Journal of Cell Science. 123: 3808-16. PMID 20940254 DOI: 10.1242/jcs.064279 |
0.378 |
|
| 2010 |
Ravenhill L, Wagstaff L, Edwards DR, Ellis V, Bass R. G-helix of maspin mediates effects on cell migration and adhesion. The Journal of Biological Chemistry. 285: 36285-92. PMID 20837467 DOI: 10.1074/Jbc.M110.177253 |
0.357 |
|
| 2010 |
Atkinson JM, Falconer RA, Edwards DR, Pennington CJ, Siller CS, Shnyder SD, Bibby MC, Patterson LH, Loadman PM, Gill JH. Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases. Cancer Research. 70: 6902-12. PMID 20663911 DOI: 10.1158/0008-5472.Can-10-1440 |
0.44 |
|
| 2010 |
Bass R, Edwards DR. ADAMs and protein disulfide isomerase: the key to regulated cell-surface protein ectodomain shedding? The Biochemical Journal. 428: e3-5. PMID 20504280 DOI: 10.1042/Bj20100568 |
0.344 |
|
| 2010 |
Green JA, Elkington PT, Pennington CJ, Roncaroli F, Dholakia S, Moores RC, Bullen A, Porter JC, Agranoff D, Edwards DR, Friedland JS. Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks. Journal of Immunology (Baltimore, Md. : 1950). 184: 6492-503. PMID 20483790 DOI: 10.4049/Jimmunol.0903811 |
0.525 |
|
| 2010 |
Barter MJ, Pybus L, Litherland GJ, Rowan AD, Clark IM, Edwards DR, Cawston TE, Young DA. HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 602-12. PMID 20470885 DOI: 10.1016/J.Matbio.2010.05.002 |
0.345 |
|
| 2010 |
Stokes A, Joutsa J, Ala-Aho R, Pitchers M, Pennington CJ, Martin C, Premachandra DJ, Okada Y, Peltonen J, Grénman R, James HA, Edwards DR, Kähäri VM. Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2022-35. PMID 20305301 DOI: 10.1158/1078-0432.Ccr-09-2525 |
0.47 |
|
| 2010 |
Pennington CJ, Edwards DR. Real-time PCR expression profiling of MMPs and TIMPs Methods in Molecular Biology (Clifton, N.J.). 622: 159-173. PMID 20135281 DOI: 10.1007/978-1-60327-299-5_9 |
0.467 |
|
| 2010 |
Lee M, Atkinson S, Rapti M, Handsley M, Curry V, Edwards D, Murphy G. The activity of a designer tissue inhibitor of metalloproteinases (TIMP)-1 against native membrane type 1 matrix metalloproteinase (MT1-MMP) in a cell-based environment. Cancer Letters. 290: 114-122. PMID 19815335 DOI: 10.1016/J.Canlet.2009.08.029 |
0.542 |
|
| 2010 |
Krüger A, Kates RE, Edwards DR. Avoiding spam in the proteolytic internet: Future strategies for anti-metastatic MMP inhibition Biochimica Et Biophysica Acta - Molecular Cell Research. 1803: 95-102. PMID 19800374 DOI: 10.1016/J.Bbamcr.2009.09.016 |
0.507 |
|
| 2010 |
Wagstaff L, Kelwick R, Decock J, Arnold H, Pennington C, Jaworski D, Edwards D. ADAMTS15 metalloproteinase inhibits breast cancer cell migration. Breast Cancer Research. 12: 15. DOI: 10.1186/Bcr2512 |
0.442 |
|
| 2009 |
Harvey AJ, Pennington CJ, Porter S, Burmi RS, Edwards DR, Court W, Eccles SA, Crompton MR. Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage. The American Journal of Pathology. 175: 1226-34. PMID 19661439 DOI: 10.2353/Ajpath.2009.080811 |
0.336 |
|
| 2009 |
Maretzky T, Le Gall SM, Worpenberg-Pietruk S, Eder J, Overall CM, Huang XY, Poghosyan Z, Edwards DR, Blobel CP. Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer. Cancer Research. 69: 4573-6. PMID 19487280 DOI: 10.1158/0008-5472.Can-08-4766 |
0.328 |
|
| 2009 |
Hancox RA, Allen MD, Holliday DL, Edwards DR, Pennington CJ, Guttery DS, Shaw JA, Walker RA, Pringle JH, Jones JL. Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms. Breast Cancer Research : Bcr. 11: R24. PMID 19405959 DOI: 10.1186/Bcr2251 |
0.435 |
|
| 2009 |
Boutet P, Agüera-González S, Atkinson S, Pennington CJ, Edwards DR, Murphy G, Reyburn HT, Valés-Gómez M. Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein. Journal of Immunology (Baltimore, Md. : 1950). 182: 49-53. PMID 19109134 DOI: 10.4049/Jimmunol.182.1.49 |
0.339 |
|
| 2009 |
Edwards DR, Handsley MM, Pennington CJ. The ADAM metalloproteinases Molecular Aspects of Medicine. 29: 258-289. PMID 18762209 DOI: 10.1016/J.Mam.2008.08.001 |
0.383 |
|
| 2008 |
Nielsen BS, Egeblad M, Rank F, Askautrud HA, Pennington CJ, Pedersen TX, Christensen IJ, Edwards DR, Werb Z, Lund LR. Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. Plos One. 3: e2959. PMID 18698413 DOI: 10.1371/Journal.Pone.0002959 |
0.515 |
|
| 2008 |
Stewart GD, Skipworth RJ, Pennington CJ, Lowrie AG, Deans DA, Edwards DR, Habib FK, Riddick AC, Fearon KC, Ross JA. Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines. British Journal of Cancer. 99: 126-32. PMID 18594538 DOI: 10.1038/Sj.Bjc.6604458 |
0.332 |
|
| 2008 |
Gutiérrez-Fernández A, Fueyo A, Folgueras AR, Garabaya C, Pennington CJ, Pilgrim S, Edwards DR, Holliday DL, Jones JL, Span PN, Sweep FC, Puente XS, López-OtÃn C. Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion. Cancer Research. 68: 2755-63. PMID 18413742 DOI: 10.1158/0008-5472.Can-07-5154 |
0.531 |
|
| 2008 |
Gerg M, Kopitz C, Schaten S, Tschukes A, Kahlert C, Stangl M, von Weyhern CW, Brücher BL, Edwards DR, Brand K, Krüger A. Distinct functionality of tumor cell-derived gelatinases during formation of liver metastases. Molecular Cancer Research : McR. 6: 341-51. PMID 18337444 DOI: 10.1158/1541-7786.Mcr-07-2032 |
