☰

Qi-Yin Chen - Publications

Affiliations: 
2008-2012 University of Florida, Gainesville, Gainesville, FL, United States 
Tree Info Similar researchers PubMed Report error

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Banik P, Ray K, Kamps J, Chen QY, Luesch H, Winklhofer KF, Tatzelt J. VCP/p97 mediates nuclear targeting of non-ER-imported prion protein to maintain proteostasis. Life Science Alliance. 7. PMID 38570188 DOI: 10.26508/lsa.202302456  0.478
2024 Atanasova KR, Perkins CM, Ratnayake R, Jiang J, Chen QY, Schmittgen TD, Luesch H. Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids. Frontiers in Pharmacology. 15: 1335246. PMID 38510657 DOI: 10.3389/fphar.2024.1335246  0.752
2024 Kallifidas D, Dhakal D, Chen M, Chen QY, Kokkaliari S, Colon Rosa NA, Ratnayake R, Bruner SD, Paul VJ, Ding Y, Luesch H. Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer Drugs. Organic Letters. PMID 38330916 DOI: 10.1021/acs.orglett.3c04083  0.711
2023 Atanasova KR, Perkins CM, Ratnayake R, Jiang J, Chen QY, Schmittgen TD, Luesch H. Epigenetic Small-Molecule Screen for Inhibition and Reversal of Acinar Ductal Metaplasia in Mouse Pancreatic Organoids. Biorxiv : the Preprint Server For Biology. PMID 38077007 DOI: 10.1101/2023.11.27.567685  0.705
2023 Dhakal D, Kallifidas D, Chen M, Kokkaliari S, Chen QY, Paul VJ, Ding Y, Luesch H. Heterologous Production of the C33-C45 Polyketide Fragment of Anticancer Apratoxins in a Cyanobacterial Host. Organic Letters. PMID 36961224 DOI: 10.1021/acs.orglett.3c00462  0.756
2022 Pohl MO, Martin-Sancho L, Ratnayake R, White KM, Riva L, Chen QY, Lieber G, Busnadiego I, Yin X, Lin S, Pu Y, Pache L, Rosales R, Déjosez M, Qin Y, et al. Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity. Acs Infectious Diseases. PMID 35766385 DOI: 10.1021/acsinfecdis.2c00008  0.719
2022 Brumley DA, Gunasekera SP, Sauvage T, Dos Santos LAH, Chen QY, Paul VJ, Luesch H. Discovery, Synthesis, and Biological Evaluation of Anaenamides C and D from a New Marine Cyanobacterium, sp. Journal of Natural Products. PMID 35167289 DOI: 10.1021/acs.jnatprod.1c01073  0.584
2021 Cai W, Ratnayake R, Wang M, Chen QY, Raisch KP, Dang LH, Law BK, Luesch H. Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm. Current Research in Pharmacology and Drug Discovery. 2: 100053. PMID 34909679 DOI: 10.1016/j.crphar.2021.100053  0.783
2021 Qiu B, Tan A, Tan YZ, Chen QY, Luesch H, Wang X. Largazole Inhibits Ocular Angiogenesis by Modulating the Expression of VEGFR2 and p21. Marine Drugs. 19. PMID 34436310 DOI: 10.3390/md19080471  0.547
2021 Matthew S, Chen QY, Ratnayake R, Fermaintt CS, Lucena-Agell D, Bonato F, Prota AE, Lim ST, Wang X, Díaz JF, Risinger AL, Paul VJ, Oliva MÁ, Luesch H. Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33619102 DOI: 10.1073/pnas.2021847118  0.771
2021 Liang X, Chen QY, Seabra GM, Matthew S, Kwan JC, Li C, Paul VJ, Luesch H. Bifunctional Doscadenamides Activate Quorum Sensing in Gram-Negative Bacteria and Synergize with TRAIL to Induce Apoptosis in Cancer Cells. Journal of Natural Products. PMID 33480689 DOI: 10.1021/acs.jnatprod.0c01003  0.789
2020 Chen QY, Luo D, Seabra GM, Luesch H. Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7. Bioorganic & Medicinal Chemistry. 28: 115756. PMID 33002682 DOI: 10.1016/J.Bmc.2020.115756  0.787
2020 Al-Awadhi FH, Salvador-Reyes LA, Elsadek LA, Ratnayake R, Chen QY, Luesch H. Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases. Acs Chemical Neuroscience. PMID 32559056 DOI: 10.1021/Acschemneuro.0C00093  0.761
2020 Brumley DA, Gunasekera SP, Chen QY, Paul VJ, Luesch H. Discovery, Total Synthesis, and SAR of Anaenamides A and B: Anticancer Cyanobacterial Depsipeptides with a Chlorinated Pharmacophore. Organic Letters. PMID 32418432 DOI: 10.1021/Acs.Orglett.0C01281  0.601