0.539 |
|
| 2008 |
Zhong JL, Poghosyan Z, Pennington CJ, Scott X, Handsley MM, Warn A, Gavrilovic J, Honert K, Krüger A, Span PN, Sweep FC, Edwards DR. Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. Molecular Cancer Research : McR. 6: 383-94. PMID 18296648 DOI: 10.1158/1541-7786.Mcr-07-2028 |
0.366 |
|
| 2008 |
Clark IM, Swingler TE, Sampieri CL, Edwards DR. The regulation of matrix metalloproteinases and their inhibitors International Journal of Biochemistry and Cell Biology. 40: 1362-1378. PMID 18258475 DOI: 10.1016/J.Biocel.2007.12.006 |
0.529 |
|
| 2008 |
Folgueras AR, Fueyo A, García-Suárez O, Cox J, Astudillo A, Tortorella P, Campestre C, Gutiérrez-Fernández A, Fanjul-Fernández M, Pennington CJ, Edwards DR, Overall CM, López-Otín C. Collagenase-2 deficiency or inhibition impairs experimental autoimmune encephalomyelitis in mice. The Journal of Biological Chemistry. 283: 9465-74. PMID 18245084 DOI: 10.1074/Jbc.M709522200 |
0.492 |
|
| 2008 |
Sampieri CL, Nuttall RK, Young DA, Goldspink D, Clark IM, Edwards DR. Activation of p38 and JNK MAPK pathways abrogates requirement for new protein synthesis for phorbol ester mediated induction of select MMP and TIMP genes. Matrix Biology : Journal of the International Society For Matrix Biology. 27: 128-38. PMID 18029162 DOI: 10.1016/J.Matbio.2007.09.004 |
0.534 |
|
| 2008 |
Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank S, Edwards DR, Parker AE, Clark IM. Expression profiling of metalloproteinases and inhibitors in cartilage International Journal of Experimental Pathology. 85: A23-A23. DOI: 10.1111/J.0959-9673.2004.369Ac.X |
0.534 |
|
| 2008 |
Young DA, Edwards DR, Clark IM. The role of acetylation in Timp-1 regulation International Journal of Experimental Pathology. 85: A18-A19. DOI: 10.1111/J.0959-9673.2004.0369W.X |
0.477 |
|
| 2007 |
Kopitz C, Gerg M, Bandapalli OR, Ister D, Pennington CJ, Hauser S, Flechsig C, Krell HW, Antolovic D, Brew K, Nagase H, Stangl M, von Weyhern CW, Brücher BL, Brand K, ... ... Edwards DR, et al. Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer Research. 67: 8615-23. PMID 17875701 DOI: 10.1158/0008-5472.Can-07-0232 |
0.478 |
|
| 2007 |
Hodgkinson LM, Duncan G, Wang L, Pennington CJ, Edwards DR, Wormstone IM. MMP and TIMP expression in quiescent, dividing, and differentiating human lens cells. Investigative Ophthalmology & Visual Science. 48: 4192-9. PMID 17724206 DOI: 10.1167/Iovs.06-1371 |
0.566 |
|
| 2007 |
Atkinson JM, Pennington CJ, Martin SW, Anikin VA, Mearns AJ, Loadman PM, Edwards DR, Gill JH. Membrane type matrix metalloproteinases (MMPs) show differential expression in non-small cell lung cancer (NSCLC) compared to normal lung: correlation of MMP-14 mRNA expression and proteolytic activity. European Journal of Cancer (Oxford, England : 1990). 43: 1764-71. PMID 17600697 DOI: 10.1016/J.Ejca.2007.05.009 |
0.531 |
|
| 2007 |
Rooprai HK, Kyriazis I, Nuttall RK, Edwards DR, Zicha D, Aubyn D, Davies D, Gullan R, Pilkington GJ. Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro. International Journal of Oncology. 30: 1263-71. PMID 17390030 DOI: 10.3892/Ijo.30.5.1263 |
0.366 |
|
| 2007 |
Nuttall RK, Silva C, Hader W, Bar-Or A, Patel KD, Edwards DR, Yong VW. Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia Glia. 55: 516-526. PMID 17216595 DOI: 10.1002/Glia.20478 |
0.451 |
|
| 2007 |
Harris JE, Nuttall RK, Elkington PT, Green JA, Horncastle DE, Graeber MB, Edwards DR, Friedland JS. Monocyte-astrocyte networks regulate matrix metalloproteinase gene expression and secretion in central nervous system tuberculosis in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 178: 1199-207. PMID 17202385 DOI: 10.4049/Jimmunol.178.2.1199 |
0.518 |
|
| 2006 |
Sarkar S, Nuttall RK, Liu S, Edwards DR, Yong VW. Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12 Cancer Research. 66: 11771-11780. PMID 17178873 DOI: 10.1158/0008-5472.Can-05-0470 |
0.52 |
|
| 2006 |
García-Alvarez J, Ramirez R, Sampieri CL, Nuttall RK, Edwards DR, Selman M, Pardo A. Membrane type-matrix metalloproteinases in idiopathic pulmonary fibrosis. Sarcoidosis, Vasculitis, and Diffuse Lung Diseases : Official Journal of Wasog / World Association of Sarcoidosis and Other Granulomatous Disorders. 23: 13-21. PMID 16933466 |
0.39 |
|
| 2006 |
García-Alvarez J, Ramirez R, Checa M, Nuttall RK, Sampieri CL, Edwards DR, Selman M, Pardo A. Tissue inhibitor of metalloproteinase-3 is up-regulated by transforming growth factor-beta1 in vitro and expressed in fibroblastic foci in vivo in idiopathic pulmonary fibrosis. Experimental Lung Research. 32: 201-14. PMID 16908447 DOI: 10.1080/01902140600817481 |
0.428 |
|
| 2006 |
Chabottaux V, Sounni NE, Pennington CJ, English WR, van den Brûle F, Blacher S, Gilles C, Munaut C, Maquoi E, Lopez-Otin C, Murphy G, Edwards DR, Foidart JM, Noël A. Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Research. 66: 5165-72. PMID 16707440 DOI: 10.1158/0008-5472.Can-05-3012 |
0.528 |
|
| 2006 |
Jones GC, Corps AN, Pennington CJ, Clark IM, Edwards DR, Bradley MM, Hazleman BL, Riley GP. Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis and Rheumatism. 54: 832-42. PMID 16508964 DOI: 10.1002/Art.21672 |
0.485 |
|
| 2006 |
Wallard MJ, Pennington CJ, Veerakumarasivam A, Burtt G, Mills IG, Warren A, Leung HY, Murphy G, Edwards DR, Neal DE, Kelly JD. Comprehensive profiling and localisation of the matrix metalloproteinases in urothelial carcinoma. British Journal of Cancer. 94: 569-77. PMID 16465195 DOI: 10.1038/Sj.Bjc.6602931 |
0.557 |
|
| 2006 |
Porter S, Span PN, Sweep FC, Tjan-Heijnen VC, Pennington CJ, Pedersen TX, Johnsen M, Lund LR, Rømer J, Edwards DR. ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma. International Journal of Cancer. 118: 1241-7. PMID 16152618 DOI: 10.1002/Ijc.21476 |
0.307 |
|
| 2006 |
Atkinson J, Falconer R, Pennington C, Martin S, Anikin V, Mearns A, Edwards D, Patterson L, Loadman P, Gill J. 417 POSTER Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) is overexpressed in lung cancer and can cleave peptide-conjugates European Journal of Cancer Supplements. 4: 128. DOI: 10.1016/S1359-6349(06)70422-0 |
0.322 |
|
| 2005 |
Elkington PT, Nuttall RK, Boyle JJ, O'Kane CM, Horncastle DE, Edwards DR, Friedland JS. Mycobacterium tuberculosis, but not vaccine BCG, specifically upregulates matrix metalloproteinase-1. American Journal of Respiratory and Critical Care Medicine. 172: 1596-604. PMID 16141443 DOI: 10.1164/Rccm.200505-753Oc |
0.411 |
|
| 2005 |
Weaver A, Goncalves da Silva A, Nuttall RK, Edwards DR, Shapiro SD, Rivest S, Yong VW. An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1668-70. PMID 16081501 DOI: 10.1096/Fj.04-2030Fje |
0.517 |
|
| 2005 |
Kassiri Z, Oudit GY, Sanchez O, Dawood F, Mohammed FF, Nuttall RK, Edwards DR, Liu PP, Backx PH, Khokha R. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Circulation Research. 97: 380-90. PMID 16037568 DOI: 10.1161/01.Res.0000178789.16929.Cf |
0.487 |
|
| 2005 |
Singh RJ, Mason JC, Lidington EA, Edwards DR, Nuttall RK, Khokha R, Knauper V, Murphy G, Gavrilovic J. Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3. Cardiovascular Research. 67: 39-49. PMID 15949468 DOI: 10.1016/J.Cardiores.2005.02.020 |
0.43 |
|
| 2005 |
Riddick AC, Shukla CJ, Pennington CJ, Bass R, Nuttall RK, Hogan A, Sethia KK, Ellis V, Collins AT, Maitland NJ, Ball RY, Edwards DR. Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues. British Journal of Cancer. 92: 2171-80. PMID 15928670 DOI: 10.1038/Sj.Bjc.6602630 |
0.544 |
|
| 2005 |
Young DA, Lakey RL, Pennington CJ, Jones D, Kevorkian L, Edwards DR, Cawston TE, Clark IM. Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Research & Therapy. 7: R503-12. PMID 15899037 DOI: 10.1186/Ar1702 |
0.502 |
|
| 2005 |
Young DA, Billingham O, Sampieri CL, Edwards DR, Clark IM. Differential effects of histone deacetylase inhibitors on phorbol ester- and TGF-beta1 induced murine tissue inhibitor of metalloproteinases-1 gene expression. The Febs Journal. 272: 1912-26. PMID 15819885 DOI: 10.1111/J.1742-4658.2005.04622.X |
0.395 |
|
| 2005 |
Pedersen TX, Pennington CJ, Almholt K, Christensen IJ, Nielsen BS, Edwards DR, Rømer J, Danø K, Johnsen M. Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas. Carcinogenesis. 26: 1233-40. PMID 15760918 DOI: 10.1093/Carcin/Bgi065 |
0.478 |
|
| 2005 |
Handsley MM, Edwards DR. Metalloproteinases and their inhibitors in tumor angiogenesis International Journal of Cancer. 115: 849-860. PMID 15729716 DOI: 10.1002/Ijc.20945 |
0.508 |
|
| 2005 |
Mohammed FF, Pennington CJ, Kassiri Z, Rubin JS, Soloway PD, Ruther U, Edwards DR, Khokha R. Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration. Hepatology (Baltimore, Md.). 41: 857-67. PMID 15726641 DOI: 10.1002/Hep.20618 |
0.536 |
|
| 2005 |
Denton CP, Lindahl GE, Khan K, Shiwen X, Ong VH, Gaspar NJ, Lazaridis K, Edwards DR, Leask A, Eastwood M, Leoni P, Renzoni EA, Bou Gharios G, Abraham DJ, Black CM. Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k). The Journal of Biological Chemistry. 280: 16053-65. PMID 15708853 DOI: 10.1074/Jbc.M413134200 |
0.42 |
|
| 2005 |
Porter S, Clark IM, Kevorkian L, Edwards DR. The ADMTS metalloproteinases Biochemical Journal. 386: 15-27. PMID 15554875 DOI: 10.1042/Bj20040424 |
0.416 |
|
| 2005 |
Sudre L, Cheung F, Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank S, Edwards DR, Parker AE, Clark IM, Boubriak OA, Urban JPG, Cui Z, et al. British society for matrix biology autumn meeting International Journal of Experimental Pathology. 86: A1-A56. DOI: 10.1111/J.0959-9673.2005.00426.X |
0.398 |
|
| 2005 |
Wallard M, Pennington C, Veerakumarasivam A, Murphy G, Edwards D, Neal D, Kelly JD, Sahadevan K, Leung HY. 769: Profiling and Localisation of the Matrix Metalloproteinases in Bladder Cancer Journal of Urology. 173: 208-209. DOI: 10.1016/S0022-5347(18)34938-3 |