2019 Bousquet MS, Ratnayake R, Pope JL, Chen QY, Zhu F, Chen S, Carney TJ, Gharaibeh RZ, Jobin C, Paul VJ, Luesch H. Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression. Free Radical Biology & Medicine. PMID 31536771 DOI: 10.1016/J.Freeradbiomed.2019.09.013  0.728
2019 Liang X, Matthew S, Chen QY, Kwan JC, Paul VJ, Luesch H. Discovery and Total Synthesis of Doscadenamide A: A Quorum Sensing Signaling Molecule from a Marine Cyanobacterium. Organic Letters. PMID 31414826 DOI: 10.1021/Acs.Orglett.9B02525  0.773
2019 Qiu B, Tan A, Veluchamy AB, Li Y, Murray H, Cheng W, Liu C, Busoy JM, Chen QY, Sistla S, Hunziker W, Cheung CMG, Wong TY, Hong W, Luesch H, et al. Apratoxin S4 Inspired by a Marine Natural Product, a New Treatment Option for Ocular Angiogenic Diseases. Investigative Ophthalmology & Visual Science. 60: 3254-3263. PMID 31361305 DOI: 10.1167/Iovs.19-26936  0.557
2018 Chen QY, Chaturvedi PR, Luesch H. Process Development and Scale-up Total Synthesis of Largazole, a Potent Class I Histone Deacetylase Inhibitor. Organic Process Research & Development. 22: 190-199. PMID 37332527 DOI: 10.1021/acs.oprd.7b00352  0.559
2018 Cai W, Ratnayake R, Gerber MH, Chen QY, Yu Y, Derendorf H, Trevino JG, Luesch H. Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model. Investigational New Drugs. PMID 30073464 DOI: 10.1007/S10637-018-0647-0  0.785
2018 Cai W, Matthew S, Chen QY, Paul VJ, Luesch H. Discovery of new A- and B-type laxaphycins with synergistic anticancer activity. Bioorganic & Medicinal Chemistry. PMID 29606488 DOI: 10.1016/J.Bmc.2018.03.022  0.775
2018 Chen Q, Chaturvedi PR, Luesch H. Process Development and Scale-up Total Synthesis of Largazole, a Potent Class I Histone Deacetylase Inhibitor Organic Process Research & Development. 22: 190-199. DOI: 10.1021/Acs.Oprd.7B00352  0.604
2017 Cai W, Chen QY, Dang LH, Luesch H. Correction to "Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors". Acs Medicinal Chemistry Letters. 8: 1342. PMID 29266134 DOI: 10.1021/Acsmedchemlett.7B00498  0.701
2017 Cai W, Salvador-Reyes LA, Zhang W, Chen QY, Matthew S, Ratnayake R, Seo SJ, Dolles S, Gibson DJ, Paul VJ, Luesch H. Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing. Acs Chemical Biology. PMID 29205032 DOI: 10.1021/Acschembio.7B00827  0.762
2017 Cai W, Chen QY, Dang LH, Luesch H. Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors. Acs Medicinal Chemistry Letters. 8: 1007-1012. PMID 29057042 DOI: 10.1021/Acsmedchemlett.7B00192  0.716
2016 Wu P, Cai W, Chen QY, Xu S, Yin R, Li Y, Zhang W, Luesch H. Total Synthesis and Biological Evaluation of Apratoxin E and Its C30 Epimer: Configurational Reassignment of the Natural Product. Organic Letters. PMID 27723359 DOI: 10.1021/Acs.Orglett.6B02780  0.691
2015 Luo D, Chen QY, Luesch H. Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases. The Journal of Organic Chemistry. PMID 26709602 DOI: 10.1021/Acs.Joc.5B02386  0.8
2014 Salvador LA, Park H, Al-Awadhi FH, Liu Y, Kim B, Zeller SL, Chen QY, Hong J, Luesch H. Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties. Acs Medicinal Chemistry Letters. 5: 905-10. PMID 25147612 DOI: 10.1021/Ml500170R  0.767
2014 Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Evaluation of class I HDAC isoform selectivity of largazole analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3728-31. PMID 25070421 DOI: 10.1016/J.Bmcl.2014.07.006  0.766
2014 Chen QY, Liu Y, Cai W, Luesch H. Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity. Journal of Medicinal Chemistry. 57: 3011-29. PMID 24660812 DOI: 10.1021/Jm4019965  0.766
2014 Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Largazole pharmacokinetics in rats by LC-MS/MS. Marine Drugs. 12: 1623-40. PMID 24658499 DOI: 10.3390/Md12031623  0.736
2011 Chen QY, Liu Y, Luesch H. Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity. Acs Medicinal Chemistry Letters. 2: 861-865. PMID 22081789 DOI: 10.1021/Ml200176M  0.725
Show low-probability matches.