0.406 |
|
| 2004 |
Toft-Hansen H, Nuttall RK, Edwards DR, Owens T. Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5209-18. PMID 15470066 DOI: 10.4049/Jimmunol.173.8.5209 |
0.556 |
|
| 2004 |
Young DA, Gavrilov S, Pennington CJ, Nuttall RK, Edwards DR, Kitsis RN, Clark IM. Expression of metalloproteinases and inhibitors in the differentiation of P19CL6 cells into cardiac myocytes. Biochemical and Biophysical Research Communications. 322: 759-65. PMID 15336529 DOI: 10.1016/J.Bbrc.2004.07.178 |
0.422 |
|
| 2004 |
Edwards DR. TIMP-3 and endocrine therapy of breast cancer: An apoptosis connection emerges Journal of Pathology. 202: 391-394. PMID 15095265 DOI: 10.1002/Path.1548 |
0.493 |
|
| 2004 |
Porter S, Scott SD, Sassoon EM, Williams MR, Jones JL, Girling AC, Ball RY, Edwards DR. Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2429-40. PMID 15073121 DOI: 10.1158/1078-0432.Ccr-0398-3 |
0.366 |
|
| 2004 |
Nuttall RK, Sampieri CL, Pennington CJ, Gill SE, Schultz GA, Edwards DR. Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. Febs Letters. 563: 129-34. PMID 15063736 DOI: 10.1016/S0014-5793(04)00281-9 |
0.555 |
|
| 2004 |
Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank SM, Edwards DR, Parker AE, Clark IM. Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis and Rheumatism. 50: 131-41. PMID 14730609 DOI: 10.1002/Art.11433 |
0.529 |
|
| 2003 |
Banke IJ, Arlt MJ, Pennington C, Kopitz C, Steinmetzer T, Schweinitz A, Gansbacher B, Quigley JP, Edwards DR, Stürzebecher J, Krüger A. Increase of anti-metastatic efficacy by selectivity- but not affinity-optimization of synthetic serine protease inhibitors. Biological Chemistry. 384: 1515-25. PMID 14669995 DOI: 10.1515/Bc.2003.168 |
0.336 |
|
| 2003 |
Wells JE, Rice TK, Nuttall RK, Edwards DR, Zekki H, Rivest S, Yong VW. An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10107-15. PMID 14602826 DOI: 10.1523/Jneurosci.23-31-10107.2003 |
0.436 |
|
| 2003 |
Platt CI, Krekoski CA, Ward RV, Edwards DR, Gavrilovic J. Extracellular matrix and matrix metalloproteinases in sciatic nerve. Journal of Neuroscience Research. 74: 417-29. PMID 14598318 DOI: 10.1002/Jnr.10783 |
0.475 |
|
| 2003 |
Lafleur MA, Handsley MM, Edwards DR. Metalloproteinases and their inhibitors in angiogenesis Expert Reviews in Molecular Medicine. 5: 1-39. PMID 14585170 DOI: 10.1017/S1462399403006628 |
0.519 |
|
| 2003 |
Clark IM, Young DA, Edwards DR, Stearns ME, Hu Y, Wang M. TIMP-I enhancer sequence - Real or bacterial? [1] (multiple letters) British Journal of Cancer. 89: 1812-1813. PMID 14583788 DOI: 10.1038/Sj.Bjc.6601353 |
0.301 |
|
| 2003 |
Worley JR, Baugh MD, Hughes DA, Edwards DR, Hogan A, Sampson MJ, Gavrilovic J. Metalloproteinase expression in PMA-stimulated THP-1 cells. Effects of peroxisome proliferator-activated receptor-gamma (PPAR gamma) agonists and 9-cis-retinoic acid. The Journal of Biological Chemistry. 278: 51340-6. PMID 14534304 DOI: 10.1074/jbc.M310865200 |
0.352 |
|
| 2003 |
Moorehead RA, Hojilla CV, De Belle I, Wood GA, Fata JE, Adamson ED, Watson KLM, Edwards DR, Khokha R. Insulin-like Growth Factor-II Regulates PTEN Expression in the Mammary Gland Journal of Biological Chemistry. 278: 50422-50427. PMID 14517213 DOI: 10.1074/Jbc.M306894200 |
0.33 |
|
| 2003 |
Bar-Or A, Nuttall RK, Duddy M, Alter A, Kim HJ, Ifergan I, Pennington CJ, Bourgoin P, Edwards DR, Yong VW. Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis. Brain : a Journal of Neurology. 126: 2738-49. PMID 14506071 DOI: 10.1093/Brain/Awg285 |
0.54 |
|
| 2003 |
Alter A, Duddy M, Hebert S, Biernacki K, Prat A, Antel JP, Yong VW, Nuttall RK, Pennington CJ, Edwards DR, Bar-Or A. Determinants of human B cell migration across brain endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4497-505. PMID 12707326 DOI: 10.4049/Jimmunol.170.9.4497 |
0.389 |
|
| 2003 |
Nuttall RK, Pennington CJ, Taplin J, Wheal A, Yong VW, Forsyth PA, Edwards DR. Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells Molecular Cancer Research. 1: 333-345. PMID 12651907 |
0.476 |
|
| 2003 |
Palosaari H, Pennington CJ, Larmas M, Edwards DR, Tjäderhane L, Salo T. Expression profile of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in mature human odontoblasts and pulp tissue. European Journal of Oral Sciences. 111: 117-27. PMID 12648263 DOI: 10.1034/J.1600-0722.2003.00026.X |
0.563 |
|
| 2003 |
Worley JR, Thompkins PB, Lee MH, Hutton M, Soloway P, Edwards DR, Murphy G, Knäuper V. Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP). The Biochemical Journal. 372: 799-809. PMID 12630911 DOI: 10.1042/Bj20021573 |
0.53 |
|
| 2003 |
Hall MC, Young DA, Waters JG, Rowan AD, Chantry A, Edwards DR, Clark IM. The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1. The Journal of Biological Chemistry. 278: 10304-13. PMID 12525489 DOI: 10.1074/jbc.M212334200 |
0.335 |
|
| 2002 |
Price JS, Waters JG, Darrah C, Pennington C, Edwards DR, Donell ST, Clark IM. The role of chondrocyte senescence in osteoarthritis. Aging Cell. 1: 57-65. PMID 12882354 DOI: 10.1046/J.1474-9728.2002.00008.X |
0.441 |
|
| 2002 |
van Kempen LC, Rhee JS, Dehne K, Lee J, Edwards DR, Coussens LM. Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment. Differentiation; Research in Biological Diversity. 70: 610-23. PMID 12492502 DOI: 10.1046/J.1432-0436.2002.700914.X |
0.553 |
|
| 2002 |
Radomski A, Jurasz P, Sanders EJ, Overall CM, Bigg HF, Edwards DR, Radomski MW. Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets British Journal of Pharmacology. 137: 1330-1338. PMID 12466243 DOI: 10.1038/Sj.Bjp.0704936 |
0.388 |
|
| 2002 |
Arlt M, Kopitz C, Pennington C, Watson KLM, Krell HW, Bode W, Gansbacher B, Khokha R, Edwards DR, Krüger A. Increase in gelatinase-specificity of matrix metalloproteinase inhibitors correlates with antimetastatic efficacy in a T-cell lymphoma model Cancer Research. 62: 5543-5550. PMID 12359766 |
0.44 |
|
| 2002 |
Baker AH, Edwards DR, Murphy G. Metalloproteinase inhibitors: Biological actions and therapeutic opportunities Journal of Cell Science. 115: 3719-3727. PMID 12235282 DOI: 10.1242/Jcs.00063 |
0.535 |
|
| 2002 |
Wall SJ, Bevan D, Thomas DW, Harding KG, Edwards DR, Murphy G. Differential expression of matrix metalloproteinases during impaired wound healing of the diabetes mouse. The Journal of Investigative Dermatology. 119: 91-8. PMID 12164930 DOI: 10.1046/J.1523-1747.2002.01779.X |
0.362 |
|
| 2002 |
Lafleur MA, Handsley MM, Knäuper V, Murphy G, Edwards DR. Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs). Journal of Cell Science. 115: 3427-38. PMID 12154073 |
0.453 |
|
| 2002 |
Young DA, Phillips BW, Lundy C, Nuttall RK, Hogan A, Schultz GA, Leco KJ, Clark IM, Edwards DR. Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene. The Biochemical Journal. 364: 89-99. PMID 11988080 DOI: 10.1042/Bj3640089 |
0.734 |
|
| 2002 |
Koshy PJ, Lundy CJ, Rowan AD, Porter S, Edwards DR, Hogan A, Clark IM, Cawston TE. The modulation of matrix metalloproteinase and ADAM gene expression in human chondrocytes by interleukin-1 and oncostatin M: a time-course study using real-time quantitative reverse transcription-polymerase chain reaction. Arthritis and Rheumatism. 46: 961-7. PMID 11953973 DOI: 10.1002/Art.10212 |
0.44 |
|
| 2002 |
Jung JC, Leco KJ, Edwards DR, Fini ME. Matrix metalloproteinases mediate the dismantling of mesenchymal structures in the tadpole tail during thyroid hormone-induced tail resorption Developmental Dynamics. 223: 402-413. PMID 11891989 DOI: 10.1002/Dvdy.10069 |
0.538 |
|
| 2002 |
Yeow KM, Kishnani NS, Hutton M, Hawkes SP, Murphy G, Edwards DR. Sorsby's fundus dystrophy tissue inhibitor of metalloproteinases-3 (TIMP-3) mutants have unimpaired matrix metalloproteinase inhibitory activities, but affect cell adhesion to the extracellular matrix. Matrix Biology : Journal of the International Society For Matrix Biology. 21: 75-88. PMID 11827795 DOI: 10.1016/S0945-053X(01)00180-9 |
0.745 |
|
| 2002 |
Qi JH, Ebrahem Q, Yeow K, Edwards DR, Fox PL, Anand-Apte B. Expression of Sorsby's fundus dystrophy mutations in human retinal pigment epithelial cells reduces matrix metalloproteinase inhibition and may promote angiogenesis. The Journal of Biological Chemistry. 277: 13394-400. PMID 11821400 DOI: 10.1074/Jbc.M110870200 |
0.758 |
|
| 2002 |
Stringa E, Murphy G, Edwards D, Gavrilović J. Potential roles of metalloproteinases in cell migration Biochemical Society Transactions. 30: A21-A21. DOI: 10.1042/Bst030A021 |
0.415 |
|
| 2001 |
Groft LL, Muzik H, Rewcastle NB, Johnston RN, Knäuper V, Lafleur MA, Forsyth PA, Edwards DR. Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas. British Journal of Cancer. 85: 55-63. PMID 11437402 DOI: 10.1054/Bjoc.2001.1854 |
0.55 |
|
| 2001 |
Yong VW, Power C, Forsyth P, Edwards DR. Metalloproteinases in biology and pathology of the nervous system Nature Reviews Neuroscience. 2: 502-511. PMID 11433375 DOI: 10.1038/35081571 |
0.508 |
|
| 2001 |
Lafleur MA, Hollenberg MD, Atkinson SJ, Knäuper V, Murphy G, Edwards DR. Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species Biochemical Journal. 357: 107-115. PMID 11415441 DOI: 10.1042/0264-6021:3570107 |
0.457 |
|
| 2001 |
Lafleur MA, Forsyth PA, Atkinson SJ, Murphy G, Edwards DR. Perivascular cells regulate endothelial membrane type-1 matrix metalloproteinase activity Biochemical and Biophysical Research Communications. 282: 463-473. PMID 11401482 DOI: 10.1006/Bbrc.2001.4596 |
0.551 |
|
| 2001 |
Whiteside EJ, Jackson MM, Herington AC, Edwards DR, Harvey MB. Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-3 are key regulators of extracellular matrix degration by mouse embryos Biology of Reproduction. 64: 1331-1337. PMID 11319136 DOI: 10.1095/Biolreprod64.5.1331 |
0.554 |
|
| 2001 |
Kim H, Oda T, López-Guisa J, Wing D, Edwards DR, Soloway PD, Eddy AA. TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy. Journal of the American Society of Nephrology : Jasn. 12: 736-48. PMID 11274235 |
0.351 |
|
| 2001 |
Wong H, Muzik H, Groft LL, Lafleur MA, Matouk C, Forsyth PA, Schultz GA, Wall SJ, Edwards DR. Monitoring MMP and TIMP mRNA expression by RT-PCR. Methods in Molecular Biology (Clifton, N.J.). 151: 305-20. PMID 11217307 DOI: 10.1385/1-59259-046-2:305 |
0.489 |
|
| 2001 |
Yeow KM, Phillips BW, Beaudry PP, Leco KJ, Murphy G, Edwards DR. Expression of MMPs and TIMPs in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 151: 181-9. PMID 11217298 DOI: 10.1385/1-59259-046-2:181 |
0.807 |
|
| 2001 |
LAFLEUR MA, HOLLENBERG MD, ATKINSON SJ, KNÄUPER V, MURPHY G, EDWARDS DR. Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species Biochemical Journal. 357: 107-115. DOI: 10.1042/Bj3570107 |
0.544 |
|
| 2000 |
Raithatha SA, Muzik H, Muzik H, Rewcastle NB, Johnston RN, Edwards DR, Forsyth PA. Localization of gelatinase-A and gelatinase-B mRNA and protein in human gliomas. Neuro-Oncology. 2: 145-50. PMID 11302334 DOI: 10.1093/Neuonc/2.3.145 |
0.505 |
|
| 2000 |
Dean G, Young DA, Edwards DR, Clark IM. The human tissue inhibitor of metalloproteinases (TIMP)-1 gene contains repressive elements within the promoter and intron 1 Journal of Biological Chemistry. 275: 32664-32671. PMID 11032844 DOI: 10.1074/Jbc.275.42.32664 |
0.361 |
|
| 2000 |
Harvey P, Clark IM, Jaurand MC, Warn RM, Edwards DR. Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinases British Journal of Cancer. 83: 1147-1153. PMID 11027427 DOI: 10.1054/bjoc.2000.1445 |
0.479 |
|
| 1999 |
Phillips BW, Sharma R, Leco PA, Edwards DR. A sequence-selective single-strand DNA-binding protein regulates basal transcription of the murine tissue inhibitor of metalloproteinases-1 (Timp- 1) gene Journal of Biological Chemistry. 274: 22197-22207. PMID 10428785 DOI: 10.1074/Jbc.274.32.22197 |
0.7 |
|
| 1999 |
Kossakowska AE, Medlicott SA, Edwards DR, Guyn L, Stabbler AL, Sutherland LR, Urbanski SJ. Elevated plasma gelatinase A (MMP-2) activity is associated with quiescent Crohn's Disease. Annals of the New York Academy of Sciences. 878: 578-80. PMID 10415778 DOI: 10.1111/J.1749-6632.1999.Tb07732.X |
0.391 |
|
| 1999 |
Shalinsky DR, Brekken J, Zou H, Mcdermott CD, Forsyth P, Edwards D, Margosiak S, Bender S, Truitt G, Wood A, Varki NM, Appelt K. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Annals of the New York Academy of Sciences. 878: 236-270. PMID 10415735 DOI: 10.1111/J.1749-6632.1999.Tb07689.X |
0.363 |
|
| 1999 |
Bugno M, Witek B, Bereta J, Bereta M, Edwards DR, Kordula T. Reprogramming of TIMP-1 and TIMP-3 expression profiles in brain microvascular endothelial cells and astrocytes in response to proinflammatory cytokines Febs Letters. 448: 9-14. PMID 10217399 DOI: 10.1016/S0014-5793(99)00323-3 |
0.447 |
|
| 1999 |
Frölichsthal-Schoeller P, Vescovi AL, Krekoski CA, Murphy G, Edwards DR, Forsyth P. Expression and modulation of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinases in human embryonic CNS stem cells. Neuroreport. 10: 345-51. PMID 10203333 DOI: 10.1097/00001756-199902050-00025 |
0.535 |
|
| 1999 |
Oh LYS, Larsen PH, Krekoski CA, Edwards DR, Donovan F, Werb Z, Yong VW. Matrix Metalloproteinase-9/Gelatinase B Is Required for Process Outgrowth by Oligodendrocytes The Journal of Neuroscience. 19: 8464-8475. DOI: 10.1523/Jneurosci.19-19-08464.1999 |
0.487 |
|
| 1999 |
Kossakowska AE, Edwards DR, Prusinkiewicz C, Zhang MC, Guo D, Urbanski SJ, Grogan T, Marquez LA, Janowska-Wieczorek A. Interleukin-6 Regulation of Matrix Metalloproteinase (MMP-2 and MMP-9) and Tissue Inhibitor of Metalloproteinase (TIMP-1) Expression in Malignant Non-Hodgkin’s Lymphomas Blood. 94: 2080-2089. DOI: 10.1182/blood.v94.6.2080.418k30_2080_2089 |
0.437 |
|
| 1999 |
Kossakowska AE, Edwards DR, Prusinkiewicz C, Zhang MC, Guo D, Urbanski SJ, Grogan T, Marquez LA, Janowska-Wieczorek A. Interleukin-6 Regulation of Matrix Metalloproteinase (MMP-2 and MMP-9) and Tissue Inhibitor of Metalloproteinase (TIMP-1) Expression in Malignant Non-Hodgkin’s Lymphomas Blood. 94: 2080-2089. DOI: 10.1182/Blood.V94.6.2080 |
0.527 |
|
| 1999 |
Janowska-Wieczorek A, Marquez LA, Nabholtz J, Cabuhat ML, Montaño J, Chang H, Rozmus J, Russell JA, Edwards DR, Turner AR. Growth Factors and Cytokines Upregulate Gelatinase Expression in Bone Marrow CD34+ Cells and Their Transmigration Through Reconstituted Basement Membrane Blood. 93: 3379-3390. DOI: 10.1182/Blood.V93.10.3379.410K09_3379_3390 |
0.425 |
|
| 1999 |
Janowska-Wieczorek A, Marquez L, Matsuzaki A, Hashmi H, Larratt L, Boshkov L, Turner A, Zhang M, Edwards D, Kossakowska A. Expression of matrix metalloproteinases (MMP-2 and -9) and tissue inhibitors of metalloproteinases (TIMP-1 and -2) in acute myelogenous leukaemia blasts: comparison with normal bone marrow cells British Journal of Haematology. 105: 402-411. DOI: 10.1111/J.1365-2141.1999.01352.X |
0.511 |
|
| 1999 |
Forsyth PA, Wong H, Laing TD, Rewcastle NB, Morris DG, Muzik H, Leco KJ, Johnston RN, Brasher PMA, Sutherland G, Edwards DR. Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas British Journal of Cancer. 79: 1828-1835. DOI: 10.1038/Sj.Bjc.6990291 |
0.553 |
|
| 1998 |
Kossakowska AE, Edwards DR, Lee SS, Urbanski LS, Stabbler AL, Zhang CL, Phillips BW, Zhang Y, Urbanski SJ. Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis. The American Journal of Pathology. 153: 1895-902. PMID 9846979 DOI: 10.1016/S0002-9440(10)65703-3 |
0.772 |
|
| 1998 |
Edwards DR, Murphy G. Proteases - Invasion and more Nature. 394: 527-528. PMID 9707109 DOI: 10.1038/28961 |
0.309 |
|
| 1998 |
Forsyth PA, Laing TD, Gibson AW, Rewcastle NB, Brasher P, Sutherland G, Johnston RN, Edwards DR. High levels of gelatinase-B and active gelatinase-A in metastatic glioblastoma. Journal of Neuro-Oncology. 36: 21-9. PMID 9525822 DOI: 10.1023/A:1005879027267 |
0.325 |
|
| 1998 |
Yong VW, Krekoski CA, Forsyth PA, Bell R, Edwards DR. Matrix metalloproteinases and diseases of the CNS Trends in Neurosciences. 21: 75-80. PMID 9498303 DOI: 10.1016/S0166-2236(97)01169-7 |
0.509 |
|
| 1998 |
Botelho FM, Edwards DR, Richards CD. Oncostatin M stimulates c-Fos to bind a transcriptionally responsive AP- 1 element within the tissue inhibitor of metalloproteinase-1 promoter Journal of Biological Chemistry. 273: 5211-5218. PMID 9478976 DOI: 10.1074/Jbc.273.9.5211 |
0.341 |
|
| 1998 |
Kossakowska AE, Hinek A, Edwards DR, Lim MS, Zhang CL, Breitman DR, Prusinkiewicz C, Stabbler AL, Urbanski LS, Urbanski SJ. Proteolytic activity of human non-Hodgkin's lymphomas. The American Journal of Pathology. 152: 565-76. PMID 9466583 |
0.585 |
|
| 1997 |
Clark AW, Krekoski CA, Bou SS, Chapman KR, Edwards DR. Increased gelatinase A (MMP-2) and gelatinase B (MMP-9) activities in human brain after focal ischemia. Neuroscience Letters. 238: 53-6. PMID 9464653 DOI: 10.1016/S0304-3940(97)00859-8 |
0.522 |
|
| 1997 |
Leco KJ, Harvey MB, Hogan A, Copeland NG, Gilbert DJ, Jenkins NA, Edwards DR, Schultz GA. Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse Developmental Genetics. 21: 55-60. PMID 9291580 DOI: 10.1002/(Sici)1520-6408(1997)21:1<55::Aid-Dvg6>3.0.Co;2-7 |
0.504 |
|
| 1997 |
Das SK, Yano S, Wang J, Edwards DR, Nagase H, Dey SK. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri-implantation period. Developmental Genetics. 21: 44-54. PMID 9291579 DOI: 10.1002/(Sici)1520-6408(1997)21:1<44::Aid-Dvg5>3.0.Co;2-8 |
0.516 |
|
| 1997 |
Clark IM, Rowan AD, Edwards DR, Bech-Hansen T, Mann DA, Bahr MJ, Cawston TE. Transcriptional activity of the human tissue inhibitor of metalloproteinases 1 (TIMP-1) gene in fibroblasts involves elements in the promoter, exon 1 and intron 1. The Biochemical Journal. 611-7. PMID 9182725 DOI: 10.1042/Bj3240611 |
0.459 |
|
| 1997 |
Leco KJ, Apte SS, Taniguchi GT, Hawkes SP, Khokha R, Schultz GA, Edwards DR. Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues. Febs Letters. 401: 213-7. PMID 9013889 DOI: 10.1016/S0014-5793(96)01474-3 |
0.48 |
|
| 1996 |
Leco KJ, Edwards DR, Schultz GA. Tissue inhibitor of metalloproteinases-3 is the major metalloproteinase inhibitor in the decidualizing murine uterus Molecular Reproduction and Development. 45: 458-465. PMID 8956284 DOI: 10.1002/(Sici)1098-2795(199612)45:4<458::Aid-Mrd8>3.0.Co;2-Q |
0.529 |
|
| 1996 |
Sharmela Inderdeo D, Edwards DR, Han VKM, Khokha R. Temporal and spatial expression of tissue inhibitors of metalloproteinases during the natural ovulatory cycle of the mouse Biology of Reproduction. 55: 498-508. PMID 8862765 DOI: 10.1095/Biolreprod55.3.498 |
0.414 |
|
| 1996 |
Edwards DR, Leco KJ, Beaudry PP, Atadja PW, Veillette C, Riabowol KT. Differential effects of transforming growth factor-beta 1 on the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in young and old human fibroblasts. Experimental Gerontology. 31: 207-23. PMID 8706790 DOI: 10.1016/0531-5565(95)02010-1 |
0.514 |
|
| 1996 |
Edwards DR, Beaudry PP, Laing TD, Kowal V, Leco KJ, Leco PA, Lim MS. The roles of tissue inhibitors of metalloproteinases in tissue remodelling and cell growth. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 20: S9-15. PMID 8680484 |
0.66 |
|
| 1996 |
Kossakowska AE, Huchcroft SA, Urbanski SJ, Edwards DR. Comparative analysis of the expression patterns of metalloproteinases and their inhibitors in breast neoplasia, sporadic colorectal neoplasia, pulmonary carcinomas and malignant non-Hodgkin's lymphomas in humans British Journal of Cancer. 73: 1401-1408. PMID 8645587 DOI: 10.1038/Bjc.1996.266 |
0.543 |
|
| 1995 |
Roeb E, Rose-John S, Erren A, Edwards DR, Matern S, Graeve L, Heinrich PC. Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2. Febs Letters. 357: 33-6. PMID 8001673 DOI: 10.1016/0014-5793(94)01301-G |
0.406 |
|
| 1995 |
Harvey MB, Leco KJ, Arcellana-panlilio MY, Zhang X, Edwards DR, Schultz GA. Endocrinology and paracrinology: Roles of growth factors during peri-implantation development Human Reproduction. 10: 712-718. PMID 7782459 DOI: 10.1093/Oxfordjournals.Humrep.A136021 |
0.375 |
|
| 1995 |
Nothnick WB, Edwards DR, Leco KJ, Curry TE. Expression and activity of ovarian tissue inhibitors of metalloproteinases during pseudopregnancy in the rat Biology of Reproduction. 53: 684-691. PMID 7578694 DOI: 10.1095/Biolreprod53.3.684 |
0.465 |
|
| 1995 |
Harvey MB, Leco KJ, Arcellana-Panlilio MY, Zhang X, Edwards DR, Schurtz GA. Roles of growth factors during peri-implantation development Molecular Human Reproduction. 1: 14-20. DOI: 10.1093/Molehr/1.1.14 |
0.375 |
|
| 1994 |
Edwards DR. Cell signalling and the control of gene transcription Trends in Pharmacological Sciences. 15: 239-244. PMID 7940986 DOI: 10.1016/0165-6147(94)90318-2 |
0.316 |
|
| 1993 |
Denhardt DT, Feng B, Edwards DR, Cocuzzi ET, Malyankar UM. Tissue inhibitor of metalloproteinases (TIMP, aka EPA): Structure, control of expression and biological functions Pharmacology and Therapeutics. 59: 329-341. PMID 8309995 DOI: 10.1016/0163-7258(93)90074-N |
0.508 |
|
| 1993 |
Urbanski SJ, Edwards DR, Hershfield N, Huchcroft SA, Shaffer E, Sutherland L, Kossakowska AE. Expression Pattern of Metalloproteinases and Their Inhibitors Changes with the Progression of Human Sporadic Colorectal Neoplasia Diagnostic Molecular Pathology. 2: 81-89. DOI: 10.1097/00019606-199300020-00013 |
0.556 |
|
| 1993 |
Roeb E, Graeve L, Hoffmann R, Decker K, Edwards DR, Heinrich PC. Regulation of tissue inhibitor of metalloproteinases-1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures Hepatology. 18: 1437-1442. DOI: 10.1002/Hep.1840180624 |
0.466 |
|
| 1992 |
Leco KJ, Hayden LJ, Sharma RR, Rocheleau H, Greenberg AH, Edwards DR. Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts. Gene. 117: 209-17. PMID 1639268 DOI: 10.1016/0378-1119(92)90731-4 |
0.443 |
|
| 1992 |
Urbanski SJ, Edwards DR, Maitland A, Leco KJ, Watson A, Kossakowska AE. Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas. British Journal of Cancer. 66: 1188-94. PMID 1457364 DOI: 10.1038/Bjc.1992.434 |
0.376 |
|
| 1992 |
Edwards DR, Rocheleau H, Sharma RR, Wills AJ, Cowie A, Hassell JA, Heath JK. Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription. Biochimica Et Biophysica Acta. 1171: 41-55. PMID 1420363 DOI: 10.1016/0167-4781(92)90138-P |
0.359 |
|
| 1991 |
Mann JS, Kindy MS, Edwards DR, Curry TE. Hormonal regulation of matrix metalloproteinase inhibitors in rat granulosa cells and ovaries Endocrinology. 128: 1825-1832. PMID 1848503 DOI: 10.1210/Endo-128-4-1825 |
0.431 |
|
| 1991 |
Rathjen PD, Nichols J, Toth S, Edwards DR, Heath JK, Smith AG. Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations. Genes & Development. 4: 2308-18. PMID 1703981 DOI: 10.1101/Gad.4.12B.2308 |
0.358 |
|
| 1991 |
Denhardt DT, Edwards DR, Mcleod M, Norton G, Parfett CLJ, Zimmer M. Spontaneous immortalization of mouse embryo cells: Strain differences and changes in gene expression with particular reference to retroviral gag-pol genes Experimental Cell Research. 192: 128-136. PMID 1701724 DOI: 10.1016/0014-4827(91)90167-S |
0.342 |
|
| 1991 |
Kossakowska A, Urbanski S, Edwards D. Tissue inhibitor of metalloproteinases-1 (TIMP-1) RNA is expressed at elevated levels in malignant non-Hodgkin's lymphomas Blood. 77: 2475-2481. DOI: 10.1182/Blood.V77.11.2475.Bloodjournal77112475 |
0.475 |
|
| 1989 |
Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BL. Expression of genes for non-collagenous proteins during embryonic bone formation. Connective Tissue Research. 21: 31-5; discussion 36-. PMID 2691198 DOI: 10.3109/03008208909049993 |
0.336 |
|
| 1987 |
Edwards DR, Parfett CLJ, Smith JH, Denhardt DT. Evidence that post-transcriptional changes in the expression of mitogen regulated protein accompany immortalization of mouse cells Biochemical and Biophysical Research Communications. 147: 467-473. PMID 3632680 DOI: 10.1016/S0006-291X(87)80144-4 |
0.35 |
|
| 1987 |
Edwards DR, Murphy G, Reynolds JJ, Whitham SE, Docherty AJ, Angel P, Heath JK. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. The Embo Journal. 6: 1899-1904. DOI: 10.1002/J.1460-2075.1987.Tb02449.X |
0.387 |
|
| 1986 |
Milavetz BI, Edwards DR. Synthesis and stability of nuclear matrix proteins in resting and serum-stimulated Swiss 3T3 cells Journal of Cellular Physiology. 127: 388-396. PMID 3711149 DOI: 10.1002/Jcp.1041270306 |
0.399 |
|
| 1986 |
Denhardt DT, Edwards DR, Parfett CLJ. Gene expression during the mammalian cell cycle Bba - Reviews On Cancer. 865: 83-125. PMID 3533155 DOI: 10.1016/0304-419X(86)90024-7 |
0.301 |
|
| 1986 |
Edwards DR, Waterhouse P, Holman ML, Denhardt DT. A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: Evidence for inducible and constitutive transcripts Nucleic Acids Research. 14: 8863-8878. PMID 3024122 DOI: 10.1093/Nar/14.22.8863 |
0.353 |
|
| 1985 |
Parfett CL, Hamilton RT, Howell BW, Edwards DR, Nilsen-Hamilton M, Denhardt DT. Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines. Molecular and Cellular Biology. 5: 3289-92. PMID 3841805 DOI: 10.1128/Mcb.5.11.3289 |
0.317 |
|
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